KK Series — Career Development

NIH K23 Grants — Mentored Patient-Oriented Research Career Development Award

Reviewed by Dr. Meng ZhaoLast reviewed June 9, 2026Data refreshed September 5, 2026Editorial standards

Mentored training for clinicians doing patient-oriented research

Funding

Salary support + ~$30K research/year

Duration

3–5 years

Eligibility

Clinicians focused on patient-oriented research

Activity code

K23

What is the NIH K23 grant?

The K23 is the NIH career development award for clinicians doing patient-oriented research — clinical trials, observational studies, behavioral interventions, and other research that directly involves human subjects. Like K08, it provides 75% protected research time and a research allowance for 3–5 years.

Recent K23 awards from NIH RePORTER

Examples of funded K23 projects across the last two fiscal years. The matching-award count comes from the full result set; funding totals, averages, rankings, and examples use the first 500 records returned by NIH RePORTER. Figures reflect a snapshot last refreshed on September 5, 2026.

Matching awards (last 2 FYs)
2,398
Full matching record count on RePORTER
Sampled funding
$88.8M
Sum of award amounts in the sample
Average award
$178K
Mean award amount in the sample

Example K23 projects from the sample

  • Impact of Health Deductible Health Plans on the Evaluation, Treatment, and Outcomes for Acute Coronary Syndrome

    5K23HL164970-04
    Shih-Chuan Chou · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA · $167,471 · awarded Aug 26, 2026 · NIH

    PROJECT ABSTRACT This K23 award will enable the candidate, Shih-Chuan Chou, MD, MPH, SM, to become an independent physician-scientist focused on the effect of out-of-pocket costs on care utilization and outcomes of acute chest pain and cardiovascular care. Chest pain is one of the most common reasons for emergency department (ED) evaluation, with over 7…

  • TARGET-VIPeR: Testing And Response in Guideline-Engaged Treatment of Viral Respiratory Infections in Pediatric High-Risk Patients

    1K23AI202237-01
    Claire Abraham · BOSTON CHILDREN'S HOSPITAL, MA · $194,400 · awarded Aug 25, 2026 · NIH

    PROJECT SUMMARY/ABSTRACT Candidate: Dr. Claire Abraham is a practicing pediatrician in the Division of General Pediatrics at Boston Children’s Hospital (BCH). She completed her pediatrics residency at NewYork-Presbyterian/Columbia University, and General Academic Pediatrics and T32-funded pediatric health services research fellowships at BCH. Building on…

  • Bacteriophage as a predictive biomarker in chronic Pseudomonas airway disease

    5K23HL169902-04
    Elizabeth Burgener · CHILDREN'S HOSPITAL OF LOS ANGELES, CA · $199,044 · awarded Aug 25, 2026 · NIH

    PROJECT SUMMARY / ABSTRACT Despite major advances in therapy, pulmonary disease continues to dominate the clinical course of patients with cystic fibrosis (CF). All patients with CF develop chronic lung infections, with Pseudomonas aeruginosa (Pa) becoming a predominant organism in adulthood. Even in the face of chronic inhalational antibiotic therapy to…

  • Adaptation, Feasibility, and Cost of Navigation for Prioritized Alcohol Treatment after Hospitalization (NavPATH)

    1K23AA033445-01
    Eden Bernstein · UNIVERSITY OF COLORADO DENVER, CO · $191,509 · awarded Aug 24, 2026 · NIH

    PROJECT SUMMARY/ABSTRACT Over 2 million US adults with alcohol use disorder (AUD) are hospitalized each year, yet less than half receive post-hospitalization AUD treatment. Current hospital-based approaches, including brief intervention and referral to treatment, are ineffective at improving post-hospitalization linkage to care for patients with AUD.…

  • Developing Patient-Centered Decision Support for Eosinophilic Esophagitis

    3K23DK129784-05S1
    Joy CHANG · UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI · $75,327 · awarded Aug 24, 2026 · NIH

    PROJECT SUMMARY Candidate’s Long-term Career Goal: To become an independently funded physician-scientist developing and testing patient-centered interventions to support shared decision making (SDM) in chronic esophageal diseases. Research Context: As a chronic disease with rapidly rising prevalence, incidence, healthcare costs, and burdens to patient…

  • Development and assessment of an HIV disclosure intervention for men

    5K23MH126771-05
    Pooja Chitneni · BRIGHAM AND WOMEN'S HOSPITAL, MA · $162,339 · awarded Aug 24, 2026 · NIH

    PROJECT SUMMARY Background: Disclosure of HIV is a key step in prevention, however, few evidence-based resources exist to support HIV disclosure among men with HIV. Candidate: My long-term goal is to become an independent, NIH-funded clinical researcher dedicated to interventions to support HIV and sexually transmitted infection prevention and treatment in…

  • The Effect of Exercise on T Cell Aging in Rheumatoid Arthritis

    5K23AG080066-03
    Brian Andonian · DUKE UNIVERSITY, NC · $160,062 · awarded Aug 21, 2026 · NIH

    Abstract Exercise training is linked to beneficial effects on maladaptive immune aging. In patients with rheumatoid arthritis (RA), exercise training is a disease modulating therapy and may improve premature biological aging inherent in RA, however, the mechanisms by which exercise benefits immune health is poorly understood. Improved knowledge of the…

  • Development and Pilot testing of a Theory-informed, Implementation Science Behavioral Modification Intervention supporting Care Planning in Patients with End-stage Liver Disease

    1K23DK146187-01A1
    Cristal Brown · UNIVERSITY OF TEXAS AT AUSTIN, TX · $187,398 · awarded Aug 20, 2026 · NIH

    PROJECT SUMMARY Dr. Brown, an Assistant Professor of Medicine in the Division of Gastroenterology and Hepatology at UT Austin Dell Medical School, is a transplant hepatologist with a long-term career goal of being a leader in care planning intervention development supporting improvement in the quality of life of all patients with end-stage liver disease…

  • Multi-Omics Approaches for the Diagnosis and Risk Stratification of Pulmonary Fibrosis-Associated Pulmonary Hypertension

    5K23HL181383-02
    Adam Brownstein · UNIVERSITY OF CALIFORNIA LOS ANGELES, CA · $175,306 · awarded Aug 20, 2026 · NIH

    Project Summary This is an application for a K23 award for Adam J Brownstein, MD, MS, a Pulmonary and Critical Care physician at the University of California, Los Angeles. The goal of this proposal is for Dr. Brownstein to establish himself as independent investigator in patient-oriented research in the field of pulmonary hypertension, with a focus on…

  • A Multi-Component Remote Care Intervention for Rural Patients Living with Heart Failure

    5K23HL179489-02
    Stephen Clarkson · UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL · $170,601 · awarded Aug 20, 2026 · NIH

    Heart failure (HF), a condition associated with increased hospitalizations, cost, and mortality, is a large and growing contributor to the mortality gap between rural and urban populations in the United States. Individuals living in rural communities face significantly higher mortality from HF than those in urban communities. Without the development of…

  • Dissecting the Heterogeneous Molecular Mechanisms Underlying Multiple Sclerosis Progression

    5K23NS140543-02
    Ahmed Abdelhak · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA · $198,928 · awarded Aug 18, 2026 · NIH

    Abstract Multiple sclerosis is the most common cause of non-traumatic disability in young adults, with an estimated total economic burden of $85.4 billion. Irreversible disability accumulation is the most challenging, unmet need in care for people with multiple sclerosis (pwMS) and drives socioeconomic burden. Disability accumulates in two different…

  • Administrative Supplement to: Applying digital phenotypes and epigenetics to understand clinical outcomes in acute hypoxemic respiratory failure without acute respiratory distress syndrome (NAHRF)

    3K23HL177334-02S1
    Cosby Arnold · UNIVERSITY OF CALIFORNIA AT DAVIS, CA · $75,600 · awarded Aug 18, 2026 · NIH

    PROJECT SUMMARY This administrative supplement application requests $70,000 in direct costs for 12 months to sustain progress on my NHLBI-funded K23 project during a qualifying critical life event (childbirth). The parent K23 applies (1) EHR-derived prediction modeling, (2) machine learning subphenotyping, and (3) whole methylome profiling to study the…

Funding institutes in the sample

InstituteAwardsFunding
NIH500$88.8M

Most frequent institutions in the sample

  1. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — 31 awards
  2. UNIVERSITY OF PENNSYLVANIA — 26 awards
  3. MASSACHUSETTS GENERAL HOSPITAL — 25 awards
  4. JOHNS HOPKINS UNIVERSITY — 16 awards
  5. UNIVERSITY OF COLORADO DENVER — 16 awards
  6. UNIVERSITY OF MICHIGAN AT ANN ARBOR — 16 awards
  7. BRIGHAM AND WOMEN'S HOSPITAL — 16 awards
  8. UNIVERSITY OF PITTSBURGH AT PITTSBURGH — 13 awards

Source: NIH RePORTER. Verify any award in the official record by searching its project number. See our data methodology for how this sample is built and its limitations.

Decision guide

Choose K23 when

Choose K23 when your research directly involves human subjects: trials, registries, biobanks, behavioral interventions.

Choose another mechanism when

Choose K08 for primarily lab-based research even if you're a clinician.

Who applies for K23

Clinicians within ~5 years of training completion who plan a research career focused on patient-oriented investigation.

Compare nearby NIH grant mechanisms

Searchers often land on K23 while deciding between adjacent NIH activity codes. Compare scope, NIH staff involvement, budget scale, and applicant stage before choosing a funding opportunity.

For broad grant lookup, use the NIH grant search to find funded examples by activity code, PI, institution, and award year.

Search tips for K23

  • K23 awards are useful predictors of clinical trial PIs in early career.

Open NIH NOFOs for K23

NIH accepts K23 applications only through a notice of funding opportunity (NOFO). These 2 are open or opening soon; each page lists due dates, participating institutes, related notices, and the projects NIH funded under it.

See all open K23 NOFOs

Search NIH grants by activity code

Find K23-funded PIs

K23 funding trends

K23 frequently asked questions

What is the difference between K08 and K23?

K08 = lab research for clinicians. K23 = patient-oriented research for clinicians. Both are 3–5 year mentored awards with 75% effort.

Related NIH grant types