NIH PA · NIH · K08
PA-24-181: Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research.
- NOFO number
- PA-24-181
- Type
- PA
- Activity code
- K08
- Primary institute
- NIH
- Clinical trials
- Required
- Posted
- Apr 24, 2024
- Opens
- May 10, 2024
- Expires
- May 8, 2027
PA-24-181 due dates
No application due dates remain in the listed cycles. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Letter of Intent Due Date(s) |
|---|
| Not Applicable |
| June 12, 2024 |
| July 12, 2024 * |
| September 07, 2024 * |
| November 2024 |
| January 2025 |
| April 2025 |
| October 12, 2024 |
| November 12, 2024 * |
| January 07, 2025 * |
| March 2025 |
| May 2025 |
| July 2025 |
| February 12, 2025 |
| March 12, 2025 * |
| May 07, 2025 * |
| July 2025 |
| October 2025 |
| December 2025 |
| June 12, 2025 |
| July 12, 2025 * |
| September 07, 2025 * |
| November 2025 |
| January 2026 |
Projects funded under PA-24-181
NIH RePORTER lists 14 projects funded under PA-24-181 in FY2022–FY2026, with $4.6M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
14
Distinct projects, FY2022–FY2026
New awards
14
Type 1 (new project) award records
NIH funding
$4.6M
Award dollars under PA-24-181, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 6 | 6 | $1.4M |
| FY2026 | 14 | 8 | $3.2M |
Institutions with the most funding
- University of Washington$761K · 2 projects
- St. Jude Children's Research Hospital$580K · 1 project
- UT Southwestern Medical Center$499K · 1 project
- Rutgers Biomedical and Health Sciences$444K · 1 project
- University of Tx MD Anderson Can Ctr$420K · 1 project
- Duke University$356K · 1 project
- University of California, San Francisco$306K · 1 project
- Sloan-Kettering Inst Can Research$252K · 1 project
Funding institutes
- NCI$4.3M · 18
- NIBIB$191K · 1
- NIMHD$188K · 1
Activity codes funded
- K0820 records
Most recent new awards
- Adaptation of a Multilevel Intervention to Improve Employment Outcomes among Young Adult Cancer Survivors (opens NIH RePORTER)
University of Rochester · 1K08CA304529-01A1 · NCI · Notice Sep 8, 2026
$207KK08
- Adaptation of an Evidence-Based Goals of Care Communication Intervention for Adolescent and Young Adult Cancer Patients (opens NIH RePORTER)
Sloan-Kettering Inst Can Research · 1K08CA313764-01 · NCI · Notice Sep 3, 2026
$252KK08
- A Pilot RCT of a Digitally-Enhanced Community Health Worker-led Intervention for Early Stepped Palliative Care in Hepatobiliary Cancers (opens NIH RePORTER)
Loma Linda University · 1K08MD021861-01 · NIMHD · Notice Sep 1, 2026
$188KK08
- Implementing a team-based care model to increase cervical cancer screening uptake in low-resource primary care settings (opens NIH RePORTER)
University of Washington · 1K08CA317629-01 · NCI · Notice Aug 27, 2026
$204KK08
- SleepCARE: A multimodal behavioral intervention for reducing sleep disturbance in caregivers of patients with primary malignant brain tumors (opens NIH RePORTER)
Massachusetts General Hospital · 1K08CA308869-01A1 · NCI · Notice Aug 25, 2026
$225KK08
- Alternative Perioperative Strategies to Control Cerebral Edema (opens NIH RePORTER)
University of Louisville · 1K08CA308845-01 · NCI · Notice Jul 15, 2026
$212KK08
What its predecessor PA-20-202 funded
PA-24-181 reissues PA-20-202. Its funding history is the best guide to who wins under this program: 65 projects and $53.5M in FY2022–FY2026.
Projects funded
65
Distinct projects, FY2022–FY2026
New awards
54
Type 1 (new project) award records
NIH funding
$53.5M
Award dollars under PA-20-202, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 32 | 21 | $6.5M |
| FY2023 | 38 | 8 | $8.1M |
| FY2024 | 61 | 22 | $13.1M |
| FY2025 | 62 | 3 | $13.9M |
| FY2026 | 55 | 0 | $11.9M |
Institutions with the most funding
- Massachusetts General Hospital$6.6M · 6 projects
- Dana-Farber Cancer Inst$4.1M · 5 projects
- Sloan-Kettering Inst Can Research$3.6M · 4 projects
- Johns Hopkins University$2.4M · 3 projects
- University of Colorado Denver$1.9M · 3 projects
- Yale University$1.9M · 2 projects
- St. Jude Children's Research Hospital$1.9M · 2 projects
- University of California, San Francisco$1.8M · 2 projects
Funding institutes
- NCI$46.1M · 204
- NIMH$3.0M · 19
- NIDA$1.7M · 9
- NIMHD$1.3M · 8
- NHLBI$1.0M · 6
- NINDS$381K · 2
Activity codes funded
- K08248 records
Most recent new awards
- A digital health parent coaching intervention to improve neurodevelopmental outcomes for young childhood cancer survivors in underserved communities (opens NIH RePORTER)
Research Inst Nationwide Children's Hosp · 1K08CA290060-01A1 · NCI · Notice Feb 19, 2025
$186KK08
- Defining mechanisms of immunotherapy resistance and targeting TIGIT in hepatobiliary cancers (opens NIH RePORTER)
UT Southwestern Medical Center · 1K08CA290062-01A1 · NCI · Notice Jan 29, 2025
$271KK08
- Neurophysiology of Reward Signaling in Parkinson's Disease (opens NIH RePORTER)
Vanderbilt University Medical Center · 1K08NS140767-01 · NINDS · Notice Dec 16, 2024
$191KK08
- Community health worker implementation of transdiagnostic evidence-based treatment in Spanish: Advancing mental health equity for Latine parents (opens NIH RePORTER)
University of Illinois at Chicago · 1K08MD020100-01 · NIMHD · Notice Sep 19, 2024
$177KK08
- Adaptation and Testing of an Evidence-Based Sexual Health Communication Skills Training Intervention for Patients with Prostate Cancer (opens NIH RePORTER)
New York University School of Medicine · 1K08CA293275-01 · NCI · Notice Sep 3, 2024
$182KK08
- Improving CAR T-cell therapy for Pediatric B-cell Acute Lymphoblastic Leukemia (B-ALL) (opens NIH RePORTER)
St. Jude Children's Research Hospital · 1K08CA279927-01A1 · NCI · Notice Aug 28, 2024
$289KK08
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
19 NIH institutes and offices take applications under PA-24-181. Contact the program officer at the institute that fits your research before applying.
- NIH
- NHLBI · National Heart, Lung, and Blood Institute
- NHGRI · National Human Genome Research Institute
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NIBIB · National Institute of Biomedical Imaging and Bioengineering
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
- NIDCD · National Institute on Deafness and Other Communication Disorders
- NIDA · National Institute on Drug Abuse
- NIEHS · National Institute of Environmental Health Sciences
- NIMH · National Institute of Mental Health
- NINDS · National Institute of Neurological Disorders and Stroke
- NIMHD · National Institute on Minority Health and Health Disparities
- NLM · National Library of Medicine
- NCCIH · National Center for Complementary and Integrative Health
- NCI · National Cancer Institute
- NEI · National Eye Institute
- ORWH
- ODSS
Related notices
Jan 22, 2026 · NOT-NS-26-030
Notice of Early Expiration of NIH HEAL Initiative PainCare Clinician Training Program PCTP): Mentored Clinical Scientist Development Awards K08/K23).
Mar 31, 2025
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.
Apr 4, 2024 · NOT-OD-24-084
Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025.
Jun 5, 2025 · NOT-EY-24-010
NEI Notice of Participation in PA-24-181, Mentored Clinical Scientist Research Career Development Award Parent K08 Independent Clinical Trial Required)".
Jun 4, 2024 · NOT-MD-24-017
Guidance Regarding Reduction of Effort for NIMHD Individual Mentored K Awards.
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Notices of Special Interest (NOSIs)
NIH has attached 28 NOSIs to PA-24-181; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.
Award terms
- Application types allowed
- NewResubmissionRevision The OER Glossary and the How to Apply - Application Guide provides details on these application types.
- Award budget
- Information
- Project period
- The total project period may not exceed 5 years. Other
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PA-20-202.
- Companion NOFOs: PA-24-182, PA-24-183.
Other open NOFOs for K08
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.