KK Series — Career Development

NIH K25 Grants — Mentored Quantitative Research Career Development Award

Reviewed by Dr. Meng ZhaoLast reviewed June 9, 2026Data refreshed June 9, 2026Editorial standards

Brings quantitative scientists (engineers, physicists) into biomedical research

Funding

Salary support + research support

Duration

3–5 years

Eligibility

Quantitative scientists transitioning to biomedical research

Activity code

K25

What is the NIH K25 grant?

The K25 funds engineers, physicists, computer scientists, and other quantitative researchers who want to apply their skills to biomedical research questions and need mentored training in a biomedical context.

Recent K25 awards from NIH RePORTER

Examples of funded K25 projects across the last two fiscal years. The matching-award count comes from the full result set; funding totals, averages, rankings, and examples use the first 500 records returned by NIH RePORTER. Figures reflect a snapshot last refreshed on June 9, 2026.

Matching awards (last 2 FYs)
85
Full matching record count on RePORTER
Sampled funding
$12.6M
Sum of award amounts in the sample
Average award
$148K
Mean award amount in the sample

Example K25 projects from the sample

  • Functional connectivity alterations among opioid users in treatment

    5K25DA055156-05
    Hyuntaek Oh · BAYLOR COLLEGE OF MEDICINE, TX · $178,027 · awarded Jun 5, 2026 · NIH

    PROJECT SUMMARY/ABSTRACT This proposed study is a step toward the career development goal of becoming an independent researcher who focused on the study of the functional connectivity alterations among opioid users. The opioid overdose results in almost 450,000 deaths during 1999-2018, and 128 people in the United States die every day from the opioid…

  • Machine Learning as a Tool to Predict Early and Chronic Graft Dysfunction after Lung Transplantation

    1K25HL186354-01
    Jason Brunson · UNIVERSITY OF FLORIDA, FL · $142,568 · awarded May 19, 2026 · NIH

    PROJECT SUMMARY Lung transplantation is the treatment of last resort for a large number of patients with end-stage lung diseases, but is complicated by a modest post-transplant survival. Mortality after transplantation is mostly driven by chronic lung allograft dysfunction (CLAD). An early complication of lung transplantation, primary graft dysfunction…

  • Flexible causal inference methods for estimating longitudinal effects of air pollution on chronic lung disease

    5K25ES034064-05
    Daniel Malinsky · COLUMBIA UNIVERSITY HEALTH SCIENCES, NY · $110,970 · awarded May 19, 2026 · NIH

    Abstract This application for a Mentored Quantitative Research Career Development Award has been submitted with the goal of supporting Dr. Malinsky’s career as a quantitative researcher at the intersection of biostatistics, epidemiology, and data science for environmental health. The training and research plan build on Dr. Malinsky’s quantitative…

  • Development of Dynamic Resting State Functional Connectivity Machine Learning Framework for Dementia

    5K25AG071840-05
    fei jiang · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA · $132,696 · awarded May 18, 2026 · NIH

    Project Summary/Abstract The objective of this proposal is to provide a robust course of training for Fei Jiang, Ph.D., a candidate with an excellent foundation in statistical and machine learning research, to enable her to become an independent investigator in the field of quantitative data analysis and statistical/machine learning methods development for…

  • Understanding Utilization of Diabetes Self-Management Education and Support Using Social Network Analysis

    5K25DK136966-03
    Mandana Rezaeiahari · UNIV OF ARKANSAS FOR MED SCIS, AR · $165,843 · awarded May 12, 2026 · NIH

    PROJECT SUMMARY Diabetes Self-Management Education and Support (DSMES) addresses the clinical, psychological, and behavioral aspects of care needed to successfully self-manage diabetes. Despite the proven value of the DSMES on patient outcomes, it remains underutilized. Only a small fraction of patients receive DSMES within a year of being diagnosed with…

  • Understanding Diabetes Heterogeneity via Mining Multimodality Interconnected Data

    5K25DK135913-04
    Ji (Carl) Yang · EMORY UNIVERSITY, GA · $171,310 · awarded May 12, 2026 · NIH

    Understanding Diabetes Heterogeneity via Mining Multimodality Interconnected Data Abstract. Diabetes is a prevalent and highly heterogeneous disease that incurs tremendous human, economic, and so- cial costs globally. Prediabetes and early-stage type 2 diabetes often do not have single strong indicates or symptoms, posing great challenges for early…

  • Imaging Synaptic Decline in Models of Alzheimer's Disease

    5K25AG086674-03
    Mariana Potcoava · UNIVERSITY OF ILLINOIS AT CHICAGO, IL · $152,277 · awarded May 1, 2026 · NIH

    Project Summary/Abstract As the most common neurodegenerative disease of dementia, Alzheimer’s disease (AD) causes progressive memory loss and cognitive impairment. AD has neither a clear pathogenesis nor effective treatments. Its progression is marked by loss of neurons at the time of diagnosis. The proximal causes of this loss are not well understood.…

  • The Impact of Problematic Smartphone Use on Behavioral and Neural Functioning

    1K25HD120751-01
    Nayoung Kim · COLUMBIA UNIVERSITY HEALTH SCIENCES, NY · $132,300 · awarded Apr 24, 2026 · NIH

    Project Summary Presently, approximately 95% of U.S. teens now own smartphones giving rise to growing concerns about excessive and compulsive use patterns of use. Although smartphones offer unprecedented opportunities for learning and connection, problematic smartphone use (PSU), which affects roughly one in four adolescents, manifests as compulsive…

  • Understanding the genomic basis of problematic alcohol use through integrative analysis of multi-omics data

    5K25AA030072-05
    Tan Hoang Nguyen · VIRGINIA COMMONWEALTH UNIVERSITY, VA · $179,230 · awarded Apr 21, 2026 · NIH

    This project seeks to further the understanding of the genomic etiology of alcohol use disorder (AUD). Genetic studies have identified loci associated with the disorder; however, the genetic architecture of AUD has not been fully explained. Currently, genome-wide variant data of the disorder are available for analysis, and functional genomic datasets are…

  • Imaging Vascular Function in Normal Aging, MCI, and Mild Dementia

    5K25AG083114-03
    Feng Xu · JOHNS HOPKINS UNIVERSITY, MD · $147,486 · awarded Apr 21, 2026 · NIH

    ABSTRACT This application aims to broaden the research expertise of Dr. Xu, who has a background in bioengineering, by delving into clinical research of neurodegenerative diseases. The goal is to support her pursuit of an independent research career focused on using advanced neuroimaging techniques to identify cognitive decline caused by vascular insults.…

  • Resolving phenotypic overlap in renal carcinoma subtypes using multi-tiered network methods

    5K25CA297149-02
    Marouen Ben Guebila · DANA-FARBER CANCER INST, MA · $167,543 · awarded Apr 3, 2026 · NIH

    PROJECT SUMMARY/ABSTRACT Small sample size in Translocation Renal Cell Carcinoma (tRCC), a rare cancer, hampers our ability to correctly diagnose this aggressive subtype and to provide patients with efficient therapies. The most important causes of tRCC misdiagnosis are its heterogenous presentation and overlap with other subtypes such as the major subtype,…

  • Modeling SARS-CoV-2 variant emergence from immunocompromised hosts

    1K25AI196259-01
    Katherine Owens · FRED HUTCHINSON CANCER CENTER, WA · $161,946 · awarded Apr 2, 2026 · NIH

    Project Summary/Abstract This proposal describes a five-year research training program that will facilitate my ongoing transition from an applied mathematician to an independent, quantitative, multidisciplinary biomedical researcher. I will work closely with clinicians, mathematical modelers, bioinformaticians, evolutionary biologists, virologists and…

Funding institutes in the sample

InstituteAwardsFunding
NIH85$12.6M

Most frequent institutions in the sample

  1. BRIGHAM AND WOMEN'S HOSPITAL 9 awards
  2. COLUMBIA UNIVERSITY HEALTH SCIENCES 6 awards
  3. JOHNS HOPKINS UNIVERSITY 5 awards
  4. WAKE FOREST UNIVERSITY HEALTH SCIENCES 5 awards
  5. UNIVERSITY OF FLORIDA 5 awards
  6. MASSACHUSETTS GENERAL HOSPITAL 5 awards
  7. WEILL MEDICAL COLL OF CORNELL UNIV 3 awards
  8. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI 3 awards

Source: NIH RePORTER. Verify any award in the official record by searching its project number. See our data methodology for how this sample is built and its limitations.

Decision guide

Choose K25 when

Choose K25 if your terminal degree is outside biomedical sciences and you need mentored time to learn the biomedical domain.

Choose another mechanism when

PhDs already trained in biomedical research should use K01 or K99/R00.

Who applies for K25

PhDs in engineering, physics, mathematics, computer science, etc., looking to transition into biomedical research.

Compare nearby NIH grant mechanisms

Searchers often land on K25 while deciding between adjacent NIH activity codes. Compare scope, NIH staff involvement, budget scale, and applicant stage before choosing a funding opportunity.

For broad grant lookup, use the NIH grant search to find funded examples by activity code, PI, institution, and award year.

Search tips for K25

  • K25 PIs often anchor computational and engineering departments at AMCs.

Search NIH grants by activity code

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K25 funding trends

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