NIH PAR · NIMHD · R01
PAR-25-299: Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This initiative will support multi-level and/or multi-domain intervention research to reduce disparities in liver diseases and liver cancer among populations who experience health disparities in the United States (U.S.). This NOFO is being reissued in accordance with the simplified review criteria in effect for application due dates after January 25, 2025.
- NOFO number
- PAR-25-299
- Type
- PAR
- Activity code
- R01
- Primary institute
- NIMHD · National Institute on Minority Health and Health Disparities
- Clinical trials
- Optional
- Posted
- Dec 5, 2024
- Opens
- Jan 5, 2025
- Expires
- Jan 8, 2028
PAR-25-299 due dates
2 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Application Due Date(s) | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| February 05, 2024 | March 05, 2024 * | Not Applicable | July 2024 | October 2024 | December 2024 |
| June 05, 2024 | July 05, 2024 * | Not Applicable | November 2024 | January 2025 | April 2025 |
| October 05, 2024 | November 05, 2024 * | Not Applicable | March 2025 | May 2025 | July 2025 |
| February 05, 2025 | March 05, 2025 * | Not Applicable | July 2025 | October 2025 | December 2025 |
| June 05, 2025 | July 05, 2025 * | Not Applicable | November 2025 | January 2026 | April 2026 |
| October 05, 2025 | November 05, 2025 * | Not Applicable | March 2026 | May 2026 | July 2026 |
| February 05, 2026 | March 05, 2026 * | Not Applicable | July 2026 | October 2026 | December 2026 |
| June 05, 2026 | July 05, 2026 * | Not Applicable | November 2026 | January 2027 | April 2027 |
| October 05, 2026 | November 05, 2026 * | Not Applicable | March 2027 | May 2027 | July 2027 |
| February 05, 2027 | March 05, 2027 * | Not Applicable | July 2027 | October 2027 | December 2027 |
| June 05, 2027 | July 05, 2027 * | Not Applicable | November 2027 | January 2028 | April 2028 |
Funded projects
NIH RePORTER lists no awards under PAR-25-299 in FY2022–FY2026. Awards usually appear a few months after the first review cycle.
Participating institutes
3 NIH institutes and offices take applications under PAR-25-299. Contact the program officer at the institute that fits your research before applying.
- NIMHD · National Institute on Minority Health and Health Disparities
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NCI · National Cancer Institute
Related notices
Mar 31, 2025 · NOT-OD-24-084
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Award terms
- Application types allowed
- NewResubmission The OER Glossary https://grants.nih.gov/grants/glossary.htm) and the SF424 R&R) Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.  The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are…
- Award budget
- Application budgets are not limited but need to reflect the actual needs of the proposed project. 
- Project period
- The scope of the proposed project should determine the project period. The maximum project period is 5 years.  NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PAR-24-207.
Other open NOFOs for R01
- PAR-25-317Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)NIMHD · next due Feb 5, 2027
- PAR-24-330Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)NIMHD · next due Feb 5, 2027
- PAR-25-292The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)NIMHD · next due Feb 5, 2027
- PAR-24-273Advancing Healthcare for Older Adults from Populations that Experience Health Disparities (R01 - Clinical Trial Optional)NIMHD · next due Feb 5, 2027
- PAR-25-371Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)NHGRI · next due Oct 20, 2026
- PAR-25-379Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)NIDA · next due Oct 21, 2026
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.