NIH PA · NIH · K23
PA-24-185: Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of individuals with a clinical doctoral degree who have made a commitment to focus their research endeavors on patient-oriented research.
- NOFO number
- PA-24-185
- Type
- PA
- Activity code
- K23
- Primary institute
- NIH
- Clinical trials
- Not Allowed
- Posted
- Apr 9, 2024
- Opens
- May 10, 2024
- Expires
- May 8, 2027
PA-24-185 due dates
No application due dates remain in the listed cycles. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Letter of Intent Due Date(s) |
|---|
| Not Applicable |
| June 12, 2024 |
| July 12, 2024 * |
| September 07, 2024 * |
| November 2024 |
| January 2025 |
| April 2025 |
| October 12, 2024 |
| November 12, 2024 * |
| January 07, 2025 * |
| March 2025 |
| May 2025 |
| July 2025 |
| February 12, 2025 |
| March 12, 2025 * |
| May 07, 2025 * |
| July 2025 |
| October 2025 |
| December 2025 |
| June 12, 2025 |
| July 12, 2025 * |
| September 07, 2025 * |
| November 2025 |
| January 2026 |
Projects funded under PA-24-185
NIH RePORTER lists 244 projects funded under PA-24-185 in FY2022–FY2026, with $65.3M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
244
Distinct projects, FY2022–FY2026
New awards
244
Type 1 (new project) award records
NIH funding
$65.3M
Award dollars under PA-24-185, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 90 | 90 | $17.3M |
| FY2026 | 242 | 154 | $47.9M |
Institutions with the most funding
- University of California, San Francisco$3.5M · 14 projects
- Children's Hosp of Philadelphia$2.9M · 10 projects
- University of Pittsburgh at Pittsburgh$2.3M · 9 projects
- Johns Hopkins University$2.3M · 8 projects
- Yale University$2.3M · 8 projects
- Massachusetts General Hospital$2.0M · 7 projects
- Utah State Higher Education System--University of Utah$2.0M · 5 projects
- Stanford University$1.9M · 5 projects
Funding institutes
- NHLBI$12.3M · 67
- NIAID$8.3M · 44
- NINDS$8.2M · 37
- NIDDK$7.9M · 39
- NICHD$7.0M · 39
- NIMH$6.4M · 25
- NIA$4.6M · 26
- NIDA$2.5M · 13
Activity codes funded
- K23332 records
Most recent new awards
- Mechanisms of Spinal Stiffening After Growing Rod Insertion (opens NIH RePORTER)
Children's Hosp of Philadelphia · 1K23AR086373-01A1 · NIAMS · Notice Sep 23, 2026
$160KK23
- Implementing Human-Centered AI in Acute Care to Facilitate PrEP Delivery (opens NIH RePORTER)
University of Alabama at Birmingham · 1K23DA067349-01 · NIDA · Notice Sep 17, 2026
$200KK23
- Understanding the Effect of Perinatal Cash Transfers on Birth Outcomes and Infant Health (opens NIH RePORTER)
University of Michigan at Ann Arbor · 1K23HD123254-01 · NICHD · Notice Sep 17, 2026
$167KK23
- Mechanisms and phenotypes of cognitive dysfunction in pediatric-onset systemic lupus erythematosus (opens NIH RePORTER)
University of Colorado Denver · 1K23AR088555-01 · NIAMS · Notice Sep 17, 2026
$170KK23
- Mechanisms of incomplete treatment responses to type 2 inhibitors in asthma (opens NIH RePORTER)
University of California, San Francisco · 1K23HL181329-01A1 · NHLBI · Notice Sep 17, 2026
$191KK23
- Left Ventricular Dysfunction, Cognition, and Brain Aging in a Multi-Ethnic Cohort (opens NIH RePORTER)
Columbia University Health Sciences · 1K23AG095295-01A1 · NIA · Notice Sep 17, 2026
$194KK23
What its predecessor PA-20-205 funded
PA-24-185 reissues PA-20-205. Its funding history is the best guide to who wins under this program: 607 projects and $410.6M in FY2022–FY2026.
Projects funded
607
Distinct projects, FY2022–FY2026
New awards
487
Type 1 (new project) award records
NIH funding
$410.6M
Award dollars under PA-20-205, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 283 | 163 | $51.2M |
| FY2023 | 434 | 149 | $78.2M |
| FY2024 | 549 | 137 | $99.2M |
| FY2025 | 567 | 38 | $102.6M |
| FY2026 | 443 | 0 | $79.4M |
Institutions with the most funding
- University of California, San Francisco$23.9M · 36 projects
- Johns Hopkins University$20.7M · 28 projects
- Massachusetts General Hospital$17.3M · 26 projects
- University of Pennsylvania$17.0M · 26 projects
- Brigham and Women's Hospital$12.9M · 19 projects
- University of Michigan at Ann Arbor$12.9M · 19 projects
- Yale University$11.9M · 18 projects
- Emory University$11.0M · 18 projects
Funding institutes
- NHLBI$77.1M · 435
- NIAID$48.0M · 271
- NIMH$45.1M · 241
- NINDS$41.8M · 207
- NIDDK$38.6M · 211
- NIA$31.3M · 175
- NICHD$27.2M · 172
- NIAMS$23.5M · 148
Activity codes funded
- K232,276 records
Most recent new awards
- Deciphering the molecular landscape of frontotemporal lobar degeneration: A network-based proteomic approach (opens NIH RePORTER)
University of California, San Francisco · 1K23AG090757-01 · NIA · Notice Sep 10, 2025
$200KK23
- Proteomic profiling for proteins associated with intracranial atherosclerotic disease. (opens NIH RePORTER)
Duke University · 1K23HL177307-01 · NHLBI · Notice Aug 18, 2025
$159KK23
- Causal Gene Prioritization in Systemic Sclerosis: Multi-Omics Analyses from Population Genetics to Single Cell Biology (opens NIH RePORTER)
Columbia University Health Sciences · 1K23AR084061-01 · NIAMS · Notice Aug 15, 2025
$173KK23
- Improving prediction of persistent hypoxemic respiratory failure to support clinical trial enrichment (opens NIH RePORTER)
University of Washington · 1K23HL168162-01A1 · NHLBI · Notice Aug 13, 2025
$186KK23
- Pain Assessment, Treatment, and Functional Outcomes in Hospitalized, Older Adults (opens NIH RePORTER)
University of California, San Francisco · 1K23AG084899-01A1 · NIA · Notice Aug 13, 2025
$183KK23
- Inflammatory Responses, Fibrotic Mediators, and Comorbidity Burden as Determinants of Myocardial Dysfunction and Heart Failure in Rheumatoid Arthritis (opens NIH RePORTER)
University of Nebraska Medical Center · 1K23AR085189-01 · NIAMS · Notice Aug 12, 2025
$172KK23
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
22 NIH institutes and offices take applications under PA-24-185. Contact the program officer at the institute that fits your research before applying.
- NIH
- NHLBI · National Heart, Lung, and Blood Institute
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NIAID · National Institute of Allergy and Infectious Diseases
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
- NIBIB · National Institute of Biomedical Imaging and Bioengineering
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
- NIDCD · National Institute on Deafness and Other Communication Disorders
- NIDCR · National Institute of Dental and Craniofacial Research
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- NIDA · National Institute on Drug Abuse
- NIEHS · National Institute of Environmental Health Sciences
- NIGMS · National Institute of General Medical Sciences
- NIMH · National Institute of Mental Health
- NINDS · National Institute of Neurological Disorders and Stroke
- NINR · National Institute of Nursing Research
- NIMHD · National Institute on Minority Health and Health Disparities
- NCCIH · National Center for Complementary and Integrative Health
- ORWH
- ODSS
- NEI · National Eye Institute
Related notices
Nov 24, 2025 · NOT-DE-26-013
Notice of Rescheduled NIDCR Pre-Application and Technical Assistance Webinars on Applying for Fellowship F) Awards and Career Development K) Awards.
Sep 25, 2025 · NOT-DE-26-012
Notice of NIDCR Pre-Application and Technical Assistance Webinars on Applying for Fellowship F) Awards and Career Development K) Awards.
Mar 31, 2025
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.
Apr 4, 2024 · NOT-OD-24-084
Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025.
Nov 12, 2024 · NOT-DK-25-002
Updated NIDDK Guidance for NIDDKs Mentored Clinical Scientist Research Career Development Award K08) and Mentored Patient-Oriented Research Career Development Award K23): Percent Effort of Surgeon-Scientists; PA-24-182; PA-24-184; PA-24-185.
Sep 4, 2024 · NOT-OD-24-168
Notice of Correction to the Eligible Individuals PD/PI) Section for the NIHsParent Mentored Patient-Oriented ResearchCareer Development Award Parent K23s) and the Midcareer Investigator Award in Patient-Oriented Research ParentK24s).
Jun 4, 2024 · NOT-MD-24-017
Guidance Regarding Reduction of Effort for NIMHD Individual Mentored K Awards.
May 2, 2024
Notice to Extend the
Notices of Special Interest (NOSIs)
NIH has attached 32 NOSIs to PA-24-185; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.
Award terms
- Application types allowed
- NewResubmissionRevision The OER Glossary and the How to Apply - Application Guide provides details on these application types.
- Award budget
- Information
- Project period
- The total project period may not exceed 5 years. Other
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PA-20-205.
- Companion NOFOs: PA-24-184, PA-24-186.
Other open NOFOs for K23
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.