NIH PA · NIH · K01
PA-24-176: Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances. Other ICs use the K01 to support career…
- NOFO number
- PA-24-176
- Type
- PA
- Activity code
- K01
- Primary institute
- NIH
- Clinical trials
- Not Allowed
- Posted
- Apr 24, 2024
- Opens
- May 12, 2024
- Expires
- May 8, 2027
PA-24-176 due dates
No application due dates remain in the listed cycles. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Letter of Intent Due Date(s) |
|---|
| Not Applicable |
| June 12, 2024 |
| July 12, 2024 * |
| September 07, 2024 * |
| November 2024 |
| January 2025 |
| April 2025 |
| October 12, 2024 |
| November 12, 2024 * |
| January 07, 2025 * |
| March 2025 |
| May 2025 |
| July 2025 |
| February 12, 2025 |
| March 12, 2025 * |
| May 07, 2025 * |
| July 2025 |
| October 2025 |
| December 2025 |
| June 12, 2025 |
| July 12, 2025 * |
| September 07, 2025 * |
| November 2025 |
| January 2026 |
Projects funded under PA-24-176
NIH RePORTER lists 217 projects funded under PA-24-176 in FY2022–FY2026, with $49.1M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
217
Distinct projects, FY2022–FY2026
New awards
217
Type 1 (new project) award records
NIH funding
$49.1M
Award dollars under PA-24-176, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 77 | 76 | $12.5M |
| FY2026 | 211 | 141 | $36.5M |
Institutions with the most funding
- University of Pittsburgh at Pittsburgh$2.6M · 9 projects
- Johns Hopkins University$2.0M · 6 projects
- Boston University Medical Campus$1.9M · 6 projects
- Univ of North Carolina Chapel Hill$1.8M · 6 projects
- Washington University$1.5M · 6 projects
- Icahn School of Medicine at Mount Sinai$1.4M · 4 projects
- Utah State Higher Education System--University of Utah$1.3M · 4 projects
- University of Washington$1.3M · 6 projects
Funding institutes
- NIDDK$9.3M · 62
- NIDA$7.8M · 36
- NIMH$7.1M · 25
- NIA$6.3M · 50
- NHLBI$4.7M · 29
- NIAID$4.3M · 27
- NCI$2.5M · 14
- NIAAA$2.0M · 12
Activity codes funded
- K01288 records
Most recent new awards
- Monitoring M.tuberculosis through community wastewater (opens NIH RePORTER)
Stanford University · 1K01AI199468-01 · NIAID · Notice Sep 18, 2026
$155KK01
- Maternal History of Childhood Maltreatment and Perinatal Cardiometabolic Health (opens NIH RePORTER)
University of Rochester · 1K01HD120749-01A1 · NICHD · Notice Sep 17, 2026
$130KK01
- Real-time posttraumatic stress symptoms and neural circuits of emotion regulation after trauma (opens NIH RePORTER)
Duke University · 1K01MH141469-01A1 · NIMH · Notice Sep 17, 2026
$178KK01
- Epitranscriptomic Regulation of DNA Double-Strand Breaks Repair in Mouse and Human Hippocampal Dentate Granule Neurons (opens NIH RePORTER)
University of Pennsylvania · 1K01AG092909-01A1 · NIA · Notice Sep 17, 2026
$128KK01
- PREDICT: Deep Learning Models for forecasting in Rheumatoid Arthritis (opens NIH RePORTER)
University of California, San Francisco · 1K01AR085707-01A1 · NIAMS · Notice Sep 17, 2026
$132KK01
- An essential role of TRIM21 in inflammasome assembly and autoinflammatory disease. (opens NIH RePORTER)
Cedars-Sinai Medical Center · 1K01AR087011-01A1 · NIAMS · Notice Sep 16, 2026
$116KK01
What its predecessor PA-20-190 funded
PA-24-176 reissues PA-20-190. Its funding history is the best guide to who wins under this program: 582 projects and $302.7M in FY2022–FY2026.
Projects funded
582
Distinct projects, FY2022–FY2026
New awards
495
Type 1 (new project) award records
NIH funding
$302.7M
Award dollars under PA-20-190, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 250 | 166 | $35.2M |
| FY2023 | 396 | 157 | $55.6M |
| FY2024 | 525 | 141 | $74.3M |
| FY2025 | 522 | 31 | $74.9M |
| FY2026 | 429 | 0 | $62.8M |
Institutions with the most funding
- Washington University$11.0M · 21 projects
- Johns Hopkins University$9.9M · 20 projects
- Massachusetts General Hospital$9.8M · 20 projects
- Stanford University$9.1M · 21 projects
- University of California, San Francisco$8.9M · 16 projects
- Columbia University Health Sciences$8.1M · 17 projects
- University of Pittsburgh at Pittsburgh$7.1M · 14 projects
- Emory University$7.0M · 16 projects
Funding institutes
- NIA$61.0M · 497
- NIDA$43.5M · 253
- NIMH$42.5M · 250
- NIDDK$36.9M · 264
- NHLBI$25.9M · 162
- NIAID$17.8M · 142
- NIMHD$16.9M · 136
- NIAAA$15.2M · 95
Activity codes funded
- K012,122 records
Most recent new awards
- Genotypic and phenotypic approaches to subtype individuals with coronary heart disease (opens NIH RePORTER)
University of Alabama at Birmingham · 1K01HL171839-01A1 · NHLBI · Notice Sep 24, 2025
$159KK01
- Accumulation of Elevated Risk Associated with Treatment-Escalation Differences in patients with Type 2 Diabetes (ACCELERATED-T2D) (opens NIH RePORTER)
University of Illinois at Chicago · 1K01DK139458-01A1 · NIDDK · Notice Sep 12, 2025
$148KK01
- Purinergic Signaling in Intestinal Inflammation (opens NIH RePORTER)
Medical University of South Carolina · 1K01DK138364-01A1 · NIDDK · Notice Sep 3, 2025
$162KK01
- Senescent Cells Effects in Response to Pathogens (opens NIH RePORTER)
Cedars-Sinai Medical Center · 1K01AG090692-01 · NIA · Notice Sep 3, 2025
$125KK01
- Using machine learning to understand cardiopulmonary and renal end organ complications for individuals with SCD (opens NIH RePORTER)
Medical College of Wisconsin · 1K01HL169309-01A1 · NHLBI · Notice Aug 28, 2025
$146KK01
- Dysfunctional mechanisms of the mitochondrial redox-sensitive signaling response to exercise in aged skeletal muscle (opens NIH RePORTER)
University of Washington · 1K01AG086542-01A1 · NIA · Notice Aug 26, 2025
$121KK01
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
24 NIH institutes and offices take applications under PA-24-176. Contact the program officer at the institute that fits your research before applying.
- NIH
- NHLBI · National Heart, Lung, and Blood Institute
- NHGRI · National Human Genome Research Institute
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NIAID · National Institute of Allergy and Infectious Diseases
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
- NIBIB · National Institute of Biomedical Imaging and Bioengineering
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
- NIDCD · National Institute on Deafness and Other Communication Disorders
- NIDCR · National Institute of Dental and Craniofacial Research
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- NIDA · National Institute on Drug Abuse
- NIEHS · National Institute of Environmental Health Sciences
- NIMH · National Institute of Mental Health
- NINR · National Institute of Nursing Research
- NIMHD · National Institute on Minority Health and Health Disparities
- NLM · National Library of Medicine
- NCCIH · National Center for Complementary and Integrative Health
- NCI · National Cancer Institute
- NINDS · National Institute of Neurological Disorders and Stroke
- ORIP
- ORWH
- ODSS
Related notices
May 26, 2026 · NOT-NS-26-001
Notice of Change: NINDS Participation in Mentored Research Scientist Development Award Parent K01). See Notice NOT-NS-26-001. January 28, 2026 - NIH Removing AIDS Application Due Dates from NOFOs. See Notice NOT-OD-26-029.
Nov 24, 2025 · NOT-DE-26-013
Notice of Rescheduled NIDCR Pre-Application and Technical Assistance Webinars on Applying for Fellowship F) Awards and Career Development K) Awards.
Sep 25, 2025 · NOT-DE-26-012
Notice of NIDCR Pre-Application and Technical Assistance Webinars on Applying for Fellowship F) Awards and Career Development K) Awards.
Jul 9, 2025 · NOT-AI-25-038
Revised NIAID Policy Defining the Institute’s Use of the Mentored Research Scientist Development K01) Award.
Mar 31, 2025
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.
Apr 4, 2024 · NOT-OD-24-084
Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025.
Nov 12, 2024 · NOT-DK-25-001
Notice of Change in Eligibility Requirements for the NIDDK K01- PA-24-175 and PA-24-176.
Jun 4, 2024 · NOT-MD-24-017
Guidance Regarding Reduction of Effort for NIMHD Individual Mentored K Awards.
May 30, 2024 · NOT-DA-24-032
Notice to Alert the Public of NIDA's Career Development Award Salary Limits.
May 7, 2024 · NOT-AI-24-038
Notice of Information: NIAID to Increase K99, K25, and K01 Salary and Research Support and R00 Years of Support.
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Notices of Special Interest (NOSIs)
NIH has attached 48 NOSIs to PA-24-176; 1 are active. A NOSI flags a topic an institute wants to fund through this NOFO.
- Notice to Alert the Public of NIDA's Career Development Award Salary LimitsNOT-DA-24-032 · NIDA · until Oct 16, 2026
Award terms
- Application types allowed
- NewResubmissionRevision The OER Glossary and the How to Apply - Application Guide provides details on these application types.
- Award budget
- Information
- Project period
- The total project period may not exceed 5 years. Other
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PA-20-190.
- Companion NOFOs: PA-24-175, PA-24-177.
Other open NOFOs for K01
- PA-24-175Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)NIH
- PAR-24-149NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Clinical Trial Required)NIDCD
- PAR-24-159NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Independent Clinical Trial Not Allowed)NIDCD
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.