NIH PA · NIH · K25
PA-24-191: Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.This Funding Opportunity Announcement (FOA) is designed specifically for applicants…
- NOFO number
- PA-24-191
- Type
- PA
- Activity code
- K25
- Primary institute
- NIH
- Clinical trials
- Not Allowed
- Posted
- Apr 23, 2024
- Opens
- May 10, 2024
- Expires
- May 8, 2027
PA-24-191 due dates
No application due dates remain in the listed cycles. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Letter of Intent Due Date(s) |
|---|
| Not Applicable |
| June 12, 2024 |
| July 12, 2024 * |
| September 07, 2024 * |
| November 2024 |
| January 2025 |
| April 2025 |
| October 12, 2024 |
| November 12, 2024 * |
| January 07, 2025 * |
| March 2025 |
| May 2025 |
| July 2025 |
| February 12, 2025 |
| March 12, 2025 * |
| May 07, 2025 * |
| July 2025 |
| October 2025 |
| December 2025 |
| June 12, 2025 |
| July 12, 2025 * |
| September 07, 2025 * |
| November 2025 |
| January 2026 |
Projects funded under PA-24-191
NIH RePORTER lists 19 projects funded under PA-24-191 in FY2022–FY2026, with $3.2M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
19
Distinct projects, FY2022–FY2026
New awards
19
Type 1 (new project) award records
NIH funding
$3.2M
Award dollars under PA-24-191, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 4 | 4 | $582K |
| FY2026 | 17 | 15 | $2.6M |
Institutions with the most funding
- Massachusetts General Hospital$359K · 2 projects
- University of Texas at Austin$292K · 1 project
- Weill Medical Coll of Cornell Univ$225K · 2 projects
- University of Tx MD Anderson Can Ctr$192K · 1 project
- Rice University$190K · 1 project
- Vanderbilt University Medical Center$175K · 1 project
- University of Houston$168K · 1 project
- Stanford University$164K · 1 project
Funding institutes
- NHLBI$1.1M · 8
- NCI$718K · 4
- NIA$444K · 3
- NIDDK$292K · 2
- NIDCR$164K · 1
- NIAID$162K · 1
- NIGMS$142K · 1
- NICHD$132K · 1
Activity codes funded
- K2521 records
Most recent new awards
- Three-Dimensional Hydrogel Models for Analyzing Cariogenic Bacterial and Antimicrobial Responses (opens NIH RePORTER)
Ada Forsyth Institute, Inc. · 1K25DE035216-01A1 · NIDCR · Notice Sep 16, 2026
$164KK25
- Machine Learning for Prediction of Failure of the Autoresuscitation Reflex in SIDS (opens NIH RePORTER)
Baylor College of Medicine · 1K25HL188354-01 · NHLBI · Notice Sep 4, 2026
$135KK25
- Intelligent Bioelectronic Implants for the Diagnosis and Neuromodulation of Neurogenic Bladder Dysfunction (opens NIH RePORTER)
University of Houston · 1K25DK144708-01A1 · NIDDK · Notice Aug 27, 2026
$168KK25
- Ultra-Low Field MRI for Assessment of Congenital Heart Disease (opens NIH RePORTER)
Vanderbilt University Medical Center · 1K25HL183904-01A1 · NHLBI · Notice Aug 19, 2026
$175KK25
- Uncovering the unique roles of bone-forming osteoblasts and bone endothelial cells in organ-specific metastasis of breast cancer to bone (opens NIH RePORTER)
Stanford University · 1K25CA304623-01A1 · NCI · Notice Aug 19, 2026
$164KK25
- Translational XR and AI Technologies with Dynamic Soft Robotic Hearts for Immersive Clinical Training and Future Intraoperative Guidance in Interventional Cardiology (opens NIH RePORTER)
Weill Medical Coll of Cornell Univ · 1K25HL186244-01 · NHLBI · Notice Aug 19, 2026
$101KK25
What its predecessor PA-20-199 funded
PA-24-191 reissues PA-20-199. Its funding history is the best guide to who wins under this program: 53 projects and $27.7M in FY2022–FY2026.
Projects funded
53
Distinct projects, FY2022–FY2026
New awards
39
Type 1 (new project) award records
NIH funding
$27.7M
Award dollars under PA-20-199, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 23 | 12 | $3.2M |
| FY2023 | 35 | 12 | $5.2M |
| FY2024 | 46 | 12 | $6.8M |
| FY2025 | 48 | 3 | $7.0M |
| FY2026 | 37 | 0 | $5.5M |
Institutions with the most funding
- Brigham and Women's Hospital$3.6M · 6 projects
- Columbia University Health Sciences$1.9M · 3 projects
- Johns Hopkins University$1.6M · 3 projects
- Cleveland Clinic Lerner Com-Cwru$1.5M · 3 projects
- University of Pittsburgh at Pittsburgh$1.4M · 3 projects
- Wake Forest University Health Sciences$1.3M · 3 projects
- Massachusetts General Hospital$1.3M · 3 projects
- Icahn School of Medicine at Mount Sinai$1.2M · 2 projects
Funding institutes
- NIA$7.1M · 51
- NHLBI$6.2M · 39
- NIDDK$3.6M · 23
- NIBIB$2.5M · 16
- NCI$2.3M · 13
- NIAID$1.6M · 14
- NICHD$1.2M · 9
- NIAMS$1.0M · 9
Activity codes funded
- K25189 records
Most recent new awards
- Resolving phenotypic overlap in renal carcinoma subtypes using multi-tiered network methods (opens NIH RePORTER)
Dana-Farber Cancer Inst · 1K25CA297149-01 · NCI · Notice May 7, 2025
$172KK25
- Microscopy characterization of a novel tau model of Alzheimer's Disease in monkeys (opens NIH RePORTER)
University of California at Davis · 1K25AG086663-01A1 · NIA · Notice Nov 18, 2024
$110KK25
- Cerebral Small Vessel Disease and Dementia: Defining Global Resilience and Disruption in Brain Networks (opens NIH RePORTER)
Wake Forest University Health Sciences · 1K25AG090707-01 · NIA · Notice Nov 15, 2024
$137KK25
- Understanding Utilization of Diabetes Self-Management Education and Support Using Social Network Analysis (opens NIH RePORTER)
Univ of Arkansas for Med Scis · 1K25DK136966-01A1 · NIDDK · Notice Aug 21, 2024
$143KK25
- Use of gold-based photothermal nanomaterials for the comminution of kidney stones (opens NIH RePORTER)
Cleveland Clinic Lerner Com-Cwru · 1K25DK138120-01A1 · NIDDK · Notice Aug 19, 2024
$135KK25
- Optimizing Congenital Aortic Valve Surgery with Simulation-Guided Design (opens NIH RePORTER)
Stanford University · 1K25HL175208-01 · NHLBI · Notice Aug 16, 2024
$181KK25
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
19 NIH institutes and offices take applications under PA-24-191. Contact the program officer at the institute that fits your research before applying.
- NIH
- NEI · National Eye Institute
- NHLBI · National Heart, Lung, and Blood Institute
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NIAID · National Institute of Allergy and Infectious Diseases
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
- NIBIB · National Institute of Biomedical Imaging and Bioengineering
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
- NIDCD · National Institute on Deafness and Other Communication Disorders
- NIDCR · National Institute of Dental and Craniofacial Research
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- NIDA · National Institute on Drug Abuse
- NIEHS · National Institute of Environmental Health Sciences
- NIGMS · National Institute of General Medical Sciences
- NCI · National Cancer Institute
- NLM · National Library of Medicine
- ORWH
- ODSS
Related notices
Nov 24, 2025 · NOT-DE-26-013
Notice of Rescheduled NIDCR Pre-Application and Technical Assistance Webinars on Applying for Fellowship F) Awards and Career Development K) Awards.
Sep 25, 2025 · NOT-DE-26-012
Notice of NIDCR Pre-Application and Technical Assistance Webinars on Applying for Fellowship F) Awards and Career Development K) Awards.
Mar 31, 2025
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.
Apr 4, 2024 · NOT-OD-24-084
Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025.
Nov 25, 2024 · NOT-LM-24-007
Notice of NLM Participation on PA-24-191 Mentored Quantitative Research Development Award Parent K25 Independent Clinical Trial Not Allowed)". SeeNotice NOT-LM-24-007.
Aug 30, 2024 · NOT-HG-24-046
Notice of NHGRI Withdrawal of Participation From PA-24-191 Mentored QuantitativeResearch Development Award Parent K25Independent Clinical Trial Not Allowed)". SeeNotice NOT-HG-24-046.
May 30, 2024 · NOT-DA-24-032
Notice to Alert the Public of NIDA's Career Development Award Salary Limits.
May 7, 2024 · NOT-AI-24-038
Notice of Information: NIAID to Increase K99, K25, and K01 Salary and Research Support and R00 Years of Support.
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Notices of Special Interest (NOSIs)
NIH has attached 11 NOSIs to PA-24-191; 1 are active. A NOSI flags a topic an institute wants to fund through this NOFO.
- Notice to Alert the Public of NIDA's Career Development Award Salary LimitsNOT-DA-24-032 · NIDA · until Oct 16, 2026
Award terms
- Application types allowed
- NewResubmissionRevision The OER Glossary and the How to Apply - Application Guide provides details on these application types.
- Award budget
- Information
- Project period
- The total project period may not exceed 5 years. Other
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PA-20-199.
- Companion NOFOs: PA-24-190, PA-24-192.
Other open NOFOs for K25
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.