Matthias Nahrendorf

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

High-opportunity lead · 88/100

Likely hiring

Large award

Very recent

Active award

$2,395,002

FY 2026

Project Title

Hematopoiesis in Cardiovascular Disease

Grant Number:

5P01HL142494-07

Activity Code:

P01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2018

End Date:

1/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Leukocytes are descendants of hematopoietic stem and progenitor cells (HSPC) and are made in the bone marrow. Innate immune cells defend us against pathogens but may also attack cardiovascular tissues, thereby producing inflamed atherosclerotic plaques, organ ischemia and failing myocardium. In the ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jennifer S Pollock

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 88/100

Likely hiring

Large award

Very recent

Active award

$2,193,510

FY 2026

Project Title

Early Life Stress Induced Mechanisms of Cardiovascular Disease Risk and Resilience

Grant Number:

5P01HL158500-04

Activity Code:

P01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

OVERALL SUMMARY Early life stress (ELS) is defined as stressful and traumatic events, such as household dysfunction, neglect, sexual or physical abuse, economic hardship, and exposure to violence, experienced up to 18 years. ELS was identified as a cardiovascular disease (CVD) risk factor over 20 ye...

Research Terms

<0-11 years old><12-20 years old><21+ years old><Address><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Animal Model><Animal Models and Related Studies><BP control><BP management><Basic Research><Basic Science><Bioinformatics><Biometrics><Biometry><Biostatistics><Blood Pressure><Blood Vessels><Blood monocyte><CNS Nervous System><Cardiac Chronotropism><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Central Nervous System><Child><Child Rearing><Child Youth><Children (0-21)><Clinic><Clinical><Collaborations><Data><Diastolic Pressure><Diastolic blood pressure><Diet><Dysfunction><Endothelium><Ensure><Europe><Exposure to><Financial Hardship><Functional disorder><Future><GI microbiome><Goals><Grant><Health><Heart Rate><Heart Vascular><History><Household><Human><Hypertension><Immune Cell Activation><Individual><Inflammation><Inflammation Mediators><Inflammatory><Intervention Strategies><Life><Life Stress><Macrophage><Manuscripts><Marrow monocyte><Measurement><Mediating><Mentors><Mission><Modern Man><Molecular><Mφ><NHLBI><National Heart, Lung, and Blood Institute><Neuraxis><North America><P01 Mechanism><P01 Program><PBMC><Parenting><Parenting behavior><Peripheral><Peripheral Blood Mononuclear Cell><Persons><Phenotype><Physical activity><Physiologic pulse><Physiopathology><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Program Project Grant><Program Research Project Grants><Psychologic Stress><Psychological Stress><Publications><Pulse><Recording of previous events><Reproducibility><Research Program Projects><Research Specimen><Risk><Risk Factors><Rodent><Rodent Model><Rodentia><Rodents Mammals><Sampling><Scientific Publication><Sexual abuse><Specimen><Stressful Event><Structure><System><Techniques><Technology><Telemetries><Telemetry><Temperature><Translating><Translations><Vascular Diseases><Vascular Disorder><Vascular Endothelium><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular resistance><Work><abuse neglect><adolescence (12-20)><adulthood><blood pressure control><blood pressure management><blood vessel disorder><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><childrearing><circadian><circulatory system><clinical relevance><clinically relevant><cost><data analysis core><data analysis research core><data analytics core><data analytics research core><data management><diets><digestive tract microbiome><disease risk><disorder risk><early adulthood><early life stress><economic hardship><economic strain><effective therapy><effective treatment><emerging adult><enteric microbiome><epigenome><experience><exposure to violence><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><gastrointestinal microbiome><global gene expression><global transcription profile><gut microbiome><gut-associated microbiome><health care burden><high blood pressure><histories><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><immune activation><inflammatory mediator><insight><intestinal biome><intestinal microbiome><juvenile><juvenile human><kids><later in life><later life><life-style factor><lifestyle factors><metabolome><metabonome><model of animal><monocyte><multiomics><multiple omics><neglect and abuse><neural network><novel><panomics><pathophysiology><physical abuse><physical maltreatment><programs><prospective><protective factors><resilience><resilient><sex abuse><sexually abused><stressful experience><stressful life event><stressful life experience><stressor><synergism><telemetric><transcriptome><translation><translational opportunities><translational potential><translational study><traumatic event><vascular><vascular dysfunction><vasculopathy><violence exposure><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JAY D. HORTON

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$2,484,600

FY 2026

Project Title

New Approaches to Reduce Residual Cardiovascular Risk

Grant Number:

5P01HL160487-05

Activity Code:

P01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

PPG Title: New Approaches to Reduce Residual Cardiovascular Risk SUMMARY/ABSTRACT In the last 40 years, significant progress has been made in reducing cardiovascular events by lowering plasma LDL-cholesterol (LDL-C). While statins and PCSK9 inhibitors effectively decrease LDL-C levels, significant r...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kiran Musunuru

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 80/100

Likely hiring

Large award

Very recent

Active award

$1,137,435

FY 2026

Project Title

Therapeutic editing for cardiovascular diseases

Grant Number:

1R35HL183558-01

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/20/2026

End Date:

1/31/2033

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY For the past decade, my independent laboratory has pioneered the use of gene-editing tools for therapeutic This work has culminated in clinical trials of PCSK9 and ANGPTL3 base editing, with PCSK9 representing the first base-editing therapeutic administered to patients anywhere in th...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Daniel James Rader

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 80/100

Likely hiring

Large award

Very recent

Active award

$1,077,264

FY 2026

Project Title

From genetic association to function: pleiotropic novel genes and variants linking lipid metabolism and cardiovascular diseases

Grant Number:

5R35HL172107-03

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Human genetic investigations have nominated hundreds of novel genomic loci harboring genes that influence a range of cardiovascular (CV) diseases and their risk factors, including plasma lipids. However, only a fraction of these novel loci have been investigated to determine the caus...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nicholas James Leeper

STANFORD UNIVERSITY, STANFORD, CA

High-opportunity lead · 80/100

Likely hiring

Large award

Very recent

Active award

$1,054,779

FY 2026

Project Title

The role of cancer in cardiovascular disease

Grant Number:

5R35HL176060-02

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2025

End Date:

1/31/2032

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Cancer and cardiovascular disease remain the world’s two leading killers. Historically considered distinct entities, emerging data have identified numerous shared risk factors, and demonstrated that cancer patients are at increased risk for cardiovascular events. However, ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amit Jasvant Shah

EMORY UNIVERSITY, ATLANTA, GA

High-opportunity lead · 80/100

Likely hiring

Large award

Very recent

Active award

$1,034,979

FY 2026

Project Title

Investigation of Sex Differences in Cardiovascular Risk in Rural Communities

Grant Number:

5R01HL163998-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Women living in the rural United States experienced a disproportionate increase in premature coronary heart disease (CHD) mortality between 2009 and 2017 compared to other demographic groups, which otherwise enjoyed a reduction in CHD events. Worsening mental health is a growing concern in rural are...

Research Terms

<21+ years old><Acceleration><Access to Care><Address><Adult><Adult Human><Affect><Age><Ankle><Appalachia><Appalachian><Appalachian Region><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Behavior><Behavioral><Biologic Factor><Biological Factors><Biological Markers><Blood Vessels><Brain><Brain Nervous System><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Toxicity><Cardiotoxic><Cardiotoxicity><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cell Phone><Cellular Phone><Cellular Telephone><Chest><Clinical><Clinical Treatment><Cohort Studies><Coronary Disease><Coronary heart disease><Cytokines and Inflammatory Response><Data><Delta Region of Mississippi><Differences between sexes><Differs between sexes><Disparities><Disparity><Domestic Violence><ECG><EKG><Ecological momentary assessment><Economics><Electrocardiogram><Electrocardiography><Encephalon><Endocrine><Evaluation><Event><Exposure to><Face><Family Violence><Financial Hardship><HPGF><Health Services Accessibility><Heart><Heart Diseases><Heart Vascular><Hepatocyte-Stimulating Factor><Hormonal><Hybridoma Growth Factor><Hyperlipemia><Hyperlipidemia><Hypertension><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Immune><Immunes><Incidence><Individual><Inflammation><Inflammatory><Inflammatory Response Pathway><Interleukin-6><Investigation><Life><MGI-2><Measures><Mental Depression><Mental Health><Mental Hygiene><Metabolic><Mississippi Delta><Mobile Phones><Monitor><Moods><Movement><Muellerian inhibiting hormone><Mullerian-inhibiting factor><Myeloid Differentiation-Inducing Protein><Neighborhoods><Neuroendocrine><Neuroendocrine System><Neurosecretory Systems><Ovarian><Ovarian aging><PTSD><Pathogenesis><Pathway interactions><Patient Self-Report><Pattern><Persons><Phenotype><Physical activity><Physiologic><Physiologic Monitoring><Physiologic pulse><Physiological><Physiological Monitoring><Plasmacytoma Growth Factor><Play><Policies><Population><Post-Traumatic Neuroses><Post-Traumatic Stress Disorders><Posttraumatic Neuroses><Psychologic Stress><Psychological Health><Psychological Stress><Psychosocial Assessment and Care><Psychosocial Stress><Public Health><Pulse><R-Series Research Projects><R01 Mechanism><R01 Program><Race><Races><Regio tarsalis><Reproductive Physiology><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Resources><Respiration><Risk><Risk Factors><Rural><Rural Community><Safety><Sampling><Self-Report><Sentinel><Sex Differences><Sexual differences><Sleep><Socioeconomic Factors><Stereotyping><Stress><Stressful Event><Substance abuse problem><Testing><Thorace><Thoracic><Thorax><Trauma><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><abuse of substances><access to health services><access to services><access to treatment><accessibility to health services><adulthood><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging human ovary><aging ovary><aging population><anti-mullerian factor><anti-mullerian hormone><availability of services><bio-markers><biologic marker><biological adaptation to stress><biological sex><biomarker><biopsychosocial><body movement><cardiac disease risk><cardiac disorder risk><cardiometabolic risk><cardiovascular function><cardiovascular risk><cardiovascular risk factor><care access><childbearing age><circadian><circulatory system><clinical intervention><clinical therapy><cohort><cohort research study><cohort survey><coronary artery calcium scoring><coronary calcium scoring><coronary disorder><depression><economic><economic hardship><economic strain><experience><faces><facial><fertile age><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><health service access><health services availability><heart disease risk><heart disorder><heart disorder risk><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><iPhone><improved><improved outcome><indexing><insight><interferon beta 2><male><men><mid life><mid-life><middle age><middle aged><midlife><mortality><mullerian inhibiting substance><mullerian regression factor><mullerian-inhibiting hormone><mullerian-inhibitory substance><multi-modality><multimodality><novel><ovarian senescence><ovulatory senescence><pathway><perceived stress><perception of stress><population aging><post-trauma stress disorder><posttrauma stress disorder><premature><prematurity><primary outcome><psychosocial><psychosocial assessment><psychosocial care><psychosocial studies><psychosocial support><racial><racial background><racial origin><reactioncrisis><reproductive><reproductive age><reproductive aging><reproductive cell senescence><reproductive senescence><reproductive years><respiratory mechanism><rural Americans><rural area><rural counties><rural location><rural region><secondary outcome><self-reported stress><sensor><service availability><sex><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><smart phone><smartphone><social><social adversity><social cohesion><socio-demographic groups><socio-economic><socio-economic factors><socio-economically><sociodemographic group><socioeconomically><socioeconomics><stress perception><stress response><stressreaction><stressful experience><stressful life event><stressful life experience><substance abuse><tool><traumatic neurosis><treatment access><trend><trial regimen><trial treatment><vascular><wearable><wearable device><wearable electronics><wearable system><wearable technology><wearable tool><wearables><wristband><young woman><younger age><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Viola Vaccarino

EMORY UNIVERSITY, ATLANTA, GA

High-opportunity lead · 80/100

Likely hiring

Large award

Very recent

Active award

$1,034,979

FY 2026

Project Title

Investigation of Sex Differences in Cardiovascular Risk in Rural Communities

Grant Number:

5R01HL163998-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Women living in the rural United States experienced a disproportionate increase in premature coronary heart disease (CHD) mortality between 2009 and 2017 compared to other demographic groups, which otherwise enjoyed a reduction in CHD events. Worsening mental health is a growing concern in rural are...

Research Terms

<21+ years old><Acceleration><Access to Care><Address><Adult><Adult Human><Affect><Age><Ankle><Appalachia><Appalachian><Appalachian Region><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Behavior><Behavioral><Biologic Factor><Biological Factors><Biological Markers><Blood Vessels><Brain><Brain Nervous System><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Toxicity><Cardiotoxic><Cardiotoxicity><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cell Phone><Cellular Phone><Cellular Telephone><Chest><Clinical><Clinical Treatment><Cohort Studies><Coronary Disease><Coronary heart disease><Cytokines and Inflammatory Response><Data><Delta Region of Mississippi><Differences between sexes><Differs between sexes><Disparities><Disparity><Domestic Violence><ECG><EKG><Ecological momentary assessment><Economics><Electrocardiogram><Electrocardiography><Encephalon><Endocrine><Evaluation><Event><Exposure to><Face><Family Violence><Financial Hardship><HPGF><Health Services Accessibility><Heart><Heart Diseases><Heart Vascular><Hepatocyte-Stimulating Factor><Hormonal><Hybridoma Growth Factor><Hyperlipemia><Hyperlipidemia><Hypertension><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Immune><Immunes><Incidence><Individual><Inflammation><Inflammatory><Inflammatory Response Pathway><Interleukin-6><Investigation><Life><MGI-2><Measures><Mental Depression><Mental Health><Mental Hygiene><Metabolic><Mississippi Delta><Mobile Phones><Monitor><Moods><Movement><Muellerian inhibiting hormone><Mullerian-inhibiting factor><Myeloid Differentiation-Inducing Protein><Neighborhoods><Neuroendocrine><Neuroendocrine System><Neurosecretory Systems><Ovarian><Ovarian aging><PTSD><Pathogenesis><Pathway interactions><Patient Self-Report><Pattern><Persons><Phenotype><Physical activity><Physiologic><Physiologic Monitoring><Physiologic pulse><Physiological><Physiological Monitoring><Plasmacytoma Growth Factor><Play><Policies><Population><Post-Traumatic Neuroses><Post-Traumatic Stress Disorders><Posttraumatic Neuroses><Psychologic Stress><Psychological Health><Psychological Stress><Psychosocial Assessment and Care><Psychosocial Stress><Public Health><Pulse><R-Series Research Projects><R01 Mechanism><R01 Program><Race><Races><Regio tarsalis><Reproductive Physiology><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Resources><Respiration><Risk><Risk Factors><Rural><Rural Community><Safety><Sampling><Self-Report><Sentinel><Sex Differences><Sexual differences><Sleep><Socioeconomic Factors><Stereotyping><Stress><Stressful Event><Substance abuse problem><Testing><Thorace><Thoracic><Thorax><Trauma><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><abuse of substances><access to health services><access to services><access to treatment><accessibility to health services><adulthood><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging human ovary><aging ovary><aging population><anti-mullerian factor><anti-mullerian hormone><availability of services><bio-markers><biologic marker><biological adaptation to stress><biological sex><biomarker><biopsychosocial><body movement><cardiac disease risk><cardiac disorder risk><cardiometabolic risk><cardiovascular function><cardiovascular risk><cardiovascular risk factor><care access><childbearing age><circadian><circulatory system><clinical intervention><clinical therapy><cohort><cohort research study><cohort survey><coronary artery calcium scoring><coronary calcium scoring><coronary disorder><depression><economic><economic hardship><economic strain><experience><faces><facial><fertile age><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><health service access><health services availability><heart disease risk><heart disorder><heart disorder risk><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><iPhone><improved><improved outcome><indexing><insight><interferon beta 2><male><men><mid life><mid-life><middle age><middle aged><midlife><mortality><mullerian inhibiting substance><mullerian regression factor><mullerian-inhibiting hormone><mullerian-inhibitory substance><multi-modality><multimodality><novel><ovarian senescence><ovulatory senescence><pathway><perceived stress><perception of stress><population aging><post-trauma stress disorder><posttrauma stress disorder><premature><prematurity><primary outcome><psychosocial><psychosocial assessment><psychosocial care><psychosocial studies><psychosocial support><racial><racial background><racial origin><reactioncrisis><reproductive><reproductive age><reproductive aging><reproductive cell senescence><reproductive senescence><reproductive years><respiratory mechanism><rural Americans><rural area><rural counties><rural location><rural region><secondary outcome><self-reported stress><sensor><service availability><sex><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><smart phone><smartphone><social><social adversity><social cohesion><socio-demographic groups><socio-economic><socio-economic factors><socio-economically><sociodemographic group><socioeconomically><socioeconomics><stress perception><stress response><stressreaction><stressful experience><stressful life event><stressful life experience><substance abuse><tool><traumatic neurosis><treatment access><trend><trial regimen><trial treatment><vascular><wearable><wearable device><wearable electronics><wearable system><wearable technology><wearable tool><wearables><wristband><young woman><younger age><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Douglas E Vaughan

NORTHWESTERN UNIVERSITY AT CHICAGO, CHICAGO, IL

High-opportunity lead · 80/100

Likely hiring

Large award

Very recent

Active award

$1,027,909

FY 2026

Project Title

Heterozygous SERPINE1 Deficiency Confers Durable Cardiovascular Fitness in Humans

Grant Number:

5R35HL171553-03

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY. The number of Americans over age 65 years is growing and is projected to increase from approximately 39 million in 2010 to an estimated 71 million in 2030. The prevalence of multi-morbidity, including cardiovascular disease, Alzheimer's dementia, emphysema, and diabetes increases significan...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD dementia><Age><Aged 65 and Over><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><American><Amish><Back><Biological Aging><Blood Vessels><Body System><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Pathology><Cardiovascular system><Cell Body><Cells><Communities><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Development><Diabetes Mellitus><Diathesis><Disease susceptibility><Dorsum><EC 3.4.21.7><Emphysema><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Fasting><Gene Proteins><Generations><Geography><Heart><Heart Vascular><Heterozygote><Human><Humulin R><Insulin><Kidney><Kidney Urinary System><Laboratories><Link><Mice><Mice Mammals><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><Murine><Mus><Natural experiment><Novolin R><Obesity><Obstructive Lung Diseases><Organ System><Pathology><Plasminogen><Population><Prevalence><Primary Senile Degenerative Dementia><Privatization><Profibrinolysin><Protein Gene Products><Proteins><Pulmonary Emphysema><Regular Insulin><Risk Factors><Role><SERPINE1><SERPINE1 gene><Skin><Testing><Therapeutic><Therapeutic Intervention><Translating><Variant><Variation><above age 65><adiposity><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age associated effects><age effect><age of 65 years onward><age related effects><aged 65 and greater><aged 65+><aged ≥65><ages><aging associated><aging effect><aging prevention><aging related><anti aging><anti geronic><antiaging><atherosclerotic coronary disease><biological process of age><cardiovascular disorder><cardiovascular fitness><circulatory system><coronary arterial disease><corpulence><design><designing><developmental><diabetes><emphysematous><epigenetically><experiment><experimental research><experimental study><experiments><fasted><fasts><fatty liver disease><flexibility><flexible><gene null><heterozygosity><human old age (65+)><iPS><iPSC><iPSCs><impact of age><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><influence of age><intervention therapy><kindred><liability to disease><life span><life style intervention><lifespan><lifestyle intervention><loss of function><loss of function mutation><molecular profile><molecular signature><multidisciplinary><multimorbidity><multiple chronic conditions><null mutation><obstructive pulmonary diseases><over 65 years><pharmacologic><pleiotropic effect><pleiotropism><pleiotropy><preservation><prevent><prevent age related><prevent aging><preventing><primary degenerative dementia><protective effect><renal><reparative ability><reparative capacity><reparative potential><resilience><resilient><senescence><senescent><senile dementia of the Alzheimer type><social role><suppress aging><telomere><vascular><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eric D Lazartigues

LSU HEALTH SCIENCES CENTER, NEW ORLEANS, LA

High-opportunity lead · 80/100

Likely hiring

Large award

Very recent

Active award

$1,008,719

FY 2026

Project Title

Screening and validation of miRNA targets for neurogenic hypertension.

Grant Number:

1R35HL184169-01

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/6/2026

End Date:

3/31/2033

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Program Summary With prevalence as high as 55% in individuals aged 55 and older in the United States, hypertension (HTN) is a major risk factor contributing to cardiovascular diseases and global mortality, hence remaining an increasingly important medical and public health issue. Despite the abundan...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Changcheng Zhou

UNIVERSITY OF CALIFORNIA RIVERSIDE, RIVERSIDE, CA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$838,201

FY 2026

Project Title

Role of PXR in EDC-induced cardiovascular disease

Grant Number:

5R35ES035015-04

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/5/2023

End Date:

3/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Atherosclerotic cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide and recent large-scale human studies have implicated a link between exposure to endocrine disrupting chemicals (EDCs) and CVD. However, how exposure to EDCs and other environmental ...

Research Terms

<21+ years old><ASCVD><Adult><Adult Human><Affect><Agonist><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Autoregulation><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Causality><Cause of Death><Cell Body><Cells><Ceramides><Chemical Exposure><Chemicals><Chronic><Citrates><Code><Coding System><DNA Molecular Biology><Development><Dimensions><Disease><Disorder><Domestic Horse><Dyslipidemias><Endocrine Disrupter><Endocrine Disrupting Chemicals><Endocrine Disruptors><Endocrine disrupting agent><Environment><Environmental Health><Environmental Health Science><Equine><Equine Species><Equus caballus><Equus przewalskii><Etiology><Exposure to><Funding><Genes><Health><Heart Vascular><Homeostasis><Horses><Human><Individual><Laboratories><Ligands><Link><Lipids><Longitudinal Studies><Longitudinal Surveys><Mediating><Microplastics><Modern Man><Molecular Biology><Morbidity><NIEHS><National Institute of Environmental Health Sciences><Non-Polyadenylated RNA><PXR receptor><Paternal Exposure><Pharmacology><Physiological Homeostasis><Position><Positioning Attribute><RNA><RNA Gene Products><Receptor Signaling><Regulation><Research><Ribonucleic Acid><Risk Assessment><Role><Sperm><Spermatozoa><Toxicology><Training><Xenobiotics><adulthood><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><bisphenol A><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><causation><chemical association><circulatory system><consumer product><developmental><diphenylolpropane><disease causation><endocrine disrupting compound><environmental chemical><experience><health assessment><human disease><innovate><innovation><innovative><interest><intergenerational><long-term study><longitudinal outcome studies><longitudinal research study><mortality><mouse model><murine model><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><offspring><phthalates><pregnane X receptor><programs><sensor><social role><sperm cell><tool><zoosperm>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Steven D Crowley

DUKE UNIVERSITY, DURHAM, NC

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$821,618

FY 2026

Project Title

Epithelial actions of a ubiquitin editor restrict immune-regulated sodium transport in hypertension

Grant Number:

1R01DK142722-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/17/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Hypertension impacts up to 40% of adults worldwide with disproportionate effects in low-income countries. Uncontrolled hypertension is a leading driver of cardiovascular and chronic kidney disease (CKD). Blood pressure remains uncontrolled in up to half of hypertensive patients, highlighting the nee...

Research Terms

<21+ years old><APF-1><ATP-Dependent Proteolysis Factor 1><Adult><Adult Human><Apoplexy><Attenuated><Autoimmune Diseases><BP reduction><Blood Pressure><Blood leukocyte><Body Tissues><Brain Vascular Accident><Cardiac Failure Congestive><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell surface><Cells><Cellular injury><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Co-culture><Cocultivation><Coculture><Coculture Techniques><Congestive Heart Failure><Data><ESKD><ESRD><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Epithelium><Event><Excretory function><Generations><Genes><HMG-20><Health Benefit><Heart Decompensation><Heart Vascular><Henle's loop><High Mobility Protein 20><Human><Hypertension><Immune><Immune response><Immunes><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Impairment><In Vitro><Inflammation Mediators><Inflammatory><Intracellular Communication and Signaling><Isoforms><Kidney><Kidney Diseases><Kidney Tubules><Kidney Urinary System><Leukocytes><Leukocytes Reticuloendothelial System><LoxP-flanked allele><Marrow leukocyte><Measures><Mediating><Mediator><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Na element><Nephrons><Nephropathy><Organ><Pathway interactions><Patients><Phosphorylation><Predisposition><Protein Cleavage><Protein Isoforms><Protein Phosphorylation><Proteolysis><Proximal Kidney Tubules><Renal Disease><Renal tubule structure><Risk><Role><Signal Transduction><Signal Transduction Systems><Signaling><Sodium><Sodium Chloride><Sorting><Stroke><Susceptibility><T-Cell Activation><T-Cells><T-Lymphocyte><Testing><Tissues><Tubular><Tubular formation><Ubiquitilation><Ubiquitin><Ubiquitination><Ubiquitinoylation><Uriniferous Tube><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><White Blood Cells><White Cell><Wild Type Mouse><absorption><activate T cells><adulthood><apical membrane><attenuate><attenuates><autoimmune condition><autoimmune disorder><autoimmunity disease><biological signal transduction><blood pressure elevation><blood pressure reduction><brain attack><cardiovascular disorder><cell damage><cell injury><cellular damage><cerebral vascular accident><cerebrovascular accident><chronic heart failure><chronic kidney disease><circulatory system><cohort><cytokine><damage to cells><damage to kidney><elevated blood pressure><excretion><floxed><floxed allele><health and care delivery><health care delivery><health delivery systems><health services delivery><high blood pressure><host response><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive response><increase in blood pressure><increased blood pressure><infection risk><inflammatory mediator><inhibitor><injury to cells><kidney damage><kidney disorder><low income country><lower BP><lower blood pressure><lowers blood pressure><mouse model><murine model><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><overexpress><overexpression><pathway><pre-clinical><preclinical><reduce BP><reduce blood pressure><reduction in BP><reduction in blood pressure><renal><renal damage><renal disorder><renal proximal tubule><renal tubule><response><salt><social role><solute><stroked><strokes><success><systemic inflammation><systemic inflammatory response><thymus derived lymphocyte><ubiquination><ubiquitin conjugation><white blood cell><white blood corpuscle><wildtype mouse>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

L Elliot Elliot Hong

UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$764,880

FY 2026

Project Title

The Vascular Axis in Schizophrenia Brain-Body Aging

Grant Number:

5R01MH133812-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/8/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary People with schizophrenia spectrum disorders have a shorter lifespan and higher morbidity and mortality than the general population, with cardiovascular conditions on top of the leading causes. Brain imaging research has revealed accelerated age-related brain changes in patients with...

Research Terms

<3-D><3-Dimensional><3D><Acceleration><Access to Care><Age><Aging><Antipsychotic Agents><Antipsychotic Drugs><Antipsychotics><Apoplexy><Arteries><Astrocytes><Astrocytus><Astroglia><Autopsy><Autoregulation><Biological Markers><Biology><Blood - brain barrier anatomy><Blood Vessel Imaging><Blood Vessels><Blood brain barrier dysfunction><Blood-Brain Barrier><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain Trauma><Brain Vascular><Brain Vascular Accident><Brain imaging><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Cell Body><Cells><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cerebrovascular system><Cerebrum><Data><Diffusion><Disease><Disorder><Dysfunction><Early Intervention><Encephalon><Encephalon Diseases><Endothelial Cells><Endothelium><Functional disorder><General Population><General Public><Goals><Guide prevention><Health><Health Services Accessibility><Heart Vascular><Hemato-Encephalic Barrier><Homeostasis><Hydrogen Oxide><Imaging Procedures><Imaging Technics><Imaging Techniques><Impairment><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigation><Life><Long-term cohort><Longitudinal cohort><Major Tranquilizers><Major Tranquilizing Agents><Measures><Mediating><Mediation><Medical><Metabolic syndrome><Methods><Modeling><Morbidity><Negotiating><Negotiation><Neuroleptic Agents><Neuroleptic Drugs><Neuroleptics><Outcome><Pathway interactions><Patients><Peripheral><Persons><Physiologic pulse><Physiological Homeostasis><Physiopathology><Premature Mortality><Preventative intervention><Prevention><Pulse><Reporting><Research><Risk Factors><Schizophrenia><Schizophrenic Disorders><Smoking><Stress><Stroke><System><Techniques><Testing><Time><Traumatic Brain Injury><Water><White Matter Disease><accelerated aging><accelerated biological age><accelerated biological aging><access to health services><access to services><access to treatment><accessibility to health services><adult youth><age acceleration><age associated><age associated alterations><age associated changes><age associated effects><age correlated><age correlated alterations><age correlated changes><age dependent><age dependent alterations><age dependent changes><age effect><age group><age induced alterations><age induced changes><age linked><age related><age related alterations><age related changes><age related effects><age specific><age specific alterations><age specific changes><aged brain><ages><aging associated><aging associated alterations><aging associated changes><aging associated disease><aging associated disorders><aging brain><aging correlated alterations><aging correlated changes><aging dependent alterations><aging dependent changes><aging effect><aging induced alterations><aging induced changes><aging related><aging related alterations><aging related changes><aging related disease><aging related disorders><aging specific alterations><aging specific changes><allostatic load><alterations with age><arterial spin labeling><arterial spin tagging><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><astrocytic glia><availability of services><bio-markers><biologic marker><biomarker><blood vessels in the brain><bloodbrain barrier><brain attack><brain blood vessels><brain vasculature><brain visualization><burden of disease><burden of illness><cardiovascular disorder><care access><cerebral><cerebral blood vessel><cerebral vascular><cerebral vascular accident><cerebral vasculature><cerebro-vascular><cerebrovascular><cerebrovascular accident><cerebrovascular vessels><cerebrovasculature><changes with age><circulatory system><co-morbid><co-morbidity><comorbidity><dementia praecox><diffused><diffuses><diffusing><diffusions><disease associated with aging><disease burden><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><early onset><endothelial dysfunction><gray matter><health service access><health services availability><impact of age><influence of age><insight><intervention for prevention><life span><lifespan><longitudinal design><longitudinal experimental design><longitudinal research design><longitudinal study design><mortality><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><novel><older adult><older adulthood><pathophysiology><pathway><postmortem><premature><prematurity><prevention intervention><preventional intervention strategy><preventive intervention><reactive hyperemia><schizophrenia spectrum><schizophrenia spectrum disorder><schizophrenic><screening><screenings><service availability><sex><stroked><strokes><substantia alba><substantia grisea><three dimensional><traumatic brain damage><treatment access><vascular><vascular contributions><vascular imaging><vasculature Imaging><white matter><white matter change><young adult><young adult age><young adulthood>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Safiya Richardson

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$746,347

FY 2026

Project Title

EHR Nudges: Optimizing a Clinical Decision Support System for Evidence-Based Statin Medication Prescribing to Reduce the Risk of Cardiovascular Disease

Grant Number:

5R01HL171292-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT ABSTRACT Statins reduce the risk of major adverse cardiovascular events and mortality. However, providers fail to prescribe statin therapy for about half of patients meeting guideline criteria for initiation. The electronic health record (EHR) creates opportunities to develop clinical decisi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KATHRYN J MOORE

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$742,785

FY 2026

Project Title

The role of immune-responsive gene 1 and itaconate in atherosclerotic disease

Grant Number:

5R01HL172365-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY In atherosclerotic cardiovascular disease (ASCVD), chronic inflammation is a major risk factor that remains unaddressed by currently approved therapies. Existing therapies aimed at curbing ASCVD target lipid metabolic pathways, and many patients continue to be at high risk of cardiovascular ...

Research Terms

<1-Propene-1,2,3-tricarboxylic acid><3-D><3-Dimensional><3D><ASCVD><ATAC sequencing><ATAC-seq><ATACseq><Acceleration><Achilleic Acid><Aconitate><Aconitic Acid><Acontic Acid><Active Oxygen><Address><Adonic Acid><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Antiinflammatory Effect><Antioxidants><Apoplexy><Arterial Fatty Streak><Arterial Intimas><Arteries><Assay for Transposase-Accessible Chromatin using sequencing><Atherogenicity><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerosis-prone><Atherosclerosis-susceptible><Atherosclerotic Cardiovascular Disease><Automobile Driving><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Bacterial Infections><Basal Transcription Factor><Basal transcription factor genes><Beta Proprotein Interleukin 1><Blood Neutrophil><Blood Plasma><Blood Polymorphonuclear Neutrophil><Blood Vessels><Blood monocyte><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><Brain Vascular Accident><Carboxy-Lyases><Carboxyglutaconic Acid><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Carotid Artery Plaques><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular Stress><Cellular Stress Response><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><ChIP Sequencing><ChIP-seq><ChIPseq><Chemotactic Cytokines><Cholesterol><Chronic><Citric Acid Cycle><Citridic Acid><Citridinic Acid><Clinical><Coupled><Cytometry><Data><Decarboxylases><Deposit><Deposition><Disease Progression><Enzyme Gene><Enzymes><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Equisetic Acid><Event><Foundations><Fumarate Reductase><General Transcription Factor Gene><General Transcription Factors><Genes><Glycolysis><Glycolysis Inhibition><Goals><HPGF><Heart Vascular><Hepatocyte-Stimulating Factor><Homologous Chemotactic Cytokines><Human><Hybridoma Growth Factor><Hypercholesteremia><IFN-beta 2><IFNB2><IL-1 beta><IL-1 β><IL-1-b><IL-1β><IL-6><IL1-Beta><IL1-β><IL1B Protein><IL1F2><IL1β><IL6 Protein><Image><Immune><Immune response><Immunes><Immunity><Immunomodulation><Impairment><In Vitro><Infection><Inflammasome><Inflammation><Inflammatory><Inflammatory Response><Intercrines><Interleukin 1beta><Interleukin-1 beta><Interleukin-1β><Interleukin-6><Intermediary Metabolism><Intracellular Communication and Signaling><Investigation><Krebs Cycle><LDL><LDL Cholesterol><LDL Cholesterol Lipoproteins><LDL Lipoproteins><Learning><Lipids><Low Density Lipoprotein Cholesterol><Low-Density Lipoproteins><MGI-2><Macrophage><Marrow Neutrophil><Marrow monocyte><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Metabolic><Metabolic Control><Metabolic Pathway><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modern Man><Modification><Murine><Mus><Myeloid Cells><Myeloid Differentiation-Inducing Protein><Myeloid Progenitor><Myeloid Progenitor Cells><Myeloid Stem Cells><Myocardial Infarct><Myocardial Infarction><Mφ><Neutrophilic Granulocyte><Neutrophilic Leukocyte><O element><O2 element><Oxidative Stress><Oxygen><Oxygen Radicals><PBMC><Pathological Constriction><Pathway interactions><Patients><Peripheral Blood Mononuclear Cell><Permeability><Plaque Instability><Plasma><Plasma Serum><Plasmacytoma Growth Factor><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Pre-Clinical Model><Preclinical Models><Preinterleukin 1 Beta><Pro-Oxidants><Process><Production><Prone to atherosclerosis><Pyrocitric Acid><Reactive Oxygen Species><Regulation><Residual><Residual state><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Role><SIS cytokines><Signal Transduction><Signal Transduction Systems><Signaling><Stenosis><Sterility><Stroke><Subcellular Process><Succinate Dehydrogenase><Succinic Dehydrogenase><Succinic Oxidase><T-Cells><T-Lymphocyte><TCA cycle><Testing><Therapeutic><Therapeutic Uses><Time><Tissues><Training><Transcription Factor Proto-Oncogene><Transcription factor genes><Tricarboxylic Acid Cycle><United States><Work><anti-inflammatory effect><anti-microbial><antimicrobial><assay for transposase accessible chromatin followed by sequencing><assay for transposase accessible chromatin seq><assay for transposase accessible chromatin sequencing><assay for transposase-accessible chromatin with sequencing><atherogenesis><atheromatosis><atheroprone><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic vascular disease><bacteria infection><bacterial disease><beta-Lipoprotein Cholesterol><beta-Lipoproteins><biological signal transduction><brain attack><cardiac infarct><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><carotid plaque><cell stress><cerebral vascular accident><cerebrovascular accident><chemoattractant cytokine><chemokine><chromatin immunoprecipitation coupled with sequencing><chromatin immunoprecipitation followed by sequencing><chromatin immunoprecipitation with sequencing><chromatin immunoprecipitation-seq><chromatin immunoprecipitation-sequencing><circulatory system><coronary attack><coronary infarct><coronary infarction><cytokine><design><designing><driving><epigenetic gene silencing><epigenetic silencing><epigenetically><epigenomics><extracellular><feeding><fumarate hydrogenase><heart attack><heart infarct><heart infarction><high blood cholesterol><high dimensionality><high risk><host response><human RNA sequencing><human RNA-seq><hypercholesterolemia><imaging><immune modulation><immune regulation><immune system response><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><in vivo><in vivo Model><innovate><innovation><innovative><interferon beta 2><metabolic phenotype><metabolism measurement><metabolomics><metabonomics><metabotype><microbial><monocyte><mouse model><multiplexed imaging><murine model><myeloid precursor><myeloid stem and progenitor cell><neutrophil><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><ox-LDL><oxidized LDL><oxidized low density lipoprotein><pathway><plaque vulnerability><plaques in atherosclerosis><prevent><preventing><recruit><resolutions><response><scRNA sequencing><scRNA-seq><sensor><single cell RNA-seq><single cell RNAseq><single cell analysis><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><stem><sterile><stroked><strokes><susceptibility to atherosclerosis><systemic inflammation><systemic inflammatory response><three dimensional><thymus derived lymphocyte><transcription factor><treatment strategy><unstable plaque><vascular><western diet><western-style diet><western-type diet>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JULIO ALONSO CHIRINOS MEDINA

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$737,758

FY 2026

Project Title

Cardiovascular Risk, Vascular and Kidney Damage in COVID-19 Survivors

Grant Number:

5R01HL157108-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/20/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The coronavirus disease 2019 (COVID-19) pandemic is a public health crisis, characterized by pneumonia and multiorgan dysfunction. We previously demonstrated that community-acquired pneumonia increases the long- term risk of cardiovascular disease. There is an urgent need to investig...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jordana B. Cohen

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$737,758

FY 2026

Project Title

Cardiovascular Risk, Vascular and Kidney Damage in COVID-19 Survivors

Grant Number:

5R01HL157108-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/20/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The coronavirus disease 2019 (COVID-19) pandemic is a public health crisis, characterized by pneumonia and multiorgan dysfunction. We previously demonstrated that community-acquired pneumonia increases the long- term risk of cardiovascular disease. There is an urgent need to investig...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Fritz J Sedlazeck

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$719,909

FY 2026

Project Title

A novel graph approach to resolve challenging and medically relevant regions in the human genome

Grant Number:

1R01HG014006-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/13/2026

End Date:

2/28/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Despite improved human genome references, like the T2T and Human Pangenome References, limitations of short-read sequencing and inadequate tools preclude routine characterization of medically relevant complex regions like LPA, HLA, and GBA. This includes ‘graph genome’ methods, which have n...

Research Terms

<21+ years old><Address><Adult><Adult Human><Affect><Alleles><Allelomorphs><American><Benchmarking><Best Practice Analysis><Biochemical><Blood><Blood Reticuloendothelial System><Brittle Diabetes Mellitus><Cardiovascular Diseases><Catalogs><Clinical><Clinical genetics><Collection><Complex><Coupled><DNA mutation><DNA seq><DNA sequencing><DNAseq><Data><Development><Diagnostic><Disease><Disorder><European><Future><Gene variant><Genes><Genetic><Genetic Change><Genetic Diseases><Genetic Risk><Genetic defect><Genetic mutation><Genome><Genomic Segment><Genomics><Graph><Haplotypes><Health><Human Genome><IDDM><Individual><Insulin-Dependent Diabetes Mellitus><Intuition><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Kringle Domains><Kringles><Laboratories><Lipoprotein (a)><Lipoprotein Lp(a)><Lp(a)><Measurement><Medical><Medical Genetics><Methods><Mutation><Mutation Detection><NIH><National Institutes of Health><Orphan Disease><Paralysis Agitans><Parkinson><Parkinson Disease><Pathogenicity><Phenotype><Policies><Population><Primary Parkinsonism><Proteins><Protocol><Protocols documentation><Rare Diseases><Rare Disorder><Reporting><Research><Research Personnel><Researchers><Risk Assessment><Role><Software Framework><Structure><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><TOPMed><Testing><Trans-Omics for Precision Medicine><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States National Institutes of Health><Variant><Variation><Work><X Chromosome><adulthood><allelic variant><benchmark><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><catalog><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><clinical relevance><clinically relevant><cohort><computerized data processing><data processing><developmental><diagnostic tool><disease risk><disorder risk><entire genome><full genome><genetic condition><genetic disorder><genetic variant><genome mutation><genome segment><genomic data><genomic dataset><genomic region><genomic variant><human pangenome><human reference assembly><human reference genome><human whole genome><improved><insight><insulin dependent diabetes><insulin dependent type 1><intuitive><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><large data sets><large datasets><medical college><medical schools><new diagnostics><next generation diagnostics><novel><novel diagnostics><open data><open science><open source><open-source data><orphan disorder><pan-human genome><programs><school of medicine><social role><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><tool><type I diabetes><type one diabetes><user-friendly><variant detection><whole genome>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Girish Nitin Nadkarni

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$718,857

FY 2026

Project Title

Application of Machine Learning to Identify Obstructive Sleep Apnea Subgroups at Risk for Atherosclerosis Progression and Cardiovascular Disease Events (OSA-GRANDE)

Grant Number:

5R01HL168897-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Obstructive sleep apnea (OSA) affects over one billion adults and is an independent risk factor for cardiovascular disease (CVD). Yet, in randomized clinical trials (RCT), treatment of OSA has failed to demonstrate a beneficial impact of continuous positive airway pressure (CPAP) on ...

Research Terms

<21+ years old><Active Follow-up><Address><Adherence><Adult><Adult Human><Affect><Age><Area><Atrial Fibrillation><Auricular Fibrillation><Big Data><BigData><CPAP><CPAP Ventilation><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Characteristics><Classification><Clinical><Collaborations><Continuous Positive Airway Pressure><Data><Data Bases><Data Set><Databases><Drowsiness><Dyslipidemias><Effectiveness><Electronic Health Record><Ensure><Environment><Event><Goals><Health Care Costs><Health Costs><Health system><Heart Vascular><Heart failure><Heterogeneity><Individual><Intervention><Machine Learning><Medicine><Modeling><Multimodal ML><Multimodal machine learning><NIH><National Institutes of Health><Obstructive Sleep Apnea><Outcome><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Personalized medical approach><Physicians><Polysomnography><Population><Prediction of Response to Therapy><Publications><Research><Risk><Risk Assessment><Risk Reduction><Sample Size><Sampling><Scientific Publication><Severities><Sleep><Sleep Disorders><Sleep Monitoring><Somnography><Somnolence><Subgroup><Syndrome, Sleep Apnea, Obstructive><Systematics><Techniques><Time><Translations><United States National Institutes of Health><Work><active followup><acute coronary syndrome><adulthood><ages><atherosclerosis risk><atherosclerotic risk><cardiac failure><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><care as usual><circulatory system><clinical decision-making><clinical practice><clinical relevance><clinical validation><clinically relevant><cohort><computer based prediction><coronary artery calcium scoring><coronary calcium scoring><data base><data collected in real world><data-driven model><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><ethnic diversity><ethnically diverse><experience><follow up><follow-up><followed up><followup><hazard><high risk><improved><individualized approach><individualized predictions><machine based learning><machine learning based method><machine learning method><machine learning methodologies><multi-modal data><multi-modal datasets><multidisciplinary><multimodal data><multimodal datasets><multimodal learning><new approaches><novel approaches><novel strategies><novel strategy><patient oriented outcomes><patient population><personalization of treatment><personalized approach><personalized medicine><personalized predictions><personalized therapy><personalized treatment><precision approach><precision medicine><precision-based medicine><predict therapeutic response><predict therapy response><predictive modeling><predictive tools><randomized, clinical trials><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><respiratory><risk prediction system><risk prediction tool><risk stratification><risk-reducing><sleep amount><sleep diseases><sleep duration><sleep dysfunction><sleep episode><sleep illness><sleep interval><sleep length><sleep measurement><sleep period><sleep polysomnography><sleep problem><sleep quantity><sleep time><sleepiness><stratify risk><tailored approach><therapy optimization><therapy prediction><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><tool><translation><treatment as usual><treatment effect><treatment optimization><treatment planning><treatment prediction><treatment response prediction><usual care>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mayte Suarez-Farinas

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$718,857

FY 2026

Project Title

Application of Machine Learning to Identify Obstructive Sleep Apnea Subgroups at Risk for Atherosclerosis Progression and Cardiovascular Disease Events (OSA-GRANDE)

Grant Number:

5R01HL168897-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Obstructive sleep apnea (OSA) affects over one billion adults and is an independent risk factor for cardiovascular disease (CVD). Yet, in randomized clinical trials (RCT), treatment of OSA has failed to demonstrate a beneficial impact of continuous positive airway pressure (CPAP) on ...

Research Terms

<21+ years old><Active Follow-up><Address><Adherence><Adult><Adult Human><Affect><Age><Area><Atrial Fibrillation><Auricular Fibrillation><Big Data><BigData><CPAP><CPAP Ventilation><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Characteristics><Classification><Clinical><Collaborations><Continuous Positive Airway Pressure><Data><Data Bases><Data Set><Databases><Drowsiness><Dyslipidemias><Effectiveness><Electronic Health Record><Ensure><Environment><Event><Goals><Health Care Costs><Health Costs><Health system><Heart Vascular><Heart failure><Heterogeneity><Individual><Intervention><Machine Learning><Medicine><Modeling><Multimodal ML><Multimodal machine learning><NIH><National Institutes of Health><Obstructive Sleep Apnea><Outcome><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Personalized medical approach><Physicians><Polysomnography><Population><Prediction of Response to Therapy><Publications><Research><Risk><Risk Assessment><Risk Reduction><Sample Size><Sampling><Scientific Publication><Severities><Sleep><Sleep Disorders><Sleep Monitoring><Somnography><Somnolence><Subgroup><Syndrome, Sleep Apnea, Obstructive><Systematics><Techniques><Time><Translations><United States National Institutes of Health><Work><active followup><acute coronary syndrome><adulthood><ages><atherosclerosis risk><atherosclerotic risk><cardiac failure><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><care as usual><circulatory system><clinical decision-making><clinical practice><clinical relevance><clinical validation><clinically relevant><cohort><computer based prediction><coronary artery calcium scoring><coronary calcium scoring><data base><data collected in real world><data-driven model><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><ethnic diversity><ethnically diverse><experience><follow up><follow-up><followed up><followup><hazard><high risk><improved><individualized approach><individualized predictions><machine based learning><machine learning based method><machine learning method><machine learning methodologies><multi-modal data><multi-modal datasets><multidisciplinary><multimodal data><multimodal datasets><multimodal learning><new approaches><novel approaches><novel strategies><novel strategy><patient oriented outcomes><patient population><personalization of treatment><personalized approach><personalized medicine><personalized predictions><personalized therapy><personalized treatment><precision approach><precision medicine><precision-based medicine><predict therapeutic response><predict therapy response><predictive modeling><predictive tools><randomized, clinical trials><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><respiratory><risk prediction system><risk prediction tool><risk stratification><risk-reducing><sleep amount><sleep diseases><sleep duration><sleep dysfunction><sleep episode><sleep illness><sleep interval><sleep length><sleep measurement><sleep period><sleep polysomnography><sleep problem><sleep quantity><sleep time><sleepiness><stratify risk><tailored approach><therapy optimization><therapy prediction><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><tool><translation><treatment as usual><treatment effect><treatment optimization><treatment planning><treatment prediction><treatment response prediction><usual care>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

neomi A shah

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$718,857

FY 2026

Project Title

Application of Machine Learning to Identify Obstructive Sleep Apnea Subgroups at Risk for Atherosclerosis Progression and Cardiovascular Disease Events (OSA-GRANDE)

Grant Number:

5R01HL168897-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Obstructive sleep apnea (OSA) affects over one billion adults and is an independent risk factor for cardiovascular disease (CVD). Yet, in randomized clinical trials (RCT), treatment of OSA has failed to demonstrate a beneficial impact of continuous positive airway pressure (CPAP) on ...

Research Terms

<21+ years old><Active Follow-up><Address><Adherence><Adult><Adult Human><Affect><Age><Area><Atrial Fibrillation><Auricular Fibrillation><Big Data><BigData><CPAP><CPAP Ventilation><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Characteristics><Classification><Clinical><Collaborations><Continuous Positive Airway Pressure><Data><Data Bases><Data Set><Databases><Drowsiness><Dyslipidemias><Effectiveness><Electronic Health Record><Ensure><Environment><Event><Goals><Health Care Costs><Health Costs><Health system><Heart Vascular><Heart failure><Heterogeneity><Individual><Intervention><Machine Learning><Medicine><Modeling><Multimodal ML><Multimodal machine learning><NIH><National Institutes of Health><Obstructive Sleep Apnea><Outcome><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Personalized medical approach><Physicians><Polysomnography><Population><Prediction of Response to Therapy><Publications><Research><Risk><Risk Assessment><Risk Reduction><Sample Size><Sampling><Scientific Publication><Severities><Sleep><Sleep Disorders><Sleep Monitoring><Somnography><Somnolence><Subgroup><Syndrome, Sleep Apnea, Obstructive><Systematics><Techniques><Time><Translations><United States National Institutes of Health><Work><active followup><acute coronary syndrome><adulthood><ages><atherosclerosis risk><atherosclerotic risk><cardiac failure><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><care as usual><circulatory system><clinical decision-making><clinical practice><clinical relevance><clinical validation><clinically relevant><cohort><computer based prediction><coronary artery calcium scoring><coronary calcium scoring><data base><data collected in real world><data-driven model><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><ethnic diversity><ethnically diverse><experience><follow up><follow-up><followed up><followup><hazard><high risk><improved><individualized approach><individualized predictions><machine based learning><machine learning based method><machine learning method><machine learning methodologies><multi-modal data><multi-modal datasets><multidisciplinary><multimodal data><multimodal datasets><multimodal learning><new approaches><novel approaches><novel strategies><novel strategy><patient oriented outcomes><patient population><personalization of treatment><personalized approach><personalized medicine><personalized predictions><personalized therapy><personalized treatment><precision approach><precision medicine><precision-based medicine><predict therapeutic response><predict therapy response><predictive modeling><predictive tools><randomized, clinical trials><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><respiratory><risk prediction system><risk prediction tool><risk stratification><risk-reducing><sleep amount><sleep diseases><sleep duration><sleep dysfunction><sleep episode><sleep illness><sleep interval><sleep length><sleep measurement><sleep period><sleep polysomnography><sleep problem><sleep quantity><sleep time><sleepiness><stratify risk><tailored approach><therapy optimization><therapy prediction><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><tool><translation><treatment as usual><treatment effect><treatment optimization><treatment planning><treatment prediction><treatment response prediction><usual care>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KATHRYN J MOORE

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$717,206

FY 2026

Project Title

Long noncoding RNA regulation of Atherosclerotic Cardiovascular Disease

Grant Number:

5R01HL172335-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY Despite therapeutic advances, cardiovascular disease (CVD) remains the leading cause of death worldwide. There is thus an urgent need for innovation in CVD research and drug development. One class of molecules thought to hold particular promise is noncoding RNA, the importance of which was l...

Research Terms

<3-D><3-Dimensional><3D><ASCVD><Affect><Animal Model><Animal Models and Related Studies><Antisense Agent><Antisense Oligonucleotides><Apoplexy><Area><Arterial Fatty Streak><Arthritis><Atherogenicity><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Beta Proprotein Interleukin 1><Bioinformatics><Blood><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Blood Reticuloendothelial System><Blood Vessels><Brain Vascular Accident><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cancers><Cardiac artery><Cardiac infarction><Cardiovascular Diseases><Carotid Artery Plaques><Cas nuclease technology><Cathepsin C><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Function><Cell Nucleus><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cholesterol><Chromatin><Clinical><Clinical Data><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Code><Coding System><Coronary artery><Cytoplasm><DNA><Data><Deoxyribonucleic Acid><Development and Research><Dipeptidyl Aminopeptidase I><Dipeptidyl Peptidase I><Dipeptidyl Transferase><Disease><Disorder><Distal><Ectopic Expression><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Esteroproteases><Event><Extracellular Signal-Regulated Kinase Gene><Functional RNA><Gene Expression><Gene Transcription><Generalized Growth><Genes><Genetic Transcription><Genetics-Mutagenesis><Genome><Goals><Growth><Health><Heart artery><Human><Human Genome><IL-1 beta><IL-1 β><IL-1-b><IL-1β><IL1-Beta><IL1-β><IL1B Protein><IL1F2><IL1β><Immune><Immune response><Immunes><Immunoglobulin Enhancer-Binding Protein><In Vitro><Inflammasome><Inflammation><Inflammatory><Inflammatory Response><Innate Immune Response><Interleukin 1beta><Interleukin-1 beta><Interleukin-1β><Intracellular Communication and Signaling><Investigation><Knowledge><Ligands><Link><Lung Diseases><MAP Kinase Gene><MAPK><Macrophage><Malignant Neoplasms><Malignant Tumor><Marrow Neutrophil><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Messenger RNA><Mice><Mice Mammals><Mitogen-Activated Protein Kinase Gene><Modeling><Modern Man><Molecular><Murine><Mus><Mutagenesis><Mutagenesis Molecular Biology><Myeloid Cells><Myocardial Infarct><Myocardial Infarction><Mφ><NF-kB><NF-kappa B><NF-kappaB><NFKB><Names><Necrosis><Necrotic><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Non-Polyadenylated RNA><Noncoding RNA><Nontranslated RNA><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Nucleus><Pathological Constriction><Pathway interactions><Patients><Peptidases><Peptide Hydrolases><Phenotype><Plaque Instability><Plaque Rupture><Play><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Population><Precipitation><Preinterleukin 1 Beta><Process><Protease Gene><Proteases><Proteinases><Proteins><Proteolytic Enzymes><Pulmonary Diseases><Pulmonary Disorder><R & D><R&D><RNA><RNA Expression><RNA Gene Products><RNA Seq><RNA Splicing><RNA sequencing><RNAseq><Regulation><Research><Ribonucleic Acid><Role><Rupture><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Splicing><Stenosis><Sterility><Stimulus><Stroke><Subcellular Process><Systems Biology><Terminator Regions><Terminator Sequence><Testing><Therapeutic><Therapeutic Uses><Tissue Growth><Tissue Model><Transcript><Transcription><Transcription Factor NF-kB><Transcription Process><Transcriptional Terminator Regions><Translations><United States><Untranslated RNA><Work><antisense oligo><arthritic><atheromatosis><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic plaque rupture><atherosclerotic vascular disease><biological signal transduction><brain attack><cardiac infarct><cardiovascular disorder><cardiovascular health><carotid plaque><cerebral vascular accident><cerebrovascular accident><cohort><coronary attack><coronary infarct><coronary infarction><design><designing><diagnostic approach><diagnostic strategy><disease of the lung><disorder of the lung><drug development><epigenetically><extracellular><gain of function><genetic termination sequence><genetic terminator element><heart attack><heart infarct><heart infarction><host response><human model><human tissue><human whole genome><immune system response><immunoresponse><in silico><in vivo><innovate><innovation><innovative><kappa B Enhancer Binding Protein><loss of function><lung disorder><mRNA><malignancy><model of animal><model of human><molecular phenotype><mortality><mouse model><murine model><name><named><naming><neoplasm/cancer><neural inflammation><neuroinflammation><neuroinflammatory><neutrophil><new diagnostics><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><next generation diagnostics><noncoding><novel><novel diagnostics><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><nuclear factor kappa beta><ontogeny><pathway><plaque vulnerability><plaques in atherosclerosis><posttranscriptional><precipitations><protease C><research and development><response><social role><sterile><stroked><strokes><sudden cardiac death><termination sequence><therapeutic evaluation><therapeutic target><therapeutic testing><three dimensional><transcriptome sequencing><transcriptomic sequencing><translation><unstable plaque><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christine B Sethna

FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, MANHASSET, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$711,803

FY 2026

Project Title

Kids: Nocturnal Investigation into Glomerular Disease, Hypertension, and Transcriptomics (kNIGHT)

Grant Number:

5R01HL162912-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Children with proteinuric glomerulopathies are at considerable risk for cardiovascular disease. In addition to the high prevalence of traditional cardiovascular disease risk factors in this population, more than half of children with proteinuric glomerulopathies experience n...

Research Terms

<0-11 years old><21+ years old><6 year old><6 years of age><ASCVD><Adult><Adult Human><Aeroseb-HC><Ambulatory Blood Pressure Monitoring><American Heart Association><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Bioinformatics><Blood Pressure><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cetacort><Child><Child Health><Child Youth><Children (0-21)><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Data><Clinical Markers><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Data><Dermacort><Development><Disease><Disease Marker><Disease Outcome><Disorder><Dysfunction><Dyslipidemias><Echocardiogram><Echocardiography><Eldecort><Enrollment><Fatty Acid Metabolism Pathway><Functional disorder><Funding><Future><Gene Expression><Genes><Genomics><Glomerular disease><Goals><Guide prevention><Health><Heart Vascular><High Prevalence><Home><Hour><Hydrocortisone><Hydrocortone><Hypertension><Hytone><Inflammation><Intake><Investigation><Kidney><Kidney Urinary System><Knowledge><LV Mass><Laboratories><Left><Left Ventricular Dysfunction><Left Ventricular Hypertrophy><Left Ventricular Mass><Link><Lipids><Longitudinal Studies><Longitudinal Surveys><Longitudinal observational study><Machine Learning><Measurement><Measures><Metabolic><Methodology><Molecular><Morbidity><Multiomic Data><NIH><Na element><National Institutes of Health><Nephrotic Syndrome><Night-time Hypertension><Nocturnal Hypertension><Nutracort><Organ><Orphan Disease><Outcome><Pathologic><Pathway interactions><Patients><Pattern><Phenotype><Physical activity><Physiologic pulse><Physiopathology><Population><Prevention><Proctocort><Proteomics><Pulse><Questionnaires><Rare Diseases><Rare Disorder><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Risk><Risk Factors><Risk Marker><Risk Reduction><Salivary><Sleep><Sleep Apnea><Sleep Apnea Syndromes><Sleep Hypopnea><Sleep-Disordered Breathing><Sodium><Systems Biology><Time><Transthoracic Echocardiography><United States National Institutes of Health><Validation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Ventricular><Whole Blood><Work><actigraph><actigraphy><adulthood><age 6><age 6 years><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><chronic kidney disease><circadian><circulatory system><clinical biomarkers><clinical predictors><clinically useful biomarkers><cohort><computer based prediction><data integration><design><designing><developmental><differential expression><differentially expressed><enroll><experience><fatty acid metabolism><global gene expression><global transcription profile><heart sonography><high blood pressure><high risk><high risk group><high risk individual><high risk people><high risk population><homes><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><indexing><innovate><innovation><innovative><kids><left ventricle abnormality><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><machine based learning><machine learning based method><machine learning method><machine learning methodologies><metabolism measurement><metabolomics><metabonomics><molecular biomarker><molecular marker><mortality><multiple omic data><novel><observational cohort study><orphan disorder><pathophysiology><pathway><patient centered><patient oriented><precision medicine><precision-based medicine><predictive biological marker><predictive biomarkers><predictive marker><predictive modeling><predictive molecular biomarker><quality of sleep><randomized, clinical trials><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><renal><risk predictor><risk predictors><risk-reducing><six year old><six years of age><sleep amount><sleep duration><sleep episode><sleep interval><sleep length><sleep period><sleep quality><sleep quantity><sleep time><sleep-related breathing disorder><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><transcriptional differences><transcriptome><transcriptomics><validations><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amy Christine Arnold

PENNSYLVANIA STATE UNIV HERSHEY MED CTR, HERSHEY, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$706,467

FY 2026

Project Title

Angiotensin-(1-7) and Cardiovascular Derangements in Obesity Hypertension

Grant Number:

5R01HL170140-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Obesity is a global epidemic that is associated with sympathetic overactivation, endothelial dysfunction, and insulin resistance; all of which can contribute to hypertension development. Despite well-established clinical associations, the mechanisms connecting obesity with hypertensi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alfredo Gamboa

PENNSYLVANIA STATE UNIV HERSHEY MED CTR, HERSHEY, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$706,467

FY 2026

Project Title

Angiotensin-(1-7) and Cardiovascular Derangements in Obesity Hypertension

Grant Number:

5R01HL170140-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Obesity is a global epidemic that is associated with sympathetic overactivation, endothelial dysfunction, and insulin resistance; all of which can contribute to hypertension development. Despite well-established clinical associations, the mechanisms connecting obesity with hypertensi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARK MERCOLA

STANFORD UNIVERSITY, STANFORD, CA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$695,123

FY 2026

Project Title

Unraveling Proteasome Inhibitor-Induced Cardiovascular Toxicity through Integrative Multiomics

Grant Number:

5R01HL176822-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Proteasome inhibitors (PIs) represent novel cancer therapeutics highly effective in treating hematologic malignancies and have remarkably improved cancer survival rates. However, the utilization of PIs, particularly carfilzomib (CFZ), is largely hampered by substantial cardiovascular...

Research Terms

<3-D><3-Dimensional><3D><Adverse Experience><Adverse event><Algorithms><Alternate Splicing><Alternative RNA Splicing><Alternative Splicing><Antisense Agent><Antisense Oligonucleotides><Aorta><Arrhythmia><Assay><Autoregulation><BP reduction><Bioassay><Biological Assay><Biology><Blood Pressure Monitors><Blood Vessels><CRISPR><CRISPR activation><CRISPR activator><CRISPR based activation><CRISPR gene activation><CRISPR interference><CRISPR transcription activation><CRISPR transcriptional activation><CRISPR-Cas-9-mediated gene activation><CRISPR-based gene activation><CRISPR-dCAS9 Activator><CRISPR-dCas9-mediated repression><CRISPR-mediated transcriptional activation><CRISPR/CAS9 activation><CRISPR/CAS9 gene activation><CRISPR/Cas system><CRISPR/dCas9 activation><CRISPR/dCas9 interference><CRISPR/dCas9-based transcriptional activation><CRISPR/dCas9-mediated transcriptional inhibition><CRISPRa><CRISPRi><Cancer Patient><Cancers><Cardiac><Cardiac Arrhythmia><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cell Line><CellLine><Cells><Ch'i><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats><Clustered Regularly Interspaced Short Palindromic Repeats interference><Continuous Sphygmomanometers><Coronary><DNA Therapy><Data><Development><Disease><Disorder><Down-Regulation><Dysfunction><Effectiveness><Endothelial Cells><Event><FDA approved><Functional disorder><Gene Transfer Clinical><Generations><Genes><Genetic Intervention><Genomics><Heart Arrhythmias><Heart Hypertrophy><Heart Vascular><Heart failure><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematopoietic Cancer><Heterograft><Heterologous Transplantation><Homeostasis><Human><Hypertension><Isoforms><Label><Lead><Leiomyocyte><Life><Link><Luciferase Immunologic><Luciferases><Malignant Hematologic Neoplasm><Malignant Neoplasms><Malignant Tumor><Maps><Measures><Mediating><Mice><Mice Mammals><Microcirculation><Modern Man><Molecular Fingerprinting><Molecular Profiling><Multiple Myeloma><Murine><Mus><Muscle Cells><Myocardial depression><Myocardial dysfunction><Myocytes><NOD/SCID mouse><Newly Diagnosed><Non-Polyadenylated RNA><Oncology><Oncology Cancer><Pathogenicity><Pathology><Pattern><Pb element><Phenotype><Physiological Homeostasis><Physiopathology><Piezo 1><Piezo 1 ion channel><Piezo1><Plasma-Cell Myeloma><Predictive Factor><Proteasome Inhibitor><Protein Isoforms><Qi><RNA><RNA Gene Products><RNA Splicing><Refractory><Regulation><Relapse><Repression><Resolution><Ribonucleic Acid><Role><Shapes><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Splicing><Strains Cell Lines><Survival Rate><System><Techniques><Therapeutic><Thrombosis><Time><Tissue Engineering><Toxic effect><Toxicities><Treatment Efficacy><Validation><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular Smooth Muscle><Xenograft><Xenograft procedure><Xenotransplantation><activating CRISPR technology><antisense oligo><bioengineered tissue><blood pressure reduction><blood vessel disorder><cancer survival><cardiac dysfunction><cardiac failure><cardiac function><cardiac hypertrophy><cardioprotectant><cardioprotection><cardioprotective><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><cell type><circulatory system><cultured cell line><deep learning><deep learning algorithm><deep learning method><deep learning strategy><design><designing><developmental><differential expression><differentially expressed><disease phenotype><engineered tissue><engineered vascular tissue><engineered vascularized tissue><experiment><experimental research><experimental study><experiments><function of the heart><gene repair therapy><gene therapy><gene-based therapy><genetic therapy><genomic therapy><heart dysfunction><heart function><heavy metal Pb><heavy metal lead><hiPSC><high blood pressure><human iPS><human iPSC><human induced pluripotent cell><human induced pluripotent stem cells><human inducible pluripotent stem cells><human inducible stem cells><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><iPS><iPS biology><iPSC><iPSC biology><iPSC technology><iPSCs><improved><induced human pluripotent stem cells><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cell biology><induced pluripotent stem cell technology><inducible pluripotent cell><inducible pluripotent stem cell><insight><intervention efficacy><lower BP><lower blood pressure><lowers blood pressure><malignancy><molecular profile><molecular signature><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mouse model><multidisciplinary><multiomics><multiple omics><murine model><myeloma><myelomatosis><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><panomics><pathophysiology><prevent><preventing><protective effect><reduce BP><reduce blood pressure><reduction in BP><reduction in blood pressure><repressing CRISPR-dCas9 system><resolutions><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><stem cell technology><therapeutic efficacy><therapeutically effective><therapy efficacy><three dimensional><thrombotic><thrombotic disease><thrombotic disorder><transcriptional differences><validations><vascular><vascular dysfunction><vascular tissue engineering><vasculopathy><xeno-transplant><xeno-transplantation>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph C. Wu

STANFORD UNIVERSITY, STANFORD, CA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$695,123

FY 2026

Project Title

Unraveling Proteasome Inhibitor-Induced Cardiovascular Toxicity through Integrative Multiomics

Grant Number:

5R01HL176822-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Proteasome inhibitors (PIs) represent novel cancer therapeutics highly effective in treating hematologic malignancies and have remarkably improved cancer survival rates. However, the utilization of PIs, particularly carfilzomib (CFZ), is largely hampered by substantial cardiovascular...

Research Terms

<3-D><3-Dimensional><3D><Adverse Experience><Adverse event><Algorithms><Alternate Splicing><Alternative RNA Splicing><Alternative Splicing><Antisense Agent><Antisense Oligonucleotides><Aorta><Arrhythmia><Assay><Autoregulation><BP reduction><Bioassay><Biological Assay><Biology><Blood Pressure Monitors><Blood Vessels><CRISPR><CRISPR activation><CRISPR activator><CRISPR based activation><CRISPR gene activation><CRISPR interference><CRISPR transcription activation><CRISPR transcriptional activation><CRISPR-Cas-9-mediated gene activation><CRISPR-based gene activation><CRISPR-dCAS9 Activator><CRISPR-dCas9-mediated repression><CRISPR-mediated transcriptional activation><CRISPR/CAS9 activation><CRISPR/CAS9 gene activation><CRISPR/Cas system><CRISPR/dCas9 activation><CRISPR/dCas9 interference><CRISPR/dCas9-based transcriptional activation><CRISPR/dCas9-mediated transcriptional inhibition><CRISPRa><CRISPRi><Cancer Patient><Cancers><Cardiac><Cardiac Arrhythmia><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cell Line><CellLine><Cells><Ch'i><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats><Clustered Regularly Interspaced Short Palindromic Repeats interference><Continuous Sphygmomanometers><Coronary><DNA Therapy><Data><Development><Disease><Disorder><Down-Regulation><Dysfunction><Effectiveness><Endothelial Cells><Event><FDA approved><Functional disorder><Gene Transfer Clinical><Generations><Genes><Genetic Intervention><Genomics><Heart Arrhythmias><Heart Hypertrophy><Heart Vascular><Heart failure><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematopoietic Cancer><Heterograft><Heterologous Transplantation><Homeostasis><Human><Hypertension><Isoforms><Label><Lead><Leiomyocyte><Life><Link><Luciferase Immunologic><Luciferases><Malignant Hematologic Neoplasm><Malignant Neoplasms><Malignant Tumor><Maps><Measures><Mediating><Mice><Mice Mammals><Microcirculation><Modern Man><Molecular Fingerprinting><Molecular Profiling><Multiple Myeloma><Murine><Mus><Muscle Cells><Myocardial depression><Myocardial dysfunction><Myocytes><NOD/SCID mouse><Newly Diagnosed><Non-Polyadenylated RNA><Oncology><Oncology Cancer><Pathogenicity><Pathology><Pattern><Pb element><Phenotype><Physiological Homeostasis><Physiopathology><Piezo 1><Piezo 1 ion channel><Piezo1><Plasma-Cell Myeloma><Predictive Factor><Proteasome Inhibitor><Protein Isoforms><Qi><RNA><RNA Gene Products><RNA Splicing><Refractory><Regulation><Relapse><Repression><Resolution><Ribonucleic Acid><Role><Shapes><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Splicing><Strains Cell Lines><Survival Rate><System><Techniques><Therapeutic><Thrombosis><Time><Tissue Engineering><Toxic effect><Toxicities><Treatment Efficacy><Validation><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular Smooth Muscle><Xenograft><Xenograft procedure><Xenotransplantation><activating CRISPR technology><antisense oligo><bioengineered tissue><blood pressure reduction><blood vessel disorder><cancer survival><cardiac dysfunction><cardiac failure><cardiac function><cardiac hypertrophy><cardioprotectant><cardioprotection><cardioprotective><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><cell type><circulatory system><cultured cell line><deep learning><deep learning algorithm><deep learning method><deep learning strategy><design><designing><developmental><differential expression><differentially expressed><disease phenotype><engineered tissue><engineered vascular tissue><engineered vascularized tissue><experiment><experimental research><experimental study><experiments><function of the heart><gene repair therapy><gene therapy><gene-based therapy><genetic therapy><genomic therapy><heart dysfunction><heart function><heavy metal Pb><heavy metal lead><hiPSC><high blood pressure><human iPS><human iPSC><human induced pluripotent cell><human induced pluripotent stem cells><human inducible pluripotent stem cells><human inducible stem cells><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><iPS><iPS biology><iPSC><iPSC biology><iPSC technology><iPSCs><improved><induced human pluripotent stem cells><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cell biology><induced pluripotent stem cell technology><inducible pluripotent cell><inducible pluripotent stem cell><insight><intervention efficacy><lower BP><lower blood pressure><lowers blood pressure><malignancy><molecular profile><molecular signature><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mouse model><multidisciplinary><multiomics><multiple omics><murine model><myeloma><myelomatosis><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><panomics><pathophysiology><prevent><preventing><protective effect><reduce BP><reduce blood pressure><reduction in BP><reduction in blood pressure><repressing CRISPR-dCas9 system><resolutions><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><stem cell technology><therapeutic efficacy><therapeutically effective><therapy efficacy><three dimensional><thrombotic><thrombotic disease><thrombotic disorder><transcriptional differences><validations><vascular><vascular dysfunction><vascular tissue engineering><vasculopathy><xeno-transplant><xeno-transplantation>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Feifan Liu

UNIV OF MASSACHUSETTS MED SCH WORCESTER, WORCESTER, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$691,991

FY 2026

Project Title

AI2Equity: AI Integrating Social Determinants of Health to Advance Health Equity in Cardiovascular Risk Prediction

Grant Number:

5R01HL171599-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/20/2024

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

AI2Equity: AI Integrating SDOH Data to Advance Health Equity in Cardiovascular Risk Prediction Abstract Disparities in cardiovascular disease (CVD) risk exist among racial/ethnic minorities and lower socioeconomic groups, where social determinants of health (SDOH) and structural social factors subst...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christine Kee Liu

PALO ALTO VETERANS INSTIT FOR RESEARCH, PALO ALTO, CA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$690,409

FY 2026

Project Title

Deprescribing Cardiovascular Medications among Persons with and without Alzheimer's Disease and Related Dementias in Long-Term Care

Grant Number:

5R01AG062568-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2019

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT The use of preventive cardiovascular medications among nursing home residents with Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) presents a clinical conundrum. On one hand, the majority of nursing home residents with AD/ADRD have a history of cardio...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD and related dementia><AD dementia><AD patients><AD related dementia><ADRD><Acetylsalicylic Acid><Address><Admission><Admission activity><Adult><Adult Human><Adverse Experience><Adverse event><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's patient><Alzheimers Dementia><Amentia><Analgesic Management><Anti-Hypertensive Agents><Anti-Hypertensive Drugs><Anti-Hypertensives><Anticoagulant Agents><Anticoagulant Drugs><Anticoagulants><Apoplexy><Aspirin><Atrial Fibrillation><Auricular Fibrillation><Bar Codes><Bleeding><Blood Platelets><Brain Vascular Accident><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Chronic><Clinical><Clinical Trials><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><D-Glucose><Data><Dementia><Descriptive Epidemiology><Dextrose><Disturbance in cognition><Dose><Drugs><Epidemiology><Event><Frequencies><Glucose><Goals><Grant><Heart Vascular><Hemorrhage><History><Hypotensive Agent><Hypotensive Drugs><Impaired cognition><Impairment><Incidence><Inpatients><Laboratories><Link><Long-Term Care><Marrow platelet><Measurement><Medicare/Medicaid><Medication><Medication Management><Mentors><Methods><Myocardial Infarct><Myocardial Infarction><Nursing Homes><Observation in research><Out-patients><Outcome><Outpatients><Paper><Patients><Persons><Pharmaceutical Preparations><Pharmacologic Management><Physical Function><Platelets><Population><Preventive><Primary Prevention><Primary Senile Degenerative Dementia><Process><Provider><Publications><Randomized, Controlled Trials><Recording of previous events><Regimen><Research><Risk><Science><Scientific Publication><Scientist><Secondary Prevention><Stroke><Structure><Thrombocytes><Uncertainty><Veterans Health Administration><Veterans Health Affairs><Work><above age 65><acute coronary syndrome><adulthood><adverse event risk><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><anti-hypertension><barcode><blood loss><blood thinner><brain attack><cardiac infarct><cardioprotectant><cardioprotection><cardioprotective><cardiovascular disorder><career><cerebral vascular accident><cerebrovascular accident><circulatory system><cognitive dysfunction><cognitive loss><cohort><conference><convention><coronary attack><coronary event><coronary infarct><coronary infarction><decision-making capacity><doubt><drug/agent><epidemiologic><epidemiological><extended care><functional outcomes><heart attack><heart infarct><heart infarction><high risk><histories><human old age (65+)><medication administration><medication therapy management><mortality><novel><nursing home><over 65 years><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><primary degenerative dementia><randomized control trial><senile dementia of the Alzheimer type><statistics><stroked><strokes><success><summit><symposia><symposium><thrombopoiesis inhibitor><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michelle Christina Odden

PALO ALTO VETERANS INSTIT FOR RESEARCH, PALO ALTO, CA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$690,409

FY 2026

Project Title

Deprescribing Cardiovascular Medications among Persons with and without Alzheimer's Disease and Related Dementias in Long-Term Care

Grant Number:

5R01AG062568-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2019

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT The use of preventive cardiovascular medications among nursing home residents with Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) presents a clinical conundrum. On one hand, the majority of nursing home residents with AD/ADRD have a history of cardio...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD and related dementia><AD dementia><AD patients><AD related dementia><ADRD><Acetylsalicylic Acid><Address><Admission><Admission activity><Adult><Adult Human><Adverse Experience><Adverse event><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's patient><Alzheimers Dementia><Amentia><Analgesic Management><Anti-Hypertensive Agents><Anti-Hypertensive Drugs><Anti-Hypertensives><Anticoagulant Agents><Anticoagulant Drugs><Anticoagulants><Apoplexy><Aspirin><Atrial Fibrillation><Auricular Fibrillation><Bar Codes><Bleeding><Blood Platelets><Brain Vascular Accident><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Chronic><Clinical><Clinical Trials><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><D-Glucose><Data><Dementia><Descriptive Epidemiology><Dextrose><Disturbance in cognition><Dose><Drugs><Epidemiology><Event><Frequencies><Glucose><Goals><Grant><Heart Vascular><Hemorrhage><History><Hypotensive Agent><Hypotensive Drugs><Impaired cognition><Impairment><Incidence><Inpatients><Laboratories><Link><Long-Term Care><Marrow platelet><Measurement><Medicare/Medicaid><Medication><Medication Management><Mentors><Methods><Myocardial Infarct><Myocardial Infarction><Nursing Homes><Observation in research><Out-patients><Outcome><Outpatients><Paper><Patients><Persons><Pharmaceutical Preparations><Pharmacologic Management><Physical Function><Platelets><Population><Preventive><Primary Prevention><Primary Senile Degenerative Dementia><Process><Provider><Publications><Randomized, Controlled Trials><Recording of previous events><Regimen><Research><Risk><Science><Scientific Publication><Scientist><Secondary Prevention><Stroke><Structure><Thrombocytes><Uncertainty><Veterans Health Administration><Veterans Health Affairs><Work><above age 65><acute coronary syndrome><adulthood><adverse event risk><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><anti-hypertension><barcode><blood loss><blood thinner><brain attack><cardiac infarct><cardioprotectant><cardioprotection><cardioprotective><cardiovascular disorder><career><cerebral vascular accident><cerebrovascular accident><circulatory system><cognitive dysfunction><cognitive loss><cohort><conference><convention><coronary attack><coronary event><coronary infarct><coronary infarction><decision-making capacity><doubt><drug/agent><epidemiologic><epidemiological><extended care><functional outcomes><heart attack><heart infarct><heart infarction><high risk><histories><human old age (65+)><medication administration><medication therapy management><mortality><novel><nursing home><over 65 years><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><primary degenerative dementia><randomized control trial><senile dementia of the Alzheimer type><statistics><stroked><strokes><success><summit><symposia><symposium><thrombopoiesis inhibitor><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bing Yu

UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$686,867

FY 2026

Project Title

Molecular Determinants of Atherosclerotic Cardiovascular Disease in Multi-ethnic Populations

Grant Number:

5R01HL168683-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of death worldwide. Understanding the process of atherosclerosis and its progression is essential to decrease ASCVD burden. Despite successful identification of genetic variants and clinical risk factors related to ASCVD...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lindsay Fernandez-Rhodes

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$685,106

FY 2026

Project Title

Leveraging Hispanic/Latino diversity to map and characterize cardiovascular disease loci

Grant Number:

5R01HL163262-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/16/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among US Hispanic or Latino (H/L) populations. H/Ls are a relatively young population and experience heightened disparities in risk for most CVD risk factors, including obesity, type 2 diabetes (T2D), dyslipidemia, an...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mariaelisa Graff

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$685,106

FY 2026

Project Title

Leveraging Hispanic/Latino diversity to map and characterize cardiovascular disease loci

Grant Number:

5R01HL163262-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/16/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among US Hispanic or Latino (H/L) populations. H/Ls are a relatively young population and experience heightened disparities in risk for most CVD risk factors, including obesity, type 2 diabetes (T2D), dyslipidemia, an...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

William Adam Grobman

NORTHWESTERN UNIVERSITY AT CHICAGO, CHICAGO, IL

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$684,824

FY 2026

Project Title

Stress reactivity and adverse placental and pregnancy outcomes

Grant Number:

5R01HL168409-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/19/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT A growing number of studies has implicated maternal stress as an explanation for adverse pregnancy outcomes (APOs). Most studies that have explored the relationship between stress and APOs have focused solely on prenatal exposure to stressors, and not the life course. Moreover, some women m...

Research Terms

<0-11 years old><Aeroseb-HC><Affective><Blood Pressure><Blood Vessels><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cells><Cells Placenta-Tissue><Cellular Immune Function><Cetacort><Child><Child Youth><Children (0-21)><Chronic><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Decidua Basalis><Dermacort><Ecological momentary assessment><Education><Educational aspects><Eldecort><Environment><Event><Exposure Assessment><Exposure to><Face><Frequencies><Future><Gestation><Goals><Health><Health behavior><Heart Vascular><Histologic><Histologically><Histology><Hydrocortisone><Hydrocortone><Hypophysis><Hypophysis Cerebri><Hypothalamic structure><Hypothalamus><Hytone><Immune system><Individual><Inflammation><Laboratories><Lesion><Life><Life Cycle><Life Cycle Stages><Maternal placenta><Measurement><Measures><Mediating><Mothers><Neighborhoods><Neuroendocrine><Neuroendocrine System><Neurosecretory Systems><Normal Placentoma><Nulliparas><Nulliparity><Nulliparous><Nutracort><Outcome><Participant><Physiologic><Physiological><Pituitary><Pituitary Gland><Pituitary Nervous System><Placenta><Placenta Embryonic Tissue><Placentome><Play><Population><Pregnancy><Pregnancy Outcome><Pregnant Women><Proctocort><Psychologic Stress><Psychological Stress><Reaction><Reporting><Research><Research Resources><Resources><Risk><Salivary><Severities><Stress><Stressful Event><Testing><Time><Woman><adverse pregnancy outcome><biological adaptation to stress><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><circulatory system><coping><expectant mother><expectant women><expecting mother><expecting women><experience><exposed in utero><exposure analysis><exposure evaluation><exposure measurement><exposure profiling><exposure survey><faces><facial><fetal exposure><fetal stress><health related behavior><heart rate variability><hypothalamic><immune function><in utero exposure><individuals who are pregnant><insight><intra-uterine environmental exposure><intrauterine environmental exposure><kids><later in life><later life><life course><maternal stress><mid-pregnancy><mortality><negative affect><negative affectivity><neonatal morbidity><newborn morbidity><people who are pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal exposure><prenatal stress><prenatally exposed><psychologic><psychological><reactioncrisis><response><social stresses><social stressor><stress reactivity><stress response><stressreaction><stressed mothers><stressful experience><stressful life event><stressful life experience><stressor><those who are pregnant><vascular><women who are pregnant><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kiarri N Kershaw

NORTHWESTERN UNIVERSITY AT CHICAGO, CHICAGO, IL

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$684,824

FY 2026

Project Title

Stress reactivity and adverse placental and pregnancy outcomes

Grant Number:

5R01HL168409-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/19/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT A growing number of studies has implicated maternal stress as an explanation for adverse pregnancy outcomes (APOs). Most studies that have explored the relationship between stress and APOs have focused solely on prenatal exposure to stressors, and not the life course. Moreover, some women m...

Research Terms

<0-11 years old><Aeroseb-HC><Affective><Blood Pressure><Blood Vessels><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cells><Cells Placenta-Tissue><Cellular Immune Function><Cetacort><Child><Child Youth><Children (0-21)><Chronic><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Decidua Basalis><Dermacort><Ecological momentary assessment><Education><Educational aspects><Eldecort><Environment><Event><Exposure Assessment><Exposure to><Face><Frequencies><Future><Gestation><Goals><Health><Health behavior><Heart Vascular><Histologic><Histologically><Histology><Hydrocortisone><Hydrocortone><Hypophysis><Hypophysis Cerebri><Hypothalamic structure><Hypothalamus><Hytone><Immune system><Individual><Inflammation><Laboratories><Lesion><Life><Life Cycle><Life Cycle Stages><Maternal placenta><Measurement><Measures><Mediating><Mothers><Neighborhoods><Neuroendocrine><Neuroendocrine System><Neurosecretory Systems><Normal Placentoma><Nulliparas><Nulliparity><Nulliparous><Nutracort><Outcome><Participant><Physiologic><Physiological><Pituitary><Pituitary Gland><Pituitary Nervous System><Placenta><Placenta Embryonic Tissue><Placentome><Play><Population><Pregnancy><Pregnancy Outcome><Pregnant Women><Proctocort><Psychologic Stress><Psychological Stress><Reaction><Reporting><Research><Research Resources><Resources><Risk><Salivary><Severities><Stress><Stressful Event><Testing><Time><Woman><adverse pregnancy outcome><biological adaptation to stress><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><circulatory system><coping><expectant mother><expectant women><expecting mother><expecting women><experience><exposed in utero><exposure analysis><exposure evaluation><exposure measurement><exposure profiling><exposure survey><faces><facial><fetal exposure><fetal stress><health related behavior><heart rate variability><hypothalamic><immune function><in utero exposure><individuals who are pregnant><insight><intra-uterine environmental exposure><intrauterine environmental exposure><kids><later in life><later life><life course><maternal stress><mid-pregnancy><mortality><negative affect><negative affectivity><neonatal morbidity><newborn morbidity><people who are pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal exposure><prenatal stress><prenatally exposed><psychologic><psychological><reactioncrisis><response><social stresses><social stressor><stress reactivity><stress response><stressreaction><stressed mothers><stressful experience><stressful life event><stressful life experience><stressor><those who are pregnant><vascular><women who are pregnant><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Craig J. Goergen

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$677,985

FY 2026

Project Title

Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

Grant Number:

5R01HL167969-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/23/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Duchenne and Becker muscular dystrophy (DMD/BMD) are devastating diseases with no cure resulting in loss of ambulation, respiratory failure, cardiomyopathy, and premature death. Dystrophin associated cardiomyopathy (defined here as CM) is the leading cause of death in DMD/BM...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kan N Hor

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$677,985

FY 2026

Project Title

Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

Grant Number:

5R01HL167969-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/23/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Duchenne and Becker muscular dystrophy (DMD/BMD) are devastating diseases with no cure resulting in loss of ambulation, respiratory failure, cardiomyopathy, and premature death. Dystrophin associated cardiomyopathy (defined here as CM) is the leading cause of death in DMD/BM...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Guang Lin

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$677,985

FY 2026

Project Title

Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

Grant Number:

5R01HL167969-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/23/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Duchenne and Becker muscular dystrophy (DMD/BMD) are devastating diseases with no cure resulting in loss of ambulation, respiratory failure, cardiomyopathy, and premature death. Dystrophin associated cardiomyopathy (defined here as CM) is the leading cause of death in DMD/BM...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Larry W. Markham

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$677,985

FY 2026

Project Title

Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

Grant Number:

5R01HL167969-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/23/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Duchenne and Becker muscular dystrophy (DMD/BMD) are devastating diseases with no cure resulting in loss of ambulation, respiratory failure, cardiomyopathy, and premature death. Dystrophin associated cardiomyopathy (defined here as CM) is the leading cause of death in DMD/BM...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jonathan Harvey Soslow

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$677,985

FY 2026

Project Title

Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

Grant Number:

5R01HL167969-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/23/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Duchenne and Becker muscular dystrophy (DMD/BMD) are devastating diseases with no cure resulting in loss of ambulation, respiratory failure, cardiomyopathy, and premature death. Dystrophin associated cardiomyopathy (defined here as CM) is the leading cause of death in DMD/BM...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kevin James Cummings

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$664,632

FY 2026

Project Title

SIDS, failed autoresuscitation, and a novel serotonergic brainstem-cerebellar circuit

Grant Number:

5R01HL179313-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The Sudden Infant Death Syndrome (SIDS) remains the leading cause of death in the post-neonatal period. Rare traces from infants who died of SIDS indicate cardiovascular collapse during autoresuscitation, the integrated cardiovascular and sympathetic response necessary to sustain life in severely hy...

Research Terms

<5-HT><5-HT Receptors><5-HT pathway><5-HT system><5-HT(2A) Receptor><5-HT-2A Gene><5-HT2A><5-HT2A Receptor><5-Hydroxytryptamine><5-Hydroxytryptamine (Serotonin) Receptor 2A Gene><5-Hydroxytryptamine Receptor 2A><5-Hydroxytryptamine Receptor 2A Gene><5-Hydroxytryptamine Receptors><5HT><Adoption><Affect><Animal Model><Animal Models and Related Studies><BP homeostasis><BP regulation><Back to Sleep><Binding><Biological><Biological Markers><Blood Diseases><Blood Pressure><Body Tissues><Brain><Brain Nervous System><Brain Stem><Brainstem><CRE Recombinase><Cardiac Chronotropism><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Causality><Cause of Death><Cell Body><Cell Death><Cells><Cerebellar Cortex><Cerebellum><Cessation of life><Clinical><Common Rat Strains><Cot Death><Crib Death><DREADDs><Death><Defect><Development><Dysfunction><Encephalon><Enteramine><Enterobacteria phage P1 Cre recombinase><Environmental Factor><Environmental Risk Factor><Etiology><Exposure to><Fiber><Functional disorder><HTR2><HTR2 Gene><HTR2A><HTR2A gene><Health><Heart Diseases><Heart Rate><Heart Vascular><Hematologic Diseases><Hematological Disease><Hematological Disorder><Hippophaine><Human><Hypoxia><Hypoxic><Impairment><Incidence><Individual><Infant><Infant Mortality><Infant Mortality Total><Injury><Knowledge><Life><Lung Diseases><Medial><Mediating><Medulla Oblongata><Mission><Modern Man><Molecular Interaction><Myelencephalon><NHLBI><National Heart, Lung, and Blood Institute><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Nucleus Tractus Solitarii><Nucleus fastigii><Nucleus solitarius><O element><O2 element><Olives><Olives - dietary><Outcome><Oxygen><Oxygen Deficiency><Pathology><Physiopathology><Predisposition><Prevention><Process><Pulmonary Diseases><Pulmonary Disorder><Purkinje Cells><Purkinje's Corpuscles><Rat><Rats Mammals><Rattus><Receptor Protein><Receptor Signaling><Recovery><Research><Research Support><Risk Factors><Rodent><Rodentia><Rodents Mammals><Role><Running><SIDS><Safe Sleep><Safe to Sleep Campaign><Serotonergic System><Serotonin><Serotonin 2A Receptor><Serotonin 5-HT-2 Receptor Gene><Serotonin 5-HT-2A Receptor><Serotonin Receptor 5-HT2A><Solitary Nucleus><Source><Sudden Death><Sudden Infant Death><Sudden Unexpected Infant Death><Sudden infant death syndrome><Susceptibility><System><Testing><Time><Tissues><Trees><bacteriophage P1 recombinase Cre><bio-markers><biologic><biologic marker><biomarker><blood disorder><blood pressure homeostasis><blood pressure regulation><cardiovascular collapse><cardiovascular function><causation><cerebellar Purkinje cell><circulatory system><compare to control><comparison control><critical period><death among infants><death in first year of life><death in infancy><death in infants><designer receptors exclusively activated by designer drugs><developmental><disease causation><disease of the lung><disorder of the lung><environmental risk><evidence base><experience><experiment><experimental research><experimental study><experiments><fastigial nucleus><fiber cell><heart disorder><infant animal><infant death><infant demise><infantile death><injuries><innovate><innovation><innovative><lung disorder><model of animal><mortality in infants><necrocytosis><neonatal period><neural control><neural regulation><neuromodulation><neuromodulatory><neuronal><neuroregulation><novel><pathophysiology><pharmacologic><post-natal development><post-natal intermittent hypoxia><postnatal><postnatal development><prenatal><prevent><preventing><prophylactic><pup><receptor><receptor binding><receptor bound><receptor expression><regulate BP><regulate blood pressure><response><serotonergic pathway><serotonin pathway><serotonin receptor><serotonin system><social role><solitary tract nucleus><translational opportunities><translational potential><unborn>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ROBIN Lynn HAYNES

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$664,632

FY 2026

Project Title

SIDS, failed autoresuscitation, and a novel serotonergic brainstem-cerebellar circuit

Grant Number:

5R01HL179313-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The Sudden Infant Death Syndrome (SIDS) remains the leading cause of death in the post-neonatal period. Rare traces from infants who died of SIDS indicate cardiovascular collapse during autoresuscitation, the integrated cardiovascular and sympathetic response necessary to sustain life in severely hy...

Research Terms

<5-HT><5-HT Receptors><5-HT pathway><5-HT system><5-HT(2A) Receptor><5-HT-2A Gene><5-HT2A><5-HT2A Receptor><5-Hydroxytryptamine><5-Hydroxytryptamine (Serotonin) Receptor 2A Gene><5-Hydroxytryptamine Receptor 2A><5-Hydroxytryptamine Receptor 2A Gene><5-Hydroxytryptamine Receptors><5HT><Adoption><Affect><Animal Model><Animal Models and Related Studies><BP homeostasis><BP regulation><Back to Sleep><Binding><Biological><Biological Markers><Blood Diseases><Blood Pressure><Body Tissues><Brain><Brain Nervous System><Brain Stem><Brainstem><CRE Recombinase><Cardiac Chronotropism><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Causality><Cause of Death><Cell Body><Cell Death><Cells><Cerebellar Cortex><Cerebellum><Cessation of life><Clinical><Common Rat Strains><Cot Death><Crib Death><DREADDs><Death><Defect><Development><Dysfunction><Encephalon><Enteramine><Enterobacteria phage P1 Cre recombinase><Environmental Factor><Environmental Risk Factor><Etiology><Exposure to><Fiber><Functional disorder><HTR2><HTR2 Gene><HTR2A><HTR2A gene><Health><Heart Diseases><Heart Rate><Heart Vascular><Hematologic Diseases><Hematological Disease><Hematological Disorder><Hippophaine><Human><Hypoxia><Hypoxic><Impairment><Incidence><Individual><Infant><Infant Mortality><Infant Mortality Total><Injury><Knowledge><Life><Lung Diseases><Medial><Mediating><Medulla Oblongata><Mission><Modern Man><Molecular Interaction><Myelencephalon><NHLBI><National Heart, Lung, and Blood Institute><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Nucleus Tractus Solitarii><Nucleus fastigii><Nucleus solitarius><O element><O2 element><Olives><Olives - dietary><Outcome><Oxygen><Oxygen Deficiency><Pathology><Physiopathology><Predisposition><Prevention><Process><Pulmonary Diseases><Pulmonary Disorder><Purkinje Cells><Purkinje's Corpuscles><Rat><Rats Mammals><Rattus><Receptor Protein><Receptor Signaling><Recovery><Research><Research Support><Risk Factors><Rodent><Rodentia><Rodents Mammals><Role><Running><SIDS><Safe Sleep><Safe to Sleep Campaign><Serotonergic System><Serotonin><Serotonin 2A Receptor><Serotonin 5-HT-2 Receptor Gene><Serotonin 5-HT-2A Receptor><Serotonin Receptor 5-HT2A><Solitary Nucleus><Source><Sudden Death><Sudden Infant Death><Sudden Unexpected Infant Death><Sudden infant death syndrome><Susceptibility><System><Testing><Time><Tissues><Trees><bacteriophage P1 recombinase Cre><bio-markers><biologic><biologic marker><biomarker><blood disorder><blood pressure homeostasis><blood pressure regulation><cardiovascular collapse><cardiovascular function><causation><cerebellar Purkinje cell><circulatory system><compare to control><comparison control><critical period><death among infants><death in first year of life><death in infancy><death in infants><designer receptors exclusively activated by designer drugs><developmental><disease causation><disease of the lung><disorder of the lung><environmental risk><evidence base><experience><experiment><experimental research><experimental study><experiments><fastigial nucleus><fiber cell><heart disorder><infant animal><infant death><infant demise><infantile death><injuries><innovate><innovation><innovative><lung disorder><model of animal><mortality in infants><necrocytosis><neonatal period><neural control><neural regulation><neuromodulation><neuromodulatory><neuronal><neuroregulation><novel><pathophysiology><pharmacologic><post-natal development><post-natal intermittent hypoxia><postnatal><postnatal development><prenatal><prevent><preventing><prophylactic><pup><receptor><receptor binding><receptor bound><receptor expression><regulate BP><regulate blood pressure><response><serotonergic pathway><serotonin pathway><serotonin receptor><serotonin system><social role><solitary tract nucleus><translational opportunities><translational potential><unborn>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

James C. Leiter

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$664,632

FY 2026

Project Title

SIDS, failed autoresuscitation, and a novel serotonergic brainstem-cerebellar circuit

Grant Number:

5R01HL179313-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The Sudden Infant Death Syndrome (SIDS) remains the leading cause of death in the post-neonatal period. Rare traces from infants who died of SIDS indicate cardiovascular collapse during autoresuscitation, the integrated cardiovascular and sympathetic response necessary to sustain life in severely hy...

Research Terms

<5-HT><5-HT Receptors><5-HT pathway><5-HT system><5-HT(2A) Receptor><5-HT-2A Gene><5-HT2A><5-HT2A Receptor><5-Hydroxytryptamine><5-Hydroxytryptamine (Serotonin) Receptor 2A Gene><5-Hydroxytryptamine Receptor 2A><5-Hydroxytryptamine Receptor 2A Gene><5-Hydroxytryptamine Receptors><5HT><Adoption><Affect><Animal Model><Animal Models and Related Studies><BP homeostasis><BP regulation><Back to Sleep><Binding><Biological><Biological Markers><Blood Diseases><Blood Pressure><Body Tissues><Brain><Brain Nervous System><Brain Stem><Brainstem><CRE Recombinase><Cardiac Chronotropism><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Causality><Cause of Death><Cell Body><Cell Death><Cells><Cerebellar Cortex><Cerebellum><Cessation of life><Clinical><Common Rat Strains><Cot Death><Crib Death><DREADDs><Death><Defect><Development><Dysfunction><Encephalon><Enteramine><Enterobacteria phage P1 Cre recombinase><Environmental Factor><Environmental Risk Factor><Etiology><Exposure to><Fiber><Functional disorder><HTR2><HTR2 Gene><HTR2A><HTR2A gene><Health><Heart Diseases><Heart Rate><Heart Vascular><Hematologic Diseases><Hematological Disease><Hematological Disorder><Hippophaine><Human><Hypoxia><Hypoxic><Impairment><Incidence><Individual><Infant><Infant Mortality><Infant Mortality Total><Injury><Knowledge><Life><Lung Diseases><Medial><Mediating><Medulla Oblongata><Mission><Modern Man><Molecular Interaction><Myelencephalon><NHLBI><National Heart, Lung, and Blood Institute><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Nucleus Tractus Solitarii><Nucleus fastigii><Nucleus solitarius><O element><O2 element><Olives><Olives - dietary><Outcome><Oxygen><Oxygen Deficiency><Pathology><Physiopathology><Predisposition><Prevention><Process><Pulmonary Diseases><Pulmonary Disorder><Purkinje Cells><Purkinje's Corpuscles><Rat><Rats Mammals><Rattus><Receptor Protein><Receptor Signaling><Recovery><Research><Research Support><Risk Factors><Rodent><Rodentia><Rodents Mammals><Role><Running><SIDS><Safe Sleep><Safe to Sleep Campaign><Serotonergic System><Serotonin><Serotonin 2A Receptor><Serotonin 5-HT-2 Receptor Gene><Serotonin 5-HT-2A Receptor><Serotonin Receptor 5-HT2A><Solitary Nucleus><Source><Sudden Death><Sudden Infant Death><Sudden Unexpected Infant Death><Sudden infant death syndrome><Susceptibility><System><Testing><Time><Tissues><Trees><bacteriophage P1 recombinase Cre><bio-markers><biologic><biologic marker><biomarker><blood disorder><blood pressure homeostasis><blood pressure regulation><cardiovascular collapse><cardiovascular function><causation><cerebellar Purkinje cell><circulatory system><compare to control><comparison control><critical period><death among infants><death in first year of life><death in infancy><death in infants><designer receptors exclusively activated by designer drugs><developmental><disease causation><disease of the lung><disorder of the lung><environmental risk><evidence base><experience><experiment><experimental research><experimental study><experiments><fastigial nucleus><fiber cell><heart disorder><infant animal><infant death><infant demise><infantile death><injuries><innovate><innovation><innovative><lung disorder><model of animal><mortality in infants><necrocytosis><neonatal period><neural control><neural regulation><neuromodulation><neuromodulatory><neuronal><neuroregulation><novel><pathophysiology><pharmacologic><post-natal development><post-natal intermittent hypoxia><postnatal><postnatal development><prenatal><prevent><preventing><prophylactic><pup><receptor><receptor binding><receptor bound><receptor expression><regulate BP><regulate blood pressure><response><serotonergic pathway><serotonin pathway><serotonin receptor><serotonin system><social role><solitary tract nucleus><translational opportunities><translational potential><unborn>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Katherine Teresa Mills

TULANE UNIVERSITY OF LOUISIANA, NEW ORLEANS, LA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$662,141

FY 2026

Project Title

A Mechanistic Trial of Dietary Sodium Reduction on Vascular Structure and Function in African Americans

Grant Number:

5R01HL155559-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/17/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary High dietary sodium intake increases risk of cardiovascular disease (CVD) independent of established risk factors, including blood pressure (BP). Non-BP mediated mechanisms underlying the increased risk of CVD associated with dietary sodium intake are not well understood, but observa...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Denice Hodgson-Zingman

UNIVERSITY OF IOWA, IOWA CITY, IA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$656,730

FY 2026

Project Title

A New Pacing Approach for Cardiac Conditioning and Enhanced Cardioprotection

Grant Number:

5R01HL168752-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Significant advances in prevention and mitigation of cardiovascular disease have been made, but related morbidity and mortality remain high. Cardiac conditioning is a therapeutic approach to induce endogenous protective adaptive responses in the heart for counteracting myocardial loss. Identificatio...

Research Terms

<21+ years old><Acceleration><Adult><Adult Human><Adverse effects><Age><Approaches to prevention><Atrial><Automobile Driving><Back><Biochemical><CREB><CREB1><CREB1 gene><Cardiac><Cardiac Atrium><Cardiac Chronotropism><Cardiac Diseases><Cardiac Disorders><Cardiac rehabilitation><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Causality><Chronic><Clinical><Complement><Complement Proteins><Coupled><Data><Deceleration><Devices><Disease><Disorder><Dissociation><Dorsum><Dysfunction><EFRAC><Ejection Fraction><Elements><Etiology><Evaluation><Event><Exercise><Exercise Tolerance><Expression Signature><Functional disorder><Gene Expression Profile><Gene Transcription><Genetic><Genetic Transcription><Heart><Heart Atrium><Heart Diseases><Heart Injuries><Heart Rate><Heart Vascular><Heart failure><Human><Impairment><Implant><Injury><Intervention><Ischemia><Ischemic Heart><Ischemic Heart Disease><Ischemic Preconditioning><Ischemic myocardium><KO mice><Knock-out Mice><Knockout Mice><LVEF><Left Ventricular Dysfunction><Left Ventricular Ejection Fraction><Link><Lipids><Manuals><Medical><Metabolic><Methods><Mice><Mice Mammals><Mitochondria><Modern Man><Molecular><Morbidity><Murine><Mus><Myocardial><Myocardial Diseases><Myocardial Disorder><Myocardial Ischemia><Myocardiopathies><NIH><National Institutes of Health><Network Analysis><Null Mouse><Optic atrophy 1><Outcome><PPAR gamma><PPAR-g><PPAR-γ><PPARgamma><PPARγ><Pathway Analysis><Patients><Pattern><Peroxisome Proliferative Activated Receptor Gamma><Peroxisome Proliferator-Activated Receptor gamma><Peroxisome Proliferator-Activated Receptor γ><Persons><Phase 2 Clinical Trials><Phase II Clinical Trials><Physical activity><Physiopathology><Prevention><Prevention approach><Proteins><Protocol><Protocols documentation><Publishing><QOL><Quality of life><RNA Expression><Randomized><Receptor Protein><Recommendation><Refractory><Regulation><Resistance><Rest><Risk><Risk Reduction><Role><Safety><Signal Pathway><Stress><Systolic heart failure><Testing><Therapeutic><Thiazolidinedione Receptor><Transcription><United States National Institutes of Health><Upregulation><Walking><adrenergic stress><adulthood><ages><cAMP Response Element-Binding Protein 1><cardiac failure><cardiac injury><cardiac ischemia><cardiac pacing><cardiac rehab><cardioprotectant><cardioprotection><cardioprotective><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><causation><circulatory system><clinical relevance><clinically relevant><complementation><conditioning><coronary ischemia><disease causation><driving><exercise intolerance><falls><functional status><gene expression pattern><gene expression signature><heart disorder><heart ischemia><heart rehabilitation><hemodynamics><human subject><improved><improved outcome><in vivo><injuries><injury to the myocardium><insight><left ventricle abnormality><mitochondrial><mortality><mouse model><murine model><myocardial injury><myocardial ischemia/hypoxia><myocardium disease><myocardium disorder><myocardium ischemia><new approaches><novel><novel approaches><novel strategies><novel strategy><pathophysiology><phase II protocol><physical conditioning><physical health><pilot test><preservation><prevent><preventing><programs><randomisation><randomization><randomly assigned><receptor><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><resistant><response><risk-reducing><social role><stress tolerance><transcriptional profile><transcriptional signature><treadmill><treadmill training><trend>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Leonid Zingman

UNIVERSITY OF IOWA, IOWA CITY, IA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$656,730

FY 2026

Project Title

A New Pacing Approach for Cardiac Conditioning and Enhanced Cardioprotection

Grant Number:

5R01HL168752-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Significant advances in prevention and mitigation of cardiovascular disease have been made, but related morbidity and mortality remain high. Cardiac conditioning is a therapeutic approach to induce endogenous protective adaptive responses in the heart for counteracting myocardial loss. Identificatio...

Research Terms

<21+ years old><Acceleration><Adult><Adult Human><Adverse effects><Age><Approaches to prevention><Atrial><Automobile Driving><Back><Biochemical><CREB><CREB1><CREB1 gene><Cardiac><Cardiac Atrium><Cardiac Chronotropism><Cardiac Diseases><Cardiac Disorders><Cardiac rehabilitation><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Causality><Chronic><Clinical><Complement><Complement Proteins><Coupled><Data><Deceleration><Devices><Disease><Disorder><Dissociation><Dorsum><Dysfunction><EFRAC><Ejection Fraction><Elements><Etiology><Evaluation><Event><Exercise><Exercise Tolerance><Expression Signature><Functional disorder><Gene Expression Profile><Gene Transcription><Genetic><Genetic Transcription><Heart><Heart Atrium><Heart Diseases><Heart Injuries><Heart Rate><Heart Vascular><Heart failure><Human><Impairment><Implant><Injury><Intervention><Ischemia><Ischemic Heart><Ischemic Heart Disease><Ischemic Preconditioning><Ischemic myocardium><KO mice><Knock-out Mice><Knockout Mice><LVEF><Left Ventricular Dysfunction><Left Ventricular Ejection Fraction><Link><Lipids><Manuals><Medical><Metabolic><Methods><Mice><Mice Mammals><Mitochondria><Modern Man><Molecular><Morbidity><Murine><Mus><Myocardial><Myocardial Diseases><Myocardial Disorder><Myocardial Ischemia><Myocardiopathies><NIH><National Institutes of Health><Network Analysis><Null Mouse><Optic atrophy 1><Outcome><PPAR gamma><PPAR-g><PPAR-γ><PPARgamma><PPARγ><Pathway Analysis><Patients><Pattern><Peroxisome Proliferative Activated Receptor Gamma><Peroxisome Proliferator-Activated Receptor gamma><Peroxisome Proliferator-Activated Receptor γ><Persons><Phase 2 Clinical Trials><Phase II Clinical Trials><Physical activity><Physiopathology><Prevention><Prevention approach><Proteins><Protocol><Protocols documentation><Publishing><QOL><Quality of life><RNA Expression><Randomized><Receptor Protein><Recommendation><Refractory><Regulation><Resistance><Rest><Risk><Risk Reduction><Role><Safety><Signal Pathway><Stress><Systolic heart failure><Testing><Therapeutic><Thiazolidinedione Receptor><Transcription><United States National Institutes of Health><Upregulation><Walking><adrenergic stress><adulthood><ages><cAMP Response Element-Binding Protein 1><cardiac failure><cardiac injury><cardiac ischemia><cardiac pacing><cardiac rehab><cardioprotectant><cardioprotection><cardioprotective><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><causation><circulatory system><clinical relevance><clinically relevant><complementation><conditioning><coronary ischemia><disease causation><driving><exercise intolerance><falls><functional status><gene expression pattern><gene expression signature><heart disorder><heart ischemia><heart rehabilitation><hemodynamics><human subject><improved><improved outcome><in vivo><injuries><injury to the myocardium><insight><left ventricle abnormality><mitochondrial><mortality><mouse model><murine model><myocardial injury><myocardial ischemia/hypoxia><myocardium disease><myocardium disorder><myocardium ischemia><new approaches><novel><novel approaches><novel strategies><novel strategy><pathophysiology><phase II protocol><physical conditioning><physical health><pilot test><preservation><prevent><preventing><programs><randomisation><randomization><randomly assigned><receptor><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><resistant><response><risk-reducing><social role><stress tolerance><transcriptional profile><transcriptional signature><treadmill><treadmill training><trend>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alden L. Gross

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$655,139

FY 2026

Project Title

Socioeconomic, Cardiovascular, and Psychosocial Sources of Cross-National Variation in Cognitive Health Among Older Adults

Grant Number:

2R01AG070953-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2021

End Date:

3/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The NIA-funded Harmonized Cognitive Assessment Protocols (HCAPs) are a major innovation to facilitate valid cross-national comparisons of Alzheimer’s disease and related dementias (ADRD). The methodology supporting such cross-national comparisons is continually evolving. Our original...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lindsay C Kobayashi

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$655,139

FY 2026

Project Title

Socioeconomic, Cardiovascular, and Psychosocial Sources of Cross-National Variation in Cognitive Health Among Older Adults

Grant Number:

2R01AG070953-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2021

End Date:

3/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The NIA-funded Harmonized Cognitive Assessment Protocols (HCAPs) are a major innovation to facilitate valid cross-national comparisons of Alzheimer’s disease and related dementias (ADRD). The methodology supporting such cross-national comparisons is continually evolving. Our original...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rebekah J Walker

STATE UNIVERSITY OF NEW YORK AT BUFFALO, AMHERST, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$653,051

FY 2026

Project Title

Cardiovascular Risk Reduction for Adults with Food Insecurity Using Structured Incentives (CVD-FIT)

Grant Number:

5R01MD018721-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Cardiovascular disease (CVD) is associated with significant morbidity and mortality, decreased quality of life, and increased health care utilization and cost. Food insecurity, defined as limited or uncertain access to adequate food for an active, healthy life, is reported by nearly one third of adu...

Research Terms

<21+ years old><Address><Adult><Adult Human><African American><African American group><African American individual><African American people><African American population><African Americans><Afro American><Afroamerican><Age><Area><Behavior><Blood Pressure><Cardiovascular Diseases><Cessation of life><Chronic><Communities><Data><Death><Diabetes Mellitus><Diet><Disease Outcome><Economics><Education><Education and Training><Educational aspects><Equation><Food><Food Access><Food Supplementation><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Utilization><Health Food><Health behavior><Healthy Eating><Hemoglobin A(1)><Home><Impoverished><Incentives><Individual><Intervention><Life><Lipids><Measures><Mediator><Mental Health><Mental Hygiene><Morbidity><Nutritious food><Outcome><Participant><Patients><Persons><Pilot Projects><Population><Poverty><Psychological Health><QOL><QOL improvement><Quality of life><Randomized><Reporting><Research><Research Resources><Resources><Risk><Risk Factors><Risk Reduction><Socio-economic status><Socioeconomic Status><Structure><Study Section><Supermarket><Testing><Training and Education><US Department of Agriculture><USDA><United States><United States Department of Agriculture><adulthood><aged><ages><behavior change><behavioral economics><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><care as usual><care costs><cohort><cost effective><cost effectiveness><death risk><delivered via telephone><diabetes><dietary><diets><economic><efficacy testing><ethnic minority><evidence base><experience><farmers markets><food insecure><food insecurity><food scarcity><health care service use><health care service utilization><health related behavior><healthy food><hemoglobin A1c><homes><improved><improved outcome><improvements in QOL><improvements in quality of life><indexing><intervention effect><low food security><mortality><mortality risk><motivated behavior><multi-component intervention><multi-faceted intervention><multi-modal intervention><multicomponent intervention><multifaceted intervention><multimodal intervention><novel><perceived stress><perception of stress><physical conditioning><physical health><pilot study><primary outcome><program costs><quality of life improvement><randomisation><randomization><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><self-reported stress><sex><skills training><socio-economic position><socioeconomic position><stress perception><telephone based delivery><telephone delivered><telephone delivery><treatment as usual><usual care><voucher>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Orlando M Gutierrez

TUFTS MEDICAL CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$626,483

FY 2026

Project Title

Dimensions of Kidney Tubule Health and Atherosclerotic Cardiovascular Disease and Heart Failure in Middle-Aged and Older Adults

Grant Number:

5R01HL167233-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/25/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Two clinical measures are currently used to stage chronic kidney disease (CKD), the estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (ACR). The elevated morbidity and mortality risk that is experienced by persons with CKD is overwhelmingly a result of progr...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joachim H Ix

TUFTS MEDICAL CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$626,483

FY 2026

Project Title

Dimensions of Kidney Tubule Health and Atherosclerotic Cardiovascular Disease and Heart Failure in Middle-Aged and Older Adults

Grant Number:

5R01HL167233-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/25/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Two clinical measures are currently used to stage chronic kidney disease (CKD), the estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (ACR). The elevated morbidity and mortality risk that is experienced by persons with CKD is overwhelmingly a result of progr...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARK J SARNAK

TUFTS MEDICAL CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$626,483

FY 2026

Project Title

Dimensions of Kidney Tubule Health and Atherosclerotic Cardiovascular Disease and Heart Failure in Middle-Aged and Older Adults

Grant Number:

5R01HL167233-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/25/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Two clinical measures are currently used to stage chronic kidney disease (CKD), the estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (ACR). The elevated morbidity and mortality risk that is experienced by persons with CKD is overwhelmingly a result of progr...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael G Shlipak

TUFTS MEDICAL CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$626,483

FY 2026

Project Title

Dimensions of Kidney Tubule Health and Atherosclerotic Cardiovascular Disease and Heart Failure in Middle-Aged and Older Adults

Grant Number:

5R01HL167233-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/25/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Two clinical measures are currently used to stage chronic kidney disease (CKD), the estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (ACR). The elevated morbidity and mortality risk that is experienced by persons with CKD is overwhelmingly a result of progr...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bethany Barone Gibbs

UNIVERSITY OF IOWA, IOWA CITY, IA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$623,719

FY 2026

Project Title

Sedentary behavior, physical activity, and 24-hour behavior in pregnancy and offspring health: the Pregnancy 24/7 Offspring Study

Grant Number:

5R01HL164662-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/17/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Over the past three decades, there has been an alarming increase in the incidence of childhood obesity. Childhood obesity leads to early onset of cardiovascular risk factors, and both obesity and cardiovascular risk factors track into adulthood and contribute to the epidemic of cardiovascul...

Research Terms

<0-11 years old><1st trimester><21+ years old><Address><Adult><Adult Human><BMI><BMI percentile><BMI z-score><Behavior><Behavior assessment><Birth><Blood Pressure><Body mass index><Breast Feeding><Cardiovascular Diseases><Cause of Death><Child><Child Health><Child Youth><Childhood><Children (0-21)><Cohort Studies><Data><Data Analyses><Data Analysis><Development><Diet><Disease><Disorder><Early Placental Phase><Enrollment><Epidemic><Fetal Growth><First Pregnancy Trimester><First Trimester><Future><Generalized Growth><Gestation><Goals><Growth><Health><Home environment><Hour><Hypertension><Incidence><Intervention><Late pregnancy><Link><Maternal Behavior><Maternal Exposure><Maternal Health><Measurement><Measures><Medical Records><Methods><Modeling><Monitor><NHLBI><National Heart, Lung, and Blood Institute><Obesity><Outcome><Participant><Parturition><Pattern><Persons><Physical activity><Physiologic><Physiologic pulse><Physiological><Pregnancy><Pregnancy Trimesters><Pregnant Women><Preventative intervention><Prevention><Primary Prevention><Pulse><Questionnaires><Quetelet index><Research><Risk><Risk Factors><Risk Reduction><Role><Sedentary behavior><Sedentary life-style><Site><Sleep><Smoking><Statistical Methods><Time><Tissue Growth><Unhealthy Diet><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular aging><Visit><Woman><adiposity><adulthood><adverse pregnancy outcome><after pregnancy><behavioral assessment><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical relevance><clinically relevant><cohort research study><cohort survey><corpulence><data interpretation><developmental><diets><early childhood><early onset><enroll><expectant mother><expectant women><expecting mother><expecting women><exposed in utero><fetal exposure><fetal programming><gestational weight gain><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><in utero><in utero exposure><individuals who are pregnant><interest><intervention for prevention><intra-uterine environmental exposure><intra-uterine growth><intrauterine environmental exposure><intrauterine growth><kids><later in life><later life><life span><lifespan><modifiable behavior><novel><obese children><obesity during childhood><obesity in children><obesity risk><observational cohort study><offspring><offspring obesity><ontogeny><pediatric><pediatric obesity><people who are pregnant><poor diet><poor sleep><post pregnancy><postnatal><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prenatal exposure><prenatally exposed><prepregnancy obesity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary outcome><prospective><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><sedentary lifestyle><social role><statistic methods><theories><those who are pregnant><unborn><vasculature aging><vigorous intensity><women who are pregnant><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kara Marie Whitaker

UNIVERSITY OF IOWA, IOWA CITY, IA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$623,719

FY 2026

Project Title

Sedentary behavior, physical activity, and 24-hour behavior in pregnancy and offspring health: the Pregnancy 24/7 Offspring Study

Grant Number:

5R01HL164662-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/17/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Over the past three decades, there has been an alarming increase in the incidence of childhood obesity. Childhood obesity leads to early onset of cardiovascular risk factors, and both obesity and cardiovascular risk factors track into adulthood and contribute to the epidemic of cardiovascul...

Research Terms

<0-11 years old><1st trimester><21+ years old><Address><Adult><Adult Human><BMI><BMI percentile><BMI z-score><Behavior><Behavior assessment><Birth><Blood Pressure><Body mass index><Breast Feeding><Cardiovascular Diseases><Cause of Death><Child><Child Health><Child Youth><Childhood><Children (0-21)><Cohort Studies><Data><Data Analyses><Data Analysis><Development><Diet><Disease><Disorder><Early Placental Phase><Enrollment><Epidemic><Fetal Growth><First Pregnancy Trimester><First Trimester><Future><Generalized Growth><Gestation><Goals><Growth><Health><Home environment><Hour><Hypertension><Incidence><Intervention><Late pregnancy><Link><Maternal Behavior><Maternal Exposure><Maternal Health><Measurement><Measures><Medical Records><Methods><Modeling><Monitor><NHLBI><National Heart, Lung, and Blood Institute><Obesity><Outcome><Participant><Parturition><Pattern><Persons><Physical activity><Physiologic><Physiologic pulse><Physiological><Pregnancy><Pregnancy Trimesters><Pregnant Women><Preventative intervention><Prevention><Primary Prevention><Pulse><Questionnaires><Quetelet index><Research><Risk><Risk Factors><Risk Reduction><Role><Sedentary behavior><Sedentary life-style><Site><Sleep><Smoking><Statistical Methods><Time><Tissue Growth><Unhealthy Diet><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular aging><Visit><Woman><adiposity><adulthood><adverse pregnancy outcome><after pregnancy><behavioral assessment><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical relevance><clinically relevant><cohort research study><cohort survey><corpulence><data interpretation><developmental><diets><early childhood><early onset><enroll><expectant mother><expectant women><expecting mother><expecting women><exposed in utero><fetal exposure><fetal programming><gestational weight gain><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><in utero><in utero exposure><individuals who are pregnant><interest><intervention for prevention><intra-uterine environmental exposure><intra-uterine growth><intrauterine environmental exposure><intrauterine growth><kids><later in life><later life><life span><lifespan><modifiable behavior><novel><obese children><obesity during childhood><obesity in children><obesity risk><observational cohort study><offspring><offspring obesity><ontogeny><pediatric><pediatric obesity><people who are pregnant><poor diet><poor sleep><post pregnancy><postnatal><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prenatal exposure><prenatally exposed><prepregnancy obesity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary outcome><prospective><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><sedentary lifestyle><social role><statistic methods><theories><those who are pregnant><unborn><vasculature aging><vigorous intensity><women who are pregnant><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Petra Simic

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$622,959

FY 2026

Project Title

GPAT2 REGULATES MINERAL METABOLISM IN KIDNEY DISEASE

Grant Number:

1R01DK146964-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT: GPAT2 REGULATES MINERAL METABOLISM IN KIDNEY DISEASE Mineral disorder is a common complication of chronic kidney disease and is characterized by increased vascular mineralization and impaired skeletal mineralization—a phenomenon known as the mineralization paradox. This imbalance contribut...

Research Terms

<1-phosphoglycerol><Acyltransferase><Address><Age><Aging><Blood Plasma><Blood Serum><Blood Vessels><Body Tissues><Bone Diseases><Bone Formation><Bone Matrix><Bone Mineralization><Cardiac><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Complication><Data><Defect><Development><Diet><Disease><Disorder><Dissociation><EC 2.3><Endocrine Gland Secretion><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Equilibrium><Esterified Fatty Acids><Excretory function><Exhibits><FGF23 gene product><Fats><Fatty Acid Metabolism Pathway><Fatty acid glycerol esters><Free Fatty Acids><Genetic><Goals><Heart><Heart Hypertrophy><Heart Vascular><Hormones><Impairment><In Vitro><Injury to Kidney><Intermediary Metabolism><Intracellular Communication and Signaling><Kidney><Kidney Diseases><Kidney Urinary System><Knock-out><Knockout><Lamellar Bone><Lipids><MOPA><Mature Bone><Metabolic><Metabolic Pathway><Metabolic Processes><Metabolism><Mice><Mice Mammals><Minerals><Morbidity><Morphology><Murine><Mus><Myocardial Diseases><Myocardial Disorder><Myocardiopathies><Nephropathy><Nonesterified Fatty Acids><Osteoblasts><Osteogenesis><Outcome><Pathologic><Patients><Peripheral><Persons><Phosphates><Physiologic calcification><Plasma><Plasma Serum><Production><Renal Disease><Renal Tissue><Renal clearance function><Renal function><Research Support><Reticuloendothelial System, Serum, Plasma><Risk><Role><Serum><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Site><Stress><Testing><Tet><Tetanus Helper Peptide><Therapeutic Hormone><Tissues><Triacylglycerol><Triglycerides><Vascular calcification><adverse consequence><adverse outcome><ages><alpha-glycerophosphate><alpha-glycerophosphoric acid><balance><balance function><biological signal transduction><bone><bone cell><bone disorder><bone health><bone quality><bone tissue formation><bone turnover><cardiac hypertrophy><cardiovascular disorder><cardiovascular health><cardiovascular risk><cardiovascular risk factor><chronic kidney disease><circulatory system><design><designing><developmental><diets><disease model><disorder model><drug discovery><effective therapy><effective treatment><excretion><fat metabolism><fatty acid metabolism><fatty acid oxidation><fibroblast growth factor 23><fracture risk><glycerol 1-phosphate><glycerol 3-phosphate><improved><improved outcome><in vivo><inhibitor><inorganic phosphate><insight><kidney disorder><kidney function><kidney injury><lipid metabolism><lysophosphatidic acid><mineralization><monooleylphosphatidate><monooleylphosphatidic acid><mortality><mouse model><murine model><myocardium disease><myocardium disorder><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><osteoblast cell differentiation><osteoblast differentiation><osteoblastic differentiation><oxidation><pharmacologic><prevent><preventing><renal><renal clearance><renal disorder><renal injury><skeletal><skeletal disease><skeletal disorder><social role><soft tissue><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PAUL STEFAN DE VRIES

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$616,029

FY 2026

Project Title

The Role of Arylsulfatase in Vascular Calcification

Grant Number:

5R01HL162928-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Vascular calcification is a hallmark of atherosclerotic cardiovascular diseases such as myocardial infarction and stroke, which are the leading causes of morbidity and mortality in the world. Although coronary artery calcification (CAC) is a strong independent risk factor for cardiov...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rajeev Malhotra

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$616,029

FY 2026

Project Title

The Role of Arylsulfatase in Vascular Calcification

Grant Number:

5R01HL162928-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Vascular calcification is a hallmark of atherosclerotic cardiovascular diseases such as myocardial infarction and stroke, which are the leading causes of morbidity and mortality in the world. Although coronary artery calcification (CAC) is a strong independent risk factor for cardiov...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Camila Margarita Manrique Acevedo

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$603,556

FY 2026

Project Title

SGLT2 inhibition as a therapeutic strategy to reverse arterial stiffening in aging

Grant Number:

5R01AG082413-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Cardiovascular disease (CVD) is the main cause of death in older adults in the US and the burden of aging- associated CVD is expected to grow as the percentage of the older population steadily grows. A key characteristic of vascular aging is arterial stiffening, which is a c...

Research Terms

<ATP-protein phosphotransferase><Actin Filaments><Actins><Address><Age Years><Aging><Arteries><Blood Vessels><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Cell-Extracellular Matrix><Characteristics><Clinical Trials><Co-Transporters><Collagen><D-Glucose><Dephosphorylation><Deposit><Deposition><Development><Dextrose><Diabetes Mellitus><Down-Regulation><Drugs><ECM><Event><Extracellular Matrix><F-Actin><Family member><Female><Filamentous Actin><GeneHomolog><Glucose><Goals><Heart Vascular><Heart failure><Homolog><Homologous Gene><Homologue><Kidney><Kidney Urinary System><Kinase Family Gene><Knowledge><LIM Domain Kinase 1><LIM kinase><LIMK protein><LIMK-1><Leiomyocyte><Mediating><Medication><Microfilaments><Molecular><Monomeric G-Proteins><Monomeric GTP-Binding Proteins><Morbidity><Myofilaments><Na element><Older Population><Pathogenesis><Pathway interactions><Patients><Pharmaceutical Preparations><Phosphorylation><Polymers><Protein Dephosphorylation><Protein Kinase><Protein Phosphorylation><Publishing><Reducing Agents><Reductants><Research><Role><SGLT 2 inhibitor><SGLT2i><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Sodium><Sodium glucose co-transporter 2 inhibitor><Stress Fibers><Testing><Therapeutic><Time><Vascular Smooth Muscle><Vascular aging><Vascular remodeling><age reversal><aging associated><aging related><aging reversal><alleviate age related><alleviate aging><ameliorating aging><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><cardiac failure><cardiovascular disorder><cardiovascular effects><circulatory system><cofilin><cohort><counter age related><counter aging><counteract age related><counteract aging><depolymerization><design><designing><determine efficacy><developmental><diabetes><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><evaluate efficacy><examine efficacy><experiment><experimental research><experimental study><experiments><gain of function><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><glycogen synthase a kinase><hydroxyalkyl protein kinase><in vivo><loss of function><male><mortality><mouse model><murine model><older adult><older adulthood><older groups><older individuals><older person><pathway><pharmacologic><phosphorylase b kinase kinase><polymer><polymeric><polymerization><prevent><preventing><randomized placebo-controlled clinical trial><renal><reverse age><reverse aging><reverse aging effects><reversible aging><rho><social role><symporter><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic target><vascular><vasculature aging><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Luis A Martinez-Lemus

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$603,556

FY 2026

Project Title

SGLT2 inhibition as a therapeutic strategy to reverse arterial stiffening in aging

Grant Number:

5R01AG082413-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Cardiovascular disease (CVD) is the main cause of death in older adults in the US and the burden of aging- associated CVD is expected to grow as the percentage of the older population steadily grows. A key characteristic of vascular aging is arterial stiffening, which is a c...

Research Terms

<ATP-protein phosphotransferase><Actin Filaments><Actins><Address><Age Years><Aging><Arteries><Blood Vessels><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Cell-Extracellular Matrix><Characteristics><Clinical Trials><Co-Transporters><Collagen><D-Glucose><Dephosphorylation><Deposit><Deposition><Development><Dextrose><Diabetes Mellitus><Down-Regulation><Drugs><ECM><Event><Extracellular Matrix><F-Actin><Family member><Female><Filamentous Actin><GeneHomolog><Glucose><Goals><Heart Vascular><Heart failure><Homolog><Homologous Gene><Homologue><Kidney><Kidney Urinary System><Kinase Family Gene><Knowledge><LIM Domain Kinase 1><LIM kinase><LIMK protein><LIMK-1><Leiomyocyte><Mediating><Medication><Microfilaments><Molecular><Monomeric G-Proteins><Monomeric GTP-Binding Proteins><Morbidity><Myofilaments><Na element><Older Population><Pathogenesis><Pathway interactions><Patients><Pharmaceutical Preparations><Phosphorylation><Polymers><Protein Dephosphorylation><Protein Kinase><Protein Phosphorylation><Publishing><Reducing Agents><Reductants><Research><Role><SGLT 2 inhibitor><SGLT2i><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Sodium><Sodium glucose co-transporter 2 inhibitor><Stress Fibers><Testing><Therapeutic><Time><Vascular Smooth Muscle><Vascular aging><Vascular remodeling><age reversal><aging associated><aging related><aging reversal><alleviate age related><alleviate aging><ameliorating aging><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><cardiac failure><cardiovascular disorder><cardiovascular effects><circulatory system><cofilin><cohort><counter age related><counter aging><counteract age related><counteract aging><depolymerization><design><designing><determine efficacy><developmental><diabetes><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><evaluate efficacy><examine efficacy><experiment><experimental research><experimental study><experiments><gain of function><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><glycogen synthase a kinase><hydroxyalkyl protein kinase><in vivo><loss of function><male><mortality><mouse model><murine model><older adult><older adulthood><older groups><older individuals><older person><pathway><pharmacologic><phosphorylase b kinase kinase><polymer><polymeric><polymerization><prevent><preventing><randomized placebo-controlled clinical trial><renal><reverse age><reverse aging><reverse aging effects><reversible aging><rho><social role><symporter><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic target><vascular><vasculature aging><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jaume Padilla

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$603,556

FY 2026

Project Title

SGLT2 inhibition as a therapeutic strategy to reverse arterial stiffening in aging

Grant Number:

5R01AG082413-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Cardiovascular disease (CVD) is the main cause of death in older adults in the US and the burden of aging- associated CVD is expected to grow as the percentage of the older population steadily grows. A key characteristic of vascular aging is arterial stiffening, which is a c...

Research Terms

<ATP-protein phosphotransferase><Actin Filaments><Actins><Address><Age Years><Aging><Arteries><Blood Vessels><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Cell-Extracellular Matrix><Characteristics><Clinical Trials><Co-Transporters><Collagen><D-Glucose><Dephosphorylation><Deposit><Deposition><Development><Dextrose><Diabetes Mellitus><Down-Regulation><Drugs><ECM><Event><Extracellular Matrix><F-Actin><Family member><Female><Filamentous Actin><GeneHomolog><Glucose><Goals><Heart Vascular><Heart failure><Homolog><Homologous Gene><Homologue><Kidney><Kidney Urinary System><Kinase Family Gene><Knowledge><LIM Domain Kinase 1><LIM kinase><LIMK protein><LIMK-1><Leiomyocyte><Mediating><Medication><Microfilaments><Molecular><Monomeric G-Proteins><Monomeric GTP-Binding Proteins><Morbidity><Myofilaments><Na element><Older Population><Pathogenesis><Pathway interactions><Patients><Pharmaceutical Preparations><Phosphorylation><Polymers><Protein Dephosphorylation><Protein Kinase><Protein Phosphorylation><Publishing><Reducing Agents><Reductants><Research><Role><SGLT 2 inhibitor><SGLT2i><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Sodium><Sodium glucose co-transporter 2 inhibitor><Stress Fibers><Testing><Therapeutic><Time><Vascular Smooth Muscle><Vascular aging><Vascular remodeling><age reversal><aging associated><aging related><aging reversal><alleviate age related><alleviate aging><ameliorating aging><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><cardiac failure><cardiovascular disorder><cardiovascular effects><circulatory system><cofilin><cohort><counter age related><counter aging><counteract age related><counteract aging><depolymerization><design><designing><determine efficacy><developmental><diabetes><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><evaluate efficacy><examine efficacy><experiment><experimental research><experimental study><experiments><gain of function><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><glycogen synthase a kinase><hydroxyalkyl protein kinase><in vivo><loss of function><male><mortality><mouse model><murine model><older adult><older adulthood><older groups><older individuals><older person><pathway><pharmacologic><phosphorylase b kinase kinase><polymer><polymeric><polymerization><prevent><preventing><randomized placebo-controlled clinical trial><renal><reverse age><reverse aging><reverse aging effects><reversible aging><rho><social role><symporter><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic target><vascular><vasculature aging><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jonathan Ho-Youn Kim

EMORY UNIVERSITY, ATLANTA, GA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$597,542

FY 2026

Project Title

Obstructive Sleep Apnea and Associated Pathologic Cardiovascular Phenotypes in Young Individuals: A Comprehensive and Longitudinal Analysis of At-Risk College-Aged Students

Grant Number:

5R01HL162712-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Obstructive sleep apnea (OSA) is highly prevalent across the age spectrum and associated with significant cardiovascular (CV) diseases. To date, our understanding of the association between OSA and CV pathobiology comes from limited cross-sectional data examining older indi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Maria Argos

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$594,877

FY 2026

Project Title

Impact of Metals on Biological Aging and Cardiometabolic Traits in Adolescents

Grant Number:

5R01ES033883-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2022

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT The ubiquitous presence of toxic metal exposures in the environment is a global public health concern, with disadvantaged populations disproportionately exposed and susceptible to adverse effects. Lead, arsenic, cadmium, and mercury are the most commonly occurring toxic environmental metal ...

Research Terms

<11 year old><11 years of age><12-20 years old><21+ years old><Address><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Adverse effects><Affect><Age><Arsenic><BMI><BMI percentile><BMI z-score><Bangladesh><Biological Aging><Biometrics><Biometry><Biosensor><Biostatistics><Blood Pressure><Blood leukocyte><Body mass index><C-reactive protein><Cadmium><Cardiovascular Diseases><Cd element><Child Health><Childhood><Cholesterol><Clip><DNA><DNA Methylation><Data><Deoxyribonucleic Acid><Development><Disparity population><Dysfunction><Environment><Environmental Factor><Environmental Risk Factor><Epidemiologic Research><Frequencies><Functional disorder><Future><General Population><General Public><Goals><Health><Hg element><Humulin R><Individual><Insulin><Knowledge><Laboratories><Lead><Learning><Length><Leukocytes><Leukocytes Reticuloendothelial System><Life><Life Cycle><Life Cycle Stages><Literature><Marrow leukocyte><Measures><Mediation><Mercury><Metal exposure><Metals><Methods><Methylation><Negotiating><Negotiation><Novolin R><Outcome><Pathogenesis><Pb element><Phenotype><Physiopathology><Poison><Population Study><Predisposition><Proteins, specific or class, C-reactive><Public Health><Quetelet index><Regular Insulin><Research><Research Resources><Resources><Risk Reduction><Rural><Sampling><Site><Spottings><Structure of nail of toe><Susceptibility><Testing><Time><Toe Nail><Toenail><Toxic Chemical><Toxic Substance><Toxic effect><Toxicities><Urine><Visit><Vulnerable Populations><White Blood Cells><White Cell><Whole Blood><Youth><Youth 10-21><adolescence (12-20)><adulthood><age 11><age 11 years><ages><arsenics><biological process of age><biological sensor><cardiometabolic><cardiometabolic risk><cardiometabolism><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><co-exposures><co-occurring exposure><cohort><combined exposure><complex exposure><concurrent exposure><developmental><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disease prevention><disease registry><disorder prevention><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><eleven year old><eleven years of age><environmental risk><epidemiologic investigation><epigenome><exposed human population><exposure mixture><exposure to metal><fasting plasma glucose><group disparity><group inequality><group inequity><heavy metal Pb><heavy metal lead><high risk><human exposure><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><innovate><innovation><innovative><insight><investigate epidemiology><juvenile><juvenile human><later in life><later life><life course><mixed exposure><novel><participant enrollment><pathophysiology><patient enrollment><pediatric><population inequality><population inequity><population research study><population survey><population-based study><population-level study><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><remediation><risk-reducing><simultaneous exposures><study epidemiology><subgroup disparity><survey epidemiology><telomere><toxic compound><toxic metal><trait><unequal group><unequal population><vulnerable group><vulnerable individual><vulnerable people><white blood cell><white blood corpuscle><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michal Laniado Schwartzman

NEW YORK MEDICAL COLLEGE, VALHALLA, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$538,812

FY 2026

Project Title

GPR75 in obesity-driven cardiovascular and metabolic complications

Grant Number:

5R01HL168056-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Summary Obesity and the associated metabolic complications including metabolic syndrome and diabetes significantly contribute to cardiovascular morbidities. The overall goal of this proposal is aimed at identifying cellular mechanisms that link activation of the G-protein coupled receptor ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Laura B Attanasio

BAYSTATE MEDICAL CENTER, INC., SPRINGFIELD, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$534,998

FY 2026

Project Title

System factors influencing the postpartum transition to primary care for cardiovascular disease risk management among women with hypertensive disorders in pregnancy

Grant Number:

5R01HL164489-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Cardiovascular disease (CVD) is the leading cause of death among women in the United States. Women who experience hypertensive disorders in pregnancy (HDP), including chronic hypertension, gestational hypertension, and pre-eclampsia/eclampsia, face substantially higher future CVD ri...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kimberley Lynn H Geissler

BAYSTATE MEDICAL CENTER, INC., SPRINGFIELD, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$534,998

FY 2026

Project Title

System factors influencing the postpartum transition to primary care for cardiovascular disease risk management among women with hypertensive disorders in pregnancy

Grant Number:

5R01HL164489-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Cardiovascular disease (CVD) is the leading cause of death among women in the United States. Women who experience hypertensive disorders in pregnancy (HDP), including chronic hypertension, gestational hypertension, and pre-eclampsia/eclampsia, face substantially higher future CVD ri...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ZHENYU Li

TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, COLLEGE STATION, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$507,916

FY 2026

Project Title

BNP not just a biomarker of cardiovascular disease

Grant Number:

5R01HL167767-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract: Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are powerful vasodilators, which are secreted by heart muscle cells. BNP and N-terminal proBNP (NT-proBNP) are widely used as diagnostic biomarkers for heart failure (HF) and cardiac dysfunction in clinical medicine. Pla...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yuki Oka

CALIFORNIA INSTITUTE OF TECHNOLOGY, PASADENA, CA

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,851,240

FY 2026

Project Title

State-dependent Modulation of Salt Taste and Ingestion

Grant Number:

1R01DC023427-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY Maintaining sodium balance is critical for survival, as sodium is essential for fluid homeostasis, cardiovascular function, and cellular processes. However, excessive salt intake poses a significant public health challenge, contributing to hypertension, cardiovascular disease, and re...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Trace S Kershaw

YALE UNIVERSITY, NEW HAVEN, CT

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,199,210

FY 2026

Project Title

Theoretically Informed Behavioral Intervention to Enhance QOL and Prevent HIV-related Comorbidities

Grant Number:

5R01MD019956-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Black and Hispanic men are at highest risk of comorbid conditions resulting from HIV. Cardiovascular disease has become the leading contributor to mortality among persons with HIV, as both conditions are often co-morbid. As a result, prominent HIV comorbid conditions include CVD, high blood...

Research Terms

<7 year old><7 years of age><AIDS Virus><AIDS prevention><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Adult-Onset Diabetes Mellitus><Affect><Age><Apoplexy><Application Context><Area><BMI><BMI percentile><BMI z-score><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biological><Blood Glucose><Blood Sugar><Blood Vessels><Body mass index><Brain Vascular Accident><Cancers><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cause of Death><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chest Pain><Cholesterol><Chronic><Chronic Disease><Chronic Illness><Clinic><Clinical><Clinical Trials><Communities><Conditioning Therapy><Counseling><Data><Dietary quality><Direct Expenditure><Economic Burden><Educational process of instructing><Enrollment><Environment Design><Financial Hardship><Follow-Up Studies><Funding><General Population><General Public><Goals><HIV><HIV Infections><HIV Prevention><HIV individuals><HIV infected individuals><HIV infected men><HIV infected persons><HIV intervention><HIV load><HIV people><HIV plasma viral load><HIV positive individuals><HIV positive men><HIV positive people><HIV therapeutic><HIV therapy><HIV treatment><HIV viral burden><HIV viral infection><HIV viral load><HIV virus infection><HIV+ men><HIV-1 infection><HIV-1 intervention><HIV-1 load><HIV-1 prevention><HIV-1 therapeutic><HIV-1 therapy><HIV-1 treatment><HIV-1 viral burden><HIV-1 viral load><HIV/AIDS prevention><Health><Health Care><Health Care Utilization><Health Promotion><Heart><Heart Diseases><Heart Vascular><Hispanic male><Hispanic men><Human><Human Immunodeficiency Virus therapy><Human Immunodeficiency Virus treatment><Human Immunodeficiency Viruses><Hypertension><Immune Cell Activation><Incidence><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Inflammation><Intervention><Intervention Studies><Ketosis-Resistant Diabetes Mellitus><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Males living with HIV><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Measurable><Medical Care Costs><Men with HIV><Metabolic><Metabolic Diseases><Metabolic Disorder><Methods><Modern Man><NCMHD><NIDDM><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><PLWH><PWH><Participant><Patient Education><Patient Instruction><Patient Training><Patients><Persons><Physical activity><Policies><Population><Prevent HIV><Preventative screening><Prevention><Prevention education><Preventive screening><Problem Solving><Psyche structure><QOL><Quality of life><Quetelet index><Reporting><Research><Risk><Risk Factors><Salutogenesis><Scientific Advances and Accomplishments><Sleep Deprivation><Slow-Onset Diabetes Mellitus><Social support><Stable Diabetes Mellitus><Stroke><T2 DM><T2D><T2DM><Teaching><Technology><Testing><Thesaurismosis><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Unhealthy Diet><United States><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Virtual Tool><Virus-HIV><Waiting Lists><acceptability and feasibility><adult onset diabetes><age 7><age 7 years><ages><behavior intervention><behavioral clinical trial><behavioral intervention><biologic><black male><black man><black men><blood pressure elevation><brain attack><cancer risk><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><care costs><care seeking><cerebral vascular accident><cerebrovascular accident><chronic disorder><circulatory system><clinical practice><clinical risk><co-morbid><co-morbidity><collaboration with communities><community collaboration><community-based collaboration><comorbidity><contextual factors><control trial><deficient sleep><determine efficacy><diet quality><disparity in health><e-Health><eHealth><economic hardship><economic strain><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><electronic health><elevated blood pressure><enroll><evaluate efficacy><examine efficacy><experience><exposure to nicotine><federal poverty level><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><follow-up research study><follow-up survey><health care service use><health care service utilization><health disparity><heart disorder><high blood pressure><high risk men><human immunodeficiency virus infection><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><immune activation><improved><inadequate sleep><increase in blood pressure><increased blood pressure><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><innovate><innovation><innovative><insufficient sleep><interpersonal conflict><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><malignancy><man living with HIV><maturity onset diabetes><medical costs><medical expenses><men at high risk><men diagnosed with HIV><men infected with HIV><men living with HIV><mental><metabolism disorder><mortality><multidisciplinary><neoplasm/cancer><nicotine exposure><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><poor diet><prevent AIDS><prevent human immunodeficiency virus><process evaluation><promoting health><public health relevance><risk sharing><scientific accomplishments><scientific advances><seven year old><seven years of age><sexual minority men><sleep debt><sleep deficiency><sleep deficit><sleep insufficiency><sleep loss><social determinants><social stigma><social support network><sociodeterminant><stigma><stroked><strokes><study with follow-up><treat HIV><treat Human Immunodeficiency Virus><type 2 DM><type II DM><type two diabetes><uptake><vascular><virtual environment><waitlist>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Silvia Raquel Ramos

YALE UNIVERSITY, NEW HAVEN, CT

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,199,210

FY 2026

Project Title

Theoretically Informed Behavioral Intervention to Enhance QOL and Prevent HIV-related Comorbidities

Grant Number:

5R01MD019956-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Black and Hispanic men are at highest risk of comorbid conditions resulting from HIV. Cardiovascular disease has become the leading contributor to mortality among persons with HIV, as both conditions are often co-morbid. As a result, prominent HIV comorbid conditions include CVD, high blood...

Research Terms

<7 year old><7 years of age><AIDS Virus><AIDS prevention><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Adult-Onset Diabetes Mellitus><Affect><Age><Apoplexy><Application Context><Area><BMI><BMI percentile><BMI z-score><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biological><Blood Glucose><Blood Sugar><Blood Vessels><Body mass index><Brain Vascular Accident><Cancers><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cause of Death><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chest Pain><Cholesterol><Chronic><Chronic Disease><Chronic Illness><Clinic><Clinical><Clinical Trials><Communities><Conditioning Therapy><Counseling><Data><Dietary quality><Direct Expenditure><Economic Burden><Educational process of instructing><Enrollment><Environment Design><Financial Hardship><Follow-Up Studies><Funding><General Population><General Public><Goals><HIV><HIV Infections><HIV Prevention><HIV individuals><HIV infected individuals><HIV infected men><HIV infected persons><HIV intervention><HIV load><HIV people><HIV plasma viral load><HIV positive individuals><HIV positive men><HIV positive people><HIV therapeutic><HIV therapy><HIV treatment><HIV viral burden><HIV viral infection><HIV viral load><HIV virus infection><HIV+ men><HIV-1 infection><HIV-1 intervention><HIV-1 load><HIV-1 prevention><HIV-1 therapeutic><HIV-1 therapy><HIV-1 treatment><HIV-1 viral burden><HIV-1 viral load><HIV/AIDS prevention><Health><Health Care><Health Care Utilization><Health Promotion><Heart><Heart Diseases><Heart Vascular><Hispanic male><Hispanic men><Human><Human Immunodeficiency Virus therapy><Human Immunodeficiency Virus treatment><Human Immunodeficiency Viruses><Hypertension><Immune Cell Activation><Incidence><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Inflammation><Intervention><Intervention Studies><Ketosis-Resistant Diabetes Mellitus><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Males living with HIV><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Measurable><Medical Care Costs><Men with HIV><Metabolic><Metabolic Diseases><Metabolic Disorder><Methods><Modern Man><NCMHD><NIDDM><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><PLWH><PWH><Participant><Patient Education><Patient Instruction><Patient Training><Patients><Persons><Physical activity><Policies><Population><Prevent HIV><Preventative screening><Prevention><Prevention education><Preventive screening><Problem Solving><Psyche structure><QOL><Quality of life><Quetelet index><Reporting><Research><Risk><Risk Factors><Salutogenesis><Scientific Advances and Accomplishments><Sleep Deprivation><Slow-Onset Diabetes Mellitus><Social support><Stable Diabetes Mellitus><Stroke><T2 DM><T2D><T2DM><Teaching><Technology><Testing><Thesaurismosis><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Unhealthy Diet><United States><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Virtual Tool><Virus-HIV><Waiting Lists><acceptability and feasibility><adult onset diabetes><age 7><age 7 years><ages><behavior intervention><behavioral clinical trial><behavioral intervention><biologic><black male><black man><black men><blood pressure elevation><brain attack><cancer risk><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><care costs><care seeking><cerebral vascular accident><cerebrovascular accident><chronic disorder><circulatory system><clinical practice><clinical risk><co-morbid><co-morbidity><collaboration with communities><community collaboration><community-based collaboration><comorbidity><contextual factors><control trial><deficient sleep><determine efficacy><diet quality><disparity in health><e-Health><eHealth><economic hardship><economic strain><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><electronic health><elevated blood pressure><enroll><evaluate efficacy><examine efficacy><experience><exposure to nicotine><federal poverty level><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><follow-up research study><follow-up survey><health care service use><health care service utilization><health disparity><heart disorder><high blood pressure><high risk men><human immunodeficiency virus infection><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><immune activation><improved><inadequate sleep><increase in blood pressure><increased blood pressure><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><innovate><innovation><innovative><insufficient sleep><interpersonal conflict><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><malignancy><man living with HIV><maturity onset diabetes><medical costs><medical expenses><men at high risk><men diagnosed with HIV><men infected with HIV><men living with HIV><mental><metabolism disorder><mortality><multidisciplinary><neoplasm/cancer><nicotine exposure><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><poor diet><prevent AIDS><prevent human immunodeficiency virus><process evaluation><promoting health><public health relevance><risk sharing><scientific accomplishments><scientific advances><seven year old><seven years of age><sexual minority men><sleep debt><sleep deficiency><sleep deficit><sleep insufficiency><sleep loss><social determinants><social stigma><social support network><sociodeterminant><stigma><stroked><strokes><study with follow-up><treat HIV><treat Human Immunodeficiency Virus><type 2 DM><type II DM><type two diabetes><uptake><vascular><virtual environment><waitlist>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DENISA D WAGNER

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,177,050

FY 2026

Project Title

Inflammation and thrombosis fuel cardiovascular and pulmonary disease: Focus on the interplay of neutrophil inflammasomes with NETs

Grant Number:

5R35HL166556-04

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2023

End Date:

2/28/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Inflammation and thrombosis fuel cardiovascular and pulmonary disease: Focus on the interplay of neutrophil inflammasomes with NETs. For many years, we have conducted a successful research program studying the links between thrombosis and inflammation. We plan to continue this line of investigation ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Matthias Nahrendorf

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,105,242

FY 2026

Project Title

Macrophages in Cardiovascular Health

Grant Number:

5R35HL176359-02

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2025

End Date:

1/31/2032

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Inflammation is seen as an unrealized therapeutic opportunity in cardiovascular disease (CVD), and the field is poised to recapitulate immunomodulatory drug breakthroughs that recently happened for cancer patients. In this application, I propose expanding our understanding of innate immunity in CVD,...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Colin G Nichols

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,034,314

FY 2026

Project Title

Cardiovascular potassium channels: From molecular basis to disease therapeutics

Grant Number:

5R35HL171542-03

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract My lab studies the mechanistic basis, and functional consequences, of ion channels, particularly inward rectifier (Kir) and ATP-sensitive (KATP) potassium channels, found throughout the cardiovascular system. Our work integrates studies at multiple levels, from the fundamental molecular bas...

Research Terms

<21+ years old><Address><Adult><Adult Human><Animal Model><Animal Models and Related Studies><Animals><Biochemical><Biological><Blood Vessels><Cantu syndrome><Cardiac><Cardiac Output><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Pathology><Cardiovascular Physiology><Cardiovascular system><Cell Body><Cell model><Cells><Cellular model><Clinic><DNA mutation><Development><Disease><Disorder><Genes><Genetic Change><Genetic defect><Genetic mutation><Heart Vascular><Human><Individual><Intermediary Metabolism><Involuntary Muscle><Ion Channel><Ionic Channels><K channel><Link><Lymphedema><Membrane Channels><Metabolic Processes><Metabolism><Modern Man><Molecular><Motility><Mutation><Myocardium><Nature><Neonatal Mortality><Pathologic><Pathology><Pericardial effusion><Peripheral Resistance><Persistent Fetal Circulation><Persistent Fetal Circulation Syndrome><Physiologic><Physiological><Potassium Channel><Potassium Ion Channels><Proteins><Regulation><Research><Role><Smooth Muscle><Systemic Vascular Resistance><Therapeutic><Total Peripheral Resistance><Work><adulthood><biologic><cardiac dimension><cardiac muscle><cardiac size><cardiovascular disorder><cardiovascular function><circulatory system><death among neonates><death among newborns><death in neonates><death in newborn><developmental><dwarfism-cerebral atrophy-keratosis follicularis syndrome><gain of function><genome mutation><heart dimension><heart dimension/size><heart muscle><heart output><heart size><human disease><interest><lymph edema><lymphatic edema><model of animal><mortality among neonates><mortality among newborns><mortality in neonates><mortality in newborns><neonatal death><neonatal demise><newborn death><newborn mortality><novel><pharmacologic><social role><tool><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ELIZABETH B LYNCH

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Good lead · 68/100

Likely hiring

Above-average budget

Active award

Team-scale grant

$745,235

FY 2026

Project Title

VITAL: Vital Investments To Advance Life expectancy

Grant Number:

5U01AG094351-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Large and persistent gaps in life expectancy between Black and White people, which approach ten years in major U.S. cities, represent an important public health challenge. It is increasingly recognized that social and environmental neighborhood conditions resulting from disinvestment in segregated B...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Adam Carl Straub

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$929,138

FY 2026

Project Title

Basic and Translational Studies in Redox Regulation of Cardiovascular Physiology and Disease

Grant Number:

5R35HL161177-05

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Our research program seeks to elucidate the chemistry, biology and translational impact of “redox switches” in the cardiovascular system. Our work has revealed that cytochrome b5 reductase 3 (CYB5R3) operates as a critical redox switch in the cardiovascular system by reducing substrates suc...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eric Gerald Krause

GEORGIA STATE UNIVERSITY, ATLANTA, GA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$917,281

FY 2026

Project Title

Interrogating stress-relieving neural circuits to alleviate cardiovascular disease

Grant Number:

5R35HL150750-07

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/5/2020

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Stressful life events are linked to the etiology of cardiovascular disease (CVD), which is the leading cause of death in the U.S. The mechanisms by which stress causes pathophysiology contributing to CVD are poorly understood and effective therapeutics that relieve stress and improve...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stanley L Hazen

CLEVELAND CLINIC LERNER COM-CWRU, CLEVELAND, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$780,467

FY 2026

Project Title

Artificial sweeteners and cardiovascular disease

Grant Number:

5R01HL172805-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/4/2025

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary This application is entitled “Artificial sweeteners and cardiovascular disease”. The proposed studies investigate whether low calorie, non-nutritive sweeteners (NNS’s), and commonly employed artificial sweeteners, contribute to the development of cardiovascular disease (CVD) through ...

Research Terms

<1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide><ASCVD><Address><Adopted><Adoption><Agonist><Alditols><Animal Disease Models><Animal Model><Animal Models and Related Studies><Apoplexy><Arterial Fatty Streak><Arterial Injury><Artificial Sweeteners><Aspartame><Assay><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Bioassay><Biological Assay><Blood><Blood Plasma><Blood Platelets><Blood Reticuloendothelial System><Blood Vessels><Blood leukocyte><Brain Vascular Accident><Calories><Cardiac infarction><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cell Communication><Cell Interaction><Cell model><Cell-to-Cell Interaction><Cells><Cellular model><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Chemicals><Clinical><Clinical Research><Clinical Study><Collagen><Consumption><Coronary><Data><Death><Development><Diet><Endothelial Cells><Enzyme Gene><Enzymes><Epidemiological data><Epidemiology data><European><Event><Experimental Models><Fasting><Food><Food Industry><Friends><Fructose><GI microbiome><GWA study><GWAS><Generations><Genetic><Glucosiduronates><Glucuronates><Glycosides><Health><Heart Vascular><Hexose Monophosphate Shunt><Human><Intermediary Metabolism><Investigation><Isomerism><Knock-out><Knockout><Knowledge><LC/MS><Leukocytes><Leukocytes Reticuloendothelial System><Levulose><Link><Lyxulose><Marrow leukocyte><Marrow platelet><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Medicine><Metabolic Processes><Metabolism><Methodology><Mice><Mice Mammals><Modern Man><Modernization><Murine><Mus><Myocardial Infarct><Myocardial Infarction><Nature><Observational Study><Pathogenesis><Pathway interactions><Pentose Phosphate Pathway><Pentose Phosphate Shunt><Pentose Shunt><Pentosephosphate Pathway><Pentosephosphate Shunt><Phenotype><Phosphates><Physiologic><Physiological><Plasma><Plasma Serum><Platelets><Pre-Clinical Model><Preclinical Models><Process><Publishing><Research><Residual><Residual state><Reticuloendothelial System, Serum, Plasma><Risk><Risk Assessment><Risk Factors><Role><Saccharin><Safety><Sampling><Stroke><Study models><Sugar Alcohols><Sweeteners><Sweetening Agents><Testing><Thrombase><Thrombin><Thrombocytes><Thrombosis><Validation><Vascular Diseases><Vascular Disorder><Vascular Endothelium><White Blood Cells><White Cell><Whole Blood><Xylitol><Xylulose><atheromatosis><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic vascular disease><blood vessel disorder><brain attack><calorie><cardiac infarct><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cerebral vascular accident><cerebrovascular accident><circulatory system><cohort><coronary attack><coronary infarct><coronary infarction><developmental><diabetes control><diabetes mellitus control><diets><digestive tract microbiome><disease risk><disorder risk><enteric microbiome><epidemiologic data><experience><fasted><fasts><fibrinogenase><gastrointestinal microbiome><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><gulonate><gut microbiome><gut-associated microbiome><heart attack><heart infarct><heart infarction><human subject><improved><in vivo><indexing><injury to the vasculature><inorganic phosphate><intestinal biome><intestinal microbiome><intra-vital microscopy><intravital microscopy><isomer><knock-down><knockdown><liquid chromatography mass spectrometry><metabolism measurement><metabolomics><metabonomics><model of animal><mouse model><multidisciplinary><murine model><new diagnostics><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation diagnostics><next generation therapeutics><novel diagnostics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><observational research study><observational survey><pathway><phospho-proteomics><phosphoproteomics><plaques in atherosclerosis><polyol><social role><stable isotope><stroked><strokes><sugar><thrombotic disease><thrombotic disorder><ultrasound><validations><vascular><vascular dysfunction><vascular inflammation><vascular injury><vasculopathy><white blood cell><white blood corpuscle><whole genome association analysis><whole genome association study>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Daniel Joseph Conklin

UNIVERSITY OF LOUISVILLE, LOUISVILLE, KY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$778,558

FY 2026

Project Title

Cardiopulmonary Toxicity of Electronic Nicotine Delivery Systems

Grant Number:

5R01HL171763-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/14/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Cardiopulmonary Toxicity of Electronic Nicotine Delivery Systems Although electronic nicotine delivery systems (ENDS) are widely used by youth and young adults, the toxicity and the health effects of these products remain unclear. Many types of devices with varying constituents have been introduced ...

Research Terms

<2-Propenal><Acraldehyde><Acrolein><Acrylaldehyde><Acrylic Aldehyde><Address><Aerosols><Affect><Allyl Aldehyde><Animal Model><Animal Models and Related Studies><Biological Markers><Carbon Monoxide><Cardiac><Cardiopulmonary><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Characteristics><Data><Dependence><Development><Devices><Electronic Nicotine Delivery Product><Electronic Nicotine Delivery Systems><Electronic cigarette><Ethylene Aldehyde><Evaluation><Exposure to><Flavorant><Flavoring><Flavoring Agents><Food and Drug Administration><Formaldehyde><Formic Aldehyde><Generations><Health><Heart Vascular><Individual><Link><Marketing><Measures><Mediating><Metals><Methyl Aldehyde><Mice><Mice Mammals><Modeling><Murine><Mus><Nicotine><Oxomethane><Pattern><Policies><Production><Propanediols><Propylene Glycols><Protocol><Protocols documentation><Public Health><Regulation><Risk><Role><Solvents><Tars><Technology><Testing><Toxic effect><Toxicities><USFDA><United States Food and Drug Administration><Urine><Work><Youth><Youth 10-21><acryaldehyde><adult youth><bio-markers><biologic marker><biomarker><biomarker identification><cardiovascular function><circulatory system><co-exposures><co-occurring exposure><combined exposure><combustible cigarette><complex exposure><concurrent exposure><conventional cigarette><design><designing><developmental><disease risk><disorder risk><e-cig><e-cig aerosols><e-cig liquids><e-cig use><e-cig vapor><e-cigarette><e-cigarette aerosols><e-cigarette liquids><e-cigarette use><e-cigarette vapor><e-juice><e-liquid><ecig><ecig aerosols><ecig liquids><ecig use><ecig vapor><ecigarette><ecigarette aerosols><ecigarette liquids><ecigarette use><ecigarette vapor><ejuice><electronic cigarette aerosol><electronic cigarette use><electronic cigarette vapor><electronic liquid><electronic nicotine delivery device><electronic nicotine distribution system><eliquid><evidence base><exposure mixture><exposure to nicotine><hemodynamics><identification of biomarkers><identification of new biomarkers><lung function><manufacture><marker identification><mixed exposure><model of animal><nicotine exposure><novel><pod mods><pollutant><pulmonary><pulmonary function><simultaneous exposures><social role><tobacco ads><tobacco advertising><tobacco marketing><tobacco product advertising><tobacco products><traditional cigarette><vegetable glycerin><volatile organic chemical><volatile organic compound><young adult><young adult age><young adulthood><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PETER J TONTONOZ

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$756,712

FY 2026

Project Title

Membrane cholesterol and vascular inflammation

Grant Number:

5R01HL175240-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2024

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Our long-term objective is to define cellular pathways that regulate lipid flux and to elucidate their impact on cardiovascular disease. Although the connection between hypercholesterolemia and vascular inflammation has been appreciated for decades, the mechanistic underpinnings of this ass...

Research Terms

<7B4><ASCVD><Adhesion Molecule><Affect><Animals><Assay><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Binding><Binding Proteins><Bioassay><Biological Assay><Biology><Blood Vessels><Body Tissues><CD106><CD106 Antigens><CD54 Antigens><CDH5><CDH5 gene><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Adhesion Molecule Gene><Cell Adhesion Molecules><Cell Body><Cell Communication and Signaling><Cell Function><Cell Membrane Lipids><Cell Physiology><Cell Process><Cell Signaling><Cell Surface Proteins><Cell membrane><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chemicals><Chemistry><Cholesterol><Cholesterol Homeostasis><Cytoplasmic Membrane><Data><Development><Diet><Disease><Disorder><Endoplasmic Reticulum><Endothelial Cells><Endothelium><Equilibrium><Ergastoplasm><Family><Gene Expression><HDL Cholesterol><HDL Cholesterol Lipoproteins><Heart Vascular><High Density Lipoprotein Cholesterol><Hypercholesteremia><ICAM-1><INCAM-110><Immune><Immunes><Inducible Cell Adhesion Molecule 110><Inflammation><Inflammatory><Inflammatory Response><Intercellular adhesion molecule 1><Intracellular Communication and Signaling><Knowledge><LDL><LDL Lipoproteins><Ligand Binding Protein><Ligand Binding Protein Gene><Lipid Trafficking><Lipids><Low-Density Lipoproteins><Membrane><Membrane Lipids><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Mice><Mice Mammals><Modeling><Molecular><Molecular Interaction><Movement><Murine><Mus><Pathology><Pathway interactions><Phenotype><Physiology><Plasma Membrane><Protein Binding><Proteins><Receptor Protein><Regulation><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Sterols><Stimulus><Stress><Subcellular Process><Surface Proteins><System><Therapeutic Intervention><Tissues><VCAM><VCAM-1><Validation><Vascular Cell Adhesion Molecule><Vascular Cell Adhesion Molecule-1><Vascular Endothelium><Work><alpha-Lipoprotein Cholesterol><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><balance><balance function><beta-Lipoproteins><biological signal transduction><body movement><bound protein><cardiovascular disorder><cell adhesion protein><cell type><cholesterol metabolism><cholesterol-binding protein><circulatory system><comparative><crosslink><developmental><diets><high blood cholesterol><hypercholesterolemia><in vivo><insight><intervention therapy><lipid transport><loss of function><membrane structure><mimetics><novel><oxidized lipid><pathway><plasmalemma><receptor><recruit><response><social role><uptake><validations><vascular><vascular inflammation>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stefania Nicoli

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$754,075

FY 2026

Project Title

Defining the cellular and molecular formation of the sympathetic neurovascular unit

Grant Number:

5R01HL170949-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/8/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Our long-term goal is to understand the cellular and genetic rules governing how endothelial cells (EC), vascular smooth muscle cells (VSMC) and sympathetic neurons (SN) interact within the artery. SNs innervate vascular SMCs and control normal vascular functions such as ci...

Research Terms

<21+ years old><Address><Adult><Adult Human><Affect><Animals><Aorta><Area><Arteries><Assay><Autoregulation><Basic Research><Basic Science><Bioassay><Biological Assay><Biophysics><Birth Defects><Bleeding><Blood Pressure><Blood Vessels><Blood flow><Body Temperature><Body Tissues><Brachydanio rerio><Cardiac Malformation><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Pathology><Cardiovascular system><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Circulation><Co-culture><Cocultivation><Coculture><Coculture Techniques><Collaborations><Complex><Congenital Abnormality><Congenital Anatomical Abnormality><Congenital Cardiovascular Abnormality><Congenital Cardiovascular Anomaly><Congenital Cardiovascular Defects><Congenital Cardiovascular Malformations><Congenital Defects><Congenital Deformity><Congenital Malformation><Danio rerio><Data><Defect><Dependence><Disease><Disorder><Dorsal><Dysfunction><Embryo><Embryo Development><Embryogenesis><Embryonic><Embryonic Development><Endothelial Cells><Event><Experimental Designs><Functional disorder><Genes><Genetic><Goals><Heart Malformation><Heart Vascular><Hemorrhage><Homeostasis><Human><Image><In Vitro><Individual><Intermediary Metabolism><Intracellular Communication and Signaling><Investigators><Knowledge><Leiomyocyte><Life><Link><Maintenance><Maps><Mediating><Metabolic Processes><Metabolism><Mice><Mice Mammals><Microfluidics><Modeling><Modern Man><Molecular><Morphogenesis><Murine><Mus><Nerve Cells><Nerve Unit><Neural Cell><Neural Stem Cell><Neurocyte><Neuronal Differentiation><Neurons><O element><O2 element><Oxygen><Paracrine Communication><Paracrine Signaling><Pathway interactions><Patients><Persons><Phenotype><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Proliferating><Regulation><Research Personnel><Researchers><Respiration><Science><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Subcellular Process><Sympathetic Nervous System><System><Testing><Therapeutic><Tissues><Translating><Vascular Endothelial Cell><Vascular Smooth Muscle><Vascular System><Vascular remodeling><Vertebrate Animals><Vertebrates><Work><Zebra Danio><Zebra Fish><Zebrafish><abnormal heart development><adulthood><arterial remodeling><biological signal transduction><biophysical approaches><biophysical foundation><biophysical methodology><biophysical methods><biophysical principles><biophysical sciences><biophysical techniques><blood loss><blood vessel development><blood vessel formation><candidate identification><cell behavior><cell type><cellular behavior><circulatory system><congenital cardiac abnormality><congenital cardiac anomalies><congenital cardiac disease><congenital cardiac disorder><congenital cardiac malformation><congenital cardiovascular disease><congenital cardiovascular disorder><congenital heart abnormality><congenital heart anomaly><congenital heart disease><congenital heart disorder><congenital heart malformation><constriction><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><hemodynamics><human model><imaging><imaging approach><imaging based approach><improved><in vivo><innervation><live cell image><live cell imaging><live cellular image><live cellular imaging><microscope imaging><microscopic imaging><microscopy imaging><migration><model of human><morphogenetic process><mouse model><murine model><nerve stem cell><nerve supply><neural precursor><neural precursor cell><neural progenitor><neural progenitor cells><neural stem and progenitor cells><neuro-vascular><neuro-vascular coupling><neuro-vascular unit><neurogenic progenitors><neurogenic stem cell><neuron component><neuron progenitors><neuronal><neuronal progenitor><neuronal progenitor cells><neuronal stem cells><neuroprogenitor><neurovascular><neurovascular coupling><neurovascular unit><novel><pathophysiology><pathway><postnatal><progenitor and neural stem cells><programs><repair><repaired><respiratory mechanism><shear stress><stem><vascular><vertebrata><µfluidic>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David J Fulton

AUGUSTA UNIVERSITY, AUGUSTA, GA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$751,582

FY 2026

Project Title

Skeletal Muscle Health Protects Vascular Function in Obesity

Grant Number:

5R01HL176793-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity remains the most persistent threat to cardiovascular health in the United States. Exercise mitigates much of this risk, but the therapeutic benefits of exercise are frequently beyond the capabilities of the aged, the very obese or those with prior injuries. Understanding the...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David W Stepp

AUGUSTA UNIVERSITY, AUGUSTA, GA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$751,582

FY 2026

Project Title

Skeletal Muscle Health Protects Vascular Function in Obesity

Grant Number:

5R01HL176793-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity remains the most persistent threat to cardiovascular health in the United States. Exercise mitigates much of this risk, but the therapeutic benefits of exercise are frequently beyond the capabilities of the aged, the very obese or those with prior injuries. Understanding the...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JAY Louis ZWEIER

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$749,772

FY 2026

Project Title

Role of Cytoglobin in the Regulation of Vascular Tone

Grant Number:

5R01HL131941-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2017

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Endothelium-derived nitric oxide (NO), is a key mediator regulating vascular tone and blood pressure. NO mediates vascular relaxation through activation of soluble guanylate cyclase (sGC) in the smooth muscle. While NO is synthesized by NO synthase in the endothelium, the process of vascular NO degr...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Irina Bancos

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$741,387

FY 2026

Project Title

Reversing abnormal metabolism in mild autonomous cortisol secretion (MACS)

Grant Number:

1R01DK145578-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/20/2026

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Mild autonomous cortisol secretion (MACS) is diagnosed in up to 44% of patients with adrenal adenomas, affecting 1-2% of the adult population. MACS is diagnosed based on an abnormal cortisol level following dexamethasone suppression (>1.8 mcg/dL). Patients with MACS develop high rate...

Research Terms

<2-methyl-1,2-di-3-pyridinyl-1-propanone><21+ years old><ACTH><Acceleration><Acetylation><Address><Adrenal Adenoma><Adrenal Gland Adenoma><Adrenal Gland Excision><Adrenal Gland Insufficiency><Adrenal Glands><Adrenal Insufficiency><Adrenal gland hypofunction><Adrenalectomy><Adrenals><Adrenocorticotropic Hormone><Adrenocorticotropin><Adult><Adult Human><Adverse Experience><Adverse event><Aeroseb-HC><Affect><Androgenic Agents><Androgenic Compounds><Androgens><Award><Benign Adrenal Adenoma><Benign Adrenal Gland Adenoma><Bilateral><Biological Markers><Blood Serum><Branched-Chain Amino Acids><CDK4I><CDKN2><CDKN2 Genes><CDKN2A><CDKN2A gene><CMM2><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cell Aging><Cell Senescence><Cellular Aging><Cellular Senescence><Cetacort><Circadian Rhythms><Clinical Trials><Cognition><Communication><Cort-Dome><Cortef><Cortenema><Corticotropin><Cortisol><Cortisone><Cortispray><Cortril><Cushing Syndrome><Cushing's basophilism><Cyclin-Dependent Kinase Inhibitor 2A Gene><Data><Dermacort><Dexamethasone><Diagnosis><Dose><Dyslipidemias><Eldecort><Event><FDA approved><Feedback><Glucocorticoids><Glycoproteins><Health><Heart Vascular><Hormonal><Hydrocortisone><Hydrocortone><Hypertension><Hypoadrenalism><Hypophysis><Hypophysis Cerebri><Hypothalamic structure><Hypothalamus><Hytone><INK4><INK4A><Impairment><Inflammation><Intermediary Metabolism><Intervention><Interview><Lead><Lipoproteins><MTS1><MTS1 Genes><Measurement><Medical><Metabolic><Metabolic Processes><Metabolism><Methbipyranone><Methopyrapone><Metyrapone><Morbidity><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Nutracort><Nyctohemeral Rhythm><Outcome><Patients><Pb element><Pituitary><Pituitary Gland><Pituitary Nervous System><Population><Prevalence><Proctocort><Questionnaires><Randomized><Relative Risks><Replicative Senescence><Research><Safety><Salivary><Serum><Steroid Compound><Steroid biosynthesis><Steroids><Symptoms><T-Cells><T-Lymphocyte><TP16><TSG9A><Testing><Therapeutic Androgen><Twenty-Four Hour Rhythm><United States><Urine><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Withdrawal><adulthood><arm><bio-markers><biologic marker><biomarker><bone health><branched amino acids><cardiovascular risk><cardiovascular risk factor><circadian><circadian process><circadian rhythmicity><circulatory system><daily biorhythm><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><frailty><heavy metal Pb><heavy metal lead><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypothalamic><improved><inflammation marker><inflammatory marker><inhibitor><metabolic phenotype><metabolome><metabonome><metabotype><mortality><natural aging><normal aging><normative aging><open label><open label study><p14ARF><p16 Genes><p16INK4 Genes><p16INK4A Genes><p16INK4a><patient population><peripheral blood><pituitary basophilism><post intervention><randomisation><randomization><randomly assigned><replicative aging><senescence><senescent><steroidogenesis><suprarenal gland><systemic inflammation><systemic inflammatory response><thymus derived lymphocyte>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Ouyang

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$733,096

FY 2026

Project Title

Artificial Intelligence Imaging Biomarkers of Longitudinal Cardiovascular Stress

Grant Number:

5R01HL173487-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Across every type of prediction model, applied to virtually any population, the single most substantial contributor to incident cardiovascular disease (CVD) is older age. However, our understanding of why cardiovascular risk dramatically rises with advancing age remains limited. Evidence to...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AI based method><AI based model><AI model><AI system><Acceleration><Adult><Adult Human><Age><Aged 65 and Over><Aging><Artificial Intelligence><Biological><Biological Markers><California><Cardiac><Cardiac Abnormalities><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Characteristics><Chronology><Clinical><Cohort Analyses><Cohort Analysis><Cohort Studies><Communities><Computer Reasoning><Data><Derivation><Derivation procedure><Diabetes Mellitus><Diagnosis><Disease Outcome><Dysfunction><Echocardiogram><Echocardiography><Elderly><Epidemiology><Exposure to><Eye><Eyeball><Framingham Heart Study><Functional disorder><Goals><Health Care><Health Care Systems><Health system><Heart Abnormalities><Heart Diseases><Heart Vascular><Hospitals><Human><Hypertension><Image><Incidence><Individual><Inflammation><Injury><Machine Intelligence><Maps><Measurement><Measures><Medical Imaging><Medical center><Methods><Modeling><Modern Man><Multi-Ethnic Study of Atherosclerosis><Muscle Cells><Myocytes><Outcome><Output><Participant><Pathway interactions><Patients><Pattern><Performance><Persons><Phenotype><Physiopathology><Population><Prognostic Marker><Risk><Risk Factors><Smoking><Stress><Structure><Testing><Time><Training><Transthoracic Echocardiography><United States><Validation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><above age 65><accelerated aging><accelerated biological age><accelerated biological aging><accumulated exposure><accumulated long-term exposure><adulthood><advanced age><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age acceleration><age associated><age associated alterations><age associated changes><age correlated><age correlated alterations><age correlated changes><age dependent><age dependent alterations><age dependent changes><age induced alterations><age induced changes><age linked><age of 65 years onward><age related><age related alterations><age related changes><age specific><age specific alterations><age specific changes><aged 65 and greater><aged 65+><aged ≥65><ages><aggregate exposure><aging associated alterations><aging associated changes><aging correlated alterations><aging correlated changes><aging delay><aging dependent alterations><aging dependent changes><aging induced alterations><aging induced changes><aging related alterations><aging related changes><aging specific alterations><aging specific changes><alterations with age><applied learning><artificial intelligence method><artificial intelligence model><artificial intelligence-based model><attenuate aging><bio-markers><biologic><biologic marker><biological age><biological sex><biomarker><biomedical imaging><cardiac aging><cardiac imaging><cardiac scanning><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular imaging><cardiovascular risk><cardiovascular risk factor><changes with age><circulatory system><clinical care><cohort><cohort research study><cohort survey><community setting><comparative><computer based prediction><coronary artery calcium><coronary calcium><cumulative exposure><cumulative life exposure><cumulative long-term exposure><decelerate aging><deep learning><deep learning algorithm><deep learning method><deep learning strategy><delay age related><diabetes><disease phenotype><epidemiologic><epidemiological><epidemiology research study><epidemiology study><epidemiology survey><geriatric><hands-on learning><health care settings><heart aging><heart disorder><heart imaging><heart scanning><heart sonography><high blood pressure><high dimensionality><human old age (65+)><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><injuries><interactive engagement><interactive learning><life span><life-course exposure><lifelong exposure><lifespan><lifespan exposure><lifetime exposure><longitudinal imaging><neural network><old age><over 65 years><pathophysiology><pathway><pause aging><postpone age related><predictive modeling><prognostic biomarker><prognostic indicator><public health relevance><retards aging><senior citizen><serial imaging><slow aging><slow down aging><slow the rate of aging><spatial and temporal><spatial temporal><spatiotemporal><standard measure><totality of exposures><trait><validations><virtual><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yunmeng Liu

UNIV OF ARKANSAS FOR MED SCIS, LITTLE ROCK, AR

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$717,457

FY 2026

Project Title

Metabolic Rewiring of T Cells Bridges Diabetes to Hypertension

Grant Number:

1R01DK145683-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2026

End Date:

11/30/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY / ABSTRACT Metabolic syndrome persists as a leading cause of morbidity and mortality among adults in the United States. Specifically, the co-existence of diabetes and hypertension, hallmark components of metabolic syndrome, stand as primary contributors to cardiovascular disease and...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Attention><Attenuated><Autocrine Systems><Automobile Driving><Blood Plasma><Blood Pressure><Body Tissues><Bone-Derived Transforming Growth Factor><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Calcium><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cessation of life><Chronic><Complex><Coupled><D-Glucose><Dangerousness><Death><Development><Dextrose><Diabetes Mellitus><Diabetic mouse><Disease><Disorder><Dysfunction><Event><Feedback><Functional disorder><Glucose><Health><Heart Diseases><Heart Vascular><High Fat Diet><Humulin R><Hyperinsulinemia><Hyperinsulinism><Hypertension><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><Immune><Immune Interferon><Immunes><Immunology><Immunotherapeutic agent><Infiltration><Insulin><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin-Dependent Tyrosine Protein Kinase><Interferon Gamma><Interferon Type II><Intermediary Metabolism><Intervention><Intracellular Communication and Signaling><Investigation><KO mice><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Link><Mature T-Cell><Mature T-Lymphocyte><Maturity-Onset Diabetes Mellitus><Mediating><Metabolic><Metabolic Activation><Metabolic Pathway><Metabolic Processes><Metabolic syndrome><Metabolism><Mice><Mice Mammals><Milk Growth Factor><Modeling><Morbidity><Murine><Mus><NCC gene><NCC protein><NCCT><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Null Mouse><Obesity><Pathogenesis><Pathogenicity><Pathway interactions><Patients><Persons><Physiopathology><Plasma><Plasma Serum><Platelet Transforming Growth Factor><Process><Production><Purine Receptors><Purinergic Receptors><Purinoceptor><Receptor Protein><Receptor Signaling><Regular Insulin><Reporting><Research><Residencies><Reticuloendothelial System, Serum, Plasma><Role><SLC12A3><SLC12A3 gene><Signal Induction><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Slow-Onset Diabetes Mellitus><Sodium Chloride><Solute Carrier Family 12 (Sodium/Chloride Transporter), Member 3><Source><Stable Diabetes Mellitus><Stimulus><Structure><T-Cell Activation><T-Cells><T-Lymphocyte><T2 DM><T2D><T2DM><T8 Cells><T8 Lymphocytes><TGF B><TGF-beta><TGF-beta Receptors><TGF-β><TGF-β Receptors><TGFbeta><TGFβ><TSC gene><TSC protein><Testing><Thiazide-Sensitive Sodium-Chloride Cotransporter><Thiazide-Sensitvie Na-Cl Cotransporter><Time><Tissues><Transforming Growth Factor beta><Transforming Growth Factor beta Receptors><Transforming Growth Factor β Receptors><Transforming Growth Factor-Beta Family Gene><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Wild Type Mouse><activate T cells><adiposity><adult onset diabetes><adulthood><aerobic glycolysis><attenuate><attenuates><autocrine><biological signal transduction><blood pressure elevation><cardiovascular disorder><cardiovascular function><cardiovascular risk><cardiovascular risk factor><circulatory system><co-morbid><co-morbidity><comorbidity><corpulence><cytokine><developmental><diabetes><diabetes mouse model><diabetes pathogenesis><diabetes risk><diabetic><driving><elevated blood pressure><experiment><experimental research><experimental study><experiments><extracellular><feeding><glucose metabolism><glucose uptake><heart disorder><high blood pressure><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><immune drugs><immune-based therapeutics><immunologic therapeutics><immunotherapeutics><immunotherapy agent><in vivo><increase in blood pressure><increased blood pressure><innovate><innovation><innovative><insight><interdisciplinary approach><ketosis resistant diabetes><lFN-Gamma><maturity onset diabetes><metabolic profile><mortality><mouse model><multidisciplinary approach><murine model><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathophysiology><pathway><prevent><preventing><public health relevance><receptor><renal><salt><salt hypertension><salt induced hypertension><salt sensitive hypertension><social role><sodium-chloride cotransporter><sodium-chloride transporter><thiazide-sensitive Na-Cl cotransporter><thiazide-sensitive cotransporter><thymus derived lymphocyte><type 2 DM><type II DM><type two diabetes><wildtype mouse>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jeffrey Lee Birk

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$716,507

FY 2026

Project Title

Psychological symptoms in healthcare workers following the COVID-19 pandemic and relationship to long-term cardiovascular risk

Grant Number:

5R01HL157341-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over the past year, the entire world has been upended by the COVID-19 pandemic. As of February 2021, there have been over 112 million confirmed cases and over 2.5 million deaths globally. In New York City, the initial US epicenter of the pandemic, there have been >700,000 cases, >89,000 hospitalizat...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bernard P. Chang

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$716,507

FY 2026

Project Title

Psychological symptoms in healthcare workers following the COVID-19 pandemic and relationship to long-term cardiovascular risk

Grant Number:

5R01HL157341-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over the past year, the entire world has been upended by the COVID-19 pandemic. As of February 2021, there have been over 112 million confirmed cases and over 2.5 million deaths globally. In New York City, the initial US epicenter of the pandemic, there have been >700,000 cases, >89,000 hospitalizat...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lydia Bazzano

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$708,607

FY 2026

Project Title

Early Life Cardiovascular Disease Risk Factors, Epigenetic Age Acceleration, and Alzheimer's Disease Related Brain Health

Grant Number:

5R01AG077000-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Dementia is a major global health challenge, and Alzheimer’s disease (AD) comprises 70% of dementia cases. Because AD has no effective treatment options, the Lancet Commission recently emphasized the critical need for effective, life-course prevention of AD. Epigenetic age acceleration (EAA...

Research Terms

<21+ years old><AD biological marker><AD biomarker><AD dementia><AD prevention><AD related biomarker><APOE><Active Follow-up><Adult><Adult Human><Affect><African American group><African American individual><African American people><African American population><African Americans><Age><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease prevention><Alzheimer prevention><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's biomarker><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease related biomarker><Alzheimer's related biomarker><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Apo-E><ApoE protein><Apolipoprotein E><Articulation><BMI><BMI percentile><BMI z-score><Biological><Blood Pressure><Body mass index><Brain><Brain Nervous System><Cardiac health><Cerebrovascular Circulation><Cerebrum><Childhood><Chronology><Clinical><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complex><D-Glucose><DNA Methylation><DNA methylation profiling><Data><Dementia><Dextrose><Disturbance in cognition><Encephalon><Functional MRI><Functional Magnetic Resonance Imaging><Glucose><Heart><Heart health><Impaired cognition><Investments><Knowledge><Life><Life Cycle><Life Cycle Stages><Link><Lipids><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methyl-Seq><MethylSeq><Methylation sequencing><Molecular><Molecular Fingerprinting><Molecular Profiling><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Neurobiology><Nuclear Magnetic Resonance Imaging><Participant><Pathology><Pathway interactions><Phenotype><Photons><Population><Precision Health><Predictive Factor><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Primary Senile Degenerative Dementia><Quetelet index><Race><Races><Renal function><Research><Research Resources><Resources><Risk Factors><Sampling><Scanning><Syndrome><Testing><Therapeutic><United States National Institutes of Health><Visit><White Matter Hyperintensity><Work><Zeugmatography><accelerated epigenetic age><accelerated epigenetic aging><accelerated pace of epigenetic aging><acceleration in epigenetic age><active followup><adulthood><ages><bi-racial><biologic><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biracial><blood flow in brain><brain MR imaging><brain MRI><brain blood circulation><brain blood flow><brain health><brain magnetic resonance imaging><cardiovascular disease risk><cardiovascular disorder risk><cerebral><cerebral MR imaging><cerebral MRI><cerebral blood flow><cerebral circulation><cerebral magnetic resonance imaging><cerebrocirculation><cerebrovascular blood flow><cognitive dysfunction><cognitive function><cognitive loss><cohort><cohort investigation><cohort research><drug development><effective therapy><effective treatment><fMRI><faster epigenetic aging><faster rates of epigenetic aging><follow up><follow-up><followed up><followup><genome scale><genome-wide><genomewide><global health><gray matter><improved><increased epigenetic age><increased epigenetic aging><increased rates of epigenetic aging><individualized prevention><insight><investigate cohort><kidney function><life course><mid life><mid-life><middle age><middle aged><midlife><molecular drug target><molecular pharmacotherapy target><molecular profile><molecular signature><neurobiological><neurocognitive test><neuropathologic><neuropathological><neuropathology><new approaches><novel><novel approaches><novel strategies><novel strategy><older adult><older adulthood><pathway><pediatric><personalized prevention><precision prevention><prevent><preventing><primary degenerative dementia><prospective><racial><racial background><racial origin><rapid epigenetic aging><risk stratification><senile dementia of the Alzheimer type><sex><stratify risk><study cohort><substantia grisea><survey cohort><tomography><waist circumference>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

OWEN T. CARMICHAEL

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$708,607

FY 2026

Project Title

Early Life Cardiovascular Disease Risk Factors, Epigenetic Age Acceleration, and Alzheimer's Disease Related Brain Health

Grant Number:

5R01AG077000-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Dementia is a major global health challenge, and Alzheimer’s disease (AD) comprises 70% of dementia cases. Because AD has no effective treatment options, the Lancet Commission recently emphasized the critical need for effective, life-course prevention of AD. Epigenetic age acceleration (EAA...

Research Terms

<21+ years old><AD biological marker><AD biomarker><AD dementia><AD prevention><AD related biomarker><APOE><Active Follow-up><Adult><Adult Human><Affect><African American group><African American individual><African American people><African American population><African Americans><Age><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease prevention><Alzheimer prevention><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's biomarker><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease related biomarker><Alzheimer's related biomarker><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Apo-E><ApoE protein><Apolipoprotein E><Articulation><BMI><BMI percentile><BMI z-score><Biological><Blood Pressure><Body mass index><Brain><Brain Nervous System><Cardiac health><Cerebrovascular Circulation><Cerebrum><Childhood><Chronology><Clinical><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complex><D-Glucose><DNA Methylation><DNA methylation profiling><Data><Dementia><Dextrose><Disturbance in cognition><Encephalon><Functional MRI><Functional Magnetic Resonance Imaging><Glucose><Heart><Heart health><Impaired cognition><Investments><Knowledge><Life><Life Cycle><Life Cycle Stages><Link><Lipids><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methyl-Seq><MethylSeq><Methylation sequencing><Molecular><Molecular Fingerprinting><Molecular Profiling><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Neurobiology><Nuclear Magnetic Resonance Imaging><Participant><Pathology><Pathway interactions><Phenotype><Photons><Population><Precision Health><Predictive Factor><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Primary Senile Degenerative Dementia><Quetelet index><Race><Races><Renal function><Research><Research Resources><Resources><Risk Factors><Sampling><Scanning><Syndrome><Testing><Therapeutic><United States National Institutes of Health><Visit><White Matter Hyperintensity><Work><Zeugmatography><accelerated epigenetic age><accelerated epigenetic aging><accelerated pace of epigenetic aging><acceleration in epigenetic age><active followup><adulthood><ages><bi-racial><biologic><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biracial><blood flow in brain><brain MR imaging><brain MRI><brain blood circulation><brain blood flow><brain health><brain magnetic resonance imaging><cardiovascular disease risk><cardiovascular disorder risk><cerebral><cerebral MR imaging><cerebral MRI><cerebral blood flow><cerebral circulation><cerebral magnetic resonance imaging><cerebrocirculation><cerebrovascular blood flow><cognitive dysfunction><cognitive function><cognitive loss><cohort><cohort investigation><cohort research><drug development><effective therapy><effective treatment><fMRI><faster epigenetic aging><faster rates of epigenetic aging><follow up><follow-up><followed up><followup><genome scale><genome-wide><genomewide><global health><gray matter><improved><increased epigenetic age><increased epigenetic aging><increased rates of epigenetic aging><individualized prevention><insight><investigate cohort><kidney function><life course><mid life><mid-life><middle age><middle aged><midlife><molecular drug target><molecular pharmacotherapy target><molecular profile><molecular signature><neurobiological><neurocognitive test><neuropathologic><neuropathological><neuropathology><new approaches><novel><novel approaches><novel strategies><novel strategy><older adult><older adulthood><pathway><pediatric><personalized prevention><precision prevention><prevent><preventing><primary degenerative dementia><prospective><racial><racial background><racial origin><rapid epigenetic aging><risk stratification><senile dementia of the Alzheimer type><sex><stratify risk><study cohort><substantia grisea><survey cohort><tomography><waist circumference>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tanika Nicole Kelly

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$708,607

FY 2026

Project Title

Early Life Cardiovascular Disease Risk Factors, Epigenetic Age Acceleration, and Alzheimer's Disease Related Brain Health

Grant Number:

5R01AG077000-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Dementia is a major global health challenge, and Alzheimer’s disease (AD) comprises 70% of dementia cases. Because AD has no effective treatment options, the Lancet Commission recently emphasized the critical need for effective, life-course prevention of AD. Epigenetic age acceleration (EAA...

Research Terms

<21+ years old><AD biological marker><AD biomarker><AD dementia><AD prevention><AD related biomarker><APOE><Active Follow-up><Adult><Adult Human><Affect><African American group><African American individual><African American people><African American population><African Americans><Age><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease prevention><Alzheimer prevention><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's biomarker><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease related biomarker><Alzheimer's related biomarker><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Apo-E><ApoE protein><Apolipoprotein E><Articulation><BMI><BMI percentile><BMI z-score><Biological><Blood Pressure><Body mass index><Brain><Brain Nervous System><Cardiac health><Cerebrovascular Circulation><Cerebrum><Childhood><Chronology><Clinical><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complex><D-Glucose><DNA Methylation><DNA methylation profiling><Data><Dementia><Dextrose><Disturbance in cognition><Encephalon><Functional MRI><Functional Magnetic Resonance Imaging><Glucose><Heart><Heart health><Impaired cognition><Investments><Knowledge><Life><Life Cycle><Life Cycle Stages><Link><Lipids><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methyl-Seq><MethylSeq><Methylation sequencing><Molecular><Molecular Fingerprinting><Molecular Profiling><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Neurobiology><Nuclear Magnetic Resonance Imaging><Participant><Pathology><Pathway interactions><Phenotype><Photons><Population><Precision Health><Predictive Factor><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Primary Senile Degenerative Dementia><Quetelet index><Race><Races><Renal function><Research><Research Resources><Resources><Risk Factors><Sampling><Scanning><Syndrome><Testing><Therapeutic><United States National Institutes of Health><Visit><White Matter Hyperintensity><Work><Zeugmatography><accelerated epigenetic age><accelerated epigenetic aging><accelerated pace of epigenetic aging><acceleration in epigenetic age><active followup><adulthood><ages><bi-racial><biologic><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biracial><blood flow in brain><brain MR imaging><brain MRI><brain blood circulation><brain blood flow><brain health><brain magnetic resonance imaging><cardiovascular disease risk><cardiovascular disorder risk><cerebral><cerebral MR imaging><cerebral MRI><cerebral blood flow><cerebral circulation><cerebral magnetic resonance imaging><cerebrocirculation><cerebrovascular blood flow><cognitive dysfunction><cognitive function><cognitive loss><cohort><cohort investigation><cohort research><drug development><effective therapy><effective treatment><fMRI><faster epigenetic aging><faster rates of epigenetic aging><follow up><follow-up><followed up><followup><genome scale><genome-wide><genomewide><global health><gray matter><improved><increased epigenetic age><increased epigenetic aging><increased rates of epigenetic aging><individualized prevention><insight><investigate cohort><kidney function><life course><mid life><mid-life><middle age><middle aged><midlife><molecular drug target><molecular pharmacotherapy target><molecular profile><molecular signature><neurobiological><neurocognitive test><neuropathologic><neuropathological><neuropathology><new approaches><novel><novel approaches><novel strategies><novel strategy><older adult><older adulthood><pathway><pediatric><personalized prevention><precision prevention><prevent><preventing><primary degenerative dementia><prospective><racial><racial background><racial origin><rapid epigenetic aging><risk stratification><senile dementia of the Alzheimer type><sex><stratify risk><study cohort><substantia grisea><survey cohort><tomography><waist circumference>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Chung Yin Kong

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$698,472

FY 2026

Project Title

Modeling Best Approaches for Cardiovascular Disease Prevention in Cancer Survivors

Grant Number:

5R01CA271604-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The overall goal of this proposal is to identify optimal strategies for primary prevention of cardiovascular disease (CVD) for survivors of breast (BC), prostate (PC) and lung (LC) cancer. All together, there are >6 million BC, PC and LC survivors in the US. While cancer is a major source of morbidi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jenny J. Lin

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$698,472

FY 2026

Project Title

Modeling Best Approaches for Cardiovascular Disease Prevention in Cancer Survivors

Grant Number:

5R01CA271604-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The overall goal of this proposal is to identify optimal strategies for primary prevention of cardiovascular disease (CVD) for survivors of breast (BC), prostate (PC) and lung (LC) cancer. All together, there are >6 million BC, PC and LC survivors in the US. While cancer is a major source of morbidi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JUAN P WISNIVESKY

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$698,472

FY 2026

Project Title

Modeling Best Approaches for Cardiovascular Disease Prevention in Cancer Survivors

Grant Number:

5R01CA271604-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The overall goal of this proposal is to identify optimal strategies for primary prevention of cardiovascular disease (CVD) for survivors of breast (BC), prostate (PC) and lung (LC) cancer. All together, there are >6 million BC, PC and LC survivors in the US. While cancer is a major source of morbidi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

YUQING Eugene CHEN

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$693,375

FY 2026

Project Title

Targeted editing of ASGR1 for cardiovascular diseases

Grant Number:

5R01HL169976-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT The contribution of low density lipoproteins (LDL) and very low density lipoproteins (VLDL) to the development of cardiovascular disease (CVD) is critical in atherogenesis. Recent therapeutic advances considerably reduced the incidence of CVD. Despite the progress of clinica...

Research Terms

<(hydroxymethylglutaryl-CoA reductase (NADPH)) kinase><5'-AMP-activated protein kinase><AAV vector><AAV-based vector><AMP-activated kinase><AMP-activated protein kinase><AMPK enzyme><ASCVD><ASGP-R><Address><Adopted><Animal Model><Animal Models and Related Studies><Animals><Asialoglycoprotein Receptor><Asialoglycoproteins><Asialoorosomucoid Receptor><Asialoorosomucoid-Binding Protein><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Blood Serum><CRISPR><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas system><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><CVD prevention><Cardiovascular Agents><Cardiovascular Diseases><Cardiovascular Drugs><Cardiovascular Models><Cas nuclease technology><Cause of Death><Cell Body><Cells><Cholesterol><Cholesterol Synthesis Inhibition><Clinical Treatment><Clinical Trials><Clustered Regularly Interspaced Short Palindromic Repeats><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><DNA><DNA Double Strand Break><DNA Therapy><Dangerousness><Deoxyribonucleic Acid><Desialylated Glycoproteins><Development><Diet><Domestic Rabbit><Dose><Drugs><Duchene><Duchenne><Duchenne muscular dystrophy><Duchenne-Griesinger syndrome><Dyslipidemias><Elements><Ellis-van Creveld (EvC) syndrome><Engineering><Event><Excretory function><FDA approved><Family suidae><Frequencies><Gametes><Gene Transfer Clinical><Generations><Genes><Genetic Intervention><Genetic study><Genome><Germ Cells><Germ-Line Cells><Glycoproteins><Guide RNA><Guidelines><HDL><HDL Cholesterol><HDL Cholesterol Lipoproteins><HDL Lipoproteins><HMG CoA reductase (NADPH) kinase><HMG CoA reductase kinase><HMG coenzyme A reductase (NADPH) kinase><Heavy Lipoproteins><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><High Density Lipoprotein Cholesterol><High Density Lipoproteins><Human><Human Genetics><Hyperlipemia><Hyperlipidemia><Immune response><In Vitro><Incidence><Innovative Therapy><Knowledge><LDL><LDL Cholesterol><LDL Cholesterol Lipoproteins><LDL Lipoproteins><Lesion><Light><Link><Lipids><Liver Cells><Low Density Lipoprotein Cholesterol><Low-Density Lipoproteins><Mediating><Medication><Methods><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><New Zealand><Nonsense Mutation><Oryctolagus cuniculus><Patients><Pharmaceutical Preparations><Photoradiation><Pigs><Point Mutation><Position><Positioning Attribute><Pre-Clinical Model><Prebeta-Lipoproteins><Preclinical Models><Proteins><Pseudohypertrophic Muscular Dystrophy><Rabbits><Rabbits Mammals><Recommendation><Recurrence><Recurrent><Reporting><Reproductive Cells><Research><Residual><Residual state><Ribonucleoproteins><Risk><Route><Running><Safety><Serum><Sex Cell><Suidae><Swine><Technology><Testing><Therapeutic><Therapeutic Gene Editing><Transcript><Treatment Efficacy><Triacylglycerol><Triglycerides><Tumorigenicity><VLDL><VLDL Lipoproteins><Very low density lipoprotein><Viral><Virus-like particle><X-linked dilated cardiomyopathy><X-linked muscular dystrophy><X-linked recessive muscular dystrophy><adeno-associated viral vector><adeno-associated virus vector><alpha-Lipoprotein Cholesterol><alpha-Lipoproteins><atherogenesis><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><atorvastatin><base editing><base editor><basolateral membrane><benign X-linked recessive muscular dystrophy><beta-Lipoprotein Cholesterol><beta-Lipoproteins><cardiac disease prevention><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disease therapy><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular disorder therapy><cardiovascular risk><cardiovascular risk factor><childhood pseudohypertrophic muscular dystrophy><classic X-linked recessive muscular dystrophy><clinical applicability><clinical application><clinical intervention><clinical relevance><clinical therapy><clinically relevant><curative intervention><curative therapeutic><curative therapy><curative treatments><determine efficacy><developmental><diets><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><excretion><experience><experiment><experimental research><experimental study><experiments><fat metabolism><gRNA><gene editing platform><gene editing system><gene editing technology><gene editing tools><gene repair therapy><gene therapy><gene-based therapy><gene-editing therapy><gene-editing toolkit><genetic therapy><genome editing><genome editing based therapy><genome editing therapy><genome editing treatment><genome editing-based therapeutics><genomic editing><genomic therapy><genotoxicity><host response><human disease><hydroxymethylglutaryl-CoA-reductase kinase><immune system response><immunoresponse><in vivo><inhibitor><initial cell><insight><intervention efficacy><knockout gene><lipid metabolism><lipitor><loss of function mutation><mild X-linked recessive muscular dystrophy><model of animal><mouse model><murine model><neuronal><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><non-sense mutation><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><particle><plasmid DNA><porcine><progressive muscular dystrophy of childhood><pseudohypertrophic adult muscular dystrophy><pseudohypertrophic muscular paralysis><safety engineering><sexual cell><spatial and temporal><spatial temporal><spatiotemporal><suid><therapeutic agent development><therapeutic development><therapeutic editing><therapeutic efficacy><therapeutic genome editing><therapeutic target><therapy efficacy><tool><translational study><trial regimen><trial treatment><uptake><virus-like nanoparticles><viruslike particle>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Renzhi Han

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$693,375

FY 2026

Project Title

Targeted editing of ASGR1 for cardiovascular diseases

Grant Number:

5R01HL169976-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT The contribution of low density lipoproteins (LDL) and very low density lipoproteins (VLDL) to the development of cardiovascular disease (CVD) is critical in atherogenesis. Recent therapeutic advances considerably reduced the incidence of CVD. Despite the progress of clinica...

Research Terms

<(hydroxymethylglutaryl-CoA reductase (NADPH)) kinase><5'-AMP-activated protein kinase><AAV vector><AAV-based vector><AMP-activated kinase><AMP-activated protein kinase><AMPK enzyme><ASCVD><ASGP-R><Address><Adopted><Animal Model><Animal Models and Related Studies><Animals><Asialoglycoprotein Receptor><Asialoglycoproteins><Asialoorosomucoid Receptor><Asialoorosomucoid-Binding Protein><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Blood Serum><CRISPR><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas system><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><CVD prevention><Cardiovascular Agents><Cardiovascular Diseases><Cardiovascular Drugs><Cardiovascular Models><Cas nuclease technology><Cause of Death><Cell Body><Cells><Cholesterol><Cholesterol Synthesis Inhibition><Clinical Treatment><Clinical Trials><Clustered Regularly Interspaced Short Palindromic Repeats><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><DNA><DNA Double Strand Break><DNA Therapy><Dangerousness><Deoxyribonucleic Acid><Desialylated Glycoproteins><Development><Diet><Domestic Rabbit><Dose><Drugs><Duchene><Duchenne><Duchenne muscular dystrophy><Duchenne-Griesinger syndrome><Dyslipidemias><Elements><Ellis-van Creveld (EvC) syndrome><Engineering><Event><Excretory function><FDA approved><Family suidae><Frequencies><Gametes><Gene Transfer Clinical><Generations><Genes><Genetic Intervention><Genetic study><Genome><Germ Cells><Germ-Line Cells><Glycoproteins><Guide RNA><Guidelines><HDL><HDL Cholesterol><HDL Cholesterol Lipoproteins><HDL Lipoproteins><HMG CoA reductase (NADPH) kinase><HMG CoA reductase kinase><HMG coenzyme A reductase (NADPH) kinase><Heavy Lipoproteins><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><High Density Lipoprotein Cholesterol><High Density Lipoproteins><Human><Human Genetics><Hyperlipemia><Hyperlipidemia><Immune response><In Vitro><Incidence><Innovative Therapy><Knowledge><LDL><LDL Cholesterol><LDL Cholesterol Lipoproteins><LDL Lipoproteins><Lesion><Light><Link><Lipids><Liver Cells><Low Density Lipoprotein Cholesterol><Low-Density Lipoproteins><Mediating><Medication><Methods><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><New Zealand><Nonsense Mutation><Oryctolagus cuniculus><Patients><Pharmaceutical Preparations><Photoradiation><Pigs><Point Mutation><Position><Positioning Attribute><Pre-Clinical Model><Prebeta-Lipoproteins><Preclinical Models><Proteins><Pseudohypertrophic Muscular Dystrophy><Rabbits><Rabbits Mammals><Recommendation><Recurrence><Recurrent><Reporting><Reproductive Cells><Research><Residual><Residual state><Ribonucleoproteins><Risk><Route><Running><Safety><Serum><Sex Cell><Suidae><Swine><Technology><Testing><Therapeutic><Therapeutic Gene Editing><Transcript><Treatment Efficacy><Triacylglycerol><Triglycerides><Tumorigenicity><VLDL><VLDL Lipoproteins><Very low density lipoprotein><Viral><Virus-like particle><X-linked dilated cardiomyopathy><X-linked muscular dystrophy><X-linked recessive muscular dystrophy><adeno-associated viral vector><adeno-associated virus vector><alpha-Lipoprotein Cholesterol><alpha-Lipoproteins><atherogenesis><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><atorvastatin><base editing><base editor><basolateral membrane><benign X-linked recessive muscular dystrophy><beta-Lipoprotein Cholesterol><beta-Lipoproteins><cardiac disease prevention><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disease therapy><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular disorder therapy><cardiovascular risk><cardiovascular risk factor><childhood pseudohypertrophic muscular dystrophy><classic X-linked recessive muscular dystrophy><clinical applicability><clinical application><clinical intervention><clinical relevance><clinical therapy><clinically relevant><curative intervention><curative therapeutic><curative therapy><curative treatments><determine efficacy><developmental><diets><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><excretion><experience><experiment><experimental research><experimental study><experiments><fat metabolism><gRNA><gene editing platform><gene editing system><gene editing technology><gene editing tools><gene repair therapy><gene therapy><gene-based therapy><gene-editing therapy><gene-editing toolkit><genetic therapy><genome editing><genome editing based therapy><genome editing therapy><genome editing treatment><genome editing-based therapeutics><genomic editing><genomic therapy><genotoxicity><host response><human disease><hydroxymethylglutaryl-CoA-reductase kinase><immune system response><immunoresponse><in vivo><inhibitor><initial cell><insight><intervention efficacy><knockout gene><lipid metabolism><lipitor><loss of function mutation><mild X-linked recessive muscular dystrophy><model of animal><mouse model><murine model><neuronal><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><non-sense mutation><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><particle><plasmid DNA><porcine><progressive muscular dystrophy of childhood><pseudohypertrophic adult muscular dystrophy><pseudohypertrophic muscular paralysis><safety engineering><sexual cell><spatial and temporal><spatial temporal><spatiotemporal><suid><therapeutic agent development><therapeutic development><therapeutic editing><therapeutic efficacy><therapeutic genome editing><therapeutic target><therapy efficacy><tool><translational study><trial regimen><trial treatment><uptake><virus-like nanoparticles><viruslike particle>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Duck-chul Lee

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$689,871

FY 2026

Project Title

Dose-response to resistance exercise on cardiovascular health

Grant Number:

5R01HL171098-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Cardiovascular disease (CVD) is the leading cause of death in the US and globally. Physical activity has been clearly shown to improve CVD risk factors and reduce disease incidence; thus, the US (and other countries) have guidelines for physical activity. Current guidelines ...

Research Terms

<(TNF)-α><21+ years old><ASCVD><Address><Adherence><Adult><Adult Human><Aerobic Activity><Aerobic Exercise><Aerobic Training><Aerobic fitness><Aorta><Arteries><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Attenuated><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Biological><Blood Pressure><Blood Vessels><Body Composition><Body fat><C-reactive protein><CVD prevention><Cachectin><Cardiovascular Diseases><Causality><Cause of Death><Chronic><Clinical Trials><Country><Data><Diet><Disease><Disorder><Dose><Environment><Etiology><Exercise><General Population><General Public><Guidelines><HPGF><Health><Health Benefit><Health Club><Hepatocyte-Stimulating Factor><Hybridoma Growth Factor><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Incidence><Inflammation><Interleukin-6><Intervention><Intervention Trial><Interventional trial><Jogging><Knowledge><LDL Cholesterol><LDL Cholesterol Lipoproteins><Link><Lipids><Low Density Lipoprotein Cholesterol><MGI-2><Macrophage-Derived TNF><Maintenance><Measurement><Measures><Meta-Analysis><Monocyte-Derived TNF><Myeloid Differentiation-Inducing Protein><Obesity><Observational Study><Overweight><Participant><Patient Self-Report><Persons><Phase><Physical activity><Plasmacytoma Growth Factor><Prescribed exercise><Property><Proteins, specific or class, C-reactive><Public Health Practice><Randomized><Randomized, Controlled Trials><Recommendation><Reporting><Research><Residual><Residual state><Risk><Risk Factors><Risk Reduction><Self-Report><Shapes><Smoking><Specific qualifier value><Specified><Structure><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Testing><Time><Translations><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Walking><Weight Lifting><adiposity><adulthood><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><attenuate><attenuates><beta-Lipoprotein Cholesterol><biologic><cardiac disease prevention><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular health><causation><corpulence><diets><disease causation><exercise prescription><exercise training><fasting glucose><glucose metabolism><improved><inflammation marker><inflammatory marker><interferon beta 2><life-style factor><lifestyle factors><observational research study><observational survey><primary outcome><randomisation><randomization><randomized control trial><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><resistance exercise><resistance training><response><risk-reducing><translation><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

I-Min Lee

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$689,871

FY 2026

Project Title

Dose-response to resistance exercise on cardiovascular health

Grant Number:

5R01HL171098-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Cardiovascular disease (CVD) is the leading cause of death in the US and globally. Physical activity has been clearly shown to improve CVD risk factors and reduce disease incidence; thus, the US (and other countries) have guidelines for physical activity. Current guidelines ...

Research Terms

<(TNF)-α><21+ years old><ASCVD><Address><Adherence><Adult><Adult Human><Aerobic Activity><Aerobic Exercise><Aerobic Training><Aerobic fitness><Aorta><Arteries><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Attenuated><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Biological><Blood Pressure><Blood Vessels><Body Composition><Body fat><C-reactive protein><CVD prevention><Cachectin><Cardiovascular Diseases><Causality><Cause of Death><Chronic><Clinical Trials><Country><Data><Diet><Disease><Disorder><Dose><Environment><Etiology><Exercise><General Population><General Public><Guidelines><HPGF><Health><Health Benefit><Health Club><Hepatocyte-Stimulating Factor><Hybridoma Growth Factor><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Incidence><Inflammation><Interleukin-6><Intervention><Intervention Trial><Interventional trial><Jogging><Knowledge><LDL Cholesterol><LDL Cholesterol Lipoproteins><Link><Lipids><Low Density Lipoprotein Cholesterol><MGI-2><Macrophage-Derived TNF><Maintenance><Measurement><Measures><Meta-Analysis><Monocyte-Derived TNF><Myeloid Differentiation-Inducing Protein><Obesity><Observational Study><Overweight><Participant><Patient Self-Report><Persons><Phase><Physical activity><Plasmacytoma Growth Factor><Prescribed exercise><Property><Proteins, specific or class, C-reactive><Public Health Practice><Randomized><Randomized, Controlled Trials><Recommendation><Reporting><Research><Residual><Residual state><Risk><Risk Factors><Risk Reduction><Self-Report><Shapes><Smoking><Specific qualifier value><Specified><Structure><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Testing><Time><Translations><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Walking><Weight Lifting><adiposity><adulthood><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><attenuate><attenuates><beta-Lipoprotein Cholesterol><biologic><cardiac disease prevention><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular health><causation><corpulence><diets><disease causation><exercise prescription><exercise training><fasting glucose><glucose metabolism><improved><inflammation marker><inflammatory marker><interferon beta 2><life-style factor><lifestyle factors><observational research study><observational survey><primary outcome><randomisation><randomization><randomized control trial><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><resistance exercise><resistance training><response><risk-reducing><translation><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ezra Burstein

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$686,687

FY 2026

Project Title

Cholesterol Regulation Through Retriever-Dependent LDL Receptor Recycling

Grant Number:

5R01HL179813-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Elevated plasma LDL cholesterol is a potent risk factor for atherosclerosis and cardiovascular complications. LDL is cleared from circulation by LDL receptors (LDLR). Importantly, the balance between internalization, recycling, and intracellular degradation of LDLR is critical in det...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Baoyu Chen

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$686,687

FY 2026

Project Title

Cholesterol Regulation Through Retriever-Dependent LDL Receptor Recycling

Grant Number:

5R01HL179813-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Elevated plasma LDL cholesterol is a potent risk factor for atherosclerosis and cardiovascular complications. LDL is cleared from circulation by LDL receptors (LDLR). Importantly, the balance between internalization, recycling, and intracellular degradation of LDLR is critical in det...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SATORU EGUCHI

UNIVERSITY OF SOUTH FLORIDA, TAMPA, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$682,570

FY 2026

Project Title

Vascular Pyruvate Kinase M2 in Hypertension

Grant Number:

5R01HL174004-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2024

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Hypertension is the most significant health burden for society in terms of economic and health costs due to the increased risk for cardiovascular disease (CVD) such as myocardial infarction and stroke. Patients with hypertension have significantly greater risks for cardiovascular mortality and morbi...

Research Terms

<ATP-protein phosphotransferase><Acceleration><Adenosine Cyclic Monophosphate-Dependent Protein Kinases><Affect><Age><AngII><Angiotensin AT1 Receptor><Angiotensin II><Angiotensin II Type 1 Receptor><Aorta><Apoplexy><Arteries><Attenuated><Autocrine Systems><Basic Research><Basic Science><Blood Pressure><Blood Vessels><Brain Vascular Accident><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Causality><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic><Communication><Complex><Cyclic AMP-Dependent Protein Kinases><Data><Development><Drug Therapy><Drugs><Dysfunction><Elements><Enzyme Gene><Enzymes><Etiology><Fibroblasts><Fibrosis><Functional disorder><Future><Glycolysis><Goals><Health><Health Care Costs><Health Costs><Heart Vascular><Hypertension><Impairment><In Vitro><Inflammation><Infusion><Infusion procedures><Intervention><Intracellular Communication and Signaling><Kinase Family Gene><Knowledge><Leiomyocyte><Link><Lycopersicon esculentum><Malignant Cell><Medial><Mediating><Medication><Mesenteric Arteries><Metabolic><Mice><Mice Mammals><Modeling><Molecular><Morbidity><Murine><Mus><Muscle Cell Contraction><Muscle Contraction><Muscular Contraction><Myocardial Infarct><Myocardial Infarction><Organ><PKA><Pathologic><Patients><Pharmaceutical Preparations><Pharmacological Treatment><Pharmacotherapy><Phenotype><Phenylephrine><Phosphorylation><Physiopathology><Play><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Protein Biosynthesis><Protein Kinase><Protein Kinase A><Protein Modification><Protein Phosphorylation><Publications><Publishing><Pyruvate Kinase><Receptor Protein><Receptor, Angiotensin, Type 1><Regulatory Pathway><Renin-Angiotensin System><Resistance><Ribosomal Peptide Biosynthesis><Ribosomal Protein Biosynthesis><Ribosomal Protein Synthesis><Risk><Risk Reduction><Rodent Model><Role><Sampling><Scientific Publication><Signal Transduction><Signal Transduction Systems><Signaling><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Societies><Solanum lycopersicum><Stroke><Testing><Tomatoes><Translational Research><Translational Science><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular Smooth Muscle><Vascular remodeling><Warburg Effect><aerobic glycolysis><ages><angiotensin II type I receptor><arterial remodeling><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><attenuate><attenuates><autocrine><biological signal transduction><blood pressure elevation><blood vessel disorder><brain attack><cAMP-Dependent Protein Kinases><cancer cell><cardiac infarct><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular function><cardiovascular risk><cardiovascular risk factor><causation><cell type><cerebral vascular accident><cerebrovascular accident><circulatory system><constriction><coronary attack><coronary infarct><coronary infarction><developmental><disability><disease causation><drug intervention><drug treatment><drug/agent><economic cost><elevated blood pressure><experiment><experimental research><experimental study><experiments><glucose metabolism><glycogen synthase a kinase><heart attack><heart infarct><heart infarction><high blood pressure><hydroxyalkyl protein kinase><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><increase in blood pressure><increased blood pressure><infusions><inhibitor><knock-down><knockdown><monomer><mortality><mouse model><murine model><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><normotensive><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><paracrine><pathophysiology><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><phosphoenol transphosphorylase><phosphoenolpyruvate kinase><phosphorylase b kinase kinase><protein synthesis><receptor><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><resistant><response><risk-reducing><social role><stroked><strokes><tool><translation research><translational investigation><vascular><vascular dysfunction><vasculopathy>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Patrick Osei-Owusu

UNIVERSITY OF SOUTH FLORIDA, TAMPA, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$682,570

FY 2026

Project Title

Vascular Pyruvate Kinase M2 in Hypertension

Grant Number:

5R01HL174004-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2024

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Hypertension is the most significant health burden for society in terms of economic and health costs due to the increased risk for cardiovascular disease (CVD) such as myocardial infarction and stroke. Patients with hypertension have significantly greater risks for cardiovascular mortality and morbi...

Research Terms

<ATP-protein phosphotransferase><Acceleration><Adenosine Cyclic Monophosphate-Dependent Protein Kinases><Affect><Age><AngII><Angiotensin AT1 Receptor><Angiotensin II><Angiotensin II Type 1 Receptor><Aorta><Apoplexy><Arteries><Attenuated><Autocrine Systems><Basic Research><Basic Science><Blood Pressure><Blood Vessels><Brain Vascular Accident><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Causality><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic><Communication><Complex><Cyclic AMP-Dependent Protein Kinases><Data><Development><Drug Therapy><Drugs><Dysfunction><Elements><Enzyme Gene><Enzymes><Etiology><Fibroblasts><Fibrosis><Functional disorder><Future><Glycolysis><Goals><Health><Health Care Costs><Health Costs><Heart Vascular><Hypertension><Impairment><In Vitro><Inflammation><Infusion><Infusion procedures><Intervention><Intracellular Communication and Signaling><Kinase Family Gene><Knowledge><Leiomyocyte><Link><Lycopersicon esculentum><Malignant Cell><Medial><Mediating><Medication><Mesenteric Arteries><Metabolic><Mice><Mice Mammals><Modeling><Molecular><Morbidity><Murine><Mus><Muscle Cell Contraction><Muscle Contraction><Muscular Contraction><Myocardial Infarct><Myocardial Infarction><Organ><PKA><Pathologic><Patients><Pharmaceutical Preparations><Pharmacological Treatment><Pharmacotherapy><Phenotype><Phenylephrine><Phosphorylation><Physiopathology><Play><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Protein Biosynthesis><Protein Kinase><Protein Kinase A><Protein Modification><Protein Phosphorylation><Publications><Publishing><Pyruvate Kinase><Receptor Protein><Receptor, Angiotensin, Type 1><Regulatory Pathway><Renin-Angiotensin System><Resistance><Ribosomal Peptide Biosynthesis><Ribosomal Protein Biosynthesis><Ribosomal Protein Synthesis><Risk><Risk Reduction><Rodent Model><Role><Sampling><Scientific Publication><Signal Transduction><Signal Transduction Systems><Signaling><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Societies><Solanum lycopersicum><Stroke><Testing><Tomatoes><Translational Research><Translational Science><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular Smooth Muscle><Vascular remodeling><Warburg Effect><aerobic glycolysis><ages><angiotensin II type I receptor><arterial remodeling><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><attenuate><attenuates><autocrine><biological signal transduction><blood pressure elevation><blood vessel disorder><brain attack><cAMP-Dependent Protein Kinases><cancer cell><cardiac infarct><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular function><cardiovascular risk><cardiovascular risk factor><causation><cell type><cerebral vascular accident><cerebrovascular accident><circulatory system><constriction><coronary attack><coronary infarct><coronary infarction><developmental><disability><disease causation><drug intervention><drug treatment><drug/agent><economic cost><elevated blood pressure><experiment><experimental research><experimental study><experiments><glucose metabolism><glycogen synthase a kinase><heart attack><heart infarct><heart infarction><high blood pressure><hydroxyalkyl protein kinase><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><increase in blood pressure><increased blood pressure><infusions><inhibitor><knock-down><knockdown><monomer><mortality><mouse model><murine model><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><normotensive><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><paracrine><pathophysiology><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><phosphoenol transphosphorylase><phosphoenolpyruvate kinase><phosphorylase b kinase kinase><protein synthesis><receptor><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><resistant><response><risk-reducing><social role><stroked><strokes><tool><translation research><translational investigation><vascular><vascular dysfunction><vasculopathy>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nathaniel D.M. Jenkins

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$673,456

FY 2026

Project Title

Interactions of Adverse Childhood Experiences, Sleep Disruption, and Mechanistic Links to Vascular Dysfunction in Emerging Adults

Grant Number:

5R01HL167788-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Adverse childhood experiences (ACEs), including abuse, neglect, household and community dysfunction, represent potentially traumatic psychosocial stressors that occur during critical development periods and represent a latent risk factor for future cardiovascular disease (CVD). ACE exposure...

Research Terms

<21+ years old><Adult><Adult Human><Adverse Experience><Adverse event><Affect><Anxiety><Apoplexy><Assay><Behavioral><Bioassay><Biological Assay><Biopsy><Blood Pressure><Blood Vessels><Brain Vascular Accident><CVD prevention><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Clinical><Cognition Therapy><Cognitive Psychotherapy><Cognitive Therapy><Cognitive treatment><Communities><Data><Delta Wave><Delta Wave sleep><Development><Dose><Dysfunction><Endothelial Cells><Endothelium><Exhibits><Exposure to><Functional disorder><Future><Goals><Heart Vascular><Home><Household><Human><Hybrids><Impairment><In Vitro><Individual><Inflammation><Insomnia><Insomnia Disorder><Intervention><Ischemic Heart><Ischemic Heart Disease><Ischemic myocardium><Life><Life Cycle><Life Cycle Stages><Link><Measures><Mediating><Mental Depression><Modern Man><Morbidity><Myocardial Ischemia><NIH><National Institutes of Health><Outcome Study><Oxidative Stress><Pathway interactions><Patient Self-Report><Physiopathology><Polysomnography><Prognostic Marker><Randomized><Reporting><Research><Risk><Risk Factors><Role><Self-Report><Sleep><Sleep Monitoring><Sleep disturbances><Sleeplessness><Slow-Wave Sleep><Somnography><Stroke><Testing><Therapeutic><United States National Institutes of Health><Vascular Diseases><Vascular Disorder><Vascular Endothelium><Wakefulness><Wrist><aberrant sleep><actigraph><actigraphy><adult youth><adulthood><adverse childhood events><adverse childhood experiences><behavioral sleep health intervention><behavioral sleep health program><behavioral sleep intervention><behavioral sleep strategies><behavioral sleep therapy><behavioral sleep treatment><biobehavior><biobehavioral><blood vessel disorder><brain attack><cardiac disease prevention><cardiac ischemia><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><cerebral vascular accident><cerebrovascular accident><circulatory system><cognitive behavior intervention><cognitive behavior modification><cognitive behavior therapy><cognitive behavioral intervention><cognitive behavioral modification><cognitive behavioral therapy><cognitive behavioral treatment><cohort><coronary ischemia><depression><developmental><disparity in health><disrupted sleep><disturbed sleep><early adulthood><early life stress><early onset><effective intervention><emerging adult><endothelial dysfunction><experience><fall asleep><health disparity><heart ischemia><homes><impaired sleep><improved><improvement on sleep><in vivo><innovate><innovation><innovative><irregular sleep><life course><mortality><myocardial ischemia/hypoxia><myocardium ischemia><neglect><novel><pathophysiology><pathway><poor sleep><pre-clinical><preclinical><prognostic><prognostic biomarker><prognostic indicator><psychosocial><psychosocial stresses><psychosocial stressors><quality of sleep><randomisation><randomization><randomly assigned><response><screening><screenings><sleep amount><sleep disruption><sleep duration><sleep dysregulation><sleep episode><sleep health><sleep hygiene><sleep improvement><sleep interval><sleep length><sleep measurement><sleep onset><sleep period><sleep polysomnography><sleep quality><sleep quantity><sleep time><sleep wellness><sleep/wake disruption><sleep/wake disturbance><social determinants><social role><sociodeterminant><stroked><strokes><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><traumatic event><vascular><vascular dysfunction><vascular endothelial dysfunction><vasculopathy><young adult><young adult age><young adulthood>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Shohreh F Farzan

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$669,373

FY 2026

Project Title

Children’s Cardiovascular Health and the Impacts of Heat Stress and Wildfire Smoke

Grant Number:

5R01ES036185-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/23/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over the last decade, the US has experienced extreme temperatures and heat events, while at the same time, wildfires continue to have devastating effects. As these trends continue across the US, the impacts of these exposures on children’s health remain largely unknown. Exposure to heat stress and w...

Research Terms

<0-11 years old><21+ years old><6 year old><6 years of age><Address><Adopted><Adult><Adult Human><Adverse effects><Air Conditioning><Air Pollution><BMI><BMI percentile><BMI z-score><Biological Markers><Blood Pressure><Body mass index><Buffers><Cardiac Chronotropism><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Child><Child Health><Child Youth><Childhood><Children (0-21)><Collection><Communities><Data><Development><Event><Exposure to><Filtration><Filtration Fractionation><Future><Gestation><Health><Health protection><Heart Rate><Heart Vascular><Heat Stress><Household><Individual><Intervention><Joints><Life><Life Cycle><Life Cycle Stages><Link><Los Angeles><Low Birth Weight Infant><Measures><Methods><Mothers><Outcome><Oxidative Stress><Pathway interactions><Pattern><Persons><Physiologic pulse><Population><Predisposition><Pregnancy><Premature Birth><Prematurely delivering><Preparedness><Preterm Birth><Prevention><Probabilistic Models><Probability Models><Prospective cohort><Pulse><Quetelet index><Readiness><Research><Rest><Risk><Risk Factors><Role><Schools><Smoke><Statistical Methods><Statistical Models><Susceptibility><Time><Trees><UNICEF><United States><Weather><Wildfire><Work><adulthood><age 6><age 6 years><air filtration><bio-markers><biologic marker><biomarker><blood lipid><blood pressure elevation><burden of disease><burden of illness><cardiovascular disorder><cardiovascular health><circulatory system><co-exposures><co-occurring exposure><combined exposure><community factor><community-level factor><complex exposure><concurrent exposure><cooling centers><cooling facilities><critical developmental period><critical period><determine efficacy><developmental><disease burden><effective intervention><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><elevated blood pressure><evaluate efficacy><examine efficacy><experience><exposed in utero><exposure mixture><extreme heat><extreme temperature><extreme weather><fetal exposure><hazard><heat island><improved><in utero exposure><increase in blood pressure><increased blood pressure><insight><intra-uterine environmental exposure><intrauterine environmental exposure><kids><life course><low birth weight><low birthweight><mixed exposure><mortality><novel><pathway><pediatric><premature childbirth><premature delivery><prenatal><prenatal exposure><prenatally exposed><preterm delivery><public health priorities><simultaneous exposures><six year old><six years of age><social role><statistic methods><statistical linear mixed models><statistical linear models><trend><unborn><urinary><wild fire><wildland fire><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rima Habre

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$669,373

FY 2026

Project Title

Children’s Cardiovascular Health and the Impacts of Heat Stress and Wildfire Smoke

Grant Number:

5R01ES036185-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/23/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over the last decade, the US has experienced extreme temperatures and heat events, while at the same time, wildfires continue to have devastating effects. As these trends continue across the US, the impacts of these exposures on children’s health remain largely unknown. Exposure to heat stress and w...

Research Terms

<0-11 years old><21+ years old><6 year old><6 years of age><Address><Adopted><Adult><Adult Human><Adverse effects><Air Conditioning><Air Pollution><BMI><BMI percentile><BMI z-score><Biological Markers><Blood Pressure><Body mass index><Buffers><Cardiac Chronotropism><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Child><Child Health><Child Youth><Childhood><Children (0-21)><Collection><Communities><Data><Development><Event><Exposure to><Filtration><Filtration Fractionation><Future><Gestation><Health><Health protection><Heart Rate><Heart Vascular><Heat Stress><Household><Individual><Intervention><Joints><Life><Life Cycle><Life Cycle Stages><Link><Los Angeles><Low Birth Weight Infant><Measures><Methods><Mothers><Outcome><Oxidative Stress><Pathway interactions><Pattern><Persons><Physiologic pulse><Population><Predisposition><Pregnancy><Premature Birth><Prematurely delivering><Preparedness><Preterm Birth><Prevention><Probabilistic Models><Probability Models><Prospective cohort><Pulse><Quetelet index><Readiness><Research><Rest><Risk><Risk Factors><Role><Schools><Smoke><Statistical Methods><Statistical Models><Susceptibility><Time><Trees><UNICEF><United States><Weather><Wildfire><Work><adulthood><age 6><age 6 years><air filtration><bio-markers><biologic marker><biomarker><blood lipid><blood pressure elevation><burden of disease><burden of illness><cardiovascular disorder><cardiovascular health><circulatory system><co-exposures><co-occurring exposure><combined exposure><community factor><community-level factor><complex exposure><concurrent exposure><cooling centers><cooling facilities><critical developmental period><critical period><determine efficacy><developmental><disease burden><effective intervention><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><elevated blood pressure><evaluate efficacy><examine efficacy><experience><exposed in utero><exposure mixture><extreme heat><extreme temperature><extreme weather><fetal exposure><hazard><heat island><improved><in utero exposure><increase in blood pressure><increased blood pressure><insight><intra-uterine environmental exposure><intrauterine environmental exposure><kids><life course><low birth weight><low birthweight><mixed exposure><mortality><novel><pathway><pediatric><premature childbirth><premature delivery><prenatal><prenatal exposure><prenatally exposed><preterm delivery><public health priorities><simultaneous exposures><six year old><six years of age><social role><statistic methods><statistical linear mixed models><statistical linear models><trend><unborn><urinary><wild fire><wildland fire><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LAURA A WOOLLETT

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$663,889

FY 2026

Project Title

Effect of reproductive history on longitudinal change in cardiac, vascular and lipid parameters

Grant Number:

5R01HL158100-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2021

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Pregnancy is often described as a physiologic “stress test” that may uncover latent risk for hypertension, diabetes and CVD. Even in uncomplicated pregnancies, women experience rapid cardiometabolic changes to support fetal development. While many of these adaptations normalize soon after d...

Research Terms

<10 year old><10 years of age><19 year old><19 years of age><20 year old><20 years of age><9 year old><9 years of age><ASCVD><Active Follow-up><African American><Afro American><Afroamerican><Age><Angiotensins><Apolipoproteins><Atherogenicity><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Birth><Blood Vessels><Blood Volume><Body Weight><CVD prevention><Cardiac><Cardiac Output><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular alteration><Cardiovascular system><Caucasian Females><Caucasian Women><Cause of Death><Cessation of life><Data><Death><Developing fetus><Development><Diabetes Mellitus><Echocardiogram><Echocardiography><Endocrine Physiology><Endothelium><Enrollment><Evaluation><Event><Exposure to><Female Health><Fetal Development><Generalized Growth><Generations><Gestation><Growth><HDL><HDL Cholesterol><HDL Cholesterol Lipoproteins><HDL Lipoproteins><Health><Heart Vascular><Heavy Lipoproteins><High Density Lipoprotein Cholesterol><High Density Lipoproteins><Hormonal><Hypertension><Intervention><LDL oxidation><LV Mass><Left Ventricular Mass><Life><Link><Lipids><Lipoproteins><Live Birth><Long-term cohort><Longitudinal cohort><Low Density Lipoprotein oxidation><Menopause><Myocardial depression><Myocardial dysfunction><NHLBI><National Heart, Lung, and Blood Institute><Nulliparas><Nulliparity><Nulliparous><Obesity><Obesity Epidemic><Onset of illness><Participant><Particle Size><Parturition><Pathway interactions><Perimenopausal><Perimenopause><Peripheral><Persons><Physiologic><Physiological><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Postpartum Period><Pre-Menopause><Pre-menopausal Period><Pregnancy><Premenopausal><Premenopausal Period><Premenopause><Prevalence><Proteins><Questionnaires><Relaxation><Reporting><Reproductive Factors><Reproductive History><Reproductive History Epidemiology><Reproductive Issues><Research><Risk><Risk Factors><Sampling><Socio-economic status><Socioeconomic Status><Stress Tests><Structure><Testing><Tissue Growth><Transthoracic Echocardiography><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular resistance><Ventricular><Visceral><Visit><White Females><White Women><Woman><Women's Health><Women's study><active followup><adiposity><after menopause><after pregnancy><age 10><age 10 years><age 19><age 19 years><age 20><age 20 years><age 9><age 9 years><ages><alpha-Lipoprotein Cholesterol><alpha-Lipoproteins><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><blood lipid><blood vessel disorder><cardiac disease prevention><cardiac dysfunction><cardiac function><cardiometabolic><cardiometabolism><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular health><cardiovascular imaging><cardiovascular risk><cardiovascular risk factor><circulatory system><cohort><corpulence><developmental><diabetes><disease onset><disorder onset><disparities affecting females><disparities affecting women><disparities among females><disparities among women><disparities facing women><disparities impacting women><disparities in females><disparities in race><disparities in women><disparity due to race><enroll><experience><female disparities><female study><follow up><follow-up><followed up><following menopause><followup><function of the heart><girls><heart dysfunction><heart function><heart output><heart sonography><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><indexing><inequality due to race><inequity due to race><insulin sensitivity/resistance><life span><lifespan><menopause transition><mid life><mid-life><middle age><middle aged><midlife><nine year old><nine years of age><nineteen year old><nineteen years old><older women><ontogeny><parity><particle><past menopause><pathway><peri-menopausal><peri-menopause><post pregnancy><post-menopausal><post-partum><postmenopausal><postmenopausal status><pre-clinical><pre-menopausal><preclinical><premenopausal status><prospective><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><reproductive><reproductive development><socio-economic position><socioeconomic position><study among females><study among women><study in females><study in women><study on females><study on women><study within women><ten year old><ten years of age><transition to menopause><transitional menopause><twenty year old><twenty years of age><vascular><vascular dysfunction><vasculopathy><women's disparities>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jessica G Woo

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$663,889

FY 2026

Project Title

Effect of reproductive history on longitudinal change in cardiac, vascular and lipid parameters

Grant Number:

5R01HL158100-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2021

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Pregnancy is often described as a physiologic “stress test” that may uncover latent risk for hypertension, diabetes and CVD. Even in uncomplicated pregnancies, women experience rapid cardiometabolic changes to support fetal development. While many of these adaptations normalize soon after d...

Research Terms

<10 year old><10 years of age><19 year old><19 years of age><20 year old><20 years of age><9 year old><9 years of age><ASCVD><Active Follow-up><African American><Afro American><Afroamerican><Age><Angiotensins><Apolipoproteins><Atherogenicity><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Birth><Blood Vessels><Blood Volume><Body Weight><CVD prevention><Cardiac><Cardiac Output><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular alteration><Cardiovascular system><Caucasian Females><Caucasian Women><Cause of Death><Cessation of life><Data><Death><Developing fetus><Development><Diabetes Mellitus><Echocardiogram><Echocardiography><Endocrine Physiology><Endothelium><Enrollment><Evaluation><Event><Exposure to><Female Health><Fetal Development><Generalized Growth><Generations><Gestation><Growth><HDL><HDL Cholesterol><HDL Cholesterol Lipoproteins><HDL Lipoproteins><Health><Heart Vascular><Heavy Lipoproteins><High Density Lipoprotein Cholesterol><High Density Lipoproteins><Hormonal><Hypertension><Intervention><LDL oxidation><LV Mass><Left Ventricular Mass><Life><Link><Lipids><Lipoproteins><Live Birth><Long-term cohort><Longitudinal cohort><Low Density Lipoprotein oxidation><Menopause><Myocardial depression><Myocardial dysfunction><NHLBI><National Heart, Lung, and Blood Institute><Nulliparas><Nulliparity><Nulliparous><Obesity><Obesity Epidemic><Onset of illness><Participant><Particle Size><Parturition><Pathway interactions><Perimenopausal><Perimenopause><Peripheral><Persons><Physiologic><Physiological><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Postpartum Period><Pre-Menopause><Pre-menopausal Period><Pregnancy><Premenopausal><Premenopausal Period><Premenopause><Prevalence><Proteins><Questionnaires><Relaxation><Reporting><Reproductive Factors><Reproductive History><Reproductive History Epidemiology><Reproductive Issues><Research><Risk><Risk Factors><Sampling><Socio-economic status><Socioeconomic Status><Stress Tests><Structure><Testing><Tissue Growth><Transthoracic Echocardiography><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular resistance><Ventricular><Visceral><Visit><White Females><White Women><Woman><Women's Health><Women's study><active followup><adiposity><after menopause><after pregnancy><age 10><age 10 years><age 19><age 19 years><age 20><age 20 years><age 9><age 9 years><ages><alpha-Lipoprotein Cholesterol><alpha-Lipoproteins><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><blood lipid><blood vessel disorder><cardiac disease prevention><cardiac dysfunction><cardiac function><cardiometabolic><cardiometabolism><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular health><cardiovascular imaging><cardiovascular risk><cardiovascular risk factor><circulatory system><cohort><corpulence><developmental><diabetes><disease onset><disorder onset><disparities affecting females><disparities affecting women><disparities among females><disparities among women><disparities facing women><disparities impacting women><disparities in females><disparities in race><disparities in women><disparity due to race><enroll><experience><female disparities><female study><follow up><follow-up><followed up><following menopause><followup><function of the heart><girls><heart dysfunction><heart function><heart output><heart sonography><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><indexing><inequality due to race><inequity due to race><insulin sensitivity/resistance><life span><lifespan><menopause transition><mid life><mid-life><middle age><middle aged><midlife><nine year old><nine years of age><nineteen year old><nineteen years old><older women><ontogeny><parity><particle><past menopause><pathway><peri-menopausal><peri-menopause><post pregnancy><post-menopausal><post-partum><postmenopausal><postmenopausal status><pre-clinical><pre-menopausal><preclinical><premenopausal status><prospective><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><reproductive><reproductive development><socio-economic position><socioeconomic position><study among females><study among women><study in females><study in women><study on females><study on women><study within women><ten year old><ten years of age><transition to menopause><transitional menopause><twenty year old><twenty years of age><vascular><vascular dysfunction><vasculopathy><women's disparities>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jaimie L. Gradus

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$659,928

FY 2026

Project Title

Evidence-based Treatment for PTSD and Cardiovascular Disease Risk

Grant Number:

5R01HL176899-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Posttraumatic stress disorder (PTSD) is an often chronic and disabling mental disorder that can have adverse consequences for health. Indeed, PTSD has been linked to heightened incidence of cardiovascular disease (CVD) and mortality. Fortunately, there are highly effective treatments...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Brian Shiner

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$659,928

FY 2026

Project Title

Evidence-based Treatment for PTSD and Cardiovascular Disease Risk

Grant Number:

5R01HL176899-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Posttraumatic stress disorder (PTSD) is an often chronic and disabling mental disorder that can have adverse consequences for health. Indeed, PTSD has been linked to heightened incidence of cardiovascular disease (CVD) and mortality. Fortunately, there are highly effective treatments...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jennifer A Sumner

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$659,928

FY 2026

Project Title

Evidence-based Treatment for PTSD and Cardiovascular Disease Risk

Grant Number:

5R01HL176899-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Posttraumatic stress disorder (PTSD) is an often chronic and disabling mental disorder that can have adverse consequences for health. Indeed, PTSD has been linked to heightened incidence of cardiovascular disease (CVD) and mortality. Fortunately, there are highly effective treatments...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jelena Levi

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$659,348

FY 2026

Project Title

[18F]F-AraG as an imaging biomarker for early diagnosis and monitoring of cardiotoxicity related to doxorubicin and immune check point inhibitor therapy

Grant Number:

5R01HL160688-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/21/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary (Abstract) Cardiovascular complications caused by cancer therapy are a major cause of morbidity and mortality in cancer patients and survivors. Cardiotoxicity of traditional cancer therapies, such as anthracyclines, as well as more selective, targeted therapies, have been well docume...

Research Terms

<14-Hydroxydaunomycin><18-FDG><18F- FDG><18FDG><2 Fluoro 2 deoxy D glucose><2-Fluoro-2-deoxyglucose><Address><Adriamycine><Animal Model><Animal Models and Related Studies><Anthracycline><Biological Markers><Blood><Blood Glucose><Blood Reticuloendothelial System><Blood Sugar><Body Tissues><Cancer Cause><Cancer Etiology><Cancer Patient><Cancer Survivor><Cancer Treatment><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Muscle Cells><Cardiac Myocytes><Cardiac Toxicity><Cardiocyte><Cardiotoxic><Cardiotoxicity><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cell Communication and Signaling><Cell Signaling><Cellular Immune Function><Checkpoint inhibitor><Clinical><Detection><Development><Diagnostic><Diet><Doxorubicin><Doxorubicina><Dysfunction><Early Diagnosis><Early identification><Evaluation><Functional disorder><Gender><Goals><Heart><Heart Diseases><Heart Injuries><Heart Muscle Cells><Heart Vascular><Heart failure><Heart myocyte><Hydroxyl Daunorubicin><Hydroxyldaunorubicin><Image><Imaging Procedures><Imaging Technics><Imaging Techniques><Immune checkpoint inhibitor><Immune infiltrates><Immune mediated therapy><Immunologically Directed Therapy><Immunotherapy><Impairment><Inflammatory><Intervention><Intracellular Communication and Signaling><LVEF><Left Ventricular Ejection Fraction><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Measurement><Mechanics><Mediating><Methods><Mitochondria><Molecular><Monitor><Morbidity><Muscle Cells><Myocardial><Myocardial depression><Myocardial dysfunction><Myocarditis><Myocytes><Non-Invasive Detection><Noninvasive Detection><Normal Range><Normal Values><Oncologist><Oncology><Oncology Cancer><PET><PET Scan><PET imaging><PETSCAN><PETT><Pathogenesis><Patients><Phase><Physiologic><Physiological><Physiopathology><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Prevention><Process><QOL improvement><Rad.-PET><Recommendation><Research><Signal Transduction><Signal Transduction Systems><Signaling><Specificity><T cell infiltration><T-Cell Activation><Techniques><Therapeutic Intervention><Tissues><TnI><Toxic effect><Toxicities><Troponin I><Visualization><activate T cells><age associated><age correlated><age dependent><age linked><age related><age specific><anti-cancer therapy><bio-markers><biologic marker><biological signal transduction><biomarker><cancer imaging><cancer therapy><cancer type><cancer-directed therapy><cardiac damage><cardiac dysfunction><cardiac failure><cardiac function><cardiac imaging><cardiac inflammation><cardiac injury><cardiac scanning><cardiomyocyte><cardiovascular risk><cardiovascular risk factor><check point immunotherapy><check point inhibitor therapy><check point inhibitory therapy><check point therapy><checkpoint immunotherapy><checkpoint inhibitor therapy><checkpoint inhibitory therapy><checkpoint therapy><chemotherapy><circulatory system><clinic ready><clinical ready><cohort><combinatorial><comparative><developmental><diagnostic approach><diagnostic strategy><diets><early detection><fluorodeoxyglucose><function of the heart><heart damage><heart disorder><heart dysfunction><heart function><heart imaging><heart scanning><human subject><image-based method><imaging><imaging approach><imaging based approach><imaging biomarker><imaging marker><imaging method><imaging modality><imaging-based biological marker><imaging-based biomarker><imaging-based marker><immune cell infiltrate><immune check point inhibitor><immune check point therapy><immune checkpoint therapy><immune function><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><improvements in QOL><improvements in quality of life><inhibitory troponin I><intervention therapy><kinase inhibitor><mechanic><mechanical><mitochondrial><model of animal><mortality><oncologic imaging><oncology imaging><pathophysiology><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><prevent><preventing><quality of life improvement><targeted agent><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><tool><tumor imaging><uptake>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Youngho Seo

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$659,348

FY 2026

Project Title

[18F]F-AraG as an imaging biomarker for early diagnosis and monitoring of cardiotoxicity related to doxorubicin and immune check point inhibitor therapy

Grant Number:

5R01HL160688-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/21/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary (Abstract) Cardiovascular complications caused by cancer therapy are a major cause of morbidity and mortality in cancer patients and survivors. Cardiotoxicity of traditional cancer therapies, such as anthracyclines, as well as more selective, targeted therapies, have been well docume...

Research Terms

<14-Hydroxydaunomycin><18-FDG><18F- FDG><18FDG><2 Fluoro 2 deoxy D glucose><2-Fluoro-2-deoxyglucose><Address><Adriamycine><Animal Model><Animal Models and Related Studies><Anthracycline><Biological Markers><Blood><Blood Glucose><Blood Reticuloendothelial System><Blood Sugar><Body Tissues><Cancer Cause><Cancer Etiology><Cancer Patient><Cancer Survivor><Cancer Treatment><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Muscle Cells><Cardiac Myocytes><Cardiac Toxicity><Cardiocyte><Cardiotoxic><Cardiotoxicity><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cell Communication and Signaling><Cell Signaling><Cellular Immune Function><Checkpoint inhibitor><Clinical><Detection><Development><Diagnostic><Diet><Doxorubicin><Doxorubicina><Dysfunction><Early Diagnosis><Early identification><Evaluation><Functional disorder><Gender><Goals><Heart><Heart Diseases><Heart Injuries><Heart Muscle Cells><Heart Vascular><Heart failure><Heart myocyte><Hydroxyl Daunorubicin><Hydroxyldaunorubicin><Image><Imaging Procedures><Imaging Technics><Imaging Techniques><Immune checkpoint inhibitor><Immune infiltrates><Immune mediated therapy><Immunologically Directed Therapy><Immunotherapy><Impairment><Inflammatory><Intervention><Intracellular Communication and Signaling><LVEF><Left Ventricular Ejection Fraction><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Measurement><Mechanics><Mediating><Methods><Mitochondria><Molecular><Monitor><Morbidity><Muscle Cells><Myocardial><Myocardial depression><Myocardial dysfunction><Myocarditis><Myocytes><Non-Invasive Detection><Noninvasive Detection><Normal Range><Normal Values><Oncologist><Oncology><Oncology Cancer><PET><PET Scan><PET imaging><PETSCAN><PETT><Pathogenesis><Patients><Phase><Physiologic><Physiological><Physiopathology><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Prevention><Process><QOL improvement><Rad.-PET><Recommendation><Research><Signal Transduction><Signal Transduction Systems><Signaling><Specificity><T cell infiltration><T-Cell Activation><Techniques><Therapeutic Intervention><Tissues><TnI><Toxic effect><Toxicities><Troponin I><Visualization><activate T cells><age associated><age correlated><age dependent><age linked><age related><age specific><anti-cancer therapy><bio-markers><biologic marker><biological signal transduction><biomarker><cancer imaging><cancer therapy><cancer type><cancer-directed therapy><cardiac damage><cardiac dysfunction><cardiac failure><cardiac function><cardiac imaging><cardiac inflammation><cardiac injury><cardiac scanning><cardiomyocyte><cardiovascular risk><cardiovascular risk factor><check point immunotherapy><check point inhibitor therapy><check point inhibitory therapy><check point therapy><checkpoint immunotherapy><checkpoint inhibitor therapy><checkpoint inhibitory therapy><checkpoint therapy><chemotherapy><circulatory system><clinic ready><clinical ready><cohort><combinatorial><comparative><developmental><diagnostic approach><diagnostic strategy><diets><early detection><fluorodeoxyglucose><function of the heart><heart damage><heart disorder><heart dysfunction><heart function><heart imaging><heart scanning><human subject><image-based method><imaging><imaging approach><imaging based approach><imaging biomarker><imaging marker><imaging method><imaging modality><imaging-based biological marker><imaging-based biomarker><imaging-based marker><immune cell infiltrate><immune check point inhibitor><immune check point therapy><immune checkpoint therapy><immune function><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><improvements in QOL><improvements in quality of life><inhibitory troponin I><intervention therapy><kinase inhibitor><mechanic><mechanical><mitochondrial><model of animal><mortality><oncologic imaging><oncology imaging><pathophysiology><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><prevent><preventing><quality of life improvement><targeted agent><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><tool><tumor imaging><uptake>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Noyan Gokce

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$654,934

FY 2026

Project Title

Identifying environmental pollutants detrimental to the cardiovascular system

Grant Number:

5R01HL173978-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract The current proposal represents a combined clinical and basic/molecular investigation which seeks to examine mechanisms of vascular dysfunction associated with persistent organic pollutants (POPs) and environmental toxicants that contribute to the pathogenesis of cardiovasc...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jennifer J Schlezinger

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$654,934

FY 2026

Project Title

Identifying environmental pollutants detrimental to the cardiovascular system

Grant Number:

5R01HL173978-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract The current proposal represents a combined clinical and basic/molecular investigation which seeks to examine mechanisms of vascular dysfunction associated with persistent organic pollutants (POPs) and environmental toxicants that contribute to the pathogenesis of cardiovasc...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jasimuddin Ahamed

OKLAHOMA MEDICAL RESEARCH FOUNDATION, OKLAHOMA CITY, OK

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$654,015

FY 2026

Project Title

Cardiovascular Risk of Antiretroviral Therapy Drugs in HIV

Grant Number:

5R01HL167656-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Although antiretroviral therapy drugs (ART) have prevented HIV propagation and increased life expectancy of people with HIV (PWH), the rate of sudden death in this population is 2-4-times higher than people without HIV. Autopsies have revealed cardiac fibrosis in half of this HIV pat...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sameed Ahmed Mustafa Khatana

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$651,308

FY 2026

Project Title

The impact of the Supplemental Nutrition Assistance Program on the cardiovascular health of low-income adults

Grant Number:

5R01HL171157-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Food insecurity—the economic and social condition of inconsistent access to healthy food—is associated with worse cardiovascular health. Whether food assistance related social policies can improve cardiovascular health among low-income adults in the US is unknown. The Supple...

Research Terms

<21+ years old><Acute><Address><Adult><Adult Human><American><Apoplexy><Assess implementation><Brain Vascular Accident><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Cardiac Failure Congestive><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Congestive Heart Failure><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Data><Data Bases><Databases><Diabetes Mellitus><Diagnostic><Disease><Disorder><ED visit><ER visit><Economic Conditions><Economical Conditions><Eligibility><Eligibility Determination><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Event><Food><Food Assistance Programs><Food Stamps><Funding><Generalized Growth><Government><Growth><Health><Health Benefit><Health Care Utilization><Health Expenditures><Health Food><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Health and Retirement Study><Heart Decompensation><Heart Vascular><Heart failure><High Prevalence><Hyperlipemia><Hyperlipidemia><Hypertension><Implementation assessment><Impoverished><Incidence><Individual><Interruption><Investments><Lead><Light><Link><Low Income Population><Low income><Low income group><Measures><Mediating><Medicaid><Medicare><Medicare/Medicaid><Myocardial Infarct><Myocardial Infarction><Nutritious food><Office Visits><Out-patients><Outcome><Outpatients><Participant><Pb element><Photoradiation><Policies><Policy Maker><Poverty><Prevalence><Protocol Screening><Psychosocial Stress><Public Health><Publishing><Recovery><Research><Risk Factors><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Schedule><Self Assessment><Series><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social Conditions><Social Policies><Societal Conditions><Source><Stroke><Supplemental Nutrition Assistance Program><Survey Instrument><Surveys><Techniques><Time><Tissue Growth><Title 18><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adulthood><alleviating poverty><atherosclerotic coronary disease><brain attack><cardiac failure><cardiac infarct><cardiovascular disorder><cardiovascular health><cardiovascular risk><cardiovascular risk factor><care utilization><cerebral vascular accident><cerebrovascular accident><chronic heart failure><circulatory system><coronary arterial disease><coronary attack><coronary infarct><coronary infarction><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><data base><diabetes><drug adherence><drug compliance><evaluate implementation><evaluation of implementation><experience><food insecure><food insecurity><food scarcity><food security><geographic disadvantage><geographic disparity><geographic inequality><geographic inequity><geographic location disparity><health assessment><health care expenditure><health care service use><health care service utilization><health insurance for disabled><healthy food><heart attack><heart infarct><heart infarction><heavy metal Pb><heavy metal lead><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation evaluation><improved><indexing><insight><low food security><low income individual><low income people><medical expenditure><medication adherence><medication compliance><older adult><older adulthood><ontogeny><outreach><physician office visit><poverty alleviation><poverty reduction><programs><reduce poverty><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social stigma><stigma><stroked><strokes>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

John Michael Stafford

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$647,763

FY 2026

Project Title

Sex-Specific Risk of Metabolic and Cardiovascular Disease

Grant Number:

7R01HL144846-07

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/15/2019

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Men are at higher risk of coronary heart disease (CHD) than age- and BMI-matched women, especially early in life when androgens are high. However, androgens are needed for health in men, particularly in muscle where they promote glucose metabolism and fatty acid utilization. Gap: we don’t know the m...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michelle L Bell

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$641,308

FY 2026

Project Title

Hospital admissions risks from fine particulate matter by source sector, fuel type, and components: A national analysis

Grant Number:

5R01ES036436-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/3/2025

End Date:

12/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT There is an urgent need to understand the health impacts of alternative air quality policies. Such policies can impact various source sectors (e.g., transportation), fuel type and chemical composition of fine particulate matter (PM2.5). Detailed characterization of the health consequences o...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Accounting><Address><Aerosols><Aged 65 and Over><Air Pollutants><Air Pollution><Asthma><Bronchial Asthma><Carbon Black><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cessation of life><Chemical Exposure><Chemicals><Code><Coding System><Data><Data Bases><Data Set><Databases><Death><Electricity><Ensure><Equipment and supply inventories><Exposure to><Generations><Goals><Health><Health Benefit><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Health Policy><Heart Vascular><Hospital Admission><Hospitalization><Human><Individual><Industry><Intervention><Inventory><Knowledge><Link><Liquid substance><Medicare><Medicare claim><Methodology><Methods><Modeling><Modern Man><Monitor><NO3-><National Academy of Sciences><Natural Gas><Neurologic><Neurological><Nitrates><Oils><Older Population><Outcome><PM2.5><Participant><Policies><Policy Maker><Policy Making><Pollution><Population Research><Population-based research><Population-level research><Public Health><Research><Resolution><Risk><Solid><Source><Sulfate><Survey Instrument><Surveys><Testing><Title 18><Transportation><Uncertainty><United States National Academy of Sciences><Validation><Work><above age 65><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><air monitoring><air quality><ambient air pollution><beneficiary><burden of disease><burden of illness><circulatory system><co-exposures><co-occurring exposure><combined exposure><complex exposure><concurrent exposure><cost effective><cost effective intervention><data base><data harmonization><disease burden><doubt><epidemiology research study><epidemiology study><epidemiology survey><exposure mixture><fine particles><fine particulate matter><flexibility><flexible><fluid><harmonized data><health assessment><health care policy><health insurance for disabled><human old age (65+)><innovate><innovation><innovative><investigate population><liquid><mixed exposure><nitrate><novel><older groups><older individuals><older person><outdoor air pollution><over 65 years><particle><pollutant><population investigation><population level investigation><population specific research><resolutions><respiratory><response><simultaneous exposures><spatial and temporal><spatial temporal><spatiotemporal><studies of populations><study of the population><study population><survey population><temporal measurement><temporal resolution><time measurement><validations><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jerica M Berge

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$634,951

FY 2026

Project Title

Examining How Psychosocial Stress Gets "Under the Skin" and Leads to Cardiovascular Disease Risk in Diverse Children: A Mixed-Methods Study

Grant Number:

5R01HL156994-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Recent reports from the American Journal of Public Health and the American Psychological Association identified a critical need to examine mechanisms by which exposure to psychosocial stress in childhood increases the risk for obesity and cardiovascular disease (CVD) in adulthood. Given the...

Research Terms

<0-11 years old><12-20 years old><13 year old><13 years of age><21+ years old><5 year old><5 years of age><6-11 years old><9 year old><9 years of age><Accelerometer><Active Follow-up><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Aeroseb-HC><Affect><African American><Afro American><Afroamerican><American><American Psychological Association><BMI><BMI percentile><BMI z-score><Behavioral><Biologic Factor><Biological><Biological Factors><Biological Markers><Blood Pressure><Body Composition><Body mass index><COVID-19><CV-19><Cardiac Chronotropism><Cardiovascular Diseases><Cetacort><Child><Child Behavior><Child Health><Child Rearing><Child Youth><Childhood><Children (0-21)><Cohort Studies><Coronavirus Infectious Disease 2019><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Data><Data Collection><Dermacort><Development><Dietary quality><Dimensions><Disadvantaged><Disease><Disorder><Disparities><Disparity><Ecological momentary assessment><Eldecort><Epidemiology><Ethnic Group><Ethnic Origin><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity><Ethnicity People><Ethnicity Population><Exposure to><Family><Family Life Cycle><Field Reports><Focus Groups><Frequencies><HPA axis><Hair><Heart Rate><Hispanic><Household><Hydrocortisone><Hydrocortone><Hytone><Immigrant><Individual><Individuals from minority><Individuals of minority><Interruption><Intervention><Investigators><Journals><Lead><Life Cycle><Life Cycle Stages><Magazine><Measures><Methods><Minority Groups><Minority People><Minority Population><Minority individual><NIH><National Institutes of Health><Native American><Neighborhoods><Nutracort><Obesity><Parenting><Parenting behavior><Parents><Pathway interactions><Pb element><Phase><Politics><Process><Proctocort><Psychosocial Stress><Puberty><Public Health><Quetelet index><Race><Races><Racial Group><Refugees><Reporting><Research Personnel><Researchers><Role><Severities><Skin><Stress><Structural Racism><Survey Instrument><Surveys><Time><United States National Institutes of Health><Weight><accelerometry><active followup><activity monitor><activity tracker><adiposity><adolescence (12-20)><adulthood><age 13><age 13 years><age 5><age 5 years><age 9><age 9 years><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><bio-markers><biologic><biologic marker><biomarker><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><child adiposity><child obesity><childhood adiposity><childhood obesity><childrearing><cohort research study><cohort survey><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><corpulence><design><designing><developmental><diet quality><dietary><disparities in race><disparity due to race><early experience><epidemiologic><epidemiological><ethnic subgroup><ethnicity group><experience><feeding><five year old><five years of age><follow up><follow-up><followed up><followup><heavy metal Pb><heavy metal lead><high risk><human centered design><hypothalamic-pituitary-adrenal (HPA) axis><hypothalamic-pituitary-adrenal axis><hypothalmus-pituitary-adrenal axis><improved><indexing><inequality due to race><inequity due to race><innovate><innovation><innovative><juvenile><juvenile human><kids><life course><middle childhood><nine year old><nine years of age><novel><obese children><obesity during childhood><obesity in children><obesity risk><parent><pathway><pediatric><pediatric obesity><prospective><psychosocial stresses><psychosocial stressors><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial><racial background><racial disparities in health><racial disparity><racial health disparity><racial inequality><racial inequity><racial origin><racial population><racial subgroup><racially unequal><resilience><resilient><retention rate><retention strategy><risk for obesity><risk mitigation><risk of obesity><social role><thirteen year old><thirteen years of age><waist circumference><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kevin James Cummings

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$634,861

FY 2026

Project Title

A critical forebrain-brainstem circuit contributes to the adaptive and maladaptive cardiorespiratory responses to hypoxia

Grant Number:

5R01HL176932-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Chronic intermittent Hx (CIH), a hallmark of obstructive sleep apnea and many other diseases, leads to a long- term increase in the strength of the peripheral chemoreflex (PCR). An enhanced PCR subsequently increases sympathetic nerve activity (SNA), leading to hypertension even in wakefulness, a ma...

Research Terms

<ACTH-Releasing Factor><Acute><Address><American><Apoplexy><Automobile Driving><Brain Stem><Brain Vascular Accident><Brainstem><CRF-41><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Carotid Body><Cell Nucleus><Central Alveolar Hypoventilation><Central Apnea><Central Sleep Apnea><Central Sleep Apnea Syndrome><Central Sleep-Disordered Breathing><Central Sleep-Disordered Breathings><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic><Corticoliberin><Corticotropin-Releasing Factor><Corticotropin-Releasing Factor-41><Corticotropin-Releasing Hormone><Corticotropin-Releasing Hormone-41><Data><Diestrus><Differences between sexes><Differs between sexes><Disease><Disorder><Estrogens><Female><Fore-Brain><Forebrain><Foundations><Genetic><Glomus Caroticum><Hcrt protein><Hcrt/ORX><Hcrts/ORXs><Health><Heart Vascular><Heart failure><Hypertension><Hypothalamic structure><Hypothalamus><Hypoxia><Hypoxic><In Vitro><Incidence><Modeling><Myocardial><Nerve><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Nucleus><Nucleus Tractus Solitarii><Nucleus solitarius><Obstructive Sleep Apnea><Ondine Syndrome><Oxygen Deficiency><Paraventricular Hypothalamic Nucleus><Patients><Peripheral><Phase><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Prosencephalon><Publishing><Reflex><Reflex action><Research><Role><Sex Differences><Sexual differences><Solitary Nucleus><Stroke><Sympathetic Nervous System><Syndrome, Sleep Apnea, Obstructive><Techniques><Testing><Therapeutic Estrogen><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Wakefulness><Woman><after menopause><brain attack><cardiac failure><cardiovascular disorder><cerebral vascular accident><cerebrovascular accident><circadian><circulatory system><corticotropin releasing hormone><driving><experience><female sex hormone><following menopause><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypocretin><hypocretin/orexin><hypocretins/orexins><hypothalamic><in vivo><insight><neural circuit><neural circuitry><neurocircuitry><neuronal><neuronal circuit><neuronal circuitry><novel><optogenetics><orexin><paraventricular nucleus><past menopause><post-menopausal><postmenopausal><postmenopausal status><response><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><solitary tract nucleus><stroked><strokes><synaptic circuit><synaptic circuitry><♀>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph Edward Tonna

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$632,485

FY 2026

Project Title

Physiology of Unloading VA ECMO Trial

Grant Number:

5R01HL168510-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/9/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Cardiogenic shock (CS) is a highly morbid condition (50% mortality) that occurs in 160,000 Americans each year, often as a complication of acute myocardial infarction. The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) is a promising therapy that can prov...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nikki Gillum Posnack

CHILDREN'S RESEARCH INSTITUTE, WASHINGTON, DC

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$629,045

FY 2026

Project Title

Off-label drugs in cardiology: evaluating age- and disease-appropriate therapies

Grant Number:

5R01HD108839-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Off-label medications are widely used in the clinical care of pediatric patients, with disproportionate use in cardiovascular subspecialties. More than 75% of children with cardiovascular disease receive at least one off- label medication. Further, congenital heart disease (CHD) pati...

Research Terms

<0-11 years old><21+ years old><Address><Adolescent><Adolescent Youth><Adrenaline><Adrenergic Agents><Adrenergic Drugs><Adrenergic Receptor><Adrenergic beta-Antagonists><Adrenergic beta-Blockers><Adrenergics><Adrenoceptors><Adult><Adult Human><Adverse effects><Affect><Age><Amiodarone><Anatomic Sites><Anatomic structures><Anatomy><Animal Model><Animal Models and Related Studies><Animals><Anti-Arrhythmia Agents><Anti-Arrhythmia Drugs><Anti-Arrhythmics><Architecture><Arrhythmia><Biophysics><Birth Defects><Body Tissues><Calcium><Cardiac><Cardiac Arrhythmia><Cardiac Malformation><Cardiac Muscle Cells><Cardiac Myocytes><Cardiac Output><Cardiac development><Cardiocyte><Cardiology><Cardiopulmonary Bypass><Cardiovascular><Cardiovascular Agents><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Drugs><Cardiovascular Organ System><Cardiovascular system><Child><Child Youth><Childhood><Children (0-21)><Clinical><Clinical Research><Clinical Study><Computer Models><Computerized Models><Congenital Abnormality><Congenital Anatomical Abnormality><Congenital Defects><Congenital Deformity><Congenital Malformation><Data><Depressed mood><Development><Disease><Disorder><Dopamine><Dose><Dropsy><Drug Design><Drug Prescribing><Drug Prescriptions><Drug Targeting><Drug Therapy><Drugs><Edema><Electrolytes><Electrophysiology><Electrophysiology (science)><Engineering / Architecture><Environment><Epinephrine><Epinephrine Receptors><Gene Transcription><Genetic Transcription><Goals><Heart><Heart Arrhythmias><Heart Malformation><Heart Muscle Cells><Heart Vascular><Heart failure><Heart myocyte><Heart-Lung Bypass><Human><Hydrops><Hydroxytyramine><Hypotension><Hypoxia><Hypoxic><Infant><Inflammation><Ion Channel><Ionic Channels><Knowledge><Lesion><Life><Live Birth><Low Blood Pressure><Low Cardiac Output><Maps><Math Models><Measurement><Mechanics><Medication><Membrane Channels><Metabolic><Methods><Mind><Modeling><Modern Man><Muscle><Muscle Tissue><Myocardial><Myocardium><Neonatal><Neurophysiology / Electrophysiology><Nodal><O element><O2 element><Operative Procedures><Operative Surgical Procedures><Optics><Outcome><Oxygen><Oxygen Deficiency><Patients><Pediatric cardiology><Pharmaceutical Preparations><Pharmacodynamics><Pharmacological Treatment><Pharmacotherapy><Physiology><Population><Postoperative><Postoperative Period><Process><Proteomics><RNA Expression><Regimen><Reporting><Safety><Surgical><Surgical Interventions><Surgical Procedure><System><Techniques><Testing><Therapeutic Epinephrine><Tissue Procurements><Tissues><Transcription><Underrepresented Groups><Underrepresented Populations><Vascular Hypotensive Disorder><Work><abnormal heart development><adenoreceptor><adulthood><age associated><age correlated><age dependent><age group><age linked><age related><age specific><ages><arrhythmic agent><beta blocker><beta-Adrenergic Blocking Agents><beta-Adrenergic Receptor Blockaders><biophysical foundation><biophysical principles><biophysical sciences><cardiac failure><cardiac muscle><cardiogenesis><cardiomyocyte><cardiovascular disorder><channel blockers><child patients><circulatory system><clinical care><computational modeling><computational models><computer based models><computerized modeling><congenital cardiac abnormality><congenital cardiac anomalies><congenital cardiac disease><congenital cardiac disorder><congenital cardiac malformation><congenital heart abnormality><congenital heart anomaly><congenital heart disease><congenital heart disorder><congenital heart malformation><depressed><developmental><drug detection><drug efficacy><drug intervention><drug testing><drug treatment><drug/agent><electrophysiological><esmolol><experience><fetal hypoxia><fetus hypoxia><heart bypass><heart development><heart formation><heart muscle><heart output><innovate><innovation><innovative><intervention design><juvenile><juvenile human><kids><mathematic model><mathematical model><mathematical modeling><mechanic><mechanical><medication prescription><model of animal><muscular><neonate><off-label><off-label drug><off-label medication><off-label prescription><optical><pediatric><pediatric patients><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><post-natal development><postnatal><postnatal development><pre-clinical study><preclinical study><prescribed medication><receptor density><repair><repaired><response><sadness><surgery><therapy design><transcriptomics><treatment design><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><voltage><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Guy M Genin

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 66/100

Training-friendly

Above-average budget

Very recent

Active award

$620,830

FY 2026

Project Title

Cardiovascular Innovation Program in Surgery & Engineering

Grant Number:

5T32HL170959-03

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT ABSTRACT Advanced studies in cardiovascular research innovation are increasingly requiring multi-disciplinary studies that include mathematical, computation, and engineering principles. Likewise, translation of novel discoveries requires clinical knowledge, and a solid foundation in the unde...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eric CLAUDE Leuthardt

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 66/100

Training-friendly

Above-average budget

Very recent

Active award

$620,830

FY 2026

Project Title

Cardiovascular Innovation Program in Surgery & Engineering

Grant Number:

5T32HL170959-03

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT ABSTRACT Advanced studies in cardiovascular research innovation are increasingly requiring multi-disciplinary studies that include mathematical, computation, and engineering principles. Likewise, translation of novel discoveries requires clinical knowledge, and a solid foundation in the unde...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mohamed A. Zayed

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 66/100

Training-friendly

Above-average budget

Very recent

Active award

$620,830

FY 2026

Project Title

Cardiovascular Innovation Program in Surgery & Engineering

Grant Number:

5T32HL170959-03

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT ABSTRACT Advanced studies in cardiovascular research innovation are increasingly requiring multi-disciplinary studies that include mathematical, computation, and engineering principles. Likewise, translation of novel discoveries requires clinical knowledge, and a solid foundation in the unde...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

COLIN SUMNERS

GEORGIA STATE UNIVERSITY, ATLANTA, GA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$620,326

FY 2026

Project Title

Angiotensin-sensitive neurons in the nucleus of the solitary tract mediate social stress induced hypertension

Grant Number:

5R01HL136595-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2017

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Despite therapeutic advances, ~20% of patients with hypertension have uncontrolled high blood pressure, a condition that is associated with dysfunction in brain cardiovascular control centers. Therefore, there is a critical need to understand the neural pathways involved in cardiovas...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Annette Diane de Kloet

GEORGIA STATE UNIVERSITY, ATLANTA, GA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$620,326

FY 2026

Project Title

Angiotensin-sensitive neurons in the nucleus of the solitary tract mediate social stress induced hypertension

Grant Number:

5R01HL136595-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2017

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Despite therapeutic advances, ~20% of patients with hypertension have uncontrolled high blood pressure, a condition that is associated with dysfunction in brain cardiovascular control centers. Therefore, there is a critical need to understand the neural pathways involved in cardiovas...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nicole Franziska Steinmetz

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$606,852

FY 2026

Project Title

Nanotechnology-based cardiovascular vaccines

Grant Number:

5R01HL175766-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

4Summary3 Cardiovascular disease (CVD) is the number one cause of death worldwide. The underlying cause is athero- sclerosis, which progresses to thrombosis and leads to myocardial infarction, stroke, and pulmonary embolism. The main drugs used for CVD management are statins and anti-coagulants, but...

Research Terms

<27E10 Antigen><ASCVD><Active Immunotherapy><Adjuvant><Age><Anti-Rejection Therapy><Antibodies><Antibody Response><Anticoagulant Agents><Anticoagulant Drugs><Anticoagulants><Antigenic Determinants><Apoplexy><Assay><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Attenuated><Binding><Binding Determinants><Bioassay><Biological Assay><Blood Serum><Brain Vascular Accident><CAGA><CAGB><CGCB><CGLA><Calcium-Binding Myeloid Protein P8,14><Calgranulin><Calprotectin><Cancer Patient><Cancer Treatment><Cancers><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Cell Body><Cell Function><Cell Physiology><Cell Process><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cholesterol><Cholesterol Homeostasis><Chronic><Clinical><Clinical Evaluation><Clinical Testing><Complex><Cowpea Mosaic Viruses><Data><Disease><Disease Management><Disorder><Disorder Management><Dose><Drug usage><Epitopes><Event><FDA approved><Female><Formulation><Health><Heart Vascular><Hemostasis><Hemostatic function><Human><Immune><Immune system><Immunes><Immunity><Immunization><Immunosuppressive Therapy><Immunotherapeutic agent><Implant><Induction Therapy><Inflammation><Inflammatory><KO mice><Knock-out><Knock-out Mice><Knockout><Knockout Mice><L1 Antigen><LIAG><Length of Life><Leukocyte L1 Antigen Complex><Leukocyte L1 Protein><Link><Longevity><Longitudinal Studies><Longitudinal Surveys><MA387><MAC387><MRP14><MRP8><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Mice><Mice Mammals><Migratory Inhibitory Factor-Related Protein MRP><Modeling><Modern Man><Molecular Interaction><Murine><Mus><Myeloid Cells><Myelomonocytic Antigen L1><Myocardial Infarct><Myocardial Infarction><NEOADJ><Nanotechnology><Neoadjuvant><Neoadjuvant Therapy><Neoadjuvant Treatment><Null Mouse><Organ><Passive Immunotherapy><Pathogenesis><Pathology><Patient Compliance><Patients><Pattern recognition receptor><Peptide Vaccines><Peptides><Plant Viruses><Preclinical Testing><Primary Prevention><Production><Proprotein Convertases><Proteins><Pulmonary Embolism><Recurrence><Recurrent><Relapse><Risk Reduction><Role><S100A8><S100A8 gene><S100A9><S100A9 gene><Safety><Sedentary behavior><Sedentary life-style><Serum><Stroke><Subcellular Process><Subtilisins><Testing><Therapeutic Intervention><Therapeutic immunosuppression><Thrombosis><Vaccination><Vaccines><Virus-like particle><age associated effects><age effect><age related effects><ages><aging effect><anti-cancer therapy><artificial immunosuppression><atheromatosis><atheroprotection><atheroprotective><atherosclerotic disease><atherosclerotic vascular disease><attenuate><attenuates><attenuation><blood thinner><brain attack><cancer therapy><cancer-directed therapy><cardiac infarct><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cerebral vascular accident><cerebrovascular accident><chemotherapy><cholesterol metabolism><chronic inflammatory disease><circadian><circulatory system><clinical test><coronary attack><coronary infarct><coronary infarction><cost><cowpea virus><cytokine><drug use><efficacy testing><heart attack><heart infarct><heart infarction><high risk><immune drugs><immune-based therapeutics><immunologic therapeutics><immunosuppression therapy><immunotherapeutics><immunotherapy agent><impact of age><induction therapies><influence of age><intervention therapy><life span><lifespan><long-term study><longitudinal outcome studies><longitudinal research study><male><malignancy><mouse model><murine model><nano particle><nano tech><nano technology><nano-sized particle><nano-technological><nanoparticle><nanosized particle><nanotech><nanotechnological><neoplasm/cancer><neoplastic><passive immune therapy><passive immunotherapeutics><patient adherence><patient cooperation><pre-clinical testing><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><research clinical testing><response><risk-reducing><sedentary lifestyle><sex><side effect><social role><stroked><strokes><thrombopoiesis inhibitor><thrombotic disease><thrombotic disorder><tumor><vaccine candidate><vaccine efficacy><vaccine safety><virus-like nanoparticles><viruslike particle><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sadiya Sana Khan

NORTHWESTERN UNIVERSITY AT CHICAGO, CHICAGO, IL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$597,946

FY 2026

Project Title

PRegnancy OuTcomEs and subclinical Cardiovascular disease sTudy: (PROTECT)

Grant Number:

5R01HL161514-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/6/2021

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT The goal of this proposal, PRegnancy OuTcomEs and subclinical Cardiovascular disease sTudy (PROTECT), is to understand the trajectory of risk factors and mechanisms linking interrelated adverse pregnancy outcomes (APOs) and subclinical cardiovascular disease (CVD). Hypertensive disorders of...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Benjamin A Garcia

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$597,424

FY 2026

Project Title

Development and Application of Chemical Biology Approaches for Understanding Protein Arginylation

Grant Number:

5R01HL177113-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/25/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project summary Posttranslational arginylation on proteins installed by arginyltransferase ATE1 is a critical modification for cardiovascular and heart development. The absence of this modification in ATE1 knockout mice was embryonically lethal with various signs of cardiovascular defects, emphasizi...

Research Terms

<21+ years old><55-kDa High-Affinity Calcium Binding Protein><Abscission><Actins><Adult><Adult Human><Amino Acids><Arginine><Assay><Bioassay><Biochemical><Biochemistry><Biological><Biological Assay><Biological Chemistry><Biological Function><Biological Process><Biology><Body Tissues><Body Weight decreased><CAB-63><CRISPR><CRISPR/Cas system><Calcium-Binding Protein-3><Calregulin><Cardiac><Cardiac Electrophysiologic Techniques><Cardiac Electrophysiological Diagnostics><Cardiac Myoblasts><Cardiac development><Cardiology><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cell Body><Cell Function><Cell Line><Cell Physiology><Cell Process><CellLine><Cells><Cellular Function><Cellular Matrix><Cellular Physiology><Cellular Process><Cessation of life><Chemicals><Chimera><Chimera organism><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats><Congestive Cardiomyopathy><Cytoskeletal System><Cytoskeleton><Data><Death><Defect><Development><Dilated Cardiomyopathy><Disease><Disorder><ERp60><Embryo><Embryonic><Enzyme Gene><Enzymes><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Esteroproteases><Excision><Extirpation><Genes><Genetic study><Goals><HACBP><Heart><Heart Vascular><Heart failure><High Throughput Assay><Histones><Homo><Investigation><Isotopes><KO mice><Knock-out><Knock-out Mice><Knockout><Knockout Mice><L-Arginine><LDL><LDL Lipoproteins><Low-Density Lipoproteins><Maps><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Metabolic Protein Degradation><Methods><Mice><Mice Mammals><Modality><Modification><Molecular><Molecular Configuration><Molecular Conformation><Molecular Stereochemistry><Murine><Mus><Myocardial Diseases><Myocardial Disorder><Myocardiopathies><NGS Method><NGS system><Neurology><Nucleosomes><Null Mouse><Organism-Level Process><Organismal Process><Patients><Peptidases><Peptide Hydrolases><Peptides><Physiologic Processes><Physiological Processes><Polymers><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Prevalence><Progenitor Cells><Protease Gene><Proteases><Protein Modification><Protein Turnover><Proteinases><Proteins><Proteolytic Enzymes><Proteome><Proteomics><Regulation><Regulatory Protein Degradation><Removal><Research><Role><Sampling><Site><Spermatogenesis><Strains Cell Lines><Subcellular Process><Surgical Removal><System><Techniques><Technology><Therapeutic><Time><Tissues><Validation><Weight Loss><Weight Reduction><adulthood><aminoacid><animal tissue><beta Actin><beta-Lipoproteins><biologic><body weight loss><cC1qR Protein><calreticulin><cardiac electrophysiology><cardiac failure><cardiogenesis><cardiomyoblasts><cardiovascular disorder><cardiovascular function><chimeras><circulatory system><conformation><conformational><conformational alteration><conformational state><conformationally><conformations><cultured cell line><developmental><entire genome><epigenetic regulation><epigenetically><full genome><heart development><heart electrophysiology><heart formation><high throughput screening><improved><innovate><innovation><innovative><insight><intracellular skeleton><myocardiac progenitor cells><myocardial precursors><myocardial progenitor><myocardial progenitor cells><myocardium disease><myocardium disorder><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutics><new therapy><new therapy approaches><new treatment approach><new treatment strategy><next gen sequencing><next generation sequencing><next generation therapeutics><nextgen sequencing><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutics><novel therapy><novel therapy approach><particle><polymer><polymeric><polymerization><protein degradation><protein function><resection><screening><screenings><social role><stem cells><validations><whole genome><wt-loss><β-Actin>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Zongtao Lin

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$597,424

FY 2026

Project Title

Development and Application of Chemical Biology Approaches for Understanding Protein Arginylation

Grant Number:

5R01HL177113-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/25/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project summary Posttranslational arginylation on proteins installed by arginyltransferase ATE1 is a critical modification for cardiovascular and heart development. The absence of this modification in ATE1 knockout mice was embryonically lethal with various signs of cardiovascular defects, emphasizi...

Research Terms

<21+ years old><55-kDa High-Affinity Calcium Binding Protein><Abscission><Actins><Adult><Adult Human><Amino Acids><Arginine><Assay><Bioassay><Biochemical><Biochemistry><Biological><Biological Assay><Biological Chemistry><Biological Function><Biological Process><Biology><Body Tissues><Body Weight decreased><CAB-63><CRISPR><CRISPR/Cas system><Calcium-Binding Protein-3><Calregulin><Cardiac><Cardiac Electrophysiologic Techniques><Cardiac Electrophysiological Diagnostics><Cardiac Myoblasts><Cardiac development><Cardiology><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cell Body><Cell Function><Cell Line><Cell Physiology><Cell Process><CellLine><Cells><Cellular Function><Cellular Matrix><Cellular Physiology><Cellular Process><Cessation of life><Chemicals><Chimera><Chimera organism><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats><Congestive Cardiomyopathy><Cytoskeletal System><Cytoskeleton><Data><Death><Defect><Development><Dilated Cardiomyopathy><Disease><Disorder><ERp60><Embryo><Embryonic><Enzyme Gene><Enzymes><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Esteroproteases><Excision><Extirpation><Genes><Genetic study><Goals><HACBP><Heart><Heart Vascular><Heart failure><High Throughput Assay><Histones><Homo><Investigation><Isotopes><KO mice><Knock-out><Knock-out Mice><Knockout><Knockout Mice><L-Arginine><LDL><LDL Lipoproteins><Low-Density Lipoproteins><Maps><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Metabolic Protein Degradation><Methods><Mice><Mice Mammals><Modality><Modification><Molecular><Molecular Configuration><Molecular Conformation><Molecular Stereochemistry><Murine><Mus><Myocardial Diseases><Myocardial Disorder><Myocardiopathies><NGS Method><NGS system><Neurology><Nucleosomes><Null Mouse><Organism-Level Process><Organismal Process><Patients><Peptidases><Peptide Hydrolases><Peptides><Physiologic Processes><Physiological Processes><Polymers><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Prevalence><Progenitor Cells><Protease Gene><Proteases><Protein Modification><Protein Turnover><Proteinases><Proteins><Proteolytic Enzymes><Proteome><Proteomics><Regulation><Regulatory Protein Degradation><Removal><Research><Role><Sampling><Site><Spermatogenesis><Strains Cell Lines><Subcellular Process><Surgical Removal><System><Techniques><Technology><Therapeutic><Time><Tissues><Validation><Weight Loss><Weight Reduction><adulthood><aminoacid><animal tissue><beta Actin><beta-Lipoproteins><biologic><body weight loss><cC1qR Protein><calreticulin><cardiac electrophysiology><cardiac failure><cardiogenesis><cardiomyoblasts><cardiovascular disorder><cardiovascular function><chimeras><circulatory system><conformation><conformational><conformational alteration><conformational state><conformationally><conformations><cultured cell line><developmental><entire genome><epigenetic regulation><epigenetically><full genome><heart development><heart electrophysiology><heart formation><high throughput screening><improved><innovate><innovation><innovative><insight><intracellular skeleton><myocardiac progenitor cells><myocardial precursors><myocardial progenitor><myocardial progenitor cells><myocardium disease><myocardium disorder><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutics><new therapy><new therapy approaches><new treatment approach><new treatment strategy><next gen sequencing><next generation sequencing><next generation therapeutics><nextgen sequencing><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutics><novel therapy><novel therapy approach><particle><polymer><polymeric><polymerization><protein degradation><protein function><resection><screening><screenings><social role><stem cells><validations><whole genome><wt-loss><β-Actin>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dongwen Lyu

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$597,424

FY 2026

Project Title

Development and Application of Chemical Biology Approaches for Understanding Protein Arginylation

Grant Number:

5R01HL177113-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/25/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project summary Posttranslational arginylation on proteins installed by arginyltransferase ATE1 is a critical modification for cardiovascular and heart development. The absence of this modification in ATE1 knockout mice was embryonically lethal with various signs of cardiovascular defects, emphasizi...

Research Terms

<21+ years old><55-kDa High-Affinity Calcium Binding Protein><Abscission><Actins><Adult><Adult Human><Amino Acids><Arginine><Assay><Bioassay><Biochemical><Biochemistry><Biological><Biological Assay><Biological Chemistry><Biological Function><Biological Process><Biology><Body Tissues><Body Weight decreased><CAB-63><CRISPR><CRISPR/Cas system><Calcium-Binding Protein-3><Calregulin><Cardiac><Cardiac Electrophysiologic Techniques><Cardiac Electrophysiological Diagnostics><Cardiac Myoblasts><Cardiac development><Cardiology><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cell Body><Cell Function><Cell Line><Cell Physiology><Cell Process><CellLine><Cells><Cellular Function><Cellular Matrix><Cellular Physiology><Cellular Process><Cessation of life><Chemicals><Chimera><Chimera organism><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats><Congestive Cardiomyopathy><Cytoskeletal System><Cytoskeleton><Data><Death><Defect><Development><Dilated Cardiomyopathy><Disease><Disorder><ERp60><Embryo><Embryonic><Enzyme Gene><Enzymes><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Esteroproteases><Excision><Extirpation><Genes><Genetic study><Goals><HACBP><Heart><Heart Vascular><Heart failure><High Throughput Assay><Histones><Homo><Investigation><Isotopes><KO mice><Knock-out><Knock-out Mice><Knockout><Knockout Mice><L-Arginine><LDL><LDL Lipoproteins><Low-Density Lipoproteins><Maps><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Metabolic Protein Degradation><Methods><Mice><Mice Mammals><Modality><Modification><Molecular><Molecular Configuration><Molecular Conformation><Molecular Stereochemistry><Murine><Mus><Myocardial Diseases><Myocardial Disorder><Myocardiopathies><NGS Method><NGS system><Neurology><Nucleosomes><Null Mouse><Organism-Level Process><Organismal Process><Patients><Peptidases><Peptide Hydrolases><Peptides><Physiologic Processes><Physiological Processes><Polymers><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Prevalence><Progenitor Cells><Protease Gene><Proteases><Protein Modification><Protein Turnover><Proteinases><Proteins><Proteolytic Enzymes><Proteome><Proteomics><Regulation><Regulatory Protein Degradation><Removal><Research><Role><Sampling><Site><Spermatogenesis><Strains Cell Lines><Subcellular Process><Surgical Removal><System><Techniques><Technology><Therapeutic><Time><Tissues><Validation><Weight Loss><Weight Reduction><adulthood><aminoacid><animal tissue><beta Actin><beta-Lipoproteins><biologic><body weight loss><cC1qR Protein><calreticulin><cardiac electrophysiology><cardiac failure><cardiogenesis><cardiomyoblasts><cardiovascular disorder><cardiovascular function><chimeras><circulatory system><conformation><conformational><conformational alteration><conformational state><conformationally><conformations><cultured cell line><developmental><entire genome><epigenetic regulation><epigenetically><full genome><heart development><heart electrophysiology><heart formation><high throughput screening><improved><innovate><innovation><innovative><insight><intracellular skeleton><myocardiac progenitor cells><myocardial precursors><myocardial progenitor><myocardial progenitor cells><myocardium disease><myocardium disorder><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutics><new therapy><new therapy approaches><new treatment approach><new treatment strategy><next gen sequencing><next generation sequencing><next generation therapeutics><nextgen sequencing><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutics><novel therapy><novel therapy approach><particle><polymer><polymeric><polymerization><protein degradation><protein function><resection><screening><screenings><social role><stem cells><validations><whole genome><wt-loss><β-Actin>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Brent Philip Myers

COLORADO STATE UNIVERSITY, FORT COLLINS, CO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$594,827

FY 2026

Project Title

Prefrontal-hypothalamic circuitry mediates chronic stress-induced cardiovascular susceptibility

Grant Number:

5R01HL173525-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary Cardiovascular disease is the leading cause of death worldwide and psychosocial stress is a significant predictor of disease incidence and severity. However, the specific neurobiological mechanisms that mediate the cardiovascular consequences of stress are largely unknown. Therefore, the cu...

Research Terms

<4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><Acute><Adrenal Glands><Adrenal Hormone><Adrenal hormone preparation><Adrenals><Affect><Affective Disorders><Aminalon><Aminalone><Baroreceptor Reflex><Baroreflex><Biological><Blood Pressure><Blood Vessels><Cardiac><Cardiac Chronotropism><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Nucleus><Cell Signaling><Cells><Chronic><Chronic stress><Clostridium tetani Toxin><Cognitive><Common Rat Strains><Data><Disease><Disorder><Disproportionate number of females><Disproportionate number of women><Disproportionately affects females><Disproportionately affects women><Disproportionately impacts females><Disproportionately impacts women><Disproportionately in females><Disproportionately in women><Dysfunction><Electrophysiology><Electrophysiology (science)><Emotions><Endocrine><Endocrine system><Endocrine/Metabolic Organ System><Female><Functional disorder><GABA><GABA Receptor><Gender Bias><Gene Expression><Glutamate Receptor><Glutamates><Goals><Heart Hypertrophy><Heart Rate><Heart Vascular><Hormonal System><Human><Hypophysis><Hypophysis Cerebri><Hypothalamic structure><Hypothalamus><Incidence><Intracellular Communication and Signaling><Investigation><L-Glutamate><Link><Measures><Medial><Mediating><Metabolic/Endocrine Body System><Modern Man><Mood Disorders><Myocardial depression><Myocardial dysfunction><Nerve Cells><Nerve Unit><Neural Cell><Neurobiology><Neurocyte><Neuroendocrine><Neuroendocrine System><Neurons><Neuropeptides><Neurophysiology / Electrophysiology><Neurosecretory Systems><Nucleus><Outcome><Output><Pathway interactions><Physiologic><Physiological><Physiology><Physiopathology><Pituitary><Pituitary Gland><Pituitary Nervous System><Population><Posterior Hypothalamic Region><Posterior Hypothalamus><Predisposition><Prefrontal Cortex><Process><Psychologic Stress><Psychological Stress><Psychosocial Stress><Rat><Rats Mammals><Rattus><Regulation><Risk Factors><Rodent><Rodentia><Rodents Mammals><Severities><Sex Bias><Signal Transduction><Signal Transduction Systems><Signaling><Slice><Stress><Structure><Susceptibility><Synapses><Synaptic><System><Telemetries><Telemetry><Testing><Tetanus Toxin><Translating><Vascular Diseases><Vascular Disorder><Viral><Visceral><Work><acute stress><biologic><biological adaptation to stress><biological signal transduction><blood vessel disorder><brain-body interaction><cardiac dysfunction><cardiac hypertrophy><cardiovascular disorder><cardiovascular health><cardiovascular risk><cardiovascular risk factor><circulatory system><combinatorial><disparity in health><electrophysiological><endocrine gland/system><experiment><experimental research><experimental study><experiments><female bias><female predominance><female preponderance><gamma-Aminobutyric Acid><gamma-Aminobutyric Acid Receptors><glutamate signaling><glutamatergic><glutamatergic dendrodendritic synapses><glutamatergic signaling><health disparity><heart dysfunction><hemodynamics><hypothalamic><in vivo><innervation><knock-down><knockdown><male><mind body interaction><mortality><nerve supply><neural><neurobiological><neurobiological mechanism><neuronal><neurotransmitter release><novel><optogenetics><patch clamp><pathophysiology><pathway><postsynaptic><predominance in females><predominance in women><prevent><preventing><reactioncrisis><response><sex><stress reactivity><stress response><stressreaction><suprarenal gland><synapse><telemetric><vascular><vascular dysfunction><vascular endothelial dysfunction><vasculopathy><women's predominance><women's preponderance><γ-Aminobutyric Acid><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KAMAL RAHMOUNI

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$585,994

FY 2026

Project Title

Role of FGF21 Action in Hypothalamic Neurons in Obesity-Associated Hypertension

Grant Number:

5R01HL162773-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary / Abstract Hypertension affects one billion people and is a principal reversible risk factor for cardiovascular disease. Obesity which has become common in the US and throughout the world is a major cause of hypertension, but the mechanisms underlying the relationship between obesity...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Terry D Hinds

UNIVERSITY OF MISSISSIPPI MED CTR, JACKSON, MS

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$579,247

FY 2026

Project Title

Novel liver-mediated mechanisms in hypertension and cardiac dysfunction

Grant Number:

5R01HL174521-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity and metabolic diseases such as type II diabetes are at an all-time high. The rates of nonalcoholic fatty liver disease (NAFLD) or recently renamed metabolic dysfunction-associated steatotic liver disease (MASLD) have dramatically increased to 25% of the population in the U.S. reflecting the ...

Research Terms

<3 Hydroxybutyrate><ASCVD><Address><Adult-Onset Diabetes Mellitus><Animals><Aorta><Assay><Atherosclerosis><Atherosclerotic Cardiovascular Disease><BDNF><BMI><BMI percentile><BMI z-score><BP reduction><Bioassay><Biological Assay><Blood><Blood Glucose><Blood Plasma><Blood Pressure><Blood Reticuloendothelial System><Blood Serum><Blood Sugar><Blood Vessels><Body mass index><Brain-Derived Neurotrophic Factor><Butanediols><Butylene Glycols><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cause of Death><Cell Communication and Signaling><Cell Signaling><Cessation of life><Chronic><Complication><D-Glucose><Data><Death><Dehydrogenases><Development><Dextrose><Diet><Dihydroxybutanes><Disease><Disorder><Dysfunction><Dyslipidemias><Endocrine Gland Secretion><Enzyme Gene><Enzymes><Excretory function><Exhibits><Fats><Fatty Liver><Fatty acid glycerol esters><Functional disorder><Gene Action Regulation><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><General Population><General Public><Glucose><Goals><Grant><Health Expenditures><Heart Vascular><Hepatic><Hepatic Cells><Hepatic Disorder><Hepatic Parenchymal Cell><Hepatocyte><Hormones><Human><Humulin R><Hypertension><Incidence><Infusion><Infusion procedures><Insulin><Insulin Resistance><Intracellular Communication and Signaling><Investigation><Ketones><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Urinary System><Kinases><L-Serine><Laboratories><Leanness><Left Ventricles><Left ventricular structure><Ligands><Link><Liver><Liver Cells><Liver Steatosis><Liver diseases><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Morbid Obesity><Morbidity><Murine><Mus><Myocardial depression><Myocardial dysfunction><NAFLD><NIDDM><Names><Nephropathy><Nerve Growth Factors><Neuronotrophic Factors><Neurotrophic Proteins><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Outcome><Oxidoreductase><Oxidoreductase Gene><PPAR alpha><PPAR-α><PPARalpha><PPARα><PTK Receptors><Pathway interactions><Patients><Peroxisome Proliferator-Activated Receptor alpha><Peroxisome Proliferator-Activated Receptor α><Phosphotransferase Gene><Phosphotransferases><Physiology><Physiopathology><Plasma><Plasma Serum><Population><Prevalence><Production><Protein-Serine Kinase><Protein-Serine-Threonine Kinases><Protein-Threonine Kinase><Proteins><Publishing><Quetelet index><Receptor Protein><Receptor Protein-Tyrosine Kinases><Receptor Tyrosine Kinase Gene><Recombinants><Reductases><Regular Insulin><Renal Disease><Research><Reticuloendothelial System, Serum, Plasma><Risk><Role><Running><SGLT 2 inhibitor><SGLT2i><Serine><Serine Kinase><Serine-Threonine Kinases><Serine/Threonine Protein Kinase Gene><Serum><Severe obesity><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Sodium glucose co-transporter 2 inhibitor><Source><Stable Diabetes Mellitus><Subgroup><Supplementation><T2 DM><T2D><T2DM><Techniques><Technology><Testing><Therapeutic Hormone><Thesaurismosis><Thinness><Threonine Kinase><Time><Transmembrane Receptor Protein Tyrosine Kinase><Transphosphorylases><Tropomyosin><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Tyrosine><Tyrosine Kinase Linked Receptors><Tyrosine Kinase Receptors><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><adiposity><adult onset diabetes><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><beta-Hydroxybutyrate><biological signal transduction><blood pressure reduction><cardiac dysfunction><cardiac function><cardiovascular disorder><cardiovascular function><chronic hepatic disease><chronic hepatic disorder><chronic liver disease><chronic liver disorder><circulatory system><corpulence><determine efficacy><developmental><diets><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><excretion><extreme obesity><fatty acid oxidation><function of the heart><health care expenditure><heart dysfunction><heart function><hepatic body system><hepatic disease><hepatic organ system><hepatic steatosis><hepatopathy><hepatosteatosis><high blood pressure><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><improved><infusions><insulin resistant><insulin tolerance><ketosis resistant diabetes><kidney disorder><liver disorder><lower BP><lower blood pressure><lowers blood pressure><maturity onset diabetes><medical expenditure><metabolism disorder><moderate obesity><name><named><naming><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><overexpress><overexpression><oxidation><pathophysiology><pathway><promoter><promotor><receptor><reduce BP><reduce blood pressure><reduction in BP><reduction in blood pressure><renal><renal disorder><restoration><social role><type 2 DM><type II DM><type two diabetes><vascular><β-Hydroxybutyrate>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DAVID E STEC

UNIVERSITY OF MISSISSIPPI MED CTR, JACKSON, MS

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$579,247

FY 2026

Project Title

Novel liver-mediated mechanisms in hypertension and cardiac dysfunction

Grant Number:

5R01HL174521-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity and metabolic diseases such as type II diabetes are at an all-time high. The rates of nonalcoholic fatty liver disease (NAFLD) or recently renamed metabolic dysfunction-associated steatotic liver disease (MASLD) have dramatically increased to 25% of the population in the U.S. reflecting the ...

Research Terms

<3 Hydroxybutyrate><ASCVD><Address><Adult-Onset Diabetes Mellitus><Animals><Aorta><Assay><Atherosclerosis><Atherosclerotic Cardiovascular Disease><BDNF><BMI><BMI percentile><BMI z-score><BP reduction><Bioassay><Biological Assay><Blood><Blood Glucose><Blood Plasma><Blood Pressure><Blood Reticuloendothelial System><Blood Serum><Blood Sugar><Blood Vessels><Body mass index><Brain-Derived Neurotrophic Factor><Butanediols><Butylene Glycols><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cause of Death><Cell Communication and Signaling><Cell Signaling><Cessation of life><Chronic><Complication><D-Glucose><Data><Death><Dehydrogenases><Development><Dextrose><Diet><Dihydroxybutanes><Disease><Disorder><Dysfunction><Dyslipidemias><Endocrine Gland Secretion><Enzyme Gene><Enzymes><Excretory function><Exhibits><Fats><Fatty Liver><Fatty acid glycerol esters><Functional disorder><Gene Action Regulation><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><General Population><General Public><Glucose><Goals><Grant><Health Expenditures><Heart Vascular><Hepatic><Hepatic Cells><Hepatic Disorder><Hepatic Parenchymal Cell><Hepatocyte><Hormones><Human><Humulin R><Hypertension><Incidence><Infusion><Infusion procedures><Insulin><Insulin Resistance><Intracellular Communication and Signaling><Investigation><Ketones><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Urinary System><Kinases><L-Serine><Laboratories><Leanness><Left Ventricles><Left ventricular structure><Ligands><Link><Liver><Liver Cells><Liver Steatosis><Liver diseases><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Morbid Obesity><Morbidity><Murine><Mus><Myocardial depression><Myocardial dysfunction><NAFLD><NIDDM><Names><Nephropathy><Nerve Growth Factors><Neuronotrophic Factors><Neurotrophic Proteins><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Outcome><Oxidoreductase><Oxidoreductase Gene><PPAR alpha><PPAR-α><PPARalpha><PPARα><PTK Receptors><Pathway interactions><Patients><Peroxisome Proliferator-Activated Receptor alpha><Peroxisome Proliferator-Activated Receptor α><Phosphotransferase Gene><Phosphotransferases><Physiology><Physiopathology><Plasma><Plasma Serum><Population><Prevalence><Production><Protein-Serine Kinase><Protein-Serine-Threonine Kinases><Protein-Threonine Kinase><Proteins><Publishing><Quetelet index><Receptor Protein><Receptor Protein-Tyrosine Kinases><Receptor Tyrosine Kinase Gene><Recombinants><Reductases><Regular Insulin><Renal Disease><Research><Reticuloendothelial System, Serum, Plasma><Risk><Role><Running><SGLT 2 inhibitor><SGLT2i><Serine><Serine Kinase><Serine-Threonine Kinases><Serine/Threonine Protein Kinase Gene><Serum><Severe obesity><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Sodium glucose co-transporter 2 inhibitor><Source><Stable Diabetes Mellitus><Subgroup><Supplementation><T2 DM><T2D><T2DM><Techniques><Technology><Testing><Therapeutic Hormone><Thesaurismosis><Thinness><Threonine Kinase><Time><Transmembrane Receptor Protein Tyrosine Kinase><Transphosphorylases><Tropomyosin><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Tyrosine><Tyrosine Kinase Linked Receptors><Tyrosine Kinase Receptors><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><adiposity><adult onset diabetes><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><beta-Hydroxybutyrate><biological signal transduction><blood pressure reduction><cardiac dysfunction><cardiac function><cardiovascular disorder><cardiovascular function><chronic hepatic disease><chronic hepatic disorder><chronic liver disease><chronic liver disorder><circulatory system><corpulence><determine efficacy><developmental><diets><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><excretion><extreme obesity><fatty acid oxidation><function of the heart><health care expenditure><heart dysfunction><heart function><hepatic body system><hepatic disease><hepatic organ system><hepatic steatosis><hepatopathy><hepatosteatosis><high blood pressure><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><improved><infusions><insulin resistant><insulin tolerance><ketosis resistant diabetes><kidney disorder><liver disorder><lower BP><lower blood pressure><lowers blood pressure><maturity onset diabetes><medical expenditure><metabolism disorder><moderate obesity><name><named><naming><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><overexpress><overexpression><oxidation><pathophysiology><pathway><promoter><promotor><receptor><reduce BP><reduce blood pressure><reduction in BP><reduction in blood pressure><renal><renal disorder><restoration><social role><type 2 DM><type II DM><type two diabetes><vascular><β-Hydroxybutyrate>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yu-Long Li

UNIVERSITY OF NEBRASKA MEDICAL CENTER, OMAHA, NE

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$573,159

FY 2026

Project Title

Potential mechanism underlying parasympathetic neuronal dysfunction in diabetes

Grant Number:

5R01HL168500-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Diabetes-induced imbalance of autonomic efferent neuronal tone (reduced parasympathetic activity and increased sympathetic activity) is involved in sudden cardiac death and is responsible for high mortality in diabetic patients. Increasing cardiovascular vagal tone significantly redu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marco Fazzari

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$562,908

FY 2026

Project Title

Nitro-nitrate fatty acid derivatives as novel cGMP-dependent and cGMP-independent signaling mediators

Grant Number:

5R01HL162787-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Organic nitrate esters are long-appreciated treatments for cardiovascular disease (CVD), leading causes of death worldwide. Of note, organic nitrates have never been detected biologically, and their vasodilatory effects are attenuated by the development of nitrate tolerance and endot...

Research Terms

<5-ISMN><Active Oxygen><Adhesion Molecule><Alkylation><Alternative Therapies><Alternative intervention><Anions><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Antioxidants><Attenuated><Binding><Biochemical><Blood Vessels><Carbon><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Cell Adhesion Molecule Gene><Cell Adhesion Molecules><Cell Communication and Signaling><Cell Growth in Number><Cell Multiplication><Cell Proliferation><Cell Signaling><Cellular Proliferation><Cessation of life><Charge><Chemicals><Chylomicrons><Circulation><Clinical><Clinical Data><Clinical Research><Clinical Study><Conjugated Linoleic Acids><Consumption><Cyclic GMP><Cysteine><D1S1733E><Dairy Products><Data><Death><Deoxyguanylate Cyclase><Development><Dietary Intervention><Digestion><Drug Kinetics><Drug Precursors><Drug Targeting><Electrons><Environment><Enzyme Gene><Enzymes><Esters><Fatty Acids><Ferroprotoporphyrin><Foundations><Fruit><Gene Expression><Generations><Genes><Glyceryl Trinitrate><Goals><Guanosine Cyclic Monophosphate><Guanyl Cyclase><Guanylate Cyclase><Half-Cystine><Healthy diet><Heart Vascular><Heme><Hemi-Myeloperoxidase><Hybrids><In Vitro><Incidence><Individual><Inflammation><Inflammatory><Inflammatory Response><Injury><Inosinate Cyclase><Intestinal Absorption><Intracellular Communication and Signaling><Ischemia><Isosorbide Mononitrate><L-Cysteine><MGC8972><Meat Products><Mediating><Mediator><Metabolic><Molecular Interaction><Myeloperoxidase><Myocardial><N03><NBL1><NBL1 gene><NO2><NO2-cLA><NO3><NO3-><Negative Beta Particle><Negatrons><Nitrates><Nitrites><Nitrogen Dioxide><Nitrogen Oxides><Nitrogen Peroxide><Nitroglycerin><Nutrition Interventions><Nutritional Interventions><Organic Synthesis><Outcome><Oxygen Radicals><Pathologic><Peroxidases><Pharmacokinetics><Pharmacology><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Preclinical data><Pro-Drugs><Pro-Oxidants><Prodrugs><Protein Modification><Protoheme><Reaction><Reactive Oxygen Species><Regulatory Protein><Reporting><Research><Route><Salivary><Signal Transduction><Signal Transduction Systems><Signaling><Source><Stomach><Stress><Testing><Transcription Regulatory Protein><Transcriptional Regulatory Protein><Triacylglycerol><Triglycerides><Unsaturated Fatty Acids><Vasodilatation><Vasodilation><Vasorelaxation><Vegetables><attenuate><attenuates><balanced diet><biological signal transduction><cGMP><cardiovascular disorder><cardiovascular effects><cell adhesion protein><circulatory system><cytokine><denitration><developmental><diet intervention><dietary><dietary constituent><dietary fruit><dietary vegetable><endothelial dysfunction><epidemiology research study><epidemiology study><epidemiology survey><ferroheme><gastric><gastrointestinal absorption><genetic regulatory protein><good diet><guanylyl cyclase><hypertensive><in vivo><injuries><insight><isosorbide-5-mononitrate><isosorbide-5-nitrate><lipid mediator><microbiome><mortality><new drug class><nitrate><nitrated conjugated linoleic acid><nitration><nitro-CLA><nitro-conjugated linoleic acid><nitroalkene><novel><novel drug class><pharmacologic><preclinical findings><preclinical information><regulatory gene product><response><stem><trinitrate 1,2,3-Propanetriol><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Orlando Paul Simonetti

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$549,267

FY 2026

Project Title

Development and validation of cardiovascular MRI techniques on a low-field, ultra-wide bore system to assess patients with severe obesity

Grant Number:

5R01HL161618-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract Obesity has reached epidemic proportions in the USA, with more than 40% of the population classified as obese (body mass index (BMI) > 30 kg/m2), and nearly 10% as severely obese (BMI > 40 kg/m2). Cardiovascular disease (CVD), especially heart failure, is highly associated w...

Research Terms

<21+ years old><Accuracy of Diagnosis><Address><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><American Heart Association><Apoplexy><Artifacts><BMI><BMI percentile><BMI z-score><Body mass index><Brain Vascular Accident><Breathing><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Diagnostic Technics><Cardiovascular Diagnostic Techniques><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cell Communication and Signaling><Cell Signaling><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Clinical Management><Compensation><Computed Tomography><Development><Diagnostic><Diagnostic Imaging><Diameter><Dyslipidemias><Echocardiogram><Echocardiography><Epidemic><Equipment><Face><Fatty Tissue><Functional impairment><General Radiology><Goals><Health Care><Heart Diseases><Heart Muscle tissue><Heart Vascular><Heart failure><Hispanic male><Hispanic men><Hypertension><Image><Image Enhancement><Incidence><Individual><Institution><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Link><MR Imaging><MR Tomography><MRI><MRI biomarker><MRI marker><MRIs><Machine Learning><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Modality><Morbid Obesity><Morphologic artifacts><Myocardial tissue><NIDDM><NMR Imaging><NMR Tomography><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Magnetic Resonance Imaging><Obesity><Obesity Epidemic><Outcome><Patients><Physiologic><Physiologic pulse><Physiological><Population><Prevalence><Prognosis><Protocol><Protocols documentation><Pulse><Quetelet index><Radiation><Radiation Dose><Radiation Dose Unit><Radiology><Radiology Specialty><Reference Standards><Reporting><Reproducibility><Respiratory Aspiration><Respiratory Inspiration><Risk><Risk Factors><SPECT><SPECT imaging><Safety><Scanning><Severe obesity><Severities><Signal Transduction><Signal Transduction Systems><Signaling><Single-Photon Emission-Computed Radionuclide Tomography><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><Structure><Symptoms><System><Systematics><T2 DM><T2D><T2DM><Techniques><Testing><Tomodensitometry><Transthoracic Echocardiography><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><Validation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Walking><Weight><Work><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><Zeugmatography><absorption><accurate diagnosis><adipose><adiposity><adult onset diabetes><adulthood><attenuation><biological signal transduction><biomedical implant><black female><black women><brain attack><cardiac MRI><cardiac failure><cardiac magnetic resonance imaging><cardiovascular disease diagnosis><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder diagnosis><cardiovascular disorder risk><cardiovascular imaging><catscan><cerebral vascular accident><cerebrovascular accident><circulatory system><clinical care><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><corpulence><data acquisition><data acquisitions><de-noising><death risk><denoising><design><designing><determine efficacy><developmental><diagnostic ability><diagnostic accuracy><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><experience><extreme obesity><faces><facial><flexibility><flexible><head-to-head analysis><head-to-head comparison><healthy volunteer><heart disorder><heart sonography><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><image construction><image generation><image reconstruction><image-based method><imaging><imaging method><imaging modality><imaging system><implant device><implantable device><indwelling device><innovate><innovation><innovative><inspiration><interest><ketosis resistant diabetes><life-time risk><lifetime risk><machine based learning><magnetic field><magnetic resonance imaging biomarker><magnetic resonance imaging marker><maturity onset diabetes><mortality risk><non-contrast CT><non-invasive imaging><noncontrast CT><noncontrast computed tomography><noninvasive imaging><novel><obese patients><patients with obesity><prognostic ability><prognostic power><prognostic utility><prognostic value><reconstruction><single photon emission computed tomography><statistics><stroked><strokes><tool><type 2 DM><type II DM><type two diabetes><ultrasound><validations><weights><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Sachs

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$537,702

FY 2026

Project Title

Microfluidic organoid model of cardio-hepatic physiology and disease

Grant Number:

5R01HL173456-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY As clinical trials have high failure rates, in part due to reliance on animal testing that can produce inaccurate results, accurate in vitro models of human physiology and disease are needed to bridge this gap. Recent progress in organoid and organ-on-chip systems demonstrates promising pote...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael J Daniels

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$531,474

FY 2026

Project Title

Bayesian machine learning for complex missing data and causal inference with a focus on cardiovascular and obesity studies

Grant Number:

5R01HL166324-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary This proposal will develop Bayesian machine learning approaches via Bayesian nonparametrics (BNP) to handle nonignorable missingness (in outcomes and covariates) and conduct causal inference for electronic health records (EHRs), to address missingness in multivariate longitudinal dat...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Xin-Yun Huang

WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$524,509

FY 2026

Project Title

Structural Dynamics and Regulatory Mechanisms of Atrial Natriuretic Peptide Receptor

Grant Number:

5R01HL177433-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2024

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Abstract Atrial natriuretic peptide (ANP) plays a pivotal role in cardiovascular homeostasis, produced by cardiomyocytes as a response to conditions like hypervolemia and hypertension. Its wide array of beneficial effects, including vasodilation, increased natriuresis, diuresis, and its anti...

Research Terms

<3,5 cyclic AMP synthetase><ANF Receptors><ANF receptor A><ANP Receptors><ANP-sensitive guanylyl cyclase><Active Sites><Address><Adenosine Cyclic Monophosphate-Dependent Protein Kinases><Adenyl Cyclase><Adenylate Cyclase><Adenylyl Cyclase><Animal Model><Animal Models and Related Studies><Antibodies><Architecture><Atrial Natriuretic Factor><Atrial Natriuretic Factor Receptors><Atrial Natriuretic Peptides><Atrial Natriuretic Peptides Receptors><Atriopeptin Receptors><Atriopeptins><Auriculin><Autoregulation><BNP Gene Product><BNP-32><BP reduction><Basic Research><Basic Science><Binding><Biochemical><Blood Vessels><Blood Volume><Brain Natriuretic Peptide-32><Brain natriuretic peptide><C-terminal><Cardiac Muscle Cells><Cardiac Myocytes><Cardiocyte><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Catalytic Core><Catalytic Domain><Catalytic Region><Catalytic Site><Catalytic Subunit><Cell Communication and Signaling><Cell Signaling><Clinical><Clinical Treatment><Complex><Cryo-electron Microscopy><Cryoelectron Microscopy><Cyclic AMP-Dependent Protein Kinases><Cyclic GMP><Deoxyguanylate Cyclase><Development><Diuresis><Electron Cryomicroscopy><Engineering / Architecture><Equilibrium><External Domain><Extracellular Domain><Fluid overload><G Protein-Coupled Receptor Signaling><G-Proteins><GPCR Signaling><GTP><GTP-Binding Proteins><GTP-Regulatory Proteins><Generations><Genes><Genetic study><Guanine Nucleotide Coupling Protein><Guanine Nucleotide Regulatory Proteins><Guanosine Cyclic Monophosphate><Guanosine Triphosphate><Guanyl Cyclase><Guanylate Cyclase><Heart><Heart Muscle Cells><Heart Vascular><Heart myocyte><Homeostasis><Hormone Receptor><Hypertension><Inosinate Cyclase><Intracellular Communication and Signaling><Intracellular Second Messenger><Investigation><Ion Channel><Ionic Channels><Kinases><Mediating><Membrane><Membrane Channels><Mice><Mice Mammals><Molecular><Molecular Configuration><Molecular Conformation><Molecular Dynamics Simulation><Molecular Interaction><Molecular Stereochemistry><Murine><Mus><Myocardial depression><Myocardial dysfunction><N-terminal><NH2-terminal><Natriuresis><Natriuretic Factor-32><Natriuretic Peptide Hormones><Natriuretic Peptides><Nature><Nesiritide><PKA><Peptide Hormone Gene><Peptide Receptor><Peptide Signal Sequences><Phosphodiesterases><Phosphotransferase Gene><Phosphotransferases><Physiologic><Physiological><Physiological Homeostasis><Play><Process><Protein Kinase A><Proteins><Public Health><Receptor Activation><Receptor Protein><Regulation><Regulatory Pathway><Research><Role><Second Messenger Systems><Second Messengers><Signal Peptide><Signal Sequences><Signal Transduction><Signal Transduction Systems><Signaling><Stress><Structure><Structure-Activity Relationship><Techniques><Therapeutic><Therapeutic Intervention><Transphosphorylases><Type-B Natriuretic Peptide><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vasodilatation><Vasodilation><Vasorelaxation><Work><atrial natriuretic factor receptor A><atrial natriuretic factor type A receptors><atrial natriuretic factor-R1><atrial natriuretic hormone><balance><balance function><biological signal transduction><blood pressure elevation><blood pressure reduction><blood vessel disorder><brain Natriuretic factor><cAMP-Dependent Protein Kinases><cGMP><cGMP production><cardiac dysfunction><cardiomyocyte><cardiovascular disorder><chemical structure function><circulatory system><clinical intervention><clinical therapy><conformation><conformational><conformational state><conformationally><conformations><cryo-EM><cryoEM><cryogenic electron microscopy><developmental><dimer><elevated blood pressure><functional status><guanyl cyclase-A receptor><guanylyl cyclase><guanylyl cyclase-A><guanylyl cyclase-A receptor><heart dysfunction><high blood pressure><hyperpiesia><hyperpiesis><hypertensive cardiomyopathy><hypertensive disease><hypertensive disorder><hypertensive heart disease><hypertensive heart disorder><hypervolemia><increase in blood pressure><increased blood pressure><inhibitor><insight><intervention therapy><kidney dysfunction><lower BP><lower blood pressure><lowers blood pressure><membrane structure><model of animal><molecular dynamics><mouse genetics><natriuretic peptide receptor 1><natriuretic peptide receptor A><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><peptide hormone><phosphoric diester hydrolase><polypeptide><programs><protein signal sequence><receptor><reduce BP><reduce blood pressure><reduction in BP><reduction in blood pressure><renal dysfunction><response><signal transduction second messengers><single molecule><social role><structure function relationship><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><trial regimen><trial treatment><vascular><vascular dysfunction><vasculopathy>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yanbo Fan

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$513,762

FY 2026

Project Title

CCDC92 and cardiovascular disease

Grant Number:

5R01HL167024-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Among patients with diabetes, cardiovascular diseases (CVDs) are the primary cause of their mortality. Reducing CVD risk is a critical clinical goal for treating diabetic patients. Diabetes exacerbates atherosclerosis development and progression, which is the major cause of many CVD, includ...

Research Terms

<4-3 Hydrophobic Repeat><ASCVD><Accounting><Adult-Onset Diabetes Mellitus><American><Animal Model><Animal Models and Related Studies><Aorta><Apoplexy><Apoptosis><Apoptosis Pathway><Arterial Fatty Streak><Atherogenicity><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Basal Transcription Factor><Basal transcription factor genes><Biogenesis><Biological Function><Biological Process><Blood Vessels><Brain Vascular Accident><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Function><Cell Isolation><Cell Physiology><Cell Process><Cell Segregation><Cell Separation><Cell Separation Technology><Cellular Function><Cellular Physiology><Cellular Process><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical><Code><Coding System><Coiled-Coil Domain><Coronary Disease><Coronary heart disease><Crossbreeding><D-Glucose><Data><Death><Development><Dextrose><Diabetes Mellitus><Disease><Disorder><Dysfunction><Epidemic><Event><Foundations><Functional disorder><Future><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genetic><Genetic Hybridization><Genetic Transcription><Genetic study><Glucose><Goals><Heart Vascular><High Fat Diet><Histologic><Histologically><Human><Human Biology><Impairment><In Vitro><Inflammation><Insulin Resistance><KI mice><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-in Mouse><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Left-Handed Twist><Leiomyocyte><Lysosomes><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Methods><Mice><Mice Mammals><Modern Man><Molecular><Morbidity><Murine><Mus><Myocardial Infarct><Myocardial Infarction><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Translocation><Null Mouse><Origin of Life><Pathogenesis><Pathologic><Pathway interactions><Patients><Peripheral Angiopathies><Peripheral Vascular Diseases><Peripheral Vascular Disorder><Phenotype><Physiopathology><Prevalence><Prevention><Programmed Cell Death><RNA Expression><Reporting><Research><Role><Slow-Onset Diabetes Mellitus><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Stable Diabetes Mellitus><Stimulus><Stroke><Subcellular Process><T2 DM><T2D><T2DM><Testing><Therapeutic><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Transgenic Mice><Transgenic Organisms><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><Vascular Smooth Muscle><adult onset diabetes><atherogenesis><atheromatosis><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic vascular disease><brain attack><cardiac infarct><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><cell sorting><cerebral vascular accident><cerebrovascular accident><circulatory system><clinical practice><clinical relevance><clinically relevant><coronary attack><coronary disorder><coronary infarct><coronary infarction><developmental><diabetes><diabetic><diabetic patient><euglycemia><experiment><experimental research><experimental study><experiments><genetically engineered cells><genetically modified cells><heart attack><heart infarct><heart infarction><human disease><in vivo><insulin resistant><insulin tolerance><ketosis resistant diabetes><knockin mice><maturity onset diabetes><model of animal><mortality><mouse model><murine model><new drug target><new druggable target><new pharmacotherapy target><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutic target><new therapy approaches><new therapy target><new treatment approach><new treatment strategy><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutic target><novel therapy approach><novel therapy target><overexpress><overexpression><pathophysiology><pathway><peripheral blood vessel disorder><plaques in atherosclerosis><protective effect><social role><statistics><stroked><strokes><transcription factor><transgenic><type 2 DM><type II DM><type two diabetes><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

BRANDON Scott Joseph DAVIES

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$501,095

FY 2026

Project Title

Regulation of Endothelial Lipase and HDL Metabolism by ANGPTL3

Grant Number:

5R01HL162698-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/13/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Despite currently available treatments, cardiovascular disease remains the leading cause of death in the United States. As dysregulated lipoprotein metabolism contribute to cardiovascular disease, there is a critical need to decipher the lipoprotein pathways, including those regulate...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Abby Fleisch

HARVARD PILGRIM HEALTH CARE, INC., Canton, MA

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$496,311

FY 2026

Project Title

Long-term prospective associations of PFAS with musculoskeletal and cardiovascular health among older adults

Grant Number:

5R01ES024765-09

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2015

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT ABSTRACT Per- and polyfluoroalkyl substances (PFAS) are persistent “forever chemicals” that contaminate water and food and are detectable in almost every individual in the US. Despite a manufacturer’s voluntary phase-out, efforts to limit production have been incomplete, and there is no US f...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Age Years><Aging><Angina at Rest><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Apoplexy><Assay><Attenuated><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Bioassay><Biological><Biological Assay><Blood Plasma><Brain Vascular Accident><Cardiac Failure Congestive><Cardiac infarction><Cardiovascular Diseases><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Chemicals><Cholesterol><Communities><Conditioning Therapy><Congestive Heart Failure><Coronary><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><DEXA><DXA><Data><Death><Diet><Dimethylbiguanidine><Dimethylguanylguanidine><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Endocrine Gland Secretion><Event><Exercise><Exposure to><Fats><Fatty acid glycerol esters><Food><Functional disorder><Funding><Grip strength><Grips><Hand><Hand Strength><Health><Healthy diet><Heart Decompensation><Hormonal Change><Hormones><Hospital Admission><Hospitalization><Individual><Industrialization><Inflammatory><Insulin Resistance><Intake><Intermediary Metabolism><Intervention><Legislation><Life><Life Style><Lifestyle><Long-term cohort><Long-term cohort study><Longitudinal cohort><Longitudinal cohort study><Manufacturer><Measures><Metabolic Processes><Metabolism><Metformin><Modeling><Modification><Muscle><Muscle Tissue><Musculoskeletal><Myocardial Infarct><Myocardial Infarction><N,N-dimethyl-imidodicarbonimidic diamide><N-3 polyunsaturated fatty acid><NIEHS><National Institute of Environmental Health Sciences><Omega-3 Fatty Acids><Omega-3 PUFA><Omega-3 Polyunsaturated Fatty Acid><Outcome><Outcome Study><PFAS><Participant><Peripheral><Phase><Physical activity><Physiopathology><Placebos><Plasma><Plasma Serum><Policies><Poly-fluoroalkyl substances><Population><Predisposition><Preinfarction Angina><Preventive><Production><Productivity><Public Policy><Randomization trial><Randomized><Reporting><Research Priority><Research Resources><Resources><Reticuloendothelial System, Serum, Plasma><Risk><Risk Reduction><Role><Sample Size><Scanning><Sham Treatment><Statistical Methods><Statutes and Laws><Strategic Planning><Stroke><Susceptibility><Testing><Therapeutic><Therapeutic Hormone><Unstable angina><Water contamination><Work><abdominal adiposity><abdominal fat><active followup><adjudication><adjudicative process and procedure><adulthood><age associated><age correlated><age dependent><age linked><age related><age specific><arm><atherosclerotic coronary disease><attenuate><attenuates><balanced diet><behavior intervention><behavioral intervention><biologic><bone mass><brain attack><cardiac infarct><cardiometabolic risk><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><cerebral vascular accident><cerebrovascular accident><chemical association><chronic heart failure><cohort><cohort investigation><cohort research><contaminated water><coronary arterial disease><coronary attack><coronary infarct><coronary infarction><cost><cytokine><decreased muscle mass><developmental toxicity><diabetes prevention program><diabetes risk><dietary><diets><ethnic diversity><ethnically diverse><follow up><follow-up><followed up><followup><good diet><grasp><hands><heart attack><heart infarct><heart infarction><improved><insulin resistant><insulin tolerance><investigate cohort><life style intervention><life-style factor><lifestyle factors><lifestyle intervention><low muscle mass><mid life><mid-life><middle age><middle aged><midlife><muscle bulk><muscle form><muscle mass><muscle strength><muscular><n-3 Fatty Acids><n-3 PUFA><novel><old age><older adult><older adulthood><omega-3><omega-3s><pathophysiology><perfluorinated alkyl substances><perfluoroalkyl substances><perfluoroalkylated substances><polyfluorinated alkyl substances><polyfluoroalkyl substances><post intervention><prospective><prospective test><racial diversity><racially diverse><randomisation><randomization><randomized trial><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduced muscle mass><reduces risk><reduces the risk><reducing risk><reducing the risk><revascularization><risk-reducing><sham therapy><social role><statistic methods><stroked><strokes><study cohort><survey cohort><water quality>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Emily Oken

HARVARD PILGRIM HEALTH CARE, INC., Canton, MA

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$496,311

FY 2026

Project Title

Long-term prospective associations of PFAS with musculoskeletal and cardiovascular health among older adults

Grant Number:

5R01ES024765-09

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2015

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT ABSTRACT Per- and polyfluoroalkyl substances (PFAS) are persistent “forever chemicals” that contaminate water and food and are detectable in almost every individual in the US. Despite a manufacturer’s voluntary phase-out, efforts to limit production have been incomplete, and there is no US f...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Age Years><Aging><Angina at Rest><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Apoplexy><Assay><Attenuated><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Bioassay><Biological><Biological Assay><Blood Plasma><Brain Vascular Accident><Cardiac Failure Congestive><Cardiac infarction><Cardiovascular Diseases><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Chemicals><Cholesterol><Communities><Conditioning Therapy><Congestive Heart Failure><Coronary><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><DEXA><DXA><Data><Death><Diet><Dimethylbiguanidine><Dimethylguanylguanidine><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Endocrine Gland Secretion><Event><Exercise><Exposure to><Fats><Fatty acid glycerol esters><Food><Functional disorder><Funding><Grip strength><Grips><Hand><Hand Strength><Health><Healthy diet><Heart Decompensation><Hormonal Change><Hormones><Hospital Admission><Hospitalization><Individual><Industrialization><Inflammatory><Insulin Resistance><Intake><Intermediary Metabolism><Intervention><Legislation><Life><Life Style><Lifestyle><Long-term cohort><Long-term cohort study><Longitudinal cohort><Longitudinal cohort study><Manufacturer><Measures><Metabolic Processes><Metabolism><Metformin><Modeling><Modification><Muscle><Muscle Tissue><Musculoskeletal><Myocardial Infarct><Myocardial Infarction><N,N-dimethyl-imidodicarbonimidic diamide><N-3 polyunsaturated fatty acid><NIEHS><National Institute of Environmental Health Sciences><Omega-3 Fatty Acids><Omega-3 PUFA><Omega-3 Polyunsaturated Fatty Acid><Outcome><Outcome Study><PFAS><Participant><Peripheral><Phase><Physical activity><Physiopathology><Placebos><Plasma><Plasma Serum><Policies><Poly-fluoroalkyl substances><Population><Predisposition><Preinfarction Angina><Preventive><Production><Productivity><Public Policy><Randomization trial><Randomized><Reporting><Research Priority><Research Resources><Resources><Reticuloendothelial System, Serum, Plasma><Risk><Risk Reduction><Role><Sample Size><Scanning><Sham Treatment><Statistical Methods><Statutes and Laws><Strategic Planning><Stroke><Susceptibility><Testing><Therapeutic><Therapeutic Hormone><Unstable angina><Water contamination><Work><abdominal adiposity><abdominal fat><active followup><adjudication><adjudicative process and procedure><adulthood><age associated><age correlated><age dependent><age linked><age related><age specific><arm><atherosclerotic coronary disease><attenuate><attenuates><balanced diet><behavior intervention><behavioral intervention><biologic><bone mass><brain attack><cardiac infarct><cardiometabolic risk><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><cerebral vascular accident><cerebrovascular accident><chemical association><chronic heart failure><cohort><cohort investigation><cohort research><contaminated water><coronary arterial disease><coronary attack><coronary infarct><coronary infarction><cost><cytokine><decreased muscle mass><developmental toxicity><diabetes prevention program><diabetes risk><dietary><diets><ethnic diversity><ethnically diverse><follow up><follow-up><followed up><followup><good diet><grasp><hands><heart attack><heart infarct><heart infarction><improved><insulin resistant><insulin tolerance><investigate cohort><life style intervention><life-style factor><lifestyle factors><lifestyle intervention><low muscle mass><mid life><mid-life><middle age><middle aged><midlife><muscle bulk><muscle form><muscle mass><muscle strength><muscular><n-3 Fatty Acids><n-3 PUFA><novel><old age><older adult><older adulthood><omega-3><omega-3s><pathophysiology><perfluorinated alkyl substances><perfluoroalkyl substances><perfluoroalkylated substances><polyfluorinated alkyl substances><polyfluoroalkyl substances><post intervention><prospective><prospective test><racial diversity><racially diverse><randomisation><randomization><randomized trial><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduced muscle mass><reduces risk><reduces the risk><reducing risk><reducing the risk><revascularization><risk-reducing><sham therapy><social role><statistic methods><stroked><strokes><study cohort><survey cohort><water quality>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael A HILL

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$484,616

FY 2026

Project Title

Epithelial sodium channels in endothelial cells and arterial stiffening

Grant Number:

5R01HL172875-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Epidemiological data have established an increased incidence of cardiovascular disease events in obese individuals, with these events being strongly associated with excessive arterial stiffness. Elevated aldosterone levels and activation of vascular mineralocorticoid recept...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Guanghong Jia

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$484,616

FY 2026

Project Title

Epithelial sodium channels in endothelial cells and arterial stiffening

Grant Number:

5R01HL172875-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Epidemiological data have established an increased incidence of cardiovascular disease events in obese individuals, with these events being strongly associated with excessive arterial stiffness. Elevated aldosterone levels and activation of vascular mineralocorticoid recept...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jingjing Zou

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$469,009

FY 2026

Project Title

Examining Longitudinal Changes in Accelerometer-Measured Physical Activity in Preventing Cardiovascular Disease with Novel Function Data Analysis Approaches

Grant Number:

5R01HL166802-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Physical activity (PA) has been linked to health in many epidemiological studies. Physical inactivity and sedentary behavior are known risk factors for cardiovascular disease (CVD), which is the leading cause of death in the United States with more than half a million deaths among older Americans an...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Francesca Luca

UNIVERSITY OF CHICAGO, CHICAGO, IL

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$456,223

FY 2026

Project Title

Functional genomics of GxE in cardiovascular disease: BPA, phthalates and their interactions with gene regulation

Grant Number:

5R01ES033634-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/12/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Cardiovascular disease is the leading global cause of death, accounting for more than 17.9 million deaths per year in 2015, a number that is expected to grow to more than 23.6 million by 2030. Several genetic and environmental factors contribute to cardiovascular disease risk. Bisphenol A ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Roger Pique-Regi

UNIVERSITY OF CHICAGO, CHICAGO, IL

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$456,223

FY 2026

Project Title

Functional genomics of GxE in cardiovascular disease: BPA, phthalates and their interactions with gene regulation

Grant Number:

5R01ES033634-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/12/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Cardiovascular disease is the leading global cause of death, accounting for more than 17.9 million deaths per year in 2015, a number that is expected to grow to more than 23.6 million by 2030. Several genetic and environmental factors contribute to cardiovascular disease risk. Bisphenol A ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Xiaoquan Wen

UNIVERSITY OF CHICAGO, CHICAGO, IL

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$456,223

FY 2026

Project Title

Functional genomics of GxE in cardiovascular disease: BPA, phthalates and their interactions with gene regulation

Grant Number:

5R01ES033634-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/12/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Cardiovascular disease is the leading global cause of death, accounting for more than 17.9 million deaths per year in 2015, a number that is expected to grow to more than 23.6 million by 2030. Several genetic and environmental factors contribute to cardiovascular disease risk. Bisphenol A ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Thomas E. Sharp

UNIVERSITY OF SOUTH FLORIDA, TAMPA, FL

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$400,850

FY 2026

Project Title

Alcohol-induced Gut Dysbiosis and Cardiovascular Disease

Grant Number:

5R01AA029984-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/8/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Hazardous alcohol use (HAU) leads to tremendous morbidity and mortality in millions of individuals in the United States and worldwide annually. The cognitive, neuronal, and psycho-social aspects of alcohol use have been well established. More recently, clinical, and basic research ha...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alexey Kamenskiy

UNIVERSITY OF NEBRASKA OMAHA, OMAHA, NE

Good lead · 62/100

Large award

Very recent

Active award

Team-scale grant

$2,206,298

FY 2026

Project Title

Center for Cardiovascular Research in Biomechanics

Grant Number:

5P20GM152301-03

Activity Code:

P20

Mechanism:

Research Centers

Agency:

NIH

Start Date:

2/15/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY – OVERALL We propose to establish the Center for Cardiovascular Research in Biomechanics (CRiB), which will provide a foundation for synergistic translational research activities aimed at developing novel materials and devices to treat cardiovascular diseases. To maximize impact, the...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Elizabeth Joanna Tarling

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$725,001

FY 2026

Project Title

Targeting the gut-liver axis in cardiovascular disease

Grant Number:

5R01HL163908-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Cardiovascular Disease (CVD) is the leading cause of death in the United States. Atherosclerosis is a hallmark of CVD and underlies many adverse events. Increased dietary lipid intake is a major contributor to the increased CVD disease burden. Elevated plasma lipids, particularly in the for...

Research Terms

<21+ years old><ASCVD><Acceleration><Acids><Adult><Adult Human><Adverse Experience><Adverse event><Affect><Assay><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Bacterial Toxins><Bile><Bile Acid Biosynthesis><Bile Acid Biosynthesis Pathway><Bile Acids><Bile Juice><Bile fluid><Bioassay><Biological Assay><Blood Plasma><CP7A><CRISPR><CRISPR/Cas system><CYP12><CYP2C><CYP2C19><CYP2C19 gene><CYP7A1><CYP7A1 gene><CYP8B1><CYP8B1 gene><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular Diseases><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chemical Structure><Chenic Acid><Chenique Acid><Chenodeoxycholic Acid><Chenodesoxycholic acid><Chenodiol><Cholalic Acids><Cholesterol><Cholesterol Esters><Cholesteryl Esters><Cholic Acids><Clustered Regularly Interspaced Short Palindromic Repeats><Communication><Cytochrome P450, Subfamily IIC, Polypeptide 19><Cytochrome P450, Subfamily VIIIB, Polypeptide 1><Detergents><Development><Diet><Dietary Fats><Dietary Fatty Acid><Disease><Disorder><Enzyme Gene><Enzymes><Fatty Acids><Gallodesoxycholic Acid><Gene Expression><Genes><Genetic study><Gut Epithelial Permeability><Gut Hyperpermeability><Gut permeability><Health system><Henohol><Hepatic><Human Genetics><Hypercholesteremia><Immune><Immunes><Inflammation><Inflammatory><Intake><Intermediary Metabolism><Intestinal><Intestinal Epithelial Permeability><Intestinal Hyperpermeability><Intestinal Leakage><Intestinal permeability><Intestines><Intracellular Communication and Signaling><LDL><LDL Cholesterol><LDL Cholesterol Lipoproteins><LDL Lipoproteins><Leaky Gut><Lipids><Liver><Low Density Lipoprotein Cholesterol><Low-Density Lipoproteins><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measures><Mediating><Mephenytoin 4-Prime Hydroxylase><Metabolic Processes><Metabolism><Mice><Mice Mammals><Murine><Mus><Nutrient><P450C2C><Pathogenesis><Pathway interactions><Plasma><Plasma Serum><Property><Public Health><RNA Seq><RNA sequencing><RNAseq><Reticuloendothelial System, Serum, Plasma><Role><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Sterol 12-alpha-Hydroxylase><System><Testing><Therapeutic><Therapeutic Intervention><Triacylglycerol><Triglycerides><United States><Zetia><absorption><adulthood><atheromatosis><atheroprotection><atheroprotective><atherosclerotic disease><atherosclerotic vascular disease><beta-Lipoprotein Cholesterol><beta-Lipoproteins><bile acid anabolism><bile acid biosynthetic process><bile acid formation><bile acid metabolism><bile acid synthesis><bile metabolism><biological signal transduction><bowel><burden of disease><burden of illness><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cholesterol absorption><design><designing><developmental><dietary lipid><diets><disease burden><early onset><ezetimib><ezetimibe><fat metabolism><gut-liver axis><hepatic body system><hepatic organ system><high blood cholesterol><hypercholesterolemia><improved><in vivo><intervention therapy><lipid metabolism><muricholic acid><novel><pathway><protection pathway><protective pathway><social role><tool><transcriptome sequencing><transcriptomic sequencing><uptake>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Thomas A Vallim

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$725,001

FY 2026

Project Title

Targeting the gut-liver axis in cardiovascular disease

Grant Number:

5R01HL163908-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Cardiovascular Disease (CVD) is the leading cause of death in the United States. Atherosclerosis is a hallmark of CVD and underlies many adverse events. Increased dietary lipid intake is a major contributor to the increased CVD disease burden. Elevated plasma lipids, particularly in the for...

Research Terms

<21+ years old><ASCVD><Acceleration><Acids><Adult><Adult Human><Adverse Experience><Adverse event><Affect><Assay><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Bacterial Toxins><Bile><Bile Acid Biosynthesis><Bile Acid Biosynthesis Pathway><Bile Acids><Bile Juice><Bile fluid><Bioassay><Biological Assay><Blood Plasma><CP7A><CRISPR><CRISPR/Cas system><CYP12><CYP2C><CYP2C19><CYP2C19 gene><CYP7A1><CYP7A1 gene><CYP8B1><CYP8B1 gene><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular Diseases><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chemical Structure><Chenic Acid><Chenique Acid><Chenodeoxycholic Acid><Chenodesoxycholic acid><Chenodiol><Cholalic Acids><Cholesterol><Cholesterol Esters><Cholesteryl Esters><Cholic Acids><Clustered Regularly Interspaced Short Palindromic Repeats><Communication><Cytochrome P450, Subfamily IIC, Polypeptide 19><Cytochrome P450, Subfamily VIIIB, Polypeptide 1><Detergents><Development><Diet><Dietary Fats><Dietary Fatty Acid><Disease><Disorder><Enzyme Gene><Enzymes><Fatty Acids><Gallodesoxycholic Acid><Gene Expression><Genes><Genetic study><Gut Epithelial Permeability><Gut Hyperpermeability><Gut permeability><Health system><Henohol><Hepatic><Human Genetics><Hypercholesteremia><Immune><Immunes><Inflammation><Inflammatory><Intake><Intermediary Metabolism><Intestinal><Intestinal Epithelial Permeability><Intestinal Hyperpermeability><Intestinal Leakage><Intestinal permeability><Intestines><Intracellular Communication and Signaling><LDL><LDL Cholesterol><LDL Cholesterol Lipoproteins><LDL Lipoproteins><Leaky Gut><Lipids><Liver><Low Density Lipoprotein Cholesterol><Low-Density Lipoproteins><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measures><Mediating><Mephenytoin 4-Prime Hydroxylase><Metabolic Processes><Metabolism><Mice><Mice Mammals><Murine><Mus><Nutrient><P450C2C><Pathogenesis><Pathway interactions><Plasma><Plasma Serum><Property><Public Health><RNA Seq><RNA sequencing><RNAseq><Reticuloendothelial System, Serum, Plasma><Role><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Sterol 12-alpha-Hydroxylase><System><Testing><Therapeutic><Therapeutic Intervention><Triacylglycerol><Triglycerides><United States><Zetia><absorption><adulthood><atheromatosis><atheroprotection><atheroprotective><atherosclerotic disease><atherosclerotic vascular disease><beta-Lipoprotein Cholesterol><beta-Lipoproteins><bile acid anabolism><bile acid biosynthetic process><bile acid formation><bile acid metabolism><bile acid synthesis><bile metabolism><biological signal transduction><bowel><burden of disease><burden of illness><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cholesterol absorption><design><designing><developmental><dietary lipid><diets><disease burden><early onset><ezetimib><ezetimibe><fat metabolism><gut-liver axis><hepatic body system><hepatic organ system><high blood cholesterol><hypercholesterolemia><improved><in vivo><intervention therapy><lipid metabolism><muricholic acid><novel><pathway><protection pathway><protective pathway><social role><tool><transcriptome sequencing><transcriptomic sequencing><uptake>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PARAG GOYAL

WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$706,946

FY 2026

Project Title

Preventing Myocardial Events of Aging: A PREVENTABLE Ancillary Study

Grant Number:

5R01AG085420-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY The aging vasculature and associated inflammation converge as a powerful force to cause two of the most common cardiovascular conditions in older adults aged at least 75 years—heart failure with preserved ejection fraction (HFpEF) and acute myocardial infarction (AMI). Despite the ne...

Research Terms

<21+ years old><Active Follow-up><Acute myocardial infarct><Acute myocardial infarction><Address><Adult><Adult Human><Affect><Aging><Amentia><Ancillary Study><Benefits and Risks><Biological><Biological Markers><Biometrics><Biometry><Biostatistics><Cardiac Abnormalities><Cardiac infarction><Cardiology><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Classification><Clinical><Clinical Trials><Code><Coding System><Computerized Medical Record><Data><Dementia><Detection><Diagnosis><Diagnostic><Diastolic heart failure><Disease><Disorder><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Elderly><Electronic Medical Record><Evaluation><Event><Funding><Goals><Guidelines><HF with preserved ejection fraction><HFpEF><Heart Abnormalities><Heart Vascular><Hospital Admission><Hospitalization><ICD-10><Inflammation><Infrastructure><International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10)><Ischemia><Knowledge><Lipids><Medical><Medical Records><Modernization><Morbidity><Myocardial><Myocardial Infarct><Myocardial Infarction><NHLBI><NIH><National Heart, Lung, and Blood Institute><National Institutes of Health><Natriuretic Peptide Hormones><Natriuretic Peptides><Observational Study><Outcome><Parents><Participant><Performance><Population><Preventative strategy><Prevention strategy><Preventive strategy><Public Health><Qualifying><Randomized, Controlled Trials><Reasons for Geographic And Racial Differences in Stroke><Records><Reporting><Research><Research Design><Retrieval><Risk><Risk Reduction><Site><Strategic vision><Study Type><Systematics><Testing><Troponin><United States National Institutes of Health><Vascular aging><Woman><active followup><adjudication><adjudicative process and procedure><adulthood><advanced age><aged><bio-markers><biologic><biologic marker><biomarker><cardiac infarct><cardiovascular disease epidemiology><cardiovascular disorder epidemiology><cardiovascular epidemiology><circulatory system><clinical practice><coronary attack><coronary infarct><coronary infarction><cost><detection sensitivity><disease prevention><disorder prevention><endothelial dysfunction><evidence base><experience><follow up><follow-up><followed up><followup><geriatric><health goals><heart attack><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart infarct><heart infarction><improved><insight><medical claims><men><mortality><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><observational research study><observational survey><older adult><older adulthood><parent><preserved ejection fraction heart failure><prevent><preventing><primary outcome><randomized control trial><randomized placebo control trial><randomized placebo controlled trial><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><secondary outcome><senior citizen><study design><treatment pattern><vasculature aging>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Hong Chen

UNIVERSITY OF CALIFORNIA RIVERSIDE, RIVERSIDE, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$697,761

FY 2026

Project Title

Role of PXR in drug-elicited cardiovascular disease

Grant Number:

5R01HL167206-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Antipsychotic therapy is widely used in the treatment of psychiatric conditions including bipolar disorder, schizophrenia, and major depressive disorder. These conditions, which together affect more than 20% of the population, usually require lifelong medication. Atypical antipsychot...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Changcheng Zhou

UNIVERSITY OF CALIFORNIA RIVERSIDE, RIVERSIDE, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$697,761

FY 2026

Project Title

Role of PXR in drug-elicited cardiovascular disease

Grant Number:

5R01HL167206-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Antipsychotic therapy is widely used in the treatment of psychiatric conditions including bipolar disorder, schizophrenia, and major depressive disorder. These conditions, which together affect more than 20% of the population, usually require lifelong medication. Atypical antipsychot...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Minsoo Kim

UNIVERSITY OF ROCHESTER, ROCHESTER, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$683,310

FY 2026

Project Title

T cell migration and cardiovascular toxicity in immunotherapy

Grant Number:

5R01AI147362-07

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/22/2019

End Date:

1/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

T cell migration and cardiovascular toxicity in immunotherapy. Adoptive T-cell transfer therapy has emerged as a promising therapeutic option with complete and durable responses in several disease conditions such as viral infection, autoimmune disease, atherosclerosis, and cancer. However, severe im...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Richard E Waugh

UNIVERSITY OF ROCHESTER, ROCHESTER, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$683,310

FY 2026

Project Title

T cell migration and cardiovascular toxicity in immunotherapy

Grant Number:

5R01AI147362-07

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/22/2019

End Date:

1/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

T cell migration and cardiovascular toxicity in immunotherapy. Adoptive T-cell transfer therapy has emerged as a promising therapeutic option with complete and durable responses in several disease conditions such as viral infection, autoimmune disease, atherosclerosis, and cancer. However, severe im...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Petter Bjornstad

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$654,539

FY 2026

Project Title

Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients

Grant Number:

5R01DK137844-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/16/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT ABSTRACT Kidney transplantation is the desired treatment for kidney failure. While short term kidney transplantation outcomes have improved significantly, long-term outcomes remain suboptimal. Death with functioning graft from cardiovascular disease (CVD) is a major cause of graft loss. The ...

Research Terms

<21+ years old><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Adherence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Albumins><Albuminuria><Allografting><Aorta><Attenuated><Biology><Biopsy><Blood Vessels><Body Tissues><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cause of Death><Cell Communication and Signaling><Cell Signaling><Cessation of life><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Trials><Complex><Continuous Glucose Monitor><Creatinine><Data><Death><Diabetes Mellitus><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drugs><Event><Exclusion><FK506 Binding Protein 12-Rapamycin Associated Protein 1><FKBP12 Rapamycin Complex Associated Protein 1><FRAP1><FRAP1 gene><FRAP2><Feedback><Fibrosis><GU Infection><General Population><General Public><Genitourinary System Infection><Genitourinary infection><Glomerular Filtration Rate><Graft Rejection><Heart Vascular><Hypoglycemic Agents><Hypoglycemic Drugs><Hypoglycemics><Hypoxia><Hypoxic><Immune response><Intermediary Metabolism><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Grafting><Kidney Insufficiency><Kidney Transplantation><Kidney Transplants><Kidney Tubules><Kidney Urinary System><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Mechanistic Target of Rapamycin><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Metabolic><Metabolic Processes><Metabolism><Methods><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><NIDDM><NMR Imaging><NMR Tomography><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Magnetic Resonance Imaging><Outcome><Oxygen Deficiency><Participant><Patients><Perfusion><Peripheral><Pharmaceutical Preparations><Phenotype><Physiologic pulse><Placebo Control><Placebos><Play><Population><Pulse><RAFT1><Randomized><Randomized, Controlled Trials><Renal Disease><Renal Failure><Renal Grafting><Renal Insufficiency><Renal Transplantation><Renal Transplants><Renal function><Renal tubule structure><Risk><SGLT 2 inhibitor><SGLT2i><Safety><Sham Treatment><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Sodium glucose co-transporter 2 inhibitor><Specific qualifier value><Specified><Stable Diabetes Mellitus><Structure><T2 DM><T2D><T2DM><Testing><Tissues><Transplant Recipients><Transplant Rejection><Transplantation Rejection><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Urinary tract infection><Urinary tract infectious disease><Urine><Zeugmatography><acute kidney injury><adult onset diabetes><adulthood><antihyperglycemic><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><attenuate><attenuates><attenuation><biological signal transduction><cardiac MRI><cardiac function><cardiac magnetic resonance imaging><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular function><cardiovascular graft><cardiovascular health><cardiovascular transplantation><chronic kidney disease><circulatory system><clinical phenotype><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><diabetes><diabetic><disease risk><disorder risk><drug/agent><experience><function of the heart><graft failure><graft function><heart function><host response><immune system response><immunoresponse><improved><infectious disease of genitourinary system><innovate><innovation><innovative><insight><interest><interstitial><ketosis resistant diabetes><kidney allograft><kidney biopsy><kidney disorder><kidney fibrosis><kidney function><kidney tx><loss of function><mTOR><mammalian target of rapamycin><maturity onset diabetes><molecular profile><molecular signature><morphometry><mortality><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><placebo controlled><post-transplant><post-transplantation><posttransplant><posttransplantation><preservation><pressure><primary outcome><protective effect><randomisation><randomization><randomized control trial><randomly assigned><renal><renal allograft><renal biopsy><renal disorder><renal fibrosis><renal tubule><restoration><scRNA sequencing><scRNA-seq><sham therapy><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><standard of care><transplant patient><type 2 DM><type II DM><type two diabetes><urinary infection><urogenital infection><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jessica B Kendrick

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$654,539

FY 2026

Project Title

Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients

Grant Number:

5R01DK137844-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/16/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT ABSTRACT Kidney transplantation is the desired treatment for kidney failure. While short term kidney transplantation outcomes have improved significantly, long-term outcomes remain suboptimal. Death with functioning graft from cardiovascular disease (CVD) is a major cause of graft loss. The ...

Research Terms

<21+ years old><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Adherence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Albumins><Albuminuria><Allografting><Aorta><Attenuated><Biology><Biopsy><Blood Vessels><Body Tissues><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cause of Death><Cell Communication and Signaling><Cell Signaling><Cessation of life><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Trials><Complex><Continuous Glucose Monitor><Creatinine><Data><Death><Diabetes Mellitus><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drugs><Event><Exclusion><FK506 Binding Protein 12-Rapamycin Associated Protein 1><FKBP12 Rapamycin Complex Associated Protein 1><FRAP1><FRAP1 gene><FRAP2><Feedback><Fibrosis><GU Infection><General Population><General Public><Genitourinary System Infection><Genitourinary infection><Glomerular Filtration Rate><Graft Rejection><Heart Vascular><Hypoglycemic Agents><Hypoglycemic Drugs><Hypoglycemics><Hypoxia><Hypoxic><Immune response><Intermediary Metabolism><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Grafting><Kidney Insufficiency><Kidney Transplantation><Kidney Transplants><Kidney Tubules><Kidney Urinary System><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Mechanistic Target of Rapamycin><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Metabolic><Metabolic Processes><Metabolism><Methods><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><NIDDM><NMR Imaging><NMR Tomography><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Magnetic Resonance Imaging><Outcome><Oxygen Deficiency><Participant><Patients><Perfusion><Peripheral><Pharmaceutical Preparations><Phenotype><Physiologic pulse><Placebo Control><Placebos><Play><Population><Pulse><RAFT1><Randomized><Randomized, Controlled Trials><Renal Disease><Renal Failure><Renal Grafting><Renal Insufficiency><Renal Transplantation><Renal Transplants><Renal function><Renal tubule structure><Risk><SGLT 2 inhibitor><SGLT2i><Safety><Sham Treatment><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Sodium glucose co-transporter 2 inhibitor><Specific qualifier value><Specified><Stable Diabetes Mellitus><Structure><T2 DM><T2D><T2DM><Testing><Tissues><Transplant Recipients><Transplant Rejection><Transplantation Rejection><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Urinary tract infection><Urinary tract infectious disease><Urine><Zeugmatography><acute kidney injury><adult onset diabetes><adulthood><antihyperglycemic><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><attenuate><attenuates><attenuation><biological signal transduction><cardiac MRI><cardiac function><cardiac magnetic resonance imaging><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular function><cardiovascular graft><cardiovascular health><cardiovascular transplantation><chronic kidney disease><circulatory system><clinical phenotype><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><diabetes><diabetic><disease risk><disorder risk><drug/agent><experience><function of the heart><graft failure><graft function><heart function><host response><immune system response><immunoresponse><improved><infectious disease of genitourinary system><innovate><innovation><innovative><insight><interest><interstitial><ketosis resistant diabetes><kidney allograft><kidney biopsy><kidney disorder><kidney fibrosis><kidney function><kidney tx><loss of function><mTOR><mammalian target of rapamycin><maturity onset diabetes><molecular profile><molecular signature><morphometry><mortality><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><placebo controlled><post-transplant><post-transplantation><posttransplant><posttransplantation><preservation><pressure><primary outcome><protective effect><randomisation><randomization><randomized control trial><randomly assigned><renal><renal allograft><renal biopsy><renal disorder><renal fibrosis><renal tubule><restoration><scRNA sequencing><scRNA-seq><sham therapy><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><standard of care><transplant patient><type 2 DM><type II DM><type two diabetes><urinary infection><urogenital infection><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PETROS KOUTRAKIS

HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH, BOSTON, MA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$644,817

FY 2026

Project Title

A nationwide population-based study investigating the cardiovascular effects of exposure to particulate matter α-, β-, and γ-activities and individual radionuclides

Grant Number:

5R01ES035390-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in the U.S., and numerous studies have linked CVD to short- and long-term exposures to particulate air pollution (PM), however, the PM properties responsible for its toxicity are still not fully understood. Recently, we repor...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Antonella Zanobetti

HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH, BOSTON, MA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$644,817

FY 2026

Project Title

A nationwide population-based study investigating the cardiovascular effects of exposure to particulate matter α-, β-, and γ-activities and individual radionuclides

Grant Number:

5R01ES035390-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in the U.S., and numerous studies have linked CVD to short- and long-term exposures to particulate air pollution (PM), however, the PM properties responsible for its toxicity are still not fully understood. Recently, we repor...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jessica M Oakes

NORTHEASTERN UNIVERSITY, BOSTON, MA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$631,376

FY 2026

Project Title

Cardiopulmonary Risk Assessment from Smoke Exposure at the Wildland Urban Interface

Grant Number:

5R01ES033792-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/7/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Acute and chronic wildland fire smoke inhalation have been linked to increased mortality as well as respiratory and cardiovascular morbidity, though the extent to which the frequency and duration of exposure or the chemical and particle profiles of the smoke contribute to the observe...

Research Terms

<21+ years old><APOE><ASCVD><Acute><Adult><Adult Human><Advocate><Aerosols><Animals><Aorta><Apo-E><ApoE protein><Apolipoprotein E><Area><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Automobile Driving><Awareness><Behavior><Biological><Biology><Blood Circulation><Blood Pressure><Blood Serum><Bloodstream><Body Tissues><Breathing Mechanics><California><Cardiac><Cardiopulmonary><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Care Manager><Case Manager><Cell Body><Cells><Characteristics><Chemicals><Chemistry><Chemotactic Cytokines><Chronic><Circulation><Communities><Complex><Complex Mixtures><Computer Models><Computerized Models><Cor pulmonale><Coupling><Dangerousness><Deposit><Deposition><Development><Disease><Disorder><Dose><Douglas Fir><Dysfunction><EFRAC><Ejection Fraction><Elasticity><Engineering><Epidemiological data><Epidemiology data><Exposure to><Fire - disasters><Fires><Fostering><Frequencies><Functional disorder><Gases><Generations><Goals><Grant><Groups at risk><Health><Health Care><Heart><Heart Vascular><Homologous Chemotactic Cytokines><Household><Housing><Human><Hypercholesteremia><Individual><Infiltration><Inflammation><Inflammatory><Inhalation><Inhalation Toxicology><Inhaling><Intercrines><Interdisciplinary Research><Interdisciplinary Study><Investigators><Knowledge><Life><Link><Lung><Lung Respiratory System><Measures><Mice><Mice Mammals><Modeling><Modern Man><Morbidity><Multidisciplinary Collaboration><Multidisciplinary Research><Murine><Mus><Obstructive Lung Diseases><Organ><Outcome><PM0.1><PM2.5><PMMA><Particle Size><Particulate><Particulate Matter><People at risk><Persons><Persons at risk><Physiopathology><Policies><Policy Maker><Poly(methyl methacrylate)><Polymethyl Methacrylate><Polymethylmetacrylate><Polymethylmethacrylate><Population><Populations at Risk><Predisposition><Pseudotsuga menziesii><Public Health><Pulmonary Heart Disease><Pulmonary Heart Disorder><Recurrence><Recurrent><Research><Research Personnel><Researchers><Respiratory Disease><Respiratory Mechanics><Respiratory System Disease><Respiratory System Disorder><Risk Assessment><Rodent><Rodentia><Rodents Mammals><Role><SIS cytokines><Serum><Severities><Smoke><Source><Susceptibility><System><Testing><Tissues><Toxin><Trace metal><Ultrafine Particulates><Wildfire><Wood><Wood material><adulthood><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><biologic><biomass smoke><biomechanical analyses><biomechanical analysis><biomechanical assessment><biomechanical characterization><biomechanical evaluation><biomechanical measurement><biomechanical profiling><biomechanical test><cardiopulmonary disease><cardiopulmonary disorder><cardiovascular disorder><cardiovascular function><career><career development><chemoattractant cytokine><chemokine><circulatory system><computational modeling><computational models><computer based models><computerized modeling><conference><convention><cost><cytokine><density><developmental><driving><epidemiologic data><fine particles><fine particulate matter><fire><health assessment><high blood cholesterol><hypercholesterolemia><imaging in vivo><in vivo imaging><mortality><mouse model><murine model><novel><obstructive pulmonary diseases><particle><pathophysiology><pollutant><polyurethane foam><pressure><programs><pulmonary><respiratory><response><risk stratification><smoke inhalation><social role><stratify risk><summit><symposia><symposium><ultrafine particle><ultrafine particulate matter><wild fire><wildland fire>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

STEVEN A FARBER

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$607,278

FY 2026

Project Title

Defining the role of PLA2G12B on apoB-containing lipoprotein assembly, plasma levels, metabolism and cardiovascular disease risk

Grant Number:

5R01DK138195-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY- Triglyceride (TG)-rich ApoB-containing lipoproteins (BLP) are micelle-like particles that enable efficient transport of lipids through the bloodstream, but also promote atherosclerotic cardiovascular disease (CVD), the leading cause of death worldwide. Although the lipid content of ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

M Mahmood Hussain

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$607,278

FY 2026

Project Title

Defining the role of PLA2G12B on apoB-containing lipoprotein assembly, plasma levels, metabolism and cardiovascular disease risk

Grant Number:

5R01DK138195-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY- Triglyceride (TG)-rich ApoB-containing lipoproteins (BLP) are micelle-like particles that enable efficient transport of lipids through the bloodstream, but also promote atherosclerotic cardiovascular disease (CVD), the leading cause of death worldwide. Although the lipid content of ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Markus Hilpert

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$603,938

FY 2026

Project Title

Air Pollution and Cardiovascular Disease in American Indian Communities

Grant Number:

5R01ES035617-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Increasing evidence indicates that air pollution is a relevant risk factor for cardiovascular disease (CVD) even at low exposure levels. American Indian populations experience the highest burden of CVD compared to other racial/ethnic groups in the US and thus may be particularly vulnerable ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marianthi-Anna Kioumourtzoglou

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$603,938

FY 2026

Project Title

Air Pollution and Cardiovascular Disease in American Indian Communities

Grant Number:

5R01ES035617-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Increasing evidence indicates that air pollution is a relevant risk factor for cardiovascular disease (CVD) even at low exposure levels. American Indian populations experience the highest burden of CVD compared to other racial/ethnic groups in the US and thus may be particularly vulnerable ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ana Navas-Acien

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$603,938

FY 2026

Project Title

Air Pollution and Cardiovascular Disease in American Indian Communities

Grant Number:

5R01ES035617-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Increasing evidence indicates that air pollution is a relevant risk factor for cardiovascular disease (CVD) even at low exposure levels. American Indian populations experience the highest burden of CVD compared to other racial/ethnic groups in the US and thus may be particularly vulnerable ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

AKIRA SEKIKAWA

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 58/100

Training-friendly

Solid budget

Very recent

Active award

$430,646

FY 2026

Project Title

Cardiovascular Epidemiology Training Program

Grant Number:

5T32HL083825-18

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

5/1/2008

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract This proposal is the competing continuation of the University of Pittsburgh T32 Training Program in Cardiovascular Epidemiology funded by NHLBI since 2008. Cardiovascular disease (CVD) remains the leading cause of death despite a >50% decline in age-adjusted CVD mortality in...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CHUNMING DONG

UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, CORAL GABLES, FL

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$383,750

FY 2026

Project Title

The role of extracellular vesicle-associated MicroRNAs in HIV-associated atherosclerosis

Grant Number:

5R01HL162579-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

People living with HIV (PLWH) have a significantly higher risk of cardiovascular diseases (CVD) compared to their HIV negative counterparts. However, the underlying mechanisms that drive this increased CVD risk remain elusive. Extracellular vesicles (EVs)/exosomes are released by all cells and widel...

Research Terms

<3' Untranslated Regions><3'UTR><AIDS><AIDS Virus><APOE><ASCVD><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Advanced HIV><Adverse effects><Affect><Anti-HIV Positivity><Apo-E><ApoE protein><Apolipoprotein E><Apoptosis><Apoptosis Pathway><Arterial Fatty Streak><Arteries><Atherogenicity><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerotic Cardiovascular Disease><BABL><BABL Gene><Biological><Blood Plasma><Body Fluids><Bone Marrow><Bone Marrow Blood-Deriving Cell><Bone Marrow Blood-Forming Cell><Bone Marrow Cells><Bone Marrow Reticuloendothelial System><CD4 Lymphocyte Count><CD4+ Cell Counts><CD4+ Counts><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Pathology><Cardiovascular system><Cell Body><Cell Communication><Cell Interaction><Cell Isolation><Cell Segregation><Cell Senescence Induction><Cell Separation><Cell Separation Technology><Cell-to-Cell Interaction><Cells><Chronic><Data><Development><Distant><Endothelial Cells><Endothelium><Engineering><Equilibrium><Exposure to><Foundations><Genes><Genetic><Goals><Grant><HIV><HIV Infections><HIV Positive><HIV Positivity><HIV Seroconversion><HIV Seronegativities><HIV Seronegativity><HIV Seropositivity><HIV antibody positive><HIV individuals><HIV infected individuals><HIV infected persons><HIV negative><HIV people><HIV positive individuals><HIV positive people><HIV viral infection><HIV virus infection><HIV+><HIV-1 infection><HMGA2><HMGA2 gene><HMGIC><HMGIC Gene><HTLV-III Seroconversion><HTLV-III Seronegativities><HTLV-III Seronegativity><HTLV-III Seropositivity><Heart Vascular><High Mobility Group AT-Hook 2 Gene><High Mobility Group Protein HMGIC Breakpoint Associated with Benign Lipoma Gene><High Mobility Group Protein Isoform I-C Gene><High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C Gene><High-Mobility Group Protein HMGI-C Gene><Human><Human Immunodeficiency Viruses><Immune Cell Activation><Impairment><In Vitro><Infection><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Inflammation><Inflammatory><Injury><LAV-HTLV-III><LIPO Gene><Leiomyocyte><Lipids><Liquid substance><Lymphadenopathy-Associated Virus><Mediating><Mediator><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Messenger RNA><Mice><Mice Mammals><MicroRNAs><Modern Man><Modification><Molecular><Morbidity><Murine><Mus><PLWH><PWH><Pathway interactions><Plasma><Plasma Serum><Preventative strategy><Prevention strategy><Preventive strategy><Process><Programmed Cell Death><Proliferating><Proteins><Publishing><QOL><Quality of life><RNA Seq><RNA sequencing><RNAseq><Regulation><Resistance><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Severe HIV Disease><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Solid><T4 Lymphocyte Count><Testing><Urine><Vascular Endothelial Cell><Vesicle><Viral><Viral Burden><Viral Load><Viral Load result><Virus-HIV><Writing><accelerated aging><accelerated biological age><accelerated biological aging><age acceleration><antagonism><antagonist><antiretroviral therapy><antiretroviral treatment><atherogenesis><atheromatosis><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic vascular disease><balance><balance function><biologic><candidate validation><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cell sorting><cell type><cellular aging induction><cellular senescence induction><circulatory system><clinical care><developmental><endothelial progenitor><endothelial progenitor cell><endothelial stem cell><exosome><extracellular vesicles><fluid><global gene expression><global transcription profile><high risk><human immunodeficiency virus infection><immune activation><improved><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><injuries><injury and repair><injury to the vasculature><isolated individuals><isolated people><latent HIV reservoir><latent HIV-1 reservoir><latent HIV1 reservoir><liquid><lonely individuals><lonely people><mRNA><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><miRNA><migration><mortality><nano sized><nanosized><novel><overexpress><overexpression><pathway><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><peripheral blood><plaques in atherosclerosis><premature><prematurity><reconstitute><reconstitution><resistant><senescence><senescence induction><senescent><social role><transcriptome><transcriptome sequencing><transcriptomic sequencing><treatment strategy><vascular injury><virtual>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Derek Michael Dykxhoorn

UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, CORAL GABLES, FL

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$383,750

FY 2026

Project Title

The role of extracellular vesicle-associated MicroRNAs in HIV-associated atherosclerosis

Grant Number:

5R01HL162579-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

People living with HIV (PLWH) have a significantly higher risk of cardiovascular diseases (CVD) compared to their HIV negative counterparts. However, the underlying mechanisms that drive this increased CVD risk remain elusive. Extracellular vesicles (EVs)/exosomes are released by all cells and widel...

Research Terms

<3' Untranslated Regions><3'UTR><AIDS><AIDS Virus><APOE><ASCVD><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Advanced HIV><Adverse effects><Affect><Anti-HIV Positivity><Apo-E><ApoE protein><Apolipoprotein E><Apoptosis><Apoptosis Pathway><Arterial Fatty Streak><Arteries><Atherogenicity><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerotic Cardiovascular Disease><BABL><BABL Gene><Biological><Blood Plasma><Body Fluids><Bone Marrow><Bone Marrow Blood-Deriving Cell><Bone Marrow Blood-Forming Cell><Bone Marrow Cells><Bone Marrow Reticuloendothelial System><CD4 Lymphocyte Count><CD4+ Cell Counts><CD4+ Counts><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Pathology><Cardiovascular system><Cell Body><Cell Communication><Cell Interaction><Cell Isolation><Cell Segregation><Cell Senescence Induction><Cell Separation><Cell Separation Technology><Cell-to-Cell Interaction><Cells><Chronic><Data><Development><Distant><Endothelial Cells><Endothelium><Engineering><Equilibrium><Exposure to><Foundations><Genes><Genetic><Goals><Grant><HIV><HIV Infections><HIV Positive><HIV Positivity><HIV Seroconversion><HIV Seronegativities><HIV Seronegativity><HIV Seropositivity><HIV antibody positive><HIV individuals><HIV infected individuals><HIV infected persons><HIV negative><HIV people><HIV positive individuals><HIV positive people><HIV viral infection><HIV virus infection><HIV+><HIV-1 infection><HMGA2><HMGA2 gene><HMGIC><HMGIC Gene><HTLV-III Seroconversion><HTLV-III Seronegativities><HTLV-III Seronegativity><HTLV-III Seropositivity><Heart Vascular><High Mobility Group AT-Hook 2 Gene><High Mobility Group Protein HMGIC Breakpoint Associated with Benign Lipoma Gene><High Mobility Group Protein Isoform I-C Gene><High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C Gene><High-Mobility Group Protein HMGI-C Gene><Human><Human Immunodeficiency Viruses><Immune Cell Activation><Impairment><In Vitro><Infection><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Inflammation><Inflammatory><Injury><LAV-HTLV-III><LIPO Gene><Leiomyocyte><Lipids><Liquid substance><Lymphadenopathy-Associated Virus><Mediating><Mediator><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Messenger RNA><Mice><Mice Mammals><MicroRNAs><Modern Man><Modification><Molecular><Morbidity><Murine><Mus><PLWH><PWH><Pathway interactions><Plasma><Plasma Serum><Preventative strategy><Prevention strategy><Preventive strategy><Process><Programmed Cell Death><Proliferating><Proteins><Publishing><QOL><Quality of life><RNA Seq><RNA sequencing><RNAseq><Regulation><Resistance><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Severe HIV Disease><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Solid><T4 Lymphocyte Count><Testing><Urine><Vascular Endothelial Cell><Vesicle><Viral><Viral Burden><Viral Load><Viral Load result><Virus-HIV><Writing><accelerated aging><accelerated biological age><accelerated biological aging><age acceleration><antagonism><antagonist><antiretroviral therapy><antiretroviral treatment><atherogenesis><atheromatosis><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic vascular disease><balance><balance function><biologic><candidate validation><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cell sorting><cell type><cellular aging induction><cellular senescence induction><circulatory system><clinical care><developmental><endothelial progenitor><endothelial progenitor cell><endothelial stem cell><exosome><extracellular vesicles><fluid><global gene expression><global transcription profile><high risk><human immunodeficiency virus infection><immune activation><improved><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><injuries><injury and repair><injury to the vasculature><isolated individuals><isolated people><latent HIV reservoir><latent HIV-1 reservoir><latent HIV1 reservoir><liquid><lonely individuals><lonely people><mRNA><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><miRNA><migration><mortality><nano sized><nanosized><novel><overexpress><overexpression><pathway><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><peripheral blood><plaques in atherosclerosis><premature><prematurity><reconstitute><reconstitution><resistant><senescence><senescence induction><senescent><social role><transcriptome><transcriptome sequencing><transcriptomic sequencing><treatment strategy><vascular injury><virtual>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DUSHYANTHA JAYAWEERA

UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, CORAL GABLES, FL

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$383,750

FY 2026

Project Title

The role of extracellular vesicle-associated MicroRNAs in HIV-associated atherosclerosis

Grant Number:

5R01HL162579-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

People living with HIV (PLWH) have a significantly higher risk of cardiovascular diseases (CVD) compared to their HIV negative counterparts. However, the underlying mechanisms that drive this increased CVD risk remain elusive. Extracellular vesicles (EVs)/exosomes are released by all cells and widel...

Research Terms

<3' Untranslated Regions><3'UTR><AIDS><AIDS Virus><APOE><ASCVD><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Advanced HIV><Adverse effects><Affect><Anti-HIV Positivity><Apo-E><ApoE protein><Apolipoprotein E><Apoptosis><Apoptosis Pathway><Arterial Fatty Streak><Arteries><Atherogenicity><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerotic Cardiovascular Disease><BABL><BABL Gene><Biological><Blood Plasma><Body Fluids><Bone Marrow><Bone Marrow Blood-Deriving Cell><Bone Marrow Blood-Forming Cell><Bone Marrow Cells><Bone Marrow Reticuloendothelial System><CD4 Lymphocyte Count><CD4+ Cell Counts><CD4+ Counts><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Pathology><Cardiovascular system><Cell Body><Cell Communication><Cell Interaction><Cell Isolation><Cell Segregation><Cell Senescence Induction><Cell Separation><Cell Separation Technology><Cell-to-Cell Interaction><Cells><Chronic><Data><Development><Distant><Endothelial Cells><Endothelium><Engineering><Equilibrium><Exposure to><Foundations><Genes><Genetic><Goals><Grant><HIV><HIV Infections><HIV Positive><HIV Positivity><HIV Seroconversion><HIV Seronegativities><HIV Seronegativity><HIV Seropositivity><HIV antibody positive><HIV individuals><HIV infected individuals><HIV infected persons><HIV negative><HIV people><HIV positive individuals><HIV positive people><HIV viral infection><HIV virus infection><HIV+><HIV-1 infection><HMGA2><HMGA2 gene><HMGIC><HMGIC Gene><HTLV-III Seroconversion><HTLV-III Seronegativities><HTLV-III Seronegativity><HTLV-III Seropositivity><Heart Vascular><High Mobility Group AT-Hook 2 Gene><High Mobility Group Protein HMGIC Breakpoint Associated with Benign Lipoma Gene><High Mobility Group Protein Isoform I-C Gene><High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C Gene><High-Mobility Group Protein HMGI-C Gene><Human><Human Immunodeficiency Viruses><Immune Cell Activation><Impairment><In Vitro><Infection><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Inflammation><Inflammatory><Injury><LAV-HTLV-III><LIPO Gene><Leiomyocyte><Lipids><Liquid substance><Lymphadenopathy-Associated Virus><Mediating><Mediator><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Messenger RNA><Mice><Mice Mammals><MicroRNAs><Modern Man><Modification><Molecular><Morbidity><Murine><Mus><PLWH><PWH><Pathway interactions><Plasma><Plasma Serum><Preventative strategy><Prevention strategy><Preventive strategy><Process><Programmed Cell Death><Proliferating><Proteins><Publishing><QOL><Quality of life><RNA Seq><RNA sequencing><RNAseq><Regulation><Resistance><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Severe HIV Disease><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Solid><T4 Lymphocyte Count><Testing><Urine><Vascular Endothelial Cell><Vesicle><Viral><Viral Burden><Viral Load><Viral Load result><Virus-HIV><Writing><accelerated aging><accelerated biological age><accelerated biological aging><age acceleration><antagonism><antagonist><antiretroviral therapy><antiretroviral treatment><atherogenesis><atheromatosis><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic vascular disease><balance><balance function><biologic><candidate validation><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cell sorting><cell type><cellular aging induction><cellular senescence induction><circulatory system><clinical care><developmental><endothelial progenitor><endothelial progenitor cell><endothelial stem cell><exosome><extracellular vesicles><fluid><global gene expression><global transcription profile><high risk><human immunodeficiency virus infection><immune activation><improved><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><injuries><injury and repair><injury to the vasculature><isolated individuals><isolated people><latent HIV reservoir><latent HIV-1 reservoir><latent HIV1 reservoir><liquid><lonely individuals><lonely people><mRNA><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><miRNA><migration><mortality><nano sized><nanosized><novel><overexpress><overexpression><pathway><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><peripheral blood><plaques in atherosclerosis><premature><prematurity><reconstitute><reconstitution><resistant><senescence><senescence induction><senescent><social role><transcriptome><transcriptome sequencing><transcriptomic sequencing><treatment strategy><vascular injury><virtual>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Liyong Wang

UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, CORAL GABLES, FL

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$383,750

FY 2026

Project Title

The role of extracellular vesicle-associated MicroRNAs in HIV-associated atherosclerosis

Grant Number:

5R01HL162579-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

People living with HIV (PLWH) have a significantly higher risk of cardiovascular diseases (CVD) compared to their HIV negative counterparts. However, the underlying mechanisms that drive this increased CVD risk remain elusive. Extracellular vesicles (EVs)/exosomes are released by all cells and widel...

Research Terms

<3' Untranslated Regions><3'UTR><AIDS><AIDS Virus><APOE><ASCVD><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Advanced HIV><Adverse effects><Affect><Anti-HIV Positivity><Apo-E><ApoE protein><Apolipoprotein E><Apoptosis><Apoptosis Pathway><Arterial Fatty Streak><Arteries><Atherogenicity><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerotic Cardiovascular Disease><BABL><BABL Gene><Biological><Blood Plasma><Body Fluids><Bone Marrow><Bone Marrow Blood-Deriving Cell><Bone Marrow Blood-Forming Cell><Bone Marrow Cells><Bone Marrow Reticuloendothelial System><CD4 Lymphocyte Count><CD4+ Cell Counts><CD4+ Counts><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Pathology><Cardiovascular system><Cell Body><Cell Communication><Cell Interaction><Cell Isolation><Cell Segregation><Cell Senescence Induction><Cell Separation><Cell Separation Technology><Cell-to-Cell Interaction><Cells><Chronic><Data><Development><Distant><Endothelial Cells><Endothelium><Engineering><Equilibrium><Exposure to><Foundations><Genes><Genetic><Goals><Grant><HIV><HIV Infections><HIV Positive><HIV Positivity><HIV Seroconversion><HIV Seronegativities><HIV Seronegativity><HIV Seropositivity><HIV antibody positive><HIV individuals><HIV infected individuals><HIV infected persons><HIV negative><HIV people><HIV positive individuals><HIV positive people><HIV viral infection><HIV virus infection><HIV+><HIV-1 infection><HMGA2><HMGA2 gene><HMGIC><HMGIC Gene><HTLV-III Seroconversion><HTLV-III Seronegativities><HTLV-III Seronegativity><HTLV-III Seropositivity><Heart Vascular><High Mobility Group AT-Hook 2 Gene><High Mobility Group Protein HMGIC Breakpoint Associated with Benign Lipoma Gene><High Mobility Group Protein Isoform I-C Gene><High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C Gene><High-Mobility Group Protein HMGI-C Gene><Human><Human Immunodeficiency Viruses><Immune Cell Activation><Impairment><In Vitro><Infection><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Inflammation><Inflammatory><Injury><LAV-HTLV-III><LIPO Gene><Leiomyocyte><Lipids><Liquid substance><Lymphadenopathy-Associated Virus><Mediating><Mediator><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Messenger RNA><Mice><Mice Mammals><MicroRNAs><Modern Man><Modification><Molecular><Morbidity><Murine><Mus><PLWH><PWH><Pathway interactions><Plasma><Plasma Serum><Preventative strategy><Prevention strategy><Preventive strategy><Process><Programmed Cell Death><Proliferating><Proteins><Publishing><QOL><Quality of life><RNA Seq><RNA sequencing><RNAseq><Regulation><Resistance><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Severe HIV Disease><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Solid><T4 Lymphocyte Count><Testing><Urine><Vascular Endothelial Cell><Vesicle><Viral><Viral Burden><Viral Load><Viral Load result><Virus-HIV><Writing><accelerated aging><accelerated biological age><accelerated biological aging><age acceleration><antagonism><antagonist><antiretroviral therapy><antiretroviral treatment><atherogenesis><atheromatosis><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic vascular disease><balance><balance function><biologic><candidate validation><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cell sorting><cell type><cellular aging induction><cellular senescence induction><circulatory system><clinical care><developmental><endothelial progenitor><endothelial progenitor cell><endothelial stem cell><exosome><extracellular vesicles><fluid><global gene expression><global transcription profile><high risk><human immunodeficiency virus infection><immune activation><improved><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><injuries><injury and repair><injury to the vasculature><isolated individuals><isolated people><latent HIV reservoir><latent HIV-1 reservoir><latent HIV1 reservoir><liquid><lonely individuals><lonely people><mRNA><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><miRNA><migration><mortality><nano sized><nanosized><novel><overexpress><overexpression><pathway><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><peripheral blood><plaques in atherosclerosis><premature><prematurity><reconstitute><reconstitution><resistant><senescence><senescence induction><senescent><social role><transcriptome><transcriptome sequencing><transcriptomic sequencing><treatment strategy><vascular injury><virtual>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

NEIL MEHTA

UNIVERSITY OF TEXAS MED BR GALVESTON, GALVESTON, TX

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$370,570

FY 2026

Project Title

Identifying the Causes of the Stagnation in National U.S. Cardiovascular Disease Mortality

Grant Number:

5R01AG075208-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2023

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Since 2010, U.S. life expectancy improvements have stalled and in certain years declined. Much attention to this stall has focused on the role of rising drug overdose deaths. In published work, however, our team has identified stagnating declines in cardiovascular disease (CVD) mort...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Robert Scott Ross

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 58/100

Training-friendly

Solid budget

Very recent

Active award

$342,360

FY 2026

Project Title

UCSD Future Faculty of Cardiovascular Sciences (FOCUS)

Grant Number:

5R25HL145817-08

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/8/2019

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract A diverse U.S. biomedical research workforce is essential for developing innovation in basic, translational and clinical research and healthcare and is necessary for improving the nation’s health. The NIH has identified key issues contributing to the disproportionate representation of under...

Research Terms

<0-11 years old><Academic skills><Adult-Onset Diabetes Mellitus><African American group><African American individual><African American people><African American population><African Americans><American><American Heart Association><Applications Grants><Area><Award><Basic Research><Basic Science><Biomedical Research><California><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Career Mobility><Caring><Categories><Censuses><Child><Child Youth><Children (0-21)><Client satisfaction><Clinical Research><Clinical Study><Communication><Data><Decrease health disparities><Department of Health and Human Services><Development><Development and Research><Diagnosis><Disparities><Disparity><EXTMR><Education><Educational aspects><Ethnic Origin><Ethnicity><Extramural><Extramural Activities><Faculty><Fellowship Program><Fostering><Frequencies><Funding><Future Teacher><Goals><Grant><Grant Proposals><Health><Health Care><Health disparity mitigation><Health disparity reduction><Heart Vascular><High Prevalence><Hispanic Americans><History><Home><Hypertension><Individual><Individuals from minority><Individuals of minority><Institution><Insurance><Investigators><K-Awards><K-Series Research Career Programs><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leadership><Lower health disparities><Manuscripts><Maturity-Onset Diabetes Mellitus><Mentors><Mentorship><Minority Groups><Minority People><Minority Population><Minority individual><Mitigate health disparities><Modeling><NIDDM><NIH><National Institutes of Health><Native American group><Native American individual><Native American people><Native American population><Native Americans><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Participant><Patient Satisfaction><Patients><Physicians><Population><Postdoc><Postdoctoral Fellow><Preservice teacher><Prevalence><Principal Investigator><Process><Productivity><R & D><R&D><Race><Races><Recording of previous events><Reduce health disparities><Research><Research Associate><Research Career Program><Research Personnel><Researchers><Science><Self Efficacy><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Surgeon><System><T2 DM><T2D><T2DM><Testing><Training><Training Programs><Translational Research><Translational Science><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Underrepresented Groups><Underrepresented Populations><United States Department of Health and Human Services><United States Dept. of Health and Human Services><United States National Institutes of Health><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Writing><academic pathway><academic preparation><academic readiness><academic standard><adult onset diabetes><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><career><career advancement><career development><career fair><career networking><career transition><circulatory system><cohort><design><designing><developmental><disabled><disadvantaged background><disparity in care><disparity in health care><early-career faculty><educational standard><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><evidence base><faculty mentor><future faculty><health care disparity><health care inequality><health care inequity><high blood pressure><histories><homes><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><innovate><innovation><innovative><journal article><ketosis resistant diabetes><kids><marginalized background><maturity onset diabetes><medical college><medical schools><member><post-doc><post-doctoral><post-doctoral trainee><pre-service teacher><primary care provider><professional networking><programs><providers from primary care><providers of primary care><racial><racial background><racial minority group><racial minority individual><racial minority people><racial minority population><racial origin><recruit><research and development><research associates><school of medicine><skills><speed networking><student teacher><success><summer institute><translation research><translational investigation><type 2 DM><type II DM><type two diabetes><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joann Trejo

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 58/100

Training-friendly

Solid budget

Very recent

Active award

$342,360

FY 2026

Project Title

UCSD Future Faculty of Cardiovascular Sciences (FOCUS)

Grant Number:

5R25HL145817-08

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/8/2019

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract A diverse U.S. biomedical research workforce is essential for developing innovation in basic, translational and clinical research and healthcare and is necessary for improving the nation’s health. The NIH has identified key issues contributing to the disproportionate representation of under...

Research Terms

<0-11 years old><Academic skills><Adult-Onset Diabetes Mellitus><African American group><African American individual><African American people><African American population><African Americans><American><American Heart Association><Applications Grants><Area><Award><Basic Research><Basic Science><Biomedical Research><California><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Career Mobility><Caring><Categories><Censuses><Child><Child Youth><Children (0-21)><Client satisfaction><Clinical Research><Clinical Study><Communication><Data><Decrease health disparities><Department of Health and Human Services><Development><Development and Research><Diagnosis><Disparities><Disparity><EXTMR><Education><Educational aspects><Ethnic Origin><Ethnicity><Extramural><Extramural Activities><Faculty><Fellowship Program><Fostering><Frequencies><Funding><Future Teacher><Goals><Grant><Grant Proposals><Health><Health Care><Health disparity mitigation><Health disparity reduction><Heart Vascular><High Prevalence><Hispanic Americans><History><Home><Hypertension><Individual><Individuals from minority><Individuals of minority><Institution><Insurance><Investigators><K-Awards><K-Series Research Career Programs><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leadership><Lower health disparities><Manuscripts><Maturity-Onset Diabetes Mellitus><Mentors><Mentorship><Minority Groups><Minority People><Minority Population><Minority individual><Mitigate health disparities><Modeling><NIDDM><NIH><National Institutes of Health><Native American group><Native American individual><Native American people><Native American population><Native Americans><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Participant><Patient Satisfaction><Patients><Physicians><Population><Postdoc><Postdoctoral Fellow><Preservice teacher><Prevalence><Principal Investigator><Process><Productivity><R & D><R&D><Race><Races><Recording of previous events><Reduce health disparities><Research><Research Associate><Research Career Program><Research Personnel><Researchers><Science><Self Efficacy><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Surgeon><System><T2 DM><T2D><T2DM><Testing><Training><Training Programs><Translational Research><Translational Science><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Underrepresented Groups><Underrepresented Populations><United States Department of Health and Human Services><United States Dept. of Health and Human Services><United States National Institutes of Health><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Writing><academic pathway><academic preparation><academic readiness><academic standard><adult onset diabetes><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><career><career advancement><career development><career fair><career networking><career transition><circulatory system><cohort><design><designing><developmental><disabled><disadvantaged background><disparity in care><disparity in health care><early-career faculty><educational standard><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><evidence base><faculty mentor><future faculty><health care disparity><health care inequality><health care inequity><high blood pressure><histories><homes><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><innovate><innovation><innovative><journal article><ketosis resistant diabetes><kids><marginalized background><maturity onset diabetes><medical college><medical schools><member><post-doc><post-doctoral><post-doctoral trainee><pre-service teacher><primary care provider><professional networking><programs><providers from primary care><providers of primary care><racial><racial background><racial minority group><racial minority individual><racial minority people><racial minority population><racial origin><recruit><research and development><research associates><school of medicine><skills><speed networking><student teacher><success><summer institute><translation research><translational investigation><type 2 DM><type II DM><type two diabetes><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CRYSTAL WILEY CENE

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 58/100

Training-friendly

Solid budget

Very recent

Active award

$340,990

FY 2026

Project Title

UCSF Research in Implementation Science for Equity (RISE)

Grant Number:

5R25HL126146-12

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/15/2014

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT/SUMMARY There is a well-known gap between what we know can optimize health and healthcare and what happens in everyday practice. Implementation science (ImS) holds promise for generating new knowledge to close this gap. ImS is especially important for addressing health inequities which resu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alicia Fernandez

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 58/100

Training-friendly

Solid budget

Very recent

Active award

$340,990

FY 2026

Project Title

UCSF Research in Implementation Science for Equity (RISE)

Grant Number:

5R25HL126146-12

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/15/2014

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT/SUMMARY There is a well-known gap between what we know can optimize health and healthcare and what happens in everyday practice. Implementation science (ImS) holds promise for generating new knowledge to close this gap. ImS is especially important for addressing health inequities which resu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARGARET Anne HANDLEY

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 58/100

Training-friendly

Solid budget

Very recent

Active award

$340,990

FY 2026

Project Title

UCSF Research in Implementation Science for Equity (RISE)

Grant Number:

5R25HL126146-12

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/15/2014

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT/SUMMARY There is a well-known gap between what we know can optimize health and healthcare and what happens in everyday practice. Implementation science (ImS) holds promise for generating new knowledge to close this gap. ImS is especially important for addressing health inequities which resu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Carlos Jose Rodriguez

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 58/100

Training-friendly

Solid budget

Very recent

Active award

$318,882

FY 2026

Project Title

Mechanisms of cardiovascular disease

Grant Number:

5T32HL144456-08

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

1/1/2019

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

This is an application for the first competing renewal of a Ruth L. Kirschstein Institutional National Research Service Award (T32) entitled Mechanisms of Cardiovascular Disease. Building on the long tradition of NIH-sponsored cardiovascular research training at the Albert Einstein College of Medici...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nicholas E Sibinga

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 58/100

Training-friendly

Solid budget

Very recent

Active award

$318,882

FY 2026

Project Title

Mechanisms of cardiovascular disease

Grant Number:

5T32HL144456-08

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

1/1/2019

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

This is an application for the first competing renewal of a Ruth L. Kirschstein Institutional National Research Service Award (T32) entitled Mechanisms of Cardiovascular Disease. Building on the long tradition of NIH-sponsored cardiovascular research training at the Albert Einstein College of Medici...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LAURA HSI KWONG

UNIVERSITY OF CALIFORNIA BERKELEY, BERKELEY, CA

Good lead · 56/100

Likely hiring

Very recent

Active award

$230,526

FY 2026

Project Title

Understanding heat stress and adverse health outcomes in vulnerable populations in Bangladesh: Can we move the needle by designing low-cost, feasible and culturally acceptable interventions?

Grant Number:

5R01ES035910-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/2/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY During the last two decades, nearly half a million people died each year from heat-related causes; climate change is expected to exacerbate the burden of adverse health outcomes. Heat stress has been associated with an increase in all-cause mortality, cardiovascular disease and morta...

Research Terms

<21+ years old><Adult><Adult Human><Adverse effects><Affect><Age><Air Conditioning><Airway infections><Asia><Bangladesh><Biological Markers><Blood Pressure><Capital><Cardiac Chronotropism><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cessation of life><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Communities><Country><DALY><Death><Death Rate><Diabetes Mellitus><Disease><Disorder><Economic Income><Economical Income><Effectiveness><Effectiveness of Interventions><Elderly><Equity><Event><Face><Fatigue><Fe element><Frequencies><Gender><Goals><Health><Health Inequity><Heart Rate><Heart Vascular><Heat Stress><Heterogeneity><Home><Household><Housing><Hypertension><Income><Individual><Inequalities in Health><Inequities in Health><Inequity><Infrastructure><Intervention><Iron><Jobs><Kidney><Kidney Urinary System><Lack of Energy><Low Income Population><Low income><Low income group><Lower Respiratory Tract Infection><Lower respiratory infection><Mental Health><Mental Hygiene><Modeling><Modification><Morbidity><Morbidity - disease rate><Needles><Occupations><Outcome><Patient Self-Report><Persons><Phase><Population><Productivity><Professional Positions><Psychological Health><Randomized, Controlled Trials><Recommendation><Research><Respiratory Disease><Respiratory Infections><Respiratory System Disease><Respiratory System Disorder><Respiratory Tract Infections><Risk><Risk Factors><Self-Report><Severities><Slum><Subgroup><Technology><Temperature><Testing><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vulnerable Populations><acceptability and feasibility><adulthood><advanced age><adverse pregnancy outcome><ages><assess effectiveness><behavior change><bio-markers><biologic marker><biomarker><cardiovascular disorder><cardiovascular health><chronic airway disease><chronic kidney disease><chronic respiratory disease><circulatory system><climate change><climatic changes><co-morbid><co-morbidity><comorbidity><computer based prediction><cost><cost effective><cost effective intervention><cost effectiveness><death risk><design><designing><determine effectiveness><diabetes><disability-adjusted life years><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><examine effectiveness><experience><experiment><experimental research><experimental study><experiments><extreme heat><faces><facial><geriatric><global climate change><health equity><health inequalities><high blood pressure><high risk><home test><home-based test><homes><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><incomes><intervention cost><low income individual><low income people><model building><morbidity rate><mortality><mortality rate><mortality risk><predictive modeling><pregnant><prevent><preventing><primary outcome><randomized control trial><renal><respiratory><secondary outcome><senior citizen><sex><vulnerable group><vulnerable individual><vulnerable people>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jenifer Michelle Brown

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$192,896

FY 2026

Project Title

Cardiac Perfusion, Structure, and Function across the Primary Aldosteronism Spectrum

Grant Number:

5K23HL159279-05

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/15/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Heart failure with preserved ejection fraction (HFpEF) is a growing epidemic associated with multiple comorbidities, including hypertension. In part because of its heterogeneity, clinical trials in HFpEF have been largely disappointing to date, though the NHLBI-funded TOPCAT...

Research Terms

<21+ years old><Adrenal Glands><Adrenals><Adult><Adult Human><Advisory Committees><Aldosterone><Aldosterone Receptor><Aldosteronism><Ammonia><Angiotensin-Forming Enzyme><Angiotensinogenase><Atherosclerosis Risk in Communities><Award><Biological><Biology><Biostatistical Methods><Blood Pressure><Blood Vessels><Blood capillaries><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Muscle Cells><Cardiac Myocytes><Cardiocyte><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell-Extracellular Matrix><Characteristics><Chronic><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Research><Clinical Study><Clinical Trials><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Cross Sectional Analysis><Data><Dedications><Development><Development Plans><Diabetes Mellitus><Diastolic heart failure><Disease Outcome><Drugs><Dysfunction><ECM><EEF2><EEF2 gene><EF2><Echocardiogram><Echocardiography><Endothelium><Epidemic><Epidemiologic Methodology><Epidemiologic Methods><Epidemiologic research methodology><Epidemiologic research methods><Epidemiological Methods><Epidemiological Techniques><Epidemiology><Essential Hypertension><Exclusion><Extracellular Matrix><Fibrosis><Functional Imaging><Functional disorder><Funding><General Population><General Public><Goals><HF with preserved ejection fraction><HFpEF><Heart><Heart Diseases><Heart Muscle Cells><Heart Vascular><Heart failure><Heart myocyte><Heterogeneity><High Prevalence><Hormonal><Hospital Admission><Hospitalization><Hyperaldosteronism><Hypertension><Imaging Device><Imaging Instrument><Imaging Procedures><Imaging Technics><Imaging Techniques><Imaging Tool><Industry><Inflammation><Intervention><Investigation><Involuntary Muscle><Ischemia><Kidney><Kidney Urinary System><LV remodeling><Left Ventricular Remodeling><Leiomyocyte><Measures><Mediating><Medication><Medicine><Mentors><Methods Epidemiology><Methods in epidemiology><Microvascular Dysfunction><Mineralocorticoid Receptor><Myocardial><Myocardial perfusion><NHLBI><NIH><National Heart, Lung, and Blood Institute><National Institutes of Health><Obesity><Outcome><Oxidative Stress><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pathogenicity><Pathologic><Pathway interactions><Patients><Perfusion><Pharmaceutical Preparations><Phenotype><Physicians><Physiologic Imaging><Physiopathology><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Precision therapeutics><Prevalence><Prevention><Production><Rad.-PET><Receptor Activation><Registries><Renin><Research><Risk><Risk Factors><Role><Scientist><Severities><Site><Smooth Muscle><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Spirolactone><Spironolactone><Structure><Symptoms><Syndrome><Task Forces><Techniques><Transthoracic Echocardiography><United States National Institutes of Health><Vascular Diseases><Vascular Disorder><Vascular Endothelium><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular blood supply><Ventricle Remodeling><Ventricular Cardiac Remodeling><Ventricular Dysfunction><Ventricular Myocardial Remodeling><Ventricular Remodeling><Verospirone><Work><adiposity><adulthood><advisory team><analyzing longitudinal><antagonism><antagonist><atherosclerosis risk><atherosclerotic coronary disease><atherosclerotic risk><biologic><blood supply><blood vessel disorder><capillary><cardiac failure><cardiac imaging><cardiac scanning><cardiomyocyte><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular effects><cardiovascular imaging><cardiovascular risk><cardiovascular risk factor><career><career development><chronic kidney disease><circulatory system><clinical epidemiology><clinical translation><clinically translatable><co-morbid><co-morbidity><cohort><comorbidity><coronary arterial disease><corpulence><design><designing><developmental><diabetes><drug/agent><endothelial dysfunction><epidemiologic><epidemiological><epidemiology research study><epidemiology study><epidemiology survey><eplerenone><heart disorder><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart imaging><heart scanning><heart sonography><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><idiopathic hypertension><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><insight><left ventricle remodeling><longitudinal analysis><malleable risk><microvascular complications><microvascular disease><modifiable risk><mortality><myocardial remodeling><novel><pathophysiology><pathway><patient population><patient response><patient specific response><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><physiological imaging><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><precision therapies><precision treatment><preserved ejection fraction heart failure><primary hypertension><prognostic><renal><response to therapy><response to treatment><responsive patient><skills><social role><suprarenal gland><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic response><therapy response><translational investigator><translational researcher><translational scientist><treatment response><treatment responsiveness><vascular><vascular dysfunction><vascular supply><vasculopathy>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jesse Chimezie Ikeme

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$190,836

FY 2026

Project Title

Assessing Patient-Centric Factors and Enhancing Risk Communication to Improve Treatment Persistence in Kidney and Cardiovascular Care

Grant Number:

5K23DK144712-02

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/15/2025

End Date:

3/31/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Sodium glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide 1 receptor agonists (GLP1RA) are two classes of medications poised to revolutionize chronic kidney disease (CKD) care after repeatedly demonstrating their ability to prevent cardiovascular disease (CVD) and CKD pr...

Research Terms

<21+ years old><ASCVD><Acceleration><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Agonist><Ambulatory Care Facilities><American Heart Association><Application Context><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Attitude><Benefits and Risks><Biometrics><Biometry><Biostatistics><CVD prevention><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Clinical Practice Guideline><Clinical Trials><Communication><Communities><Complex><Development><Diagnosis><Disease Progression><Drugs><Elements><Equation><Event><Foundations><GLP-1 receptor><GLP-I receptor><Goals><Health><Health Care Providers><Health Care Systems><Health Personnel><Health Services><Health system><Heart Vascular><Heart failure><Hospital Admission><Hospitalization><Individual><Individualized risk prediction><Integrated Health Care Systems><International><Intervention><Interview><Joints><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Knowledge><Lipids><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medication><Mentors><Metabolic><Metabolic syndrome><Methods><Morbidity><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Organ><Outpatient Clinics><Patient Care><Patient Care Delivery><Patient Compliance><Patients><Persons><Pharmaceutical Preparations><Polypharmacy><Population><Predicting Risk><Preventative treatment><Prevention><Preventive><Preventive treatment><Process><Provider><Publishing><Reporting><Risk><Risk Estimate><Risk Factors><Risk Reduction><SGLT 2 inhibitor><SGLT2i><San Francisco><Slow-Onset Diabetes Mellitus><Socioeconomically disadvantaged><Sodium glucose co-transporter 2 inhibitor><Specialist><Specialty><Stable Diabetes Mellitus><Structure><T2 DM><T2D><T2DM><Therapeutic><Time><Translating><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Veterans><Veterans Health Administration><Veterans Health Affairs><Weight><Work><access to health care><accessibility of health care><accessibility to health care><adult onset diabetes><adulthood><atheromatosis><atherosclerosis risk><atherosclerotic disease><atherosclerotic risk><atherosclerotic vascular disease><cardiac disease prevention><cardiac failure><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><care coordination><care delivery><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical practice and guidelines><co-morbid><co-morbidity><communication aid><comorbidity><contextual factors><coordinating care><cost><developmental><drug/agent><experience><forecasting risk><frailty><glucagon-like peptide-1 receptor><health and care delivery><health care access><health care availability><health care delivery><health care personnel><health care service access><health care service availability><health care worker><health delivery systems><health provider><health services delivery><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><high risk><high risk group><high risk individual><high risk people><high risk population><implementation framework><implementation research framework><implementation science><implementation science framework><improved><innovate><innovation><innovative><insight><integrated health system><integrated system of care><ketosis resistant diabetes><maturity onset diabetes><medical care providers><medical personnel><medical specialties><mortality><new approaches><novel><novel approaches><novel strategies><novel strategy><old age><participant enrollment><patient adherence><patient clinician engagement><patient clinician interaction><patient clinician relationship><patient cooperation><patient doctor engagement><patient doctor interaction><patient doctor relationship><patient enrollment><patient physician engagement><patient physician interaction><patient physician relationship><patient provider engagement><patient provider interaction><patient provider relationship><personalized risk prediction><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><prevent><preventing><primary care clinic><primary care provider><primary care setting><providers from primary care><providers of primary care><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><renal><risk prediction><risk predictions><risk-reducing><side effect><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><stakeholder insights><stakeholder perspectives><tool><treatment provider><type 2 DM><type II DM><type two diabetes><weights>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bryant Shuey

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$189,463

FY 2026

Project Title

Lowering Cardiovascular Disease Among People with Opioid Use Disorder

Grant Number:

5K23DA062822-02

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/15/2025

End Date:

3/31/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Cardiovascular disease (CVD) is the leading cause of non-overdose death among people with opioid use dis- order (OUD). Hypertension (HTN) is a modifiable individual risk factor for CVD, with HTN medications reducing major adverse cardiovascular events (MACE) up to 25% compared to no treatme...

Research Terms

<21+ years old><Active Learning><Address><Adult><Adult Human><Affect><Attitude><Buprenorphine><CVD prevention><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Centers for Medicare and Medicaid Services><Chronic Disease><Chronic Illness><Clinical><Comprehensive Health Care><Cooperative Learning><Cox Proportional Hazards Models><Data><Data Files><Data Systems><Development Plans><Development and Research><Diabetes Mellitus><Diagnosis><Disease Management><Disorder Management><Drug usage><Drugs><Evaluation><Event><Experiential Learning><Face><Future><Goals><Health><Health Care Financing Administration><Health Services><Health Services Evaluation><Health Services Research><Heart Vascular><High Prevalence><Home><Hyperlipemia><Hyperlipidemia><Hypertension><IT Systems><Improve Access><Individual><Information Systems><Information Technology Systems><Intervention><Interview><Investigation><Investigators><K12><K12 Award><K12 Mechanism><K12 Program><Link><Literature><Managed Care><Medicaid><Medical><Medical Care Research><Medication><Mentored Clinical Scientist Development Program><Mentors><Methodology><Methods><Modeling><NHLBI><NIDA><National Heart, Lung, and Blood Institute><National Institute of Drug Abuse><National Institute on Drug Abuse><Outcome><Patient-Centered Care><Patients><Persons><Pharmaceutical Preparations><Policies><Policy Research><Population><Predisposition><Prevalence><Probability><Provider><Public Health><Qualitative Methods><Qualitative Research><Quasi-experiment><Quasi-experimental analysis><Quasi-experimental approach><Quasi-experimental design><Quasi-experimental methods><Quasi-experimental research><Quasi-experimental study><Quasi-experimental technique><R & D><R&D><Research><Research Personnel><Researchers><Risk><Risk Factors><Risk Reduction><Sampling><Services><Stigmatization><Structure><Substance Use Disorder><Susceptibility><Time><Tobacco><Tobacco Consumption><Tobacco use><Training><United States Centers for Medicare and Medicaid Services><United States Health Care Financing Administration><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><addiction><addictive disorder><adulthood><adverse consequence><adverse outcome><behavioral health><cardiac disease prevention><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><care coordination><career><career development><chronic disorder><circulatory system><cohort><comprehensive care><coordinating care><diabetes><differences in health><drug use><drug/agent><experience><faces><facial><hazard><health and care delivery><health care delivery><health care quality><health delivery systems><health difference><health services delivery><high blood pressure><high risk group><high risk individual><high risk people><high risk population><homes><hyperpiesia><hyperpiesis><hypertension treatment><hypertensive disease><hypertensive disorder><improved><innovate><innovation><innovative><insight><integrated care><integrated health care><integrated model of care><mortality><non-drug><nondrug><novel><opiate use disorder><opioid treatment program><opioid use disorder><overdose death><overdose fatalities><patient barriers><patient-level barriers><payment><prevent><preventing><primary care provider><programs><provider barriers><provider-level barriers><providers from primary care><providers of primary care><psychostimulant use><qualitative reasoning><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><research and development><risk-reducing><services research><stimulant use><substance use and disorder><tobacco product use><tool><use of stimulants>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Zheng Wang

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$165,639

FY 2026

Project Title

Multiomics analysis of the microbiome and subclinical cardiovascular disease in HIV infection

Grant Number:

5K01HL169019-03

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY This K01 Career Development Award application proposes a multidisciplinary 5-year training program to provide the candidate, Dr. Zheng Wang, with the experience and resources necessary to launch a successful career as an independent investigator. The training plan, developed closely ...

Research Terms

<16S RNA sequencing><16S RNAseq><16S gene sequencing><16S rDNA amplicon sequencing><16S rRNA DNA sequencing><16S rRNA amplicon sequencing><16S rRNA gene amplicon sequencing><16S rRNA gene sequencing><16S rRNA genomic profiling><16S rRNA sequencing><16S ribosomal RNA gene sequencing><16S ribosomal RNA sequencing><16S seq><16S sequencing><16s rRNA seq><4E-BP1><ABCD-3><AIDS Virus><ASCVD><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Active Follow-up><Advisory Committees><Affect><Algorithms><Anti-HIV Positivity><Area><Arterial Fatty Streak><Atheroma><Atheromatous><Atheromatous degeneration><Atheromatous plaque><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Bacteria><Bacterial Infections><Biological Markers><Blood Serum><Blood Vessels><Body Tissues><Buccal Cavity><Buccal Cavity Head and Neck><C fusiforme><C. fusiforme><C3Xkine><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CX3CL1><CX3CL1 gene><CXC3><CXC3C><Cardiac><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Carotid Artery Plaques><Carotid Atheroscleroses><Carotid Atherosclerotic Disease><Cavitas Oris><Cell Count><Cell Number><Ch'i><Cohort Studies><Corynebacterium fusiforme><Data><Development><Drugs><EIF4EBP1><EIF4EBP1 gene><F fusiformis><F nucleatum><F nucleatus><F. fusiformis><F. nucleatum><F. nucleatus><Functional Metagenomics><Fusiformis fusiformis><Fusiformis nucleatus><Fusobacterium><Fusobacterium nucleatum><GI microbiome><GI microbiota><Gastrointestinal microbiota><Gram-Negative Anaerobic Bacteria><HAART><HIV><HIV Infections><HIV Positive><HIV Positivity><HIV Seroconversion><HIV Seropositivity><HIV antibody positive><HIV disease status><HIV individuals><HIV infected individuals><HIV infected persons><HIV infection status><HIV load><HIV people><HIV plasma viral load><HIV positive individuals><HIV positive people><HIV serostatus><HIV status><HIV viral burden><HIV viral infection><HIV viral load><HIV virus infection><HIV+><HIV-1><HIV-1 infection><HIV-1 load><HIV-1 viral burden><HIV-1 viral load><HIV-I><HIV1><HIV1 infection status><HIV1 status><HTLV-III Seroconversion><HTLV-III Seropositivity><Heart Vascular><Highly Active Antiretroviral Therapy><Histidine><Human Immunodeficiency Virus Type 1><Human Immunodeficiency Virus-1><Human Immunodeficiency Viruses><Human immunodeficiency virus 1><Immunity><Individual><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Inflammation><Inflammatory><Intermediary Metabolism><Intervention><Investigators><K-Awards><K-Series Research Career Programs><LAV-HTLV-III><Life Expectancy><Link><Lymphadenopathy-Associated Virus><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Mentors><Metabolic Processes><Metabolism><Metagenomics><Morbidity><Mouth><Mouth microbiome><Myocardial><Myocardial Diseases><Myocardial Disorder><Myocardial depression><Myocardial dysfunction><Myocardiopathies><NMR Imaging><NMR Tomography><Nuclear Magnetic Resonance Imaging><Oral><Oral cavity><Oscines><PLWH><PWH><Participant><Pathology><Patients><Persons><Pharmaceutical Preparations><Physiology><Play><Population><Predicting Risk><Prevention><Prize><Proteins><Proteome><Proteomics><Qi><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Career Program><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Risk Factors><Role><SCYD1><Serum><Shotgun Sequencing><Shotguns><Songbirds><Source><Sphaerophorus><T4 Cells><T4 Lymphocytes><Task Forces><The Multi-center AIDS Cohort Study><The Multicenter AIDS Cohort Study><Therapeutic><Tissues><Training><Training Programs><Virus-HIV><Woman><Women's Interagency HIV Study><Work><Zeugmatography><active followup><advisory team><alter microbiome><analyze microbiome><atheromatosis><atherosclerosis plaque><atherosclerotic disease><atherosclerotic lesions><atherosclerotic plaque><atherosclerotic vascular disease><bacteria in the gut><bacteria infection><bacteria pathogen><bacterial disease><bacterial pathogen><bio-markers><biologic marker><biomarker><cardiac MRI><cardiac dysfunction><cardiac magnetic resonance imaging><cardiovascular disease epidemiology><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder epidemiology><cardiovascular disorder risk><cardiovascular epidemiology><career><carotid plaque><circulatory system><cohort><cohort research study><cohort survey><commensal community><commensal microbiome><commensal species><developmental><digestive tract microbiome><drug/agent><enteric microbial community><enteric microbiome><enteric microbiota><experience><follow up><follow-up><followed up><followup><forecasting risk><forest><gastrointestinal microbial flora><gastrointestinal microbiome><gut bacteria><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiome><gut microbiota><gut microbiotic><gut microflora><gut-associated microbiome><heart dysfunction><highly active antiretroviral treatment><human flora><human immunodeficiency virus infection><human microbial communities><human microbiota><human microflora><human-associated microbial communities><human-associated microbiota><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><inflammation marker><inflammatory marker><intestinal biome><intestinal flora><intestinal microbiome><intestinal microbiota><intestinal microflora><intestinal tract microflora><life span><lifespan><men><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><metagenome sequencing><metagenomic sequencing><microbial><microbial consortia><microbial flora><microbiome><microbiome adaptation><microbiome alteration><microbiome analysis><microbiome perturbation><microbiota><microflora><mortality><multidisciplinary><multiomics><multiple omics><multispecies consortia><myocardium disease><myocardium disorder><novel><oral bacteria><oral flora><oral microbial community><oral microbiome><oral microbiota><oral microflora><panomics><pathogenic bacteria><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><plaques in atherosclerosis><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><prospective><resident commensals><risk prediction><risk predictions><saliva sample><salivary sample><segregation><shot gun><social role><song bird><ultrasound><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Maura Kepper

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$163,702

FY 2026

Project Title

K01 Career Development Award

Grant Number:

5K01HL167993-03

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The overarching goal of this candidate’s program of research is to overcome social and environmental barriers to promote behavior change and cardiovascular health. The focus on this application is rural patients, since cardiovascular disease (CVD) prevalence is 40% higher among rura...

Research Terms

<21+ years old><Active Follow-up><Adult><Adult Human><American Heart Association><Award><Awareness><BMI><BMI percentile><BMI z-score><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body mass index><Cardiac health><Cardiovascular Diseases><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Chronic Disease><Chronic Illness><Clinic><Clinic Visits><Collaborations><Communities><Community Health Aides><Conditioning Therapy><Counseling><County><Data><Diabetes Mellitus><Eating><Effectiveness><Electronic Health Record><Evaluation><Federally Qualified Health Center><Feedback><Food Intake><Foundations><Future><Goals><HRSA><Health><Health Care><Health Care Team><Health Food><Health Resources and Services Administration><Health behavior><Health behavior and outcomes><Heart health><Institution><International><Interview><Investigators><K-Awards><K-Series Research Career Programs><K12><K12 Award><K12 Mechanism><K12 Program><Leadership><Life><Maps><Medical Care Team><Mentored Clinical Scientist Development Program><Mentors><Methodology><Methods><Missouri><Motivation><Multiple Partners><Nutritious food><Obesity><Overweight><Patient Care><Patient Care Delivery><Patients><Physical activity><Pragmatic clinical trial><Prevalence><Process><QOC><Quality of Care><Quetelet index><Randomization trial><Recommendation><Reporting><Research><Research Career Program><Research Methodology><Research Methods><Research Personnel><Research Resources><Researchers><Resources><Rural><Rural Community><Rural Health><Science><Structure><Testing><Training><United States><United States Health Resources and Services Administration><Visual><Work><active followup><adiposity><adulthood><behavior change><behavior intervention><behavioral intervention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><care for patients><care of patients><career><career development><caring for patients><chronic care model><chronic disorder><community health worker><corpulence><design><designing><diabetes><digital health><dissemination science><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evidence base><experience><follow up><follow-up><followed up><followup><health care quality><health related behavior><healthy food><healthy weight><implementation protocol><implementation science><improved><member><mortality><obese patients><obesity management><participant engagement><patient centered><patient engagement><patient oriented><patients with obesity><prevent><preventing><primary care team><programs><randomized trial><recruit><research and methods><rural area><rural clinic><rural dwellers><rural health clinic><rural locality><rural location><rural patients><rural place><rural region><rural resident><rural setting><skills><social><success><technology intervention><technology-based interventions><technology-enabled interventions><technology-focused interventions><tool>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ariana Stickel

SAN DIEGO STATE UNIVERSITY, SAN DIEGO, CA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$153,990

FY 2026

Project Title

Risk Factors for Alzheimer's Disease Among Latinos: Relationships Between Cardiovascular Disease Risk, Acculturation, Small Vessel Disease, and Alzheimer's Biomarkers

Grant Number:

5K08AG075351-05

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Latinos/as are a large and growing segment of the United States older adult population and are at increased risk for Alzheimer’s disease and related dementias (ADRDs) compared to non-Latino/a Whites. Evidence suggests that Latinos/as are particularly susceptible to ADRD in the presen...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Cristina A. F. Román

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$140,808

FY 2026

Project Title

Healthcare Factors and Cardiovascular Risk Influences on Accelerated Brain Aging and Disability in Hispanic Persons with Multiple Sclerosis

Grant Number:

5K23MD019232-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/23/2023

End Date:

3/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

This is a mixed methods study examining healthcare factors, medical comorbidities [i.e., cardiovascular risk factors (CRF)], and accelerated brain aging in Hispanic persons with multiple sclerosis (H-pwMS). This Career Development Award (CDA) will provide the necessary support for Dr. Cristina Román...

Research Terms

<21+ years old><Acceleration><Adult><Adult Human><Age><Aging><Amentia><Applications Grants><Biological><Biological Markers><Brain><Brain Nervous System><Brain imaging><C 2a><C2a><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Chronology><Clinical><Communities><Critical Care><Data><Decrease health disparities><Dementia><Development><Disability Assessment><Disability Determination><Disability Evaluation><Disease><Disease Progression><Disorder><Disparities><Disparity><Doctor of Philosophy><Early Intervention><Encephalon><Ensure><Espanol><Foundations><Goals><Grant Proposals><Groups at risk><Health><Health Care><Health disparity mitigation><Health disparity reduction><Heart Vascular><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Individual><Infrastructure><Intervention><Investigation><Investigators><K-Awards><K-Series Research Career Programs><Knowledge><Lived experience><Lived experiences><Longitudinal Studies><Longitudinal Surveys><Lower health disparities><MR Imaging><MR Tomography><MRI><MRIs><MS patient><Machine Learning><Magnetic Resonance Imaging><Manuscripts><Measures><Medical><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Mentorship><Methods><Mission><Mitigate health disparities><Modeling><NCMHD><NIH><NIMHD><NMR Imaging><NMR Tomography><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Nerve Degeneration><Nervous System Diseases><Nervous System Disorder><Neurologic><Neurologic Disorders><Neurological><Neurological Disorders><Neuron Degeneration><Neuropsychologies><Neuropsychology><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Nuclear Magnetic Resonance Imaging><Outcome><Participant><People at risk><Persons><Persons at risk><Ph.D.><PhD><Population><Populations at Risk><Prognosis><Reduce health disparities><Research><Research Career Program><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Factors><Sampling><Scientific Advances and Accomplishments><Spanish><Stress><Training><United States National Institutes of Health><Universities><Work><Writing><Zeugmatography><access to health care><accessibility of health care><accessibility to health care><adulthood><age associated alterations><age associated changes><age correlated alterations><age correlated changes><age dependent alterations><age dependent changes><age induced alterations><age induced changes><age related alterations><age related changes><age specific alterations><age specific changes><aged brain><ages><aging associated alterations><aging associated changes><aging brain><aging correlated alterations><aging correlated changes><aging dependent alterations><aging dependent changes><aging induced alterations><aging induced changes><aging related alterations><aging related changes><aging specific alterations><aging specific changes><alterations with age><bio-markers><biologic><biologic marker><biomarker><brain health><brain visualization><brain volume><cardiovascular risk><cardiovascular risk factor><career><changes with age><circulatory system><co-morbid><co-morbidity><comorbidity><complement 2a><complement C2a><complement C2a fragment><design><designing><developmental><disability><disparity in health><effective intervention><experience><functional outcomes><health care access><health care availability><health care management><health care quality><health care service access><health care service availability><health disparity><health management><high risk><improved><long-term study><longitudinal outcome studies><longitudinal research study><machine based learning><medical college><medical schools><mortality><multiple sclerosis patient><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neurological disease><neuronal degeneration><neuropsychologic><offspring><patients with MS><patients with multiple sclerosis><people with Multiple sclerosis><premature><prematurity><profound disability><recruit><school of medicine><scientific accomplishments><scientific advances><serious disability><severe disability><skills><stem><virtual>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LAURA HSI KWONG

UNIVERSITY OF CALIFORNIA BERKELEY, BERKELEY, CA

Good lead · 56/100

Likely hiring

Very recent

Active award

$134,163

FY 2026

Project Title

Understanding heat stress and adverse health outcomes in vulnerable populations in Bangladesh: Can we move the needle by designing low-cost, feasible and culturally acceptable interventions?

Grant Number:

3R01ES035910-03S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/2/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY During the last two decades, nearly half a million people died each year from heat-related causes; climate change is expected to exacerbate the burden of adverse health outcomes. Heat stress has been associated with an increase in all-cause mortality, cardiovascular disease and morta...

Research Terms

<21+ years old><Adult><Adult Human><Adverse effects><Affect><Age><Air Conditioning><Airway infections><Asia><Bangladesh><Biological Markers><Blood Pressure><Capital><Cardiac Chronotropism><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cessation of life><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Communities><Country><DALY><Death><Death Rate><Diabetes Mellitus><Disease><Disorder><Economic Income><Economical Income><Effectiveness><Effectiveness of Interventions><Elderly><Equity><Event><Face><Fatigue><Fe element><Frequencies><Gender><Goals><Health><Health Inequity><Heart Rate><Heart Vascular><Heat Stress><Heterogeneity><Home><Household><Housing><Hypertension><Income><Individual><Inequalities in Health><Inequities in Health><Inequity><Infrastructure><Intervention><Iron><Jobs><Kidney><Kidney Urinary System><Lack of Energy><Low Income Population><Low income><Low income group><Lower Respiratory Tract Infection><Lower respiratory infection><Mental Health><Mental Hygiene><Modeling><Modification><Morbidity><Morbidity - disease rate><Needles><Occupations><Outcome><Patient Self-Report><Persons><Phase><Population><Productivity><Professional Positions><Psychological Health><Randomized, Controlled Trials><Recommendation><Research><Respiratory Disease><Respiratory Infections><Respiratory System Disease><Respiratory System Disorder><Respiratory Tract Infections><Risk><Risk Factors><Self-Report><Severities><Slum><Subgroup><Technology><Temperature><Testing><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vulnerable Populations><acceptability and feasibility><adulthood><advanced age><adverse pregnancy outcome><ages><assess effectiveness><behavior change><bio-markers><biologic marker><biomarker><cardiovascular disorder><cardiovascular health><chronic airway disease><chronic kidney disease><chronic respiratory disease><circulatory system><climate change><climatic changes><co-morbid><co-morbidity><comorbidity><computer based prediction><cost><cost effective><cost effective intervention><cost effectiveness><death risk><design><designing><determine effectiveness><diabetes><disability-adjusted life years><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><examine effectiveness><experience><experiment><experimental research><experimental study><experiments><extreme heat><faces><facial><geriatric><global climate change><health equity><health inequalities><high blood pressure><high risk><home test><home-based test><homes><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><incomes><intervention cost><low income individual><low income people><model building><morbidity rate><mortality><mortality rate><mortality risk><predictive modeling><pregnant><prevent><preventing><primary outcome><randomized control trial><renal><respiratory><secondary outcome><senior citizen><sex><vulnerable group><vulnerable individual><vulnerable people>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jelena Mustra Rakic

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$127,168

FY 2026

Project Title

Modeling the Effect of Apolipoprotein LI Risk Variants on CVD Risk in African American E-cigarette Users Using Human Induced Pluripotent Stem-Cell-Derived Endothelial Cells

Grant Number:

1K99HL183741-01

Activity Code:

K99

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT African American individuals face a disproportionately higher risk of tobacco-related cardiovascular diseases (CVD) than other races, a disparity not fully explained by traditional and socioeconomic risk factors. Despite lacking approval from the U.S. Food and Drug Administr...

Research Terms

<(TNF)-α><Address><Adverse effects><African American><African American group><African American individual><African American people><African American population><African Americans><Afro American><Afroamerican><After Care><After-Treatment><Aftercare><Apolipoproteins><Apoplexy><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Beta Proprotein Interleukin 1><Blood Vessels><Brain Vascular Accident><CCL2><CCL2 gene><CD183><CKR-L2><CMKAR3><CRG-2><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><CXCL10><CXCL10 gene><CXCR3><CXCR3 gene><Cachectin><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Models><Cardiovascular Organ System><Cardiovascular system><Cas nuclease technology><Cell Communication and Signaling><Cell Culture Techniques><Cell Function><Cell Line><Cell Physiology><Cell Process><Cell Signaling><CellLine><Cellular Function><Cellular Physiology><Cellular Process><Cellular injury><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chemokine (C-X-C Motif) Receptor 3><Chemokine, CC Motif, Ligand 2><Cigarette><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Communities><Computational Technique><Coronary Disease><Coronary heart disease><Development><Disease><Disease Management><Disorder><Disorder Management><Disparities><Disparity><Dysfunction><Electronic cigarette><Endothelial Cells><Endothelium><Exhibits><Exposure to><Face><Food and Drug Administration><Functional disorder><G Protein-Coupled Receptor 9><GPR9><Gene variant><Genes><Genetic Markers><Genotype><Goals><HPGF><Health><Heart Vascular><Hepatocyte-Stimulating Factor><History><Human><Hybridoma Growth Factor><IFI10><IFN-Gamma><IFN-beta 2><IFN-g><IFN-γ><IFNB2><IFNG><IFNγ><IL-1 beta><IL-1 β><IL-1-b><IL-1β><IL-6><IL1-Beta><IL1-β><IL1B Protein><IL1F2><IL1β><IL6 Protein><INP10><IP-10><IP10><IP10 Receptor><IP10-Mig receptor><IP10-R><Immune Interferon><Impairment><In Vitro><Inflammation Mediators><Inflammatory><Interferon Gamma><Interferon Type II><Interleukin 1beta><Interleukin-1 beta><Interleukin-1β><Interleukin-6><Intervention><Intracellular Communication and Signaling><Ischemic Stroke><Kidney><Kidney Diseases><Kidney Urinary System><Knowledge><Link><MCAF><MCP-1><MCP1><MGI-2><MOB-1><Macrophage-Derived TNF><Marketing><Menthol><Mentors><Mig Receptor><Mig-R><MigR><Modeling><Modern Man><Molecular><Molecular Target><Monocyte Chemoattractant Protein-1><Monocyte Chemotactic Protein-1><Monocyte Chemotactic and Activating Factor><Monocyte Chemotactic and Activating Protein><Monocyte Chemotactive and Activating Factor><Monocyte Secretory Protein JE><Monocyte-Derived TNF><Myeloid Differentiation-Inducing Protein><Nephropathy><Pathology><Pathway interactions><Pattern><Phase><Phenotype><Physiopathology><Plasmacytoma Growth Factor><Play><Polyunsaturated Fatty Acids><Population><Predisposition><Preinterleukin 1 Beta><Race><Races><Racial Group><Recording of previous events><Renal Disease><Research><Risk><Risk Factors><Risk-associated variant><Role><SCYA2><SCYB10><Safety><Sepsis><Signal Transduction><Signal Transduction Systems><Signaling><Smoker><Smoking><Strains Cell Lines><Stroke><Study models><Subcellular Process><Susceptibility><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Tobacco><Tobacco Consumption><Tobacco Industry><Tobacco use><Training><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><USFDA><United States Food and Drug Administration><Variant><Variation><Vascular Endothelial Cell><Work><Youth><Youth 10-21><allelic variant><biological signal transduction><brain attack><burden of disease><burden of illness><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular injury><cardiovascular risk><cardiovascular risk factor><cell culture><cell cultures><cell damage><cell injury><cellular damage><cerebral vascular accident><cerebrovascular accident><cigarette smoking><cigarette use><cigarette user><circulatory system><clinical relevance><clinically relevant><combustible cigarette><community marginalization><conventional cigarette><coronary disorder><cultured cell line><damage to cells><developmental><disease burden><disparity in health><e-cig><e-cig use><e-cig user><e-cigarette><e-cigarette use><e-cigarette user><ecig><ecig use><ecig user><ecigarette><ecigarette use><ecigarette user><electronic cigarette use><electronic cigarette user><endothelial dysfunction><faces><facial><gIP-10><gene biomarker><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genome editing><genomic editing><genomic variant><health disparity><hiPSC><high risk><high risk group><high risk individual><high risk people><high risk population><histories><human iPS><human iPSC><human induced pluripotent cell><human induced pluripotent stem cells><human inducible pluripotent stem cells><human inducible stem cells><iPS><iPSC><iPSCs><improved><in vitro Assay><in vivo><induced human pluripotent stem cells><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><inflammation marker><inflammatory marker><inflammatory mediator><injury to cells><injury to the vasculature><insight><interest><interferon beta 2><kidney disorder><lFN-Gamma><life-threatening COVID><life-threatening COVID-19><life-threatening SARS-CoV-2><life-threatening coronavirus disease><life-threatening coronavirus disease 2019><life-threatening severe acute respiratory syndrome coronavirus 2><lipid mediator><marginalized community><molecular biomarker><molecular marker><pathophysiology><pathway><post treatment><racial><racial background><racial origin><racial population><racial subgroup><renal><renal disorder><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><serious COVID><serious COVID-19><serious SARS-CoV-2><serious coronavirus disease><serious coronavirus disease 2019><serious severe acute respiratory syndrome coronavirus 2><severe COVID><severe COVID-19><severe COVID19><severe SARS-CoV-2><severe coronavirus disease><severe coronavirus disease 19><severe coronavirus disease 2019><severe severe acute respiratory syndrome coronavirus 2><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><stem cell approach><stem cell based approach><stem cell method><stem cell methodology><stem cell procedure><stem cell technique><stroked><strokes><tobacco company><tobacco product use><tobacco products><traditional cigarette><transcriptomics><trend><vaping><vascular><vascular endothelial dysfunction><vascular injury><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christine Kee Liu

PALO ALTO VETERANS INSTIT FOR RESEARCH, PALO ALTO, CA

Good lead · 56/100

Likely hiring

Very recent

Active award

$83,830

FY 2026

Project Title

Deprescribing Cardiovascular Medications among Persons with and without Alzheimer's Disease and Related Dementias in Long-Term Care

Grant Number:

3R01AG062568-04S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2019

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT The use of preventive cardiovascular medications among nursing home residents with Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) presents a clinical conundrum. On one hand, the majority of nursing home residents with AD/ADRD have a history of cardio...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD and related dementia><AD dementia><AD patients><AD related dementia><ADRD><Acetylsalicylic Acid><Address><Admission><Admission activity><Adult><Adult Human><Adverse Experience><Adverse event><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's patient><Alzheimers Dementia><Amentia><Analgesic Management><Anti-Hypertensive Agents><Anti-Hypertensive Drugs><Anti-Hypertensives><Anticoagulant Agents><Anticoagulant Drugs><Anticoagulants><Apoplexy><Aspirin><Atrial Fibrillation><Auricular Fibrillation><Bar Codes><Bleeding><Blood Platelets><Brain Vascular Accident><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Chronic><Clinical><Clinical Trials><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><D-Glucose><Data><Dementia><Descriptive Epidemiology><Dextrose><Disturbance in cognition><Dose><Drugs><Epidemiology><Event><Frequencies><Glucose><Goals><Grant><Heart Vascular><Hemorrhage><History><Hypotensive Agent><Hypotensive Drugs><Impaired cognition><Impairment><Incidence><Inpatients><Laboratories><Link><Long-Term Care><Marrow platelet><Measurement><Medicare/Medicaid><Medication><Medication Management><Mentors><Methods><Myocardial Infarct><Myocardial Infarction><Nursing Homes><Observation in research><Out-patients><Outcome><Outpatients><Paper><Patients><Persons><Pharmaceutical Preparations><Pharmacologic Management><Physical Function><Platelets><Population><Preventive><Primary Prevention><Primary Senile Degenerative Dementia><Process><Provider><Publications><Randomized, Controlled Trials><Recording of previous events><Regimen><Research><Risk><Science><Scientific Publication><Scientist><Secondary Prevention><Stroke><Structure><Thrombocytes><Uncertainty><Veterans Health Administration><Veterans Health Affairs><Work><above age 65><acute coronary syndrome><adulthood><adverse event risk><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><anti-hypertension><barcode><blood loss><blood thinner><brain attack><cardiac infarct><cardioprotectant><cardioprotection><cardioprotective><cardiovascular disorder><career><cerebral vascular accident><cerebrovascular accident><circulatory system><cognitive dysfunction><cognitive loss><cohort><conference><convention><coronary attack><coronary event><coronary infarct><coronary infarction><decision-making capacity><doubt><drug/agent><epidemiologic><epidemiological><extended care><functional outcomes><heart attack><heart infarct><heart infarction><high risk><histories><human old age (65+)><medication administration><medication therapy management><mortality><novel><nursing home><over 65 years><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><primary degenerative dementia><randomized control trial><senile dementia of the Alzheimer type><statistics><stroked><strokes><success><summit><symposia><symposium><thrombopoiesis inhibitor><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michelle Christina Odden

PALO ALTO VETERANS INSTIT FOR RESEARCH, PALO ALTO, CA

Good lead · 56/100

Likely hiring

Very recent

Active award

$83,830

FY 2026

Project Title

Deprescribing Cardiovascular Medications among Persons with and without Alzheimer's Disease and Related Dementias in Long-Term Care

Grant Number:

3R01AG062568-04S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2019

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT The use of preventive cardiovascular medications among nursing home residents with Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) presents a clinical conundrum. On one hand, the majority of nursing home residents with AD/ADRD have a history of cardio...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD and related dementia><AD dementia><AD patients><AD related dementia><ADRD><Acetylsalicylic Acid><Address><Admission><Admission activity><Adult><Adult Human><Adverse Experience><Adverse event><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's patient><Alzheimers Dementia><Amentia><Analgesic Management><Anti-Hypertensive Agents><Anti-Hypertensive Drugs><Anti-Hypertensives><Anticoagulant Agents><Anticoagulant Drugs><Anticoagulants><Apoplexy><Aspirin><Atrial Fibrillation><Auricular Fibrillation><Bar Codes><Bleeding><Blood Platelets><Brain Vascular Accident><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Chronic><Clinical><Clinical Trials><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><D-Glucose><Data><Dementia><Descriptive Epidemiology><Dextrose><Disturbance in cognition><Dose><Drugs><Epidemiology><Event><Frequencies><Glucose><Goals><Grant><Heart Vascular><Hemorrhage><History><Hypotensive Agent><Hypotensive Drugs><Impaired cognition><Impairment><Incidence><Inpatients><Laboratories><Link><Long-Term Care><Marrow platelet><Measurement><Medicare/Medicaid><Medication><Medication Management><Mentors><Methods><Myocardial Infarct><Myocardial Infarction><Nursing Homes><Observation in research><Out-patients><Outcome><Outpatients><Paper><Patients><Persons><Pharmaceutical Preparations><Pharmacologic Management><Physical Function><Platelets><Population><Preventive><Primary Prevention><Primary Senile Degenerative Dementia><Process><Provider><Publications><Randomized, Controlled Trials><Recording of previous events><Regimen><Research><Risk><Science><Scientific Publication><Scientist><Secondary Prevention><Stroke><Structure><Thrombocytes><Uncertainty><Veterans Health Administration><Veterans Health Affairs><Work><above age 65><acute coronary syndrome><adulthood><adverse event risk><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><anti-hypertension><barcode><blood loss><blood thinner><brain attack><cardiac infarct><cardioprotectant><cardioprotection><cardioprotective><cardiovascular disorder><career><cerebral vascular accident><cerebrovascular accident><circulatory system><cognitive dysfunction><cognitive loss><cohort><conference><convention><coronary attack><coronary event><coronary infarct><coronary infarction><decision-making capacity><doubt><drug/agent><epidemiologic><epidemiological><extended care><functional outcomes><heart attack><heart infarct><heart infarction><high risk><histories><human old age (65+)><medication administration><medication therapy management><mortality><novel><nursing home><over 65 years><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><primary degenerative dementia><randomized control trial><senile dementia of the Alzheimer type><statistics><stroked><strokes><success><summit><symposia><symposium><thrombopoiesis inhibitor><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mariana Xavier Byndloss

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

Good lead · 52/100

Likely hiring

Solid budget

Active award

$490,258

FY 2026

Project Title

Obesogenic diet-induced intestinal epithelium repair responses link dysbiosis and cardiovascular disease

Grant Number:

5R01DK131104-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/12/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY An obesogenic Western-style (HF) diet causes low-grade intestinal inflammation, intestinal microbiota imbalance, and an increased risk of cardiovascular disease. However, our knowledge about the pathways producing each of these different disease manifestations is incomplete, making i...

Research Terms

<21+ years old><ASCVD><Acceleration><Address><Adult><Adult Human><Aerobic><Affect><Amines><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Automobile Driving><Blood monocyte><Cardiac Diseases><Cardiac Disorders><Cardiovascular Diseases><Cessation of life><Choline><Chronic><Circulation><Coliform Bacilli><Colon><Complex><Data><Death><Development><Diet><Disease><Disorder><Enteric Bacteria><Enterobacteria><Enterobacteriaceae><Epithelial Cells><Event><Exposure to><GI microbiota><Gastrointestinal microbiota><Goals><Health><Heart Diseases><High Fat Diet><Hyperplasia><Hyperplastic><In Vitro><Inflammatory><Intermediary Metabolism><Intestinal><Intestinal Diseases><Intestinal Disorder><Intestines><Investigators><Knowledge><Link><Marrow monocyte><Mediating><Metabolic Processes><Metabolism><Modeling><Molecular><Mucosa><Mucosal Tissue><Mucous Membrane><Obesity><Oxides><Pathway interactions><Population><Production><Research Personnel><Researchers><Respiration><Role><Saturated Fatty Acids><Study models><Taxon><Testing><adiposity><adulthood><amine><atheromatosis><atherosclerosis risk><atherosclerotic disease><atherosclerotic risk><atherosclerotic vascular disease><bowel><bowel inflammation><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><colonic crypt><corpulence><day shift><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><driving><dysbacteriosis><dysbiosis><dysbiotic><enteric microbial community><enteric microbiota><epithelial repair><experiment><experimental research><experimental study><experiments><gastrointestinal microbial flora><gut community><gut dysbiosis><gut flora><gut inflammation><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiota><gut microbiotic><gut microflora><heart disorder><host-associated microbes><host-associated microbial communities><host-associated microbiota><host-associated microorganisms><in vivo><inflamed bowel><inflamed gut><inflamed intestine><innovate><innovation><innovative><insight><interest><intestinal epithelium><intestinal flora><intestinal inflammation><intestinal microbiota><intestinal microflora><intestinal tract microflora><intestine disease><intestine disorder><microbial><microbial imbalance><microbiota composition><mitochondrial dysfunction><monocyte><mouse model><murine model><night shift><night work><novel><obesigenic><obesity-promoting diet><obesogenic><obesogenic Western-style diet><obesogenic diet><obesogenic high fat diet><obesogenic western diet><pathway><pro-obesity diet><recruit><respiratory mechanism><response><shift work><shiftwork><social role>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrei Maiseyeu

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Good lead · 52/100

Likely hiring

Solid budget

Active award

$402,500

FY 2026

Project Title

Targets and targeting of immunometabolism in chronic PM2.5 exposure

Grant Number:

5R01ES033670-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/7/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary PM2.5 is a leading global risk factor for morbidity and mortality and is the leading environmental factor implicated in cardiovascular disease. Recent data suggest that PM2.5 and/or traffic-related air pollutants may play a role in chronic diseases such as Type 2 diabetes mellitus, t...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sanjay Rajagopalan

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Good lead · 52/100

Likely hiring

Solid budget

Active award

$402,500

FY 2026

Project Title

Targets and targeting of immunometabolism in chronic PM2.5 exposure

Grant Number:

5R01ES033670-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/7/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary PM2.5 is a leading global risk factor for morbidity and mortality and is the leading environmental factor implicated in cardiovascular disease. Recent data suggest that PM2.5 and/or traffic-related air pollutants may play a role in chronic diseases such as Type 2 diabetes mellitus, t...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stella Kang

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 52/100

Likely hiring

Solid budget

Active award

$279,802

FY 2026

Project Title

Tailored Screening for Urinary System Cancers in Patients with Chronic Kidney Disease

Grant Number:

5R01CA262375-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2022

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary Chronic kidney disease (CKD) is a highly prevalent condition, found in 20% of people aged 50 years and older. While it is well known that CKD is strongly associated with cardiovascular mortality, recent work has demonstrated an association with cancer risk that also merits considera...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Accounting><Address><Adherence><Adult><Adult Human><Affect><After Care><After-Treatment><Aftercare><Age><Aged 65 and Over><Anatomic Sites><Anatomic structures><Anatomy><Bladder><Bladder Cancer><Bladder Urinary System><Calibration><Cancer Burden><Cancer Death Rates><Cancers><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Cause of Death><Cessation of life><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Classification><Clinical><Cohort Studies><Colorectal Cancer><Complex><Computer Simulation><Computer based Simulation><Data Set><Death><Detection><Diagnosis><Epidemiology><Evaluation><Event><Frequencies><General Population><General Public><General Radiology><Goals><Grawitz Tumor><Guidelines><Health><Health Status><Heart Vascular><Hypernephroid Carcinoma><Hypernephroma><Hypertension><Incidence><Internal Medicine><K-Awards><K-Series Research Career Programs><Kidney><Kidney Cancer><Kidney Carcinoma><Kidney Mass><Kidney Neoplasms><Kidney Tumor><Kidney Urinary System><Level of Health><Life Expectancy><Link><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Malignant Bladder Neoplasm><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Bladder><Malignant Tumor of the Lung><Malignant Ureter Tumor><Malignant Ureteral Neoplasm><Malignant Ureteral Tumor><Malignant Urinary Tract Neoplasm><Malignant neoplasm of lung><Malignant neoplasm of ureter><Malignant neoplasm of urinary bladder><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Modeling><Monitor><Morbidity><NMR Imaging><NMR Tomography><National Cancer Burden><Natural History><Nephroid Carcinoma><Nephrology><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><Pathway interactions><Patient advocacy><Patients><Perception><Persons><Population><Population Heterogeneity><Practice Guidelines><Preventative strategy><Prevention strategy><Preventive strategy><Primary Care><Proteinuria><Public Health><Publishing><Pulmonary Cancer><Pulmonary malignant Neoplasm><QALY><QOL><Quality of life><Quality-Adjusted Life Expectancy><Quality-Adjusted Life Years><Radiology><Radiology Specialty><Recommendation><Recurrence><Recurrent><Renal Adenocarcinoma><Renal Cancer><Renal Carcinoma><Renal Cell Adenocarcinoma><Renal Cell Cancer><Renal Cell Carcinoma><Renal Mass><Renal Neoplasms><Renal Tumor><Renal function><Renal/Urologic Organ System><Research Career Program><Risk><Risk Factors><Science><Screening for cancer><Severities><Severity of illness><Smoking><Subgroup><Systematics><Testing><Translating><Ureter Cancer><Ureteral Cancer><Urinary Bladder Cancer><Urinary Bladder Malignant Tumor><Urinary Tract Cancer><Urinary system><Urinary tract><Urologic Cancer><Urologic Oncology><Urologic/Renal Body System><Urological Cancer><Urology><Urothelium><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><Zeugmatography><above age 65><adiposity><adulthood><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged><aged 65 and greater><aged 65+><aged ≥65><ages><black female><black male><black man><black men><black women><cancer mortality rate><cancer related death rate><cancer related mortality rate><cancer risk><cancer specific mortality rate><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><chronic kidney disease><circulatory system><clinical practice><co-morbid><co-morbidity><cohort research study><cohort survey><comorbidity><computational simulation><computerized simulation><corpulence><cost><cost effective><cost effectiveness><cost estimate><cost estimation><death risk><disease severity><diverse populations><early cancer detection><epidemiologic><epidemiological><experience><hazard><health level><heterogeneous population><high blood pressure><human old age (65+)><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><kidney adenocarcinoma><kidney function><lung cancer><malignancy><mid life><mid-life><middle age><middle aged><midlife><model-based simulation><models and simulation><mortality><mortality risk><neoplasm/cancer><over 65 years><pathway><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><population diversity><post treatment><recommended screening><renal><screening><screening cancer patients><screening guidelines><screening recommendations><screenings><ultrasound><urinary><urinary bladder><young man><young men><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Matthew Wayne DeCamp

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 50/100

Training-friendly

Solid budget

Recent

Active award

$342,206

FY 2026

Project Title

Health AI and Data Science in Cardiovascular and Pulmonary Disease: Application and Bioethics (HARP-BIO)

Grant Number:

5R25HL146166-08

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/7/2019

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT ABSTRACT This is a renewal application from University of Colorado Anschutz Medical campus that expands the original focus of our existing “PRIDE Academy: Impact of Ancestry and Gender on omics of lung diseases (AGOLD)”. The new descriptive title is “Health AI and Data Science in Cardiovascu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sonia Castro Flores

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 50/100

Training-friendly

Solid budget

Recent

Active award

$342,206

FY 2026

Project Title

Health AI and Data Science in Cardiovascular and Pulmonary Disease: Application and Bioethics (HARP-BIO)

Grant Number:

5R25HL146166-08

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/7/2019

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT ABSTRACT This is a renewal application from University of Colorado Anschutz Medical campus that expands the original focus of our existing “PRIDE Academy: Impact of Ancestry and Gender on omics of lung diseases (AGOLD)”. The new descriptive title is “Health AI and Data Science in Cardiovascu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ivana V Yang

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 50/100

Training-friendly

Solid budget

Recent

Active award

$342,206

FY 2026

Project Title

Health AI and Data Science in Cardiovascular and Pulmonary Disease: Application and Bioethics (HARP-BIO)

Grant Number:

5R25HL146166-08

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/7/2019

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT ABSTRACT This is a renewal application from University of Colorado Anschutz Medical campus that expands the original focus of our existing “PRIDE Academy: Impact of Ancestry and Gender on omics of lung diseases (AGOLD)”. The new descriptive title is “Health AI and Data Science in Cardiovascu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mohamed Boutjdir

SUNY DOWNSTATE MEDICAL CENTER, BROOKLYN, NY

Good lead · 50/100

Training-friendly

Solid budget

Recent

Active award

$340,002

FY 2026

Project Title

Program to Increase Diversity in Cardiovascular Health-Related Research(PRIDE-CVD)

Grant Number:

5R25HL105446-16

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/25/2010

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

This proposal aims to continue support for the Program to Increase Diversity in Cardiovascular Health-Related Research (PRIDE-CVD) formerly known as SIPID (Summer Institute Program to Increase Diversity) at the State University of New York Downstate Health Sciences University (Downstate) in Brooklyn...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Anum Minhas

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$200,879

FY 2026

Project Title

Intersections of pre-pregnancy cardiometabolic risk factors, preeclampsia and cardiovascular disease in a lifecourse framework

Grant Number:

5K23HL171886-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/22/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Anum S. Minhas, MD, MHS, is an Assistant Professor in the Division of Cardiology at the Johns Hopkins University School of Medicine. She seeks a Mentored Patient-Oriented Research Career Development Award in order to obtain essential skills and research experience for an ind...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Prashant Rao

BETH ISRAEL DEACONESS MEDICAL CENTER, BOSTON, MA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$190,338

FY 2026

Project Title

Plasma protein markers of the blood pressure response during exercise and their relation to incident hypertension and cardiovascular disease

Grant Number:

5K23HL177335-02

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT This project addresses the limitations of current cardiovascular disease (CVD) risk assessment methods, which primarily depend on measurements taken at rest. These traditional methods often fail to unveil hidden cardiovascular risks that become apparent only under conditions...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Priya Vassant Borker

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$189,377

FY 2026

Project Title

Understanding the association of sleep on monocyte action in HIV infection

Grant Number:

5K23HL169022-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT As a sleep-medicine physician, I seek to understand how sleep health affects the progression and long-term consequences of chronic disease and, ultimately, implement sleep-based interventions to improve the health of patients. Sleep disorders are highly prevalent among peopl...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lindsey Reif

WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$173,880

FY 2026

Project Title

Preclinical Cardiovascular Disease among Adolescents and Young Adults in Haiti

Grant Number:

5K01HL167654-04

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Dr. Lindsey Reif is a global health epidemiologist with a career goal to leverage epidemiologic research to implement high-impact health interventions for adolescents and young adults living with HIV (AYALH). Over the past decade, she has published 10 first-author papers focused on ...

Research Terms

<18 year old><18 years of age><21+ years old><AIDS Virus><AIDS care><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Active Follow-up><Address><Adolescent><Adolescent HIV><Adolescent Youth><Adolescent and Young Adult><Adult><Adult Human><Age><Age of Onset><Anti-HIV Positivity><Area><Black American><Blood Pressure><Cardiovascular Diseases><Cessation of life><Chronic><Clinic><Collaborations><Complement><Complement Proteins><Data><Death><Development><Development Plans><Disease Outcome><Dyslipidemias><Early Intervention><Ensure><Environment><Epidemic><Epidemiologic Research><Epidemiologist><Epidemiology><Event><Evidence based intervention><Face><Friends><Future><Generations><Goals><HIV><HIV Care><HIV Positive><HIV Positivity><HIV Seroconversion><HIV Seropositivity><HIV antibody positive><HIV disease><HIV disease status><HIV in adolescents><HIV infection in adolescence><HIV infection status><HIV infections in adolescents><HIV load><HIV medical care><HIV patient care><HIV plasma viral load><HIV positive adolescents><HIV related care><HIV related patient care><HIV serostatus><HIV status><HIV viral burden><HIV viral load><HIV+><HIV+ adolescents><HIV-1 care><HIV-1 disease><HIV-1 load><HIV-1 viral burden><HIV-1 viral load><HIV-infected (HIV+) adolescents><HIV-infected adolescents><HIV/AIDS disease><HIV1 infection status><HIV1 status><HTLV-III Seroconversion><HTLV-III Seropositivity><Haiti><Health><High Prevalence><Household><Human Immunodeficiency Viruses><Incidence><Intervention><Investigators><Knowledge><LAV-HTLV-III><Life Cycle><Life Cycle Stages><Life Expectancy><Life Style><Lifestyle><Lymphadenopathy-Associated Virus><Measures><Mental Depression><Mentorship><Methods><Microalbuminuria><Modification><Morbidity><NHLBI><NIH><National Heart, Lung, and Blood Institute><National Institutes of Health><New York><Obesity><Outcome><Paper><Participant><Population><Prevalence><Preventative intervention><Prevention><Primary Prevention><Process><Prospective, cohort study><Provider><Psychosocial Factor><Publishing><Research><Research Methodology><Research Methods><Research Personnel><Researchers><Risk><Risk Factors><Services><Smoking><Stress><Time><Training><Training Support><Unhealthy Diet><United States National Institutes of Health><Virus-HIV><Youth><Youth 10-21><active followup><adiposity><adolescent health><adolescents living with HIV><adolescents with HIV><adult youth><adulthood><age 18><age 18 years><aged><ages><antiretroviral therapy><antiretroviral treatment><assess effectiveness><cardiometabolic><cardiometabolism><cardiovascular disease epidemiology><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder epidemiology><cardiovascular disorder risk><cardiovascular epidemiology><care of HIV-1><career><career development><co-morbid><co-morbidity><cohort><community advisory board><community advisory committee><community advisory panel><comorbidity><complementation><corpulence><depression><design><designing><determine effectiveness><developmental><disability><early onset><effectiveness assessment><effectiveness evaluation><eighteen year old><eighteen years of age><epidemiologic><epidemiologic investigation><epidemiological><evaluate effectiveness><evidence base><examine effectiveness><experience><faces><facial><follow up><follow-up><followed up><followup><global health><high risk><high-risk adolescents><human immunodeficiency virus care><human immunodeficiency virus disease><implementation framework><implementation research framework><implementation science><implementation science framework><improved><intervention for prevention><investigate epidemiology><juvenile><juvenile human><life course><life-style factor><lifestyle factors><low income country><member><mortality><multidisciplinary><perinatal HIV><poor diet><population based><practical implementation><pragmatic implementation><pre-clinical><preclinical><prehypertension><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><psychosocial><psychosocial variables><research and methods><screening><screenings><skills><social stigma><stigma><study epidemiology><survey epidemiology><therapy duration><young adult><young adult age><young adulthood><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Patricia Marie West

HENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, EAST LANSING, MI

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$169,189

FY 2026

Project Title

Advancing Cardiovascular Health Among Adolescents with Intellectual Disabilities: Co-Development of Technology Interventions to Enhance Physical Activity

Grant Number:

1K01NR022135-01

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/25/2026

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Adolescents with intellectual disabilities (ID) face significant health issues, particularly in managing chronic conditions such as cardiovascular (CV) health risks. These issues are exacerbated by limited physical activity (PA), health literacy challenges, and a lack of evidence-based health interv...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Arvind Kant Pandey

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$167,400

FY 2026

Project Title

Immuno-Metabolic Regulation of Vascular Dysfunction by CD70

Grant Number:

5K08HL177156-02

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2025

End Date:

2/28/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Cardiovascular diseases constitute a tremendous health care burden, and despite increased attention, cardiovascular mortality continues to increase in the United States and worldwide. While immune activation and inflammation are critical to atherosclerotic cardiovascular di...

Research Terms

<(TNF)-α><ASCVD><Affect><Applications Grants><Assay><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Attention><Award><Binding><Bioassay><Bioavailability><Bioenergetics><Biological Assay><Biological Availability><Biological Response Modifiers><Biology><Biomodulators><Biosensor><Blood Vessels><Cachectin><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cause of Death><Cell Communication and Signaling><Cell Function><Cell Membrane Lipid Rafts><Cell Physiology><Cell Process><Cell Signaling><Cellular Function><Cellular Metabolic Process><Cellular Physiology><Cellular Process><Cessation of life><Characteristics><Clinical Investigator Award><Closure by Ligation><Co-Immunoprecipitations><Data><Death><Dedications><Development><Development Plans><ENOS><Endogenous Nitrate Vasodilator><Endothelial Cells><Endothelial Nitric Oxide Synthase><Endothelium><Endothelium-Derived Nitric Oxide><Environment><Enzyme Gene><Enzymes><Foundations><Funding><Generalized Growth><Generations><Genetic Polymorphism><Goals><Grant Proposals><Growth><Health Care><Heart Vascular><Hospitals><Immune><Immune Cell Activation><Immune Mediators><Immune Mediators/Modulators><Immune Targeting><Immunes><Impairment><Inflammation><Inflammation Mediators><Inflammatory><Injury><Institution><Intermediary Metabolism><Intracellular Communication and Signaling><Investigators><K-Awards><K-Series Research Career Programs><K08 Mechanism><K08 Program><KO mice><Knock-out Mice><Knockout Mice><Label><Laboratories><Leukocyte Rolling><Ligation><Link><Macromolecular Complexes><Macrophage-Derived TNF><Mediating><Membrane Microdomains><Membrane Potentials><Mentored Clinical Scientist Development Award (K08)><Mentored Clinical Scientists Development Award><Mentors><Metabolic><Metabolic Pathway><Metabolic Processes><Metabolism><Mice><Mice Mammals><Mitochondria><Molecular Interaction><Monocyte-Derived TNF><Mononitrogen Monoxide><Morphology><Murine><Mus><Myography><NOS3><NOS3 gene><Nitric Oxide><Nitric Oxide Synthase 3><Nitrogen Monoxide><Nitrogen Protoxide><Null Mouse><Oxidation-Reduction><Oxidative Stress><Pathogenesis><Pathway interactions><Peptide/Protein Chemistry><Phased Career Development><Phenotype><Physicians><Physiologic><Physiologic Availability><Physiological><Physiology><Principal Investigator><Protein Chemistry><Proteins><Redox><Regulation><Research><Research Activity><Research Career Program><Research Personnel><Research Resources><Research Support><Researchers><Resources><Resting Potentials><Role><Scientist><Signal Transduction><Signal Transduction Systems><Signaling><Sphingolipid Microdomains><Sphingolipid-Cholesterol Rafts><Subcellular Process><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Techniques><Testing><Time><Tissue Growth><Training><Training Activity><Training Programs><Transmembrane Potentials><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Type III nitric oxide synthase><United States><Vascular Diseases><Vascular Disorder><Vasodilatation><Vasodilation><Vasorelaxation><Viral><Woman><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><biological sensor><biological signal transduction><blood vessel disorder><cardiovascular disorder><career development><cell metabolism><cellular metabaolism><circulatory system><developmental><disease phenotype><endothelial cell derived relaxing factor><endothelial dysfunction><extracellular><health care burden><immune activation><inflammatory mediator><injuries><insight><knock-down><knockdown><leukocyte activation><lipid raft><medical college><medical schools><member><metabolic profile><metabolism measurement><metabolomics><metabonomics><migration><mitochondrial><mitochondrial membrane><mortality><mouse model><murine model><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><ontogeny><overexpress><overexpression><oxidation reduction reaction><pathway><phenome><polymorphism><programs><protein protein interaction><response><responsible research conduct><scRNA sequencing><scRNA-seq><school of medicine><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><skills><social role><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic target><training module><vascular><vascular dysfunction><vascular inflammation><vasculopathy>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Carl G Streed

BOSTON MEDICAL CENTER, BOSTON, MA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$166,277

FY 2026

Project Title

Building methods to assess and address cardiovascular health in transgender adults

Grant Number:

5K01HL151902-05

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/15/2021

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary: Guided by current prediction models utilized to address and prevent atherosclerotic cardiovascular disease (CVD), the proposed project investigates how gender identity and hormone therapy are related to cardiovascular health in transgender adults. The projects three specific aims ar...

Research Terms

<21+ years old><ASCVD><Accounting><Active Follow-up><Address><Adult><Adult Human><Affect><Algorithms><Apoplexy><Area><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Attitude><Birth><Boston><Brain Vascular Accident><Cardiac infarction><Cardiology><Cardiovascular Diseases><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Classification><Clinical Skills><Code><Coding System><Cognitive Discrimination><Collaborations><Consolidated Framework for Implementation Research><Consolidated Framework for Implementation Science><Consolidated Framework for Implementing Change><Data><Data Analyses><Data Analysis><Data Collection><Death><Development><Diabetes Mellitus><Diagnosis><Discrimination><Disease Outcome><Electronic Health Record><Endocrine Gland Secretion><Endocrine Therapy><Endocrinology><Equation><Exogenous Hormone Therapy><Exogenous Hormone Use><Faculty Seminar><Faculty Workshop><Federally Qualified Health Center><Female><Future><Gender><Gender Identity><Gender and Sexual Minorities><Goals><Grant><Health><Hormonal Therapy><Hormone use><Hormones><Hyperlipemia><Hyperlipidemia><Hypertension><Individual><Intervention><Intramuscular><Investigators><K-Awards><K-Series Research Career Programs><K01 Award><K01 Mechanism><K01 Program><Knowledge><Mentored Research Scientist Development Award><Mentored Training Award><Mentors><Mentorship><Metabolism and Endocrinology><Methods><Modeling><Morbidity><Myocardial Infarct><Myocardial Infarction><NHLBI><NIH><National Heart, Lung, and Blood Institute><National Institutes of Health><Oral><Outcome><Parturition><Patients><Persons><Play><Population><Preventative care><Preventive care><Primary Prevention><Probabilistic Models><Probability Models><Procedures><Qualitative Research><Recommendation><Records><Research><Research Career Program><Research Personnel><Research Resources><Research Scientist Development Award><Researchers><Resources><Review Literature><Risk><Risk Assessment><Risk Factors><Risk Management><Role><Route><Scientist><Sensitivity and Specificity><Services><Sexual and Gender Minorities><Site><Statistical Models><Stroke><Survey Instrument><Surveys><Systematics><Teacher Workshop><Therapeutic Hormone><Tobacco><Tobacco Consumption><Tobacco use><Training><United States National Institutes of Health><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Writing><active followup><adulthood><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><brain attack><cardiac infarct><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cerebral vascular accident><cerebrovascular accident><cis-female><cis-gender><cis-gender man><cis-gender woman><cis-male><cis-man><cis-woman><cisgender><cisgender man><cisgender men><cisgender woman><clinical decision-making><co-morbid><co-morbidity><cohort><community engagement><comorbidity><computer based prediction><conference><convention><coronary attack><coronary infarct><coronary infarction><data interpretation><data warehouse><developmental><diabetes><disease model><disorder model><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><engagement with communities><experience><faculty conference><faculty panel><follow up><follow-up><followed up><followup><gender affirmative care><gender affirming care><gender affirming healthcare><gender affirming service><gender assigned><gender minority><heart attack><heart infarct><heart infarction><high blood pressure><hormone therapy><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation science><improved><indexing><male><meeting><meetings><mortality><multidisciplinary><novel><predictive modeling><prevent><preventing><programs><recruit><risk mitigation><risk prediction algorithm><risk prediction model><sex><sex assigned><skills><social role><statistical linear mixed models><statistical linear models><statistics><stroked><strokes><success><summit><symposia><symposium><tobacco product use><trans*><trans-men><trans-women><transgender><transgender man><transgender men><transgender women><transman><transmen><transwoman><transwomen><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Justin McNair Canada

VIRGINIA COMMONWEALTH UNIVERSITY, RICHMOND, VA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$149,048

FY 2026

Project Title

The Relationship of Exercise Associated Cardiac Reserve on Peak Oxygen Consumption and Frailty Measures in Individuals Undergoing Allogeneic Hematopoietic Stem Cell Transplant.

Grant Number:

5K23HL159270-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This K23 project will prepare the Principal Investigator, Justin M. Canada, PhD, to develop as an independent clinical/translational researcher who is expert in a novel form of cardiopulmonary exercise stress measurement – cardiovascular magnetic resonance imaging (MRI) – to identif...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Debra I Diz

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Good lead · 48/100

Training-friendly

Very recent

Active award

$132,840

FY 2026

Project Title

Excellence in Cardiovascular Sciences Summer Research-Renewal

Grant Number:

5R25HL092618-19

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/15/2008

End Date:

1/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The primary goal of the Excellence in Cardiovascular Sciences (EICS) Program (R25 HL92618 renewal) is to provide exposure to outstanding summer research experiences for undergraduate (UG) students focusing on mechanisms of cardiovascular (CV) diseases and CV-related health disparities, with an empha...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David R. Soto Pantoja

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Good lead · 48/100

Training-friendly

Very recent

Active award

$132,840

FY 2026

Project Title

Excellence in Cardiovascular Sciences Summer Research-Renewal

Grant Number:

5R25HL092618-19

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/15/2008

End Date:

1/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The primary goal of the Excellence in Cardiovascular Sciences (EICS) Program (R25 HL92618 renewal) is to provide exposure to outstanding summer research experiences for undergraduate (UG) students focusing on mechanisms of cardiovascular (CV) diseases and CV-related health disparities, with an empha...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Daniel J Fehrenbach

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$123,930

FY 2026

Project Title

Novel role of ROCK2 in Immune Mechanisms of Takotsubo Cardiomyopathy

Grant Number:

5K99HL177309-02

Activity Code:

K99

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/20/2024

End Date:

11/30/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Takotsubo Cardiomyopathy (TCM) is an acute, life-threatening condition triggered by an intense physical or emotional stressor and characterized by cardiac dysfunction, apical ballooning of the left ventricle, and thinning of the ventricular wall. With maximal medical care, patients may recover, but ...

Research Terms

<ATP-protein phosphotransferase><Acute><Adoptive Transfer><AngII><Angiotensin II><Apical><Assay><Attenuated><Automobile Driving><Bioassay><Bioavailability><Biological Assay><Biological Availability><Blood Pressure><Blood monocyte><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><Cardiac><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Catecholamines><Cell Culture Techniques><Cessation of life><Chronic><Clinic><Data><Death><Development><Development Plans><Diagnosis><Dose><Drops><Dysfunction><EFRAC><Ejection Fraction><Emotional><Environment><Enzyme Gene><Enzymes><Event><Exhibits><FDA approved><Fibrosis in the heart><Fibrosis in the myocardium><Fibrosis within the heart><Fibrosis within the myocardium><Fibrotic myocardium><Foundations><Functional disorder><Future><General Population><General Public><Genetic Technics><Genetic Techniques><Guidelines><Heart><Heart Vascular><Heart failure><History><Human><Hypertension><Immune><Immune Cell Activation><Immune response><Immunes><Immunity><In Vitro><Infiltration><Inflammation><Inflammatory><Infusion><Infusion procedures><Investigators><Isoprenaline><Isopropyl Noradrenaline><Isopropylarterenol><Isopropylnoradrenaline><Isopropylnorepinephrine><Isoproterenol><Isuprel><Kinase Family Gene><Kinases><Knock-out><Knockout><Laboratories><Lead><Leanness><Learning><Left Ventricles><Left ventricular structure><Life><Life Expectancy><Long-Term Care><Long-Term Potentiation><Macrophage><Macrophage Activation><Marrow monocyte><Medical><Mentors><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Murine><Mus><Myelogenous><Myeloid><Myeloid Cells><Myocardial Diseases><Myocardial Disorder><Myocardial depression><Myocardial dysfunction><Myocardiopathies><Mφ><Oral><Overdose><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patients><Pb element><Persons><Phagocytes><Phagocytic Cell><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phase><Phenotype><Phosphotransferase Gene><Phosphotransferases><Physiologic><Physiologic Availability><Physiological><Physiopathology><Play><Pre-Clinical Model><Preclinical Models><Prevalence><Production><Protein Kinase><RNA Seq><RNA sequencing><RNAseq><Recommendation><Recording of previous events><Recovery><Research><Research Personnel><Researchers><Risk><Rodent Model><Role><Stress><Stress cardiomyopathy><Sympathins><Symptoms><Syndrome><Takotsubo><Testing><Thinness><Tissues><Training><Translating><Transphosphorylases><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Ventricular><Work><acute coronary syndrome><amebocyte><attenuate><attenuates><biological adaptation to stress><cardiac dysfunction><cardiac failure><cardiac fibrosis><cardiac function><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><care for patients><care of patients><career><career development><caring for patients><cell culture><cell cultures><circulatory system><coronary fibrosis><cytokine><death risk><developmental><driving><experience><extended care><fibrotic heart><function of the heart><glycogen synthase a kinase><heart dysfunction><heart fibrosis><heart function><heavy metal Pb><heavy metal lead><high blood pressure><histories><host response><hydroxyalkyl protein kinase><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><hypoimmunity><immune activation><immune deficiency><immune system response><immunodeficiency><immunoresponse><in vivo><infusions><inhibitor><malleable risk><modifiable risk><monocyte><mortality risk><myocardial fibrosis><myocardium disease><myocardium disorder><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutics><new therapy><new therapy approaches><new treatment approach><new treatment strategy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutics><novel therapy><novel therapy approach><pathophysiology><pathway><pharmaceutical><phosphorylase b kinase kinase><pre-clinical><preclinical><prevent><preventing><progenitor><programs><reactioncrisis><recruit><response><rho><social role><stress response><stress-induced cardiomyopathy><stressreaction><stressor><therapeutic target><transcriptome sequencing><transcriptomic sequencing><transcriptomics>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Denis Routkevitch

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 48/100

Training-friendly

Very recent

Active award

$54,538

FY 2026

Project Title

Spinal Cord Injury: A Cardiovascular Perspective using Ultrasound

Grant Number:

5F30HL168823-03

Activity Code:

F30

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The guidelines for the cardiovascular care of spinal cord injury (SCI) have remained essentially unchanged since mean arterial pressure (MAP) management at 85-90 mmHg was recommended 20 years ago. Due to the heterogeneity in SCI, there is a critical need for a precision medicine trea...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Keira Hassel

UNIVERSITY OF CINCINNATI, CINCINNATI, OH

Good lead · 48/100

Training-friendly

Very recent

Active award

$54,538

FY 2026

Project Title

Determining the regulatory role of microprotein ALN on SERCA2a and heart contractility

Grant Number:

7F30HL172585-02

Activity Code:

F30

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

8/15/2025

End Date:

1/2/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Cardiovascular disease is the leading cause of morbidity and mortality worldwide. Cardiomyocyte calcium (Ca2+) dysregulation is a central feature of disease and is largely driven by defects in the activity of a critical Ca2+ pump called the sarco/endoplasmic reticulum Ca2+ A...

Research Terms

<21+ years old><ATP phosphohydrolase (Ca(2+)-transporting)><Active Biologic Transport><Active Biological Transport><Active Transport><Adenosine Cyclic Monophosphate-Dependent Protein Kinases><Adrenergic Agents><Adrenergic Drugs><Adrenergics><Adult><Adult Human><Affect><Affinity><Agonist><Alanine><AngII><Angiotensin II><Area><Autoregulation><Binding><Body System><Body Tissues><Ca(2+)-Transporting ATPase><Ca2+ ATPase><Ca2+ transporting ATPase><Calcium><Calcium ATPase><Calcium Adenosine Triphosphatase><Calcium Ion Signaling><Calcium Pump><Calcium Signaling><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Muscle Cells><Cardiac Myocytes><Cardiocyte><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Children's Hospital><Chronic><Co-Immunoprecipitations><Common Rat Strains><Coupled><Cyclic AMP-Dependent Protein Kinases><Cytosol><Data><Defect><Development><Disease><Disease Progression><Disorder><Dissociation><Dysfunction><EDN1><ET-1><Endoplasmic Reticulum><Endothelin><Endothelin Type 1><Endothelin-1><Endothelium-Derived Vasoconstrictor Factors><Ergastoplasm><Event><Functional disorder><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G alpha q Protein><G(s), alpha Subunit><G(s), α Subunit><G(s)alpha><G(s)α><G-Protein-Coupled Receptors><GPCR><GTP-Binding Protein alpha Subunits, Gs><GTP-Binding Protein α Subunits, Gs><Galphaq Protein><Goals><Gq G-Protein><Gq Protein><Gq alpha Family G-Protein><Gs alpha Family G-Protein><Gsα><Gαq Protein><Gαs><Health><Heart><Heart Contractilities><Heart Diseases><Heart Muscle Cells><Heart Vascular><Heart myocyte><Homeostasis><In Vitro><Intracellular Communication and Signaling><Isoprenaline><Isopropyl Noradrenaline><Isopropylarterenol><Isopropylnoradrenaline><Isopropylnorepinephrine><Isoproterenol><Isuprel><KO mice><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Knowledge><L-Serine><Laboratories><Measures><Mediating><Medical center><Mice><Mice Mammals><Molecular Interaction><Morbidity><Murine><Mus><Muscle Cells><Mutate><Myocytes><Neonatal><Neuroendocrine><Neuroendocrine System><Neurosecretory Systems><Null Mouse><Organ System><PKA><Pathway interactions><Pediatric Hospitals><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D. student><PhD student><PhD. student><Phenylephrine><Phosphorylation><Physiological Homeostasis><Physiology><Physiopathology><Position><Positioning Attribute><Prevention><Protein Kinase A><Protein Phosphorylation><Proteins><Rat><Rats Mammals><Rattus><Receptor Protein><Receptor Signaling><Regulation><Regulatory Ns Protein><Relaxation><Research><Role><Sarcoplasmic Reticulum><Sequence Homology><Serine><Signal Induction><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Stimulatory Gs G-Protein><Stimulus><Testing><Tissues><Uphill Transport><Ventricular><Work><adulthood><alpha Subunit Stimulatory GTP-Binding Protein><alpha-Gs><base><bases><biological signal transduction><cAMP-Dependent Protein Kinases><calcium transporting ATPase><cardiomyocyte><cardiovascular disorder><cell type><circulatory system><developmental><doctoral student><experience><experiment><experimental research><experimental study><experiments><gain of function><gene delivery system><heart disorder><in vivo><insight><loss of function><mimetics><mortality><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathophysiology><pathway><phospholamban><prevent><preventing><receptor><response><social role><therapeutic target><α-Gs>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nathalie Dieujuste

UNIVERSITY OF DENVER (COLORADO SEMINARY), DENVER, CO

Good lead · 48/100

Training-friendly

Very recent

Active award

$52,538

FY 2026

Project Title

Association of Stressful Life Experiences Reported During Pregnancy with Cardiovascular Disease Risk in Mothers.

Grant Number:

5F31HL178223-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

1/6/2025

End Date:

1/5/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Cardiovascular disease (CVD) is the leading cause of death for women in the US. Pregnancy is a key sensitive period for CVD risk during which rapid maternal cardiovascular changes occur. There is evidence that adverse pregnancy outcomes (e.g., hypertensive disorders of pregnancy) significantly predi...

Research Terms

<21+ years old><Address><Adult><Adult Human><American Heart Association><BMI><BMI percentile><BMI z-score><Behavioral><Biological><Blood Pressure><Blood Volume><Body fat><Body mass index><Buffers><Cardiac><Cardiac Output><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Childbirth><Childhood><Decrease disparity><Enrollment><Fellowship><Funding><Future><General Population><General Public><Gestation><Goals><Grant><Heart Vascular><Hypertension><Hypertension-Associated Pregnancy Disorder><Individual><Intervention><Investigators><Knowledge><Life><Life Experience><Link><Longitudinal Studies><Longitudinal Surveys><Lower disparity><Maternal Health><Mentorship><Methodology><Mothers><NIH><National Institutes of Health><Onset of illness><Pathway interactions><Perinatal><Peripartum><Physiology><Population><Postpartum Period><Predisposition><Pregnancy><Prevention><Productivity><Psychosocial Assessment and Care><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk Factors><Role><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Stress><Stressful Event><Susceptibility><Testing><Training><United States National Institutes of Health><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vulnerable Populations><Woman><Women's mortality><Writing><adulthood><adverse childhood events><adverse childhood experiences><adverse pregnancy outcome><after pregnancy><analyzing longitudinal><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><biologic><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><career><child birth><circulatory system><cohort><death among females><death among women><death in females><death in women><disease onset><disorder onset><disparity reduction><enroll><experience><female death><female mortality><graduate student><heart output><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disease during pregnancy><hypertensive disease in pregnancy><hypertensive disease of pregnancy><hypertensive disorder><hypertensive disorder during pregnancy><hypertensive disorder in pregnancy><hypertensive disorder of pregnancy><indexing><long-term study><longitudinal analysis><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal research study><longitudinal study design><maternal stress><mitigate disparity><mortality among females><mortality among women><mortality in females><mortality in women><pathway><pediatric><perinatal period><perinatal phase><post pregnancy><post-partum><pregnancy induced hypertensive disorder><pregnancy related hypertensive disease><pregnancy-specific hypertensive disorder><prenatal><prepregnancy><prevent><preventing><prospective><psychosocial><psychosocial assessment><psychosocial care><psychosocial stresses><psychosocial stressors><psychosocial studies><psychosocial support><reduce disparity><reduction in disparity><resilience factor><resiliency factor><risk prediction algorithm><risk prediction model><skills><social role><statistical analysis><stressed mothers><stressful experience><stressful life event><stressful life experience><stressor><unborn><vulnerable group><vulnerable individual><vulnerable people><waist circumference><women's death>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Grace Tietz

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 48/100

Training-friendly

Very recent

Active award

$50,114

FY 2026

Project Title

An Ancestry-Informed Approach to Improve Genetic Testing for Cardiovascular Disease

Grant Number:

5F31HL176183-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

2/1/2025

End Date:

1/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Cardiovascular disease (CVD) is the leading cause of death in the United States, making it a promising disease for genetic testing to predict those at risk and prevent problems before they start. Indeed, genetic testing for CVD is now being implemented in clinic, but we are ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARK T GROUDINE

FRED HUTCHINSON CANCER CENTER, SEATTLE, WA

Good lead · 46/100

Large award

Recent

Active award

$10,225,386

FY 2026

Project Title

WOMEN'S HEALTH INITIATIVE (WHI) CLINICAL COORDINATING CENTER - TASK AREA A AND A2

Grant Number:

75N92021D00001-0-759202600001-1

Activity Code:

N01

Mechanism:

R and D Contracts

Agency:

NIH

Start Date:

2/1/2026

End Date:

1/31/2027

Why this may be worth a closer look

• Large budget suggests more room for personnel or project growth.

Project Abstract

The overall goal of the Women?s Health Initiative (WHI) Renewal is to continue to serve as a resource for innovative epidemiological research and to expand knowledge about the determinants of cardiovascular disease among older women, successful aging in the absence of cardiovascular disease, and mai...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ben Steven Gerber

UNIV OF MASSACHUSETTS MED SCH WORCESTER, WORCESTER, MA

Exploratory lead · 44/100

Training-friendly

Solid budget

Active award

$304,077

FY 2026

Project Title

CardiOvascular Digital hEalth Research (CODER) Training Program

Grant Number:

5T32HL171799-03

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT ABSTRACT The goal of CardiOvascular Digital hEalth Research (CODER) is to develop postdoctoral investigators with expertise in cardiovascular (CV) digital health by bringing together highly skilled and collaborative training faculty from multiple disciplines, with the ultimate goal of develo...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David D. McManus

UNIV OF MASSACHUSETTS MED SCH WORCESTER, WORCESTER, MA

Exploratory lead · 44/100

Training-friendly

Solid budget

Active award

$304,077

FY 2026

Project Title

CardiOvascular Digital hEalth Research (CODER) Training Program

Grant Number:

5T32HL171799-03

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT ABSTRACT The goal of CardiOvascular Digital hEalth Research (CODER) is to develop postdoctoral investigators with expertise in cardiovascular (CV) digital health by bringing together highly skilled and collaborative training faculty from multiple disciplines, with the ultimate goal of develo...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yanfang Su

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$166,425

FY 2026

Project Title

Population strategies to reduce sodium intake and cardiovascular diseases in the United States: Applying RE-AIM to policy implementation

Grant Number:

5K01HL166688-03

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/14/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Cardiovascular disease (CVD) deaths in the United States approached 1 million in 2019, accounting for 33% of annual mortality. Americans consume 3,400 mg of sodium per day, nearly 50% higher than the limit recommended by the U.S. FDA and WHO. Population sodium reduction is a strategy to reduce CVD d...

Research Terms

<0-11 years old><21+ years old><Acceleration><Accounting><Address><Adopted><Adoption><Adult><Adult Human><Age><American><Area><Award><Awareness><Black><Black race><CVD prevention><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Categories><Cessation of life><Child><Child Youth><Children (0-21)><Consumption><Country><County><Data><Data Analyses><Data Analysis><Data Sources><Death><Dedications><Dimensions><Economic Income><Economical Income><Equity><Excess Dietary Salt><Excess Salt><Feasibility Studies><Food and Drug Administration><Formulation><Foundations><Funding><Future><Goals><Health><Heart Vascular><High dietary salt><Hospitals><Household><Income><Increased dietary salt><Institution><Intake><Interview><Job Location><Job Place><Job Setting><Job Site><Label><Language><Learning><Low income><Maintenance><Math Models><Measures><Mentors><Mentorship><Methods><Modeling><NHLBI><Na element><National Heart, Lung, and Blood Institute><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Nursing Homes><Outcome Study><Persons><Policies><Policy Maker><Population><Public Health><RE-AIM><Race><Races><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Recommendation><Research><Role><Schools><Science><Scientist><Sodium><System><Target Populations><Training><Translations><USFDA><United States><United States Food and Drug Administration><Universities><Visualization><Washington><Work Location><Work Place><Work-Site><Workplace><Worksite><World Health Organization><adulthood><ages><burden of disease><burden of illness><cardiac disease prevention><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><circulatory system><cohort><comparing females and males><comparing women and men><cost><data interpretation><dietary><disease burden><disease model><disorder model><disparity in health><elevated dietary salt><females compared to males><females compared with males><females versus males><females vs. males><food preparation><health disparity><health equity><implementation science><improved><incomes><innovate><innovation><innovative><interactive tool><kids><mathematic model><mathematical model><mathematical modeling><milligram><mortality><multidisciplinary><novel><nursing home><overconsume dietary salt><post-doctoral training><public education><racial><racial background><racial origin><reach, efficacy, adoption, implementation, and maintenance><sex><simulation><social role><tool><translation><women compared to men><women compared with men><women versus men><women vs. men><work setting><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jamie Faro

UNIV OF MASSACHUSETTS MED SCH WORCESTER, WORCESTER, MA

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$162,485

FY 2026

Project Title

ActivityChoice: A clinic-delivered implementation program to increase physical activity and decrease cardiovascular disease risk amongst cancer survivors

Grant Number:

5K01HL163254-04

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/13/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Cancer survivors have 1.7-18.5-fold increased risk, and 1.3-3.6-fold increased mortality of cardiovascular disease (CVD). Physical activity has been shown to ameliorate risk, but survivors’ levels are far below the general population. Due to this, provider physical activity recommend...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Aleda Leis

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$127,710

FY 2026

Project Title

Cytomegalovirus, midlife inflammation, and subclinical cardiovascular disease: the Study of Women's Health Across the Nation

Grant Number:

1K01AG092928-01A1

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2026

End Date:

11/30/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Cytomegalovirus (CMV) is a common beta herpesvirus with over half of adults in the US infected by age 40 and higher seroprevalence among women than men. Though most acute CMV infection in immunocompetent individuals is mild or asymptomatic, following acute infection the virus remains in a latent sta...

Research Terms

<21+ years old><7S Gamma Globulin><Acute><Address><Adipose tissue><Adult><Adult Human><Adult females><Adult women><Adult-Onset Diabetes Mellitus><Age><Aging><Antibodies><Award><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Biological Aging><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Biology of Aging><Blood Pressure><Blood Serum><Body Composition><Body System><CMV><CMV infection><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Causality><Cause of Death><Chronic><Chronic Disease><Chronic Illness><Clinical><Communicable Diseases><Complex><Cross Sectional Analysis><Cytomegalic Inclusion Disease><Cytomegalovirus><Cytomegalovirus Infections><Data><Data Collection><Decision Making><Development><Diabetes Mellitus><Disease><Disease Outcome><Disorder><Epidemiology><Ethnic Origin><Ethnicity><Etiology><Fatty Tissue><Female Groups><Female Health><Females in adulthood><Future><Generalized Growth><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Goals><Grant><Growth><HCMV><HPGF><Heart Vascular><Hepatocyte-Stimulating Factor><Herpesviridae><Herpesviruses><Heterogeneity><Hormonal Change><Hybridoma Growth Factor><Hypertension><IFN-beta 2><IFNB2><IL-6><IL6 Protein><IgG><Immune><Immune response><Immunes><Immunocompetent><Immunoglobulin G><Immunology><Inclusion Disease><Individual><Infection><Infectious Diseases><Infectious Disorder><Inflammation><Inflammatory><Injury><Interdisciplinary Research><Interdisciplinary Study><Interleukin-6><Intervention><Ketosis-Resistant Diabetes Mellitus><Latent virus infection phase><Life Cycle><Life Cycle Stages><MGI-2><Maturity-Onset Diabetes Mellitus><Measurement><Measures><Mediating><Menses><Menstruation><Metabolic Diseases><Metabolic Disorder><Methods><Michigan><Midlife women><Modification><Morbid Obesity><Multidisciplinary Collaboration><Multidisciplinary Research><Myeloid Differentiation-Inducing Protein><NIDDM><NIH><National Institute of Aging><National Institute on Aging><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Organ System><Outcome><Pathway interactions><Pattern><Perimenopausal><Perimenopause><Physiologic><Physiological><Plasmacytoma Growth Factor><Position><Positioning Attribute><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Pre-Menopause><Pre-menopausal Period><Premenopausal><Premenopausal Period><Premenopause><Prevalence><Preventative care><Preventative strategy><Prevention><Prevention strategy><Preventive care><Preventive strategy><Process><Public Health Schools><Race><Races><Reporting><Research><Risk><Risk Factors><Salivary Gland Virus Disease><Salivary Gland Viruses><Seroprevalences><Serum><Severe obesity><Site><Slow-Onset Diabetes Mellitus><Socio-economic status><Socioeconomic Status><Stable Diabetes Mellitus><Stimulus><Study of Women's Health Across the Nation><T2 DM><T2D><T2DM><Testing><Thesaurismosis><Tissue Growth><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Viral><Viral Diseases><Virus Diseases><Visceral><Visit><Woman><Women in adulthood><Women's Group><Women's Health><Women's mortality><Women's study><Work><accelerated aging><accelerated biological age><accelerated biological aging><acute infection><adipose><adiposity><adult onset diabetes><adulthood><after menopause><age acceleration><ages><aging associated><aging related><bio-markers><biobank><biologic marker><biological process of age><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood lipid><cardiovascular disease epidemiology><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder epidemiology><cardiovascular disorder risk><cardiovascular epidemiology><cardiovascular risk><cardiovascular risk factor><career><carotid intima-media thickness><causation><chronic disorder><circulatory system><cohort><corpulence><critical period><cytokine><cytomegalovirus group><death among females><death among women><death in females><death in women><developmental><diabetes><disease causation><disease prognosis><disease prognostication><epidemiologic><epidemiological><extreme obesity><female at midlife><female death><female mortality><female study><following menopause><geographic site><healing><healthy aging><healthy human aging><herpes virus><high blood pressure><high risk><host response><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><immune competent><immune system response><immunoresponse><improved><individualized prevention><injuries><insight><interferon beta 2><ketosis resistant diabetes><latent viral infection><latent virus infection><life course><maturity onset diabetes><meeting><meetings><men><menopause transition><menstrual period><metabolism disorder><mid life><mid-life><mid-life female><middle age><middle aged><middle-aged female><middle-aged women><midlife><monthly period><monthly periods><mortality><mortality among females><mortality among women><mortality in females><mortality in women><novel><older adult><older adulthood><ontogeny><past menopause><pathway><peri-menopausal><peri-menopause><personalized prevention><post-menopausal><postmenopausal><postmenopausal status><pre-menopausal><precision medicine><precision prevention><precision-based medicine><premenopausal status><prospective><racial><racial background><racial origin><repair><repaired><seropositive><sex><skills><socio-economic position><socioeconomic position><specimen bank><specimen repository><study among females><study among women><study in females><study in women><study on females><study on women><study within women><transition to menopause><transitional menopause><type 2 DM><type II DM><type two diabetes><viral infection><virus infection><virus-induced disease><white adipose tissue><women at midlife><women in midlife><women's death><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kelly Brooke Jarvis

NORTHWESTERN UNIVERSITY AT CHICAGO, CHICAGO, IL

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$124,065

FY 2026

Project Title

Heart-brain MRI for the evaluation of hemodynamic coupling in aging and Alzheimer's disease

Grant Number:

5K01AG080070-04

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary/Abstract Cardiovascular risk factors have been implicated in Alzheimer's disease and related dementias, however, mechanisms underlying heart-brain hemodynamic coupling are not well understood. Aortic stiffening has been associated with increased dementia risk. In addition to brain ch...

Research Terms

<(4D) flow MRI><21+ years old><3-D><3-Dimensional><3D><4-D MR imaging><4-D MRI><4-D flow MR imaging><4-D flow MRI><4-D flow imaging><4-D flow magnetic resonance imaging><4-D magnetic resonance imaging><4D MR imaging><4D MRI><4D flow MR imaging><4D flow MRI><4D flow imaging><4D flow magnetic resonance imaging><4D magnetic resonance imaging><AD and related dementia><AD dementia><AD patients><AD related dementia><ADRD><Abeta clearance><Acceleration><Adult><Adult Human><Affect><Age><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's patient><Alzheimers Dementia><Amentia><Amyloid β clearance><Aorta><Aβ clearance><Blood><Blood Flow Velocity><Blood Pressure><Blood Reticuloendothelial System><Blood Vessels><Blood flow><Brain><Brain Nervous System><Brain Vascular><Brain Vascular Disorders><Brain hemodynamics><Brain imaging><Buffers><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Care Givers><Caregivers><Cerebrovascular Disease><Cerebrovascular Disorders><Cerebrum><Chest><Clinical><Cognitive aging><Complex><Coupling><Data><Dedications><Dementia><Development><Encephalon><Evaluation><Foundations><Future><General Radiology><Goals><Head and Neck><Head and neck structure><Heart><Heart Vascular><Hypertension><Imaging Procedures><Imaging Technics><Imaging Techniques><Impairment><Individual><Intracranial Vascular Diseases><Intracranial Vascular Disorders><Lead><Link><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maps><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methodology><Methods><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Nuclear Magnetic Resonance Imaging><Pathology><Pattern><Pb element><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D. student><PhD student><PhD. student><Physiologic><Physiologic pulse><Physiological><Pilot Projects><Postdoc><Postdoctoral Fellow><Primary Senile Degenerative Dementia><Production><Protocol><Protocols documentation><Pulsatile Flow><Pulsatile Perfusion><Pulsating Flow><Pulse><QOL improvement><Radiology><Radiology Specialty><Research><Research Associate><Scanning><Structure><Techniques><Thorace><Thoracic><Thorax><Training><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><White Matter Hyperintensity><Zeugmatography><a-beta peptide clearance><abeta peptide clearance><adulthood><age associated alterations><age associated changes><age correlated alterations><age correlated changes><age dependent alterations><age dependent changes><age induced alterations><age induced changes><age related alterations><age related changes><age specific alterations><age specific changes><ages><aging associated alterations><aging associated changes><aging correlated alterations><aging correlated changes><aging dependent alterations><aging dependent changes><aging induced alterations><aging induced changes><aging related alterations><aging related changes><aging specific alterations><aging specific changes><alterations with age><amyloid beta clearance><amyloid beta peptide clearance><brain MR imaging><brain MRI><brain abnormalities><brain atrophy><brain blood dynamics><brain magnetic resonance imaging><brain vascular disease><brain vascular dysfunction><brain visualization><cardiovascular imaging><cardiovascular risk><cardiovascular risk factor><cerebral><cerebral MR imaging><cerebral MRI><cerebral atrophy><cerebral hemodynamics><cerebral magnetic resonance imaging><cerebral vascular><cerebral vascular disease><cerebral vascular dysfunction><cerebro-vascular><cerebrovascular><cerebrovascular dysfunction><changes with age><circulatory system><cortical atrophy><dementia risk><design><designing><developmental><diagnostic tool><doctoral student><four dimensional MR imaging><four dimensional MRI><four dimensional flow><four dimensional magnetic resonance imaging><heavy metal Pb><heavy metal lead><hemodynamics><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improvements in QOL><improvements in quality of life><innovate><innovation><innovative><insight><intracranial vascular dysfunction><lack of physical activity><later in life><later life><malleable risk><mid life><mid-life><middle age><middle aged><midlife><modifiable risk><natural aging><neural imaging><neuro-imaging><neuroimaging><neurological imaging><neuronal><new approaches><normal aging><normative aging><novel><novel approaches><novel strategies><novel strategy><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><physical inactivity><pilot study><post-doc><post-doctoral><post-doctoral trainee><prevent><preventing><primary degenerative dementia><programs><quality of life improvement><research associates><risk factor for dementia><risk for dementia><senile dementia of the Alzheimer type><three dimensional><tool><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrei Maiseyeu

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Exploratory lead · 42/100

Likely hiring

Active award

$94,385

FY 2026

Project Title

Targets and targeting of immunometabolism in chronic PM2.5 exposure

Grant Number:

3R01ES033670-05S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/7/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary PM2.5 is a leading global risk factor for morbidity and mortality and is the leading environmental factor implicated in cardiovascular disease. Recent data suggest that PM2.5 and/or traffic-related air pollutants may play a role in chronic diseases such as Type 2 diabetes mellitus, t...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sanjay Rajagopalan

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Exploratory lead · 42/100

Likely hiring

Active award

$94,385

FY 2026

Project Title

Targets and targeting of immunometabolism in chronic PM2.5 exposure

Grant Number:

3R01ES033670-05S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/7/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary PM2.5 is a leading global risk factor for morbidity and mortality and is the leading environmental factor implicated in cardiovascular disease. Recent data suggest that PM2.5 and/or traffic-related air pollutants may play a role in chronic diseases such as Type 2 diabetes mellitus, t...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrew John Karter

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$370,000

FY 2026

Project Title

Evidence-Based Targets for Continuous Glucose Monitoring Metrics in Adults with Type 1 Diabetes

Grant Number:

1R56DK141601-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract: Robust evidence supports the use of continuous glucose monitoring (CGM) to assess glycemic control and inform clinical decisions in adults with type 1 diabetes (T1D). The voluminous raw CGM data (glucose reading every few minutes) is summarized into 8 standard CGM metrics (e.g., time in ra...

Research Terms

<21+ years old><Acute><Adult><Adult Human><Age><American><Blood Vessels><Brittle Diabetes Mellitus><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Clinical><Complication><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Acidosis><Diabetic Complications><Diabetic Ketoacidosis><Diabetic Ketosis><Disease Frequency Surveys><Electronic Health Record><Equilibrium><Event><Expert Opinion><Foundations><Future><Glucose><Goals><Guidelines><Heart Vascular><Hemoglobin><Hypoglycemia><IDDM><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Link><Measures><Metabolic><Microvascular Dysfunction><Modeling><Observational Study><Outcome><Patient-Centered Care><Patients><Persons><Precision care><Public Health><QOL><Quality of life><Reading><Recommendation><Research><Risk><Safety><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Time><Translational Research><Translational Science><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Work><adulthood><ages><balance><balance function><cardiovascular disorder><causal diagram><causal model><circulatory system><clinical decision-making><clinical practice><co-morbid><co-morbidity><cohort><comorbidity><competing risk><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cross-sectional research study><diabetes><diabetes risk><diabetic ketoacidotic><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evidence base><frailty><glycemic control><high risk><high risk group><high risk individual><high risk people><high risk population><high standard><hypoglycemic><hypoglycemic episodes><improved><indexing><individualized care><individualized clinical decision><individualized decision><individualized patient care><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><machine learning based model><machine learning model><microvascular complications><microvascular disease><multi-ethnic><multiethnic><novel><observational research study><observational survey><patient centered><patient oriented><personalized care><personalized clinical decision><personalized data-driven decision><personalized decision><personalized patient care><preference><real world evidence><risk stratification><stratify risk><translation research><translational investigation><type I diabetes><type one diabetes><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kasia Joanna Lipska

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$370,000

FY 2026

Project Title

Evidence-Based Targets for Continuous Glucose Monitoring Metrics in Adults with Type 1 Diabetes

Grant Number:

1R56DK141601-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract: Robust evidence supports the use of continuous glucose monitoring (CGM) to assess glycemic control and inform clinical decisions in adults with type 1 diabetes (T1D). The voluminous raw CGM data (glucose reading every few minutes) is summarized into 8 standard CGM metrics (e.g., time in ra...

Research Terms

<21+ years old><Acute><Adult><Adult Human><Age><American><Blood Vessels><Brittle Diabetes Mellitus><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Clinical><Complication><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Acidosis><Diabetic Complications><Diabetic Ketoacidosis><Diabetic Ketosis><Disease Frequency Surveys><Electronic Health Record><Equilibrium><Event><Expert Opinion><Foundations><Future><Glucose><Goals><Guidelines><Heart Vascular><Hemoglobin><Hypoglycemia><IDDM><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Link><Measures><Metabolic><Microvascular Dysfunction><Modeling><Observational Study><Outcome><Patient-Centered Care><Patients><Persons><Precision care><Public Health><QOL><Quality of life><Reading><Recommendation><Research><Risk><Safety><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Time><Translational Research><Translational Science><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Work><adulthood><ages><balance><balance function><cardiovascular disorder><causal diagram><causal model><circulatory system><clinical decision-making><clinical practice><co-morbid><co-morbidity><cohort><comorbidity><competing risk><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cross-sectional research study><diabetes><diabetes risk><diabetic ketoacidotic><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evidence base><frailty><glycemic control><high risk><high risk group><high risk individual><high risk people><high risk population><high standard><hypoglycemic><hypoglycemic episodes><improved><indexing><individualized care><individualized clinical decision><individualized decision><individualized patient care><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><machine learning based model><machine learning model><microvascular complications><microvascular disease><multi-ethnic><multiethnic><novel><observational research study><observational survey><patient centered><patient oriented><personalized care><personalized clinical decision><personalized data-driven decision><personalized decision><personalized patient care><preference><real world evidence><risk stratification><stratify risk><translation research><translational investigation><type I diabetes><type one diabetes><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alison Huang

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$358,879

FY 2026

Project Title

Promoting Clinical and Translational Science Training and Career Development for Residents

Grant Number:

5R38HL167283-04

Activity Code:

R38

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/15/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The goal of this Stimulating Access to Research in Residency (StARR) proposal is to recruit, train, and mentor a multidisciplinary group of exceptional UCSF postgraduate resident investigators in acquiring rigorous clinical and translational research skills, conducting high-impact an...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jonathan Paul Singer

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$358,879

FY 2026

Project Title

Promoting Clinical and Translational Science Training and Career Development for Residents

Grant Number:

5R38HL167283-04

Activity Code:

R38

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/15/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The goal of this Stimulating Access to Research in Residency (StARR) proposal is to recruit, train, and mentor a multidisciplinary group of exceptional UCSF postgraduate resident investigators in acquiring rigorous clinical and translational research skills, conducting high-impact an...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Katherine Ann Gallagher

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$194,949

FY 2026

Project Title

Translational research training in cardiovascular science

Grant Number:

5T32HL166130-04

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

12/1/2022

End Date:

11/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Research in cardiovascular science is rapidly progressing, as cardiovascular disease remains the largest cause of mortality and morbidity in the United States, particularly as the population ages. At the same time, however, surgeon-scientists have increasing clinical respons...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PETER K HENKE

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$194,949

FY 2026

Project Title

Translational research training in cardiovascular science

Grant Number:

5T32HL166130-04

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

12/1/2022

End Date:

11/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Research in cardiovascular science is rapidly progressing, as cardiovascular disease remains the largest cause of mortality and morbidity in the United States, particularly as the population ages. At the same time, however, surgeon-scientists have increasing clinical respons...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Taylor Coughlin

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$42,479

FY 2026

Project Title

Characterization of Nrac, a Novel Cardiac and Adipose Enriched Microprotein

Grant Number:

5F31HL178081-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/22/2024

End Date:

12/21/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Obesity is a widespread health concern impacting millions of individuals and is strongly associated with increased risk of cardiovascular disease (CVD). Despite advancements in understanding the metabolic implications of obesity, the connection between lipid droplet (LD) dynamics and...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eunice Oribamise

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$35,637

FY 2026

Project Title

Neuroinflammation as a mediator of the exaggerated Piezo2 and Exercise Pressor Reflex in Peripheral Artery Disease

Grant Number:

5F31HL175929-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

3/5/2025

End Date:

3/4/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary Peripheral artery disease (PAD) results in the progressive reduction of blood flow to peripheral body parts including the lower limbs. The resulting ischemic muscle triggers an increased arterial pressure during lower limb movements that is due to an exaggerated exercise pressor refl...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

EVELYN A BATES

UNIVERSITY OF KENTUCKY, LEXINGTON, KY

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$35,518

FY 2026

Project Title

PPARgamma Coregulators in Rosiglitazone-Induced Cardiovascular Disease

Grant Number:

5F31HL175979-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Summary Rosiglitazone (Rosi) treats type 2 diabetes (T2D) and effectively lowers blood glucose via the nuclear receptor PPARγ activation. Rosi has been reduced in use due to it inducing congestive heart failure (CHF). PPARγ is a ligand-activated transcription factor that is highly expressed in adipo...

Research Terms

<2,4-thiazolidinedione><A-FABP><Adipocytes><Adipose Cell><Adipose tissue><Adult-Onset Diabetes Mellitus><Automobile Driving><Avandia><BP reduction><Basal Transcription Factor><Basal transcription factor genes><Binding Proteins><Bioinformatics><Biological Function><Biological Process><Blood Glucose><Blood Plasma Volume><Blood Sugar><Body Tissues><Calories><Cardiac><Cardiac Failure Congestive><Cardiac Muscle Cells><Cardiac Myocytes><Cardiocyte><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Categories><Cell Communication and Signaling><Cell Signaling><ChIP Sequencing><ChIP-seq><ChIPseq><Chronic><Code><Coding System><Complex><Computer software><Congestive Heart Failure><Data><Data Analyses><Data Analysis><Development><Diet><Disease><Disorder><Dropsy><Drugs><Edema><Endocrine Gland Secretion><FABP4><FABP4 gene><FDA approved><Fat Cells><Fat-Restricted Diet><Fats><Fatty Acid Binding Protein 4, Adipocyte><Fatty Acids><Fatty Tissue><Fatty acid glycerol esters><Fellowship><Female><Foundations><Future><Gene Action Regulation><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Gene Targeting><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Transcription><Genome><Glitazones><Goals><Groups at risk><HLA-DR Associated Protein II><Heart><Heart Decompensation><Heart Muscle Cells><Heart Vascular><Heart failure><Heart myocyte><Heterocyclic Compounds><Hormones><Humulin R><Hydrops><IGAAD><Image><Inflammation><Inflammatory><Inhibitor of GZMA-Activated DNase><Insulin><Insulin Resistance><Intracellular Communication and Signaling><Investigators><Ketosis-Resistant Diabetes Mellitus><Kinases><Knock-out><Knockout><Lead><Leanness><Ligand Binding><Ligand Binding Protein><Ligand Binding Protein Gene><Ligands><Link><Lipocytes><Low-Fat Diet><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Measures><Medication><Messenger RNA><Metabolic Diseases><Metabolic Disorder><Methods><Mice><Mice Mammals><Murine><Mus><Myocardial depression><Myocardial dysfunction><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nuclear Receptors><Obese Mice><Obesity><Outcome><PAI-1><PAI1><PLANH1><PPAR><PPAR gamma><PPAR-g><PPAR-γ><PPARgamma><PPARγ><Pathogenesis><Pathway interactions><Pb element><People at risk><Peripheral><Peroxisome Proliferative Activated Receptor Gamma><Peroxisome Proliferator-Activated Receptor gamma><Peroxisome Proliferator-Activated Receptor γ><Peroxisome Proliferator-Activated Receptors><Persons><Persons at risk><Pharmaceutical Preparations><Phosphatase 2A Inhibitor I2PP2A><Phosphotransferase Gene><Phosphotransferases><Pioglitazone><Plasma Volume><Plasminogen Activator Inhibitor 1><Populations at Risk><Prevention><Protein Binding><Proteins><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Regulation><Repression><Research><Research Personnel><Researchers><Response Elements><Role><SET Translocation Inhibitor-2 of Protein Phosphatase-2A><Scientist><Serine or Cysteine Proteinase Inhibitor Clade E Member 1><Set protein><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Software><Stable Diabetes Mellitus><Stimulus><Swelling><T2 DM><T2D><T2DM><Technology><Template Activating Factor I Beta><Therapeutic><Therapeutic Hormone><Thesaurismosis><Thiazolidinedione Receptor><Thiazolidinediones><Thinking><Thinness><Time><Tissues><Training><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Transphosphorylases><Type 1 Plasminogen Activator Inhibitor><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Work><Writing><adipose><adiposity><adult onset diabetes><biological signal transduction><blood pressure reduction><bound protein><calorie><cardiac dysfunction><cardiac failure><cardiac function><cardiomyocyte><cardiovascular disorder><career><career development><chromatin immunoprecipitation coupled with sequencing><chromatin immunoprecipitation followed by sequencing><chromatin immunoprecipitation with sequencing><chromatin immunoprecipitation-seq><chromatin immunoprecipitation-sequencing><chronic heart failure><circulatory system><co-repressor><corepressor><corpulence><data interpretation><developmental><diets><driving><drug/agent><experience><falls><feeding><function of the heart><gene co-repressor><gene corepressor><genetic co-repressor><genetic corepressor><heart dysfunction><heart function><heavy metal Pb><heavy metal lead><high risk><imaging><improved><insulin resistant><insulin tolerance><intercalation><ketosis resistant diabetes><lower BP><lower blood pressure><lowers blood pressure><mRNA><male><maturity onset diabetes><metabolism disorder><ob/ob mouse><pathway><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><promoter><promotor><receptor binding><receptor bound><reduce BP><reduce blood pressure><reduction in BP><reduction in blood pressure><rosiglitazone><social role><therapeutic target><thiazolidinedione><thoughts><transcription factor><transcriptome sequencing><transcriptomic sequencing><type 2 DM><type II DM><type two diabetes><uptake><white adipose tissue><yellow adipose tissue><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Helen Schmidt

TEMPLE UNIV OF THE COMMONWEALTH, PHILADELPHIA, PA

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$35,367

FY 2026

Project Title

Friends are good for the heart: Investigating neurocognitive mechanisms underlying successful social learning that can reduce loneliness and associated cardiovascular diseases

Grant Number:

5F31HL173957-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

9/30/2024

End Date:

12/20/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY / ABSTRACT Many major life transitions, such as starting a new job or switching schools, involve learning new social structures. Successfully learning these structures is critically important for feeling a sense of belonging, improving academic or job performance, increasing well-be...

Research Terms

<18 year old><18 years of age><Address><Apoplexy><Behavioral><Biological><Brain><Brain Nervous System><Brain Vascular Accident><Cardiac Chronotropism><Cardiac health><Cardiovascular Diseases><Career Choice><Career Path><Cell Communication and Signaling><Cell Signaling><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Community Integration><Data><Data Collection><Decision Making><Development><Early Intervention><Empirical Research><Encephalon><Enrollment><Evaluation><Failure><Feeling><Friends><Friendships><Functional MRI><Functional Magnetic Resonance Imaging><Health><Heart><Heart Rate><Heart health><Hypertension><Individual><Individual Differences><Intervention><Intracellular Communication and Signaling><Jobs><Knowledge><Learning><Life><Loneliness><Longitudinal Studies><Longitudinal Surveys><Measures><Mental Health><Mental Hygiene><Mentorship><Methods><Modeling><Multivariate Analyses><Multivariate Analysis><Names><Neurocognitive><Obesity><Occupations><Outcome><Participant><Pattern><Performance at work><Personal Satisfaction><Persons><Physiologic><Physiological><Prefrontal Cortex><Premature Mortality><Prevention><Process><Professional Positions><Psyche structure><Psychological Health><Questionnaires><Reporting><Research><Rest><Retirement><Risk><Risk Reduction><Scanning><Schools><Signal Transduction><Signal Transduction Systems><Signaling><Social Environment><Social Network><Social isolation><Social support><Stretching><Stroke><Structure><Students><Survey Instrument><Surveys><Survivors><Techniques><Television><Testing><Time><Training><United States><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Ventral Striatum><Work><adiposity><age 18><age 18 years><analytical method><biologic><biological signal transduction><brain attack><cardiac disease risk><cardiac disorder risk><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><career aspiration><career interest><career pathway><career track><cerebral vascular accident><cerebrovascular accident><cohort><corpulence><developmental><disease risk><disorder risk><early adulthood><eighteen year old><eighteen years of age><emerging adult><enroll><experience><experiment><experimental research><experimental study><experiments><fMRI><feelings><heart disease risk><heart disorder risk><heart rate variability><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><interest><job performance><life span><lifespan><lonely><long-term study><longitudinal outcome studies><longitudinal research study><member><mental><name><named><naming><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><novel><physical conditioning><physical health><predict responsiveness><predicting response><programs><protective effect><psychologic><psychological><public health priorities><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><retirements><risk-reducing><social><social climate><social context><social integration><social learning><social structural><social structure><social support network><socio-structural><socioenvironment><socioenvironmental><sociostructural><stroked><strokes><success><undergrad><undergraduate><undergraduate student><well-being><wellbeing><work performance>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Elva M Arredondo

SAN DIEGO STATE UNIVERSITY, SAN DIEGO, CA

Exploratory lead · 38/100

Very recent

Active award

Career award

$114,684

FY 2026

Project Title

Mentoring trainees from diverse backgrounds in community engaged research to promote cardiovascular health

Grant Number:

5K24HL173681-03

Activity Code:

K24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract: Dr. Arredondo is a professor of psychology at San Diego State University with an excellent track record of conducting NIH-funded patient-oriented research. The K24 will provide Dr. Arredondo with protected time to mentor trainees from under-represented groups who are at different stages of...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael D. Green

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 38/100

Very recent

Active award

Career award

$84,581

FY 2026

Project Title

Assessing the Impact of Patient-Provider Interactions on the Cardiovascular and Cognitive Health of Aging Adults

Grant Number:

4K00AG088695-03

Activity Code:

K00

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2024

End Date:

2/28/2030

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The adverse effects of poor treatment in healthcare settings on cognitive impairment are poorly understood, particularly among aging Americans. My F99 research established an association between these experiences and adverse cardiovascular events. Cardiovascular events are themselves known risk fact...

Research Terms

<21+ years old><AD and related dementia><AD related dementia><ADRD><Address><Adherence><Adult><Adult Human><Adverse effects><Affect><Age><Aging><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Amentia><American><Award><Behavior><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complex><Continuity of Care><Continuity of Patient Care><Continuum of Care><Data><Data Analyses><Data Analysis><Dementia><Diagnosis><Disturbance in cognition><Event><Face><Foundations><Goals><Health><Health Care><Health Priorities><Health and Retirement Study><Health system><Healthy diet><Heart><Heart Vascular><Hypertension><Impaired cognition><Insurance Coverage><Insurance Status><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><K-Awards><K-Series Research Career Programs><Knowledge><Leadership><Life Cycle><Life Cycle Stages><Measures><Medical><Mentors><Mission><Modeling><Multidisciplinary Collaboration><Multidisciplinary Research><Myocardial Infarct><Myocardial Infarction><Obesity><Outcome><Patients><Pattern><Persons><Phase><Policies><Postdoc><Postdoctoral Fellow><Public Health Schools><QOC><Quality of Care><R-Series Research Projects><R01 Mechanism><R01 Program><Recommendation><Reporting><Research><Research Associate><Research Career Program><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Training><Researchers><Risk><Risk Factors><Role><Scientist><Shapes><Smoking><Societies><Statistical Methods><Structure><Survival Analyses><Survival Analysis><System><Testing><Time><Training><Training Programs><Trust><United States><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><adiposity><adulthood><aged><ages><balanced diet><barrier to care><barrier to health care><barrier to treatment><cardiac infarct><cardiovascular health><cardiovascular risk><cardiovascular risk factor><career><circulatory system><clinical risk><cognitive dysfunction><cognitive loss><coronary attack><coronary infarct><coronary infarction><corpulence><cost><data interpretation><dementia risk><design><designing><experience><faces><facial><falls><good diet><health and care delivery><health care delivery><health care quality><health care settings><health data><health delivery systems><health services delivery><heart attack><heart infarct><heart infarction><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><insight><investigate longitudinal><later in life><later life><life course><longitudinal investigation><longitudinal research><malleable risk><methods to study multiple-level influences><mid life><mid-life><middle age><middle aged><midlife><modifiable risk><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><multimorbidity><multiple chronic conditions><novel><obstacle to care><obstacle to health care><older adult><older adulthood><patient clinician engagement><patient clinician interaction><patient clinician relationship><patient doctor engagement><patient doctor interaction><patient doctor relationship><patient physician engagement><patient physician interaction><patient physician relationship><patient provider engagement><patient provider interaction><patient provider relationship><patient-clinician communication><patient-doctor communication><patient-provider communication><poor health outcome><post-doc><post-doctoral><post-doctoral trainee><pre-doc><pre-doctoral><reduced health outcome><research associates><risk factor for dementia><risk for dementia><risk for stroke><risk of stroke><skills><social role><statistic methods><stressor><stroke risk><stroke-like challenge><stroke-like condition><stroke-like disorder><stroke-like outcome><stroke-like symptoms><stroke-like syndrome><study longitudinal><survey longitudinal><worse health outcome>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ying Zhang

UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OKLAHOMA CITY, OK

Exploratory lead · 34/100

Large award

Active award

$1,885,204

FY 2026

Project Title

STRONG HEART STUDY (SHS)- COORDINATING CENTER (CC)- TASK ORDER 001

Grant Number:

75N92019D00027-P00014-759201900074-1

Activity Code:

N01

Mechanism:

R and D Contracts

Agency:

NIH

Start Date:

2/15/2019

End Date:

2/14/2027

Why this may be worth a closer look

• Large budget suggests more room for personnel or project growth.

Project Abstract

The Strong Heart Study (SHS) is a longitudinal observational study of two combined cohorts followed prospectively: the original SHS cohort recruited in 1989 to 1991 and a Strong Heart Family Study (SHFS) cohort recruited in 1998 to 1999. The original and family cohorts together form the largest, mu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Courtney Anne Bouchet

COLORADO STATE UNIVERSITY, FORT COLLINS, CO

Exploratory lead · 34/100

Training-friendly

Active award

$82,540

FY 2026

Project Title

Cortical-hypothalamic control of the cardiovascular consequences of stress

Grant Number:

5F32HL172693-03

Activity Code:

F32

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/15/2023

End Date:

12/14/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary Cardiovascular diseases are the leading cause of death globally and pathologies are exacerbated by chronic stress. Stress-cardiovascular comorbidities are more prevalent in females, however, the neurobiological mechanisms linking stress to cardiovascular outcomes are not well unders...

Research Terms

<4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><Affective Disorders><Aminalon><Aminalone><Anatomic Sites><Anatomic structures><Anatomy><Animals><Architecture><Blood Pressure><Blood Vessels><Brodmann's area><CNS plasticity><Cardiac Chronotropism><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Pathology><Cardiovascular Physiology><Cardiovascular system><Cause of Death><Cell Communication and Signaling><Cell Signaling><Chronic><Chronic stress><Common Rat Strains><Data><Deep Brain Stimulation><Differences between sexes><Differs between sexes><Dimensions><Electrophysiology><Electrophysiology (science)><Endothelium><Engineering / Architecture><Ensure><Fellowship><Female><GABA><Gene Transcription><Genetic Transcription><Glutamates><Heart Rate><Heart Vascular><Human><Hypothalamic structure><Hypothalamus><Impairment><Incidence><Intracellular Communication and Signaling><L-Glutamate><Laboratories><Learning><Link><Mediating><Mental Depression><Mentors><Mentorship><Microvascular Dysfunction><Modern Man><Mood Disorders><Myography><Nerve Cells><Nerve Unit><Neural Cell><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurocyte><Neuroendocrine><Neuroendocrine System><Neuronal Plasticity><Neurons><Neurophysiology / Electrophysiology><Neurosecretory Systems><Outcome><Output><Paraventricular Hypothalamic Nucleus><Pathology><Pharmacological Study><Pharmacology Study><Physiologic><Physiologic pulse><Physiological><Postdoc><Postdoctoral Fellow><Posterior Hypothalamic Region><Posterior Hypothalamus><Predictive Factor><Predisposition><Prefrontal Cortex><Psychosocial Stress><Pulse><RNA Expression><Rat><Rats Mammals><Rattus><Reporting><Research><Research Associate><Resistance><Risk><Role><Running><Sex Differences><Sexual differences><Signal Transduction><Signal Transduction Systems><Signaling><Slice><Stress><Susceptibility><Synapses><Synaptic><Synaptic plasticity><Tachycardia><Testing><Training><Transcription><Transgenic Organisms><Translating><Vascular Diseases><Vascular Disorder><Viral><Woman><Women's prevalence><Work><acute stress><arterial stiffening><arterial stiffness><arteriole><artery stiffening><artery stiffness><biological adaptation to stress><biological signal transduction><blood pressure elevation><blood vessel disorder><cardiovascular disorder><cardiovascular effects><cardiovascular function><cardiovascular health><cardiovascular risk><cardiovascular risk factor><career><career development><cell type><central nervous system plasticity><circulatory system><co-morbid><co-morbidity><comorbidity><depression><electrophysiological><elevated blood pressure><excitatory neuron><experiment><experimental research><experimental study><experiments><female prevalence><focus on male><focused on men><gamma-Aminobutyric Acid><glutamatergic><hypothalamic><in vivo><increase in blood pressure><increased blood pressure><inhibitory neuron><knock-down><knockdown><knowledge base><male><male focused><male specific><male targeted><microvascular complications><microvascular disease><neural circuit><neural circuitry><neural plasticity><neurobiological mechanism><neurocircuitry><neuronal><neuroplastic><neuroplasticity><optogenetics><paraventricular nucleus><pharmacologic><post-doc><post-doctoral><post-doctoral trainee><postsynaptic><pressure><presynaptic><prevalence among females><prevalence among women><prevalence in females><prevalence in women><prevalent among females><prevalent among women><prevalent in females><prevalent in women><prevent><preventing><programs><reactioncrisis><research associates><resilience><resilient><resistant><response><restraint><sex><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><skills><social role><stress response><stressreaction><synapse><synaptic circuit><synaptic circuitry><targeted to men><transgenic><vascular><vascular dysfunction><vasculopathy><γ-Aminobutyric Acid><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Larissa Benjamin

UNIVERSITY OF CALIFORNIA BERKELEY, BERKELEY, CA

Exploratory lead · 34/100

Training-friendly

Active award

$47,105

FY 2026

Project Title

Understanding the Macrosocial Drivers of Cardiovascular Health in the Rural South

Grant Number:

5F31MD020261-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

11/1/2024

End Date:

10/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary Rural Americans currently face a significant health crisis marked by a heightened prevalence of cardiovascular disease (CVD), the leading cause of mortality in the United States, responsible for one-third of all deaths and claiming a life every 34 seconds. Although this rural health ...

Research Terms

<21+ years old><Accounting><Address><Adult><Adult Human><Affect><Age><Alabama><Appalachia><Appalachian><Appalachian Region><Area><Automobile Driving><Black><Black race><Blood Pressure><Cardiovascular Diseases><Censuses><Cessation of life><Complex><Data><Death><Delta Region of Mississippi><Diabetes Mellitus><Disparities><Disparity><Economics><Environment><Environmental Pollution><Ethnic Group><Ethnic Origin><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity><Ethnicity People><Ethnicity Population><Face><Fellowship><Goals><Health><Health Inequity><High Prevalence><Impoverished><Incidence><Individual><Inequalities in Health><Inequities in Health><Inequity><Injury><Kentucky><Knowledge><Life><Link><Longitudinal Studies><Longitudinal Surveys><Louisiana><Measures><Mentorship><Mississippi><Mississippi Delta><Natural Disasters><Nature><Neighborhoods><Obesity><Outcome><Persons><Phase><Population><Poverty><Prevalence><Process><Public Health Practice><Public Health Schools><Race><Races><Research><Risk><Risk Factors><Role><Rural><Rural Community><Rural Health><SES disparity><Shapes><Social isolation><Socio-economic status><Socioeconomic Status><Stress><Stroke Belt><United States><Variant><Variation><Work><adiposity><adulthood><aged><ages><cardiometabolic><cardiometabolism><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><career><cohort><corpulence><deprivation><diabetes><disparities in race><disparity due to race><disparity in ethnic><driving><economic><environmental contamination><ethnic based disparity><ethnic disadvantage><ethnic disparity><ethnic inequality><ethnic inequity><ethnic subgroup><ethnicity disparity><ethnicity group><faces><facial><health equity><health inequalities><indexing><inequality due to race><inequity due to race><injuries><long-term study><longitudinal outcome studies><longitudinal research study><mortality><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial><racial background><racial disparity><racial inequality><racial inequity><racial minority group><racial minority individual><racial minority people><racial minority population><racial origin><racially unequal><recruit><residence><residential building><residential segregation><residential site><rural Americans><rural area><rural counties><rural dwelling><rural households><rural location><rural region><rural residence><rurality><segregation><social><social health determinants><social role><social vulnerability><socio-economic><socio-economic disparity><socio-economic inequality><socio-economic inequity><socio-economic position><socio-economically><socioeconomic disparity><socioeconomic inequality><socioeconomic inequity><socioeconomic position><socioeconomically><socioeconomics><urban area><urban environment><urban location><urban region><urban setting>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kenneth Eugene Remy

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Exploratory lead · 30/100

Very recent

Active award

$235,500

FY 2026

Project Title

Investigating Plasma Cell-Free Hemoglobin as a Driver of Cardiovascular Disease Risk in HIV-Positive Individuals

Grant Number:

1R21AI191916-01A1

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/17/2026

End Date:

3/31/2028

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY: People with HIV (PWH) face persistent low-grade inflammation, pro-active blood clotting mechanisms, and a twofold higher risk of cardiovascular disease despite effective anti-HIV treatments. A recent clinical trial showed that statins reduce cardiovascular disease risks by up to 35%...

Research Terms

<(TNF)-α><2-Propanone><AIDS Virus><AIDS/HIV><Acceleration><Acetone><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Active Oxygen><Address><Adhesion Molecule><Age><Anemia><Aorta><Assay><Automobile Driving><Autoregulation><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Beta Proprotein Interleukin 1><Binding><Binding Proteins><Bioassay><Biological Assay><Blood Clotting><Blood Plasma><Blood Plasma Cell><Blood Platelets><Blood Vessels><Blood coagulation><Blood erythrocyte><CD106><CD106 Antigens><CD62P Antigens><Cachectin><Cardiovascular Diseases><Case-Comparison Studies><Case-Compeer Studies><Case-Referent Studies><Case-Referrent Studies><Case/Control Studies><Cell Adhesion Molecule Gene><Cell Adhesion Molecules><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic><Clinical><Clinical Treatment><Clinical Trials><Co-culture><Cocultivation><Coculture><Coculture Techniques><Cytolysis><Data><Density Gradient Centrifugation><Density Gradient Fractionation><Diabetes Mellitus><Dimethyl formaldehyde><Disease><Disorder><Dysfunction><EDRF Synthase><ELISA><Endothelial Cells><Endothelium><Endothelium-Derived Growth Factor Synthase><Enzyme-Linked Immunosorbent Assay><Erythrocytes><Erythrocytic><Event><Exclusion><Exhibits><F8VWF><Face><Ferroprotoporphyrin><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Free Radicals><Functional disorder><Future><GM-CSF><GMP-140><Gel><Gene Expression><Generations><Genes><Genus Hippocampus><Granulocyte-Macrophage Colony-Stimulating Factor><Guanylyl Cyclase-Activating Factor Synthase><HIV><HIV individuals><HIV infected individuals><HIV infected persons><HIV intervention><HIV people><HIV positive individuals><HIV positive people><HIV therapeutic><HIV therapy><HIV treatment><HIV-1 intervention><HIV-1 therapeutic><HIV-1 therapy><HIV-1 treatment><HIV/AIDS><HPGF><Hb SS disease><HbSS disease><Heme><Hemoglobin><Hemoglobin S Disease><Hemoglobin concentration result><Hemoglobin sickle cell disease><Hemoglobin sickle cell disorder><Hemolytic Anemia><Hepatocyte-Stimulating Factor><Histamine-Producing Cell-Stimulating Factor><Homeostasis><Homolog of Drosophila TOLL><Human><Human Immunodeficiency Virus therapy><Human Immunodeficiency Virus treatment><Human Immunodeficiency Viruses><Hybridoma Growth Factor><Hyperlipemia><Hyperlipidemia><Hypertension><IFN-beta 2><IFNB2><IL-1 beta><IL-1 β><IL-1-b><IL-1β><IL-6><IL1-Beta><IL1-β><IL1B Protein><IL1F2><IL1β><IL6 Protein><INCAM-110><Immune Cell Activation><Immunochemical Immunologic><Immunofluorescence Microscopy><Immunologic><Immunological><Immunologically><Immunologics><Individual><Inducible Cell Adhesion Molecule 110><Inflammation><Inflammatory><Integrins><Integrins Extracellular Matrix><Interleukin 1beta><Interleukin-1 beta><Interleukin-1β><Interleukin-6><Intracellular Communication and Signaling><Knowledge><LAV-HTLV-III><LECAM-3><Ligand Binding Protein><Ligand Binding Protein Gene><Lymphadenopathy-Associated Virus><Lysis><MGI-2><Macrophage-Derived TNF><Marrow erythrocyte><Marrow platelet><Metabolic><Methods><Modeling><Modern Man><Molecular Interaction><Molgramostin><Monocyte-Derived TNF><Myeloid Differentiation-Inducing Protein><NIH><NO Synthase><National Institutes of Health><Nitric Oxide Synthase><Nitric-Oxide Synthetase><Oxygen Radicals><P-Selectin><PLWH><PWH><Participant><Pathogenesis><Persons><Phenotype><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Plasma><Plasma Cells><Plasma Serum><Plasmacytes><Plasmacytoma Growth Factor><Platelet Activation><Platelet alpha-Granule Membrane Protein><Platelets><Population><Preinterleukin 1 Beta><Pro-Oxidants><Process><Production><Protein Binding><Protoheme><RNA Seq><RNA sequencing><RNAseq><Race><Races><Randomization trial><Reactive Oxygen Species><Recovery><Recycling><Red Blood Cells><Red Cell><Research><Residual><Residual state><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Ristocetin Cofactor><Ristocetin-Willebrand Factor><Sample Size><Sampling><Seahorse><Sickle Cell Anemia><Signal Transduction><Signal Transduction Systems><Signaling><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Stress><TC-GM-CSF><TLR4><TLR4 gene><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Techniques><Testing><Thrombocytes><Toll Homologue><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Tumor-Cell Human GM Colony-Stimulating Factor><United States National Institutes of Health><Universities><VCAM><VCAM-1><VWF gene><Vascular Cell Adhesion Molecule><Vascular Cell Adhesion Molecule-1><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vesicle><Virus-HIV><Width><ages><antiretroviral therapy><antiretroviral treatment><biological signal transduction><blood corpuscles><bound protein><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><case-control survey><case-controlled studies><cell adhesion protein><clinical intervention><clinical therapy><cytokine><density gradient ultracentrifugation><depository><design><designing><diabetes><driving><endothelial dysfunction><enzyme linked immunoassay><experiment><experimental research><experimental study><experiments><extracellular vesicles><faces><facial><ferroheme><flow cytophotometry><hemoglobin level><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><immune activation><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><innovate><innovation><innovative><insight><interferon beta 2><life span><lifespan><nano particle><nano-sized particle><nanoparticle><nanosized particle><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathophysiology><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><plasmocyte><prevent><preventing><protein expression><racial><racial background><racial origin><randomized trial><repository><response><semiparametric><sex><sickle cell disease><sickle cell disorder><sickle disease><sicklemia><statistical analysis><systemic inflammation><systemic inflammatory response><thrombotic><toll-like receptor 4><transcriptome sequencing><transcriptomic sequencing><translation strategy><translational approach><translational strategy><translational study><treat HIV><treat Human Immunodeficiency Virus><trial regimen><trial treatment><vWF><vascular><von Willebrand Factor><von Willebrand Protein>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Diana Martinez

ROWAN UNIVERSITY, GLASSBORO, NJ

Exploratory lead · 30/100

Very recent

Active award

$161,000

FY 2026

Project Title

The Role of Astrocytes in Circadian Control of Blood Pressure in the Nucleus of the Solitary Tract

Grant Number:

5R16GM153695-03

Activity Code:

R16

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Our 24-hour society requires an increasing number of individuals to work rotating shifts to adapt to schedules on a global scale. In the United States, 15 million people participate in some form of shift work. Shift work is associated with the risk of cardiovascular health p...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Scott A Berceli

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Exploratory lead · 30/100

Very recent

Active award

$124,346

FY 2026

Project Title

Renewal: Short-Term Training for Medical Students in Cardiovascular and Pulmonary Research

Grant Number:

5T35HL007489-43

Activity Code:

T35

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

5/1/1980

End Date:

3/31/2029

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT The University of Florida College of Medicine has a long tradition and record of accomplishments in training medical students for careers in academic medicine and research. This application is a resubmission of a competitive renewal of a T35 Grant titled “Short-Term Trainin...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Robert Maile

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Exploratory lead · 30/100

Very recent

Active award

$124,346

FY 2026

Project Title

Renewal: Short-Term Training for Medical Students in Cardiovascular and Pulmonary Research

Grant Number:

5T35HL007489-43

Activity Code:

T35

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

5/1/1980

End Date:

3/31/2029

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT The University of Florida College of Medicine has a long tradition and record of accomplishments in training medical students for careers in academic medicine and research. This application is a resubmission of a competitive renewal of a T35 Grant titled “Short-Term Trainin...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ERIKA J WOLF

VA BOSTON HEALTH CARE SYSTEM, BOSTON, MA

Exploratory lead · 30/100

Very recent

Active award

$0

FY 2026

Project Title

Traumatic Stress, Epigenetic Aging, and Cardiovascular Risk in the Million Veteran Program

Grant Number:

1I01BX006510-01A1

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

4/1/2025

End Date:

3/31/2030

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Background & Innovation: This project will make use of Million Veteran Program (MVP) data to address questions concerning the relationships between traumatic stress, epigenetic aging in DNA methylation data, and cardiovascular disease (CVD, including ischemic stroke, myocardial infarction, coronary ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Daniel T Eitzman

VETERANS HEALTH ADMINISTRATION, ANN ARBOR, MI

Exploratory lead · 30/100

Very recent

Active award

$0

FY 2026

Project Title

Traumatic Brain Injury and Vascular Disease

Grant Number:

5I01BX004836-06

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

1/1/2021

End Date:

9/30/2026

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Objective: Traumatic brain injury (TBI) is a common cause of morbidity and mortality in the veteran population. In the United States, there are an estimated 5.3 million people living with a TBI-related disability. TBI commonly leads to neurocognitive deficits, however, other systemic effects have al...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tauqeer Ali

UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OKLAHOMA CITY, OK

Exploratory lead · 28/100

Above-average budget

Active award

$848,851

FY 2026

Project Title

STRONG HEART STUDY (SHS)- FIELD CENTER (FC)- TASK ORDER 001

Grant Number:

75N92019D00028-P00011-759201900074-1

Activity Code:

N01

Mechanism:

R and D Contracts

Agency:

NIH

Start Date:

2/15/2019

End Date:

2/14/2027

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

The Strong Heart Study (SHS) is a longitudinal observational study of two combined cohorts followed prospectively: the original SHS cohort recruited in 1989 to 1991 and a Strong Heart Family Study (SHFS) cohort recruited in 1998 to 1999. The original and family cohorts together form the largest, mu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amanda Mae Fretts

MISSOURI BREAKS RESEARCH, INC., EAGLE BUTTE, SD

Exploratory lead · 28/100

Above-average budget

Active award

$821,247

FY 2026

Project Title

STRONG HEART STUDY (SHS)- FIELD CENTER, TASK ORDER 001

Grant Number:

75N92019D00029-P00017-759201900074-1

Activity Code:

N01

Mechanism:

R and D Contracts

Agency:

NIH

Start Date:

2/15/2019

End Date:

2/14/2027

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

The Strong Heart Study (SHS) is a longitudinal observational study of two combined cohorts followed prospectively: the original SHS cohort recruited in 1989 to 1991 and a Strong Heart Family Study (SHFS) cohort recruited in 1998 to 1999. The original and family cohorts together form the largest, mu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

nagendra monangi

UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OKLAHOMA CITY, OK

Exploratory lead · 26/100

Solid budget

Active award

$469,049

FY 2026

Project Title

STRONG HEART STUDY (SHS) - UNIVERSITY OF OKLAHOMA, FIELD CENTER (FC), TASK AREA C: DATA BOOK

Grant Number:

75N92019D00028-0-759202600001-1

Activity Code:

N01

Mechanism:

R and D Contracts

Agency:

NIH

Start Date:

1/12/2026

End Date:

2/14/2027

Project Abstract

The Strong Heart Study (SHS) is a longitudinal observational study of two combined cohorts followed prospectively: the original SHS cohort recruited in 1989 to 1991 and a Strong Heart Family Study (SHFS) cohort recruited in 1998 to 1999. The original and family cohorts together form the largest, mul...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kendra D Sims

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Exploratory lead · 22/100

Recent

Active award

$249,000

FY 2026

Project Title

Community Empowerment, Vascular Risk, and ADRD Disparities: Translating Research to Public Policy

Grant Number:

4R00AG083121-03

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2023

End Date:

2/28/2029

Project Abstract

By 2050, racial disparities will persist among the projected 11 million adults with Alzheimer’s Disease and Related Dementias (AD/ADRD). Prior research links factors to AD/ADRD, highlighting the need for policy solutions to mitigate the racially-patterned cardiovascular disease (CVD) burden that acc...

Research Terms

<21+ years old><AD and related dementia><AD related dementia><AD risk><AD risk factor><ADRD><Acceleration><Adult><Adult Human><Alzheimer risk factor><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimer's disease risk><American><Area><Award><Black><Black race><Blood Vessels><Boston><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Censuses><Characteristics><Clinical><Cognitive><Cohort Studies><Collaborations><Communities><Community Surveys><County><Data><Data Science><Decrease disparity><Depressed mood><Deterioration><Development><Disease><Disorder><Disparities><Disparity><Economic Factors><Economical Factors><Economics><Ensure><Event><Faculty><Foundations><Future><Goals><Health><Health Care Costs><Health Costs><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Health Policy><Health and Retirement Study><Heart Vascular><Housing><Incidence><Infrastructure><Institution><Intervention><Investigators><Investments><Joints><Knowledge><Link><Lower disparity><Machine Learning><Mediating><Mediator><Medicare><Medicare claim><Mentors><Mentorship><Modeling><Neighborhoods><Pattern><Phase><Policies><Population><Population Attributable Risks><Position><Positioning Attribute><Prevalence><Prevention><Public Health><Public Health Schools><Public Policy><Race><Races><Reasons for Geographic And Racial Differences in Stroke><Relative Risks><Research><Research Personnel><Research Resources><Researchers><Resources><Retirement><Risk><Risk Estimate><Risk Factors><Role><Sampling><Science><Social Environment><Stroke Belt><Title 18><Training><Translating><Universities><Variant><Variation><adulthood><alzheimer risk><attributable fraction><beneficiary><black/white disparity><burden of disease><burden of illness><cardiovascular disease epidemiology><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder epidemiology><cardiovascular disorder risk><cardiovascular effects><cardiovascular epidemiology><circulatory system><cohort><cohort research study><cohort survey><community empowerment><community engagement><community factor><community intervention><community level disadvantage><community level intervention><community-based intervention><community-level factor><dementia risk><demographics><depressed><developmental><disadvantaged community><disease burden><disparities in race><disparity due to race><disparity reduction><economic><empowerment><engagement with communities><health care policy><health insurance for disabled><high risk><high risk group><high risk individual><high risk people><high risk population><inequality due to race><inequity due to race><innovate><innovation><innovative><machine based learning><mitigate disparity><mortality><neighborhood barrier><neighborhood disadvantage><neighborhood-level barrier><neighborhood-level disadvantage><older adult><older adulthood><policy implication><prevent><preventing><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial><racial background><racial disparity><racial inequality><racial inequity><racial origin><racially unequal><reduce disparity><reduction in disparity><residence><residential building><residential site><retirements><risk factor for dementia><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk for dementia><risk of developing Alzheimer's><sadness><scale up><skills><social><social climate><social context><social engagement><social involvement><social participation><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><socioenvironment><socioenvironmental><success><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tetsushi Nakao

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Exploratory lead · 22/100

Recent

Active award

$249,000

FY 2026

Project Title

Using genomic modifiers to mechanistically link clonal hematopoiesis of indeterminate potential penetrance to coronary artery disease

Grant Number:

4R00HL165024-03

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2026

End Date:

2/28/2029

Project Abstract

PROJECT SUMMARY (See instructions}: Though cardiovascular disease (CVD) management has advanced, CVD remains the leading cause of premature death worldwide. As age remains the dominant factor in CVD risk and the population ages, the poorly understood age-related factors promoting CVD risk require ur...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Chengyi Tu

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Exploratory lead · 22/100

Recent

Active award

$249,000

FY 2026

Project Title

Tachycardia-induced Metabolic Remodeling Drives Cardiac Dysfunction

Grant Number:

4R00HL164962-03

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/16/2026

End Date:

1/31/2029

Project Abstract

Tachycardia, or abnormally fast heart rate, is an important risk factor for cardiovascular morbidity and mortality. Prolonged tachycardia is known to induce cardiomyopathy in patients who have no prior structural heart diseases. Moreover, transient tachycardia, frequently observed in heart failure p...

Research Terms

<3-D><3-Dimensional><3-Phosphoglyceraldehyde><3-phosphoglycerate><3D><ATP-3-phospho-D-glycerate 1-phosphotransferase><Abnormal heart structure><Acceleration><Address><Adrenergic beta-Antagonists><Adrenergic beta-Blockers><Advisory Committees><Affect><Animals><Arrhythmia><Autoregulation><Binding><Biology><Biomedical Engineering><Biopsy><CRISPR interference><CRISPR-dCas9-mediated repression><CRISPR/dCas9 interference><CRISPR/dCas9-mediated transcriptional inhibition><CRISPRi><Calcium><Canine Species><Canis familiaris><Cardiac><Cardiac Arrhythmia><Cardiac Chronotropism><Cardiac Diseases><Cardiac Disorders><Cardiac Electrophysiologic Techniques><Cardiac Electrophysiological Diagnostics><Cardiac Muscle Cells><Cardiac Myocytes><Cardiocyte><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cells><Ch'i><Chemicals><Clustered Regularly Interspaced Short Palindromic Repeats interference><Coupled><Critical Paths><Critical Pathways><Custom><D-Glucose><Data><Data Engineering><Development><Dextrose><Dogs><Dogs Mammals><Dysfunction><Enzyme Gene><Enzymes><Event><Fatty Acid Metabolism Pathway><Functional disorder><Future><G-Proteins><GAPD><GTP-Binding Proteins><GTP-Regulatory Proteins><Gene Inactivation><Gene Silencing><Genes><Genetic><Glucose><Glyceraldehyde 3-Phosphate><Glyceraldehyde-3-Phosphate Dehydrogenases><Glyceraldehydephosphate Dehydrogenase><Glycolysis><Goals><Guanine Nucleotide Coupling Protein><Guanine Nucleotide Regulatory Proteins><Heart><Heart Arrhythmias><Heart Diseases><Heart Muscle Cells><Heart Rate><Heart Vascular><Heart failure><Heart myocyte><History><Homeostasis><Human Engineering><Impairment><In Vitro><Investigators><Knowledge><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Mentors><Metabolic><Metabolic Diseases><Metabolic Disorder><Modeling><Molecular><Molecular Interaction><Morbidity><Myocardial Diseases><Myocardial Disorder><Myocardial depression><Myocardial dysfunction><Myocardiopathies><Myoglobin><Outcome><Oxidative Stress><Pathology><Pathway interactions><Patients><Phase><Phenotype><Phosphoglyceraldehyde Dehydrogenase><Phosphoglycerate Kinase><Physiologic><Physiological><Physiological Homeostasis><Physiology><Physiopathology><Play><Prognosis><Protein Cleavage><Protein Subunits><Proteins><Proteolysis><Qi><RNA Seq><RNA sequencing><RNAseq><Recording of previous events><Recovery><Regulation><Research><Research Personnel><Researchers><Risk Factors><Role><Sampling><Signal Pathway><Sum><System><Tachyarrhythmias><Tachycardia><Task Forces><Technology><Therapeutic><Therapeutic Intervention><Thesaurismosis><Tissue Engineering><Tissue Model><Training><Treatment Failure><Triosephosphate Dehydrogenase><Validation><Ventricular Dysfunction><advisory team><analysis pipeline><beta blocker><beta-Adrenergic Blocking Agents><beta-Adrenergic Receptor Blockaders><bio-engineered><bio-engineers><bioengineered tissue><bioengineering><biological engineering><canine><canine animal model><canine model><cardiac dysfunction><cardiac electrophysiology><cardiac failure><cardiac function><cardiac tissue engineering><cardiomyocyte><cardiovascular risk><cardiovascular risk factor><circulatory system><customs><design><designing><developmental><dog model><domestic dog><engineered heart tissue><engineered tissue><experience><fatty acid metabolism><feasibility testing><function of the heart><global gene expression><global transcription profile><glyceraldehyde phosphate><glycerate 3-phosphate><heart disorder><heart dysfunction><heart electrophysiology><heart function><histories><human data><iPS><iPS biology><iPSC><iPSC biology><iPSCs><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cell biology><inducible pluripotent cell><inducible pluripotent stem cell><intervention therapy><metabolic profile><metabolism disorder><metabolism measurement><metabolomics><metabonomics><mortality><multiomics><multiple omics><myocardium disease><myocardium disorder><novel><panomics><pathophysiology><pathway><progenitor biology><progenitor cell biology><repressing CRISPR-dCas9 system><skills><social role><stem and progenitor biology><stem cell biology><structural cardiac abnormality><structural cardiac anomaly><structural cardiac defect><structural heart condition><structural heart defect><structural heart disease><tachyrhythmia><therapy failure><three dimensional><transcriptional silencing><transcriptome><transcriptome profiling><transcriptome sequencing><transcriptomic profiling><transcriptomic sequencing><transcriptomics><validations>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amanda K Marma

LURIE CHILDREN'S HOSPITAL OF CHICAGO, CHICAGO, IL

Exploratory lead · 22/100

Recent

Active award

$193,674

FY 2026

Project Title

Developing a Novel Adolescent Cardiovascular Health Promotion Program (CPP)

Grant Number:

5R34HL171722-03

Activity Code:

R34

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2027

Project Abstract

PROJECT SUMMARY / ABSTRACT Cardiovascular disease (CVD) risk factors in adolescence are common and robustly associated with adult CVD events. Clinical capacity for intensive behavioral intervention is insufficient to meet demand, and moreover, standard behavioral interventions have had limited effic...

Research Terms

<12-20 years old><18 year old><18 years of age><21+ years old><Adherence><Adolescence><Adolescent><Adolescent Behavior><Adolescent Youth><Adult><Adult Human><Anxiety><Attention><BMI><BMI percentile><BMI z-score><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Benchmarking><Best Practice Analysis><Body mass index><Cannot see a future><Cardiovascular Diseases><Childhood><Clinical><Clinical Trials><Conditioning Therapy><Data><Development><Diagnostic><Dimensions><Dose><Emotional><Emotional disorder><Emotions><Enrollment><Equilibrium><Evaluation><Event><Feeling hopeless><Feels there is no future><Foundations><Future><Goals><Guidelines><Health><Health Promotion><Health behavior><Impairment><Intervention><Interview><Leanness><Loss of hope for the future><Methods><Motivation><NHLBI><National Heart, Lung, and Blood Institute><Negative about the future><Neurobiology><No hope for the future><Obesity><Obesity associated cardiovascular disease><Obesity related cardiovascular disease><Personal awareness><Phase><Population><Preparation><Preventive><Process><Protocol><Protocols documentation><Psychologist><Quetelet index><Randomized><Recommendation><Regulation><Research><Risk><Risk Factors><Salutogenesis><Self Perception><Self image><Self view><Societies><Structure><Target Populations><Teen><Teenagers><Testing><Thinness><Work><Youth><Youth 10-21><academic intervention><acceptability and feasibility><adiposity><adolescence (12-20)><adulthood><age 18><age 18 years><age group><arm><balance><balance function><behavior change><behavior change wheel><behavior intervention><behavior study><behavioral intervention><behavioral study><benchmark><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><co-morbid><co-morbidity><community advisory board><community advisory committee><community advisory panel><comorbidity><corpulence><cost><delivered remotely><developmental><diabetes prevention program><digital><effectiveness testing><efficacy trial><eighteen year old><eighteen years of age><emotion regulation><emotional regulation><empowerment><enroll><experience><health related behavior><healthy lifestyle><hopelessness><implementation design><implementation research design><improved><insight><interest><intervention refinement><iterative design><juvenile><juvenile human><mortality><multiphase optimization strategy><natives><neurobiological><novel><pediatric><person centered><pilot test><pilot trial><preference><premature><prematurity><preparations><prevent><preventing><programs><promoting health><prototype><psychosocial stresses><psychosocial stressors><randomisation><randomization><randomly assigned><recruit><remote delivery><response><self awareness><self knowledge><teen years><teenage><theories><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lee H Harrison

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 22/100

Recent

Active award

$157,225

FY 2026

Project Title

Pitt-Mozambique Training Program (Pitt-MozHRTP) in SARS-CoV-2, Cardiovascular Disease, and Diabetes in People with HIV

Grant Number:

3D43TW011827-05S1

Activity Code:

D43

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/2/2022

End Date:

1/31/2027

Project Abstract

The overall mission of Pitt-MozHRTP is to provide HIV research training opportunities for investigators at Polana Caniço Health Research and Training Center (Centro de Investigação e Treino em Saúde da Polana Caniço, CISPOC) - a key research institution of the Mozambique National Institute of Health...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><AIDS Virus><AIDS focused research><AIDS related research><AIDS research><AIDS science><AIDS specific research><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Area><COVID-19 virus><COVID19 virus><Cardiovascular Diseases><CoV-2><CoV2><Collaborations><Country><Development><Diabetes Mellitus><Doctor of Philosophy><Fellowship><Fostering><Generations><Goals><HIV><HIV focused research><HIV individuals><HIV infected individuals><HIV infected persons><HIV investigation><HIV people><HIV positive individuals><HIV positive people><HIV related research><HIV research><HIV science><HIV specific research><Health><Human Immunodeficiency Viruses><Institution><Investigation on HIV><Investigators><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Master of Science><Master's Degree><Mentors><Mission><Mozambique><NIH><National Institutes of Health><PLWH><PWH><Ph.D.><PhD><Portuguese East Africa><Research><Research Personnel><Researchers><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Site><South Africa><Training><Training Programs><United States><United States National Institutes of Health><Universities><Virus-HIV><Wuhan coronavirus><cardiovascular disorder><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019 virus><coronavirus disease-19 virus><developmental><diabetes><hCoV19><human immunodeficiency virus research><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><nCoV2><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><programs><research addressing HIV><research in HIV><research into HIV><research on HIV><research on human immunodeficiency virus><research to address HIV><science on HIV><science to address HIV><studies on HIV><training opportunity>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JEAN BISIMWA NACHEGA

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 22/100

Recent

Active award

$157,225

FY 2026

Project Title

Pitt-Mozambique Training Program (Pitt-MozHRTP) in SARS-CoV-2, Cardiovascular Disease, and Diabetes in People with HIV

Grant Number:

3D43TW011827-05S1

Activity Code:

D43

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/2/2022

End Date:

1/31/2027

Project Abstract

The overall mission of Pitt-MozHRTP is to provide HIV research training opportunities for investigators at Polana Caniço Health Research and Training Center (Centro de Investigação e Treino em Saúde da Polana Caniço, CISPOC) - a key research institution of the Mozambique National Institute of Health...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><AIDS Virus><AIDS focused research><AIDS related research><AIDS research><AIDS science><AIDS specific research><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Area><COVID-19 virus><COVID19 virus><Cardiovascular Diseases><CoV-2><CoV2><Collaborations><Country><Development><Diabetes Mellitus><Doctor of Philosophy><Fellowship><Fostering><Generations><Goals><HIV><HIV focused research><HIV individuals><HIV infected individuals><HIV infected persons><HIV investigation><HIV people><HIV positive individuals><HIV positive people><HIV related research><HIV research><HIV science><HIV specific research><Health><Human Immunodeficiency Viruses><Institution><Investigation on HIV><Investigators><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Master of Science><Master's Degree><Mentors><Mission><Mozambique><NIH><National Institutes of Health><PLWH><PWH><Ph.D.><PhD><Portuguese East Africa><Research><Research Personnel><Researchers><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Site><South Africa><Training><Training Programs><United States><United States National Institutes of Health><Universities><Virus-HIV><Wuhan coronavirus><cardiovascular disorder><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019 virus><coronavirus disease-19 virus><developmental><diabetes><hCoV19><human immunodeficiency virus research><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><nCoV2><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><programs><research addressing HIV><research in HIV><research into HIV><research on HIV><research on human immunodeficiency virus><research to address HIV><science on HIV><science to address HIV><studies on HIV><training opportunity>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Edna Viegas

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 22/100

Recent

Active award

$157,225

FY 2026

Project Title

Pitt-Mozambique Training Program (Pitt-MozHRTP) in SARS-CoV-2, Cardiovascular Disease, and Diabetes in People with HIV

Grant Number:

3D43TW011827-05S1

Activity Code:

D43

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/2/2022

End Date:

1/31/2027

Project Abstract

The overall mission of Pitt-MozHRTP is to provide HIV research training opportunities for investigators at Polana Caniço Health Research and Training Center (Centro de Investigação e Treino em Saúde da Polana Caniço, CISPOC) - a key research institution of the Mozambique National Institute of Health...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><AIDS Virus><AIDS focused research><AIDS related research><AIDS research><AIDS science><AIDS specific research><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Area><COVID-19 virus><COVID19 virus><Cardiovascular Diseases><CoV-2><CoV2><Collaborations><Country><Development><Diabetes Mellitus><Doctor of Philosophy><Fellowship><Fostering><Generations><Goals><HIV><HIV focused research><HIV individuals><HIV infected individuals><HIV infected persons><HIV investigation><HIV people><HIV positive individuals><HIV positive people><HIV related research><HIV research><HIV science><HIV specific research><Health><Human Immunodeficiency Viruses><Institution><Investigation on HIV><Investigators><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Master of Science><Master's Degree><Mentors><Mission><Mozambique><NIH><National Institutes of Health><PLWH><PWH><Ph.D.><PhD><Portuguese East Africa><Research><Research Personnel><Researchers><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Site><South Africa><Training><Training Programs><United States><United States National Institutes of Health><Universities><Virus-HIV><Wuhan coronavirus><cardiovascular disorder><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019 virus><coronavirus disease-19 virus><developmental><diabetes><hCoV19><human immunodeficiency virus research><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><nCoV2><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><programs><research addressing HIV><research in HIV><research into HIV><research on HIV><research on human immunodeficiency virus><research to address HIV><science on HIV><science to address HIV><studies on HIV><training opportunity>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alexi L Vasbinder

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Exploratory lead · 22/100

Recent

Active award

$145,716

FY 2026

Project Title

Epigenetics, accelerated aging, and cardiovascular health during breast cancer treatment

Grant Number:

5R21CA300956-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/17/2025

End Date:

2/28/2027

Project Abstract

PROJECT SUMMARY Although survival from breast cancer (BC) has improved, BC treatment is associated with an increased risk of cardiovascular (CV) complications due in part to the cardiotoxic effects of BC treatment. BC treatments are also linked to reduced exercise capacity and cardiac function, whic...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lee H Harrison

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 22/100

Recent

Active award

$130,333

FY 2026

Project Title

Pitt-Mozambique Training Program (Pitt-MozHRTP) in SARS-CoV-2, Cardiovascular Disease, and Diabetes in People with HIV

Grant Number:

5D43TW011827-05

Activity Code:

D43

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/2/2022

End Date:

1/31/2027

Project Abstract

The overall mission of Pitt-MozHRTP is to provide HIV research training opportunities for investigators at Polana Caniço Health Research and Training Center (Centro de Investigação e Treino em Saúde da Polana Caniço, CISPOC) - a key research institution of the Mozambique National Institute of Health...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><AIDS Virus><AIDS focused research><AIDS related research><AIDS research><AIDS science><AIDS specific research><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Area><COVID-19 virus><COVID19 virus><Cardiovascular Diseases><CoV-2><CoV2><Collaborations><Country><Development><Diabetes Mellitus><Doctor of Philosophy><Fellowship><Fostering><Generations><Goals><HIV><HIV focused research><HIV individuals><HIV infected individuals><HIV infected persons><HIV investigation><HIV people><HIV positive individuals><HIV positive people><HIV related research><HIV research><HIV science><HIV specific research><Health><Human Immunodeficiency Viruses><Institution><Investigation on HIV><Investigators><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Master of Science><Master's Degree><Mentors><Mission><Mozambique><NIH><National Institutes of Health><PLWH><PWH><Ph.D.><PhD><Portuguese East Africa><Research><Research Personnel><Researchers><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Site><South Africa><Training><Training Programs><United States><United States National Institutes of Health><Universities><Virus-HIV><Wuhan coronavirus><cardiovascular disorder><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019 virus><coronavirus disease-19 virus><developmental><diabetes><hCoV19><human immunodeficiency virus research><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><nCoV2><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><programs><research addressing HIV><research in HIV><research into HIV><research on HIV><research on human immunodeficiency virus><research to address HIV><science on HIV><science to address HIV><studies on HIV><training opportunity>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JEAN BISIMWA NACHEGA

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 22/100

Recent

Active award

$130,333

FY 2026

Project Title

Pitt-Mozambique Training Program (Pitt-MozHRTP) in SARS-CoV-2, Cardiovascular Disease, and Diabetes in People with HIV

Grant Number:

5D43TW011827-05

Activity Code:

D43

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/2/2022

End Date:

1/31/2027

Project Abstract

The overall mission of Pitt-MozHRTP is to provide HIV research training opportunities for investigators at Polana Caniço Health Research and Training Center (Centro de Investigação e Treino em Saúde da Polana Caniço, CISPOC) - a key research institution of the Mozambique National Institute of Health...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><AIDS Virus><AIDS focused research><AIDS related research><AIDS research><AIDS science><AIDS specific research><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Area><COVID-19 virus><COVID19 virus><Cardiovascular Diseases><CoV-2><CoV2><Collaborations><Country><Development><Diabetes Mellitus><Doctor of Philosophy><Fellowship><Fostering><Generations><Goals><HIV><HIV focused research><HIV individuals><HIV infected individuals><HIV infected persons><HIV investigation><HIV people><HIV positive individuals><HIV positive people><HIV related research><HIV research><HIV science><HIV specific research><Health><Human Immunodeficiency Viruses><Institution><Investigation on HIV><Investigators><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Master of Science><Master's Degree><Mentors><Mission><Mozambique><NIH><National Institutes of Health><PLWH><PWH><Ph.D.><PhD><Portuguese East Africa><Research><Research Personnel><Researchers><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Site><South Africa><Training><Training Programs><United States><United States National Institutes of Health><Universities><Virus-HIV><Wuhan coronavirus><cardiovascular disorder><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019 virus><coronavirus disease-19 virus><developmental><diabetes><hCoV19><human immunodeficiency virus research><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><nCoV2><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><programs><research addressing HIV><research in HIV><research into HIV><research on HIV><research on human immunodeficiency virus><research to address HIV><science on HIV><science to address HIV><studies on HIV><training opportunity>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Edna Viegas

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 22/100

Recent

Active award

$130,333

FY 2026

Project Title

Pitt-Mozambique Training Program (Pitt-MozHRTP) in SARS-CoV-2, Cardiovascular Disease, and Diabetes in People with HIV

Grant Number:

5D43TW011827-05

Activity Code:

D43

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/2/2022

End Date:

1/31/2027

Project Abstract

The overall mission of Pitt-MozHRTP is to provide HIV research training opportunities for investigators at Polana Caniço Health Research and Training Center (Centro de Investigação e Treino em Saúde da Polana Caniço, CISPOC) - a key research institution of the Mozambique National Institute of Health...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><AIDS Virus><AIDS focused research><AIDS related research><AIDS research><AIDS science><AIDS specific research><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Area><COVID-19 virus><COVID19 virus><Cardiovascular Diseases><CoV-2><CoV2><Collaborations><Country><Development><Diabetes Mellitus><Doctor of Philosophy><Fellowship><Fostering><Generations><Goals><HIV><HIV focused research><HIV individuals><HIV infected individuals><HIV infected persons><HIV investigation><HIV people><HIV positive individuals><HIV positive people><HIV related research><HIV research><HIV science><HIV specific research><Health><Human Immunodeficiency Viruses><Institution><Investigation on HIV><Investigators><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Master of Science><Master's Degree><Mentors><Mission><Mozambique><NIH><National Institutes of Health><PLWH><PWH><Ph.D.><PhD><Portuguese East Africa><Research><Research Personnel><Researchers><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Site><South Africa><Training><Training Programs><United States><United States National Institutes of Health><Universities><Virus-HIV><Wuhan coronavirus><cardiovascular disorder><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019 virus><coronavirus disease-19 virus><developmental><diabetes><hCoV19><human immunodeficiency virus research><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><nCoV2><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><programs><research addressing HIV><research in HIV><research into HIV><research on HIV><research on human immunodeficiency virus><research to address HIV><science on HIV><science to address HIV><studies on HIV><training opportunity>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Odayme Quesada

THE CHRIST HOSPITAL, CINCINNATI, OH

Exploratory lead · 22/100

Recent

Active award

$99,150

FY 2026

Project Title

Identifying Inflammatory and Endothelial Mechanisms promoting Cardiac Deformation in Women with a History of Preeclampsia

Grant Number:

5R03HL177034-02

Activity Code:

R03

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

11/30/2026

Project Abstract

PROJECT SUMMARY Women with a history of preeclampsia (preE) are at a 2-fold higher risk of cardiovascular disease and develop subclinical cardiovascular disease 5 years earlier than women with normotensive pregnancies; however, the mechanism remains unknown. In our K23 study of 150 participants incl...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JASON G UMANS

MEDSTAR HEALTH RESEARCH INSTITUTE, HYATTSVILLE, MD

Exploratory lead · 20/100

Solid budget

Active award

$439,717

FY 2026

Project Title

STRONG HEART STUDY (SHS) - FIELD CENTER, TASK ORDER 001, BASE PERIOD, FEBRUARY 15, 2019 TO FEBRUARY 14, 2020

Grant Number:

75N92019D00030-P00011-759201900074-1

Activity Code:

N01

Mechanism:

R and D Contracts

Agency:

NIH

Start Date:

2/15/2019

End Date:

2/14/2027

Project Abstract

The Strong Heart Study (SHS) is a longitudinal observational study of two combined cohorts followed prospectively: the original SHS cohort recruited in 1989 to 1991 and a Strong Heart Family Study (SHFS) cohort recruited in 1998 to 1999. The original and family cohorts together form the largest, mu...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michelle E Kossack

UNIVERSITY OF CINCINNATI, CINCINNATI, OH

Exploratory lead · 16/100

Active award

$248,999

FY 2026

Project Title

Identifying critical mediators of ovarian and cardiovascular health

Grant Number:

4R00ES036311-03

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2024

End Date:

11/30/2028

Project Abstract

PROJECT SUMMARY/ABSTRACT Environmental contaminant exposure accounts for 20-30% of the known congenital heart disease and is a significant driver of adult heart disease. Likewise, exposure to environmental contamination also adversely affects ovarian health and is thought to be a significant factor...

Research Terms

<2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin><21+ years old><ASCVD><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adventitial Cell><Adverse effects><Advisory Committees><Affect><Age><Apoptosis><Apoptosis Pathway><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Basal Transcription Factor><Basal transcription factor genes><Binding><Biology><Bleeding><Blood><Blood - brain barrier anatomy><Blood Reticuloendothelial System><Blood Vessels><Blood-Brain Barrier><Body System><Brachydanio rerio><Brain Vascular><Cannot achieve a pregnancy><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Malformation><Cardiac Output><Cardiac Toxicity><Cardiac development><Cardiac health><Cardiotoxic><Cardiotoxicity><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Career Counseling><Career Guidance><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Compensation><Coronary Disease><Coronary heart disease><Danio rerio><Data><Development><Difficulty conceiving><Dioxin Compound><Dioxins><Disease><Disorder><Disparities><Disparity><Dysfunction><ECG><EKG><Echocardiogram><Echocardiography><Electrocardiogram><Electrocardiography><Embryo><Embryonic><Environment><Environmental Pollutants><Environmental Pollution><Estrogens><Event><Exposure to><Fecundability><Fecundity><Female><Fertility><Fertilization><Foundations><Functional disorder><Funding><Gene Expression><General Transcription Factor Gene><General Transcription Factors><Generalized Growth><Goals><Growth><Health><Heart><Heart Diseases><Heart Injuries><Heart Malformation><Heart Vascular><Heart failure><Heart health><Hemato-Encephalic Barrier><Hemorrhage><Histology><Histopathology><Human><Hypertension><Impairment><Infertility><Injections><Injury><Institution><Intracellular Communication and Signaling><Investigators><Ligands><Mammalia><Mammals><Mediating><Mediator><Mentors><Modeling><Modern Man><Molecular><Molecular Fingerprinting><Molecular Interaction><Molecular Profiling><Molecular Target><Myocardial depression><Myocardial dysfunction><Nature><Nutrient><O element><O2 element><Occupational Guidance><Oocytes><Organ><Organ System><Ovarian><Ovary><Ovocytes><Oxygen><Pathology><Perfusion><Pericapillary Cell><Pericytes><Perivascular Cell><Permeability><Phenotype><Physiopathology><Play><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Pre-Menopause><Pre-menopausal Period><Premenopausal><Premenopausal Period><Premenopause><Programmed Cell Death><Research><Research Personnel><Researchers><Role><Rouget Cells><Signal Transduction><Signal Transduction Systems><Signaling><Single cell seq><Source><System><TCDD><Tachyarrhythmias><Task Forces><Testing><Tetrachlorodibenzodioxin><Therapeutic Estrogen><Tissue Growth><Toxic effect><Toxicities><Toxicology><Training><Transcription Factor Proto-Oncogene><Transcription factor genes><Transthoracic Echocardiography><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular remodeling><Vocational Counseling><Vocational Guidance><Woman><Work><Zebra Danio><Zebra Fish><Zebrafish><abnormal heart development><adulthood><advisory team><after menopause><aged><ages><angiogenesis><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><biological signal transduction><blood damage><blood loss><bloodbrain barrier><cardiac dysfunction><cardiac failure><cardiac function><cardiac injury><cardiogenesis><cardioprotectant><cardioprotection><cardioprotective><cardiovascular function><cardiovascular health><career><career counselor><cell type><cellular targeting><cerebral vascular><cerebro-vascular><cerebrovascular><childbearing age><circulatory system><comparing females and males><comparing women and men><congenital cardiac abnormality><congenital cardiac anomalies><congenital cardiac disease><congenital cardiac disorder><congenital cardiac malformation><congenital heart abnormality><congenital heart anomaly><congenital heart disease><congenital heart disorder><congenital heart malformation><coronary disorder><design><designing><developmental><effective therapy><effective treatment><environmental chemical><environmental contaminant><environmental contamination><epidemiology research study><epidemiology study><epidemiology survey><executive coaching><females compared to males><females compared with males><females versus males><females vs. males><fertile age><fertility cessation><fertility loss><fertilizations><following menopause><function of the heart><heart development><heart disorder><heart dysfunction><heart formation><heart function><heart output><heart sonography><high blood pressure><human model><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><infertile><injuries><juvenile><juvenile human><male><men><model of human><molecular profile><molecular signature><ontogeny><ovarian damage><ovarian dysfunction><ovarian toxicity><ovotoxicity><ovulatory dysfunction><past menopause><pathophysiology><persistent organic pollutants><post-menopausal><postmenopausal><postmenopausal status><pre-menopausal><premature><prematurity><premenopausal status><programs><reproductive><reproductive age><reproductive development><reproductive years><sex><single cell next generation sequencing><single cell sequencing><skills><social role><tachyrhythmia><toxicant><transcription factor><vascular><vascular bed><vascular contributions><women compared to men><women compared with men><women versus men><women vs. men><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Xu Qin

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 16/100

Active award

$223,754

FY 2026

Project Title

Heterogeneous genetics effects and mediation in Alzheimer's disease

Grant Number:

5R21AG087057-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2026

Project Abstract

Project Summary Down syndrome (DS) is the most common genetic intellectual and developmental disability and has historically been associated with poor life expectancy. However, improvements in medical care have increased the lifespan of individuals with DS to above 60 years. Individuals with DS hav...

Research Terms

<21+ years old><A β-42><A β42><A-beta 42><A-beta42><AD biological marker><AD biomarker><AD dementia><AD pathology><AD pathway><AD related biomarker><AD risk><AD risk factor><AD-associated pathways><AD-related pathways><AD-specific pathways><APOE><Abeta synthesis><Abeta-42><Abeta42><Acceleration><Accounting><Adult><Adult Human><Affect><Alleles><Allelomorphs><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer disease mechanism><Alzheimer pathway><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's Disease Pathway><Alzheimer's amyloid><Alzheimer's biomarker><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease pathology><Alzheimer's disease related biomarker><Alzheimer's disease risk><Alzheimer's mechanism><Alzheimer's pathology><Alzheimer's precursor protein><Alzheimer's related biomarker><Alzheimer's related pathways><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid (Aβ) plaques><Amyloid A4 Protein Precursor><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid Protein Precursor><Amyloid beta-42><Amyloid beta-Protein><Amyloid beta-Protein Precursor><Amyloid beta42><Amyloid β><Amyloid β production><Amyloid β synthesis><Amyloid β-42><Amyloid β-Peptide><Amyloid β-Protein><Amyloid β-Protein Precursor><Amyloid β42><Amyloidβ-42><Amyloidβ42><Apo-E><ApoE protein><Apolipoprotein E><Aβ><Aβ production><Aβ synthesis><Aβ-42><Aβ42><Bayesian Analysis><Bayesian computation><Bayesian inference><Bayesian network analysis><Bayesian spatial analysis><Bayesian statistical analysis><Bayesian statistical inference><Bayesian statistics><Biological><Biological Markers><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Causality><Chromosome 21><Clinical><Clinical Trials><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Communities><Data><Data Set><Dementia><Deposit><Deposition><Disease><Disease Marker><Disease Progression><Disorder><Disturbance in cognition><Down Syndrome><Early Diagnosis><Etiology><Family><Family Characteristics><Family Health><Family Medical History><Family Medical History Epidemiology><Family health status><Family history of><Gene Proteins><Genes><Genetic><Genotype><Goals><Heart Vascular><Heterogeneity><History><Hypothyroidism><Image><Impaired cognition><Increase lifespan><Individual><Individuals with down syndrome><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Intervention><Isoforms><Langdon Down syndrome><Life Expectancy><Link><Machine Learning><Mediating><Mediation><Medical><Medical History><Methodology><Methods><Modeling><Modification><Mongolism><Negotiating><Negotiation><Neuritic Plaques><Pathologic><Pathology><Pathway interactions><Patients><Personal Medical History><Personal Medical History Epidemiology><Population><Primary Senile Degenerative Dementia><Process><Protein Gene Products><Protein Isoforms><Recording of previous events><Research><Role><Sampling><Senile Plaques><Siblings><Sleep Apnea><Sleep Apnea Syndromes><Sleep Hypopnea><Sleep-Disordered Breathing><Source><Statistical Methods><Study models><Testing><Therapeutic Intervention><Training><Trees><Trisomy 21><a beta peptide><abeta><abeta production><adulthood><alzheimer risk><amyloid beta><amyloid beta plaque><amyloid beta production><amyloid beta synthesis><amyloid precursor protein><amyloid-b plaque><amyloid-b protein><autosomal dominant AD><autosomal dominant Alzheimer's disease><aβ plaques><beta amyloid fibril><bio-markers><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><boost longevity><cardiovascular disorder><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><circulatory system><cognitive dysfunction><cognitive loss><computer based prediction><congenital acromicria syndrome><cored plaque><data sharing><demographics><design><designing><develop software><developing computer software><diffuse plaque><disease causation><down syndrome individuals><down syndrome patients><early detection><elongating the lifespan><enhance longevity><extend life span><extend lifespan><extend longevity><flexibility><flexible><foster longevity><histories><imaging><improve lifespan><improve longevity><improved><inclusion criteria><innovate><innovation><innovative><intellectual and developmental disability><intervention therapy><lifespan extension><limited intellectual functioning><machine based learning><mechanisms in AD><mechanisms in Alzheimer's disease><morbus Down><novel><overexpress><overexpression><pathway><pathways associated with AD><pathways associated with Alzheimer's><pathways contribute to Alzheimer's><pathways involved in Alzheimer disease><pathways that contribute to AD><pathways that drive AD><pathways underlying Alzheimer's><patients with down syndrome><people with down syndrome><pre-clinical><preclinical><predictive modeling><primary degenerative dementia><prolong lifespan><prolong longevity><promote lifespan><promote longevity><pseudohypertrophic progressive muscular dystrophy><regression trees><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><senile dementia of the Alzheimer type><sleep-related breathing disorder><social role><software development><soluble amyloid precursor protein><statistic methods><support longevity><symptomatology><targeted agent><trisomy 21 syndrome>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Victor Talisa

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 16/100

Active award

$223,754

FY 2026

Project Title

Heterogeneous genetics effects and mediation in Alzheimer's disease

Grant Number:

5R21AG087057-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2026

Project Abstract

Project Summary Down syndrome (DS) is the most common genetic intellectual and developmental disability and has historically been associated with poor life expectancy. However, improvements in medical care have increased the lifespan of individuals with DS to above 60 years. Individuals with DS hav...

Research Terms

<21+ years old><A β-42><A β42><A-beta 42><A-beta42><AD biological marker><AD biomarker><AD dementia><AD pathology><AD pathway><AD related biomarker><AD risk><AD risk factor><AD-associated pathways><AD-related pathways><AD-specific pathways><APOE><Abeta synthesis><Abeta-42><Abeta42><Acceleration><Accounting><Adult><Adult Human><Affect><Alleles><Allelomorphs><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer disease mechanism><Alzheimer pathway><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's Disease Pathway><Alzheimer's amyloid><Alzheimer's biomarker><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease pathology><Alzheimer's disease related biomarker><Alzheimer's disease risk><Alzheimer's mechanism><Alzheimer's pathology><Alzheimer's precursor protein><Alzheimer's related biomarker><Alzheimer's related pathways><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid (Aβ) plaques><Amyloid A4 Protein Precursor><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid Protein Precursor><Amyloid beta-42><Amyloid beta-Protein><Amyloid beta-Protein Precursor><Amyloid beta42><Amyloid β><Amyloid β production><Amyloid β synthesis><Amyloid β-42><Amyloid β-Peptide><Amyloid β-Protein><Amyloid β-Protein Precursor><Amyloid β42><Amyloidβ-42><Amyloidβ42><Apo-E><ApoE protein><Apolipoprotein E><Aβ><Aβ production><Aβ synthesis><Aβ-42><Aβ42><Bayesian Analysis><Bayesian computation><Bayesian inference><Bayesian network analysis><Bayesian spatial analysis><Bayesian statistical analysis><Bayesian statistical inference><Bayesian statistics><Biological><Biological Markers><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Causality><Chromosome 21><Clinical><Clinical Trials><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Communities><Data><Data Set><Dementia><Deposit><Deposition><Disease><Disease Marker><Disease Progression><Disorder><Disturbance in cognition><Down Syndrome><Early Diagnosis><Etiology><Family><Family Characteristics><Family Health><Family Medical History><Family Medical History Epidemiology><Family health status><Family history of><Gene Proteins><Genes><Genetic><Genotype><Goals><Heart Vascular><Heterogeneity><History><Hypothyroidism><Image><Impaired cognition><Increase lifespan><Individual><Individuals with down syndrome><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Intervention><Isoforms><Langdon Down syndrome><Life Expectancy><Link><Machine Learning><Mediating><Mediation><Medical><Medical History><Methodology><Methods><Modeling><Modification><Mongolism><Negotiating><Negotiation><Neuritic Plaques><Pathologic><Pathology><Pathway interactions><Patients><Personal Medical History><Personal Medical History Epidemiology><Population><Primary Senile Degenerative Dementia><Process><Protein Gene Products><Protein Isoforms><Recording of previous events><Research><Role><Sampling><Senile Plaques><Siblings><Sleep Apnea><Sleep Apnea Syndromes><Sleep Hypopnea><Sleep-Disordered Breathing><Source><Statistical Methods><Study models><Testing><Therapeutic Intervention><Training><Trees><Trisomy 21><a beta peptide><abeta><abeta production><adulthood><alzheimer risk><amyloid beta><amyloid beta plaque><amyloid beta production><amyloid beta synthesis><amyloid precursor protein><amyloid-b plaque><amyloid-b protein><autosomal dominant AD><autosomal dominant Alzheimer's disease><aβ plaques><beta amyloid fibril><bio-markers><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><boost longevity><cardiovascular disorder><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><circulatory system><cognitive dysfunction><cognitive loss><computer based prediction><congenital acromicria syndrome><cored plaque><data sharing><demographics><design><designing><develop software><developing computer software><diffuse plaque><disease causation><down syndrome individuals><down syndrome patients><early detection><elongating the lifespan><enhance longevity><extend life span><extend lifespan><extend longevity><flexibility><flexible><foster longevity><histories><imaging><improve lifespan><improve longevity><improved><inclusion criteria><innovate><innovation><innovative><intellectual and developmental disability><intervention therapy><lifespan extension><limited intellectual functioning><machine based learning><mechanisms in AD><mechanisms in Alzheimer's disease><morbus Down><novel><overexpress><overexpression><pathway><pathways associated with AD><pathways associated with Alzheimer's><pathways contribute to Alzheimer's><pathways involved in Alzheimer disease><pathways that contribute to AD><pathways that drive AD><pathways underlying Alzheimer's><patients with down syndrome><people with down syndrome><pre-clinical><preclinical><predictive modeling><primary degenerative dementia><prolong lifespan><prolong longevity><promote lifespan><promote longevity><pseudohypertrophic progressive muscular dystrophy><regression trees><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><senile dementia of the Alzheimer type><sleep-related breathing disorder><social role><software development><soluble amyloid precursor protein><statistic methods><support longevity><symptomatology><targeted agent><trisomy 21 syndrome>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jiebiao Wang

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 16/100

Active award

$223,754

FY 2026

Project Title

Heterogeneous genetics effects and mediation in Alzheimer's disease

Grant Number:

5R21AG087057-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2026

Project Abstract

Project Summary Down syndrome (DS) is the most common genetic intellectual and developmental disability and has historically been associated with poor life expectancy. However, improvements in medical care have increased the lifespan of individuals with DS to above 60 years. Individuals with DS hav...

Research Terms

<21+ years old><A β-42><A β42><A-beta 42><A-beta42><AD biological marker><AD biomarker><AD dementia><AD pathology><AD pathway><AD related biomarker><AD risk><AD risk factor><AD-associated pathways><AD-related pathways><AD-specific pathways><APOE><Abeta synthesis><Abeta-42><Abeta42><Acceleration><Accounting><Adult><Adult Human><Affect><Alleles><Allelomorphs><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer disease mechanism><Alzheimer pathway><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's Disease Pathway><Alzheimer's amyloid><Alzheimer's biomarker><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease pathology><Alzheimer's disease related biomarker><Alzheimer's disease risk><Alzheimer's mechanism><Alzheimer's pathology><Alzheimer's precursor protein><Alzheimer's related biomarker><Alzheimer's related pathways><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid (Aβ) plaques><Amyloid A4 Protein Precursor><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid Protein Precursor><Amyloid beta-42><Amyloid beta-Protein><Amyloid beta-Protein Precursor><Amyloid beta42><Amyloid β><Amyloid β production><Amyloid β synthesis><Amyloid β-42><Amyloid β-Peptide><Amyloid β-Protein><Amyloid β-Protein Precursor><Amyloid β42><Amyloidβ-42><Amyloidβ42><Apo-E><ApoE protein><Apolipoprotein E><Aβ><Aβ production><Aβ synthesis><Aβ-42><Aβ42><Bayesian Analysis><Bayesian computation><Bayesian inference><Bayesian network analysis><Bayesian spatial analysis><Bayesian statistical analysis><Bayesian statistical inference><Bayesian statistics><Biological><Biological Markers><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Causality><Chromosome 21><Clinical><Clinical Trials><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Communities><Data><Data Set><Dementia><Deposit><Deposition><Disease><Disease Marker><Disease Progression><Disorder><Disturbance in cognition><Down Syndrome><Early Diagnosis><Etiology><Family><Family Characteristics><Family Health><Family Medical History><Family Medical History Epidemiology><Family health status><Family history of><Gene Proteins><Genes><Genetic><Genotype><Goals><Heart Vascular><Heterogeneity><History><Hypothyroidism><Image><Impaired cognition><Increase lifespan><Individual><Individuals with down syndrome><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Intervention><Isoforms><Langdon Down syndrome><Life Expectancy><Link><Machine Learning><Mediating><Mediation><Medical><Medical History><Methodology><Methods><Modeling><Modification><Mongolism><Negotiating><Negotiation><Neuritic Plaques><Pathologic><Pathology><Pathway interactions><Patients><Personal Medical History><Personal Medical History Epidemiology><Population><Primary Senile Degenerative Dementia><Process><Protein Gene Products><Protein Isoforms><Recording of previous events><Research><Role><Sampling><Senile Plaques><Siblings><Sleep Apnea><Sleep Apnea Syndromes><Sleep Hypopnea><Sleep-Disordered Breathing><Source><Statistical Methods><Study models><Testing><Therapeutic Intervention><Training><Trees><Trisomy 21><a beta peptide><abeta><abeta production><adulthood><alzheimer risk><amyloid beta><amyloid beta plaque><amyloid beta production><amyloid beta synthesis><amyloid precursor protein><amyloid-b plaque><amyloid-b protein><autosomal dominant AD><autosomal dominant Alzheimer's disease><aβ plaques><beta amyloid fibril><bio-markers><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><boost longevity><cardiovascular disorder><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><circulatory system><cognitive dysfunction><cognitive loss><computer based prediction><congenital acromicria syndrome><cored plaque><data sharing><demographics><design><designing><develop software><developing computer software><diffuse plaque><disease causation><down syndrome individuals><down syndrome patients><early detection><elongating the lifespan><enhance longevity><extend life span><extend lifespan><extend longevity><flexibility><flexible><foster longevity><histories><imaging><improve lifespan><improve longevity><improved><inclusion criteria><innovate><innovation><innovative><intellectual and developmental disability><intervention therapy><lifespan extension><limited intellectual functioning><machine based learning><mechanisms in AD><mechanisms in Alzheimer's disease><morbus Down><novel><overexpress><overexpression><pathway><pathways associated with AD><pathways associated with Alzheimer's><pathways contribute to Alzheimer's><pathways involved in Alzheimer disease><pathways that contribute to AD><pathways that drive AD><pathways underlying Alzheimer's><patients with down syndrome><people with down syndrome><pre-clinical><preclinical><predictive modeling><primary degenerative dementia><prolong lifespan><prolong longevity><promote lifespan><promote longevity><pseudohypertrophic progressive muscular dystrophy><regression trees><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><senile dementia of the Alzheimer type><sleep-related breathing disorder><social role><software development><soluble amyloid precursor protein><statistic methods><support longevity><symptomatology><targeted agent><trisomy 21 syndrome>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MANUELA BARTOLI

AUGUSTA UNIVERSITY, AUGUSTA, GA

Exploratory lead · 16/100

Active award

$192,500

FY 2026

Project Title

Chronic HIV infection and ischemic retinopathies

Grant Number:

5R21EY037078-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2025

End Date:

1/31/2027

Project Abstract

PROJECT SUMMARY The overall goal of this novel exploratory proposal is to investigate/assess the potential impact of chronic HIV infection and /or anti-HIV drugs on the development and progression of ischemic retinopathies. Combinatorial- antiviral therapies (cART) have increased the life-expectancy...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HELAINE E. RESNICK

MISSOURI BREAKS RESEARCH, INC., EAGLE BUTTE, SD

Exploratory lead · 16/100

Active award

$154,846

FY 2026

Project Title

STRONG HEART STUDY (SHS) - MISSOURI BREAKS INDUSTRIES RESEARCH, INC., FIELD CENTER (FC), TASK AREA C: DATA BOOK

Grant Number:

75N92019D00029-0-759202600001-1

Activity Code:

N01

Mechanism:

R and D Contracts

Agency:

NIH

Start Date:

1/12/2026

End Date:

2/14/2027

Project Abstract

The Strong Heart Study (SHS) is a longitudinal observational study of two combined cohorts followed prospectively: the original SHS cohort recruited in 1989 to 1991 and a Strong Heart Family Study (SHFS) cohort recruited in 1998 to 1999. The original and family cohorts together form the largest, mul...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Juliet Gopinath

UNIVERSITY OF COLORADO, Boulder, CO

Exploratory lead · 16/100

Active award

$148,319

FY 2026

Project Title

Low-voltage liquid lens enabled endoscopic optical coherence tomography

Grant Number:

5R21EB037238-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/10/2025

End Date:

12/31/2027

Project Abstract

Project Summary This is an application in response to FOA number, PAR-24-022 (NIBIB), “Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)”. Recently, we demonstrated non-mechanical scanning for imaging. This technology can be used for a miniature forward-viewing en...

Research Terms

<3-D Imaging><3-D print><3-D printer><3D Print><3D imaging><3D printer><3D printing><Award><Biopsy><Cancers><Cardiology><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Clinical Trials><Compensation><Computer software><Coupled><Custom><Device Designs><Devices><Diameter><Dimensions><Doppler OCT><Electrostatics><Elements><Endoscopes><Engineering><Fiber><Fibrosis><Geometry><Goals><Heart Vascular><Human><Image><Imaging Procedures><Imaging Technics><Imaging Techniques><Investigators><Laser Electromagnetic><Laser Radiation><Lasers><Lateral><Length><Letters><Light><Liquid substance><Malignant Neoplasms><Malignant Tumor><Mechanics><Meniscus><Meniscus structure of joint><Methods><Microscopy><Miniaturisations><Miniaturization><Modeling><Modern Man><Monitor><NIBIB><National Institute of Biomedical Imaging and Bioengineering><Nature><Nervous System Diseases><Nervous System Disorder><Neurologic Disorders><Neurological Disorders><OCT Tomography><Operative Procedures><Operative Surgical Procedures><Optical Coherence Tomography><Optics><Performance><Photoradiation><Price><RF ablation><Radio Frequency Ablation><Radiofrequency Ablation><Radiofrequency Interstitial Ablation><Research><Research Personnel><Researchers><Resistance><Resolution><Sampling><Scanning><Shapes><Software><Source><Speed><Surgical><Surgical Interventions><Surgical Procedure><System><Technology><Testing><Thick><Thickness><Three-Dimensional Imaging><Tissue Sample><Tissue imaging><Variant><Variation><Weight><Work><adaptive optics><cardiac imaging><cardiac scanning><cardiovascular disorder><cardiovascular imaging><circulatory system><clinical diagnostics><customs><design><designing><electric field><fluid><heart imaging><heart scanning><high resolution imaging><imaging><imaging in vivo><improved><in vivo><in vivo imaging><innovate><innovation><innovative><insight><lens><lenses><light weight><lightweight><liquid><malignancy><mechanic><mechanical><medical diagnostic><meter><miniaturize><miniaturized><neoplasm/cancer><neurological disease><novel><operation><operations><optical><optical Doppler tomography><optical coherence Doppler tomography><point of care><power consumption><pricing><prototype><resistant><resolutions><response><surgery><three dimensional printing><tissue phantom><voltage><weights>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DEDRA S BUCHWALD

MEDSTAR HEALTH RESEARCH INSTITUTE, HYATTSVILLE, MD

Exploratory lead · 16/100

Active award

$129,024

FY 2026

Project Title

STRONG HEART STUDY (SHS) - MEDSTAR HEALTH RESEARCH INSTITUTE, INC., FIELD CENTER (FC), TASK AREA C: DATA BOOK

Grant Number:

75N92019D00030-0-759202600001-1

Activity Code:

N01

Mechanism:

R and D Contracts

Agency:

NIH

Start Date:

1/12/2026

End Date:

2/14/2027

Project Abstract

The Strong Heart Study (SHS) is a longitudinal observational study of two combined cohorts followed prospectively: the original SHS cohort recruited in 1989 to 1991 and a Strong Heart Family Study (SHFS) cohort recruited in 1998 to 1999. The original and family cohorts together form the largest, mul...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alana Teresa Brennan

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Exploratory lead · 16/100

Active award

$81,750

FY 2026

Project Title

Assessing the mediating role of kidney function and weight/BMI in the association between INSTI use and blood pressure changes and hypertension in PWH: a secondary analysis of the REPRIEVE study.

Grant Number:

5R03AI189203-02

Activity Code:

R03

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2026

Project Abstract

Project Summary Our R03 application critically evaluates cardiovascular risks associated with integrase strand transfer inhibitors (INSTIs), focusing on blood pressure and hypertension among people living with HIV. Utilizing data from the REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV)...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

TERRY L. SHEPPARD

KEYSTONE SYMPOSIA, SILVERTHORNE, CO

Exploratory lead · 16/100

Active award

$18,100

FY 2026

Project Title

Cardiometabolism in Health and Disease

Grant Number:

1R13HL184864-01

Activity Code:

R13

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/21/2026

End Date:

12/31/2026

Project Abstract

Abstract Support is requested for a Keystone Symposia conference entitled “Cardiometabolism in Health and Disease,” organized by Drs. Daniel P. Kelly, Rong Tian and William C. Sessa, with scientific programming input from Keystone Symposia. The meeting will take place January 26–29, 2026 at the Keys...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sanket S Dhruva

VETERANS AFFAIRS MED CTR SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Improving Safety of Cardiovascular Implantable Electronic Devices in Veterans

Grant Number:

5IK2HX003357-04

Activity Code:

IK2

Mechanism:

Other

Agency:

VA

Start Date:

2/1/2022

End Date:

1/31/2027

Project Abstract

Background: This proposal is intended to support the career development of Sanket Dhruva, MD, MHS, a Staff Cardiologist at the San Francisco VA and Assistant Professor of Medicine at the University of California, San Francisco into an independent VA health services researcher with the training and e...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

YAN-TING E. SHIU

VA SALT LAKE CITY HEALTHCARE SYSTEM, SALT LAKE CITY, UT

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

BCCMA: Cardiovascular Remodeling following Arteriovenous Fistula Creation: Aging Contributes to Adverse Arteriovenous Fistula Remodeling

Grant Number:

5I01BX006078-02

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

12/1/2024

End Date:

11/30/2028

Project Abstract

Arteriovenous fistulas (AVFs) are the preferred vascular access for hemodialysis patients with end stage kidney disease (ESKD). A large proportion of AVFs (30-60%) created in the United States fail to successfully mature (i.e., lack sufficiently large lumen and blood flow) and require assisted matur...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Russell S. Richardson

VA SALT LAKE CITY HEALTHCARE SYSTEM, SALT LAKE CITY, UT

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Passive leg movement: A tool to assess vascular health and guide rehabilitation

Grant Number:

5I01RX003207-06

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

10/1/2020

End Date:

9/30/2026

Project Abstract

Current U.S. Veteran demographics reveal an aging population with significant cardiovascular dysfunction. This ultimately manifests as mobility limitation, inactivity, and a subsequent worsening of cardiovascular disease (CVD) that often leads to death. However, despite this clear negative cycle of ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gino S Panza

JOHN D DINGELL VA MEDICAL CENTER, DETROIT, MI

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals with Spinal Cord Injuries

Grant Number:

5IK2RX003847-04

Activity Code:

IK2

Mechanism:

Other

Agency:

VA

Start Date:

11/1/2022

End Date:

10/31/2026

Project Abstract

Individuals with a spinal cord injury (SCI) above the 6th thoracic vertebrae experience severe autonomic dysfunction. These individuals lose the ability to control blood pressure (BP) during a noxious or non-noxious stimulus below the injury (Autonomic Dysreflexia [AD]) and during positional changes...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Darshan Prahlad Patel

VA SAN DIEGO HEALTHCARE SYSTEM, SAN DIEGO, CA

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

Polygenic Risk Stratification for Cardiovascular Disease in Young Male Veterans presenting with Erectile Dysfunction

Grant Number:

5IK2BX006522-02

Activity Code:

IK2

Mechanism:

Other

Agency:

VA

Start Date:

10/1/2024

End Date:

9/30/2029

Project Abstract

SUMMARY Erectile dysfunction (ED) affects up to 62% of Veterans and represents a common, yet underappreciated component of multi-morbidity. In addition to the negative impact of ED on quality of life, ED is also an independent risk factor for cardiovascular disease and can represent a precipitating ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Susan Kathleen Wood

VETERANS HEALTH ADMINISTRATION, COLUMBIA, SC

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

Neural regulation of susceptibility to hyperarousal

Grant Number:

5I01BX005661-04

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

10/1/2022

End Date:

9/30/2026

Project Abstract

Since 2001 nearly 2 million US troops have served in the wars in Afghanistan or Iraq. Common to these hostile environments, exposure to a traumatic stress can lead to post traumatic stress disorder (PTSD). As a result, up to 31% of soldiers suffer from PTSD at some point in their lives. In addition ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yabing Chen

PORTLAND VA MEDICAL CENTER, PORTLAND, OR

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

BLRD Research Career Scientist Award Renewal

Grant Number:

5IK6BX005800-06

Activity Code:

IK6

Mechanism:

Other

Agency:

VA

Start Date:

10/1/2021

End Date:

9/30/2028

Project Abstract

Project Summary/Abstract My major research focus is to understand the fundamental mechanisms of gene regulation and function in the development of cardiovascular disease, a major health burden for our veterans. Our overarching goals are to translate the findings into identification of novel molecula...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Principal Investigator Finder

Search Principal Investigators

Search Results

Opportunity Digest

Matthias Nahrendorf

Project Title

Project Abstract

Research Terms

Jennifer S Pollock

Project Title

Project Abstract

Research Terms

JAY D. HORTON

Project Title

Project Abstract

Research Terms

Kiran Musunuru

Project Title

Project Abstract

Research Terms

Daniel James Rader

Project Title

Project Abstract

Research Terms

Nicholas James Leeper

Project Title

Project Abstract

Research Terms

Amit Jasvant Shah

Project Title

Project Abstract

Research Terms

Viola Vaccarino

Project Title

Project Abstract

Research Terms

Douglas E Vaughan

Project Title

Project Abstract

Research Terms

Eric D Lazartigues

Project Title

Project Abstract

Research Terms

Changcheng Zhou

Project Title

Project Abstract

Research Terms

Steven D Crowley

Project Title

Project Abstract

Research Terms

L Elliot Elliot Hong

Project Title

Project Abstract

Research Terms

Safiya Richardson

Project Title

Project Abstract

Research Terms

KATHRYN J MOORE

Project Title

Project Abstract

Research Terms

JULIO ALONSO CHIRINOS MEDINA

Project Title

Project Abstract

Research Terms

Jordana B. Cohen

Project Title

Project Abstract

Research Terms

Fritz J Sedlazeck

Project Title

Project Abstract

Research Terms

Girish Nitin Nadkarni

Project Title

Project Abstract

Research Terms