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Found 44 principal investigators from 126 displayed projects for "K25" (2021–2026)

Opportunity Digest

Heuristic scoring to help trainees and job seekers prioritize which labs to inspect first.

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High-opportunity leads

1

Likely hiring signals

0

Training-friendly awards

19

Average opportunity score

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Shelley Han Liu

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

Good lead · 46/100
Likely hiring
Solid budget
Active award
$390,337
FY 2025

Project Title

The PFAS exposure burden calculator: A novel tool for cross-study harmonization, biomonitoring and report-back

Grant Number:

1R01ES035804-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/25/2025

End Date:

5/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Almost every person in the US has detectable levels of per- and polyfluoroalkyl substances (PFAS) in their blood. PFAS are a large class of >4,000 chemicals, known as toxic “forever chemicals”, that contribute to worse cardio-metabolic health, decreased immune functioning, and cancer...

Research Terms

<0-11 years old><Back><Behavior><Biological Markers><Biological Monitoring><Biometrics><Biometry><Biostatistics><Birth><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Calendar><Calibration><Cancers><Cellular Immune Function><Chemicals><Child><Child Youth><Childhood><Children (0-21)><Clinical><Cohort Studies><Computer software><Concurrent Studies><Data><Development><Diet><Dimensions><Dorsum><Education><Educational aspects><Engineering><Environmental Epidemiology><Environmental Exposure><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Habits><Health><Heterogeneity><Home><Human><Human Figure><Human body><Hydrogen Oxide><Individual><Industry><Investigators><Laboratories><Life><Life Style><Lifestyle><Link><Literature><Maintenance><Malignant Neoplasms><Malignant Tumor><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measures><Medicine><Meta-Analysis><Methodology><Methods><Modeling><Modern Man><Monitor><NHANES><NICHD><NIEHS><National Academy of Sciences><National Health and Nutrition Examination Survey><National Institute of Child Health and Human Development><National Institute of Environmental Health Sciences><Outcome><PFAS><Participant><Parturition><Pattern><Perinatal><Peripartum><Persons><Phase><Poly-fluoroalkyl substances><Production><Psychometrics><Publishing><Reporting><Research><Research Personnel><Researchers><Resistance><Resolution><Risk Assessment><Science><Sister><Software><Source><Staining method><Stains><Standardization><Statistical Methods><Sum><Temporal trend><Testing><Time><Time trend><Trends over time><United States National Academy of Sciences><Water><Work><bio-markers><biologic marker><biomarker><biomonitoring><cancer risk><cardiometabolic><cardiometabolism><clinical practice><consumer product><contaminated drinking water><developmental><diets><drinking water contamination><epidemiologic><epidemiological><geographic site><health data><high dimensionality><homes><immune function><kids><life span><lifespan><malignancy><manufacture><method development><multidisciplinary><neoplasm/cancer><novel><pediatric><perfluorinated alkyl substances><perfluoroalkyl substances><perfluoroalkylated substances><polyfluorinated alkyl substances><polyfluoroalkyl substances><resistant><resolutions><response><simulation><statistic methods><substance use><substance using><theories><tool><youngster>
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Jiheum Park

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Exploratory lead · 38/100
Very recent
Active award
Career award
$178,610
FY 2026

Project Title

Early Detection of Pancreatic Cancer with Human-in-the-Loop Deep Learning

Grant Number:

5K25CA267052-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2023

End Date:

4/30/2028

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to leverage deep-learning algorithms on Electronic Health Records (EHRs) to improve the early detection of pancreatic ductal adenocarcinoma (PDAC), a malignancy with high mortality and morbidity. Compared to other major types of cancer in the U.S. (e.g., colorectal, prost...

Research Terms

<AI system><Address><Adoption><Algorithms><Architecture><Artificial Intelligence><Bayesian Network><Black Box><Breast><Cancer Cause><Cancer Detection><Cancer Etiology><Cancers><Categories><Cell Communication and Signaling><Cell Signaling><Cessation of life><Clinical><Collection><Colon or Rectum><Colorectal><Computer Reasoning><Data><Data Collection><Data Set><Death><Development><Diagnosis><Diagnostic Findings><Drugs><Early Diagnosis><Electronic Health Record><Engineering / Architecture><Future><General Taxonomy><Generations><Genetic Risk><Goals><Grouping><Health Benefit><Health Care><Human><Individual><Institution><Intervention><Intracellular Communication and Signaling><Knowledge><Laboratories><Learning><Literature><Logistic Regressions><Lung><Lung Respiratory System><Machine Intelligence><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant neoplasm of pancreas><Medical><Medical Records><Medical center><Medication><Methodology><Methods><Modeling><Modern Man><Modernization><Morbidity><Neural Development><Obesity><Output><Pancreas Cancer><Pancreas Ductal Adenocarcinoma><Pancreatic Cancer><Pancreatic Ductal Adenocarcinoma><Pathway interactions><Patients><Performance><Pharmaceutical Preparations><Population><Predicting Risk><Procedures><Process><Prostate><Prostate Gland><Prostatic Gland><Protocol><Protocols documentation><Public Health><Questionnaires><Reporting><Research><Risk><Risk Assessment><Risk Factors><Series><Signal Transduction><Signal Transduction Systems><Signaling><Signs and Symptoms><Structure><Survey Instrument><Surveys><System><Taxonomy><Techniques><Text><Time><Tobacco Consumption><Tobacco use><Training><Universities><Visualization><adiposity><artificial neural net><artificial neural network><biological signal transduction><cancer type><clinical practice><clinical predictors><colorectum><computational neural network><computer based prediction><corpulence><deep learning><deep learning algorithm><deep learning based model><deep learning based neural network><deep learning method><deep learning model><deep learning neural network><deep learning strategy><deep neural net><deep neural network><developmental><drug/agent><early detection><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><forecasting risk><generative models><groupings><health data><high risk><human-in-the-loop><improved><innovate><innovation><innovative><malignancy><mortality><multi-modal data><multi-modal datasets><multi-modality><multimodal data><multimodal datasets><multimodality><neoplasm/cancer><neural net architecture><neural network architecture><neurodevelopment><new approaches><novel><novel approaches><novel strategies><novel strategy><pancreas imaging><pancreatic malignancy><pathway><patient variability><patient variation><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predicts risk><prevent><preventing><risk prediction><risk predictions><screening><screenings><synthetic neural network><tobacco product use><trend><variability between patients><variation between patients>
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Mariana Camelia Potcoava

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Exploratory lead · 38/100
Very recent
Active award
Career award
$152,277
FY 2026

Project Title

Imaging Synaptic Decline in Models of Alzheimer's Disease

Grant Number:

5K25AG086674-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract As the most common neurodegenerative disease of dementia, Alzheimer’s disease (AD) causes progressive memory loss and cognitive impairment. AD has neither a clear pathogenesis nor effective treatments. Its progression is marked by loss of neurons at the time of diagnosis. Th...

Research Terms

<4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><AD dementia><AD model><AD patients><AD risk><AD risk factor><APOE><APOE e3><APOE e4><APOE-ε4><APOEε4><Abscission><Action Potentials><Affect><Age><Aging><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's amyloid><Alzheimer's disease model><Alzheimer's disease patient><Alzheimer's disease risk><Alzheimer's patient><Alzheimers Dementia><Amentia><Aminalon><Aminalone><Ammon Horn><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Protein A4><Amyloid beta-Protein><Amyloid β><Amyloid β-Peptide><Amyloid β-Protein><Animal Model><Animal Models and Related Studies><Apo E Receptor><Apo-E><ApoE Receptor><ApoE protein><Apolipoprotein E><Apolipoprotein E Receptor><Apoptosis><Apoptosis Pathway><Applied Skills><Area><Autoregulation><Axon Terminals><Aβ><Behavioral><Body Tissues><Brain><Brain Nervous System><Brain region><Buffers><Calcium><Cell Communication and Signaling><Cell Signaling><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complex><Cornu Ammonis><Custom><Data><Defect><Degenerative Neurologic Disorders><Dementia><Detection><Deterioration><Diagnosis><Disease><Disorder><Disturbance in cognition><Dysfunction><Elements><Encephalon><Endothelium><Equilibrium><Event><Excision><Excitatory Synapse><Exocytosis><Extirpation><Failure><Fluorescence Agents><Fluorescent Agents><Fluorescent Dyes><Foundations><Functional disorder><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G-Protein-Coupled Receptors><GABA><GPCR><Genetic><Genetic Engineering><Genetic Engineering Biotechnology><Genetic Engineering Molecular Biology><Genetic predisposing factor><Genotype><Glutamates><Goals><Hippocampus><Holography><Homeostasis><Hortega cell><Image><Impaired cognition><Inflammatory Response><Intermediary Metabolism><Intracellular Communication and Signaling><Invaded><L-Glutamate><LDL-Receptor Related Protein 1><Laboratories><Light><Low Density Lipoprotein Receptor-Related Protein><Low-Density-Lipoprotein Receptor-Related Protein-1><Maps><Measures><Mediating><Memory><Memory Loss><Mentors><Metabolic Processes><Metabolism><Mice><Mice Mammals><Microglia><Microscope><Mitochondria><Modeling><Modernization><Murine><Mus><NSF attachment protein receptor><Nerve Cells><Nerve Degeneration><Nerve Impulse Transmission><Nerve Transmission><Nerve Unit><Nervous System Degenerative Diseases><Neural Cell><Neural Degenerative Diseases><Neural Transmission><Neural degenerative Disorders><Neurites><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neuron Degeneration><Neuronal Transmission><Neurons><Optics><Pathogenesis><Pathologic><Phase><Phenotype><Photoradiation><Phototoxicity><Physics><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Presynaptic Nerve Endings><Presynaptic Terminals><Primary Senile Degenerative Dementia><Probability><Process><Programmed Cell Death><Proteins><Pump><Recombinant DNA Technology><Removal><Research><Research Resources><Resolution><Resources><Role><SNAP receptor><SNARE><Sampling><Scanning><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Slice><Specialist><Stimulus><Surgical Removal><Synapses><Synaptic><Synaptic Boutons><Synaptic Terminals><Synaptic Transmission><Synaptic Vesicles><Time><Tissues><Training><Training Programs><Visualization><a beta peptide><abeta><absorption><aged brain><ages><aging brain><alpha-2-Macroglobulin Receptor><alpha2-Macroglobulin Signaling Receptor><alzheimer model><alzheimer risk><amyloid beta><amyloid-b protein><apo E-3><apo E-4><apo E3><apo E4><apo epsilon4><apoE epsilon 4><apoE-3><apoE-4><apoE3><apoE4><apolipoprotein E epsilon 4><apolipoprotein E-3><apolipoprotein E-4><apolipoprotein E3><apolipoprotein E4><axon signaling><axon-glial signaling><axonal signaling><balance><balance function><beta amyloid fibril><biological signal transduction><cognitive dysfunction><cognitive function><cognitive loss><customs><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><design><designing><disease model><disorder model><effective therapy><effective treatment><fluorescent dye/probe><gamma-Aminobutyric Acid><genetic risk factor><genetically engineered><gitter cell><glia signaling><glial signaling><glutamatergic><hippocampal><imaging><imaging approach><imaging based approach><inherited factor><instrument><irradiation><lectures><memory decline><mesoglia><microglial cell><microgliocyte><mitochondrial><model of animal><mouse model><murine model><nerve cell death><nerve cell loss><nerve signaling><neural><neural degeneration><neural signaling><neurodegeneration><neurodegenerative><neurodegenerative illness><neurological degeneration><neuron cell death><neuron cell loss><neuron death><neuron loss><neuronal><neuronal cell death><neuronal cell loss><neuronal circuit><neuronal circuitry><neuronal death><neuronal degeneration><neuronal loss><neuronal signaling><neurotransmission><neurotransmitter release><new approaches><novel approaches><novel strategies><novel strategy><optic imaging><optical><optical imaging><optical lattices><pathophysiology><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><perivascular glial cell><photonics><postsynaptic><presynaptic><primary degenerative dementia><programs><resection><resolutions><response><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><senile dementia of the Alzheimer type><sensor><sex><skills><social role><soluble N-ethylmaleimide-sensitive-factor attachment protein receptor><soluble amyloid precursor protein><spatial and temporal><spatial temporal><spatiotemporal><synapse><synapse function><synaptic function><voltage><γ-Aminobutyric Acid>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Abdallah M Eteleeb

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Exploratory lead · 38/100
Very recent
Active award
Career award
$148,581
FY 2026

Project Title

Identification and characterization of molecular subtypes of Alzheimer's disease associated with cognitive function through cross-omics data integration

Grant Number:

5K25AG083057-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/15/2023

End Date:

4/30/2028

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract The goal of this mentored career development award is to provide a robust course of training in the biology of neurodegeneration and aging for Dr. Eteleeb, Ph.D., a candidate with extensive experience in genomics, omics, and machine learning, to enable his transition to rese...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD and related dementia><AD biological marker><AD biomarker><AD brain><AD dementia><AD pathway><AD patients><AD related biomarker><AD related dementia><AD therapy><AD treatment><AD-associated pathways><AD-related pathways><AD-specific pathways><ADRD><Address><Advisory Committees><Affect><Age><Aged 65 and Over><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease mechanism><Alzheimer disease treatment><Alzheimer pathway><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer treatment><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease Pathway><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease brain><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease therapeutic><Alzheimer's disease therapy><Alzheimer's mechanism><Alzheimer's patient><Alzheimer's related biomarker><Alzheimer's related pathways><Alzheimer's therapeutic><Alzheimer's therapy><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Animal Model><Animal Models and Related Studies><Autopsy><Award><Biological><Biological Markers><Biology><Blood><Blood Reticuloendothelial System><Brain><Brain Nervous System><Brain region><Cancers><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cerebrospinal Fluid><Chromatin Remodeling Complex><Chromatin Remodeling Factor><Clinical><Clinical Trials><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><DNA Methylation><Data><Data Set><Dedications><Degenerative Neurologic Disorders><Dementia><Dementia with Lewy Bodies><Development><Diagnosis><Disease><Disease Progression><Disorder><Disturbance in cognition><Doctor of Philosophy><Drugs><Educational workshop><Encapsulated><Encephalon><Environment><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Feedback><Foundations><Functional RNA><Funding><Future><Genes><Genetic><Genetic Markers><Genetic predisposing factor><Genomics><Goals><Heterogeneity><Human><Impaired cognition><Individual><Journals><K-Awards><K-Series Research Career Programs><Knowledge><Leadership><Learning><Machine Learning><Magazine><Malignant Neoplasms><Malignant Tumor><Medical Research><Medication><Mentors><Mentorship><Modality><Modeling><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><Multiomic Data><Nerve Degeneration><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurology><Neuron Degeneration><Neurosciences><Noncoding RNA><Nontranslated RNA><PD with dementia><Parkinson Disease dementia><Parkinson's Dementia><Parkinson's disease with dementia><Pathologic><Pathway interactions><Ph.D.><PhD><Pharmaceutical Preparations><Primary Senile Degenerative Dementia><Proteomics><Regulation><Reporting><Research><Research Career Program><Risk><Task Forces><Tauopathies><Techniques><Testing><Training><Training Programs><United States><Universities><Untranslated RNA><Validation><Washington><Work><Workshop><above age 65><advisory team><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><bio-markers><biologic><biologic marker><biological systems><biomarker><biomarker identification><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><blood-based biomarker><blood-based marker><brain atrophy><cerebral atrophy><cerebral spinal fluid><chromatin modifier><clinical relevance><clinically relevant><cognitive dysfunction><cognitive function><cognitive loss><cohort><conference><convention><cortical atrophy><data integration><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><dementia in PD><dementia in Parkinson disease><design><designing><developmental><digital><disease duration><disease length><disease subgroups><disease subtype><disorder subtype><drug/agent><effective therapy><effective treatment><epigenetically><experience><expression subtypes><gene biomarker><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic risk factor><histone modification><human old age (65+)><identification of biomarkers><identification of new biomarkers><illness length><improved><inherited factor><innovate><innovation><innovative><insight><machine based learning><malignancy><marker identification><mechanisms in AD><mechanisms in Alzheimer's disease><medical college><medical schools><model of animal><model organism><molecular biomarker><molecular marker><molecular profile><molecular signature><molecular sub-types><molecular subsets><molecular subtypes><mouse model><multiple data sets><multiple datasets><multiple omic data><murine model><necropsy><neoplasm/cancer><neural degeneration><neurodegeneration><neurodegenerative><neurodegenerative illness><neurological degeneration><neuronal degeneration><neuropathologic><neuropathologic tau><neuropathological><neuropathological tau><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><noncoding><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><over 65 years><pathway><pathways associated with AD><pathways associated with Alzheimer's><pathways contribute to Alzheimer's><pathways involved in Alzheimer disease><pathways that contribute to AD><pathways that drive AD><pathways underlying Alzheimer's><patient living with Alzheimer's disease><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><postmortem><potential biological marker><potential biomarker><precision medicine><precision-based medicine><primary degenerative dementia><school of medicine><senile dementia of the Alzheimer type><sex><skills><spatial and temporal><spatial temporal><spatiotemporal><specific biomarkers><spinal fluid><summit><symposia><symposium><tau associated neurodegeneration><tau associated neurodegenerative process><tau driven neurodegeneration><tau induced degeneration><tau induced neurodegeneration><tau mediated neurodegeneration><tau neurodegenerative disease><tau neuropathology><tau pathology><tau pathophysiology><tau proteinopathy><tau related neurodegeneration><tau-induced pathology><tauopathic neurodegenerative disorder><tauopathy><trait><transcriptomics><validations><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Heejong Kim

WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY

Exploratory lead · 30/100
Recent
Active award
Career award
$153,721
FY 2026

Project Title

Robust and Interpretable Multimodal Machine Learning Models for Diagnosis and Prognosis of Prostate Cancer

Grant Number:

5K25CA283145-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2029

Project Abstract

ABSTRACT Prostate cancer is the second leading cause of cancer death and affects about 13 out of 100 American men. The standard diagnosis approach for prostate cancer incorporates prostate specific- antigen (PSA) blood test, digital rectal examination and biopsy, and, recently, the Prostate Imaging ...

Research Terms

<Adopted><Affect><American male><American man><American men><Anatomic Sites><Anatomic structures><Anatomy><Architecture><Award><Base of Human Prostate><Base of the Prostate><Biochemical><Biology><Biopsy><Blood Tests><Cancer Biology><Cancer Cause><Cancer Etiology><Cancers><Cessation of life><Clinical><Clinical Evaluation><Clinical Management><Clinical Testing><Complement><Complement Proteins><Computing Methodologies><Counseling><Data><Data Set><Data Systems><Death><Detection><Development><Diagnosis><Digital Rectal Examination><EC 3.4.21.34><Engineering / Architecture><Ethnic Origin><Ethnicity><Evaluation><Family><Future><Genomics><Hematologic Tests><Hematological Tests><Hematology Testing><History><IT Systems><Image><Image Analyses><Image Analysis><Information Systems><Information Technology Systems><Investigators><Kallikrein 3><Knowledge><Label><Learning><Lesion><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Malignant Neoplasms><Malignant Tumor><Malignant neoplasm of prostate><Malignant prostatic tumor><Maps><Masks><Medical><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medicine><Mentorship><Methods><Modality><Modeling><Multimodal ML><Multimodal machine learning><NMR Imaging><NMR Tomography><Nomograms><Nuclear Magnetic Resonance Imaging><Oncology><Oncology Cancer><Outcome><P-30 Antigen><PSA level><PSA value><Pathology><Patients><Performance><Plasma Kallikrein Precursor><Plasma Prekallikrein><Prediction of Response to Therapy><Probability><Prognosis><Prostate><Prostate CA><Prostate Cancer><Prostate Gland><Prostate Specific Antigen Preproprotein><Prostate malignancy><Prostate-Specific Antigen><Prostatic Gland><Prostatovesiculectomy><Protocol><Protocols documentation><Quality Control><Race><Races><Radical Prostatectomy><Recording of previous events><Recurrence><Recurrent><Reporting><Research><Research Personnel><Researchers><Science><Selection for Treatments><Semenogelase><Seminin><Severities><Site><Staging><Structure of base of prostate><TCIA><Techniques><Test Result><The Cancer Imaging Archive><Training><Treatment outcome><U.S. Males><US Men><US male><Vendor><Zeugmatography><accurate diagnosis><big imaging data><cancer diagnosis><cancer imaging><cancer location><cancer site><clinical diagnosis><clinical predictors><clinical significance><clinical test><clinically significant><complementation><computational methodology><computational methods><computer based method><computer based prediction><computer methods><computing method><deep learning><deep learning based model><deep learning method><deep learning model><deep learning strategy><density><developmental><diagnosis standard><experience><gamma-Seminoprotein><hK3 Kallikrein><histories><image evaluation><image interpretation><imaging><imaging Segmentation><imaging in the prostate><improved><large imaging data><large-scale imaging data><machine based learning><machine learning based model><machine learning model><males in America><males in the U.S.><males in the US><males in the USA><males in the United States><malignancy><men in America><men in the U.S.><men in the US><men in the USA><men in the United States><multi-modal data><multi-modal datasets><multi-modality><multidisciplinary><multimodal data><multimodal datasets><multimodal learning><multimodality><multiparametric imaging><neoplasm/cancer><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><novel><oncologic imaging><oncology imaging><predict therapeutic response><predict therapy response><predictive modeling><programs><prostate imaging><prostate specific antigen level><prostate specific antigen value><racial><racial background><racial origin><radiologist><radiomics><research clinical testing><risk stratification><screening><screenings><selection of treatment><serum PSA><serum prostate specific antigen><skills><stratify risk><targeted imaging><therapy prediction><therapy selection><tool><treatment planning><treatment prediction><treatment response prediction><treatment selection><tumor imaging>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Heather Marie Shappell

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Exploratory lead · 30/100
Recent
Active award
Career award
$148,491
FY 2026

Project Title

Statistical Methods for Whole-Brain Dynamic Connectivity Analysis

Grant Number:

5K25EB032903-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/28/2027

Project Abstract

My objective for the K25 award is to establish myself as an independent neuroimaging statistician, with expertise in whole-brain network analyses and an integral member of multidisciplinary research teams devoted to addressing diseases of the brain. Attaining these goals will require didactic traini...

Research Terms

<AD dementia><Accounting><Address><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Artifacts><Award><Behavior><Biology><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain region><Brain scan><Career Counseling><Career Guidance><Clinical><Cognition><Communication><Complex><Computer software><Data><Data Analyses><Data Analysis><Data Collection><Dedications><Detection><Diagnosis><Education><Educational aspects><Educational workshop><Encephalon><Encephalon Diseases><Environment><Exhibits><Foundations><Functional MRI><Functional Magnetic Resonance Imaging><Future><Generalized Growth><Goals><Growth><Head><Human><Image><Image Analyses><Image Analysis><Individual><Interdisciplinary Research><Interdisciplinary Study><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Journals><Knowledge><Lead><Magazine><Medicine><Mentors><Methodology><Methods><Modeling><Modern Man><Morphologic artifacts><Motion><Multidisciplinary Collaboration><Multidisciplinary Research><Network Analysis><Neurologic><Neurological><Neurosciences><Occupational Guidance><Participant><Pathway Analysis><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Pb element><Population Research><Population-based research><Population-level research><Predisposition><Prevention><Primary Senile Degenerative Dementia><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Activity><Research Design><Research Grants><Research Project Grants><Research Projects><Scanning><Scientist><Series><Slide><Software><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Statistical Methods><Structure><Study Type><Susceptibility><System><Techniques><Time><Tissue Growth><Training><Training Activity><Training Programs><Variant><Variation><Vocational Counseling><Vocational Guidance><Work><Workshop><abnormal brain function><biomarker identification><brain dysfunction><brain impairment><career><career counselor><computational neuroscience><conference><convention><data interpretation><detection limit><dysfunctional brain><early biomarkers><early detection biomarkers><early detection markers><executive coaching><experiment><experimental research><experimental study><experiments><fMRI><fMRI scan><functional MRI scan><functional magnetic resonance imaging scan><heavy metal Pb><heavy metal lead><identification of biomarkers><identification of new biomarkers><image evaluation><image interpretation><imaging><improved><infancy><infantile><innovate><innovation><innovative><insight><interest><investigate population><marker identification><markov model><member><neural imaging><neuro-imaging><neuroimaging><neurological imaging><novel><ontogeny><patient oriented outcomes><population investigation><population level investigation><population specific research><primary degenerative dementia><response><senile dementia of the Alzheimer type><skills><statistic methods><statistical analysis><studies of populations><study design><study of the population><study population><summit><survey population><symposia><symposium><theories><tool><training module>
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Kushal Seetharam

HARVARD UNIVERSITY, CAMBRIDGE, MA

Exploratory lead · 30/100
Recent
Active award
Career award
$142,182
FY 2026

Project Title

Elucidating Biomolecular Dynamics using Magnetic Resonance Augmented by Machine Learning and Quantum Technologies

Grant Number:

1K25GM163098-01

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/10/2026

End Date:

1/31/2031

Project Abstract

PROJECT SUMMARY / ABSTRACT This proposal, “Elucidating biomolecular dynamics using magnetic resonance augmented by machine learning and quantum technologies” addresses the need for experimental methods to probe the dynamics of large biomolecules in near-physiological conditions in a straightforward ...

Research Terms

<Address><Advisory Committees><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Award><Benchmarking><Best Practice Analysis><Biochemistry><Biological><Biological Chemistry><Biological Function><Biological Process><Biology><Biophysics><Bypass><Cancers><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cellular biology><DF/HCC><Dana-Farber Cancer Institute><Data><Development><Diamond><Differential Algebraic Equation><Differential Equation><Engineering><Fluoroquinolones><Fourier Transform><Human><Intracellular Communication and Signaling><Investigators><Kinases><Label><Learning><Light><Machine Learning><Magnetic Resonance><Malignant Neoplasms><Malignant Tumor><Mentorship><Methodology><Methods><Miscellaneous Antibiotic><Modern Man><Molecular><Molecular Weight><Nitrogen><O element><O2 element><Oxygen><Phosphotransferase Gene><Phosphotransferases><Photoradiation><Physics><Physiologic><Physiologic pulse><Physiological><Policies><Position><Positioning Attribute><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Postdoc><Postdoctoral Fellow><Posttranslational Modifications><Posttranslational Protein Processing><Process><Protein Dynamics><Protein Modification><Proteins><Protocol><Protocols documentation><Pulse><Research><Research Associate><Research Personnel><Researchers><Resolution><Sampling><Science><Signal Transduction><Signal Transduction Systems><Signaling><System><Systems Biology><Task Forces><Techniques><Testing><Therapeutic><Training><Transphosphorylases><Universities><Validation><Work><advisory team><analysis pipeline><benchmark><biologic><biological signal transduction><biophysical foundation><biophysical principles><biophysical sciences><career><cell biology><cost><deep learning><deep learning based neural network><deep learning method><deep learning neural network><deep learning strategy><deep neural net><deep neural network><density><design><designing><developmental><experience><experiment><experimental research><experimental study><experiments><innovate><innovation><innovative><interest><machine based learning><malignancy><nano meter scale><nano meter sized><nanometer scale><nanometer sized><nanoscale><neoplasm/cancer><neural><neural network><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutics><novel therapy><phototropin><post-doc><post-doctoral><post-doctoral trainee><quantum><quantum coding><quantum computation><quantum computer><quantum computing><quantum error correcting codes><quantum sensing><quantum technologies><research associates><resolutions><simulation><single molecule><statistical learning><theories><validations><voltage>
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Mohsen Bahrami

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Exploratory lead · 30/100
Recent
Active award
Career award
$136,244
FY 2026

Project Title

Cerebral Small Vessel Disease and Dementia: Defining Global Resilience and Disruption in Brain Networks

Grant Number:

5K25AG090707-02

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

11/15/2024

End Date:

10/31/2029

Project Abstract

My goal is to establish myself as an independent biomedical researcher in brain aging and Alzheimer’s disease (AD) and AD related dementias (ADRD). My passion to build a career in aging stems from my profound desire to help older people to maintain their functionality and quality of life. AD/ADRD ar...

Research Terms

<AD and related dementia><AD biological marker><AD biomarker><AD dementia><AD pathology><AD patients><AD related biomarker><AD related dementia><AD risk><AD risk factor><ADRD><Activities of Daily Living><Activities of everyday life><Address><Affect><Age related pathologies><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease patient><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's pathology><Alzheimer's patient><Alzheimer's related biomarker><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Anatomic Sites><Anatomic structures><Anatomy><Autopsy><Award><Biological Markers><Biological Testing><Blood Vessels><Brain><Brain Nervous System><Brain scan><Capsicum><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cerebral small vessel disease><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complex><Computer Software Tools><Computer software><Coupling><Data><Data Set><Dementia><Detection><Diagnostic><Diffuse><Disturbance in cognition><Educational workshop><Elderly><Encephalon><Environment><Foundations><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Future><Goals><Grant><Health><Impaired cognition><Investigators><K-Awards><K-Series Research Career Programs><Knowledge><Lead><Lesion><Licensing><Lobar><Location><Machine Learning><Mentors><Methodology><Methods><Microvascular Dysfunction><Modeling><Multi-Ethnic Study of Atherosclerosis><NIH><National Institutes of Health><Nature><Neurosciences><Older Population><Outcome><Pathologic><Pathology><Pb element><Prevalence><Primary Senile Degenerative Dementia><Principal Investigator><Probability><QOL><Quality of life><Reproducibility><Research><Research Career Program><Research Personnel><Researchers><Risk Factors><Software><Software Tools><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Structure><Testing><Time><Training><United States National Institutes of Health><Work><Workshop><Writing><aberrant aging><abnormal aging><advanced age><age associated disease><age associated disorder><age associated impairment><age associated pathologies><age dependent disease><age dependent disorder><age dependent impairment><age dependent pathologies><age induced pathologies><age related human disease><age-related disease><age-related disorder><age-related impairment><aged brain><aging associated pathologies><aging brain><aging dependent pathologies><aging induced pathologies><aging pathologies><aging process><aging related pathologies><alzheimer risk><bio-markers><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><brain MR imaging><brain MRI><brain health><brain magnetic resonance imaging><career><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral microbleeds><cerebral microhemorrhage><cerebral small vessel disorder><cerebrovascular contributions to Alzheimer's disease><cerebrovascular dysfunction in Alzheimer's disease><cognitive assessment><cognitive dysfunction><cognitive loss><cognitive testing><conference><convention><daily living function><daily living functionality><deep learning><deep learning method><deep learning strategy><develop software><developing computer software><diagnostic tool><dysfunctional age related change><dysfunctional aging><fMRI><functional ability><functional capacity><geriatric><healthy aging><healthy human aging><heavy metal Pb><heavy metal lead><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><impaired aging><improved><insight><machine based learning><machine learning based method><machine learning based model><machine learning method><machine learning methodologies><machine learning model><maladaptive aging><malleable risk><medical college><medical schools><microvascular complications><microvascular disease><modifiable risk><multidisciplinary><necropsy><network models><neuropathologic><neuropathological><neuropathology><novel><older adult><older adulthood><older groups><older individuals><older person><pathological age related changes><pathological aging><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><pepper><postmortem><pre-clinical><preclinical><preservation><primary degenerative dementia><resilience><resilient><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><school of medicine><senile dementia of the Alzheimer type><senior citizen><skills><small vessel disease><software development><software toolkit><statistical analysis><statistics><stem><summit><symposia><symposium><tool><training opportunity><translational study><vascular><vascular burden on Alzheimer's disease><vascular contribution to Alzheimer's Disease><vascular contributions><vascular contributions to AD><vascular contributions to Alzheimer's><vascular contributor to Alzheimer's disease><vascular dysfunction in AD><vascular dysfunction in Alzheimer's disease><work-study>
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MARGARET H ZELLER

UNIVERSITY OF CINCINNATI, CINCINNATI, OH

Exploratory lead · 26/100
Above-average budget
Career award
$830,307
FY 2024

Project Title

KL2 Training Program

Grant Number:

5KL2TR001426-09

Activity Code:

KL2

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/14/2015

End Date:

9/30/2025

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

The University of Cincinnati Center for Clinical and Translational Science and Training (CCTST) has an excellent record of accomplishment in training KL2 Scholars. The KL2 program has appointed 24 Scholars (50% women, 12.5% underrepresented) from diverse disciplines since 2009 (2 per year, for 2- to...

Research Terms

<3-D><3-Dimensional><3D><Active Learning><Address><American Heart Association><Appointment><Award><Biomedical Research><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Clinical><Clinical Investigator><Clinical Research><Clinical Sciences><Clinical Study><Collaborations><Communication><Communities><Cooperative Learning><Decrease disparity><Department of Defense><Dimensions><Direct Costs><Discipline><Educational workshop><Ensure><Ethnic Origin><Ethnicity><Experiential Learning><Faculty><Fostering><Funding><Future><Gender><Goals><Grant><Health><Health system><Industry><Institution><International><Investigators><Journals><K-Awards><K-Series Research Career Programs><Leadership><Learning><Lower disparity><Magazine><Manuscripts><Measures><Mentors><NCATS><National Center for Advancing Translational Sciences><Outcome><Pathway interactions><Position><Positioning Attribute><Principal Investigator><Program Development><Program Evaluation><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><Race><Races><Research><Research Career Program><Research Ethics><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Researchers><Scholars Program><Science><Secure><Sight><Site><Sum><Training><Training Programs><Translational Research><Translational Science><Translations><Universities><Vision><Woman><Work><Workshop><burn-out><burnout><career><career development><clinical center><design><designing><disparity reduction><evidence base><experience><health outcome disparity><health outcome inequality><health outcome inequity><improved><inequitable health outcome><innovate><innovation><innovative><life span><lifespan><meeting><meetings><method development><mitigate disparity><multidisciplinary><next generation><pathway><population health><programs><racial><racial background><racial origin><recruit><reduce disparity><reduction in disparity><research and methods><scale up><skill acquisition><skill development><skills><success><three dimensional><translation><translation research><translational investigation><translational investigator><translational researcher><translational scientist><unequal health outcome><visual function><workforce needs>
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Arthur Sherman

NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES

Exploratory lead · 24/100
Large award
$1,143,753
FY 2025

Project Title

Modeling Pathogenesis of Type 2 Diabetes

Grant Number:

1ZIADK075137-10

Activity Code:

ZIA

Mechanism:

Intramural Research

Agency:

NIH

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

In previous reports we have described our model for T2D pathogenesis. It builds on the foundational model of Topp et al (J. Theor. Biol. 2000; 206(4):605-19), which posited that moderate but persistent increases (i.e., not daily fluctuations) in blood sugar mediate negative feedback to increase ins...

Research Terms

<12-20 years old><Acceleration><Adolescence><Adopted><Adult-Onset Diabetes Mellitus><Agreement><Antidiabetic Hormone><Apoptosis><Apoptosis Pathway><Area><Attention><Autoregulation><Behavior><Beta Cell><Blood Glucose><Blood Plasma><Blood Sugar><Caloric Restriction><Causality><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Chronic><Clinical Research><Clinical Study><Compensation><D-Glucose><Data><Deterioration><Development><Dextrose><Diabetes Mellitus><Diagnosis><Diagnostic><Disease><Disorder><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Etiology><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Feedback><Fostering><Genetic study><Glucagon><Glucose><Glucose Clamp><Glukagon><Goals><HG-Factor><Homeostasis><Hour><Human><Humulin R><Hyperglycemia><Hyperglycemic-Glycogenolytic Factor><Hyperinsulinemia><Hyperinsulinemic Clamp><Hyperinsulinism><IVGTT><Individual><Infusion><Infusion procedures><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><International><Intervention><Ketosis-Resistant Diabetes Mellitus><Koreans><Liver><Math Models><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Modeling><Modern Man><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><OGTT><Obesity><Onset of illness><Oral Glucose Tolerance Test><Pancreatic beta Cell><Pancreatic β-Cell><Paper><Pathogenesis><Pathway interactions><Persons><Physiological Homeostasis><Plasma><Plasma Serum><Play><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Prevention><Process><Programmed Cell Death><Public Health><Regular Insulin><Regulation><Reporting><Resistance><Resolution><Reticuloendothelial System, Serum, Plasma><Rodent><Rodentia><Rodents Mammals><Role><Sampling><Scheme><Slow-Onset Diabetes Mellitus><Source><Stable Diabetes Mellitus><Staging><Standard Model><Structure of beta Cell of islet><Subcellular Process><T2 DM><T2D><T2DM><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Work><adiposity><adolescence (12-20)><adult onset diabetes><bariatric surgery><base><bases><blood glucose regulation><calorie restriction><causation><cohort><corpulence><cost><cost effective><design><designing><developmental><diabetes><diabetes pathogenesis><diagnostic criteria><disease causation><disease model><disease onset><disorder model><disorder onset><epidemiologic investigation><epidemiology study><ethnic subgroup><ethnicity group><experience><fasting glucose><gastric banding><gastric bypass surgery><glucose RA><glucose control><glucose homeostasis><glucose production><glucose rate of appearance><glucose regulation><glucose tolerance><hepatic body system><hepatic organ system><hyperglucagonemia><hyperglycemic><implantable gastric stimulation banding><infusions><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><intravenous glucose tolerance><intravenous glucose tolerance test><ketosis resistant diabetes><mathematic model><mathematical model><mathematical modeling><maturity onset diabetes><obesity surgery><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathway><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><resistant><resolutions><response><screening><screenings><social role><stomach stapling><type 2 DM><type II DM><type two diabetes><weight loss surgery><β-cell><β-cells><βCell>
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Mohamed A Ghanem

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Exploratory lead · 24/100
Active award
Career award
$191,624
FY 2026

Project Title

Noninvasive Repositioning of Kidney Stone Fragments with Acoustic Forceps

Grant Number:

5K25DK132416-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/11/2023

End Date:

11/30/2027

Project Abstract

Project Summary/Abstract Kidney stones are prevalent and one of the costliest urologic diseases. The available treatment options such as ureteroscopy or shockwave wave lithotripsy break the stone into small fragments that can lead to future growth and recurrence of symptoms. This proposal investiga...

Research Terms

<2-dimensional><3-D><3-Dimensional><3D><Acoustics><Address><Affect><Algorithms><American><Applications Grants><Award><Back><Bladder><Bladder Urinary System><Body Tissues><Cell Communication and Signaling><Cell Signaling><Circulatory Collapse><Clinical Trials><Collaborations><Complex><Control Groups><Cutaneous><Data><Deposit><Deposition><Devices><Dorsum><ED visit><ER visit><Educational workshop><Elements><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Event><Family suidae><Feedback><Forcep><Frequencies><Funding><Future><Generalized Growth><Geometry><Glass><Goals><Grant Proposals><Growth><Heterogeneity><Histologic><Histologically><Hospital Admission><Hospitalization><Human><Image><Implant><In Vitro><Injury><Intervention><Intracellular Communication and Signaling><Investigation><Investigators><Kidney><Kidney Calculi><Kidney Pelvis><Kidney Stones><Kidney Urinary System><Knowledge><Laboratories><Length><Litholapaxy><Lithotripsy><Measurement><Measures><Mechanics><Mentors><Methods><Modeling><Modern Man><Motion><Operative Procedures><Operative Surgical Procedures><Patients><Pelvic><Pelvic Region><Pelvis><Phase><Physics><Physiologic pulse><Pigs><Position><Positioning Attribute><Protocol><Protocols documentation><Pulse><Radiation><Recurrence><Recurrent><Renal Calculi><Renal Stone><Renal pelvis><Research><Research Personnel><Research Proposals><Researchers><Residual><Residual state><Rotation><Safety><Shapes><Shock><Signal Transduction><Signal Transduction Systems><Signaling><Suidae><Supersonic waves><Surface><Surgical><Surgical Interventions><Surgical Procedure><Swine><Symptoms><System><Techniques><Technology><Testing><Time><Tissue Growth><Tissues><Transducers><Translational Research><Translational Science><Ultrasonic><Ultrasonic wave><Ultrasonics><Ultrasound waves><Ureter><Ureteroscopy><Urinary Tract Diseases><Urinary tract><Urine><Urologic Diseases><Urologic Disorder><Urological Diseases><Urological Disorders><Visualization><Workshop><alleviate symptom><ameliorating symptom><arm><biological signal transduction><career><career development><circulatory shock><clinical implementation><common treatment><computer based prediction><conference><convention><cost><decrease symptom><determine efficacy><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><fewer symptoms><imaging><improved><in vivo><indexing><industrial partnership><industry partner><industry partnership><injuries><injury to tissue><intervention arm><mechanic><mechanical><new approaches><novel approaches><novel strategies><novel strategy><object shape><ontogeny><particle><pig model><piglet model><porcine><porcine model><predictive modeling><pressure><randomized control study><randomized, controlled study><reduce symptoms><relieves symptoms><renal><responsible research conduct><shocks><success><suid><summit><surgery><swine model><symposia><symposium><symptom alleviation><symptom reduction><symptom relief><tech development><technology development><three dimensional><tissue injury><tissue phantom><translation research><translational investigation><treatment arm><two-dimensional><ultrasound><urinary bladder><urinary tract disorder>
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Giulia Menichetti

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Exploratory lead · 24/100
Active award
Career award
$163,485
FY 2026

Project Title

Methods for Unraveling the Impact of Dietary Xenobiotics on COPD Exacerbations with Multi-Dimensional Networks

Grant Number:

5K25HL173665-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2029

Project Abstract

PROJECT SUMMARY/ABSTRACT Chronic obstructive pulmonary disease (COPD) is projected to become the third leading cause of death globally by 2030. While smoking is a primary risk factor, a growing body of epidemiological research points to the role of nutrition in modulating the risk for COPD and COPD-...

Research Terms

<Acute><Address><Adherence><Agreement><Algorithms><Automobile Driving><Award><Biochemical Reaction><Biological Function><Biological Process><Biology><Biomedical Research><Blood Plasma><COPD><Cause of Death><Chemicals><Chronic Obstruction Pulmonary Disease><Chronic Obstructive Lung Disease><Chronic Obstructive Pulmonary Disease><Classification><Clinical><Cohort Studies><Complex><Data><Development><Developmental Process><Diathesis><Diet><Dietary Component><Dietary Intervention><Dietary Practices><Digestion><Dimensions><Disease><Disease susceptibility><Disorder><Economic Income><Economical Income><Ensure><Environmental Exposure><Enzymatic Reaction><Epidemiologic Research><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Food><Food Access><Foundations><Frequencies><Goals><Hereditary><Human><Income><Individual><Inflammatory><Inherited><Intake><Intermediary Metabolism><Intervention><Investigators><Knowledge><Learning><Link><Lung Diseases><Machine Learning><Mediterranean Diet><Mentors><Metabolic Processes><Metabolism><Methodology><Methods><Minority><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><Multiomic Data><N-3 polyunsaturated fatty acid><Neighborhoods><Nested Case-Control Study><Network-based><Nutrition><Nutrition Interventions><Nutritional Interventions><Omega-3 Fatty Acids><Omega-3 PUFA><Omega-3 Polyunsaturated Fatty Acid><Outcome><Participant><Pathogenesis><Pathway interactions><Phenotype><Plants><Plasma><Plasma Serum><Pneumology><Pneumonology><Predisposition><Process><Prospective cohort><Proteins><Proteomics><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Medicine><Pulmonology><Randomization trial><Research><Research Design><Research Personnel><Researchers><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Role><Science><Severities><Smoker><Smoking><Smoking History><Study Type><Susceptibility><Systematics><Techniques><Testing><Training><Transport Reaction><Xenobiotics><absorption><analyzing longitudinal><career><chronic obstructive pulmonary disorder><cigarette smoking><cigarette use><clinical practice><clinical training><cohort research study><cohort survey><combustible cigarette><conventional cigarette><deep learning based model><deep learning model><design><designing><developmental><diet intervention><dietary><dietary approach><dietary pattern><diets><disease of the lung><disorder of the lung><driving><endophenotype><epidemiologic investigation><epigenetically><ex-smoker><experience><exposure to environmental agents><exposure to environmental factors><exposure to environmental stimuli><exposure to environmental substances><former smoker><incomes><insight><investigate epidemiology><learning activity><learning algorithm><learning method><learning strategies><learning strategy><liability to disease><longitudinal analysis><lung disorder><machine based learning><metabolism measurement><metabolomics><metabonomics><microbiome><molecular profile><molecular signature><mortality><multiomics><multiple omic data><multiple omics><n-3 Fatty Acids><n-3 PUFA><novel><nutritional approach><omega-3><omega-3s><pack/year><panomics><pathway><pharmacologic><precision nutrition><predictive signature><prospective><protein protein interaction><pulmonary><randomized trial><secondary metabolite><sex><skills><small molecule><social role><stem><study design><study epidemiology><survey epidemiology><theories><traditional cigarette><trait><transcriptomics>
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Aprinda Indahlastari Queen

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Exploratory lead · 24/100
Active award
Career award
$147,334
FY 2026

Project Title

Resubmission: A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients

Grant Number:

5K25AG086592-02

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/9/2024

End Date:

11/30/2029

Project Abstract

Project Summary/Abstract This K25 proposal is for a five-year mentored training program to launch Dr. Aprinda Indahlastari’s career as an independent aging investigator by leveraging her engineering background to develop personalized cognitive intervention in NIH-relevant research on cognitive aging...

Research Terms

<AD and related dementia><AD dementia><AD related dementia><ADRD><Activities of Daily Living><Activities of everyday life><Acute><Address><Affect><Age><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Anatomic Sites><Anatomic structures><Anatomy><Atrophic><Atrophy><Automobile Driving><Back><Behavioral><Biological Markers><Brain><Brain Nervous System><Brain region><CNS plasticity><Cathodes><Cell Communication and Signaling><Cell Signaling><Characteristics><Clinical><Clinical Treatment><Clinical Trials><Clinical Trials Design><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive aging><Cognitive decline><Cognitive function abnormal><Complex><Computer Models><Computerized Models><Cross-Over Designs><Crossover Design><Custom><Dementia><Disturbance in cognition><Dorsum><Dose><Electrodes><Encephalon><Engineering><Enrollment><Florida><Formulation><Future><Generalized Growth><Glutamates><Grant><Growth><Human><Immediate Memory><Impaired cognition><Impairment><Individual><Intervention><Intervention Strategies><Intervention Studies><Intracellular Communication and Signaling><Investigators><Knowledge acquisition><L-Glutamate><Lead><Learning Skill><Machine Learning><Memory><Memory Loss><Mentors><Mentorship><Methods><Modeling><Modern Man><Multimodal ML><Multimodal machine learning><NIH><National Institutes of Health><Neurobiology><Neuronal Plasticity><Neurosciences Research><Outcome><Outcome Measure><Participant><Patients><Pb element><Performance><Persons><Population><Prefrontal Cortex><Primary Senile Degenerative Dementia><Property><QOL><QOL improvement><Quality of life><Research><Research Personnel><Research Proposals><Researchers><Scalp><Scalp structure><Short-Term Memory><Signal Transduction><Signal Transduction Systems><Signaling><Tissue Growth><Training><Training Programs><Treatment outcome><United States National Institutes of Health><Universities><Variant><Variation><White Matter Hyperintensity><age associated><age correlated><age dependent><age linked><age related><age specific><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><bio-markers><biologic marker><biological signal transduction><biomarker><blood oxygen level dependent><blood oxygenation level dependent><brain atrophy><career><career development><central nervous system plasticity><cerebral atrophy><clinical effect><clinical intervention><clinical therapy><cognitive ability><cognitive change><cognitive dysfunction><cognitive loss><cognitive task><cohort><combat><computational modeling><computational models><computational studies><computer based models><computer studies><computerized modeling><conference><convention><cortical atrophy><customs><daily living function><daily living functionality><driving><effective intervention><enroll><experience><functional ability><functional capacity><glutamatergic><heavy metal Pb><heavy metal lead><high risk><improved><improvements in QOL><improvements in quality of life><information gathering><interest><intervention effect><intervention research><interventional research><interventional study><interventions research><machine based learning><machine learned algorithm><machine learning algorithm><machine learning based algorithm><measurable outcome><memory decline><mild cognitive decline><mild cognitive disorder><mild cognitive dysfunction><mild cognitive impairment><mild cognitive loss><mild neurocognitive impairment><multi-modal neuro-imaging><multimodal learning><multimodal neuroimaging><neural imaging><neural network><neural plasticity><neuro-imaging><neurobiological><neuroimaging><neurological imaging><neuroplastic><neuroplasticity><older adult><older adulthood><ontogeny><outcome measurement><personalized health intervention><personalized intervention><population aging><precision interventions><primary degenerative dementia><primary outcome><quality of life improvement><response><senile dementia of the Alzheimer type><summit><supervised learning><supervised machine learning><symposia><symposium><transcranial direct current stimulation><trial regimen><trial treatment><working memory>
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Fatemeh Adelnia

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

Exploratory lead · 24/100
Active award
Career award
$75,600
FY 2026

Project Title

Development and Application of T1rho Dispersion Imaging of Aging Muscle

Grant Number:

3K25AG076864-04S1

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

5/31/2027

Project Abstract

Project Summary This administrative supplement is requested to support research continuity and retention of the scientific aims outlined in a K25 NIAAward #1K25AG076864, titled "Development and Application of T1rho Dispersion Imaging of Aging Muscle." The principal investigator is currently managing...

Research Terms

<15 year old><15 years of age><21+ years old><3-D><3-Dimensional><3D><6 year old><6 years of age><Academic Medical Centers><Administrative Supplement><Adult><Adult Human><Affect><Aging><Anatomic Sites><Anatomic structures><Anatomy><Animal Model><Animal Models and Related Studies><Animals><Biological><Biological Markers><Blood Vessels><Blood Volume><Blood capillaries><Body Tissues><Capillarity><Causality><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell-Extracellular Matrix><Cells><Childbirth><Chronic Disease><Chronic Illness><Clinical><Clinical Evaluation><Clinical Research><Clinical Study><Clinical Testing><Clinical assessments><Collaborations><Collagen><Computer Analysis><Data><Deposit><Deposition><Deterioration><Development><ECM><Ensure><Etiology><Event><Extracellular Matrix><F344 Rats><Fats><Fatty acid glycerol esters><Fibrosis><Fischer Rats><Frequencies><Functional impairment><Goals><Grant><High-Risk Pregnancy><Histologic><Histologically><Histology><Human><Hydrogen Oxide><Image><Imaging Procedures><Imaging Technics><Imaging Techniques><Impairment><Inbred CDF Rats><Inbred F344 Rats><Inbred Fischer 344 Rats><Inbred Fisher 344 Rats><Intracellular Communication and Signaling><Knowledge><Life><Longitudinal Studies><Longitudinal Surveys><MR Imaging><MR Tomography><MRI><MRI biomarker><MRI marker><MRIs><Magnetic Resonance Imaging><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Membrane><Metabolic><Methods><Modern Man><Muscle><Muscle Atrophy><Muscle Cell Contraction><Muscle Contraction><Muscle Fibers><Muscle Tissue><Muscular Atrophy><Muscular Contraction><Myotubes><NMR Imaging><NMR Tomography><Noise><Nuclear Magnetic Resonance Imaging><Nutrient><O element><O2 element><Oxygen><Pathologic><Pathology><Patient Self-Report><Physical activity><Principal Investigator><Productivity><Protocol><Protocols documentation><Relaxation><Research><Research Activity><Research Assistant><Research Support><Resolution><Resource Sharing><Rest><Rhabdomyocyte><Role><Rotation><Scanning><Schedule><Self-Report><Signal Transduction><Signal Transduction Systems><Signaling><Skeletal Fiber><Skeletal Muscle><Skeletal Muscle Cell><Skeletal Muscle Fiber><Skeletal Myocytes><Structure><Surrogate Markers><Techniques><Therapeutic><Thigh><Thigh structure><Time><Tissues><Training><Translating><University Medical Centers><Visit><Voluntary Muscle><Water><Zeugmatography><adulthood><age 15><age 15 years><age 6><age 6 years><age associated><age associated chronic condition><age associated chronic disease><age associated chronic disorder><age associated chronic health condition><age associated chronic illness><age correlated><age dependent><age group><age linked><age related><age related chronic condition><age related chronic disease><age related chronic disorder><age related chronic health condition><age related chronic illness><age specific><aged animal><aged animals><aged muscle><aging of muscle><animal old age><bio-markers><biologic><biologic marker><biological signal transduction><biomarker><capillary><causation><child birth><chronic disorder><clinical applicability><clinical application><clinical test><computational analyses><computational analysis><computer analyses><cost effective><developmental><diffusion weighted><digital><digital pathology><disability><disease causation><elderly animal><fifteen year old><fifteen years of age><frailty><healthy aging><healthy human aging><hemodynamics><human imaging><image-based method><imaging><imaging biomarker><imaging marker><imaging method><imaging modality><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><indexing><innovate><innovation><innovative><interest><juvenile animal><long-term study><longitudinal outcome studies><longitudinal research study><macromolecule><magnetic resonance imaging biomarker><magnetic resonance imaging marker><membrane structure><microvascular pathology><mid life><mid-life><middle age><middle aged><midlife><mitochondrial dysfunction><model of animal><muscle aging><muscle breakdown><muscle degradation><muscle deterioration><muscle loss><muscle wasting><muscular><new approaches><novel><novel approaches><novel strategies><novel strategy><old animals><parametric imaging><parent grant><protein distribution><quadriceps><quadriceps muscle><recruit><research clinical testing><resolutions><sarcopenia><sarcopenic><simulation><six year old><six years of age><social role><success><surrogate bio-markers><surrogate biomarkers><three dimensional><time interval><tool><vascular><volunteer><walking pace><walking speed><young animal>
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Marmar Moussa

UNIVERSITY OF OKLAHOMA, NORMAN, OK

Exploratory lead · 18/100
Active award
Career award
$198,721
FY 2025

Project Title

Computational approaches to the mechanistic elucidation of the serrated pathway of human colon carcinogenesis

Grant Number:

5K25CA270079-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/1/2023

End Date:

7/31/2028

Project Abstract

PROJECT SUMMARY This K25 Mentored Quantitative Research Development Award project proposal is to allow the PI, Dr. Marmar Moussa - an experienced Computer Scientist and Bioinformatician - to obtain additional training in cancer genomics and cellular and molecular cancer biology needed to lead an int...

Research Terms

<ATAC sequencing><ATAC-seq><ATACseq><Abscission><Anatomic Sites><Anatomic structures><Anatomy><Appearance><Area><Assay for Transposase-Accessible Chromatin using sequencing><Atlases><Award><Biopsy><CRC prevention><Cancer Biology><Cancer Induction><Cancerous><Cancers><Carcinoma><Cause of Death><Cell Body><Cell Communication><Cell Interaction><Cell-to-Cell Interaction><Cells><Characteristics><Chromosomal Instability><Chromosome Instability><Clinical><Clinical Markers><Collection><Colon><Colon Cancer><Colon Carcinoma><Colonic Polyps><Colorectal Cancer><Complex><Computing Methodologies><Connecticut><DNA mutation><Data><Detection><Development Plans><Development and Research><Diagnosis><Dysplasia><Early Diagnosis><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Epithelial cancer><Evolution><Excision><Extirpation><Formalin><Freezing><Gene Expression><Genes><Genetic Change><Genetic defect><Genetic mutation><Genomics><Goals><Heterogeneity><High grade dysplasia><Histologic><Histologically><Histology><Histopathology><Human><Hyperplasia><Hyperplastic><Immune Cell Activation><Immune infiltrates><Individual><Institution><Interdisciplinary Research><Interdisciplinary Study><Investigators><Lead><Lesion><Ligands><Link><MLH1><MLH1 gene><Malignant><Malignant - descriptor><Malignant Epithelial Neoplasms><Malignant Epithelial Tumors><Malignant Neoplasms><Malignant Tumor><Maps><Measures><Mentors><Methylation><Microsatellite Instability><Modeling><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><Morphology><Multidisciplinary Collaboration><Multidisciplinary Research><MutL E Coli Homolog 1><MutL E. Coli Homolog 1><Mutation><Neighborhoods><Normal Tissue><Normal tissue morphology><Oncogenesis><PLYPCMY><Paraffin Embedding><Pathology><Pathway interactions><Patients><Pattern><Pb element><Phenotype><Physicians><Polypectomy><Polyps><Position><Positioning Attribute><Precancerous Conditions><Premalignant Condition><Premalignant State><Prevention><Prevention program><Public Health><Publishing><R & D><R&D><Receptor Protein><Registries><Removal><Research><Research Personnel><Research Specimen><Researchers><Resolution><Risk><Sampling><Scientist><Series><Single cell seq><Specimen><Surgical Removal><System><Testing><Tissue Sample><Training><United States><Universities><Work><adenoma><assay for transposase accessible chromatin followed by sequencing><assay for transposase accessible chromatin seq><assay for transposase accessible chromatin sequencing><assay for transposase-accessible chromatin with sequencing><cancer genomics><cancer in the colon><cancer invasiveness><cancer microenvironment><carcinogenesis><career><career development><cell community><cellular community><clinical biomarkers><clinically useful biomarkers><cohort><colon cancer prevention><colon carcinogenesis><colon polyp><colorectal cancer prevention><colorectal carcinogenesis><computational methodology><computational methods><computer based method><computer methods><computer scientist><computing method><dyscrasia><early detection><epigenetically><epithelial carcinoma><exome><experience><genome mutation><heavy metal Pb><heavy metal lead><human data><immune activation><immune cell infiltrate><immune microenvironment><immunosuppressive microenvironment><immunosuppressive tumor microenvironment><improved><machine learning based model><machine learning model><malignancy><molecular profile><molecular signature><multiomics><multiple omics><neoplasm/cancer><novel><oncogenomics><panomics><pathway><precancer><precancerous><precancerous state><premalignant><prevent colon cancer><prevent colorectal cancer><receptor><research and development><resection><resolutions><single cell analysis><single cell next generation sequencing><single cell sequencing><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><tool><transcriptome profiling><transcriptomic profiling><transcriptomics><tumor><tumor immune microenvironment><tumor microenvironment><tumor-immune system interactions><tumorigenesis>
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Sangyeon Cho

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 18/100
Active award
Career award
$195,240
FY 2025

Project Title

Correlating Genotype and Phenotype of Metastatic Cancer Cells In Vivo Using Nanolaser Optical Barcode

Grant Number:

1K25CA301033-01

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/17/2025

End Date:

8/31/2030

Project Abstract

Project Summary. The complex dynamics of metastatic cancer, which include processes like plasticity, immune evasion, and therapy resistance, pose significant challenges to effective treatment. While emerging single-cell sequencing technologies now aid in understanding the genetic heterogeneity and c...

Research Terms

<4T1><Abdominal Cavity><Address><Advisory Committees><Affect><Assay><Bar Codes><Behavior><Behavioral><Bioassay><Biological Assay><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><Breast Cancer Cell><Breast Cancer Model><Breast Cancer Treatment><Breast tumor model><CD8><CD8B><CD8B1><CD8B1 gene><Cancers><Cavitas abdominis><Cell Body><Cell Communication><Cell Interaction><Cell Isolation><Cell Locomotion><Cell Migration><Cell Migration Assay><Cell Movement><Cell Segregation><Cell Separation><Cell Separation Technology><Cell division><Cell model><Cell-to-Cell Interaction><Cells><Cellular Assay><Cellular Migration><Cellular Motility><Cellular model><Chemistry><Clonality><Co-culture><Cocultivation><Coculture><Coculture Techniques><Color><Complex><Comprehension><Computer Analysis><Cristobalite><Cytoplasm><DNA><DNA seq><DNA sequencing><DNAseq><Data><Deoxyribonucleic Acid><Diameter><Dimensions><Disseminated Malignant Neoplasm><Drug resistance><Ensure><Epithelium><Fats><Fatty acid glycerol esters><Fellowship><Fluorescence><Gene Expression><Genetic><Genetic Heterogeneity><Genome><Genotype><Goals><Heterogeneity><Image><Imaging technology><Immune><Immune Evasion><Immune mediated therapy><Immunes><Immunologically Directed Therapy><Immunotherapy><Individual><LYT3><Laser Electromagnetic><Laser Radiation><Lasers><Length><Link><Liver><Location><Lung><Lung Respiratory System><Lymph Node Reticuloendothelial System><Lymph node proper><Lymphatic nodes><Malignant Cell><Malignant Neoplasms><Malignant Tumor><Measures><Mentors><Mesenchymal><Metastasis><Metastasize><Metastatic Cancer><Metastatic Lesion><Metastatic Malignant Neoplasm><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Metastatic breast cancer><Methods><Mice><Mice Mammals><Microscopy><Migration Assay><Modeling><Molecular Fingerprinting><Molecular Profiling><Monitor><Movement><Murine><Mus><Neoplasm Metastasis><Oncology><Oncology Cancer><Optics><Outcome><Phase><Phenotype><Position><Positioning Attribute><Principal Investigator><Process><Regulation><Research><Resistance><Resolution><Sand><Secondary Neoplasm><Secondary Tumor><Semiconductors><Shapes><Silica><Silicon Dioxide><Single cell seq><Site><T-Cells><T-Lymphocyte><Task Forces><Techniques><Technology><Time><Tissues><Training><Transcript><Treatment outcome><Tridymite><Triplet Multiple Birth><Triplets><Visualization><advisory team><anti-cancer research><barcode><behavior phenotype><behavioral phenotyping><biocompatibility><biomaterial compatibility><body movement><breast tumor cell><cancer cell><cancer metastasis><cancer microenvironment><cancer research><career><cell assay><cell behavior><cell motility><cell sorting><cellular behavior><computational analyses><computational analysis><computer analyses><design><designing><drug resistant><effective therapy><effective treatment><empowerment><global gene expression><global transcription profile><hepatic body system><hepatic organ system><high dimensional data><high dimensionality><imaging><immune evasive><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><improved><in vivo><in vivo Model><innovate><innovation><innovative><insight><live cell image><live cell imaging><live cell microscopy><live cellular image><live cellular imaging><lymph gland><lymph nodes><lymphnodes><mRNA sequencing><mRNA-seq><mRNAseq><malignancy><mammary><mammary cancer model><mammary tumor model><metastatic breast tumor><metastatic mammary cancer><metastatic mammary tumor><meter><migration><molecular imaging><molecular profile><molecular signature><molecule imaging><mouse model><multidimensional data><multidimensional datasets><murine model><nano-photonic><nanophotonic><neoplasm/cancer><novel><optical><particle><preservation><protein expression><resistance to Drug><resistance to therapy><resistant><resistant to Drug><resistant to therapy><resolutions><response to therapy><response to treatment><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell analysis><single cell expression profiling><single cell next generation sequencing><single cell sequencing><single cell transcriptomic profiling><single-cell RNA sequencing><spatial and temporal><spatial temporal><spatiotemporal><technology implementation><technology validation><therapeutic resistance><therapeutic response><therapy resistant><therapy response><thymus derived lymphocyte><tool><trait><transcriptome><treatment resistance><treatment response><treatment responsiveness><tumor><tumor cell metastasis><tumor microenvironment>
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Matthew Borzage

CHILDREN'S HOSPITAL OF LOS ANGELES, LOS ANGELES, CA

Exploratory lead · 18/100
Active award
Career award
$185,212
FY 2025

Project Title

Investigation of Cerebral Hemodynamics and Oxygenation Relationships Under Sedation in Children: ICHOR USC

Grant Number:

5K25HL153954-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/10/2021

End Date:

8/31/2026

Project Abstract

Project Summary The broad objective of this research is to use neuroimaging to understand the hemodynamic responses to anesthesia and sedation. Anesthesia and sedation, commonly used in pediatric patients, cause profound and rapid changes in cerebral blood flow and metabolism. Under normal conditi...

Research Terms

<0-11 years old><1 year of age><1 year old><21+ years old><8 year old><8 years of age><Acquired brain injury><Acute><Address><Adult><Adult Human><Aerobic><Affect><Age><Anesthesia><Anesthesia procedures><Anesthestic Drugs><Anesthetic Agents><Anesthetic Drugs><Anesthetics><Animals><Apoptosis><Apoptosis Pathway><Blood flow><Brain><Brain Hypoxia><Brain Hypoxia-Ischemia><Brain Injuries><Brain Nervous System><Brain Trauma><Brain hemodynamics><Calcium><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Cerebrovascular Circulation><Cerebrum><Characteristics><Chemicals><Child><Child Youth><Childhood><Children (0-21)><Clinical><Cognitive><Cohort Studies><Concurrent Studies><Coupled><Coupling><Critical Care><Dendrites><Diagnosis><Diagnostic><Diprivan><Disease><Disoprofol><Disorder><Drugs><Encephalon><Enrollment><Equipoise><Exhibits><Exposure to><Future><Goals><Hypoxia><Hypoxic><Image><Impairment><Individual Differences><Infant><Injury><Intermediary Metabolism><Investigation><Ion Channel><Ionic Channels><Knowledge><Learning><Link><Liquid substance><MR Imaging><MR Tomography><MRI><MRI Scans><MRIs><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Measurement><Measures><Mediating><Medical><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Membrane Channels><Metabolic><Metabolic Processes><Metabolism><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Neonatal asphyxia-induced brain injury><Neonatal hypoxic brain injury><Nerve Cells><Nerve Unit><Neural Cell><Neural Development><Neurocyte><Neurons><Neurotoxins><Nuclear Magnetic Resonance Imaging><O element><O2 element><Outcome><Oxygen><Oxygen Deficiency><Patients><Pharmaceutical Preparations><Pilot Projects><Programmed Cell Death><Propofol><Provider><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Regulation><Reporting><Research><Research Design><Research Grants><Research Project Grants><Research Projects><Risk><Scanning><Sedation procedure><Study Type><Subcellular Process><Techniques><Testing><Translational Research><Translational Science><Traumatic Brain Injury><Zeugmatography><adulthood><adverse consequence><adverse outcome><age 1 year><age 8 years><aged 1 year><aged one year><ages><axon damage><axon injury><axonal damage><axonal injury><behavior outcome><behavioral outcome><blood flow in brain><brain blood circulation><brain blood dynamics><brain blood flow><brain damage><brain metabolism><brain oxygenation><brain-injured><career><cerebral><cerebral blood flow><cerebral circulation><cerebral hemodynamics><cerebral oxygenation><cerebrocirculation><cerebrovascular blood flow><child patients><clinical practice><cognitive performance><cohort><cytotoxic><design><designing><drug/agent><eight year old><eight years of age><enroll><fluid><hemodynamics><hypoxia/ischemia><hypoxic ischemic encephalopathy><image processing><imaging><improved><injuries><kids><liquid><metabolism measurement><metabolomics><metabonomics><neonatal HIE><neonatal brain hypoxia-ischemia><neonatal hypoxia-ischemia><neonatal hypoxic-ischemic brain damage><neonatal hypoxic-ischemic brain injury><neonatal hypoxic-ischemic encephalopathy><neural><neural imaging><neurite growth><neuro-imaging><neurodevelopment><neuroimaging><neurological imaging><neuron toxicity><neuronal><neuronal toxicity><neurotoxicant><neurotoxicity><one year of age><one year old><pediatric><pediatric patients><pilot study><potential biological marker><potential biomarker><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><preference><prevent><preventing><randomisation><randomization><randomly assigned><response><response to therapy><response to treatment><sedation><sedative><sevoflurane><skills><study design><therapeutic response><therapy response><translation research><translational investigation><traumatic brain damage><treatment response><treatment responsiveness><youngster>
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Ji (Carl) Yang

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 18/100
Active award
Career award
$171,310
FY 2025

Project Title

Understanding Diabetes Heterogeneity via Mining Multimodality Interconnected Data

Grant Number:

5K25DK135913-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2023

End Date:

4/30/2028

Project Abstract

Understanding Diabetes Heterogeneity via Mining Multimodality Interconnected Data Abstract. Diabetes is a prevalent and highly heterogeneous disease that incurs tremendous human, economic, and so- cial costs globally. Prediabetes and early-stage type 2 diabetes often do not have single strong indica...

Research Terms

<Adult-Onset Diabetes Mellitus><Amputation><Behavioral><Biological Markers><Biotech><Biotechnology><Blindness><Cardiac Diseases><Cardiac Disorders><Caring><Characteristics><Chronic Disease><Chronic Illness><Clinical><Clinical Data><Complex><Computer software><Connectionist Models><Data><Data Science><Data Set><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Early Diagnosis><Early Intervention><Economic Burden><Economics><Electronic Health Record><Electronics><Environmental Factor><Environmental Risk Factor><Epidemic><Genomics><Goals><Grain><Graph><Health><Health Care><Health Care Systems><Heart Diseases><Heterogeneity><Human><Individual><Information Networks><Institution><Investigators><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><Life Experience><Machine Learning><Maturity-Onset Diabetes Mellitus><Measures><Methods><Mining><Modality><Modeling><Modern Man><Modernization><Molecular><NIDDK><NIDDM><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nephropathy><Neural Network Models><Neural Network Simulation><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Pathologic><Patients><Pattern><Perceptrons><Phenotype><Population><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Production><Records><Renal Disease><Research><Research Personnel><Researchers><Slow-Onset Diabetes Mellitus><Social Interaction><Software><Source><Stable Diabetes Mellitus><Structure><Survey Instrument><Surveys><Symptoms><System><T2 DM><T2D><T2DM><Training><Translating><Translational Research><Translational Science><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><United States National Institutes of Health><adult onset diabetes><advanced analytics><analytical tool><bio-markers><biologic marker><biomarker><chronic disorder><clinical phenotype><clinical practice><clinically actionable><co-morbid><co-morbidity><cohort><combinatorial><comorbidity><complex data><computer science><computer scientist><cost><cost effective therapy><cost effective treatment><data structure><design><designing><developmental><diabetes><diabetes management><diabetes mellitus management><diabetic><diabetic management><diabetic patient><digital><early detection><economic><effective therapy><effective treatment><electronic><electronic device><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><environmental risk><graph attention network><graph convolutional network><graph neural network><health data><heart disorder><high risk><improved><individual heterogeneity><individual patient><individual variability><individual variation><insight><intervention design><ketosis resistant diabetes><kidney disorder><machine based learning><machine learning based model><machine learning model><maturity onset diabetes><multi-modal data><multi-modal datasets><multi-modality><multimodal data><multimodal datasets><multimodality><multiomics><multiple omics><novel><open source><outcome prediction><panomics><patient response><patient specific response><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><pre-diabetes><pre-diabetic><precision medicine><precision-based medicine><prediabetic><prototype><renal disorder><responsive patient><secondary analysis><sensor><social><social factors><therapy design><time interval><translation research><translational investigation><treatment design><treatment effect><treatment strategy><type 2 DM><type II DM><type two diabetes><vision loss><visual loss>
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Atlas Khan

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Exploratory lead · 18/100
Active award
Career award
$169,246
FY 2025

Project Title

Predictive utility of polygenic risk scores for chronic kidney disease.

Grant Number:

5K25DK128563-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/1/2021

End Date:

3/31/2027

Project Abstract

ABSTRACT In this application for a 5-year K25 Career Development Award, I propose a mentored research and career development plan providing a foundation for a future career as an independent investigator in kidney disease. The goal of this research project is to develop and test polygenic risk score...

Research Terms

<Affect><Age><American><Atrial Fibrillation><Auricular Fibrillation><Award><BMI><BMI percentile><BMI z-score><Berger's Disease><Biomedical Research><Body mass index><Breast Cancer><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Characteristics><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Colon Cancer><Colon Carcinoma><Computerized Medical Record><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Data><Data Set><Development><Development Plans><Development and Research><Dimensions><Disease><Disease Progression><Disorder><ESKD><ESRD><Early Diagnosis><Early treatment><Electronic Health Record><Electronic Medical Record><Electronics><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Enrollment><European><Evolution><Extramembranous Glomerulopathy><FSGS><Familiarity><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foundations><Funding><Future><GWA study><GWAS><Gene variant><Genetic><Genetic predisposing factor><Genetic study><Genomic medicine><Genomics><Genotype><Goals><Health Care Systems><IGA Glomerulonephritis><IGA Nephropathy><Individual><Inflammatory Bowel Diseases><Inflammatory Bowel Disorder><Investigators><K-Awards><K-Series Research Career Programs><Kidney Diseases><Knowledge><Life><Link><Malignant Breast Neoplasm><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Mentors><Methods><Modeling><Morbid Obesity><Nephrology><Nephropathy><Obesity><Outcome><Participant><Pathogenesis><Patients><Phenotype><Population><Prevention><Prospective cohort><Public Health><Quetelet index><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Renal Disease><Renal function><Research><Research Career Program><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Risk><Risk Factors><Risk Marker><SNP array><SNP chip><Sampling><Severe obesity><Testing><Time><Training><United Kingdom><Variant><Variation><adiposity><ages><allelic variant><atherosclerotic coronary disease><biobank><biomed informatics><biomedical informatics><biorepository><cancer in the colon><career><career development><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><chronic disorder><chronic kidney disease><clinical applicability><clinical application><co-morbid><co-morbidity><cohort><comorbidity><coronary arterial disease><corpulence><density><developmental><direct application><disease diagnosis><disease risk><disorder risk><early detection><early therapy><electronic><electronic device><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><ethnic diversity><ethnically diverse><extreme obesity><focal glomerulonephritis><genetic risk factor><genetic variant><genome medicine><genome scale><genome wide association><genome wide association scan><genome wide association study><genome-wide><genomewide><genomewide association scan><genomewide association study><genomic variant><high risk><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><improved><inflammatory disease of the intestine><inflammatory disorder of the intestine><inherited factor><intestinal autoinflammation><kidney disorder><kidney function><life-time risk><lifetime risk><low-frequency mutation><malignant breast tumor><mortality><novel><patient centered><patient oriented><phenome><phenotypic data><polygenetic risk scores><polygenic predictors><polygenic risk score><polygenic scores><rare allele><rare mutation><rare variant><recruit><renal disorder><research and development><risk predictor><risk predictors><segmental glomerulonephritis><single nucleotide polymorphism array><single nucleotide polymorphism chip><whole genome association analysis><whole genome association study>
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Cuihua Wang

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 18/100
Active award
Career award
$152,550
FY 2024

Project Title

Tracking M2-Like Macrophages in Cardiopulmonary Diseases by Magnetic Resonance Imaging

Grant Number:

5K25HL150305-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/15/2019

End Date:

7/31/2026

Project Abstract

Project Summary I am currently an Instructor in the Department of Radiology at Massachusetts General Hospital and Harvard Medical School. My long-term career goal is to become an independent investigator in biomarker imaging development and translation to better understand and diagnose inflammation ...

Research Terms

<(TNF)-α><Advisory Committees><Affinity><After Care><After-Treatment><Aftercare><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Assay><B cell growth factor><B-Cell Differentiation Factor-1><B-Cell Growth Factor-1><B-Cell Growth Factor-I><B-Cell Proliferating Factor><B-Cell Stimulating Factor><B-Cell Stimulating Factor-1><B-Cell Stimulation Factor-1><B-Cell Stimulatory Factor-1><B7-1><BB1><BCDF-1><BCGF><BCGF-1><BCSF 1><BSF-1><BSF1><Bacteria><Binding><Binetrakin><Bioassay><Biodistribution><Biological><Biological Assay><Body Tissues><CD28LG><CD28LG1><CD80><CD80 gene><CSIF><CSIF-10><Cachectin><Cancers><Cardiac infarction><Cardiopulmonary><Cell Body><Cells><Colony-Stimulating Factors><Communities><Cor pulmonale><Cytokine Synthesis Inhibitory Factor><D-Mannose><Data><Deoxygalactose><Detection><Development><Diagnosis><Diagnostic><Disease><Disease Progression><Disorder><Drug Kinetics><Dysfunction><Educational workshop><Equilibrium><Evolution><Fibrosis><Fucose><Functional disorder><Future><General Hospitals><General Radiology><Glial Cell Tumors><Glial Neoplasm><Glial Tumor><Glioma><Goals><Grant><Hepatic Proliferation Inhibitor><Heterogeneity><Human><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><IL-10><IL-4><IL10><IL10A><IL4 Protein><Image><Immune Interferon><Immunology><In Vitro><Inflammation><Inflammatory><Innate Immunity><Interferon Gamma><Interferon Type II><Interleukin 10 Precursor><Interleukin-10><Interleukin-4><Interleukin-4 Precursor><Investigators><Knowledge><L arginine amidinohydrolase><LAB7><Ligands><Liver Immunoregulatory Protein><Liver-Derived Inhibitory Protein><Lung Carcinoma><Lymphocyte Stimulatory Factor 1><Lytotoxicity><MCGF-2><MGI-1 Protein><MR Imaging><MR Tomography><MRI><MRIs><Macrophage><Macrophage-Derived TNF><Magnetic Resonance Imaging><Malignant Neoplasms><Malignant Tumor><Mannopyranose><Mannopyranoside><Mannose><Maps><Massachusetts><Mast Cell Growth Factor-2><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Mentorship><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Modern Man><Molecular Interaction><Monitor><Monocyte-Derived TNF><Myeloid Cell-Growth Inducer><Myocardial Infarct><Myocardial Infarction><Mφ><NMR Imaging><NMR Tomography><Native Immunity><Natural Immunity><Neoplasm Metastasis><Neuroglial Neoplasm><Neuroglial Tumor><Non-Specific Immunity><Nonspecific Immunity><Nuclear Magnetic Resonance Imaging><Pathologic><Pathologic Processes><Pathological Processes><Pharmacokinetics><Phenotype><Physiopathology><Play><Production><Pulmonary Heart Disease><Pulmonary Heart Disorder><Radiology><Radiology Specialty><Reporting><Research><Research Personnel><Researchers><Role><Secondary Neoplasm><Secondary Tumor><Sensitivity and Specificity><Skin wound healing><Structure-Activity Relationship><Surface><Systems Biology><T-Cell Growth Factor 2><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Task Forces><Technology><Tissues><Training><Translating><Translations><Treatment Efficacy><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Tumor Promotion><Tumor-associated macrophages><Workshop><Wound Repair><Wound models><Writing><Zeugmatography><advisory team><alpha-Fucose><analog><arginase><arginine amidinase><bactericidal><bactericide><balance><balance function><biologic><biomedical imaging><canavanase><cancer metastasis><cardiac infarct><cardiopulmonary disease><cardiopulmonary disorder><cardiovascular imaging><career><chemical structure function><conference><convention><coronary attack><coronary infarct><coronary infarction><cutaneous wound healing><cytotoxicity><dermal wound healing><design><designing><developmental><experience><experiment><experimental research><experimental study><experiments><fungus><glial-derived tumor><healing><heart attack><heart infarct><heart infarction><image-based method><imaging><imaging agent><imaging biomarker><imaging in vivo><imaging marker><imaging method><imaging modality><imaging probe><imaging-based biological marker><imaging-based biomarker><imaging-based marker><in vitro Assay><in vivo><in vivo imaging><inhibitor><instructor><intervention efficacy><lFN-Gamma><malignancy><mannose receptor><medical college><medical schools><meeting><meetings><mouse model><murine model><neoplasm/cancer><neuroglia neoplasm><neuroglia tumor><non-invasive imaging><noninvasive imaging><pathogenic virus><pathophysiology><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><post treatment><pre-clinical study><preclinical study><prototype><repair><repaired><response><response to therapy><response to treatment><school of medicine><screening><screenings><social role><spatiotemporal><structure function relationship><summit><symposia><symposium><targeted agent><therapeutic efficacy><therapeutic response><therapeutic target><therapy efficacy><therapy response><tissue repair><tool><translation><treatment response><treatment responsiveness><tumor><tumor cell metastasis><tumor growth><viral pathogen><virus pathogen><wound healing><wound healing models><wound recovery><wound resolution>
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Mandana Rezaeiahari

UNIV OF ARKANSAS FOR MED SCIS, LITTLE ROCK, AR

Exploratory lead · 18/100
Active award
Career award
$149,502
FY 2025

Project Title

Understanding Utilization of Diabetes Self-Management Education and Support Using Social Network Analysis

Grant Number:

5K25DK136966-02

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2024

End Date:

4/30/2028

Project Abstract

PROJECT SUMMARY Diabetes Self-Management Education and Support (DSMES) addresses the clinical, psychological, and behavioral aspects of care needed to successfully self-manage diabetes. Despite the proven value of the DSMES on patient outcomes, it remains underutilized. Only a small fraction of pati...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Address><Adopted><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aged 65 and Over><Apoplexy><Arkansas><Awareness><Behavior><Behavioral><Blindness><Brain Vascular Accident><Cardiovascular Diseases><Caring><Cause of Death><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Clinical><Collaborations><Communication><Complex><Data><Data Analytics><Data Bases><Databases><Diabetes Mellitus><Diagnosis><Diffusion><Diffusion of Innovation><Drugs><Education><Educational aspects><Eligibility><Eligibility Determination><Enrollment><Exercise><Foundations><Funding><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care Professional><Health Insurance><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Health Professional><Health Status><Hemoglobin A(1)><Individual><Influentials><Insurance><Intervention><Intervention Strategies><Investigators><Ketosis-Resistant Diabetes Mellitus><Kidney Failure><Kidney Insufficiency><Knowledge><Lead><Leadership><Level of Health><Logistic Regressions><Logistics><Lower Extremity><Lower Limb><Maturity-Onset Diabetes Mellitus><Measures><Medicare><Medicare claim><Medication><Membrum inferius><Mentors><Methodology><Methods><Modeling><NIDDM><Network Analysis><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition><Pathway Analysis><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pb element><Pharmaceutical Preparations><Physicians><Population><Position><Positioning Attribute><Prevalence><Privatization><Productivity><Protocol Screening><Provider><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Regression Analyses><Regression Analysis><Regression Diagnostics><Renal Failure><Renal Insufficiency><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Role><Rural><Science><Services><Slow-Onset Diabetes Mellitus><Social Network><Stable Diabetes Mellitus><Statistical Methods><Statistical Regression><Stroke><Structure><Survey Instrument><Surveys><System><T2 DM><T2D><T2DM><Testing><Title 18><Training><Translational Research><Translational Science><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><above age 65><adult onset diabetes><adulthood><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged><aged 65 and greater><aged 65+><aged ≥65><amputated limb><brain attack><burden of disease><burden of illness><cardiovascular disorder><care for patients><care of patients><care providers><career><caring for patients><cerebral vascular accident><cerebrovascular accident><cost effectiveness><data base><density><design><designing><diabetes><diabetes education><diabetes management><diabetes mellitus management><diabetes self-care><diabetes self-management><diabetic management><diffused><diffuses><diffusing><diffusions><disease burden><drug/agent><effective intervention><enroll><health insurance for disabled><health insurance plan><health level><heavy metal Pb><heavy metal lead><hemoglobin A1c><human old age (65+)><improved><innovate><innovation><innovative><insurance claims><ketosis resistant diabetes><limb amputation><maturity onset diabetes><medical claims><member><multidisciplinary><network models><over 65 years><patient barriers><patient oriented outcomes><patient-level barriers><population health><programs><provider barriers><provider networks><provider-level barriers><psychologic><psychological><rural dwelling><rural households><rural residence><social><social role><statistic methods><statistics><stress buffering><stress management><stroked><strokes><systematic review><theories><tool><translation research><translational investigation><type 2 DM><type II DM><type two diabetes><uptake><urban residence><vision loss><visual loss><≥65 years>
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Roy Adams

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 18/100
Active award
Career award
$146,070
FY 2025

Project Title

Machine learning-based methods for phenotyping dementia patients from electronic health record data

Grant Number:

5K25AG083064-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/15/2023

End Date:

7/31/2027

Project Abstract

PROJECT SUMMARY/ABSTRACT Candidate: Dr. Roy Adams applies for this K25 Mentored Quantitative Research Career Development Award with the goal of building a productive independent research career as a methodologist focused on developing electronic health record (EHR)-based models and tools to improve ...

Research Terms

<AD dementia><AD detection><AD related dementia><ADRD><Address><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease detection><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's care><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's detection><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease care><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimers Dementia><Amentia><Area><Big Data><BigData><Biological><Biology><Calibration><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Clinical><Code><Coding System><Complex><Computer software><Computing Methodologies><Data><Data Bases><Databases><Dementia><Development><Diagnosis><Disease><Disorder><Drugs><Electronic Health Record><Environment><Equity><Error Sources><Exposure to><Family><Foundations><Funding><Future><Goals><Heterogeneity><Investigators><Journals><K-Awards><K-Series Research Career Programs><Lead><Learning><Longitudinal Studies><Machine Learning><Magazine><Measurement><Measures><Medication><Memory><Mentors><Methodology><Methods><Modeling><NIH><National Institutes of Health><Outcome><Pathology><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pb element><Persons><Pharmaceutical Preparations><Phenotype><Precision Medicine Initiative><Primary Senile Degenerative Dementia><Productivity><Proxy><Psychiatric epidemiology><Public Health><Research><Research Career Program><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Factors><Sample Size><Selection Bias><Severities><Software><Source><Time><Training><United States National Institutes of Health><Validity and Reliability><Work><access to health care><accessibility of health care><accessibility to health care><alzheimer risk><barrier to care><barrier to health care><barrier to treatment><biologic><care for patients><care fragmentation><care of patients><career><caring for patients><clinical development><cohort><computational methodology><computational methods><computational resources><computer based method><computer methods><computing method><computing resources><cost><data base><data to train><dataset to train><dementia care><depository><detection method><detection procedure><detection technique><developmental><diagnosis standard><disease heterogeneity><drug/agent><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><experience><geriatric neuropsychiatry><health care access><health care availability><health care service access><health care service availability><health data><heavy metal Pb><heavy metal lead><high dimensionality><high risk><improved><interest><large scale data><large scale data sets><large scale datasets><long-term study><longitudinal outcome studies><machine based learning><machine learning based method><machine learning method><machine learning methodologies><model building><obstacle to care><obstacle to health care><open source><patient oriented outcomes><patient population><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><precision medicine><precision-based medicine><primary degenerative dementia><repository><senile dementia of the Alzheimer type><skills><supervised learning><supervised machine learning><tool><training data><treatment center>
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Wensi Wu

CHILDREN'S HOSP OF PHILADELPHIA, PHILADELPHIA, PA

Exploratory lead · 18/100
Active award
Career award
$144,141
FY 2025

Project Title

Toward Patient-Specific Computational Modeling of Tricuspid Valve Repair in Hypoplastic Left Heart Syndrome

Grant Number:

5K25HL168235-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2023

End Date:

8/31/2027

Project Abstract

PROJECT SUMMARY/ABSTRACT Hypoplastic left heart syndrome (HLHS) is characterized by maldevelopment of the left heart and affects over 1000 live-born infants annually in the U.S. Neonates with HLHS undergo three staged open-chest reconstruction surgeries to create normal blood flood through the heart...

Research Terms

<0-11 years old><3-D Echocardiography><3D Echocardiography><Address><Affect><Age><Anatomic Sites><Anatomic structures><Anatomy><Animal Model><Animal Models and Related Studies><Area><Award><Biomechanics><Biomedical Research><Blood><Blood Reticuloendothelial System><Body Tissues><Cardiac><Cardiac Valves><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Causality><Chest><Child><Child Youth><Childhood><Children (0-21)><Children's Hospital><Circulation><Clinical><Communities><Computational Science><Computer Analysis><Computer Models><Computerized Models><Data><Development><Doctor of Philosophy><Drug or chemical Tissue Distribution><Dysfunction><Elements><Engineering><Environment><Etiology><Exposure to><Extravasation><Failure><Finite Element Analyses><Finite Element Analysis><Flooding><Floods><Functional disorder><Future><Geometry><Goals><Heart><Heart Valve Diseases><Heart Valves><Heart Vascular><Heart failure><Height><Heterogeneity><Hypoplastic Left Heart Syndrome><Hypoplastic Left Ventricle><Image><Individual><Infant><Interrupted Aortic Arch><Intervention><Investigation><Investigators><Leakage><Learning><Left><Machine Learning><Mentors><Methods><Modeling><Morbidity><Morbidity - disease rate><Morphology><Operative Procedures><Operative Surgical Procedures><Pathology><Patients><Pediatric Hospitals><Pennsylvania><Ph.D.><PhD><Phase><Philadelphia><Physics><Physiopathology><Population><Population Heterogeneity><Position><Positioning Attribute><Procedures><Property><Reconstructive Surgical Procedures><Research><Research Personnel><Researchers><Risk><Science><Scientist><Series><Severities><Single ventricle congenital heart disease><Spillage><Stress><Structure><Surgical><Surgical Interventions><Surgical Procedure><Surgical Simulation><Survivors><Techniques><Technology><Thorace><Thoracic><Thorax><Three-Dimensional Echocardiography><Tissue Distribution><Tissues><Training><Translating><Tricuspid Incompetence><Tricuspid Regurgitation><Tricuspid Valve><Tricuspid Valve Incompetence><Tricuspid Valve Insufficiency><Tricuspid Valve Regurgitation><Tricuspid valve structure><Universities><Valvular Heart Diseases><Valvular Heart Disorder><Work><ages><biomechanical><cardiac failure><cardiac valve disease><cardiac valve disorder><cardiac valvular disease><cardiovascular disorder><career><causation><circulatory system><clinical translation><clinically translatable><cohort><computational analyses><computational analysis><computational framework><computational modeling><computational models><computational studies><computer analyses><computer based models><computer framework><computer studies><computerized modeling><data to train><dataset to train><death risk><degenerative valvular heart disease><design><designing><developmental><disease causation><diverse populations><heart valve disorder><heterogeneous population><hypoplastic left heart><hypoplastic left syndrome><image registration><imaging><improved><indexing><individual patient><insight><kids><knowledge base><machine based learning><model of animal><mortality><mortality risk><multidisciplinary><neonate><novel><pathophysiology><pediatric><population diversity><prevent><preventing><reconstruction surgery><reconstructive surgery><repair><repaired><response><scientific computing><shape analysis><shape description><single ventricle congenital heart defect><single ventricle defect><single ventricle disease><single ventricle heart defect><single ventricle heart disease><skills><sound><success><surgery><surgery outcome><surgical outcome><tissue stress><training data><virtual><virtual reality surgery><virtual surgery><youngster>
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fei jiang

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 18/100
Active award
Career award
$132,696
FY 2025

Project Title

Development of Dynamic Resting State Functional Connectivity Machine Learning Framework for Dementia

Grant Number:

5K25AG071840-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/15/2022

End Date:

5/31/2027

Project Abstract

Project Summary/Abstract The objective of this proposal is to provide a robust course of training for Fei Jiang, Ph.D., a candidate with an excellent foundation in statistical and machine learning research, to enable her to become an independent investigator in the field of quantitative data analysis...

Research Terms

<AD dementia><Address><Affect><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Amentia><Area><Award><Benchmarking><Best Practice Analysis><Biological Markers><Biometrics><Biometry><Biostatistics><Brain><Brain Nervous System><Characteristics><Clinical><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Data><Data Analyses><Data Analysis><Degenerative Neurologic Disorders><Dementia><Development><Disturbance in cognition><Doctor of Medicine><Doctor of Philosophy><EEG><Electroencephalogram><Electroencephalography><Encephalon><Epidemiology><Foundations><Functional Imaging><Functional MRI><Functional Magnetic Resonance Imaging><Goals><Image><Imaging Procedures><Imaging Technics><Imaging Techniques><Impaired cognition><Individual><Intervention><Investigators><Knowledge><Learning><M.D.><Mentors><Methodology><Methods><Monitor><Multimodal Imaging><Nature><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurologic Dysfunctions><Neurology><Neurosciences><Pattern><Persons><Ph.D.><PhD><Physiologic Imaging><Primary Senile Degenerative Dementia><Procedures><Radiography><Research><Research Personnel><Researchers><Rest><Risk Reduction><Roentgenography><Sampling><Symptoms><Technical Expertise><Testing><Time><Training><Treatment Efficacy><United States><Validation><Work><benchmark><bio-markers><biologic marker><biomarker><biomedical imaging><career><cognitive assessment><cognitive change><cognitive dysfunction><cognitive loss><cognitive performance><cognitive testing><computer based prediction><data interpretation><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><developmental><early screening><efficacious therapy><efficacious treatment><epidemiologic><epidemiological><fMRI><feature extraction><feature selection><high dimensionality><image-based method><imaging><imaging biomarker><imaging marker><imaging method><imaging modality><imaging-based biological marker><imaging-based biomarker><imaging-based marker><intervention design><intervention efficacy><machine learning based framework><machine learning based method><machine learning based model><machine learning framework><machine learning method><machine learning methodologies><machine learning model><machine statistical learning><method development><multi-modal imaging><multi-modal neuro-imaging><multi-modality imaging><multidisciplinary><multimodal neuroimaging><multimodality imaging><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological dysfunction><neurological imaging><next generation><physiological imaging><predictive modeling><prevent><preventing><primary degenerative dementia><radiological imaging><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><senile dementia of the Alzheimer type><spatial and temporal><spatial temporal><spatiotemporal><statistical and machine learning><success><technical skills><therapeutic efficacy><therapy design><therapy efficacy><treatment design><treatment effect><validations>
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Shelley Han Liu

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

Exploratory lead · 18/100
Active award
Career award
$129,882
FY 2025

Project Title

Improving precision in modeling childhood executive function trajectories using psychometrics

Grant Number:

5K25HD104918-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/1/2021

End Date:

6/30/2026

Project Abstract

Project Summary: Executive functions are high-level supervisory cognitive skills vital for a child’s social and academic success. Their core components include working memory, inhibitory control and cognitive flexibility. The development of executive functions in children can be adversely affected b...

Research Terms

<0-11 years old><AC Globulin><Address><Advisory Committees><Affect><Age><Biological><Biometrics><Biometry><Biostatistics><Birth><Blood Coagulation Factor V><Boston><Child><Child Youth><Childhood><Children (0-21)><Cities><Clinical><Coagulation Factor V><Cognitive><Committee Members><Communities><Complement><Complement Proteins><Complex><Computer software><Data><Development><Dimensions><Dose><Ensure><Environment><Equation><Exposure to Pb2+><Factor Analyses><Factor Analysis><Factor Pi><Factor V><Fetal Pb-exposure><Funding><Generalized Growth><Genetic><Goals><Growth><Health Policy><Health Sciences><Immediate Memory><Individual><International><Intervention><Intervention Strategies><Investigators><Joints><Knowledge><Lead><Letters><Life><Life course epidemiology><Lifecourse epidemiology><Link><Literature><Machine Learning><Measurement><Measures><Mentors><Methods><Mexico><Modeling><NIH><National Institutes of Health><Neural Development><Neuropsychologies><Neuropsychology><New York City><Nutrition><Output><Parturition><Pb element><Pb exposed><Pb exposure><Pb2+ Exposure><Pb2+ exposed><Predictive Factor><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Proaccelerin><Process><Psychometrics><Research><Research Personnel><Researchers><Risk Factors><Role><Rotation><Short-Term Memory><Socio-economic status><Socioeconomic Status><Software><Structure><Task Forces><Task Performances><Testing><Time><Tissue Growth><Training><United States National Institutes of Health><Variant><Variation><advisory team><ages><biologic><career><cognitive skill><cohort><complementation><develop software><developing computer software><developmental><environmental stresses><environmental stressor><executive control><executive function><exposed to lead><exposure to Pb><exposure to lead><fetal exposure to lead><fetal lead exposure><flexibility><flexible><health care policy><heavy metal Pb><heavy metal lead><improved><interest><kids><labile component><labile factor><lead exposed><lead exposure><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><machine based learning><machine learning based model><machine learning model><maternal stress><medical college><medical schools><meeting><meetings><multi-modality><multimodality><neurobehavior><neurobehavioral><neurodevelopment><neuropsychologic><online app><ontogeny><open source><pediatric><population health><postnatal><prenatal><prenatal exposure to lead><prenatal lead exposure><prenatally exposed to lead><prenatally lead exposed><prevent><preventing><professor><programs><prospective><response><school of medicine><skills><social><social role><social stresses><social stressor><socio-economic position><socioeconomic position><software development><statistics><stressed mothers><success><theories><tool><unborn><user friendly computer software><user friendly software><web app><web application><web based app><web based application><working memory><youngster>
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Matthew Frederick Campbell

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 18/100
Active award
Career award
$114,345
FY 2025

Project Title

Rapidly Adaptable and Mass-Producible Microscopic Chiplets for Minimally-Instrumented Respiratory Viral Screening

Grant Number:

5K25AI166040-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/10/2022

End Date:

7/31/2027

Project Abstract

Project Summary Objective: Respiratory viral infections affect millions of individuals each year. Conducting frequent widespread viral screening tests can curb outbreaks by quickly identifying infectious persons. Unfortunately, no screening diagnostic platform exists with the capacity to test hundre...

Research Terms

<2-dimensional><2019 novel corona virus><2019 novel coronavirus><2019-nCoV><Acceleration><Affect><Airway infections><Algorithms><Antibodies><Antigens><Applied Research><Applied Science><Area><Assay><Award><Bioassay><Biological><Biological Assay><Biology><Biomedical Engineering><Biomedical Research><Biosensor><COVID crisis><COVID detection><COVID epidemic><COVID pandemic><COVID-19><COVID-19 crisis><COVID-19 detection><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 virus><COVID-19 years><COVID19 detection><COVID19 virus><CV-19><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cations><Cell Phone><Cellular Phone><Cellular Telephone><Chemicals><Clinical><CoV emergence><CoV-2><CoV2><Containment><Coronavirus Infectious Disease 2019><Data Bases><Databases><Development><Development Plans><Diagnostic><Disease><Disease Outbreaks><Disorder><Doctor of Medicine><Economic Burden><Electric Conductivity><Electrical Conductivity><Engineering><Environment><Epidemic><Eye><Eyeball><Funding><Future><Goals><Grippe><Gross Domestic Product><Gross National Income><Gross National Product><Human><Immobilization><Immunoassay><Individual><Influenza><Investigation><Investigators><K-Awards><K-Series Research Career Programs><Label><Leanness><Light><M.D.><MERS corona virus><MERS coronavirus><MERS virus><MERS-CoV><Measurement><Medical><Mentors><Mentorship><Methods><Microscopic><Middle East Respiratory Syndrome Corona Virus><Middle East Respiratory Syndrome Coronavirus><Middle East Respiratory Syndrome Virus><Middle East Respiratory Syndrome-CoV><Middle East Respiratory Virus><Middle East Respiratory coronavirus><Middle Eastern Respiratory Syndrome Corona virus><Middle Eastern Respiratory Syndrome Coronavirus><Middle Eastern Respiratory Syndrome Virus><Middle Eastern Respiratory Syndrome-CoV><Mobile Phones><Modern Man><Mucous body substance><Mucus><NIH><National Institutes of Health><Nucleic Acids><Optics><Outbreaks><Patients><Pennsylvania><Persons><Photoradiation><Plants><Play><Population><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Procedures><Production><Property><Reader><Receptor Protein><Research><Research Associate><Research Career Program><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Respiratory Infections><Respiratory Tract Infections><SARS Virus><SARS corona virus><SARS corona virus 2><SARS coronavirus><SARS-Associated Coronavirus><SARS-CO-V2><SARS-COVID-2><SARS-CoV><SARS-CoV-1><SARS-CoV-2><SARS-CoV-2 detection><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-CoV2><SARS-Related Coronavirus><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Sampling><Scheme><Schools><Secure><Semiconductors><Severe Acute Respiratory Coronavirus><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe Acute Respiratory Syndrome Virus><Severe Acute Respiratory Syndrome corona virus><Severe Acute Respiratory Syndrome coronavirus><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severe acute respiratory syndrome related corona virus 2><Si element><Silicon><Solvents><Source><Specificity><Specimen><Surface><Swab><System><Test Result><Testing><Thinness><Training><Transistors><United States><United States National Institutes of Health><Universities><Viral><Viral Respiratory Tract Infection><Virus><Work><Wuhan coronavirus><antigen binding><antigen bound><aptamer><bio-engineered><bio-engineers><bioengineering><biologic><biological engineering><biological sensor><career><career development><clinical relevance><clinically relevant><combat><contagion><corona virus emergence><coronavirus detection><coronavirus disease 2019><coronavirus disease 2019 crisis><coronavirus disease 2019 detection><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease 2019 virus><coronavirus disease crisis><coronavirus disease detection><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><coronavirus disease-19 virus><coronavirus emergence><coronavirus infectious disease-19><data base><data exchange><data transfer><data transmission><design><designing><detect COVID><detect COVID-19><detect COVID19><detect SARS-CoV-2><detect coronavirus><detect coronavirus disease><detect severe acute respiratory syndrome coronavirus 2><detector><developmental><diagnostic platform><diagnostic screening><diagnostic system><electrical conductance><emergent CoV><emergent corona virus><emergent coronavirus><emergent virus><emerging CoV><emerging corona virus><emerging coronavirus><emerging virus><experience><fabrication><feasibility testing><flexibility><flexible><future pandemic><hCoV19><handheld device><handheld equipment><human disease><iPhone><immunogen><instrument><integrated circuit><integrated circuits><light emission><manufacture><mucous><multiplex detection><nCoV><nCoV2><nanofabricate><nanofabrication><nanowire><new CoV><new corona virus><new coronavirus><next pandemic><novel><novel CoV><novel corona virus><novel coronavirus><optical><orthopedic freezing><pandemic><pandemic disease><point of care><portability><post-doc><post-doctoral><post-doctoral trainee><professor><receptor><research associates><respiratory><response><saliva sample><salivary sample><screening><screenings><seasonal flu><seasonal influenza><sensor><severe acute respiratory syndrome coronavirus 2 detection><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><severe acute respiratory syndrome-CoV><signal processing><skills><smart phone><smartphone><tenure process><tenure track><tool><two-dimensional><viral detection><viral emergence><viral respiratory infection><virus detection><wireless>
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Jaime Lynn Speiser

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Exploratory lead · 18/100
Active award
Career award
$111,087
FY 2025

Project Title

Development and Validation of a Prediction Model for Longitudinal Fall Risk in Older Adults

Grant Number:

5K25AG068253-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/15/2021

End Date:

3/31/2027

Project Abstract

ABSTRACT My goal is to establish myself as an independent biostatistical researcher who develops and validates prediction models that are critical to identifying older adults at high risk of adverse health outcomes using novel machine learning methodology. My passion for developing prediction models...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Active Follow-up><Address><Aged 65 and Over><Aging><Award><Big Data><BigData><Biometrics><Biometry><Biostatistics><Body Composition><Care Givers><Caregivers><Caring><Clinical><Communication><Dangerousness><Data><Data Analyses><Data Analysis><Data Set><Dedications><Dependence><Development><Development and Research><Early identification><Educational workshop><Elderly><Electronic Health Record><Environment><Future><Geriatrics><Gerontology><Goals><Grant><Health><Health Care><Health Care Systems><Individual><Informatics><Investigators><Journals><Knowledge><Knowledge acquisition><Leadership><Learning><Long-term cohort study><Longitudinal cohort study><Machine Learning><Magazine><Measurement><Measures><Medicine><Mentors><Methodology><Methods><Modeling><Morbidity><Morbidity - disease rate><Outcome><Outcome Measure><Participant><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Performance><Persons><Predictive Value><Preventative care><Preventative intervention><Preventive care><Provider><R & D><R&D><Research><Research Personnel><Research Proposals><Researchers><Risk><Risk Factors><Sampling><Statistical Methods><Techniques><Testing><Time><Training><Trees><Validation><Visit><Work><Workshop><Writing><above age 65><active followup><advanced age><adverse consequence><adverse outcome><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><aging process><career><career development><computer based prediction><conference><convention><critical injury><data imputation><data interpretation><decline in function><decline in functional status><devastating injury><developmental><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><experience><fall risk><falls><follow up><follow-up><followed up><followup><forest><functional decline><functional status><functional status decline><geriatric><geriatric medicine><gerontologic><health data><high risk><human old age (65+)><improved><imputation method><innovate><innovation><innovative><intervention for prevention><machine based learning><machine learning based method><machine learning based model><machine learning method><machine learning methodologies><machine learning model><measurable outcome><medical college><medical schools><mortality><novel><older adult><older adulthood><outcome measurement><over 65 years><patient oriented outcomes><predictive modeling><prevention intervention><preventional intervention strategy><preventive intervention><research and development><research study><school of medicine><senior citizen><severe injury><skills><statistic methods><stem><summit><symposia><symposium><validations><≥65 years>
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Ran An

UNIVERSITY OF HOUSTON, HOUSTON, TX

Exploratory lead · 18/100
Active award
Career award
$106,486
FY 2025

Project Title

Roles of Red Blood Cell Derived Extracellular Vesicles in Complement Activation and Thromboinflammation in sickle cell disease

Grant Number:

5K25HL159358-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/19/2023

End Date:

7/31/2027

Project Abstract

PROJECT SUMMARY Sickle cell disease (SCD) is caused by abnormal polymerization of deoxygenated sickle hemoglobin, which damages red blood cells (RBCs), resulting in hemolysis and thromboinflammation. Sickled-RBCs lead to heterogeneous clinical complications in SCD and induce challenges in determinin...

Research Terms

<Abnormal Erythrocytes><Abnormal Red Blood Cell><Acetylcysteine><Acetylin><Adhesions><Airbron><Animal Model><Animal Models and Related Studies><Assay><Autologous><Award><Bioassay><Biological Assay><Biological Markers><Biomedical Research><Blood Plasma><Blood Sample><Blood Vessels><Blood erythrocyte><Blood specimen><Broncholysin><Brunac><Caring><Cell Adhesion><Cell Body><Cell surface><Cells><Cellular Adhesion><Characteristics><Chemical Engineering><Clinical><Clinical Evaluation><Clinical Testing><Clotting><Coagulation><Coagulation Process><Complement><Complement Activation><Complement Proteins><Cyclicity><Cytolysis><DNA mutation><Data><Data Bases><Databases><Deep Vein Thrombosis><Deep-Venous Thrombosis><Deoxygenated Sickle Hemoglobin><Deoxyhemoglobin S><Deposit><Deposition><Diagnosis><Disease><Disease Outcome><Disorder><Drug Metabolic Detoxication><Drug Metabolic Detoxification><ELISA><EZF protein><Endothelial Cells><Endothelium><Enzyme-Linked Immunosorbent Assay><Erythrocytes><Erythrocytic><Evaluation><Exhibits><Exposure to><Fabrol><Ferroprotoporphyrin><Fluatox><Fluimucetin><Fluimucil><Fluprowit><GKLF protein><Gasser's Syndrome><Generations><Genetic Change><Genetic defect><Genetic mutation><Hb SS disease><HbSS disease><Heme><Hemoglobin S><Hemoglobin S Disease><Hemoglobin sickle cell disease><Hemoglobin sickle cell disorder><Hemolysis><Hemolytic-Uremic Syndrome><Hemopexin><History><Hydroxycarbamid><Hydroxycarbamide><Hypoxemia><Hypoxia><Hypoxic><Immunoblotting><In Vitro><Individual><Inflammation><Inflammatory><Inpatients><Klf4 protein><Knowledge><Kruppel-like factor 4><Laboratories><Lead><Leukocyte Count><Leukocyte Number><Lysis><Malaria><Marrow erythrocyte><Mediating><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Mercapturic Acid><Metabolic Drug Detoxications><Metabolism of Toxic Agents><Mice><Mice Mammals><Microfluidics><Morbidity><Morbidity - disease rate><Muco Sanigen><Mucocedyl><Mucolator><Mucolyticum><Mucomyst><Mucosolvin><Mucret><Murine><Mus><Mutation><N-Acetylcysteine><NAC Zambon><Neo-Fluimucil><Out-patients><Outcome><Outpatients><Oxidative Stress><Oxygen Deficiency><Pain><Painful><Paludism><Parents><Parvolex><Pathologic><Pathway interactions><Patients><Pb element><Periodicity><Persons><Phenotype><Phosphatidylserines><Physiologic><Physiological><Plasma><Plasma Serum><Plasmodium Infections><Play><Polymers><Population Heterogeneity><Predisposition><Process><Prognosis><Property><Proteomics><Protoheme><RT-PCR><Recording of previous events><Red Blood Cells><Red Cell><Regulation><Respaire><Reticuloendothelial System, Serum, Plasma><Reverse Transcriptase Polymerase Chain Reaction><Rhythmicity><Risk><Role><Sampling><Scientist><Serine Phosphoglycerides><Sickle Cell><Sickle Cell Anemia><Sickle Hemoglobin><Stress><Surface><Surface Proteins><Susceptibility><Suspension substance><Suspensions><System><Testing><Therapeutic Intervention><Thrombase><Thrombin><Thrombosis><Thrombus><Tixair><Transcriptional Control><Transcriptional Regulation><Transfusion><Treatment Efficacy><Western Blotting><Western Immunoblotting><White Blood Cell Count><White Blood Cell Count procedure><bio-markers><biologic marker><biomarker><blood corpuscles><candidate selection><clinical test><co-morbid><co-morbidity><comorbidity><complement pathway regulation><complement system><complementation><data base><deoxy-HbS><detoxification><diverse populations><emergency settings><enzyme linked immunoassay><epithelial zinc finger protein><erythrolysis><experience><extracellular vesicles><ferroheme><fibrinogenase><genome mutation><gut-enriched Kruppel-like factor><heavy metal Pb><heavy metal lead><heterogeneous population><histories><hydroxy-urea><hydroxyurea><hypoxemic><improved><individual patient><intervention efficacy><intervention therapy><model of animal><mortality><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><parent><pathway><patient population><patient response><patient specific response><polymer><polymeric><polymerization><population diversity><pre-clinical assessment><preclinical assessment><predict clinical outcome><protein blotting><protein expression><research clinical testing><response><response to therapy><response to treatment><responsive patient><reverse transcriptase PCR><screening><screenings><shear stress><sickle RBC><sickle cell disease><sickle cell disorder><sickle deoxyhemoglobin><sickle disease><sickle erythrocyte><sickle red blood cell><sicklemia><social role><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic efficacy><therapeutic response><therapy efficacy><therapy response><thromboinflammation><thromboinflammatory><thrombotic disease><thrombotic disorder><treatment response><treatment responsiveness><vascular><vascular inflammation><vesicle release><vesicular release><µfluidic>
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Michael William Hast

UNIVERSITY OF DELAWARE, Newark, DE

Exploratory lead · 16/100
Active award
$92,080
FY 2023

Project Title

Localized small molecule delivery to improve tendon-to-bone integration following anterior cruciate ligament reconstruction

Grant Number:

7R03AR082449-02

Activity Code:

R03

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/18/2023

End Date:

8/31/2026

Project Abstract

Bone fractures are common injuries that impact millions of people each year, and poorly healed fractures cause impaired mobility, long-term nursing care, or even premature death. It is known that controlled mechanical loading can improve the quality and speed of fracture repair, but our understandin...

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Yue Xuan

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 8/100
Career award
$176,040
FY 2022

Project Title

Hemodynamics of thrombosis after transcatheter aortic valve-in-valve implantation

Grant Number:

5K25HL150408-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/15/2020

End Date:

1/31/2025

Project Abstract

ABSTRACT I This is an application for a Mentored Quantitative Research Development Award for Dr. Yue Xuan, a biomedical research scientist at the University of California, San Francisco. Dr. Xuan is establishing herself as a young investigator in patient-oriented research of aortic valve replacemen...

Research Terms

<Active Follow-up><Address><Affect><Angiogram><Angiography><Anticoagulation><Aortic Aneurysm><Aortic Stenosis><Aortic Valve Stenosis><Aortic valvular disorders><Applications Grants><Area><Attenuated><Award><Biomechanics><Biomedical Research><Bioprosthesis><Bioprosthesis device><Bioprosthetic><Bleeding><Body Tissues><Bovine Species><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Calcified><California><Cardiac Output><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cattle><Clinical><Clinical Data><Clinical Management><Clinical Research><Clinical Study><Clinical Treatment><Computed Tomography><Computer Models><Computer Simulation><Computer based Simulation><Computerized Models><Data><Development and Research><Discipline><Disease><Disorder><Echocardiogram><Echocardiography><Enrollment><Failure><Family suidae><Future><General Radiology><Goals><Grant Proposals><Guidelines><Heart Vascular><Hemorrhage><Hemostatic Agents><Hemostatics><Hypercoagulability><Impairment><Implant><In Vitro><International><Intervention><Intervention Strategies><Investigation><Investigators><Knowledge><Laboratories><Lead><Liquid substance><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Mechanics><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical center><Mentors><Mentorship><Methods><Modeling><Morbidity><Morbidity - disease rate><Motion><NMR Imaging><NMR Tomography><Names><Nature><Nuclear Magnetic Resonance Imaging><Operative Procedures><Operative Surgical Procedures><Outcome><Outcome Study><Patients><Pattern><Pb element><Persons><Physicians><Pigs><Predictive Factor><Procedures><Publishing><R & D><R&D><Radiology><Radiology Specialty><Registries><Reporting><Research><Research Personnel><Researchers><Risk><Risk Factors><San Francisco><Scientist><Solid><Stress><Structure><Suidae><Supervision><Surface><Surgical><Surgical Interventions><Surgical Procedure><Swine><Symptoms><Thromboembolism><Thrombophilia><Thrombosis><Thrombus><Time><Tissues><Tomodensitometry><Training><Transthoracic Echocardiography><Triad><Triad Acrylic Resin><Triad resin><United States Department of Veterans Affairs><United States Veterans Administration><Universities><Veterans Administration><Veterans Affairs><Washington><Work><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><Zeugmatography><active followup><angiographic imaging><aorta aneurysm><aortic valve><aortic valve defect><aortic valve disease><aortic valve disorder><aortic valve replacement><aortic valvular disease><associate faculty><associate professor><biomechanical><biomechanical engineering><blood loss><bovid><bovine><calcification><cardiovascular disorder><career><catscan><circulatory system><clinical imaging><clinical investigation><computational modeling><computational models><computational simulation><computed axial tomography><computer based models><computer based prediction><computer tomography><computerized axial tomography><computerized modeling><computerized simulation><computerized tomography><cow><death risk><enroll><fluid><follow up><follow-up><followed up><followup><forecasting risk><heart output><heart sonography><heavy metal Pb><heavy metal lead><hemodynamics><high risk><implantation><improved><interventional strategy><liquid><mechanical><mid-career faculty><midcareer faculty><mortality risk><multidisciplinary><non-contrast CT><noncontrast CT><noncontrast computed tomography><patient oriented research><patient oriented study><porcine><prediction model><predictive modeling><prevent><preventing><professor><prospective><recruit><research and development><risk prediction><shear stress><simulation><skills><suid><surgery><thrombotic disease><thrombotic disorder><trial regimen><trial treatment>
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Behnaz Jarrahi

STANFORD UNIVERSITY, STANFORD, CA

Exploratory lead · 8/100
Career award
$175,889
FY 2024

Project Title

Multivariate Machine Learning to Characterize Opioid-induced Alterations in the Brain in Chronic Pain

Grant Number:

5K25DA048179-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/1/2020

End Date:

6/30/2025

Project Abstract

PROJECT SUMMARY/ABSTRACT Prescription opioids are a potent class of drugs for treating pain. However, growing body of research has described iatrogenic consequences of long-term (> 90 days) opioid use in patients with chronic pain including hyperalgesia and impaired executive function. Dopamine is a...

Research Terms

<Address><Affect><American><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Analgesia Tests><Anterior><Award><Behavior><Behavioral><Brain><Brain Nervous System><Caring><Central Lobe><Chronic><Chronic low back pain><Clinical><Clinical Trials><Cognitive><Corpus Striatum><Corpus striatum structure><D1 receptor><D2 receptor><DRD2 Receptor><Data><Data Analyses><Data Analysis><Decision Making><Development><Dopamine><Dopamine D1 Receptor><Dopamine D2 Receptor><Drug usage><Drugs><Encephalon><Epidemic><Epidemiologist><Epidemiology><Executive Dysfunction><Executive Function Deficit><Executive Impairment><Faculty><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Future><Goals><Health><Hydroxytyramine><Hyperalgesia><Hyperalgesic Sensations><Iatrogenesis><Imaging Procedures><Imaging Technics><Imaging Techniques><Immediate Memory><Infrastructure><Insula><Insula of Reil><Investigation><Investigators><Island of Reil><Link><Long-Term Effects><Longterm Effects><MR Imaging><MR Tomography><MRI><MRI Scans><MRIs><Machine Learning><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Measures><Mediating><Medical><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Mentors><Molecular><Morphology><Multimodal Imaging><NIDA><NMR Imaging><NMR Tomography><National Institute of Drug Abuse><National Institute on Drug Abuse><Nerve Impulse Transmission><Nerve Transmission><Neuronal Transmission><Neuropsychologic Tests><Neuropsychological Tests><Neuropsychologies><Neuropsychology><Nociception Tests><Nuclear Magnetic Resonance Imaging><Nucleus Accumbens><Opiate Addiction><Opiate Dependence><Opiates><Opioid><Opioid Analgesics><PET><PET Scan><PET imaging><PETSCAN><PETT><Pain><Pain Assessment><Pain Control><Pain Measurement><Pain Research><Pain Therapy><Pain management><Pain measure><Painful><Patient Self-Report><Patients><Pattern><Pharmaceutical Preparations><Play><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Prefrontal Cortex><Prevalence><Principal Investigator><Psyche structure><Psychophysics><Questionnaires><R-Series Research Projects><R01 Mechanism><R01 Program><Raclopride><Rad.-PET><Recovery><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Resolution><Rest><Rewards><Role><Self-Report><Sensory><Short-Term Memory><Shortterm Memory><Societies><Specialist><Strategic Planning><Striate Body><Striatum><Structure><Substance Use Disorder><Substance abuse problem><Symptoms><System><Techniques><Testing><Thick><Thickness><Time><Training><Zeugmatography><abuse liability><abuse of substances><abuse potential><addiction><addictive disorder><amygdaloid nuclear complex><axon signaling><axon-glial signaling><axonal signaling><brain circuitry><brain morphology><chronic pain><chronic pain condition><chronic pain disorder><chronic pain patient><chronic painful condition><classification algorithm><clinical applicability><clinical application><cognitive control><cognitive function><cognitive performance><cognitive process><cohort><data interpretation><data modeling><developmental><dopamine system><drug use><drug/agent><epidemiologic><epidemiological><executive control><executive function><experience><fMRI><flexibility><flexible><glia signaling><glial signaling><gray matter><hyperalgia><iatrogenic><iatrogenically><iatrogenicity><imaging scientist><innovate><innovation><innovative><licit opioid><machine based learning><machine learning based classifier><machine learning classifier><mental><model of data><model the data><modeling of the data><multi-modal imaging><multi-modal neuro-imaging><multi-modal neuroimaging><multi-modality imaging><multimodal neuro-imaging><multimodal neuroimaging><multimodality imaging><nerve signaling><neural><neural imaging><neural signaling><neuro-imaging><neuroimaging><neurological imaging><neuronal signaling><neuropsychologic><neurotransmission><opiate analgesia><opiate analgesic><opiate consumption><opiate drug use><opiate intake><opiate medication><opiate pain medication><opiate pain reliever><opiate therapy><opiate use><opioid addiction><opioid analgesia><opioid anesthetic><opioid consumption><opioid dependence><opioid dependent><opioid drug use><opioid intake><opioid medication><opioid pain medication><opioid pain reliever><opioid painkiller><opioid tapering><opioid therapy><opioid use><pain assay><pain patient><pain processing><pain treatment><patient centered><patient oriented><patient with chronic pain><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><prescribed opiate><prescribed opioid><prescription opiate><prescription opioid><psychophysical><receptor binding><receptor bound><recruit><resolutions><response><responsible research conduct><risk mitigation><skills><social role><striatal><substance abuse><substance use><substance use and disorder><substance using><substantia grisea><tool><working memory>
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Elaheh Rahbar

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Exploratory lead · 8/100
Career award
$164,292
FY 2021

Project Title

An Integrated Investigation of the Interaction Between PUFAs and Genetic Variants in Trauma and Critical Care

Grant Number:

5K25HL133611-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/15/2017

End Date:

6/30/2022

Project Abstract

Project Summary Elaheh Rahbar, PhD is requesting 5 years of didactic quantitative training under the supervision of Drs. Carl Langefeld, Floyd Chilton, Charles McCall and D. Clark Files. Primary reasons for this early career transition award include: i) PI was hired as an Assistant Professor in the...

Research Terms

<13q><ARDS><Acute><Acute Respiratory Distress><Acute Respiratory Distress Syndrome><Adjuvant><Adult ARDS><Adult RDS><Adult Respiratory Distress Syndrome><Affect><Age><Alleles><Allelomorphs><Area><Attenuated><Biological><Biological Markers><Business-Friendly Atmosphere><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Career Transition Award><Chromosome 11><Chromosome 13 Distal Arm><Chromosome 13 Long Arm><Clinical><Clinical Research><Clinical Study><Clinical Trials><Clotting><Coagulation><Coagulation Process><Complex><Confounding Factors (Epidemiology)><Confounding Variables><Critical Care><Critical Illness><Critically Ill><Da Nang Lung><Data><Data Banks><Data Set><Databanks><Dataset><Development and Research><Diet><Dietary Intervention><Doctor of Philosophy><Dysfunction><Enrollment><Enteral><Enteric><Environment><Epidemiologic Confounding Factor><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Fatty Acid Desaturases><Fatty Acid Desaturating Enzymes><Fatty Acid Metabolism Pathway><Fatty Acids><Functional disorder><Funding><Futility><Future><Gene Cluster><Gene variant><Generations><Genes><Genetic><Genetic Diversity><Genetic Variation><Genomics><Genotype><Glues><Goals><Grant><Immune response><Immunological response><Individual><Inflammation><Inflammation Mediators><Inflammatory><Inflammatory Response><Injury><Intervention><Intervention Strategies><Investigation><Investigators><K-Awards><K-Series Research Career Programs><Knowledge><Lipid Biochemistry><Lipids><MOF syndrome><Math><Math Models><Mathematics><Mediating><Mentors><Mentorship><Metabolic><Methods><Minor><Modeling><Morbidity><Morbidity - disease rate><Multiple Organ Dysfunction Syndrome><Multiple Organ Failure><N-3 polyunsaturated fatty acid><NIGMS><NIH><National Institute of General Medical Sciences><National Institutes of Health><Nature><Nutrition Interventions><Nutritional Interventions><Omega-3 Fatty Acids><Omega-3 PUFA><Omega-3 Polyunsaturated Fatty Acid><Omega3><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Ph.D.><PhD><Pharmacology><Phenotype><Physiologic><Physiological><Physiopathology><Play><Polyunsaturated Fatty Acids><Population><Probabilistic Models><Probability Models><R & D><R&D><Randomized Clinical Trials><Regulation><Research><Research Career Program><Research Personnel><Research Specimen><Researchers><Role><Sepsis><Shock Lung><Specimen><Statistical Models><Stiff lung><Supercomputing><Supervision><Techniques><Testing><Training><Trauma><Trauma Research><Trauma patient><Traumatic injury><United States National Institutes of Health><Variant><Variation><ages><allele variant><allelic variant><bio-markers><biologic marker><biomarker><blood infection><bloodstream infection><business-friendly environment><career><career development><cohort><collaborative atmosphere><collaborative environment><critical injury><data depository><data repository><design><designing><devastating injury><diet intervention><diet supplement><dietary><dietary supplements><diets><enroll><epigenetic variation><fat metabolism><fatty acid metabolism><fatty acid supplementation><forest><genetic variant><genomic variant><genomic variation><host response><immune system response><immunoresponse><improved><inflammatory mediator><injuries><injury response><innovate><innovation><innovative><insight><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><interventional strategy><lipid metabolism><mathematic model><mathematical model><mathematical modeling><metabolism measurement><metabolomics><metabonomics><mortality><multiorgan failure><multiple organ system failure><n-3 Fatty Acids><n-3 PUFA><n-3-PUFA><novel><nutrigenomics><nutrition><nutritional genomics><nutritional supplement><omega-3><pathophysiology><peer-group atmosphere><peer-group environment><precision medicine><precision-based medicine><professor><research and development><response><response to injury><severe injury><social role><statistical linear mixed models><statistical linear models><success><super computing><supplementation with fatty acids><systemic inflammation><systemic inflammatory response><thrombogenesis><thrombogenicity><trauma care><wet lung><ω-3 fatty acids><ω3 supplements>
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Devatha P. Nair

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Exploratory lead · 8/100
Career award
$164,006
FY 2022

Project Title

On Demand Removal of Oral Biofilms via Photresponsive Coatings

Grant Number:

5K25DE027418-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/1/2018

End Date:

6/30/2024

Project Abstract

CANDIDATE: Devatha P. Nair, Ph.D., is an Assistant Professor and a materials science researcher in the School of Dental Medicine at the University of Colorado-Anschutz Medical Campus. Dr. Nair’s K25 application proposes to engineer a photo-responsive coating that can enable ‘on-demand’ oral biofilm ...

Research Terms

<2-Propenoic acid, 2-methyl-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) ester><Abscission><Actinic Rays><Adhesions><Affect><Anti-Bacterial Agents><Anti-Infective Agents><Anti-Infective Drugs><Anti-Infectives><Anti-infective Preparation><AntiInfective Drugs><AntiInfectives><Antibacterial Agents><Antiinfective Agents><Area><Aspiration Pneumonia><Bacterial Adhesion><Behavior><Biocompatible Materials><Biomaterials><Biomedical Research><Bioreactors><Buccal Cavity><Buccal Cavity Head and Neck><Cardiovascular Diseases><Caries><Cause of Death><Cavitas Oris><Colorado><Consult><Dental><Dental Decay><Dental Enamel><Dental Plaque><Dental Restorations><Dental Schools><Dental Students><Dental caries><Development><Development Plans><Doctor of Philosophy><EXTMR><Educational process of instructing><Enamel><Engineering><Ensure><Environment><Esthetics><Excision><Exposure to><Extirpation><Extramural><Extramural Activities><Faculty><Failure><Fatigue><Funding><Generalized Growth><Gingiva><Gingival><Goals><Growth><Home><Home Care><Hospital Infections><Hospital acquired infection><Human><Image><Immunology><International><Investigators><Journals><Lack of Energy><Light><Magazine><Mechanics><Medical><Medicine><Mentors><Methacrylates><Microbial Biofilms><Microbiology><Modeling><Modern Man><Molecular Configuration><Molecular Conformation><Molecular Stereochemistry><Montana><Mouth><NIH><National Institutes of Health><Nosocomial Infections><Oral cavity><P aeruginosa><P. aeruginosa><Pathologic><Pattern><Performance><Ph.D.><PhD><Photoradiation><Polymers><Pregnancy Complications><Prevention><Pseudomonas aeruginosa><Pseudomonas pyocyanea><R-Series Research Projects><R01 Mechanism><R01 Program><Regimen><Removal><Research><Research Activity><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Training><Researchers><Residual><Residual state><Resistance><Risk><Saliva><Scheme><Scientist><Series><Stress><Structure><Surface><Surgical Removal><Systemic disease><TEGDMA><TEGMA><Teaching><Texture><Tissue Growth><Tooth><Tooth structure><Training><UV light><UV radiation><UV rays><Ultraviolet Rays><United States National Institutes of Health><Universities><Visible Light><Visible Light Radiation><Visible Radiation><Work><anti-bacterial><antibacterial><azobenzene><base><biocompatibility><biofilm><biological material><biomaterial compatibility><cardiovascular disorder><career development><cariogenic biofilm><cis trans isomerization><combat><communicable disease control agent><complications during pregnancy><composite restoration><conformation><conformational state><controlled release><dental biofilm><design><designing><developmental><imaging><institutional infection><materials science><mechanical><mechanical behavior><meetings><microbioreactor><microorganism><new approaches><non-Native><nonnative><novel approaches><novel strategies><novel strategy><ontogeny><oral biofilm><oral care><patient home care><patient homecare><phase change><photopolymerization><plaque biofilm><pregnancy-related complications><prevent><preventing><professor><programs><resection><resistant><response><restoration><restorative composite><restorative dentistry><restorative material><skill acquisition><skill development><skills><teeth><tenure process><tenure track><tooth decay><tooth enamel><triethylene glycol dimethacrylate><triethyleneglycol dimethacrylate><trioxyethylene dimethacrylate><ultra violet light><ultra violet radiation><ultra violet rays><ultraviolet light><ultraviolet radiation>
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Kan Shao

TRUSTEES OF INDIANA UNIVERSITY, BLOOMINGTON, IN

Exploratory lead · 8/100
Career award
$152,688
FY 2024

Project Title

Quantitative dose-response characterization for liver carcinogenicity with non-mutagenic modes of action

Grant Number:

5K25ES030402-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/13/2020

End Date:

12/31/2024

Project Abstract

PROJECT SUMMARY The goal of this K25 Mentored Quantitative Research Development Award project is to allow the PI to obtain systematic training in toxicology and prepare the PI to become an independent investigator. A research project complement the proposal’s comprehensive career development plan th...

Research Terms

<2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin><2,3,7,8-Tetrachlorodibenzo-p-dioxin Receptors><AH Receptors><Aryl Hydrocarbon Receptor><Award><Benchmarking><Best Practice Analysis><Biological><Cancer Causing Agents><Carcinogens><Chemical Exposure><Chemicals><Complement><Complement Proteins><Data><Development Plans><Development and Research><Dioxin Receptors><Dose><Environmental Health><Environmental Health Science><Evaluation><Event><Genotoxins><Goals><Government><Guidelines><Health><Hepatocarcinogenesis><Human><Industry><Investigators><Learning><Liver><Liver Carcinogenesis><Lytotoxicity><Mediating><Mentors><Methodology><Methods><Modeling><Modern Man><Modernization><Mutagens><Nuclear Translocator><Oncogens><PPAR alpha><PPAR-α><PPARalpha><PPARα><Pathway interactions><Peroxisome Proliferator-Activated Receptor alpha><Peroxisome Proliferator-Activated Receptor α><Polyaromatic Hydrocarbon Receptors><Preventive Medicine><Publishing><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Proposals><Researchers><Risk Assessment><Risk Estimate><Risk Management><Rodent><Rodentia><Rodents Mammals><Science><Scientist><Series><Shapes><Source><TCDD><TCDD Receptors><Tetrachlorodibenzodioxin><Toxic effect><Toxicities><Toxicology><Training><Training Programs><Uncertainty><adverse consequence><adverse outcome><benchmark><biologic><cancer risk><carcinogenesis in the liver><carcinogenicity><career><career development><complementation><cytotoxicity><doubt><experience><genotoxic agent><hepatic body system><hepatic carcinogenesis><hepatic organ system><hepatocellular carcinogenesis><improved><in vivo><innovate><innovation><innovative><liver cancer pathogenesis><liver tumorigenesis><novel><oncogenic agent><pathway><preventative medicine><research and development><response><success><tool>
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Mirna El Khatib

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 8/100
Career award
$148,905
FY 2023

Project Title

Membrane Anchored-Probes for Sensing Analytes at the Cell Surface

Grant Number:

5K25HL145092-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/2/2019

End Date:

7/31/2025

Project Abstract

Project Summary. Mirna El Khatib is a synthetic organic chemist, whose goal is to transition into the area of biomedical imaging with applications in cancer biology. An NHLBI K25 award will help her to accomplish this transition and simultaneously will lead to exploration and development of a new cl...

Research Terms

<2-photon><Affect><Amendment><Area><Award><Benign><Blood Precursor Cell><Bone Marrow><Bone Marrow Reticuloendothelial System><Calibration><Cancer Biology><Cell Body><Cell Culture Techniques><Cell Cycle><Cell Division Cycle><Cell Growth in Number><Cell Multiplication><Cell Proliferation><Cell Survival><Cell Viability><Cell membrane><Cell surface><Cells><Cellular Proliferation><Cessation of life><Cytoplasmic Membrane><Darkness><Death><Development><Disease Progression><Drops><Elements><Endocytosis><Environment><Environmental Factor><Environmental Risk Factor><Extracellular Space><Foundations><Goals><HSC transplantation><Hematopoietic Progenitor Cells><Hematopoietic Stem Cell Transplant><Hematopoietic Stem Cell Transplantation><Hematopoietic stem cells><Hydrophobicity><Image><Imaging technology><In Vitro><Intercellular Space><Investigators><Label><Laboratories><Learning><Leukemic Cell><Location><Malignant><Malignant - descriptor><Measurement><Measures><Membrane><Metalloporphyrins><Methods><Micro RNA><MicroRNAs><Microscopy><Modification><Molecular><Molecular Probes><Monitor><NHLBI><National Heart, Lung, and Blood Institute><Nutrient><O element><O2 element><Oxygen><Oxygen Consumption><Phase><Phototoxicity><Plasma Membrane><Play><Porphyrins><Predisposition><Progenitor Cells><Proliferating><Property><R-Series Research Projects><R01 Mechanism><R01 Program><Recurrence><Recurrent><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Resistance><Role><Signaling Molecule><Solid><Specificity><Susceptibility><Tail><Time><Toxic effect><Toxicities><Training><arm><biological research><biomedical imaging><blood stem cell><cell culture><cell cultures><cell imaging><cellular imaging><chemotherapy><design><designing><developmental><effective therapy><effective treatment><environmental risk><experiment><experimental research><experimental study><experiments><extracellular><hematopoietic progenitor><hematopoietic stem cell fate><hematopoietic stem progenitor cell><hemopoietic progenitor><hemopoietic stem cell><hydrophilicity><imaging><imaging probe><improved><in vivo><interest><leukemia><leukemic stem cell><leukemic transformation><longitudinal imaging><membrane structure><membrane synthesis><miRNA><miRNAs><phosphorescence><plasmalemma><pre-clinical research><preclinical research><prevent><preventing><quantitative imaging><resistant><sensor><serial imaging><skills><social role><stem cell niche><stem cells><synthetic DNA><synthetic construct><therapeutic outcome><therapy outcome><tool><two-photon>
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Robert J Dawe

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Exploratory lead · 8/100
Career award
$144,491
FY 2022

Project Title

Quantifying Lower Extremity Joint Motion in Community-Dwelling Older Adults to Elucidate its Contributions to Mobility Limitations, Incident Mobility Disability, and Falls

Grant Number:

5K25AG061254-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2019

End Date:

3/9/2023

Project Abstract

ABSTRACT This resubmitted application responds to PA-18-396 Mentored Quantitative Research Development Award (Parent K25). The overall goal of the proposal is to provide support and protected time for supervised research and study to supplement Dr. Robert Dawe’s strong quantitative background as a ...

Research Terms

<21+ years old><3-D><3-Dimensional><3D><AD dementia><Adult><Adult Human><Advisory Committees><Aging><Alzheimer><Alzheimer Type Dementia><Alzheimer disease><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's disease dementia><Alzheimers Dementia><Alzheimers disease><Anatomic><Anatomic Sites><Anatomic structures><Anatomical Sciences><Anatomy><Area><Autopsy><Award><Behavior><Biology of Aging><Biomedical Engineering><Brain><Brain Nervous System><Brain imaging><Characteristics><Clinic><Clinical><Clinical Data><Communities><Complex><Data><Development><Development and Research><Devices><Dimensions><Dysfunction><Early identification><Elderly><Emergent Technologies><Emerging Technologies><Encephalon><Equilibrium><Faculty><Functional disorder><Funding><Gait><Generalized Growth><Goals><Growth><Health><Hip Joint><Histopathology><Impairment><Individual><Intervention><Intervention Strategies><Investigators><Joints><Knee joint><Knowledge><Laboratories><Life><Link><Location><Lower Extremity><Lower Limb><Measurement><Measures><Membrum inferius><Memory><Mentors><Modeling><Monitor><Motion><Motor><Movement><Musculoskeletal Diseases><NIH><National Institutes of Health><Nervous System Diseases><Neurobiology><Neurologic Disorders><Neurological Disorders><Paper><Parents><Participant><Pathologic><Pathologist><Patient Self-Report><Phenotype><Physical activity><Physicians><Physiopathology><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Primary Senile Degenerative Dementia><Psychometrics><R & D><R&D><Reading><Research><Research Personnel><Researchers><Risk><Rotation><Screening procedure><Self-Report><Specialty><Structure><Supervision><Task Forces><Techniques><Technology><Testing><Time><Tissue Growth><Training><Training Programs><Travel><United States National Institutes of Health><Volition><Work><actigraph><actigraphy><active life style><active lifestyle><active living><adulthood><advanced age><advisory team><age dependent><age related><balance><balance function><base><bio-engineered><bio-engineers><bioengineering><biological engineering><biological systems><body movement><brain visualization><career development><clinical phenotype><community setting><conference><convention><cost effective><dementia of the Alzheimer type><developmental><disability><elders><experience><falls><geriatric><instrument><interventional strategy><joint function><late life><later life><medical specialties><meetings><musculoskeletal disorder><necropsy><nervous system disorder><neurobiological><neurological disease><neuropathology><new technology><novel><novel technologies><older adult><older person><ontogeny><pathophysiology><portability><postmortem><primary degenerative dementia><public health priorities><public health relevance><research and development><research study><screening tools><senile dementia of the Alzheimer type><senior citizen><sensor><skills><success><summit><symposia><symposium><three dimensional>
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Akane Sano

RICE UNIVERSITY, HOUSTON, TX

Exploratory lead · 8/100
Career award
$143,654
FY 2023

Project Title

Using moment-to-moment sensors, mobile technology, and stimulated cytokine responses to identify physical and mental health risk among Alzheimer's spousal caregivers

Grant Number:

5K25AG070306-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/5/2021

End Date:

5/31/2025

Project Abstract

ABSTRACT The proposed three-year K25 will launch Dr. Akane Sano’s independent research career in the field of aging and physical and mental health where she will endeavor to identify physical and mental health disease risks; understand the role of physiological and behavioral factors in physical and...

Research Terms

<21+ years old><AD dementia><AD related dementia><ADRD><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's care><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease care><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's patient><Alzheimers Dementia><Amentia><Atrophic Arthritis><Award><Bayesian Analysis><Bayesian Modeling><Bayesian adaptive designs><Bayesian adaptive models><Bayesian belief network><Bayesian belief updating model><Bayesian computation><Bayesian framework><Bayesian hierarchical model><Bayesian inference><Bayesian network analysis><Bayesian network model><Bayesian nonparametric models><Bayesian spatial analysis><Bayesian spatial data model><Bayesian spatial image models><Bayesian spatial models><Bayesian statistical analysis><Bayesian statistical inference><Bayesian statistical models><Bayesian statistics><Bayesian tracking algorithms><Behavior><Behavioral><Biological><Biological Markers><Blood Sample><Blood specimen><Cancers><Cardiac Chronotropism><Cardiovascular Diseases><Care Givers><Caregivers><Cell Phone><Cellular Phone><Cellular Telephone><Chronic><Circadian Rhythms><Coping Skills><Coupling><Data><Data Analyses><Data Analysis><Data Science><Dementia><Dementia caregivers><Development><Disease><Disorder><Elderly><Electrodermal Response><Engineering><Evidence based intervention><Galvanic Skin Response><Health><Health Care Technology><Health Technology><Healthcare Technology><Heart Rate><Human><In Situ><Individual><Inflammation><Inflammatory><Intervention><Intervention Strategies><Interview><Investigators><Ketosis-Resistant Diabetes Mellitus><Knowledge><Learning><Longitudinal Studies><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Measurement><Measures><Mental Health><Mental Hygiene><Mentors><Mentorship><Methods><Mobile Phones><Modeling><Modern Man><Monitor><Moods><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nyctohemeral Rhythm><Osteoporosis><Outcome><Parents><Participant><Patient Self-Report><Persons><Phenotype><Physical activity><Physiologic><Physiological><Physiology><Population><Predisposition><Premature Aging><Premature aging syndrome><Primary Senile Degenerative Dementia><Process><Production><Psychogalvanic Reflex><Psychological Health><Psychoneuroimmunology><Public Health><QOL><Quality of life><Questionnaires><Research><Research Design><Research Personnel><Researchers><Rheumatoid Arthritis><Risk><Risk Factors><Role><Science><Scientist><Self-Report><Skin Electric Conductance><Sleep><Slow-Onset Diabetes Mellitus><Spouse Caregiver><Stable Diabetes Mellitus><Stress><Stress and Coping><Structure><Study Type><Susceptibility><Symptoms><System><T2 DM><T2D><T2DM><Testing><Time><Training><Twenty-Four Hour Rhythm><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><adaptive intervention><adult onset diabetes><adulthood><advanced age><age dependent><age related><behavior response><behavioral response><bio-markers><biobehavior><biobehavioral><biologic><biologic marker><biomarker><body sensor><body worn sensor><build resilience><build resiliency><cardiovascular disorder><care giver stress><care giving><care giving burden><career><caregiver stress><caregivers for persons living with dementia><caregivers for persons with dementia><caregivers of individuals with dementia><caregivers of patients with dementia><caregiving><caregiving burden><caregiving stress><circadian process><clinical significance><clinically significant><coping strategy><coping with stress><cost><cytokine><daily biorhythm><data interpretation><dementia care giver><design><designing><develop resilience><develop resiliency><developmental><digital><disease risk><disorder risk><e-Health><eHealth><elders><electronic health><enhance resilience><enhance resiliency><experience><geriatric><handheld mobile device><health data><high risk><iPhone><improve resilience><improve resiliency><increase resilience><increase resiliency><inflammation marker><inflammatory marker><innovate><innovation><innovative><intervention design><interventional strategy><ketosis resistant diabetes><late life><later life><long-term study><longitudinal design><longitudinal outcome studies><longterm study><m-Health><mHealth><malignancy><maturity onset diabetes><methods to study multiple-level influences><mobile computing><mobile device><mobile health><mobile platform><mobile sensing><mobile sensor><mobile technology><mortality><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><neoplasm/cancer><novel><older adult><older person><parent><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><physical conditioning><physical health><physiologic model><portable sensor><preference><prevent><preventing><primary degenerative dementia><promote resilience><promote resiliency><protective factors><psychologic><psychological><psychoneuroimmunological><research study><resilience development><response><rheumatic arthritis><senile dementia of the Alzheimer type><senior citizen><sensing technology><sensor><sensor technology><skills><skin conductance><smart phone><smartphone><social role><spousal care giver><spousal caregiver><spouse care giver><stress reduction><study design><tech development><technology development><therapy design><tool><treatment design><type 2 DM><type II DM><type two diabetes><wearable biosensor><wearable device><wearable electronics><wearable sensor><wearable sensor technology><wearable system><wearable technology><wearable tool><wearables>
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ATILLA GONENC

MCLEAN HOSPITAL, BELMONT, MA

Exploratory lead · 8/100
Career award
$141,897
FY 2021

Project Title

Assessing the Impact of Cannabis Use on the Brain

Grant Number:

5K25DA045954-03

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/15/2019

End Date:

12/2/2022

Project Abstract

ABSTRACT This application requests 3 years of funding through the K25 Mentored Quantitative Research Scientist Development Award mechanism. With a Ph.D. degree in physics, the candidate proposes to receive additional training in neurocognitive and pharmacological aspects of chronic substance use to ...

Research Terms

<12-20 years old><9-ene-Tetrahydrocannabinol><Active Oxygen><Address><Adolescence><Age><Anterior><Antioxidants><Award><Biological Markers><Brain><Brain Nervous System><Brain imaging><Cannabis><Causality><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cellular injury><Chemical Dependence><Chronic><Clinical><Cognition><Cognitive><Cognitive Science><D.C. Washington><DC Washington><Data><Delta-9-Tetrahydrocannabinol><Dependence><Dimensions><District of Columbia><Doctor of Philosophy><Drug Addiction><Drug Dependence><Drug Dependency><Drug abuse><Dysfunction><Education><Educational aspects><Elderly><Elements><Encephalon><Enrollment><Equilibrium><Etiology><Exhibits><Functional disorder><Funding><Geographic state><Glutathione><Goals><H+ element><Health><Hydrogen Ions><Image><Individual><International><Intracellular Communication and Signaling><Investigation><K01 Award><K01 Mechanism><K01 Program><Knowledge><Laboratories><Laws><Lead><Legal><Length of Life><Longevity><MR Spectroscopy><Magnetic Resonance Spectroscopy><Maintenance><Measures><Medical Marijuana><Medicinal Marijuana><Mental disorders><Mental health disorders><Mentored Research Scientist Development Award><Mentored Training Award><Mentors><Methods><NIH RFA><Nerve Transmitter Substances><Neurobiology><Neurocognitive><Neuropsychologies><Neuropsychology><Neurotransmitters><Oxidative Stress><Oxygen Radicals><Pb element><Ph.D.><PhD><Pharmacology><Physics><Physiopathology><Population><Prevalence><Pro-Oxidants><Process><Protocol><Protocols documentation><Protons><Psychiatric Disease><Psychiatric Disorder><Psychopathology><Public Health><Reactive Oxygen Species><Relaxation><Reporting><Request for Applications><Research><Research Resources><Research Scientist Development Award><Resources><Risk Factors><Role><Schedule><Signal Transduction><Signal Transduction Systems><Signaling><Smoke><Substance Addiction><Substance Dependence><Substance abuse problem><Suggestion><Supervision><Survey Instrument><Surveys><Symptoms><THC co-use><THC use><Testing><Tetrahydrocannabinol><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Time><Tobacco><Toxic effect><Toxicities><Training><US State><United States><Visit><Vulnerable Populations><Work><Writing><abnormal psychology><abuse of drugs><abuse of substances><abuses drugs><adolescence (12-20)><adult youth><advanced age><aged><ages><anti-oxidant><balance><balance function><bio-markers><biologic marker><biological signal transduction><biomarker><brain visualization><cannabis use><cannabis use disorder><cannabis user><career><career development><causation><cell damage><cell injury><cellular damage><cingulate cortex><clinical diagnostics><cognitive performance><cognitive psychology><damage to cells><delta(1)-THC><delta(1)-Tetrahydrocannabinol><delta(9)-THC><delta(9)-Tetrahydrocannabinol><design><designing><disease causation><drug development><elders><enroll><executive control><executive function><experience><experiment><experimental research><experimental study><frontal cortex><frontal lobe><gamma-L-Glu-L-Cys-Gly><gamma-L-Glutamyl-L-Cysteinylglycine><geriatric><heavy metal Pb><heavy metal lead><human subject><imaging><improved><injury to cells><instrument><late life><later life><life span><lifespan><marijuana use><marijuana use disorder><marijuana user><medical cannabis><medicinal cannabis><meetings><mental illness><multi-modality><multidisciplinary><multimodality><neuro-imaging><neurobiological><neurobiological mechanism><neuroimaging><neuropsychologic><new drug target><new druggable target><new pharmacotherapy target><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutic target><new therapy approaches><new therapy target><novel><novel drug target><novel druggable target><novel imaging technique><novel pharmacotherapy target><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutic target><novel therapy approach><novel therapy target><older adult><older person><pathophysiology><potential biological marker><potential biomarker><programs><psychiatric illness><psychological disorder><senior citizen><sex><skills><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><substance abuse><substance use><substance using><therapeutic cannabis><therapeutic marijuana><virtual><vulnerable group><young adult><young adulthood><Δ(1)-THC><Δ(1)-tetrahydrocannabinol><Δ(9)-THC><Δ(9)-tetrahydrocannabinol><Δ-9-tetrahydrocannabinol><Δ9-tetrahydrocannabinol>
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Ashley Weaver

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Exploratory lead · 8/100
Career award
$133,036
FY 2023

Project Title

Effect of protein supplementation during weight loss on older adult bone health

Grant Number:

5K25AG058804-05

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/15/2019

End Date:

11/30/2024

Project Abstract

Project Summary. Dr. Weaver seeks this K25 mentored training award to expand her bioengineering research background in medical imaging and finite element modeling of trauma towards pursuit of an independent research career focused on reducing osteoporosis and fracture in older adults. Weight loss po...

Research Terms

<3-D><3-Dimensional><3D><Active Follow-up><Adipocytes><Adipose Cell><Adipose tissue><Affect><Aging><American><Ancillary Study><Animal Model><Animal Models and Related Studies><Applications Grants><Assessment instrument><Assessment tool><Attenuated><Award><BMI><BMI percentile><BMI z-score><Biomedical Engineering><Body Composition><Body Weight decreased><Body mass index><Bone Density><Bone Marrow><Bone Marrow Reticuloendothelial System><Bone Mineral Density><Bone structure><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Carbohydrates><Classification><Clinical><Clinical Research><Clinical Study><Clinical Trials><Complement><Complement Proteins><Computed Tomography><Conduct Clinical Trials><Consumption><Coxa><DEXA><DXA><Data><Development><Development and Research><Diagnostic><Diet><Dietary Proteins><Drug Therapy><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Elderly><Elements><Engineering><Exercise><Fat Cells><Fatty Tissue><Femur><Fracture><Fracture due to osteoporosis><General Radiology><Geriatrics><Gerontology><Grant Proposals><Hip><Hip region structure><History><Image><Infrastructure><Intervention><Intervention Strategies><Investigators><K01 Award><K01 Mechanism><K01 Program><Knowledge><Lead><Leanness><Lipocytes><Low-Protein Diet><Mature Lipocyte><Mature fat cell><Measurement><Measures><Medical Imaging><Mentored Research Scientist Development Award><Mentored Training Award><Mentors><Modeling><Musculoskeletal><NIH><National Institutes of Health><Nutritional><Nutritional Science><Obesity><Osteoporosis><Osteoporosis prevention><Osteoporosis with fracture><Osteoporotic fracture><Outcome><Over weight><Overweight><Participant><Pb element><Persons><Pharmacotherapy><Phase><Phenotype><Physical Function><Population><Predicting Risk><Protein-Restricted Diet><Proteins><Quetelet index><R & D><R&D><Radiology><Radiology Specialty><Randomized><Recommendation><Recommended Dietary Allowance><Recording of previous events><Regulation><Research><Research Personnel><Research Resources><Research Scientist Development Award><Researchers><Resources><Risk><Scanning><Spinal Column><Spine><Supplementation><Systematics><Techniques><Testing><Thick><Thickness><Thinness><Tomodensitometry><Training><Trauma><United States National Institutes of Health><Vertebrae><Vertebral><Vertebral column><Weight><Weight Loss><Weight Reduction><Woman><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><active followup><adipose><adiposity><adult adiposity><adult obesity><adults with obesity><advanced age><attenuate><attenuates><backbone><bio-engineered><bio-engineers><bioengineering><biogerontology><biological engineering><body weight loss><bone><bone fracture><bone health><bone loss><bone mass><bone metabolism><bone preservation><bone quality><bone strength><career><catscan><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><corpulence><design><designing><developmental><diets><drug treatment><elders><experience><follow up><follow-up><followed up><followup><forecasting risk><forest><fracture risk><geriatric><geriatric medicine><heavy metal Pb><heavy metal lead><high risk><histories><imaging><improved><innovate><innovation><innovative><interventional strategy><late life><later life><medical college><medical schools><men><model of animal><multidisciplinary><non-contrast CT><noncontrast CT><noncontrast computed tomography><nutrition><nutrition science><nutritious><older adult><older person><osteoporosis associated fracture><osteoporosis related fracture><osteoporosis with pathological fracture><osteoprotection><osteoprotective><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><prevent><prevent osteoporosis><preventing><prognostic tool><protein intake><randomisation><randomization><randomly assigned><research and development><risk prediction><risk predictions><school of medicine><senior citizen><skeletal structure><spine bone structure><three dimensional><tool><translational study><weight maintenance><weights><white adipose tissue><wt-loss><yellow adipose tissue>
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Jillian Elizabeth Urban

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Exploratory lead · 8/100
Career award
$119,562
FY 2024

Project Title

Evidence-based intervention for Improved Head Impact Safety in Youth Football

Grant Number:

5K25HD101686-04

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/18/2021

End Date:

2/28/2025

Project Abstract

Project Summary Concussions in sports have received much focus recently; however, the consequences of non-concussive head impacts, more common and thus potentially more important, may have a greater influence on brain health in youth athletes. With ~ 3.5 million football players between ages 6 and 1...

Research Terms

<Address><Adopted><Age><Area><Attitude><Award><Awareness><Biomechanics><Brain><Brain Concussion><Brain Diseases><Brain Disorders><Brain Nervous System><Cerebral Concussion><Commotio Cerebri><Communities><Controlled Environment><Data><Data Collection><Degenerative Neurologic Disorders><Development><Development and Research><Effectiveness of Interventions><Encephalon><Encephalon Diseases><Epidemiology><Evaluation><Evidence based intervention><Evidence based practice><Exposure to><Feedback><Focus Groups><Football><Future><Goals><Guidelines><Health Sciences><Individual><Injury><Intervention><Intervention Strategies><Interview><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Knowledge><Lead><Leadership><Life><Link><Literature><Manufactured football><Measures><Mentors><Mentorship><Methodology><Methods><Modeling><Monitor><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Outcome><Parents><Pb element><Perception><Pilot Projects><Play><Policies><Position><Positioning Attribute><Predisposition><Preventative strategy><Prevention strategy><Preventive strategy><Process><Public Health><R & D><R&D><Regulation><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Safety><Seasons><Severities><Sports><Strategic Planning><Structure><Survey Instrument><Surveys><Susceptibility><Systems Theory><Testing><Training><Training Programs><Work><Youth><Youth 10-21><acceptability and feasibility><ages><artificial environment><biomechanical><brain health><collision sports><community engaged approach><community engaged approaches><community engaged strategies><community engaged strategy><community engagement><community partnered approach><community partnered strategy><concussion><concussive><contact sports><data integration><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><design><designing><develop therapy><developmental><effective intervention><engagement with communities><epidemiologic><epidemiological><evidence base><head impact><heavy metal Pb><heavy metal lead><high risk><implementation intervention><implementation process><implementation science><improved><injuries><injury prevention><intervention development><interventional strategy><junior high><junior high school><member><middle school><neurodegenerative illness><parent><participant retention><pilot study><pilot test><programs><recruit><research and development><sensor><skills><social><success><therapy development><timeline><treatment development>
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Jitao Zhang

WAYNE STATE UNIVERSITY, DETROIT, MI

Exploratory lead · 8/100
Career award
$114,021
FY 2023

Project Title

Optically mapping tissue biomechanics during neural tube closure

Grant Number:

5K25HD097288-06

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/1/2019

End Date:

7/31/2024

Project Abstract

Project Summary This project features the development of advanced photonic technology to attack a major unmet challenge in developmental biology. Embryonic morphogenesis results from a complex combination of gene expression, biochemical signaling, and biomechanics. While methods to evaluate the firs...

Research Terms

<3-D><3-Dimensional><3D><Address><Advanced Development><Affect><Apical><Atomic Force Microscopy><Award><Biochemical><Biological><Biology><Biomechanics><Biomedical Research><Biophysics><Birth Defects><Body Tissues><Calibration><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Complement><Complement Proteins><Complex><Congenital Abnormality><Congenital Anatomic Abnormality><Congenital Anatomical Abnormality><Congenital Defects><Congenital Deformity><Congenital Malformation><Cues><Data><Defect><Detection><Development><Developmental Biology><Developmental Diagnostic><Dorsal><Elastic Tissue><Elasticity><Embryo><Embryo Development><Embryogenesis><Embryonic><Embryonic Development><Embryonic Tissue><Ensure><Environmental Factor><Environmental Risk Factor><Event><Evolution><F-Actin><Failure><Filamentous Actin><Force Microscopy><Gases><Gene Combinations><Gene Expression><Genetic><Gestation><Goals><Grant><Hour><Human><Illumination><In Situ><Intracellular Communication and Signaling><Investigators><Knowledge><Lighting><Link><Maps><Measurement><Measures><Mechanics><Methods><Mice><Mice Mammals><Microscopic><Microscopy><Modeling><Modern Man><Modulus><Monitor><Morphogenesis><Morphology><Murine><Mus><Names><Neural Fold><Neural Tube Closure><Neural Tube Defects><Neural Tube Developmental Defects><Neural tube><Noise><Optics><Pattern><Phenotype><Pregnancy><Process><Property><Recovery><Regulation><Research><Research Personnel><Researchers><Resistance><Resolution><Role><Sample Size><Sampling><Scanning><Scanning Force Microscopy><Schistorrhachis><Science><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Speed><Spina Bifida><Spinal Dysraphia><Spinal Dysraphism><Techniques><Technology><Testing><Therapeutic><Time><Tissue Engineering><Tissues><Training><absorption><bioengineered tissue><biologic><biological signal transduction><biomechanical><biomechanical engineering><biophysical foundation><biophysical principles><biophysical sciences><cell behavior><cellular behavior><cleft spine><constriction><convergent extension><developmental><driving force><elastic imaging><elasticity imaging><elastography><embryo tissue><engineered tissue><environmental risk><hydrocele spinalis><image-based method><imaging method><imaging modality><improved><in vivo><innovate><innovation><innovative><instrument><light scattering><mechanic><mechanical><mechanical properties><mechanical stimulus><morphogenetic process><mutant mouse model><name><named><naming><neural><neural plate><novel><optical><photonics><rachischisis posterior><resistant><resolutions><skills><social role><tech development><technological research and development><technology development><technology implementation><technology research and development><technology validation><three dimensional><tissue map><tissue mapping>
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Elaheh Rahbar

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Exploratory lead · 8/100
Career award
$54,000
FY 2021

Project Title

An Integrated Investigation of the Interaction Between PUFAs and Genetic Variants in Trauma and Critical Care

Grant Number:

3K25HL133611-04S1

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2021

End Date:

2/28/2022

Project Abstract

Project Summary Elaheh Rahbar, PhD is requesting 5 years of didactic quantitative training under the supervision of Drs. Carl Langefeld, Floyd Chilton, Charles McCall and D. Clark Files. Primary reasons for this early career transition award include: i) PI was hired as an Assistant Professor in the...

Research Terms

<13q><ARDS><Acute><Acute Respiratory Distress><Acute Respiratory Distress Syndrome><Adjuvant><Adult ARDS><Adult RDS><Adult Respiratory Distress Syndrome><Affect><Age><Alleles><Allelomorphs><Area><Attenuated><Biological><Biological Markers><Business-Friendly Atmosphere><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Career Transition Award><Chromosome 11><Chromosome 13 Distal Arm><Chromosome 13 Long Arm><Clinical><Clinical Research><Clinical Study><Clinical Trials><Clotting><Coagulation><Coagulation Process><Complex><Confounding Factors (Epidemiology)><Confounding Variables><Critical Care><Critical Illness><Critically Ill><Da Nang Lung><Data><Data Banks><Data Set><Databanks><Dataset><Development and Research><Diet><Dietary Intervention><Doctor of Philosophy><Dysfunction><Enrollment><Enteral><Enteric><Environment><Epidemiologic Confounding Factor><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Fatty Acid Desaturases><Fatty Acid Desaturating Enzymes><Fatty Acid Metabolism Pathway><Fatty Acids><Functional disorder><Funding><Futility><Future><Gene Cluster><Gene variant><Generations><Genes><Genetic><Genetic Diversity><Genetic Variation><Genomics><Genotype><Glues><Goals><Grant><Immune response><Immunological response><Individual><Inflammation><Inflammation Mediators><Inflammatory><Inflammatory Response><Injury><Intervention><Intervention Strategies><Investigation><Investigators><K-Awards><K-Series Research Career Programs><Knowledge><Lipid Biochemistry><Lipids><MOF syndrome><Math><Math Models><Mathematics><Mediating><Mentors><Mentorship><Metabolic><Methods><Minor><Modeling><Morbidity><Morbidity - disease rate><Multiple Organ Dysfunction Syndrome><Multiple Organ Failure><N-3 polyunsaturated fatty acid><NIGMS><NIH><National Institute of General Medical Sciences><National Institutes of Health><Nature><Nutrition Interventions><Nutritional Interventions><Omega-3 Fatty Acids><Omega-3 PUFA><Omega-3 Polyunsaturated Fatty Acid><Omega3><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Ph.D.><PhD><Pharmacology><Phenotype><Physiologic><Physiological><Physiopathology><Play><Polyunsaturated Fatty Acids><Population><Probabilistic Models><Probability Models><R & D><R&D><Randomized Clinical Trials><Regulation><Research><Research Career Program><Research Personnel><Research Specimen><Researchers><Role><Sepsis><Shock Lung><Specimen><Statistical Models><Stiff lung><Supercomputing><Supervision><Techniques><Testing><Training><Trauma><Trauma Research><Trauma patient><Traumatic injury><United States National Institutes of Health><Variant><Variation><ages><allele variant><allelic variant><bio-markers><biologic marker><biomarker><blood infection><bloodstream infection><business-friendly environment><career><career development><cohort><collaborative atmosphere><collaborative environment><critical injury><data depository><data repository><design><designing><devastating injury><diet intervention><diet supplement><dietary><dietary supplements><diets><enroll><epigenetic variation><fat metabolism><fatty acid metabolism><fatty acid supplementation><forest><genetic variant><genomic variant><genomic variation><host response><immune system response><immunoresponse><improved><inflammatory mediator><injuries><injury response><innovate><innovation><innovative><insight><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><interventional strategy><lipid metabolism><mathematic model><mathematical model><mathematical modeling><metabolism measurement><metabolomics><metabonomics><mortality><multiorgan failure><multiple organ system failure><n-3 Fatty Acids><n-3 PUFA><n-3-PUFA><novel><nutrigenomics><nutrition><nutritional genomics><nutritional supplement><omega-3><pathophysiology><peer-group atmosphere><peer-group environment><precision medicine><precision-based medicine><professor><research and development><response><response to injury><severe injury><social role><statistical linear mixed models><statistical linear models><success><super computing><supplementation with fatty acids><systemic inflammation><systemic inflammatory response><thrombogenesis><thrombogenicity><trauma care><wet lung><ω-3 fatty acids><ω3 supplements>
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Iris Yuwen Zhou

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 8/100
Career award
$52,899
FY 2023

Project Title

Quantitative MRI-PET Imaging of Pulmonary Fibrosis

Grant Number:

3K25HL148837-03S1

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/25/2020

End Date:

6/30/2024

Project Abstract

Abstract The administrative supplement will help the PI to maintain productivity while fulfilling her caregiving responsibilities and achieve the goal of the parent K25 project to develop and implement an MR-PET lung imaging tool to accurately quantify molecular abnormalities associated with pulmona...

Research Terms

<Administrative Supplement><Air><Animals><Artifacts><Binding><Biopsy><Blood Fractioning><Body Tissues><Cardiovascular Diseases><Cell Communication and Signaling><Cell Signaling><Chromosomal, Gene, or Protein Abnormality><Clinical><Clinical Trials><Collagen><Cytogenetic or Molecular Genetic Abnormality><Deposit><Deposition><Diagnosis><Disease><Disorder><Early Diagnosis><Fibrosing Alveolitis><Fibrosis><Fibrotic lesions in lung><Ga element><Gallium><Genetic Abnormality><Goals><H+ element><High Resolution Computed Tomography><Hydrogen Ions><Image><Imaging Device><Imaging Instrument><Imaging Tool><In-bleomycin><Intermediary Metabolism><Intracellular Communication and Signaling><Label><Lung><Lung Function Tests><Lung Respiratory System><Lung Tissue Fibrosis><Lung scar><Lung tissue scar><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic Processes><Metabolism><Methods><Molecular><Molecular Abnormality><Molecular Interaction><Monitor><Morphologic artifacts><Morphology><Motion><NMR Imaging><NMR Tomography><Nervous System Diseases><Neurologic Disorders><Neurological Disorders><Nuclear Magnetic Resonance Imaging><Oncology><Oncology Cancer><Outcome><PET><PET Scan><PET imaging><PETSCAN><PETT><Parents><Pathogenicity><Patient Care><Patient Care Delivery><Patients><Phase><Photons><Physiology><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Predisposition><Process><Productivity><Prognosis><Protons><Pulmonary Fibrosis><Pulmonary Scar><Pulmonary Tissue fibrosis><Pulmonary function tests><Pulmonary imaging><Rad.-PET><Rotation><Scarring at the lung><Scarring in the lung><Signal Transduction><Signal Transduction Systems><Signaling><Stable Disease><Susceptibility><Techniques><Time><Tissues><Variant><Variation><Zeugmatography><anatomic imaging><anatomical imaging><attenuation><biological signal transduction><blood fractionation><cardiovascular disorder><care giving><caregiving><contrast imaging><density><diffuse interstitial pulmonary fibrosis><drug development><early detection><fibrosis in the lung><fibrotic lung><first in man><first-in-human><high resolution CT><idiopathic pulmonary fibrosis><imaging><improved><in vivo><indium-bleomycin><injured><lung fibrosis><lung function><lung imaging><lung scanning><molecular aberrations><molecular imaging><molecule imaging><nervous system disorder><neurological disease><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><parent><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><pulmonary><pulmonary function><quantitative imaging><respiratory><response to therapy><response to treatment><simulation><therapeutic response><therapy response><treatment response><uptake>
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Liran Oren

UNIVERSITY OF CINCINNATI, CINCINNATI, OH

Exploratory lead · 8/100
Career award
$48,329
FY 2021

Project Title

Resonance and aeroacoustic relationship in velopharyngeal insufficiency

Grant Number:

3K25DC014755-05S1

Activity Code:

K25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2016

End Date:

1/31/2022

Project Abstract

Project Summary The goal of this K25 Mentored Quantitative Research Career Development Award is to enable the candidate to develop expertise in the areas of acoustics and aeroacoustics of speech, in the context of a research plan that investigates sound source mechanisms that affect speech disorders...

Research Terms

<Acoustic><Acoustics><Address><Advisory Committees><Affect><Air Movements><Area><Award><Bears><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Characteristics><Clinical><Clinical Management><Consensus><Craniofacial Abnormalities><Curriculum><Development Plans><Educational Curriculum><Educational workshop><Goals><Imaging Procedures><Imaging Technics><Imaging Techniques><Individual><Investigators><K-Awards><K-Series Research Career Programs><Knowledge><Medical Imaging><Mentors><Mentorship><Methodology><Modeling><Palatopharyngeal Incompetence><Research><Research Career Program><Research Personnel><Researchers><Severities><Source><Speech><Speech Disorders><Speech Manifestations><Structure><Supervision><Task Forces><Training><Ursidae><Ursidae Family><Velopharyngeal Insufficiency><Workshop><advisory team><air flow><airflow><bear><craniofacial anomalies><craniofacial defects><craniofacial malformation><design><designing><experience><innovate><innovation><innovative><lesson plans><multidisciplinary><sound>
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Search NIH grants by PI name

Looking for a specific principal investigator? The keyword search above looks up funded projects by topic. To search NIH grants by PI name (last name, first + last name, or partial name) and see every active and recent NIH award for that researcher, use the dedicated PI Funding Status tool.

How to Use PI Funding Data for Career Decisions

Finding the right principal investigator is one of the most important decisions in an academic career. Whether you are a postdoc looking for a mentor, a graduate student choosing a rotation lab, or a collaborator seeking a co-PI, NIH funding data provides objective signals about which investigators have active research programs and resources to support new team members.

A PI with a recently awarded R01 or equivalent grant is more likely to have budget for new personnel than one whose funding ended two years ago. The activity code tells you the type of grant: R01 and R35 awards typically support multiple lab members, while K-series awards are individual career development grants that may not fund additional positions. Understanding these distinctions helps you interpret search results accurately.

Look beyond the dollar amount. A $500,000 per year R01 at a high-cost institution may support fewer positions than a $300,000 award at a university with lower overhead rates. The project abstract and public health relevance statement reveal whether the PI's research direction aligns with your interests and expertise.

Understanding PI Grant Portfolios

A PI's grant portfolio reveals more than individual awards. Investigators with multiple active grants often run larger labs with more diverse projects, which can mean more opportunities for trainees. However, a PI with a single well-funded grant may offer more focused mentorship and a clearer path to publications.

Multi-PI grants (those with more than one principal investigator listed) indicate collaborative research and may involve trainees from multiple institutions. These can be excellent opportunities for interdisciplinary training but may also mean split attention from any single mentor.

Pay attention to the timing of awards. A PI who just received a new five-year R01 is in a different position than one whose grant ends next year. New awards often correspond to lab expansion and active recruiting, making them ideal targets for job seekers. The start and end dates shown in each result help you assess this timing.

Best Practices for Contacting Funded PIs

Once you identify a promising PI through this tool, the next step is outreach. NIH public records do not include email addresses, but you can usually find contact information through the PI's institutional profile page, lab website, or recent publications. Google Scholar, PubMed, and the PI's department website are reliable starting points.

When reaching out, reference the specific grant that caught your attention. Mentioning the project title and explaining how your skills relate to the funded work shows that you have done your homework. Keep your initial message concise: introduce yourself, explain your interest, attach your CV, and ask whether they anticipate openings.

Timing matters. Contacting a PI within the first year of a new award is ideal, as this is when they are most likely to be recruiting. If you find multiple promising PIs in the same field, prioritize those with the most recent award notices and activity codes that support trainee positions such as R01, U01, or P-series grants.

Frequently Asked Questions About PI Search

What does the opportunity score mean?

The opportunity score is a heuristic that combines award recency, funding amount, activity code type, and project characteristics to estimate how actionable a result might be for job seekers or collaborators. Higher scores suggest stronger signals, but always verify by reading the abstract and checking the PI's current lab page.

Why can't I find a PI I know has funding?

Name variations are the most common cause. Try searching with just the last name, or use different formats like "Smith, John" versus "John Smith." Some PIs also publish under different name variations or may have awards under a previous institutional affiliation.

Does this tool show all NIH-funded PIs?

The tool searches NIH RePORTER data for the keyword and year range you specify. It returns PIs whose funded projects match your search terms. PIs with grants in unrelated areas or whose projects use different terminology will not appear in keyword-filtered results.

What is the difference between "Likely hiring" and "Training-friendly" filters?

"Likely hiring" flags PIs with large new awards or activity codes typically associated with lab expansion. "Training-friendly" identifies awards that include training components or are at institutions known for postdoctoral programs. Both are heuristic filters to help prioritize your outreach.

How to use this well

Start broad, then narrow. Search a field first, then refine by timeframe once you understand who is currently active.

After you find a promising PI, cross-check them in Check PI Funding and review their institution, mechanism type, and project abstracts before reaching out.

What a match means

A result means the keyword appears relevant to the funded project data we searched. It does not guarantee the PI is hiring or that the grant is still active.

Use the abstract, award year, mechanism, and organization context to decide whether the record is strategically relevant.

Data limits

NIH records can lag, institutional names can vary, and some investigators publish or file awards under multiple name formats.

For details on source coverage and refresh cadence, read Data & Methodology.

Related guides

Companion guides for turning a PI search result into useful outreach or a job lead.

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How Postdocs Can Find PIs with New NIH Funding

A tactical job-search guide for identifying recently funded labs, judging fit, and timing outreach to principal investigators.

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How to Contact a PI: Finding Emails and Crafting the Perfect Message

Emailing strategies, outreach examples, and a workflow for turning NIH funding signals into focused PI conversations.

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How to Read a New NIH Award Like a Hiring Signal

A practical framework for using newly funded NIH awards to judge whether a lab may be expanding, hiring, or worth contacting now.

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Funding Strategy16 min read

How to Find NIH Funding Opportunities: A Step-by-Step Guide for Researchers

Learn how to find NIH funding opportunities using the NIH Guide, Grants.gov, FOAs, NIH RePORTER, and program officer outreach.

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Recently Funded Labs in Trending Areas

Principal investigators who received NIH awards in the last 90 days, organized by research area. Use this as a starting point for postdoc searches, collaborator outreach, or competitor scans. Counts and labs refresh daily.

Alzheimer's disease

Neurodegeneration, biomarkers, and disease-modifying therapies.

  • Carlos Cruchaga — WASHINGTON UNIVERSITY, MO
    CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"
    $101,153 · awarded Feb 25, 2026 · 3U01AG084514-01A1S1
  • Carlos Cruchaga — WASHINGTON UNIVERSITY, MO
    CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"
    $3,086,339 · awarded Feb 19, 2026 · 1U01AG084514-01A1
  • HARALD SONTHEIMER — UNIVERSITY OF VIRGINIA, VA
    Extracellular matrix and memory impairments in Alzheimer disease
    $709,066 · awarded Apr 7, 2026 · 5R01AG085359-03
  • Keith Josephs — MAYO CLINIC ROCHESTER, MN
    The neurobiology of two distinct subtypes of neurodegenerative apraxia of speech: phenotypes of Alzheimer disease related 4-repeat tauopathies
    $643,670 · awarded Apr 1, 2026 · 5R01DC014942-09
  • DMITRIY YABLONSKIY — WASHINGTON UNIVERSITY, MO
    Deep-Learning-Augmented Quantitative Gradient Recalled Echo (DLA-qGRE) MRI for in vivo Clinical Evaluation of Brain Microstructural Neurodegeneration in Alzheimer Disease
    $661,985 · awarded Mar 3, 2026 · 4R01AG082030-02
Search more PIs in Alzheimer's disease →

CRISPR & gene editing

Therapeutic gene editing, base editing, and prime editing.

  • Changchun Liu — UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT
    Asymmetric CRISPR Approach for Nucleic Acid Quantification
    $643,849 · awarded Mar 30, 2026 · 2R01EB023607-06A1
  • William Pu — BOSTON CHILDREN'S HOSPITAL, MA
    A modular system for murine CRISPR genome and epigenome editing
    $267,000 · awarded Mar 27, 2026 · 5R21OD037909-02
  • Naama Aviram — SLOAN-KETTERING INST CAN RESEARCH, NY
    Molecular mechanisms of memory formation and tolerance in CRISPR-Cas systems
    $249,000 · awarded Apr 2, 2026 · 5R00GM148720-04
  • Mats Ljungman — UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
    Precision targeting of bladder cancer using CRISPR
    $582,849 · awarded Feb 17, 2026 · 5R01CA285730-03
  • Shannon Miller — SCRIPPS RESEARCH INSTITUTE, THE, CA
    Development of potent and safe CRISPR tools for in vivo gene editing using directed evolution
    $230,000 · awarded May 5, 2026 · 5R21EB036298-03
Search more PIs in CRISPR & gene editing →

Cancer immunotherapy

Checkpoint inhibitors, CAR-T, TIL therapy, and beyond.

  • TERRY SHEPPARD — KEYSTONE SYMPOSIA, CO
    Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations
    $5,000 · awarded Mar 3, 2026 · 1R13CA310704-01
  • Veronika Fedirko — UNIVERSITY OF TX MD ANDERSON CAN CTR, TX
    Gut Microbiome and Cancer Immunotherapy Outcomes in Advanced Renal Cell Carcinoma
    $927,329 · awarded Mar 3, 2026 · 5R01CA255322-05
  • Yuwen Zhu — UNIVERSITY OF COLORADO DENVER, CO
    The GPR171 pathway in cancer immunotherapy
    $355,706 · awarded Apr 2, 2026 · 5R01CA279398-04
  • ANDREW WIEMER — UNIVERSITY OF CONNECTICUT STORRS, CT
    Synthesis and evaluation of BTN3A1 ligands for cancer immunotherapy
    $374,171 · awarded May 1, 2026 · 5R01CA266138-05
  • Wei Hu — YALE UNIVERSITY, CT
    Novel Treg inactivating approach for cancer immunotherapy via targeted protein degradation
    $482,312 · awarded Apr 6, 2026 · 1R01CA295942-01A1
Search more PIs in Cancer immunotherapy →

GLP-1 & metabolic disease

Diabetes, obesity, and weight-loss therapeutic mechanisms.

  • ZHIPING PANG — RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ
    Synaptic and circuit mechanisms of central GLP-1 signaling in energy balance
    $479,051 · awarded Apr 23, 2026 · 5R01DK131452-05
  • Madhusmita Misra — UNIVERSITY OF VIRGINIA, VA
    Bone metabolism in adolescents undergoing GLP-1 receptor agonist therapy
    $471,776 · awarded Apr 24, 2026 · 5R01HD118635-07
  • STEVEN SCHWENDEMAN — UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
    Remote Loading of Melanocortin and GLP-1 Peptides in Polymers for Treatment of Obesity
    $231,000 · awarded Apr 17, 2026 · 1R56DK141545-01A1
  • Jessica Barson — DREXEL UNIVERSITY, PA
    Suppression of ethanol dependence-induced maladaptive appetitive and consummatory behavior by the GLP-1 system
    $564,306 · awarded May 5, 2026 · 1R01AA031732-01A1
  • MICHAEL CAMILLERI — MAYO CLINIC ROCHESTER, MN
    A Randomized, placebo-controlled trial of the effects of Long-Acting GLP-1 or Dual Incretin (GLP-1 and GIP) Modulation on Gastrointestinal Functions and Relationship to Weight Loss
    $322,800 · awarded Apr 9, 2026 · 5R01DK142606-02
Search more PIs in GLP-1 & metabolic disease →

Long COVID

Post-acute sequelae and chronic infection-driven illness.

  • Alexei Tumanov — UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX
    Lymphotoxin-dependent control of long COVID
    $234,715 · awarded Feb 13, 2026 · 1R21AI185790-01A1
  • Amal Amer — OHIO STATE UNIVERSITY, OH
    Role of the Non-canonical Inflammasome in SARS-CoV-2-mediated Pathology and Coagulopathy
    $2,974,582 · awarded Apr 21, 2026 · 5P01AI175399-03
  • Alba Azola — JOHNS HOPKINS UNIVERSITY, MD
    Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 onset ME/CFS versus Pre-Pandemic ME/CFS Patients
    $633,378 · awarded Apr 17, 2026 · 1R01NS147100-01
  • DANIELLE REED — MONELL CHEMICAL SENSES CENTER, PA
    Inflammation and chemosensory loss
    $2,654,249 · awarded Feb 26, 2026 · 1P50DC022549-01A1
  • Jarred Younger — UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL
    Low-dose naltrexone (LDN) for the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
    $556,686 · awarded Mar 6, 2026 · 1UG3NS141843-01A1
Search more PIs in Long COVID →