NIH PAR · NIGMS · R16
PAR-25-414: Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The SuRE program supports research capacity building at eligible higher education institutions by funding investigator-initiated biomedical research inbasic, social, clinical, behavioral, or translational science that falls in the mission areas of the NIH. The purpose of SuRE awards is to provide support for investigator-initiated research at resource-limited institutions by full-time faculty who are not currently funded by any NIH Research Project Grants (RPGs) with the exception of SuRE or SuRE-First awards, to furnish students with high-quality undergraduate and/or graduate research experiences, and to enhance the institutional scientific research culture.
- NOFO number
- PAR-25-414
- Type
- PAR
- Activity code
- R16
- Primary institute
- NIGMS · National Institute of General Medical Sciences
- Clinical trials
- Not Allowed
- Posted
- Jun 13, 2025
- Opens
- Aug 29, 2025
- Expires
- Sep 8, 2028
PAR-25-414 due dates
3 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Application Due Date(s) | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| September 29, 2025 | September 29, 2025 | January 07, 2026 * | March 2026 | May 2026 | July 2026 |
| May 27, 2026 | May 27, 2026 | Not Applicable | November 2026 | January 2027 | April 2027 |
| September 28, 2026 | September 28, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
| May 28, 2027 | May 28, 2027 | Not Applicable | November 2027 | January 2028 | April 2028 |
| September 28, 2027 | September 28, 2027 | Not Applicable | March 2028 | May 2028 | July 2028 |
| May 29, 2028 | May 29, 2028 | Not Applicable | November 2028 | January 2029 | April 2029 |
Projects funded under PAR-25-414
NIH RePORTER lists 65 projects funded under PAR-25-414 in FY2022–FY2026, with $12.7M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
65
Distinct projects, FY2022–FY2026
New awards
62
Type 1 (new project) award records
NIH funding
$12.7M
Award dollars under PAR-25-414, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 65 | 62 | $12.7M |
Institutions with the most funding
- University of North Texas$1.0M · 4 projects
- East Tennessee State University$903K · 3 projects
- Rochester Institute of Technology$847K · 3 projects
- Queens College$755K · 2 projects
- University of Puerto Rico Med Sciences$745K · 3 projects
- Marshall University$737K · 5 projects
- California State Univ-Dominguez Hills$637K · 1 project
- Midwestern State University$535K · 1 project
Funding institutes
- NIGMS$3.6M · 22
- NIAID$2.8M · 20
- NINDS$2.7M · 5
- NEI$1.2M · 2
- NIA$452K · 3
- NIAAA$292K · 2
- NIBIB$290K · 2
- NIEHS$281K · 2
Activity codes funded
- R1665 records
Most recent new awards
- Phytol and alcohol-associated liver disease (opens NIH RePORTER)
Marshall University · 1R16AA033317-01 · NIAAA · Notice Sep 18, 2026
$147KR16
- TopoROP: Multi-View Topology-Integrated Analytics for Diagnosis of Retinopathy of Prematurity (opens NIH RePORTER)
Queens College · 1R16EY039206-01 · NEI · Notice Sep 17, 2026
$604KR16
- Utilizing Membrane Protein Chaperones as Therapeutics to Prevent and Disrupt Protein Aggregation in Parkinson’s disease (opens NIH RePORTER)
Midwestern State University · 1R16NS151382-01A1 · NINDS · Notice Sep 17, 2026
$535KR16
- Development of a Biopolymer Hydrogel as a Long-Term Vitreous Substitute (opens NIH RePORTER)
California State Univ-Dominguez Hills · 1R16EY039197-01 · NEI · Notice Sep 17, 2026
$637KR16
- Navigating the Heterogeneous ECM via Topographical Priming (opens NIH RePORTER)
Rochester Institute of Technology · 1R16GM165482-01 · NIGMS · Notice Sep 14, 2026
$576KR16
- ORBIL-AI: Orthogonality-Regularized Biomedical Information-theoretic Learning (opens NIH RePORTER)
Morgan State University · 1R16LM015384-01 · NLM · Notice Sep 14, 2026
$130KR16
What its predecessor PAR-24-144 funded
PAR-25-414 reissues PAR-24-144. Its funding history is the best guide to who wins under this program: 46 projects and $13.6M in FY2022–FY2026.
Projects funded
46
Distinct projects, FY2022–FY2026
New awards
46
Type 1 (new project) award records
NIH funding
$13.6M
Award dollars under PAR-24-144, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 44 | 44 | $7.2M |
| FY2026 | 44 | 2 | $6.4M |
Institutions with the most funding
- Nova Southeastern University$906K · 3 projects
- San Francisco State University$620K · 2 projects
- Rowan University School/Osteopathic Med$616K · 1 project
- St. John's University$611K · 2 projects
- University of Nevada Las Vegas$593K · 2 projects
- University of Puerto Rico Med Sciences$592K · 1 project
- California State Univ San Bernardino$588K · 2 projects
- Howard University$583K · 2 projects
Funding institutes
- NIGMS$9.3M · 64
- NIAID$1.4M · 10
- NIDCR$1.2M · 2
- NINDS$784K · 6
- NEI$599K · 4
- NIDDK$233K · 2
Activity codes funded
- R1688 records
Most recent new awards
- Androgens protect against development of immune responses to peanut (opens NIH RePORTER)
University of Nebraska Kearney · 1R16AI192268-01 · NIAID · Notice May 28, 2026
$127KR16
- Examining the mechanisms underlying Libby Amphibole associated autoimmunity (opens NIH RePORTER)
Idaho State University · 1R16AI192264-01 · NIAID · Notice Apr 17, 2026
$139KR16
- Elucidating the mechanisms of Glis3-regulated development in the pancreas and kidney (opens NIH RePORTER)
Murray State University · 1R16DK147815-01 · NIDDK · Notice Sep 12, 2025
$116KR16
- Unveiling Mechanisms of ZIKV-Induced Cardiac Dysfunction in a mouse model (opens NIH RePORTER)
Howard University · 1R16AI189452-01 · NIAID · Notice Sep 9, 2025
$155KR16
- Using natural products to decipher essential host-parasite interactions in visceral leishmaniasis. (opens NIH RePORTER)
Fort Lewis College · 1R16AI189394-01 · NIAID · Notice Sep 8, 2025
$130KR16
- Immunoglobulin Repertoire Analysis of Tumor Infiltrating B cells in a Metastatic HER2 Positive Breast Cancer Mouse Model (opens NIH RePORTER)
Texas Southern University · 1R16GM159781-01 · NIGMS · Notice Sep 3, 2025
$170KR16
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
20 NIH institutes and offices take applications under PAR-25-414. Contact the program officer at the institute that fits your research before applying.
- NIGMS · National Institute of General Medical Sciences
- NEI · National Eye Institute
- NHGRI · National Human Genome Research Institute
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NIAID · National Institute of Allergy and Infectious Diseases
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
- NIBIB · National Institute of Biomedical Imaging and Bioengineering
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
- NIDCD · National Institute on Deafness and Other Communication Disorders
- NIDCR · National Institute of Dental and Craniofacial Research
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- NIDA · National Institute on Drug Abuse
- NIEHS · National Institute of Environmental Health Sciences
- NIMH · National Institute of Mental Health
- NINDS · National Institute of Neurological Disorders and Stroke
- NINR · National Institute of Nursing Research
- NIMHD · National Institute on Minority Health and Health Disparities
- NLM · National Library of Medicine
- NCI · National Cancer Institute
Related notices
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Notices of Special Interest (NOSIs)
NIH has attached 1 NOSI to PAR-25-414; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.
Award terms
- Application types allowed
- NewRenewalResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Applications may request up to 100,000 in direct costs per year, excluding consortium facilities and administrative F&A) costs.
- Project period
- The scope of the proposed project should determine the project period. The maximum period of support is 4 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the number of meritorious applications received.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PAR-24-144.
- Companion NOFOs: PAR-25-415.
Other open NOFOs for R16
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.