NIH PA · NIH · 332

PA-23-317: Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsExpires Nov 24, 2026

The National Institutes of Health (NIH) hereby notifies NIH award recipients that funds may be available for revision applications to support the expansion of existing projects and/or programs within the awarding IC identified in the competitive revision Notice of Special Interest (NOSI). Applications for Revisions will be evaluated for scientific and technical merit by (an) appropriate Scientific Review Group(s), in accordance with NIH peer review policy and procedures, using the stated review criteria. Only applications submitted in response to a NOSI published by an NIH Institute or Center will be allowed to apply to this NOFO.

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PA-23-317
Type
PA
Activity code
332
Primary institute
NIH
Clinical trials
Optional
Posted
Nov 24, 2023
Opens
Nov 22, 2023
Expires
Nov 24, 2026

PA-23-317 due dates

No application due dates remain in the listed cycles. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PA-23-317
Letter of Intent Due Date(s)
Not Applicable
Not Applicable

Projects funded under PA-23-317

NIH RePORTER lists 24 projects funded under PA-23-317 in FY2022–FY2026, with $8.5M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

24

Distinct projects, FY2022–FY2026

New awards

0

Type 1 (new project) award records

NIH funding

$8.5M

Award dollars under PA-23-317, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PA-23-317
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202580$3.8M
FY2026160$4.7M

Institutions with the most funding

  1. University of Minnesota$641K · 2 projects
  2. Emory University$427K · 2 projects
  3. University of Florida$399K · 1 project

Funding institutes

  • NHLBI$2.3M · 4
  • NIBIB$970K · 3
  • NIA$967K · 3
  • NIMH$961K · 3
  • NIMHD$693K · 2
  • NIEHS$684K · 2
  • NCI$492K · 2
  • NIAID$335K · 1

Activity codes funded

  • R0119 records
  • U243 records
  • R151 record
  • R241 record

What its predecessor PA-20-163 funded

PA-23-317 reissues PA-20-163. Its funding history is the best guide to who wins under this program: 1 project and $94K in FY2022–FY2026.

Projects funded

1

Distinct projects, FY2022–FY2026

New awards

0

Type 1 (new project) award records

NIH funding

$94K

Award dollars under PA-20-163, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PA-20-163
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202410$94K
FY202500$0
FY202600$0

Institutions with the most funding

  1. Stanford University$94K · 1 project

Funding institutes

  • NHGRI$94K · 1

Activity codes funded

  • U241 record

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

18 NIH institutes and offices take applications under PA-23-317. Contact the program officer at the institute that fits your research before applying.

  • NIH
  • FIC · Fogarty International Center
  • NHGRI · National Human Genome Research Institute
  • NIAAA · National Institute on Alcohol Abuse and Alcoholism
  • NIAID · National Institute of Allergy and Infectious Diseases
  • NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
  • NIDA · National Institute on Drug Abuse
  • NIEHS · National Institute of Environmental Health Sciences
  • NIMH · National Institute of Mental Health
  • NIMHD · National Institute on Minority Health and Health Disparities
  • NCCIH · National Center for Complementary and Integrative Health
  • NCATS · National Center for Advancing Translational Sciences
  • NCI · National Cancer Institute
  • NIA · National Institute on Aging
  • NEI · National Eye Institute
  • NIDCR · National Institute of Dental and Craniofacial Research
  • ODSS

Related notices

  1. Jun 23, 2025 · NOT-DE-26-002

    Notice of Participation of the National Institute of Dental and Craniofacial Research NIDCR) in PA-23-317, Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements Clinical Trial Optional).

  2. May 9, 2025 · NOT-OD-25-116

    Notice to Applicants That the Simplified Review Framework Will be Applied to All Relevant Applications for August/October 2025 Councils. See Notice NOT-OD-25-116.-->

  3. Mar 31, 2025

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.

  4. Jan 13, 2025 · NOT-EY-25-005

    NEI Notice of Participation in PA-23-317, Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements Clinical Trial Optional)".

  5. Apr 4, 2024 · NOT-OD-24-084

    Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025.

  6. Nov 13, 2024 · NOT-MH-25-010

    Notice of Special Interest NOSI): NIMH Funding for Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements.

  7. Aug 14, 2024 · NOT-AG-24-059

    Notice of Participation of the National Institute on Aging in PA-23-317, Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements Clinical Trial Optional)".

  8. Jun 10, 2024 · NOT-ES-24-013

    Notice of Participation of the National Institute of Environmental Health Sciences NIEHS) in PA-23-317..

  9. Feb 29, 2024 · NOT-AI-24-034

    Notice of Participation of the National Institute of Allergy and Infectious Diseases NIAID) in PA-23-317, Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements Clinical Trial Optional) . See Notices NOT-AI-24-034

  10. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023.

  11. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy.

Notices of Special Interest (NOSIs)

NIH has attached 6 NOSIs to PA-23-317; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.

Award terms

Application types allowed
Revision Competitive revision applications to active NIH parent awards. The OER Glossary and the SF424 R&R) Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Specific budget limits may be specified in the competitive revision NOSI. Application budgets must be reasonable and must reflect the actual needs of the proposed project.
Project period
The project and budget periods must be within the currently approved project period for the existing parent award. Unless otherwise instructed in the competitive revision NOSI, applicants may request up to two years of support. The parent award must have a minimum of two years remaining within the current project period at the time of application submission. NIH grants policies as described in…
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PA-20-163.

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO