NIH Grant Search by PI — Funded Principal Investigator Finder

Search NIH grants by PI name or research area. Look up funded principal investigators, see their NIH RePORTER awards, institutions, and project details.

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Enter a research topic, disease, or technology to find principal investigators with NIH funding in that area. To look up a specific PI by name, use the PI Funding Status check.

Search Results

Found 367 principal investigators from 200 displayed projects for "U01" (2021–2026)

Note: 1,393 projects matched but only the first 200 were analyzed. Try narrowing your search with a more specific term or selecting "Project title only".

Opportunity Digest

Heuristic scoring to help trainees and job seekers prioritize which labs to inspect first.

41

High-opportunity leads

285

Likely hiring signals

11

Training-friendly awards

55

Average opportunity score

Prioritize records with strong opportunity signals, then validate fit using abstracts, institution pages, and lab websites.

Filter for opportunity type

Michelle Lynn Sever

PPD DEVELOPMENT LP, WILMINGTON, NC

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$8,961,979
FY 2026

Project Title

PPDs Application for the Transplantation Statistical and Clinical Coordinating Center (T-SCCC) (U01 Clinical Trial Not Allowed)

Grant Number:

5U01AI178756-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/12/2023

End Date:

4/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract To support DAIT's efforts to increase understanding of the causes and mechanisms that lead to the development of immunologic diseases and to expand knowledge that can be applied to improving techniques of diagnosis, treatment, and prevention, the T-SCCC will provide experien...

Research Terms

<Address><Adverse Experience><Adverse event><Area><Assay><Bioassay><Biological Assay><Biological Markers><Biometrics><Biometry><Biostatistics><Client><Clinical><Clinical Data><Clinical Investigator><Clinical Protocols><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Data Monitoring Committees><Collaborations><Collection><Communication><Complex><Data><Data Bases><Data Collection><Data Monitoring Committees><Data Reporting><Data Security><Data Set><Data and Safety Monitoring Boards><Data awareness><Databases><Decentralization><Dedications><Development><Development Plans><Diagnosis><Enrollment><Ensure><Environment><Epidemiology><Ethics><Funding><GCP standard><Genetic study><Good Clinical Practice><Government Programs><Guidelines><Health><Home><Human Resources><Hybrids><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune Tolerance><Immune response><Immunologic Diseases><Immunologic Tolerance><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Infrastructure><Internet><Investigators><Journals><Knowledge><Label><Leadership><Longitudinal observational study><Magazine><Maintenance><Manpower><Manuscripts><Methodology><Methods><Monitor><Morbidity><NIAID><National Institute of Allergy and Infectious Disease><On-Line Systems><Online Systems><Participant><Patients><Peer Review><Performance><Position><Positioning Attribute><Prevention><Procedures><Process><Protocol><Protocols documentation><Public Health><Publications><Quality Control><Regulation><Reporting><Reproducibility><Research><Research Design><Research Personnel><Research Resources><Researchers><Resources><Safety><Safety Monitoring Boards><Sample Size><Science><Scientific Publication><Scientist><Secure><Security><Serious Adverse Event><Services><Severe Adverse Event><Shipping><Site><Standardization><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Structure><Study Type><System><Techniques><Technology><Time><Training><Transplantation><Visit><Visualization><WWW><Work><access restrictions><allotransplant><allotransplantation><authority><bio-markers><biologic marker><biomarker><data base><data integrity><data management><data portal><data quality><data quality/integrity><data representation><data representations><data sharing><data sharing portal><data standardization><data standards><database design><design><designing><developmental><digital><empowerment><enroll><epidemiologic><epidemiological><ethical><experience><flexibility><flexible><homes><host response><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immune system tolerance><immune unresponsiveness><immunological paralysis><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><information security><innovate><innovation><innovative><long term observational study><online computer><participant safety><personnel><pharmacologic><procedure safety><programs><protocol development><quality assurance><recruit><safe procedure><sample collection><serious adverse experience><serious adverse reaction><service programs><specimen collection><statistical analysis><study design><subject safety><success><televisit><time use><transplant><web><web based><world wide web>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael Anthony Moody

DUKE UNIVERSITY, DURHAM, NC

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$2,242,760
FY 2026

Project Title

A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidum

Grant Number:

5U01AI182179-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/22/2024

End Date:

3/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Abstract - A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidum The scientific premise of this CRC proposal rests upon our three decades of work defining the molecular architecture of the outer membrane (OM) of Treponema pallidum subsp. pallidum (TPA), coupled wi...

Research Terms

<Animal Model><Animal Models and Related Studies><Animals><Antibodies><Antigenic Determinants><Antigens><Architecture><Assay><Award><Binding Determinants><Bioassay><Bioinformatics><Biological Assay><Clinical Treatment Moab><Connecticut><Contracting Opportunities><Contracts><Coupled><Development><Disease><Disorder><Domestic Rabbit><E coli><E. coli><Early-Stage Clinical Trials><Engineering><Engineering / Architecture><Ensure><Epitopes><Escherichia coli><Extracellular Protein><Generalized Growth><Good Manufacturing Process><Good manufacturing practice><Grant><Growth><Health><Human><IND Filing><IND application><IND package><IND submission><Immune response><Immunity><Immunization><In Vitro><Individual><Investigation><Investigational New Drug Application><Knowledge><Laboratories><Laboratory Research><Membrane><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Messenger RNA><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Molecular Configuration><Molecular Conformation><Molecular Stereochemistry><Monoclonal Antibodies><Murine><Mus><Order Spirochaetales><Oryctolagus cuniculus><Pennsylvania><Perinatal Mortalities><Perinatal lethality><Perinatal mortality demographics><Phase 1 Clinical Trials><Phase I Clinical Trials><Preclinical data><Process><Production><Quality Control><Rabbits><Rabbits Mammals><Reagent><Reporting><Research><Rest><Spirochaetales><Spirochetes><Surface><Surface Proteins><Syphilis><T pallidum><T. pallidum><Testing><Tissue Growth><Toxicology><Treponema pallidum><Treponema pallidum subsp. pallidum><Treponema pallidum subspecies pallidum><United States><Vaccine Production><Vaccines><Variant><Variation><Vertical Disease Transmission><Virus-like particle><Work><adverse birth outcomes><base><bases><biophysical approaches><biophysical methodology><biophysical methods><biophysical techniques><conformation><conformational><conformational state><conformationally><conformations><design><designing><develop a vaccine><develop vaccines><development of a vaccine><developmental><experiment><experimental research><experimental study><experiments><extracellular><genomic data><genomic dataset><great pox><head-to-head analysis><head-to-head comparison><host response><immune system response><immunogen><immunogenic><immunoresponse><lipid based nanoparticle><lipid nanoparticle><mAbs><mRNA><manufacture><manufacturing organization><meeting><meetings><membrane structure><model of animal><monoclonal Abs><mother to child transmission><ontogeny><perinatal deaths><phase 1 trial><phase I protocol><phase I trial><physical property><pre-clinical><preclinical><preclinical findings><preclinical information><produce vaccines><programs><response><scaffold><scaffolding><success><syphilis vaccine><vaccine development><vaccine platform><vaccinology><virus-like nanoparticles><viruslike particle>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Justin D Radolf

DUKE UNIVERSITY, DURHAM, NC

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$2,242,760
FY 2026

Project Title

A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidum

Grant Number:

5U01AI182179-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/22/2024

End Date:

3/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Abstract - A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidum The scientific premise of this CRC proposal rests upon our three decades of work defining the molecular architecture of the outer membrane (OM) of Treponema pallidum subsp. pallidum (TPA), coupled wi...

Research Terms

<Animal Model><Animal Models and Related Studies><Animals><Antibodies><Antigenic Determinants><Antigens><Architecture><Assay><Award><Binding Determinants><Bioassay><Bioinformatics><Biological Assay><Clinical Treatment Moab><Connecticut><Contracting Opportunities><Contracts><Coupled><Development><Disease><Disorder><Domestic Rabbit><E coli><E. coli><Early-Stage Clinical Trials><Engineering><Engineering / Architecture><Ensure><Epitopes><Escherichia coli><Extracellular Protein><Generalized Growth><Good Manufacturing Process><Good manufacturing practice><Grant><Growth><Health><Human><IND Filing><IND application><IND package><IND submission><Immune response><Immunity><Immunization><In Vitro><Individual><Investigation><Investigational New Drug Application><Knowledge><Laboratories><Laboratory Research><Membrane><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Messenger RNA><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Molecular Configuration><Molecular Conformation><Molecular Stereochemistry><Monoclonal Antibodies><Murine><Mus><Order Spirochaetales><Oryctolagus cuniculus><Pennsylvania><Perinatal Mortalities><Perinatal lethality><Perinatal mortality demographics><Phase 1 Clinical Trials><Phase I Clinical Trials><Preclinical data><Process><Production><Quality Control><Rabbits><Rabbits Mammals><Reagent><Reporting><Research><Rest><Spirochaetales><Spirochetes><Surface><Surface Proteins><Syphilis><T pallidum><T. pallidum><Testing><Tissue Growth><Toxicology><Treponema pallidum><Treponema pallidum subsp. pallidum><Treponema pallidum subspecies pallidum><United States><Vaccine Production><Vaccines><Variant><Variation><Vertical Disease Transmission><Virus-like particle><Work><adverse birth outcomes><base><bases><biophysical approaches><biophysical methodology><biophysical methods><biophysical techniques><conformation><conformational><conformational state><conformationally><conformations><design><designing><develop a vaccine><develop vaccines><development of a vaccine><developmental><experiment><experimental research><experimental study><experiments><extracellular><genomic data><genomic dataset><great pox><head-to-head analysis><head-to-head comparison><host response><immune system response><immunogen><immunogenic><immunoresponse><lipid based nanoparticle><lipid nanoparticle><mAbs><mRNA><manufacture><manufacturing organization><meeting><meetings><membrane structure><model of animal><monoclonal Abs><mother to child transmission><ontogeny><perinatal deaths><phase 1 trial><phase I protocol><phase I trial><physical property><pre-clinical><preclinical><preclinical findings><preclinical information><produce vaccines><programs><response><scaffold><scaffolding><success><syphilis vaccine><vaccine development><vaccine platform><vaccinology><virus-like nanoparticles><viruslike particle>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Theodore M Kamenecka

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,781,729
FY 2026

Project Title

Preclinical development of a precision therapy for a monogenic mental health disorder

Grant Number:

5U01MH136567-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/16/2024

End Date:

1/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY In this project, we propose to develop primary and secondary lead small molecules into preclinical drug candidates for a precision SYNGAP1-DEE therapy. This research is consistent with the mission of NIMH because this genetic disorder impacts mental health and behavior through impair...

Research Terms

<ASD><Adverse effects><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Automation><Automobile Driving><Behavior><Behavioral><Biological Agent><Biological Products><Biology><Brain><Brain Nervous System><CNS Nervous System><Care Givers><Caregivers><Central Nervous System><Chemical Agents><Chemical Structure><Chemicals><Clinical Research><Clinical Study><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><DNA mutation><Development><Diagnosis><Disease><Disorder><Distress><Disturbance in cognition><Dose><Drug Kinetics><Drugs><Early Infantile Autism><Encephalon><Ensure><Epilepsy><Epileptic Seizures><Epileptics><Escalante syndrome><Exhibits><Family><Formulation><Fragile X><Fragile X Syndrome><Funding><Gene Expression><Gene Targeting><Genes><Genetic><Genetic Change><Genetic Diseases><Genetic defect><Genetic mutation><Goals><Human><Impaired cognition><Impairment><In Vitro><Infantile Autism><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Kanner's Syndrome><Knowledge><Lead><Link><Live Birth><Martin-Bell Syndrome><Martin-Bell-Renpenning syndrome><Medication><Medicinal Chemistry><Mental Health><Mental Hygiene><Mental disorders><Mental health disorders><Mice><Mice Mammals><Microsomes><Mission><Modern Man><Murine><Mus><Mutation><NIMH><National Institute of Mental Health><Nerve Cells><Nerve Unit><Nervous System Physiology><Neural Cell><Neuraxis><Neurocyte><Neurodevelopmental Disorder><Neurologic function><Neurological Development Disorder><Neurological function><Neurons><Oral><Outcome><PK/PD><Pathogenicity><Pathway interactions><Patients><Pb element><Penetrance><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Pharmaceutical Preparations><Pharmacokinetics><Pharmacology><Phenotype><Pre-clinical Drug Testing/Development><Precision therapeutics><Preclinical Drug Development><Preclinical Drug Testing/Development><Prevalence><Property><Proteins><Psychiatric Disease><Psychiatric Disorder><Psychological Health><QOL improvement><R-Series Research Projects><R01 Mechanism><R01 Program><Renpenning syndrome 2><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Risk><SYNGAP1><Safety><Seizure Disorder><Seizures><Solubility><Spinal Column><Spine><Synaptic Ras GTPase Activating Protein 1><Technology><Testing><Variant><Variation><Vertebral column><Work><X-linked mental deficiency-megalotestes syndrome><X-linked mental retardation with fragile X syndrome><X-linked mental retardation-fragile site 1 syndrome><autism spectral disorder><autism spectrum disorder><autism-fragile X (AFRAX) syndrome><autistic spectrum disorder><backbone><biologics><biopharmaceutical><biotherapeutic agent><brain cell><brain tissue><chemical library><cognitive dysfunction><cognitive enhancement><cognitive loss><design><designing><determine efficacy><developmental><driving><drug candidate><drug/agent><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><epilepsia><epileptogenic><evaluate efficacy><examine efficacy><fra(X) syndrome><fra(X)(28) syndrome><fra(X)(q27) syndrome><fra(X)(q27-28) syndrome><fragile X-mental retardation syndrome><fragile Xq syndrome><fragile site mental retardation 1><genetic approach><genetic condition><genetic disorder><genetic strategy><genome mutation><heavy metal Pb><heavy metal lead><improved><improvements in QOL><improvements in quality of life><in vivo><individual patient><intellectual and developmental disability><lead optimization><lead series><limited intellectual functioning><macro-orchidism-marker X (MOMX) syndrome><macro-orchidism-marker X syndrome><mar(X) syndrome><marker X syndrome><mental illness><mental retardation-macroorchidism syndrome><model of animal><mouse genetics><nervous system function><neurodevelopmental disease><neuronal><novel><pathway><patient population><pharmacokinetics and pharmacodynamics><pre-clinical><pre-clinical development><pre-clinical drug development><precision therapies><precision treatment><preclinical><preclinical development><protein expression><psychiatric illness><psychological disorder><quality of life improvement><rare genetic disease><rare genetic disorder><scaffold><scaffolding><scale up><screening><screenings><small molecule><small molecule libraries><social>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Courtney A Miller

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,781,729
FY 2026

Project Title

Preclinical development of a precision therapy for a monogenic mental health disorder

Grant Number:

5U01MH136567-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/16/2024

End Date:

1/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY In this project, we propose to develop primary and secondary lead small molecules into preclinical drug candidates for a precision SYNGAP1-DEE therapy. This research is consistent with the mission of NIMH because this genetic disorder impacts mental health and behavior through impair...

Research Terms

<ASD><Adverse effects><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Automation><Automobile Driving><Behavior><Behavioral><Biological Agent><Biological Products><Biology><Brain><Brain Nervous System><CNS Nervous System><Care Givers><Caregivers><Central Nervous System><Chemical Agents><Chemical Structure><Chemicals><Clinical Research><Clinical Study><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><DNA mutation><Development><Diagnosis><Disease><Disorder><Distress><Disturbance in cognition><Dose><Drug Kinetics><Drugs><Early Infantile Autism><Encephalon><Ensure><Epilepsy><Epileptic Seizures><Epileptics><Escalante syndrome><Exhibits><Family><Formulation><Fragile X><Fragile X Syndrome><Funding><Gene Expression><Gene Targeting><Genes><Genetic><Genetic Change><Genetic Diseases><Genetic defect><Genetic mutation><Goals><Human><Impaired cognition><Impairment><In Vitro><Infantile Autism><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Kanner's Syndrome><Knowledge><Lead><Link><Live Birth><Martin-Bell Syndrome><Martin-Bell-Renpenning syndrome><Medication><Medicinal Chemistry><Mental Health><Mental Hygiene><Mental disorders><Mental health disorders><Mice><Mice Mammals><Microsomes><Mission><Modern Man><Murine><Mus><Mutation><NIMH><National Institute of Mental Health><Nerve Cells><Nerve Unit><Nervous System Physiology><Neural Cell><Neuraxis><Neurocyte><Neurodevelopmental Disorder><Neurologic function><Neurological Development Disorder><Neurological function><Neurons><Oral><Outcome><PK/PD><Pathogenicity><Pathway interactions><Patients><Pb element><Penetrance><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Pharmaceutical Preparations><Pharmacokinetics><Pharmacology><Phenotype><Pre-clinical Drug Testing/Development><Precision therapeutics><Preclinical Drug Development><Preclinical Drug Testing/Development><Prevalence><Property><Proteins><Psychiatric Disease><Psychiatric Disorder><Psychological Health><QOL improvement><R-Series Research Projects><R01 Mechanism><R01 Program><Renpenning syndrome 2><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Risk><SYNGAP1><Safety><Seizure Disorder><Seizures><Solubility><Spinal Column><Spine><Synaptic Ras GTPase Activating Protein 1><Technology><Testing><Variant><Variation><Vertebral column><Work><X-linked mental deficiency-megalotestes syndrome><X-linked mental retardation with fragile X syndrome><X-linked mental retardation-fragile site 1 syndrome><autism spectral disorder><autism spectrum disorder><autism-fragile X (AFRAX) syndrome><autistic spectrum disorder><backbone><biologics><biopharmaceutical><biotherapeutic agent><brain cell><brain tissue><chemical library><cognitive dysfunction><cognitive enhancement><cognitive loss><design><designing><determine efficacy><developmental><driving><drug candidate><drug/agent><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><epilepsia><epileptogenic><evaluate efficacy><examine efficacy><fra(X) syndrome><fra(X)(28) syndrome><fra(X)(q27) syndrome><fra(X)(q27-28) syndrome><fragile X-mental retardation syndrome><fragile Xq syndrome><fragile site mental retardation 1><genetic approach><genetic condition><genetic disorder><genetic strategy><genome mutation><heavy metal Pb><heavy metal lead><improved><improvements in QOL><improvements in quality of life><in vivo><individual patient><intellectual and developmental disability><lead optimization><lead series><limited intellectual functioning><macro-orchidism-marker X (MOMX) syndrome><macro-orchidism-marker X syndrome><mar(X) syndrome><marker X syndrome><mental illness><mental retardation-macroorchidism syndrome><model of animal><mouse genetics><nervous system function><neurodevelopmental disease><neuronal><novel><pathway><patient population><pharmacokinetics and pharmacodynamics><pre-clinical><pre-clinical development><pre-clinical drug development><precision therapies><precision treatment><preclinical><preclinical development><protein expression><psychiatric illness><psychological disorder><quality of life improvement><rare genetic disease><rare genetic disorder><scaffold><scaffolding><scale up><screening><screenings><small molecule><small molecule libraries><social>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

GAVIN R RUMBAUGH

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,781,729
FY 2026

Project Title

Preclinical development of a precision therapy for a monogenic mental health disorder

Grant Number:

5U01MH136567-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/16/2024

End Date:

1/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY In this project, we propose to develop primary and secondary lead small molecules into preclinical drug candidates for a precision SYNGAP1-DEE therapy. This research is consistent with the mission of NIMH because this genetic disorder impacts mental health and behavior through impair...

Research Terms

<ASD><Adverse effects><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Automation><Automobile Driving><Behavior><Behavioral><Biological Agent><Biological Products><Biology><Brain><Brain Nervous System><CNS Nervous System><Care Givers><Caregivers><Central Nervous System><Chemical Agents><Chemical Structure><Chemicals><Clinical Research><Clinical Study><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><DNA mutation><Development><Diagnosis><Disease><Disorder><Distress><Disturbance in cognition><Dose><Drug Kinetics><Drugs><Early Infantile Autism><Encephalon><Ensure><Epilepsy><Epileptic Seizures><Epileptics><Escalante syndrome><Exhibits><Family><Formulation><Fragile X><Fragile X Syndrome><Funding><Gene Expression><Gene Targeting><Genes><Genetic><Genetic Change><Genetic Diseases><Genetic defect><Genetic mutation><Goals><Human><Impaired cognition><Impairment><In Vitro><Infantile Autism><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Kanner's Syndrome><Knowledge><Lead><Link><Live Birth><Martin-Bell Syndrome><Martin-Bell-Renpenning syndrome><Medication><Medicinal Chemistry><Mental Health><Mental Hygiene><Mental disorders><Mental health disorders><Mice><Mice Mammals><Microsomes><Mission><Modern Man><Murine><Mus><Mutation><NIMH><National Institute of Mental Health><Nerve Cells><Nerve Unit><Nervous System Physiology><Neural Cell><Neuraxis><Neurocyte><Neurodevelopmental Disorder><Neurologic function><Neurological Development Disorder><Neurological function><Neurons><Oral><Outcome><PK/PD><Pathogenicity><Pathway interactions><Patients><Pb element><Penetrance><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Pharmaceutical Preparations><Pharmacokinetics><Pharmacology><Phenotype><Pre-clinical Drug Testing/Development><Precision therapeutics><Preclinical Drug Development><Preclinical Drug Testing/Development><Prevalence><Property><Proteins><Psychiatric Disease><Psychiatric Disorder><Psychological Health><QOL improvement><R-Series Research Projects><R01 Mechanism><R01 Program><Renpenning syndrome 2><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Risk><SYNGAP1><Safety><Seizure Disorder><Seizures><Solubility><Spinal Column><Spine><Synaptic Ras GTPase Activating Protein 1><Technology><Testing><Variant><Variation><Vertebral column><Work><X-linked mental deficiency-megalotestes syndrome><X-linked mental retardation with fragile X syndrome><X-linked mental retardation-fragile site 1 syndrome><autism spectral disorder><autism spectrum disorder><autism-fragile X (AFRAX) syndrome><autistic spectrum disorder><backbone><biologics><biopharmaceutical><biotherapeutic agent><brain cell><brain tissue><chemical library><cognitive dysfunction><cognitive enhancement><cognitive loss><design><designing><determine efficacy><developmental><driving><drug candidate><drug/agent><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><epilepsia><epileptogenic><evaluate efficacy><examine efficacy><fra(X) syndrome><fra(X)(28) syndrome><fra(X)(q27) syndrome><fra(X)(q27-28) syndrome><fragile X-mental retardation syndrome><fragile Xq syndrome><fragile site mental retardation 1><genetic approach><genetic condition><genetic disorder><genetic strategy><genome mutation><heavy metal Pb><heavy metal lead><improved><improvements in QOL><improvements in quality of life><in vivo><individual patient><intellectual and developmental disability><lead optimization><lead series><limited intellectual functioning><macro-orchidism-marker X (MOMX) syndrome><macro-orchidism-marker X syndrome><mar(X) syndrome><marker X syndrome><mental illness><mental retardation-macroorchidism syndrome><model of animal><mouse genetics><nervous system function><neurodevelopmental disease><neuronal><novel><pathway><patient population><pharmacokinetics and pharmacodynamics><pre-clinical><pre-clinical development><pre-clinical drug development><precision therapies><precision treatment><preclinical><preclinical development><protein expression><psychiatric illness><psychological disorder><quality of life improvement><rare genetic disease><rare genetic disorder><scaffold><scaffolding><scale up><screening><screenings><small molecule><small molecule libraries><social>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Margherita R Fontana

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,716,529
FY 2026

Project Title

Predicting Caries Lesion Patterns and Trajectories in Underserved Children, from Infancy to Early Adolescence, in Primary Healthcare Settings

Grant Number:

5U01DE021412-15

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2011

End Date:

3/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The recent NIDCR Oral Health in America report highlighted adolescence as a largely neglected life stage in oral health research and practice, with persistent and largely unchanged high caries experience, and called for strong actions to address this age cohort’s needs. Our team has ...

Research Terms

<0-11 years old><1 year of age><1 year old><12 year old><12 years of age><12-20 years old><15 year old><15 years of age><19 year old><19 years of age><21+ years old><6 year old><6 years of age><9 year old><9 years of age><Access to Care><Active Follow-up><Address><Adolescence><Adolescent><Adolescent Youth><Adopted><Adult><Adult Dentition><Adult Human><Affect><Age><Alcohol Drinking><Alcohol consumption><Anterior><Behavior><Beverages><Biological><Caries><Caring><Child><Child Youth><Childhood><Children (0-21)><Chronic><Data><Deciduous Dentition><Dental><Dental Care><Dental Decay><Dental Procedure><Dental caries><Development><Diet><Discipline of Nursing><Disease><Disorder><Drugs><Emotional Depression><Enrollment><Ensure><EtOH drinking><EtOH use><Family Demographies><Food Preferences><Future><Goals><Health><Health Care><Health Services Accessibility><Health behavior><Historical Demography><Incidence><Intervention><Lesion><Life><Life Cycle><Life Cycle Stages><Long-term prospective studies><Longitudinal Studies><Longitudinal Surveys><Medical><Medical History><Medication><Methods><NIDCR><NIDR><National Institute of Dental Research><National Institute of Dental and Craniofacial Research><Nursing><Nursing Field><Nursing Profession><Obesity><Oral><Oral health><Pattern><Permanent Dentition><Personal Medical History><Personal Medical History Epidemiology><Personal Satisfaction><Persons><Pharmaceutical Preparations><Phase><Policies><Precision care><Prevalence><Preventive><Primary Dentition><Primary Health Care><Primary Tooth><Publishing><Questionnaires><Recommendation><Reporting><Research><Research Design><Risk><Risk Behaviors><Risk Factors><Risky Behavior><School-Age Population><Screening procedure><Secondary Dentition><Smoking><Sports><Study Type><Surface><Temporary Tooth><Therapeutic><Time><Tooth><Tooth structure><Work><access to health services><access to services><access to treatment><accessibility to health services><active followup><adiposity><adolescence (12-20)><adolescent health><adulthood><age 1><age 1 year><age 12><age 12 years><age 15><age 15 years><age 19><age 19 years><age 6><age 6 years><age 9><age 9 years><aged 1 year><aged one year><ages><alcohol ingestion><alcohol intake><alcohol product use><alcohol use><alcoholic beverage consumption><alcoholic drink intake><anxiety symptoms><anxious symptom><at risk behavior><availability of services><behavioral health><biologic><care access><clinical decision-making><co-morbid><co-morbidity><cohort><comorbidity><computer based prediction><corpulence><cost><cost effective><cost effectiveness><deciduous tooth><dental health><dental service><depression symptom><depressive><depressive symptoms><design><designing><developmental><diet choice><diet preference><dietary choice><dietary preferences><diets><drug/agent><early adolescence><enroll><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol use><experience><fifteen year old><fifteen years of age><follow up><follow-up><followed up><followup><food choice><future implementation><health and care delivery><health care delivery><health care model><health care settings><health delivery systems><health related behavior><health service access><health services availability><health services delivery><implementation efforts><improved><individualized care><individualized patient care><infancy><infantile><innovate><innovation><innovative><juvenile><juvenile human><kids><life course><long-term study><longitudinal outcome studies><longitudinal research study><longitudinal, prospective study><neglect><nine year old><nine years of age><nineteen year old><nineteen years old><novel><one year of age><one year old><pediatric><permanent tooth><person centered><personalized care><personalized patient care><predictive modeling><primary care giver><primary caregiver><recruit><risk stratification><school age><screening tools><service availability><sex><six year old><six years of age><socio-demographics><sociodemographics><soda><soft drink><stratify risk><study design><success><teeth><tooth decay><treatment access><twelve year old><twelve years of age><vaping><well-being><wellbeing><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kara W Chew

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,429,199
FY 2026

Project Title

A Phase 1/2a, randomized study of a Tfh-targeting genetic vaccine adjuvant designed to induce broad, durable immune responses

Grant Number:

5U01AI172800-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/7/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT This U01-supported clinical trial will test a unique T follicular helper (Tfh)-targeting vaccine approach, “s3”, that we predict will generate exceptionally broad and long-lived antigen-specific antibody responses, characteristics likely to result in resilient vaccines that ...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><2019-nCoV S protein><2019-nCoV spike glycoprotein><2019-nCoV spike protein><2019-nCoV vaccine><2019-nCoV variant><2019-nCoV variant forms><2019-nCoV variant strains><Acceleration><Address><Adenoviridae><Adenoviruses><Adjuvant><Adverse Experience><Adverse event><Anti-CD3 Antibody><Antibodies><Antibody Fragments><Antibody Response><Antibody titer measurement><Antigens><B Cell Proliferation><B blood cells><B cell><B cells><B-Cell Development><B-Cells><B-Lymphocytes><B-cell><Blood><Blood Plasma Cell><Blood Reticuloendothelial System><Blood Serum><Booster Immunization><CD3><CD3 Antigens><CD3 Complex><CD3 molecule><COVID-19><COVID-19 S protein><COVID-19 spike><COVID-19 spike glycoprotein><COVID-19 spike protein><COVID-19 vaccine><COVID-19 variant><COVID-19 variant forms><COVID-19 variant strains><COVID-19 virus><COVID19 virus><CV-19><Characteristics><Chimera Protein><Chimeric Proteins><Class Switching><Class Switchings><Clinical Trials><CoV-2><CoV2><Coronavirus Infectious Disease 2019><Democracy><Development><Disease><Disorder><Dose><Economics><Event><FDA approved><Failure><Fusion Protein><Future><Germinal Center><Grant><Grippe><Health system><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><HuM291><Human><IgA><Immune response><Immunization><Immunoglobulin A><Immunoglobulin Class Switching><Immunoglobulin Class Switchings><Immunoglobulin Fragments><Immunology><Individual><Inducer Cells><Inducer T-Lymphocytes><Infection><Infection prevention><Inflammatory><Influenza><Isotype Switching><Isotype Switchings><Knowledge><Link><Macaca><Macaque><MoAb HuM291><Modern Man><Monoclonal Antibody HuM291><Mucosa><Mucosal Tissue><Mucous Membrane><OKT3 antigen><Older Population><Participant><Pathway interactions><Phase><Plasma Cells><Plasmacytes><Population><Prevent infection><Public Health><RNA immunization><RNA vaccination><RNA vaccine><RNA-based vaccine><Randomized><Reaction><Role><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 S><SARS-CoV-2 S protein><SARS-CoV-2 spike><SARS-CoV-2 spike glycoprotein><SARS-CoV-2 spike protein><SARS-CoV-2 vaccine><SARS-CoV-2 variant><SARS-CoV-2 variant forms><SARS-CoV-2 variant strains><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 vaccine><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Safety><Saliva><Sampling><Secondary Immunization><Series><Serious Adverse Event><Serum><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 vaccine><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe Adverse Event><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 S protein><Severe acute respiratory syndrome coronavirus 2 spike glycoprotein><Severe acute respiratory syndrome coronavirus 2 spike protein><Severe acute respiratory syndrome coronavirus 2 vaccine><Severe acute respiratory syndrome related corona virus 2><Site><Special Event><Specificity><Structure of germinal center of lymph node><System><T cell response><T-Cells><T-Lymphocyte><T3 Antigens><T3 Complex><T3 molecule><Technology><Testing><Transmission><Vaccine Adjuvant><Vaccines><Virus><Wuhan coronavirus><adaptive immune response><after COVID-19 infection><after SARS-CoV-2 infection><after SARS-CoV2 infection><after infection by SARS-CoV-2><after severe acute respiratory distress syndrome CoV-2 infection><antibody titering><antigen-specific T cells><booster dose><booster shot><booster vaccination><booster vaccine><coronavirus disease 2019><coronavirus disease 2019 S protein><coronavirus disease 2019 spike glycoprotein><coronavirus disease 2019 spike protein><coronavirus disease 2019 vaccine><coronavirus disease 2019 variant><coronavirus disease 2019 variant forms><coronavirus disease 2019 variant strains><coronavirus disease 2019 virus><coronavirus disease-19><coronavirus disease-19 vaccine><coronavirus disease-19 virus><coronavirus infectious disease-19><design><designing><develop a vaccine><develop vaccines><development of a vaccine><developmental><draining lymph node><economic><following COVID-19 infection><following SARS-CoV-2 infection><following SARS-CoV2 infection><following infection by SARS-CoV-2><following severe acute respiratory distress syndrome CoV-2 infection><genetic vaccine><hCoV19><host response><immune system response><immunogen><immunogenicity><immunoresponse><improved><interest><mRNA immunization><mRNA vaccination><mRNA vaccine><mRNA-based vaccine><nCoV vaccine><nCoV-19 vaccine><nCoV19 vaccine><nCoV2><neutralizing antibody><new approaches><new vaccines><next generation vaccines><non-human primate><nonhuman primate><novel><novel approaches><novel strategies><novel strategy><novel vaccines><older groups><older individuals><older person><pandemic><pandemic disease><pathogen><pathway><peripheral blood><plasmocyte><post SARS-CoV-2 infection><prevent><preventing><previous COVID-19 infection><previous SARS-CoV-2 infection><previous SARS-CoV2 infection><previous severe acute respiratory distress syndrome CoV-2 infection><prior COVID-19 infection><prior SARS-CoV-2 infection><prior SARS-CoV2 infection><prior severe acute respiratory distress syndrome CoV-2 infection><randomisation><randomization><randomly assigned><receptor binding><receptor bound><recruit><regional lymph node><resilience><resilient><response><safety testing><secondary end point><secondary endpoint><serious adverse experience><serious adverse reaction><severe acute respiratory syndrome coronavirus 2 variant><severe acute respiratory syndrome coronavirus 2 variant forms><severe acute respiratory syndrome coronavirus 2 variant strains><social role><spike proteins on SARS-CoV-2><success><thrombotic><thymus derived lymphocyte><tool><transmission process><vaccine against 2019-nCov><vaccine against COVID-19><vaccine against SARS-CoV-2><vaccine against SARS-coronavirus-2><vaccine against Severe Acute Respiratory Syndrome CoV 2><vaccine against Severe acute respiratory syndrome coronavirus 2><vaccine boost><vaccine candidates against SARS-CoV-2><vaccine development><vaccine failure><vaccine for novel coronavirus><vaccine response><vaccine responsiveness><vaccine strategy><vaccine-induced response><vaccines preventing COVID><vaccines to prevent COVID><vaccinology><vector>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

STEVEN Grant DEEKS

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,429,199
FY 2026

Project Title

A Phase 1/2a, randomized study of a Tfh-targeting genetic vaccine adjuvant designed to induce broad, durable immune responses

Grant Number:

5U01AI172800-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/7/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT This U01-supported clinical trial will test a unique T follicular helper (Tfh)-targeting vaccine approach, “s3”, that we predict will generate exceptionally broad and long-lived antigen-specific antibody responses, characteristics likely to result in resilient vaccines that ...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><2019-nCoV S protein><2019-nCoV spike glycoprotein><2019-nCoV spike protein><2019-nCoV vaccine><2019-nCoV variant><2019-nCoV variant forms><2019-nCoV variant strains><Acceleration><Address><Adenoviridae><Adenoviruses><Adjuvant><Adverse Experience><Adverse event><Anti-CD3 Antibody><Antibodies><Antibody Fragments><Antibody Response><Antibody titer measurement><Antigens><B Cell Proliferation><B blood cells><B cell><B cells><B-Cell Development><B-Cells><B-Lymphocytes><B-cell><Blood><Blood Plasma Cell><Blood Reticuloendothelial System><Blood Serum><Booster Immunization><CD3><CD3 Antigens><CD3 Complex><CD3 molecule><COVID-19><COVID-19 S protein><COVID-19 spike><COVID-19 spike glycoprotein><COVID-19 spike protein><COVID-19 vaccine><COVID-19 variant><COVID-19 variant forms><COVID-19 variant strains><COVID-19 virus><COVID19 virus><CV-19><Characteristics><Chimera Protein><Chimeric Proteins><Class Switching><Class Switchings><Clinical Trials><CoV-2><CoV2><Coronavirus Infectious Disease 2019><Democracy><Development><Disease><Disorder><Dose><Economics><Event><FDA approved><Failure><Fusion Protein><Future><Germinal Center><Grant><Grippe><Health system><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><HuM291><Human><IgA><Immune response><Immunization><Immunoglobulin A><Immunoglobulin Class Switching><Immunoglobulin Class Switchings><Immunoglobulin Fragments><Immunology><Individual><Inducer Cells><Inducer T-Lymphocytes><Infection><Infection prevention><Inflammatory><Influenza><Isotype Switching><Isotype Switchings><Knowledge><Link><Macaca><Macaque><MoAb HuM291><Modern Man><Monoclonal Antibody HuM291><Mucosa><Mucosal Tissue><Mucous Membrane><OKT3 antigen><Older Population><Participant><Pathway interactions><Phase><Plasma Cells><Plasmacytes><Population><Prevent infection><Public Health><RNA immunization><RNA vaccination><RNA vaccine><RNA-based vaccine><Randomized><Reaction><Role><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 S><SARS-CoV-2 S protein><SARS-CoV-2 spike><SARS-CoV-2 spike glycoprotein><SARS-CoV-2 spike protein><SARS-CoV-2 vaccine><SARS-CoV-2 variant><SARS-CoV-2 variant forms><SARS-CoV-2 variant strains><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 vaccine><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Safety><Saliva><Sampling><Secondary Immunization><Series><Serious Adverse Event><Serum><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 vaccine><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe Adverse Event><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 S protein><Severe acute respiratory syndrome coronavirus 2 spike glycoprotein><Severe acute respiratory syndrome coronavirus 2 spike protein><Severe acute respiratory syndrome coronavirus 2 vaccine><Severe acute respiratory syndrome related corona virus 2><Site><Special Event><Specificity><Structure of germinal center of lymph node><System><T cell response><T-Cells><T-Lymphocyte><T3 Antigens><T3 Complex><T3 molecule><Technology><Testing><Transmission><Vaccine Adjuvant><Vaccines><Virus><Wuhan coronavirus><adaptive immune response><after COVID-19 infection><after SARS-CoV-2 infection><after SARS-CoV2 infection><after infection by SARS-CoV-2><after severe acute respiratory distress syndrome CoV-2 infection><antibody titering><antigen-specific T cells><booster dose><booster shot><booster vaccination><booster vaccine><coronavirus disease 2019><coronavirus disease 2019 S protein><coronavirus disease 2019 spike glycoprotein><coronavirus disease 2019 spike protein><coronavirus disease 2019 vaccine><coronavirus disease 2019 variant><coronavirus disease 2019 variant forms><coronavirus disease 2019 variant strains><coronavirus disease 2019 virus><coronavirus disease-19><coronavirus disease-19 vaccine><coronavirus disease-19 virus><coronavirus infectious disease-19><design><designing><develop a vaccine><develop vaccines><development of a vaccine><developmental><draining lymph node><economic><following COVID-19 infection><following SARS-CoV-2 infection><following SARS-CoV2 infection><following infection by SARS-CoV-2><following severe acute respiratory distress syndrome CoV-2 infection><genetic vaccine><hCoV19><host response><immune system response><immunogen><immunogenicity><immunoresponse><improved><interest><mRNA immunization><mRNA vaccination><mRNA vaccine><mRNA-based vaccine><nCoV vaccine><nCoV-19 vaccine><nCoV19 vaccine><nCoV2><neutralizing antibody><new approaches><new vaccines><next generation vaccines><non-human primate><nonhuman primate><novel><novel approaches><novel strategies><novel strategy><novel vaccines><older groups><older individuals><older person><pandemic><pandemic disease><pathogen><pathway><peripheral blood><plasmocyte><post SARS-CoV-2 infection><prevent><preventing><previous COVID-19 infection><previous SARS-CoV-2 infection><previous SARS-CoV2 infection><previous severe acute respiratory distress syndrome CoV-2 infection><prior COVID-19 infection><prior SARS-CoV-2 infection><prior SARS-CoV2 infection><prior severe acute respiratory distress syndrome CoV-2 infection><randomisation><randomization><randomly assigned><receptor binding><receptor bound><recruit><regional lymph node><resilience><resilient><response><safety testing><secondary end point><secondary endpoint><serious adverse experience><serious adverse reaction><severe acute respiratory syndrome coronavirus 2 variant><severe acute respiratory syndrome coronavirus 2 variant forms><severe acute respiratory syndrome coronavirus 2 variant strains><social role><spike proteins on SARS-CoV-2><success><thrombotic><thymus derived lymphocyte><tool><transmission process><vaccine against 2019-nCov><vaccine against COVID-19><vaccine against SARS-CoV-2><vaccine against SARS-coronavirus-2><vaccine against Severe Acute Respiratory Syndrome CoV 2><vaccine against Severe acute respiratory syndrome coronavirus 2><vaccine boost><vaccine candidates against SARS-CoV-2><vaccine development><vaccine failure><vaccine for novel coronavirus><vaccine response><vaccine responsiveness><vaccine strategy><vaccine-induced response><vaccines preventing COVID><vaccines to prevent COVID><vaccinology><vector>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DENNIS J. HARTIGAN-O'CONNOR

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,429,199
FY 2026

Project Title

A Phase 1/2a, randomized study of a Tfh-targeting genetic vaccine adjuvant designed to induce broad, durable immune responses

Grant Number:

5U01AI172800-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/7/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT This U01-supported clinical trial will test a unique T follicular helper (Tfh)-targeting vaccine approach, “s3”, that we predict will generate exceptionally broad and long-lived antigen-specific antibody responses, characteristics likely to result in resilient vaccines that ...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><2019-nCoV S protein><2019-nCoV spike glycoprotein><2019-nCoV spike protein><2019-nCoV vaccine><2019-nCoV variant><2019-nCoV variant forms><2019-nCoV variant strains><Acceleration><Address><Adenoviridae><Adenoviruses><Adjuvant><Adverse Experience><Adverse event><Anti-CD3 Antibody><Antibodies><Antibody Fragments><Antibody Response><Antibody titer measurement><Antigens><B Cell Proliferation><B blood cells><B cell><B cells><B-Cell Development><B-Cells><B-Lymphocytes><B-cell><Blood><Blood Plasma Cell><Blood Reticuloendothelial System><Blood Serum><Booster Immunization><CD3><CD3 Antigens><CD3 Complex><CD3 molecule><COVID-19><COVID-19 S protein><COVID-19 spike><COVID-19 spike glycoprotein><COVID-19 spike protein><COVID-19 vaccine><COVID-19 variant><COVID-19 variant forms><COVID-19 variant strains><COVID-19 virus><COVID19 virus><CV-19><Characteristics><Chimera Protein><Chimeric Proteins><Class Switching><Class Switchings><Clinical Trials><CoV-2><CoV2><Coronavirus Infectious Disease 2019><Democracy><Development><Disease><Disorder><Dose><Economics><Event><FDA approved><Failure><Fusion Protein><Future><Germinal Center><Grant><Grippe><Health system><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><HuM291><Human><IgA><Immune response><Immunization><Immunoglobulin A><Immunoglobulin Class Switching><Immunoglobulin Class Switchings><Immunoglobulin Fragments><Immunology><Individual><Inducer Cells><Inducer T-Lymphocytes><Infection><Infection prevention><Inflammatory><Influenza><Isotype Switching><Isotype Switchings><Knowledge><Link><Macaca><Macaque><MoAb HuM291><Modern Man><Monoclonal Antibody HuM291><Mucosa><Mucosal Tissue><Mucous Membrane><OKT3 antigen><Older Population><Participant><Pathway interactions><Phase><Plasma Cells><Plasmacytes><Population><Prevent infection><Public Health><RNA immunization><RNA vaccination><RNA vaccine><RNA-based vaccine><Randomized><Reaction><Role><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 S><SARS-CoV-2 S protein><SARS-CoV-2 spike><SARS-CoV-2 spike glycoprotein><SARS-CoV-2 spike protein><SARS-CoV-2 vaccine><SARS-CoV-2 variant><SARS-CoV-2 variant forms><SARS-CoV-2 variant strains><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 vaccine><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Safety><Saliva><Sampling><Secondary Immunization><Series><Serious Adverse Event><Serum><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 vaccine><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe Adverse Event><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 S protein><Severe acute respiratory syndrome coronavirus 2 spike glycoprotein><Severe acute respiratory syndrome coronavirus 2 spike protein><Severe acute respiratory syndrome coronavirus 2 vaccine><Severe acute respiratory syndrome related corona virus 2><Site><Special Event><Specificity><Structure of germinal center of lymph node><System><T cell response><T-Cells><T-Lymphocyte><T3 Antigens><T3 Complex><T3 molecule><Technology><Testing><Transmission><Vaccine Adjuvant><Vaccines><Virus><Wuhan coronavirus><adaptive immune response><after COVID-19 infection><after SARS-CoV-2 infection><after SARS-CoV2 infection><after infection by SARS-CoV-2><after severe acute respiratory distress syndrome CoV-2 infection><antibody titering><antigen-specific T cells><booster dose><booster shot><booster vaccination><booster vaccine><coronavirus disease 2019><coronavirus disease 2019 S protein><coronavirus disease 2019 spike glycoprotein><coronavirus disease 2019 spike protein><coronavirus disease 2019 vaccine><coronavirus disease 2019 variant><coronavirus disease 2019 variant forms><coronavirus disease 2019 variant strains><coronavirus disease 2019 virus><coronavirus disease-19><coronavirus disease-19 vaccine><coronavirus disease-19 virus><coronavirus infectious disease-19><design><designing><develop a vaccine><develop vaccines><development of a vaccine><developmental><draining lymph node><economic><following COVID-19 infection><following SARS-CoV-2 infection><following SARS-CoV2 infection><following infection by SARS-CoV-2><following severe acute respiratory distress syndrome CoV-2 infection><genetic vaccine><hCoV19><host response><immune system response><immunogen><immunogenicity><immunoresponse><improved><interest><mRNA immunization><mRNA vaccination><mRNA vaccine><mRNA-based vaccine><nCoV vaccine><nCoV-19 vaccine><nCoV19 vaccine><nCoV2><neutralizing antibody><new approaches><new vaccines><next generation vaccines><non-human primate><nonhuman primate><novel><novel approaches><novel strategies><novel strategy><novel vaccines><older groups><older individuals><older person><pandemic><pandemic disease><pathogen><pathway><peripheral blood><plasmocyte><post SARS-CoV-2 infection><prevent><preventing><previous COVID-19 infection><previous SARS-CoV-2 infection><previous SARS-CoV2 infection><previous severe acute respiratory distress syndrome CoV-2 infection><prior COVID-19 infection><prior SARS-CoV-2 infection><prior SARS-CoV2 infection><prior severe acute respiratory distress syndrome CoV-2 infection><randomisation><randomization><randomly assigned><receptor binding><receptor bound><recruit><regional lymph node><resilience><resilient><response><safety testing><secondary end point><secondary endpoint><serious adverse experience><serious adverse reaction><severe acute respiratory syndrome coronavirus 2 variant><severe acute respiratory syndrome coronavirus 2 variant forms><severe acute respiratory syndrome coronavirus 2 variant strains><social role><spike proteins on SARS-CoV-2><success><thrombotic><thymus derived lymphocyte><tool><transmission process><vaccine against 2019-nCov><vaccine against COVID-19><vaccine against SARS-CoV-2><vaccine against SARS-coronavirus-2><vaccine against Severe Acute Respiratory Syndrome CoV 2><vaccine against Severe acute respiratory syndrome coronavirus 2><vaccine boost><vaccine candidates against SARS-CoV-2><vaccine development><vaccine failure><vaccine for novel coronavirus><vaccine response><vaccine responsiveness><vaccine strategy><vaccine-induced response><vaccines preventing COVID><vaccines to prevent COVID><vaccinology><vector>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kirsi Jarvinen-Seppo

UNIVERSITY OF ROCHESTER, ROCHESTER, NY

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,391,926
FY 2026

Project Title

Biomarkers of Atopy Beginning Early (BABE)

Grant Number:

5U19AI175113-04

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/7/2023

End Date:

3/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT – OVERALL Atopic dermatitis (AD) often precedes sensitization to food allergens and the development of clinical food allergy (FA) due to compromised skin barrier function allowing allergen sensitization through skin. A large body of data from Europe and North America suggest...

Research Terms

<0-11 years old><5 year old><5 years of age><Allergens><Allergic><Allergic Disease><Allergic asthma><Allergic to food><Allergy><Allergy to food><Asthma><Atopic Allergy><Atopic Dermatitis><Atopic Eczema><Atopic Neurodermatitis><Bathing><Baths><Bioinformatics><Bioinformatics core><Bioinformatics research core><Bioinformatics resource core><Biological Markers><Birth><Blood><Blood Reticuloendothelial System><Blood monocyte><Bronchial Asthma><Cell Body><Cells><Child><Child Youth><Childhood><Children (0-21)><Clinical Data><Cluster Analyses><Cluster Analysis><Consumption><Data><Development><Diet><Disease><Disorder><Disseminated Neurodermatitis><Eating><Epithelial Cells><Europe><Exposure to><Extrinsic asthma><Family><Farm><Farm Animal><Feces><Food Allergy><Food Hypersensitivity><Food Intake><Foundations><Funding><Future><GI microbiome><Generations><Grant><Home><Homing><House Dust><Human><Immune><Immune Markers><Immune response><Immune system><Immunes><Immunologic Markers><Impairment><Incidence><Individual><Infant><Inflammation><Inflammatory><Infrastructure><Innate Immune System><Innate Immunity><Knowledge><L-Tryptophan><Lead><Levotryptophan><Life><Life Style><Lifestyle><Livestock><Marrow monocyte><Memory><Mennonite><Milk><Modern Man><Native Immunity><Natural Immunity><Non-Specific Immunity><Nonspecific Immunity><North America><Organization Charts><Parturition><Pb element><Permeability><Population><Prevention><Production><Regulatory T-Lymphocyte><Risk><Sampling><Short-Chain Fatty Acids><Skin><Swab><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><TSLP><TSLP gene><Testing><Thymic Stromal Lymphopoietin><Training><Treg><Tryptophan><Volatile Fatty Acids><adaptive immunity><age 5><age 5 years><allergic dermatitis><allergic eczema><atopic asthma><atopic triad><atopy><bio-markers><biobank><biologic marker><biomarker><biomarker identification><biorepository><birth cohort study><birth cohort survey><clinical development><cohort><comparator group><comparison group><cutaneous barrier><cutaneous microbiome><cytokine><data management><dermal barrier><dermal microbiome><developmental><diets><digestive tract microbiome><early childhood><early onset><enteric microbiome><epidermal barrier><epidermal microbiome><extrinsic allergic asthma><five year old><five years of age><food allergen><gastrointestinal microbiome><global gene expression><global transcription profile><gut microbiome><gut microbiome of infant><gut-associated microbiome><heavy metal Pb><heavy metal lead><high risk><high risk infant><home dust><homes><host response><household dust><identification of biomarkers><identification of new biomarkers><immune system response><immune-based biomarkers><immunological biomarkers><immunological markers><immunoresponse><individualized prevention><infancy><infant gut microbiome><infantile><intestinal biome><intestinal microbiome><kids><marker identification><metabolome><metabonome><metagenome sequencing><metagenomic sequencing><microbial><microbiome><microbiome community composition><microbiome composition><microbiome species composition><microbiome structure><monocyte><neonate gut microbiome><newborn gut microbiome><organizational structure><pediatric><personalized prevention><precision prevention><preservation><programs><recruit><regulatory T-cells><residential dust><respiratory><sample collection><skin barrier><skin biome><skin microbiome><specimen collection><stool><thymus derived lymphocyte><transcriptome><transcriptomics><unpasteurized><urban children><vulnerable infant><youngster>
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HANSELL H STEDMAN

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,343,215
FY 2026

Project Title

IND-enabling studies of non-immunogenic gene therapy for ultra-rare DMD patients excluded from dystrophin trials

Grant Number:

3U01NS134672-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/11/2026

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Duchenne muscular dystrophy (DMD) is a rare childhood onset neuromuscular disease caused by genetic deficiency of the protein dystrophin. DMD is an incurable disease with a devastating impact on patients as a result of progressive weakness, wheelchair confinement, loss of independence/acti...

Research Terms

<AAV vector><AAV-based vector><Activities of Daily Living><Activities of everyday life><Address><Animal Model><Animal Models and Related Studies><Antigenic Determinants><Binding Determinants><Biochemical><Cessation of life><Childhood><Clinical Research><Clinical Study><Clinical Trials><Complex><Cytoskeletal Gene><Cytoskeletal Proteins><DNA Therapy><Death><Disease><Disorder><Duchene><Duchenne><Duchenne muscular dystrophy><Duchenne-Griesinger syndrome><Dysfunction><Dystrophin><Dystrophin-Related Protein><Dystrophin-Related Protein 1><Ellis-van Creveld (EvC) syndrome><Epitopes><Exclusion><Exons><Functional disorder><Gene Alteration><Gene Mutation><Gene Transfer Clinical><Gene therapy trial><Genes><Genetic><Genetic Diseases><Genetic Intervention><German><German population><Glycoproteins><Hair><IND Filing><IND application><IND package><IND submission><Immune Tolerance><Immunologic Tolerance><Investigational New Drug Application><Isoforms><Length><Mediating><Medicine><Membrane><Mission><Muscle><Muscle Cell Contraction><Muscle Contraction><Muscle Tissue><Muscular Contraction><Muscular Dystrophies><Myodystrophica><Myodystrophy><N-terminal><NH2-terminal><NINDS><National Institute of Neurological Diseases and Stroke><National Institute of Neurological Disorders and Stroke><Nature><Neuromuscular Diseases><Other Genetics><Outcome Measure><Patients><Peptides><Phase><Physiologic><Physiological><Physiopathology><Pre-Clinical Model><Preclinical Models><Prediction of Response to Therapy><Probability><Protein Isoforms><Proteins><Pseudohypertrophic Muscular Dystrophy><Publishing><Recombinant Proteins><Regulation><Risk><Rod><Serious Adverse Event><Severe Adverse Event><Spectrin><Structure><T cell response><T-Cells><T-Lymphocyte><Translational Research><Translational Science><Transmission><UTRN Protein><Utrophin><Wheel Chairs><Wheelchairs><X-linked dilated cardiomyopathy><X-linked muscular dystrophy><X-linked recessive muscular dystrophy><adeno-associated viral vector><adeno-associated virus vector><benign X-linked recessive muscular dystrophy><childhood pseudohypertrophic muscular dystrophy><classic X-linked recessive muscular dystrophy><daily living function><daily living functionality><experiment><experimental research><experimental study><experiments><functional ability><functional capacity><gene defect><gene repair therapy><gene therapy><gene transfer trial><gene-based therapy><genetic condition><genetic disorder><genetic therapy><genomic therapy><immune system tolerance><immune unresponsiveness><immunological paralysis><innovate><innovation><innovative><measurable outcome><membrane structure><mild X-linked recessive muscular dystrophy><miniaturize><miniaturized><model of animal><muscle dystrophy><muscular><mutant allele><myoneural disorder><neuromuscular degenerative disorder><neuromuscular disorder><outcome measurement><pathophysiology><patient population><pediatric><pre-clinical study><preclinical study><predict therapeutic response><predict therapy response><premature><prematurity><programs><progressive muscular dystrophy of childhood><protein folding><pseudohypertrophic adult muscular dystrophy><pseudohypertrophic muscular paralysis><serious adverse experience><serious adverse reaction><therapeutic agent development><therapeutic development><therapy prediction><thymus derived lymphocyte><translation research><translational investigation><transmission process><treatment prediction><treatment response prediction><triple helix>
View Full Project Details on NIH Reporter
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Linda B. Cottler

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$986,758
FY 2026

Project Title

National Drug Early Warning System Coordinating Center (NDEWS)

Grant Number:

5U01DA051126-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2020

End Date:

2/28/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

This is a competitive renewal to continue as NIDA’s National Drug Early Warning System (NDEWS) Coordinating Center (CC), in response to RFA DA-25-029. Under a Cooperative Agreement U01 mechanism, spearheaded by the Cottler Lab at the University of Florida since 2020, we propose a new MPI leadership ...

Research Terms

<Academia><Adverse effects><Anticonvulsant Agent><Anticonvulsant Drugs><Anticonvulsants><Anticonvulsive Agents><Anticonvulsive Drugs><Awareness><Behavioral><Canada><Cell Communication and Signaling><Cell Signaling><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Cognitive><Collaborations><Communities><Community Health><Community Networks><Cooperative Agreements><County><Data><Data Analyses><Data Analysis><Data Collection><Dedications><Demographic Factors><Drug Combinations><Drug Controls><Drug Monitoring><Drug usage><Drugs><Elements><Epidemiology><Europe><Exposure to><Florida><Forensic Medicine><Forensics><Goals><Harm Minimization><Harm Reduction><Health><Internet><Intervention Strategies><Intracellular Communication and Signaling><Investigators><Joints><Law Enforcement><Leadership><Lived experience><Lived experiences><Machine Learning><Manuscripts><Medical Examiners><Medication><Mexico><Monitor><Morbidity><NIDA><Naloxone><Narcan><Narcanti><National Institute of Drug Abuse><National Institute on Drug Abuse><Notification><Overdose><Parents><Pattern><Perception><Persons><Pharmaceutical Preparations><Policies><Policy Maker><Population><Population Surveillance><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Procedures><Productivity><Public Health><Public Health Surveillance><Publications><Quality Control><Reporter><Reporting><Research Personnel><Research Resources><Researchers><Resources><Risk><Robotics><Route><SAMHSA><Scientific Publication><Scientist><Seizures><Sentinel><Sentinel Surveillance><Sentinel Surveillances><Series><Signal Transduction><Signal Transduction Systems><Signaling><Site><Sociology><Source><Substance Abuse and Mental Health Services Administration><Surveillance Methods><System><Toxicology><Training><U-Series Cooperative Agreements><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><United States Substance Abuse and Mental Health Services Administration><Universities><Vital Statistics><WWW><biological signal transduction><community-based health><conference><convention><dashboard><data dissemination><data interpretation><data sharing><disparity in health><drug use><drug/agent><epidemiologic><epidemiological><evidence base><harm reduction programs><health disparity><ideation><innovate><innovation><innovative><insight><machine based learning><meeting><meetings><member><mortality><new approaches><next generation><novel><novel approaches><novel strategies><novel strategy><overdose death><overdose fatalities><parent><poison control><programs><regional difference><response><rurality><seizure drug><seizure medication><service providers><social determinants><social media><sociodeterminant><substance use><substance using><summit><surveillance data><symposia><symposium><teacher><trend><virtual><web><web site><website><world wide web>
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Joseph J Palamar

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$986,758
FY 2026

Project Title

National Drug Early Warning System Coordinating Center (NDEWS)

Grant Number:

5U01DA051126-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2020

End Date:

2/28/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

This is a competitive renewal to continue as NIDA’s National Drug Early Warning System (NDEWS) Coordinating Center (CC), in response to RFA DA-25-029. Under a Cooperative Agreement U01 mechanism, spearheaded by the Cottler Lab at the University of Florida since 2020, we propose a new MPI leadership ...

Research Terms

<Academia><Adverse effects><Anticonvulsant Agent><Anticonvulsant Drugs><Anticonvulsants><Anticonvulsive Agents><Anticonvulsive Drugs><Awareness><Behavioral><Canada><Cell Communication and Signaling><Cell Signaling><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Cognitive><Collaborations><Communities><Community Health><Community Networks><Cooperative Agreements><County><Data><Data Analyses><Data Analysis><Data Collection><Dedications><Demographic Factors><Drug Combinations><Drug Controls><Drug Monitoring><Drug usage><Drugs><Elements><Epidemiology><Europe><Exposure to><Florida><Forensic Medicine><Forensics><Goals><Harm Minimization><Harm Reduction><Health><Internet><Intervention Strategies><Intracellular Communication and Signaling><Investigators><Joints><Law Enforcement><Leadership><Lived experience><Lived experiences><Machine Learning><Manuscripts><Medical Examiners><Medication><Mexico><Monitor><Morbidity><NIDA><Naloxone><Narcan><Narcanti><National Institute of Drug Abuse><National Institute on Drug Abuse><Notification><Overdose><Parents><Pattern><Perception><Persons><Pharmaceutical Preparations><Policies><Policy Maker><Population><Population Surveillance><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Procedures><Productivity><Public Health><Public Health Surveillance><Publications><Quality Control><Reporter><Reporting><Research Personnel><Research Resources><Researchers><Resources><Risk><Robotics><Route><SAMHSA><Scientific Publication><Scientist><Seizures><Sentinel><Sentinel Surveillance><Sentinel Surveillances><Series><Signal Transduction><Signal Transduction Systems><Signaling><Site><Sociology><Source><Substance Abuse and Mental Health Services Administration><Surveillance Methods><System><Toxicology><Training><U-Series Cooperative Agreements><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><United States Substance Abuse and Mental Health Services Administration><Universities><Vital Statistics><WWW><biological signal transduction><community-based health><conference><convention><dashboard><data dissemination><data interpretation><data sharing><disparity in health><drug use><drug/agent><epidemiologic><epidemiological><evidence base><harm reduction programs><health disparity><ideation><innovate><innovation><innovative><insight><machine based learning><meeting><meetings><member><mortality><new approaches><next generation><novel><novel approaches><novel strategies><novel strategy><overdose death><overdose fatalities><parent><poison control><programs><regional difference><response><rurality><seizure drug><seizure medication><service providers><social determinants><social media><sociodeterminant><substance use><substance using><summit><surveillance data><symposia><symposium><teacher><trend><virtual><web><web site><website><world wide web>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DANIEL C. JAVITT

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$823,173
FY 2026

Project Title

Use of alpha-frequency deep transcranial interference stimulation (tIS) to understand and modify temporal dynamics of face emotion recognition and social/affective function.

Grant Number:

5U01MH135436-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/2/2024

End Date:

2/29/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

A critical aspect of social cognition is the ability to infer emotion based upon facial expression, termed face emotion recognition (FER). We have recently shown that FER deficits in schizophrenia (Sz) and autism disorder spectrum (ASD) are associated with impaired activation and resting-state funct...

Research Terms

<AD dementia><ASD><Affective><After Care><After-Treatment><Aftercare><Allelism Test><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Autism><Autistic Disorder><Behavioral><Body Tissues><Brain><Brain Nervous System><Canada><Cell Nucleus><Cephalic><China><Clinical><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive deficits><Cognitive function abnormal><Complement><Complement Proteins><Complementation Test><Consultations><Controlled Study><Corpus Striatum><Corpus striatum structure><Cranial><Cyclicity><Data><Deep Brain Stimulation><Development><Devices><Diminished Vision><Disease><Disorder><Disturbance in cognition><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Dysfunction><E-stim><EEG><Early Infantile Autism><Early-Stage Clinical Trials><Effectiveness><Electric Stimulation><Electroencephalogram><Electroencephalography><Emotions><Encephalon><Event><Face><Face Processing><Facial Expression><Frequencies><Functional MRI><Functional Magnetic Resonance Imaging><Functional disorder><Funding><Future><Generations><Genetic Complementation Test><Goals><H+ element><Hydrogen Ions><IQ Deficit><Impaired cognition><Impairment><Individual><Infantile Autism><Investigational Drugs><Investigational New Drugs><Kanner's Syndrome><Link><Location><Low Vision><MR Spectroscopy><Magnetic Resonance Spectroscopy><Mainland China><Measures><Mediating><Medical><Mental disorders><Mental health disorders><Modeling><NIMH><National Institute of Mental Health><Neurocognition><Neurocognitive><Neurocognitive Deficit><Nucleus><Partial Sight><Pattern><Performance><Periodicity><Phase 1 Clinical Trials><Phase I Clinical Trials><Physiologic><Physiological><Physiopathology><Play><Primary Senile Degenerative Dementia><Process><Protons><Psychiatric Disease><Psychiatric Disorder><Publications><Pulvinar><Pulvinar structure><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Reduced Vision><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Rest><Rhythmicity><Risk><Role><Safety><Schizophrenia><Schizophrenic Disorders><Scientific Publication><Sensory><Specificity><Stimulus><Striate Body><Striatum><Structure><Subnormal Vision><System><Techniques><Technology><Testing><Thalamic structure><Thalamus><Tissues><Trans Test><Visual><Visual Cortex><Visual impairment><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><clinical relevance><clinically relevant><cognitive defects><cognitive dysfunction><cognitive function><cognitive loss><cohort><complementation><complementation analysis><complementation approach><consultation><dementia praecox><design><designing><developmental><electrostimulation><fMRI><fMRI/EEG><face expression><faces><facial><facial processing><first in man><first-in-human><functional magnetic resonance imaging/electroencephalography><healthy volunteer><improved><industrial partnership><industry partner><industry partnership><intelligence quotient deficit><mental illness><minimal risk><neurocognitive decline><neurocognitive impairment><neurophysiological><neurophysiology><neuropsychiatric disease><neuropsychiatric disorder><new technology><non-invasive brain stimulation><novel><novel technologies><pathophysiology><phase I protocol><post treatment><primary degenerative dementia><psychiatric illness><psychological disorder><pulvinar thalami><randomisation><randomization><randomly assigned><response><safety assessment><schizophrenic><senile dementia of the Alzheimer type><social><social cognition><social role><striatal><thalamic><tool><vision impairment><visual cortical><visual process><visual processing><visually impaired>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Antigona Martinez

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$823,173
FY 2026

Project Title

Use of alpha-frequency deep transcranial interference stimulation (tIS) to understand and modify temporal dynamics of face emotion recognition and social/affective function.

Grant Number:

5U01MH135436-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/2/2024

End Date:

2/29/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

A critical aspect of social cognition is the ability to infer emotion based upon facial expression, termed face emotion recognition (FER). We have recently shown that FER deficits in schizophrenia (Sz) and autism disorder spectrum (ASD) are associated with impaired activation and resting-state funct...

Research Terms

<AD dementia><ASD><Affective><After Care><After-Treatment><Aftercare><Allelism Test><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Autism><Autistic Disorder><Behavioral><Body Tissues><Brain><Brain Nervous System><Canada><Cell Nucleus><Cephalic><China><Clinical><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive deficits><Cognitive function abnormal><Complement><Complement Proteins><Complementation Test><Consultations><Controlled Study><Corpus Striatum><Corpus striatum structure><Cranial><Cyclicity><Data><Deep Brain Stimulation><Development><Devices><Diminished Vision><Disease><Disorder><Disturbance in cognition><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Dysfunction><E-stim><EEG><Early Infantile Autism><Early-Stage Clinical Trials><Effectiveness><Electric Stimulation><Electroencephalogram><Electroencephalography><Emotions><Encephalon><Event><Face><Face Processing><Facial Expression><Frequencies><Functional MRI><Functional Magnetic Resonance Imaging><Functional disorder><Funding><Future><Generations><Genetic Complementation Test><Goals><H+ element><Hydrogen Ions><IQ Deficit><Impaired cognition><Impairment><Individual><Infantile Autism><Investigational Drugs><Investigational New Drugs><Kanner's Syndrome><Link><Location><Low Vision><MR Spectroscopy><Magnetic Resonance Spectroscopy><Mainland China><Measures><Mediating><Medical><Mental disorders><Mental health disorders><Modeling><NIMH><National Institute of Mental Health><Neurocognition><Neurocognitive><Neurocognitive Deficit><Nucleus><Partial Sight><Pattern><Performance><Periodicity><Phase 1 Clinical Trials><Phase I Clinical Trials><Physiologic><Physiological><Physiopathology><Play><Primary Senile Degenerative Dementia><Process><Protons><Psychiatric Disease><Psychiatric Disorder><Publications><Pulvinar><Pulvinar structure><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Reduced Vision><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Rest><Rhythmicity><Risk><Role><Safety><Schizophrenia><Schizophrenic Disorders><Scientific Publication><Sensory><Specificity><Stimulus><Striate Body><Striatum><Structure><Subnormal Vision><System><Techniques><Technology><Testing><Thalamic structure><Thalamus><Tissues><Trans Test><Visual><Visual Cortex><Visual impairment><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><clinical relevance><clinically relevant><cognitive defects><cognitive dysfunction><cognitive function><cognitive loss><cohort><complementation><complementation analysis><complementation approach><consultation><dementia praecox><design><designing><developmental><electrostimulation><fMRI><fMRI/EEG><face expression><faces><facial><facial processing><first in man><first-in-human><functional magnetic resonance imaging/electroencephalography><healthy volunteer><improved><industrial partnership><industry partner><industry partnership><intelligence quotient deficit><mental illness><minimal risk><neurocognitive decline><neurocognitive impairment><neurophysiological><neurophysiology><neuropsychiatric disease><neuropsychiatric disorder><new technology><non-invasive brain stimulation><novel><novel technologies><pathophysiology><phase I protocol><post treatment><primary degenerative dementia><psychiatric illness><psychological disorder><pulvinar thalami><randomisation><randomization><randomly assigned><response><safety assessment><schizophrenic><senile dementia of the Alzheimer type><social><social cognition><social role><striatal><thalamic><tool><vision impairment><visual cortical><visual process><visual processing><visually impaired>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PEJMAN SEHATPOUR

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$823,173
FY 2026

Project Title

Use of alpha-frequency deep transcranial interference stimulation (tIS) to understand and modify temporal dynamics of face emotion recognition and social/affective function.

Grant Number:

5U01MH135436-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/2/2024

End Date:

2/29/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

A critical aspect of social cognition is the ability to infer emotion based upon facial expression, termed face emotion recognition (FER). We have recently shown that FER deficits in schizophrenia (Sz) and autism disorder spectrum (ASD) are associated with impaired activation and resting-state funct...

Research Terms

<AD dementia><ASD><Affective><After Care><After-Treatment><Aftercare><Allelism Test><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Autism><Autistic Disorder><Behavioral><Body Tissues><Brain><Brain Nervous System><Canada><Cell Nucleus><Cephalic><China><Clinical><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive deficits><Cognitive function abnormal><Complement><Complement Proteins><Complementation Test><Consultations><Controlled Study><Corpus Striatum><Corpus striatum structure><Cranial><Cyclicity><Data><Deep Brain Stimulation><Development><Devices><Diminished Vision><Disease><Disorder><Disturbance in cognition><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Dysfunction><E-stim><EEG><Early Infantile Autism><Early-Stage Clinical Trials><Effectiveness><Electric Stimulation><Electroencephalogram><Electroencephalography><Emotions><Encephalon><Event><Face><Face Processing><Facial Expression><Frequencies><Functional MRI><Functional Magnetic Resonance Imaging><Functional disorder><Funding><Future><Generations><Genetic Complementation Test><Goals><H+ element><Hydrogen Ions><IQ Deficit><Impaired cognition><Impairment><Individual><Infantile Autism><Investigational Drugs><Investigational New Drugs><Kanner's Syndrome><Link><Location><Low Vision><MR Spectroscopy><Magnetic Resonance Spectroscopy><Mainland China><Measures><Mediating><Medical><Mental disorders><Mental health disorders><Modeling><NIMH><National Institute of Mental Health><Neurocognition><Neurocognitive><Neurocognitive Deficit><Nucleus><Partial Sight><Pattern><Performance><Periodicity><Phase 1 Clinical Trials><Phase I Clinical Trials><Physiologic><Physiological><Physiopathology><Play><Primary Senile Degenerative Dementia><Process><Protons><Psychiatric Disease><Psychiatric Disorder><Publications><Pulvinar><Pulvinar structure><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Reduced Vision><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Rest><Rhythmicity><Risk><Role><Safety><Schizophrenia><Schizophrenic Disorders><Scientific Publication><Sensory><Specificity><Stimulus><Striate Body><Striatum><Structure><Subnormal Vision><System><Techniques><Technology><Testing><Thalamic structure><Thalamus><Tissues><Trans Test><Visual><Visual Cortex><Visual impairment><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><clinical relevance><clinically relevant><cognitive defects><cognitive dysfunction><cognitive function><cognitive loss><cohort><complementation><complementation analysis><complementation approach><consultation><dementia praecox><design><designing><developmental><electrostimulation><fMRI><fMRI/EEG><face expression><faces><facial><facial processing><first in man><first-in-human><functional magnetic resonance imaging/electroencephalography><healthy volunteer><improved><industrial partnership><industry partner><industry partnership><intelligence quotient deficit><mental illness><minimal risk><neurocognitive decline><neurocognitive impairment><neurophysiological><neurophysiology><neuropsychiatric disease><neuropsychiatric disorder><new technology><non-invasive brain stimulation><novel><novel technologies><pathophysiology><phase I protocol><post treatment><primary degenerative dementia><psychiatric illness><psychological disorder><pulvinar thalami><randomisation><randomization><randomly assigned><response><safety assessment><schizophrenic><senile dementia of the Alzheimer type><social><social cognition><social role><striatal><thalamic><tool><vision impairment><visual cortical><visual process><visual processing><visually impaired>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bruce Marc Bissonnette

UNIVERSITY OF CHICAGO, CHICAGO, IL

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$676,491
FY 2026

Project Title

A non-invasive blood test for multi-cancer detection and determination of tissue of origin preceding overt cancer diagnosis

Grant Number:

5U01CA297685-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

4/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY In the United States, it is estimated there are ~730,000 new cases of prostate cancer, lung cancer, colorectal cancer (CRC), and ovarian cancer annually. Advances in therapies during the past decades have significantly improved clinical outcomes. For many common cancers, however, tre...

Research Terms

<Address><Age><Algorithms><Assay><Bioassay><Biological Assay><Biological Markers><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Tests><Body Tissues><Brain Cancer><CRC screening><Cancer Control><Cancer Control Science><Cancer Detection><Cancers><Cell Communication and Signaling><Cell Signaling><Clinical><Colon or Rectum><Colorectal><Colorectal Cancer><Communities><DNA><Data><Deoxyribonucleic Acid><Diagnosis><Diagnostic><Diagnostic Findings><Differential Gene Expression><Disease><Disorder><Distant Cancer><Distant Metastasis><Early Diagnosis><Elasticity><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Face><Foundations><Gastric Body Cancer><Gastric Cancer><Gastric Cardia Cancer><Gastric Fundus Cancer><Gastric Pylorus Cancer><Goals><Health><Health Resources><Hematologic Tests><Hematological Tests><Hematology Testing><Heparin><Heparinic Acid><Hepatic Cancer><Individual><Intracellular Communication and Signaling><Knowledge><Lung><Lung Respiratory System><Machine Learning><Malignant Gastric Neoplasm><Malignant Gastric Tumor><Malignant Neoplasms><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Tumor><Malignant Tumor of the Brain><Malignant Tumor of the Lung><Malignant Tumor of the Ovary><Malignant neoplasm of brain><Malignant neoplasm of liver><Malignant neoplasm of lung><Malignant neoplasm of ovary><Malignant neoplasm of prostate><Malignant prostatic tumor><Maps><Medicine><Modeling><NGS Method><NGS system><Outcome><Ovarian><Ovary Cancer><PLCO study><PLCO trial><Pathway interactions><Patient Compliance><Performance><Phase><Pilot Projects><Plasma><Plasma Serum><Pre-Clinical Model><Preclinical Models><Prostate><Prostate CA><Prostate Cancer><Prostate Gland><Prostate malignancy><Prostate, Lung, Colo-rectal and Ovarian (PLCO) Cancer Screening Trial><Prostate, Lung, Colo-rectal and Ovarian Cancer (PLCO) screening trial><Prostate, Lung, Colo-rectal, and Ovarian (PLCO)><Prostate, Lung, Colo-rectal, and Ovarian Cancer Screening Trial><Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial><Prostate, Lung, Colorectal and Ovarian Cancer (PLCO) screening trial><Prostate, Lung, Colorectal, and Ovarian (PLCO)><Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial><Prostate, Lung, Ovarian (PLCO)><Prostatic Gland><Protocol><Protocols documentation><Pulmonary Cancer><Pulmonary malignant Neoplasm><Race><Races><Research><Research Resources><Resources><Reticuloendothelial System, Serum, Plasma><Risk><Sampling><Screening for cancer><Sensitivity and Specificity><Signal Transduction><Signal Transduction Systems><Signaling><Signs and Symptoms><Specificity><Stomach Cancer><Testing><Tissue-Specific Differential Gene Expression><Tissue-Specific Gene Expression><Tissues><Training><Tube><United States><Validation><adenoma><ages><algorithm training><bio-markers><biologic marker><biological signal transduction><biomarker><biomarker discovery><cancer care><cancer classification><cancer diagnosis><cancer statistics><cancer type><cell free DNA><cell free DNA profiling><cell free DNA screening><cell free DNA-based assay><cell free circulating DNA><cell-free DNA assay><cell-free DNA test><cfDNA assay><cfDNA profiling><cfDNA screening><cfDNA test><cfDNA-based assay><clinical diagnosis><colorectal cancer detection><colorectal cancer early detection><colorectal cancer screening><colorectum><detect colorectal cancer><detection test><detection tests><early cancer detection><early detection><epigenetic biomarker><epigenetic marker><epigenetically><faces><facial><gastric malignancy><genome scale><genome wide analysis><genome wide studies><genome-wide><genome-wide analysis><genome-wide identification><genomewide><improved><interest><liver cancer><liver malignancy><lung cancer><machine based learning><machine learning based model><machine learning model><malignancy><malignant liver tumor><malignant stomach neoplasm><malignant stomach tumor><minimally invasive><mortality><nano><neoplasm/cancer><next gen sequencing><next generation sequencing><nextgen sequencing><ovarian cancer><pathway><patient adherence><patient cooperation><pilot study><pre-clinical><preclinical><prospective><prostate, lung, colorectal and ovarian cancer screening cohort><prostate, lung, colorectal, and ovarian cancer screening><racial><racial background><racial origin><screening><screening cancer patients><screening program><screenings><seal><sex><stomach fundus cancer><stomach pylorus cancer><test using cell free DNA><tests using cfDNA><tool><tumor><validations>
View Full Project Details on NIH Reporter
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Wei Zhang

UNIVERSITY OF CHICAGO, CHICAGO, IL

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$676,491
FY 2026

Project Title

A non-invasive blood test for multi-cancer detection and determination of tissue of origin preceding overt cancer diagnosis

Grant Number:

5U01CA297685-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

4/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY In the United States, it is estimated there are ~730,000 new cases of prostate cancer, lung cancer, colorectal cancer (CRC), and ovarian cancer annually. Advances in therapies during the past decades have significantly improved clinical outcomes. For many common cancers, however, tre...

Research Terms

<Address><Age><Algorithms><Assay><Bioassay><Biological Assay><Biological Markers><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Tests><Body Tissues><Brain Cancer><CRC screening><Cancer Control><Cancer Control Science><Cancer Detection><Cancers><Cell Communication and Signaling><Cell Signaling><Clinical><Colon or Rectum><Colorectal><Colorectal Cancer><Communities><DNA><Data><Deoxyribonucleic Acid><Diagnosis><Diagnostic><Diagnostic Findings><Differential Gene Expression><Disease><Disorder><Distant Cancer><Distant Metastasis><Early Diagnosis><Elasticity><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Face><Foundations><Gastric Body Cancer><Gastric Cancer><Gastric Cardia Cancer><Gastric Fundus Cancer><Gastric Pylorus Cancer><Goals><Health><Health Resources><Hematologic Tests><Hematological Tests><Hematology Testing><Heparin><Heparinic Acid><Hepatic Cancer><Individual><Intracellular Communication and Signaling><Knowledge><Lung><Lung Respiratory System><Machine Learning><Malignant Gastric Neoplasm><Malignant Gastric Tumor><Malignant Neoplasms><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Tumor><Malignant Tumor of the Brain><Malignant Tumor of the Lung><Malignant Tumor of the Ovary><Malignant neoplasm of brain><Malignant neoplasm of liver><Malignant neoplasm of lung><Malignant neoplasm of ovary><Malignant neoplasm of prostate><Malignant prostatic tumor><Maps><Medicine><Modeling><NGS Method><NGS system><Outcome><Ovarian><Ovary Cancer><PLCO study><PLCO trial><Pathway interactions><Patient Compliance><Performance><Phase><Pilot Projects><Plasma><Plasma Serum><Pre-Clinical Model><Preclinical Models><Prostate><Prostate CA><Prostate Cancer><Prostate Gland><Prostate malignancy><Prostate, Lung, Colo-rectal and Ovarian (PLCO) Cancer Screening Trial><Prostate, Lung, Colo-rectal and Ovarian Cancer (PLCO) screening trial><Prostate, Lung, Colo-rectal, and Ovarian (PLCO)><Prostate, Lung, Colo-rectal, and Ovarian Cancer Screening Trial><Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial><Prostate, Lung, Colorectal and Ovarian Cancer (PLCO) screening trial><Prostate, Lung, Colorectal, and Ovarian (PLCO)><Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial><Prostate, Lung, Ovarian (PLCO)><Prostatic Gland><Protocol><Protocols documentation><Pulmonary Cancer><Pulmonary malignant Neoplasm><Race><Races><Research><Research Resources><Resources><Reticuloendothelial System, Serum, Plasma><Risk><Sampling><Screening for cancer><Sensitivity and Specificity><Signal Transduction><Signal Transduction Systems><Signaling><Signs and Symptoms><Specificity><Stomach Cancer><Testing><Tissue-Specific Differential Gene Expression><Tissue-Specific Gene Expression><Tissues><Training><Tube><United States><Validation><adenoma><ages><algorithm training><bio-markers><biologic marker><biological signal transduction><biomarker><biomarker discovery><cancer care><cancer classification><cancer diagnosis><cancer statistics><cancer type><cell free DNA><cell free DNA profiling><cell free DNA screening><cell free DNA-based assay><cell free circulating DNA><cell-free DNA assay><cell-free DNA test><cfDNA assay><cfDNA profiling><cfDNA screening><cfDNA test><cfDNA-based assay><clinical diagnosis><colorectal cancer detection><colorectal cancer early detection><colorectal cancer screening><colorectum><detect colorectal cancer><detection test><detection tests><early cancer detection><early detection><epigenetic biomarker><epigenetic marker><epigenetically><faces><facial><gastric malignancy><genome scale><genome wide analysis><genome wide studies><genome-wide><genome-wide analysis><genome-wide identification><genomewide><improved><interest><liver cancer><liver malignancy><lung cancer><machine based learning><machine learning based model><machine learning model><malignancy><malignant liver tumor><malignant stomach neoplasm><malignant stomach tumor><minimally invasive><mortality><nano><neoplasm/cancer><next gen sequencing><next generation sequencing><nextgen sequencing><ovarian cancer><pathway><patient adherence><patient cooperation><pilot study><pre-clinical><preclinical><prospective><prostate, lung, colorectal and ovarian cancer screening cohort><prostate, lung, colorectal, and ovarian cancer screening><racial><racial background><racial origin><screening><screening cancer patients><screening program><screenings><seal><sex><stomach fundus cancer><stomach pylorus cancer><test using cell free DNA><tests using cfDNA><tool><tumor><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Samuel M Wu

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$631,149
FY 2026

Project Title

P30 - Core Grant for Vision Research

Grant Number:

2P30EY002520-46

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/1/1997

End Date:

4/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Overall The objective of the Core Grant for Vision Research is to provide support and facilities, which are not available and cannot be obtained through individual grants, exclusively for vision research and NEI-funded projects at Baylor College of Medicine (BCM). The Core also provides spa...

Research Terms

<2-dimensional><3-D Imaging><3D imaging><Age related macular degeneration><Age-Related Maculopathy><Amblyopia><Animal Model><Animal Models and Related Studies><Animals><Area><Biochemical><Biochemistry><Bioinformatics><Biological Chemistry><Body Tissues><Cell Body><Cells><Chromium><Collaborations><Common Rat Strains><Complex><Computer software><Computers><Confocal Microscopy><Core Facility><Core Grant><Cornea><Cr element><Custom><DNA mutation><Dedications><Developmental Biology><Devices><Discipline><Disease><Disorder><Domestic Rabbit><Dysfunction><Electron Microscope><Electron Microscopy><Electronics><Electrophysiology><Electrophysiology (science)><Eligibility><Eligibility Determination><Environment><Equipment><Equipment Design><Eye><Eyeball><Fluorescence Agents><Fluorescent Agents><Fluorescent Dyes><Fostering><Functional disorder><Funding><Generations><Genes><Genetic Change><Genetic defect><Genetic mutation><Genomics><Glaucoma><Grant><HPLC><High Performance Liquid Chromatography><High Pressure Liquid Chromatography><High Speed Liquid Chromatography><Histologic><Histologically><Histology><Human Resources><Image><Individual><Industrialization><Institution><Investigators><Joints><Label><Laboratory Research><Light Microscope><Manpower><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Mechanics><Medicine><Mice><Mice Mammals><Microscope><Microscopy><Molecular><Molecular Genetics><Murine><Mus><Mutation><NIH><National Institutes of Health><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurophysiology / Electrophysiology><Nucleic Acids><Ophthalmology><Optics><Oryctolagus cuniculus><Paper><Pathogenesis><Phorias><Physiologic><Physiological><Physiopathology><Pigmentary Retinopathy><Postdoc><Postdoctoral Fellow><Process><Productivity><Proteins><Protocol Screening><Psychophysics><Publications><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><Rabbits><Rabbits Mammals><Rat><Rats Mammals><Rattus><Reporting><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Training><Researchers><Resources><Retina><Retinitis Pigmentosa><Scanning><Scientific Publication><Services><Sight><Software><Squint><Strabismus><Structure><Students><Synapses><Synaptic><System><Systems Analyses><Systems Analysis><Tapetoretinal Degeneration><Technology><Thick><Thickness><Three-Dimensional Imaging><Tissue imaging><Tissues><Training><Transmission><United States National Institutes of Health><Vision><Vision research><Visual><Visual System><age dependent macular degeneration><age induced macular degeneration><age related macular disease><age related macular dystrophy><behavior test><behavioral test><college><collegiate><computer imaging><computerized><corneal><customs><design><design and construct><design and construction><designing><digital imaging><electronic><electronic device><electrophysiological><experience><fabrication><flexibility><flexible><fluorescence imaging><fluorescent dye/probe><fluorescent imaging><genome mutation><genome profiling><genomic profiling><glaucomatous><high definition><high-resolution><human genome sequencing><imaging><improved><innovate><innovation><innovative><instrumentation><lens><lenses><mechanic><mechanical><member><model of animal><neural><neuronal><optical><patch clamp><pathophysiology><personnel><post-doc><post-doctoral><post-doctoral trainee><programs><psychophysical><recruit><research associates><research facility><research faculty><rod and cone dystrophy><rod-cone dystrophy><senile macular disease><single cell genomics><sq. ft><square foot><synapse><transmission process><two-dimensional><visual function><visual neuroscience><water maze>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ADAM S KIBEL

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$583,246
FY 2026

Project Title

Polygenic risk stratification combined with mpMRI to identify clinically relevant prostate cancer

Grant Number:

5U01CA268810-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/12/2023

End Date:

3/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Prostate cancer has the highest estimate of heritability of any cancer, with 58% of variability in prostate cancer incidence attributed to inherited genetic factors. Genome wide association studies have validated 269 single nucleotide polymorphisms that are strongly associated with prostate cancer r...

Research Terms

<AI algorithm><AI system><Active Follow-up><Address><Age><Age Years><Algorithms><American male><American man><American men><Armed Forces Personnel><Artificial Intelligence><Biological Markers><Biopsy><Black><Black race><Cancer Cause><Cancer Etiology><Cancers><Caucasian male><Caucasian men><Cessation of life><Clinical><Computer Reasoning><DNA Damage Repair><DNA Repair><Data><Death><Diagnosis><Disease><Disorder><Early Diagnosis><Ensure><Evaluation><Evidence based practice guidelines><GWA study><GWAS><Gene variant><General Population><General Public><Genetic><Genetic Risk><Genotype><Germ Lines><Gleason Grade><Gleason Grade for Prostate Cancer><Gleason Score><Gleason Score for Prostate Cancer><Gleason Sum><Gleason-SC><Goals><Groups at risk><Hereditary><Heritability><Hospitals><Human><Image><Incidence><Inherited><Institution><Knowledge><Lesion><Life><MR Imaging><MR Tomography><MRI><MRI Scans><MRIs><Machine Intelligence><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Malignant Neoplasms><Malignant Tumor><Malignant neoplasm of prostate><Malignant prostatic tumor><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical center><Military><Military Personnel><Modern Man><NCI Organization><NIH><NMR Imaging><NMR Tomography><National Cancer Institute><National Institutes of Health><Nuclear Magnetic Resonance Imaging><Pathway interactions><Patients><People at risk><Persons at risk><Population><Populations at Risk><Predicting Risk><Primary Care><Prophylactic treatment><Prophylaxis><Prospective cohort><Prostate CA><Prostate CA Prevention><Prostate Cancer><Prostate malignancy><Public Health Schools><Research Resources><Resources><Risk><Role><Screening for Prostate Cancer><Serial Magnetic Resonance Imaging><Single Base Polymorphism><Single Nucleotide Polymorphism><Testing><Time><Translating><Translations><U.S. Males><US Men><US male><United States National Institutes of Health><Universities><University Hospitals><Unscheduled DNA Synthesis><Variant><Variation><Woman><Work><Zeugmatography><active followup><age group><age stratification><ages><allelic variant><artificial intelligence algorithm><bio-markers><biobank><biologic marker><biomarker><biorepository><black male><black man><black men><clinical center><clinical practice><clinical relevance><clinical risk><clinical significance><clinically relevant><clinically significant><cohort><deep learning><deep learning method><deep learning strategy><detect prostate cancer><disease risk><disorder risk><disparities in race><disparity due to race><early detection><evidence based guidelines><evidence based recommendations><follow up><follow-up><followed up><followup><forecasting risk><gene repair><gene testing><gene-based testing><genetic information><genetic testing><genetic variant><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic variant><germline genetic screening><germline testing><high risk><high risk men><imaging><improved><inequality due to race><inequity due to race><longitudinal imaging><low-frequency mutation><males in America><males in the U.S.><males in the US><males in the USA><males in the United States><malignancy><man><men><men at high risk><men in America><men in the U.S.><men in the US><men in the USA><men in the United States><military population><mortality><multi-ethnic><multiethnic><neoplasm/cancer><novel><over-treatment><overtreatment><pathway><patient population><polygenetic risk scores><polygenic risk score><population based><precancer><precancerous><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><premalignant><prevent prostate cancer><programs><prospective><prostate cancer detection><prostate cancer early detection><prostate cancer prevention><prostate cancer risk><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><radiologist><rare allele><rare mutation><rare variant><recruit><risk prediction><risk predictions><risk stratification><screening><screenings><serial MRI><serial imaging><single nucleotide variant><social role><stem><stratify risk><tool><translation><trial design><tumor><wasting><white male><white men><whole genome association analysis><whole genome association study>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ADAM J CHICCO

STANFORD UNIVERSITY, STANFORD, CA

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$538,838
FY 2026

Project Title

Development of 3D Multi-cellular Cardiac Tissues for Modeling Delayed Radiation-induced Injury

Grant Number:

1U01AI195484-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2026

End Date:

3/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Accidental exposure to ionizing radiation (IR) poses a significant risk for cardiovascular morbidity, a leading cause of mortality among irradiated populations. However, the mechanisms driving long-term cardiovascular risks remain poorly understood. IR disrupts immune homeostasis, ex...

Research Terms

<3-D><3-Dimensional><3D><AI system><Acceleration><Accidents><Address><Animal Model><Animal Models and Related Studies><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Artificial Intelligence><Assay><Automobile Driving><Autoregulation><Bioassay><Biological Assay><Biological Markers><Blood Serum><Body Tissues><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cancer Survivor><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cas nuclease technology><Cell Body><Cell Reprogramming><Cell-Extracellular Matrix><Cells><Chronic><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Co-culture><Cocultivation><Coculture><Coculture Techniques><Colorado><Computer Reasoning><Culture Media><Data><Data Set><Development><Dose><Drug Screening><Drugs><ECM><Echocardiogram><Echocardiography><Endothelial Cells><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Evaluation><Exposure to><Extracellular Matrix><Female><Fibroblasts><Gamma Radiation><Gamma Rays><Genomics><Groups at risk><Growth Agents><Growth Factor><Growth Substances><Harvest><Health><Heart><Heart Vascular><Histologic><Histologically><Histology><Homeostasis><Hour><Image><Immune><Immune response><Immune system><Immunes><Immunocompetent><Immunologic Model><Immunological Models><In Vitro><In vivo analysis><Inflammaging><Inflammation><Inflammatory><Inflammatory Response><Ionizing Electromagnetic Radiation><Ionizing radiation><Knowledge><Lead><Machine Intelligence><Machine Learning><Macrophage><Medication><Medicinal Chemistry><Metabolic><Mice><Mice Mammals><Modeling><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><Motion><Multiomic Data><Murine><Mus><Mφ><Normal Tissue><Normal tissue morphology><Nutrient><Organ><PBMC><Pathologic><Pathway interactions><Pb element><People at risk><Peripheral Blood Mononuclear Cell><Persons at risk><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Pharmaceutical Preparations><Physiologic><Physiological><Physiological Homeostasis><Physiology><Population><Populations at Risk><Proteins><Proteins Growth Factors><Proteomics><Public Health><RNA Seq><RNA sequencing><RNAseq><Radiation><Radiation Biology><Radiation exposure><Radiation-Ionizing Total><Radiobiology><Reporter><Research><Risk Assessment><Roentgen Rays><Safety><Sampling><Serum><Specificity><Stimulus><System><Tissue Engineering><Tissue Model><Tissues><Transthoracic Echocardiography><Universities><Validation><X-Radiation><X-Ray Radiation><X-ray><Xray><absorption><age-related inflammation><aging associated inflammation><bio-markers><bioengineered tissue><biologic marker><biomarker><biomarker identification><candidate identification><cardiac myocytes differentiated from induced pluripotent stem cell><cardiac tissue engineering><cardiovascular risk><cardiovascular risk factor><cell type><cellular reprogramming><circulatory system><cytokine><determine efficacy><developmental><driving><drug candidate><drug discovery><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><engineered heart tissue><engineered tissue><epigenetically><evaluate efficacy><examine efficacy><experiment><experimental research><experimental study><experiments><functional improvement><genome editing><genomic editing><growth media><heart sonography><heavy metal Pb><heavy metal lead><hiPSC><host response><human iPS><human iPSC><human induced pluripotent cell><human induced pluripotent stem cells><human inducible pluripotent stem cells><human inducible stem cells><human model><human progenitor><human stem cells><iPS><iPS cell derived cardiomyocytes><iPSC><iPSC derived cardiomyocytes><iPSCs><identification of biomarkers><identification of new biomarkers><imaging><immune competent><immune system response><immunoresponse><improve function><improved functional outcomes><in silico><in vivo><in vivo evaluation><in vivo testing><induced human pluripotent stem cells><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cell derived cardiac myocytes><induced pluripotent stem cell derived cardiomyocytes><inducible pluripotent cell><inducible pluripotent stem cell><inducible pluripotent stem cell derived cardiac myocytes><inducible pluripotent stem cells derived cardiomyocytes><inflamm-ageing><inflamm-aging><inflammation associated with aging><innovate><innovation><innovative><ionizing output><irradiation><irradiation-induced injury><machine based learning><male><marker identification><medical countermeasure><model of animal><model of human><molecular profile><molecular signature><mortality><mouse model><multiomics><multiple omic data><multiple omics><murine model><panomics><pathway><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><progenitor biology><progenitor cell biology><radiation countermeasure><radiation mitigation><radiation-induced injury><radiological countermeasure><radiological mitigation><radiomitigation><reconstruction><response><scATAC sequencing><scATAC-seq><scRNA sequencing><scRNA-seq><single cell ATAC-seq><single cell ATAC-sequencing><single cell Assay for Transposase Accessible Chromatin sequencing><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell sequencing assay for transposase accessible chromatin><single cell transcriptomic profiling><single-cell Assay for Transposase-Accessible Chromatin with sequencing><single-cell RNA sequencing><single-cell assay for transposase-accessible chromatin using sequencing><single-cell assay for transposase-accessible chromatin-seq><stem and progenitor biology><stem cell biology><stem cell technology><success><therapeutically effective><three dimensional><tool><transcriptome sequencing><transcriptomic sequencing><validations><γ-Radiation><γ-Ray><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph C. Wu

STANFORD UNIVERSITY, STANFORD, CA

High-opportunity lead · 82/100
Likely hiring
Above-average budget
Very recent
Active award
$538,838
FY 2026

Project Title

Development of 3D Multi-cellular Cardiac Tissues for Modeling Delayed Radiation-induced Injury

Grant Number:

1U01AI195484-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2026

End Date:

3/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Accidental exposure to ionizing radiation (IR) poses a significant risk for cardiovascular morbidity, a leading cause of mortality among irradiated populations. However, the mechanisms driving long-term cardiovascular risks remain poorly understood. IR disrupts immune homeostasis, ex...

Research Terms

<3-D><3-Dimensional><3D><AI system><Acceleration><Accidents><Address><Animal Model><Animal Models and Related Studies><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Artificial Intelligence><Assay><Automobile Driving><Autoregulation><Bioassay><Biological Assay><Biological Markers><Blood Serum><Body Tissues><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cancer Survivor><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cas nuclease technology><Cell Body><Cell Reprogramming><Cell-Extracellular Matrix><Cells><Chronic><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Co-culture><Cocultivation><Coculture><Coculture Techniques><Colorado><Computer Reasoning><Culture Media><Data><Data Set><Development><Dose><Drug Screening><Drugs><ECM><Echocardiogram><Echocardiography><Endothelial Cells><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Evaluation><Exposure to><Extracellular Matrix><Female><Fibroblasts><Gamma Radiation><Gamma Rays><Genomics><Groups at risk><Growth Agents><Growth Factor><Growth Substances><Harvest><Health><Heart><Heart Vascular><Histologic><Histologically><Histology><Homeostasis><Hour><Image><Immune><Immune response><Immune system><Immunes><Immunocompetent><Immunologic Model><Immunological Models><In Vitro><In vivo analysis><Inflammaging><Inflammation><Inflammatory><Inflammatory Response><Ionizing Electromagnetic Radiation><Ionizing radiation><Knowledge><Lead><Machine Intelligence><Machine Learning><Macrophage><Medication><Medicinal Chemistry><Metabolic><Mice><Mice Mammals><Modeling><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><Motion><Multiomic Data><Murine><Mus><Mφ><Normal Tissue><Normal tissue morphology><Nutrient><Organ><PBMC><Pathologic><Pathway interactions><Pb element><People at risk><Peripheral Blood Mononuclear Cell><Persons at risk><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Pharmaceutical Preparations><Physiologic><Physiological><Physiological Homeostasis><Physiology><Population><Populations at Risk><Proteins><Proteins Growth Factors><Proteomics><Public Health><RNA Seq><RNA sequencing><RNAseq><Radiation><Radiation Biology><Radiation exposure><Radiation-Ionizing Total><Radiobiology><Reporter><Research><Risk Assessment><Roentgen Rays><Safety><Sampling><Serum><Specificity><Stimulus><System><Tissue Engineering><Tissue Model><Tissues><Transthoracic Echocardiography><Universities><Validation><X-Radiation><X-Ray Radiation><X-ray><Xray><absorption><age-related inflammation><aging associated inflammation><bio-markers><bioengineered tissue><biologic marker><biomarker><biomarker identification><candidate identification><cardiac myocytes differentiated from induced pluripotent stem cell><cardiac tissue engineering><cardiovascular risk><cardiovascular risk factor><cell type><cellular reprogramming><circulatory system><cytokine><determine efficacy><developmental><driving><drug candidate><drug discovery><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><engineered heart tissue><engineered tissue><epigenetically><evaluate efficacy><examine efficacy><experiment><experimental research><experimental study><experiments><functional improvement><genome editing><genomic editing><growth media><heart sonography><heavy metal Pb><heavy metal lead><hiPSC><host response><human iPS><human iPSC><human induced pluripotent cell><human induced pluripotent stem cells><human inducible pluripotent stem cells><human inducible stem cells><human model><human progenitor><human stem cells><iPS><iPS cell derived cardiomyocytes><iPSC><iPSC derived cardiomyocytes><iPSCs><identification of biomarkers><identification of new biomarkers><imaging><immune competent><immune system response><immunoresponse><improve function><improved functional outcomes><in silico><in vivo><in vivo evaluation><in vivo testing><induced human pluripotent stem cells><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cell derived cardiac myocytes><induced pluripotent stem cell derived cardiomyocytes><inducible pluripotent cell><inducible pluripotent stem cell><inducible pluripotent stem cell derived cardiac myocytes><inducible pluripotent stem cells derived cardiomyocytes><inflamm-ageing><inflamm-aging><inflammation associated with aging><innovate><innovation><innovative><ionizing output><irradiation><irradiation-induced injury><machine based learning><male><marker identification><medical countermeasure><model of animal><model of human><molecular profile><molecular signature><mortality><mouse model><multiomics><multiple omic data><multiple omics><murine model><panomics><pathway><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><progenitor biology><progenitor cell biology><radiation countermeasure><radiation mitigation><radiation-induced injury><radiological countermeasure><radiological mitigation><radiomitigation><reconstruction><response><scATAC sequencing><scATAC-seq><scRNA sequencing><scRNA-seq><single cell ATAC-seq><single cell ATAC-sequencing><single cell Assay for Transposase Accessible Chromatin sequencing><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell sequencing assay for transposase accessible chromatin><single cell transcriptomic profiling><single-cell Assay for Transposase-Accessible Chromatin with sequencing><single-cell RNA sequencing><single-cell assay for transposase-accessible chromatin using sequencing><single-cell assay for transposase-accessible chromatin-seq><stem and progenitor biology><stem cell biology><stem cell technology><success><therapeutically effective><three dimensional><tool><transcriptome sequencing><transcriptomic sequencing><validations><γ-Radiation><γ-Ray><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christos Davatzikos

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

High-opportunity lead · 80/100
Likely hiring
Large award
Recent
Active award
$2,564,449
FY 2026

Project Title

Ultrascale Machine Learning to Empower Discovery in Alzheimer’s Disease Biobanks

Grant Number:

2U01AG068057-06

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2020

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Our U01 renewal application - Artificial Intelligence for Alzheimer's Disease (AI4AD) - expands on four productive themes from our prior funding period, supported by strong empirical results in our recent high impact publications. By developing cutting-edge Artificial Intelligence and Machi...

Research Terms

<A β-42><A β42><A-beta 42><A-beta42><AD and related dementia><AD biological marker><AD biomarker><AD dementia><AD related biomarker><AD related dementia><AD therapy><AD treatment><ADRD><AI Augmented><AI assisted><AI based><AI based model><AI driven><AI enhanced><AI integrated><AI language models><AI model><AI model training><AI powered><AI system><AI training><Abeta-42><Abeta42><Address><Africa><African><African American><Afro American><Afroamerican><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease treatment><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer treatment><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease therapy><Alzheimer's related biomarker><Alzheimer's therapy><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Amyloid beta-42><Amyloid beta42><Amyloid β-42><Amyloid β42><Amyloidβ-42><Amyloidβ42><Artificial Intelligence><Artificial Intelligence enhanced><Artificial intelligence model training><Asian Americans><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autopsy><Aβ-42><Aβ42><Base Pairing><Benchmarking><Best Practice Analysis><Bioinformatics><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain scan><Cell Line><CellLine><Cerebral Amyloid Angiopathy><Classification><Clinical><Clinical Trials Design><Cognitive><Communication><Computer Reasoning><Congophilic Angiopathy><ConvNet><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Bases><Data Set><Databases><Dementia><Diagnosis><Diagnostic><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Dimensions><Disease Progression><Drops><Drug usage><Drugs><Educational workshop><Encephalon><Ensure><European ancestry><Family><Funding><Future><GWA study><GWAS><Genes><Genetic><Genome><Genomics><Heterogeneity><Human><Image><India><Inflammatory><Korea><Koreans><Language><Latin American><Lewy Bodies><Link><MR Imaging><MR Tomography><MRI><MRIs><MT-bound tau><Machine Intelligence><Machine Learning><Magnetic Resonance Imaging><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Memory><Methods><Modeling><Modern Man><Molecular><NMR Imaging><NMR Tomography><Nature><Nerve Degeneration><Neuron Degeneration><Nuclear Magnetic Resonance Imaging><Onset of illness><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathology><Patients><Pattern><Persons><Pharmaceutical Preparations><Phenotype><Plasma><Plasma Serum><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Precision therapeutics><Primary Senile Degenerative Dementia><Process><Productivity><Publications><Rad.-PET><Research><Reticuloendothelial System, Serum, Plasma><Risk><Running><Sampling><Scanning><Scientific Publication><Selection for Treatments><Slide><Strains Cell Lines><System><Systematics><TAR DNA-binding protein 43><TDP-43><TDP43><Technology><Testing><Training><Transformer language model><Treatment Efficacy><Validation><Visuospatial><Work><Workshop><Zeugmatography><ages><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence language models><artificial intelligence model><artificial intelligence powered><artificial intelligence training><artificial intelligence-based model><benchmark><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biorepository><brain tissue><cerebrovascular amyloidosis><clinical diagnosis><clinical predictors><clinical prognosis><cohort><compound repositioning><compound repurposing><conference><convention><convolutional network><convolutional neural nets><convolutional neural network><cultured cell line><dMRI><data base><data diversity><deep learning><deep learning method><deep learning strategy><depository><diffusion tensor imaging><discover genes><disease classification><disease onset><disorder classification><disorder onset><diverse data><diverse populations><drug discovery><drug repositioning><drug repurposing><drug use><drug/agent><empowerment><endophenotype><enhanced with AI><enhanced with Artificial Intelligence><entire genome><executive control><executive function><expression subtypes><full genome><gene discovery><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic biomarker><genomic data><genomic dataset><genomic marker><genomic signature><health determinants><healthy aging><healthy human aging><heterogeneous population><iPS><iPSC><iPSCs><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><in vivo><indexing><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><intervention efficacy><large language model><large scale language model><machine based learning><massive scale language models><microtubule bound tau><microtubule-bound tau><molecular sub-types><molecular subsets><molecular subtypes><necropsy><neural degeneration><neural imaging><neuro-imaging><neurodegeneration><neurodegenerative><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><new therapeutic uses for existing drugs><new use of drug><new uses for an approved drug><new uses for existing drugs><news><nosology><novel><older adult><older adulthood><optimal therapies><optimal treatments><p-tau><p-τ><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><personalization of treatment><personalized diagnosis><personalized diagnostics><personalized medicine><personalized therapy><personalized treatment><pharmacological repurposing><phospho-tau><phospho-τ><phosphorylated tau><polygenetic risk scores><polygenic risk score><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><post-translational modification of tau><postmortem><posttranslational modification of tau><precise diagnostics><precision diagnostics><precision medicine><precision therapies><precision treatment><precision-based medicine><primary degenerative dementia><prognosis model><prognostic><prognostic method><prognostic model><prognostication method><programs><protein TDP-43><protein TDP43><repositioning approved drugs><repositioning existing drugs><repository><repurpose approved drugs><repurpose approved medication><repurpose approved therapeutic><repurpose existing drugs><repurpose existing medication><repurpose existing medicine><repurpose existing therapeutics><repurpose existing therapies><repurpose medicine><repurposing a drug><repurposing agent><repurposing candidates><repurposing established drugs><repurposing established medication><repurposing existing pharmacological agents><repurposing medication><repurposing of already existing drugs><repurposing pharmaceuticals><response to therapy><response to treatment><selection of treatment><senile dementia of the Alzheimer type><social><success><summit><symposia><symposium><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><therapeutic efficacy><therapeutic repositioning><therapeutic repurposing><therapeutic response><therapeutic target><therapy efficacy><therapy response><therapy selection><tool><treatment response><treatment responsiveness><treatment selection><validations><vascular><visual spatial><web site><website><whole genome><whole genome association analysis><whole genome association study><τ Proteins><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Heng Huang

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

High-opportunity lead · 80/100
Likely hiring
Large award
Recent
Active award
$2,564,449
FY 2026

Project Title

Ultrascale Machine Learning to Empower Discovery in Alzheimer’s Disease Biobanks

Grant Number:

2U01AG068057-06

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2020

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Our U01 renewal application - Artificial Intelligence for Alzheimer's Disease (AI4AD) - expands on four productive themes from our prior funding period, supported by strong empirical results in our recent high impact publications. By developing cutting-edge Artificial Intelligence and Machi...

Research Terms

<A β-42><A β42><A-beta 42><A-beta42><AD and related dementia><AD biological marker><AD biomarker><AD dementia><AD related biomarker><AD related dementia><AD therapy><AD treatment><ADRD><AI Augmented><AI assisted><AI based><AI based model><AI driven><AI enhanced><AI integrated><AI language models><AI model><AI model training><AI powered><AI system><AI training><Abeta-42><Abeta42><Address><Africa><African><African American><Afro American><Afroamerican><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease treatment><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer treatment><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease therapy><Alzheimer's related biomarker><Alzheimer's therapy><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Amyloid beta-42><Amyloid beta42><Amyloid β-42><Amyloid β42><Amyloidβ-42><Amyloidβ42><Artificial Intelligence><Artificial Intelligence enhanced><Artificial intelligence model training><Asian Americans><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autopsy><Aβ-42><Aβ42><Base Pairing><Benchmarking><Best Practice Analysis><Bioinformatics><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain scan><Cell Line><CellLine><Cerebral Amyloid Angiopathy><Classification><Clinical><Clinical Trials Design><Cognitive><Communication><Computer Reasoning><Congophilic Angiopathy><ConvNet><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Bases><Data Set><Databases><Dementia><Diagnosis><Diagnostic><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Dimensions><Disease Progression><Drops><Drug usage><Drugs><Educational workshop><Encephalon><Ensure><European ancestry><Family><Funding><Future><GWA study><GWAS><Genes><Genetic><Genome><Genomics><Heterogeneity><Human><Image><India><Inflammatory><Korea><Koreans><Language><Latin American><Lewy Bodies><Link><MR Imaging><MR Tomography><MRI><MRIs><MT-bound tau><Machine Intelligence><Machine Learning><Magnetic Resonance Imaging><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Memory><Methods><Modeling><Modern Man><Molecular><NMR Imaging><NMR Tomography><Nature><Nerve Degeneration><Neuron Degeneration><Nuclear Magnetic Resonance Imaging><Onset of illness><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathology><Patients><Pattern><Persons><Pharmaceutical Preparations><Phenotype><Plasma><Plasma Serum><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Precision therapeutics><Primary Senile Degenerative Dementia><Process><Productivity><Publications><Rad.-PET><Research><Reticuloendothelial System, Serum, Plasma><Risk><Running><Sampling><Scanning><Scientific Publication><Selection for Treatments><Slide><Strains Cell Lines><System><Systematics><TAR DNA-binding protein 43><TDP-43><TDP43><Technology><Testing><Training><Transformer language model><Treatment Efficacy><Validation><Visuospatial><Work><Workshop><Zeugmatography><ages><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence language models><artificial intelligence model><artificial intelligence powered><artificial intelligence training><artificial intelligence-based model><benchmark><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biorepository><brain tissue><cerebrovascular amyloidosis><clinical diagnosis><clinical predictors><clinical prognosis><cohort><compound repositioning><compound repurposing><conference><convention><convolutional network><convolutional neural nets><convolutional neural network><cultured cell line><dMRI><data base><data diversity><deep learning><deep learning method><deep learning strategy><depository><diffusion tensor imaging><discover genes><disease classification><disease onset><disorder classification><disorder onset><diverse data><diverse populations><drug discovery><drug repositioning><drug repurposing><drug use><drug/agent><empowerment><endophenotype><enhanced with AI><enhanced with Artificial Intelligence><entire genome><executive control><executive function><expression subtypes><full genome><gene discovery><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic biomarker><genomic data><genomic dataset><genomic marker><genomic signature><health determinants><healthy aging><healthy human aging><heterogeneous population><iPS><iPSC><iPSCs><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><in vivo><indexing><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><intervention efficacy><large language model><large scale language model><machine based learning><massive scale language models><microtubule bound tau><microtubule-bound tau><molecular sub-types><molecular subsets><molecular subtypes><necropsy><neural degeneration><neural imaging><neuro-imaging><neurodegeneration><neurodegenerative><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><new therapeutic uses for existing drugs><new use of drug><new uses for an approved drug><new uses for existing drugs><news><nosology><novel><older adult><older adulthood><optimal therapies><optimal treatments><p-tau><p-τ><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><personalization of treatment><personalized diagnosis><personalized diagnostics><personalized medicine><personalized therapy><personalized treatment><pharmacological repurposing><phospho-tau><phospho-τ><phosphorylated tau><polygenetic risk scores><polygenic risk score><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><post-translational modification of tau><postmortem><posttranslational modification of tau><precise diagnostics><precision diagnostics><precision medicine><precision therapies><precision treatment><precision-based medicine><primary degenerative dementia><prognosis model><prognostic><prognostic method><prognostic model><prognostication method><programs><protein TDP-43><protein TDP43><repositioning approved drugs><repositioning existing drugs><repository><repurpose approved drugs><repurpose approved medication><repurpose approved therapeutic><repurpose existing drugs><repurpose existing medication><repurpose existing medicine><repurpose existing therapeutics><repurpose existing therapies><repurpose medicine><repurposing a drug><repurposing agent><repurposing candidates><repurposing established drugs><repurposing established medication><repurposing existing pharmacological agents><repurposing medication><repurposing of already existing drugs><repurposing pharmaceuticals><response to therapy><response to treatment><selection of treatment><senile dementia of the Alzheimer type><social><success><summit><symposia><symposium><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><therapeutic efficacy><therapeutic repositioning><therapeutic repurposing><therapeutic response><therapeutic target><therapy efficacy><therapy response><therapy selection><tool><treatment response><treatment responsiveness><treatment selection><validations><vascular><visual spatial><web site><website><whole genome><whole genome association analysis><whole genome association study><τ Proteins><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gyungah Jun

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

High-opportunity lead · 80/100
Likely hiring
Large award
Recent
Active award
$2,564,449
FY 2026

Project Title

Ultrascale Machine Learning to Empower Discovery in Alzheimer’s Disease Biobanks

Grant Number:

2U01AG068057-06

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2020

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Our U01 renewal application - Artificial Intelligence for Alzheimer's Disease (AI4AD) - expands on four productive themes from our prior funding period, supported by strong empirical results in our recent high impact publications. By developing cutting-edge Artificial Intelligence and Machi...

Research Terms

<A β-42><A β42><A-beta 42><A-beta42><AD and related dementia><AD biological marker><AD biomarker><AD dementia><AD related biomarker><AD related dementia><AD therapy><AD treatment><ADRD><AI Augmented><AI assisted><AI based><AI based model><AI driven><AI enhanced><AI integrated><AI language models><AI model><AI model training><AI powered><AI system><AI training><Abeta-42><Abeta42><Address><Africa><African><African American><Afro American><Afroamerican><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease treatment><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer treatment><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease therapy><Alzheimer's related biomarker><Alzheimer's therapy><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Amyloid beta-42><Amyloid beta42><Amyloid β-42><Amyloid β42><Amyloidβ-42><Amyloidβ42><Artificial Intelligence><Artificial Intelligence enhanced><Artificial intelligence model training><Asian Americans><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autopsy><Aβ-42><Aβ42><Base Pairing><Benchmarking><Best Practice Analysis><Bioinformatics><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain scan><Cell Line><CellLine><Cerebral Amyloid Angiopathy><Classification><Clinical><Clinical Trials Design><Cognitive><Communication><Computer Reasoning><Congophilic Angiopathy><ConvNet><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Bases><Data Set><Databases><Dementia><Diagnosis><Diagnostic><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Dimensions><Disease Progression><Drops><Drug usage><Drugs><Educational workshop><Encephalon><Ensure><European ancestry><Family><Funding><Future><GWA study><GWAS><Genes><Genetic><Genome><Genomics><Heterogeneity><Human><Image><India><Inflammatory><Korea><Koreans><Language><Latin American><Lewy Bodies><Link><MR Imaging><MR Tomography><MRI><MRIs><MT-bound tau><Machine Intelligence><Machine Learning><Magnetic Resonance Imaging><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Memory><Methods><Modeling><Modern Man><Molecular><NMR Imaging><NMR Tomography><Nature><Nerve Degeneration><Neuron Degeneration><Nuclear Magnetic Resonance Imaging><Onset of illness><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathology><Patients><Pattern><Persons><Pharmaceutical Preparations><Phenotype><Plasma><Plasma Serum><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Precision therapeutics><Primary Senile Degenerative Dementia><Process><Productivity><Publications><Rad.-PET><Research><Reticuloendothelial System, Serum, Plasma><Risk><Running><Sampling><Scanning><Scientific Publication><Selection for Treatments><Slide><Strains Cell Lines><System><Systematics><TAR DNA-binding protein 43><TDP-43><TDP43><Technology><Testing><Training><Transformer language model><Treatment Efficacy><Validation><Visuospatial><Work><Workshop><Zeugmatography><ages><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence language models><artificial intelligence model><artificial intelligence powered><artificial intelligence training><artificial intelligence-based model><benchmark><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biorepository><brain tissue><cerebrovascular amyloidosis><clinical diagnosis><clinical predictors><clinical prognosis><cohort><compound repositioning><compound repurposing><conference><convention><convolutional network><convolutional neural nets><convolutional neural network><cultured cell line><dMRI><data base><data diversity><deep learning><deep learning method><deep learning strategy><depository><diffusion tensor imaging><discover genes><disease classification><disease onset><disorder classification><disorder onset><diverse data><diverse populations><drug discovery><drug repositioning><drug repurposing><drug use><drug/agent><empowerment><endophenotype><enhanced with AI><enhanced with Artificial Intelligence><entire genome><executive control><executive function><expression subtypes><full genome><gene discovery><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic biomarker><genomic data><genomic dataset><genomic marker><genomic signature><health determinants><healthy aging><healthy human aging><heterogeneous population><iPS><iPSC><iPSCs><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><in vivo><indexing><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><intervention efficacy><large language model><large scale language model><machine based learning><massive scale language models><microtubule bound tau><microtubule-bound tau><molecular sub-types><molecular subsets><molecular subtypes><necropsy><neural degeneration><neural imaging><neuro-imaging><neurodegeneration><neurodegenerative><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><new therapeutic uses for existing drugs><new use of drug><new uses for an approved drug><new uses for existing drugs><news><nosology><novel><older adult><older adulthood><optimal therapies><optimal treatments><p-tau><p-τ><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><personalization of treatment><personalized diagnosis><personalized diagnostics><personalized medicine><personalized therapy><personalized treatment><pharmacological repurposing><phospho-tau><phospho-τ><phosphorylated tau><polygenetic risk scores><polygenic risk score><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><post-translational modification of tau><postmortem><posttranslational modification of tau><precise diagnostics><precision diagnostics><precision medicine><precision therapies><precision treatment><precision-based medicine><primary degenerative dementia><prognosis model><prognostic><prognostic method><prognostic model><prognostication method><programs><protein TDP-43><protein TDP43><repositioning approved drugs><repositioning existing drugs><repository><repurpose approved drugs><repurpose approved medication><repurpose approved therapeutic><repurpose existing drugs><repurpose existing medication><repurpose existing medicine><repurpose existing therapeutics><repurpose existing therapies><repurpose medicine><repurposing a drug><repurposing agent><repurposing candidates><repurposing established drugs><repurposing established medication><repurposing existing pharmacological agents><repurposing medication><repurposing of already existing drugs><repurposing pharmaceuticals><response to therapy><response to treatment><selection of treatment><senile dementia of the Alzheimer type><social><success><summit><symposia><symposium><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><therapeutic efficacy><therapeutic repositioning><therapeutic repurposing><therapeutic response><therapeutic target><therapy efficacy><therapy response><therapy selection><tool><treatment response><treatment responsiveness><treatment selection><validations><vascular><visual spatial><web site><website><whole genome><whole genome association analysis><whole genome association study><τ Proteins><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ANDREW J SAYKIN

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

High-opportunity lead · 80/100
Likely hiring
Large award
Recent
Active award
$2,564,449
FY 2026

Project Title

Ultrascale Machine Learning to Empower Discovery in Alzheimer’s Disease Biobanks

Grant Number:

2U01AG068057-06

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2020

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Our U01 renewal application - Artificial Intelligence for Alzheimer's Disease (AI4AD) - expands on four productive themes from our prior funding period, supported by strong empirical results in our recent high impact publications. By developing cutting-edge Artificial Intelligence and Machi...

Research Terms

<A β-42><A β42><A-beta 42><A-beta42><AD and related dementia><AD biological marker><AD biomarker><AD dementia><AD related biomarker><AD related dementia><AD therapy><AD treatment><ADRD><AI Augmented><AI assisted><AI based><AI based model><AI driven><AI enhanced><AI integrated><AI language models><AI model><AI model training><AI powered><AI system><AI training><Abeta-42><Abeta42><Address><Africa><African><African American><Afro American><Afroamerican><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease treatment><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer treatment><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease therapy><Alzheimer's related biomarker><Alzheimer's therapy><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Amyloid beta-42><Amyloid beta42><Amyloid β-42><Amyloid β42><Amyloidβ-42><Amyloidβ42><Artificial Intelligence><Artificial Intelligence enhanced><Artificial intelligence model training><Asian Americans><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autopsy><Aβ-42><Aβ42><Base Pairing><Benchmarking><Best Practice Analysis><Bioinformatics><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain scan><Cell Line><CellLine><Cerebral Amyloid Angiopathy><Classification><Clinical><Clinical Trials Design><Cognitive><Communication><Computer Reasoning><Congophilic Angiopathy><ConvNet><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Bases><Data Set><Databases><Dementia><Diagnosis><Diagnostic><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Dimensions><Disease Progression><Drops><Drug usage><Drugs><Educational workshop><Encephalon><Ensure><European ancestry><Family><Funding><Future><GWA study><GWAS><Genes><Genetic><Genome><Genomics><Heterogeneity><Human><Image><India><Inflammatory><Korea><Koreans><Language><Latin American><Lewy Bodies><Link><MR Imaging><MR Tomography><MRI><MRIs><MT-bound tau><Machine Intelligence><Machine Learning><Magnetic Resonance Imaging><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Memory><Methods><Modeling><Modern Man><Molecular><NMR Imaging><NMR Tomography><Nature><Nerve Degeneration><Neuron Degeneration><Nuclear Magnetic Resonance Imaging><Onset of illness><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathology><Patients><Pattern><Persons><Pharmaceutical Preparations><Phenotype><Plasma><Plasma Serum><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Precision therapeutics><Primary Senile Degenerative Dementia><Process><Productivity><Publications><Rad.-PET><Research><Reticuloendothelial System, Serum, Plasma><Risk><Running><Sampling><Scanning><Scientific Publication><Selection for Treatments><Slide><Strains Cell Lines><System><Systematics><TAR DNA-binding protein 43><TDP-43><TDP43><Technology><Testing><Training><Transformer language model><Treatment Efficacy><Validation><Visuospatial><Work><Workshop><Zeugmatography><ages><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence language models><artificial intelligence model><artificial intelligence powered><artificial intelligence training><artificial intelligence-based model><benchmark><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biorepository><brain tissue><cerebrovascular amyloidosis><clinical diagnosis><clinical predictors><clinical prognosis><cohort><compound repositioning><compound repurposing><conference><convention><convolutional network><convolutional neural nets><convolutional neural network><cultured cell line><dMRI><data base><data diversity><deep learning><deep learning method><deep learning strategy><depository><diffusion tensor imaging><discover genes><disease classification><disease onset><disorder classification><disorder onset><diverse data><diverse populations><drug discovery><drug repositioning><drug repurposing><drug use><drug/agent><empowerment><endophenotype><enhanced with AI><enhanced with Artificial Intelligence><entire genome><executive control><executive function><expression subtypes><full genome><gene discovery><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic biomarker><genomic data><genomic dataset><genomic marker><genomic signature><health determinants><healthy aging><healthy human aging><heterogeneous population><iPS><iPSC><iPSCs><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><in vivo><indexing><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><intervention efficacy><large language model><large scale language model><machine based learning><massive scale language models><microtubule bound tau><microtubule-bound tau><molecular sub-types><molecular subsets><molecular subtypes><necropsy><neural degeneration><neural imaging><neuro-imaging><neurodegeneration><neurodegenerative><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><new therapeutic uses for existing drugs><new use of drug><new uses for an approved drug><new uses for existing drugs><news><nosology><novel><older adult><older adulthood><optimal therapies><optimal treatments><p-tau><p-τ><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><personalization of treatment><personalized diagnosis><personalized diagnostics><personalized medicine><personalized therapy><personalized treatment><pharmacological repurposing><phospho-tau><phospho-τ><phosphorylated tau><polygenetic risk scores><polygenic risk score><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><post-translational modification of tau><postmortem><posttranslational modification of tau><precise diagnostics><precision diagnostics><precision medicine><precision therapies><precision treatment><precision-based medicine><primary degenerative dementia><prognosis model><prognostic><prognostic method><prognostic model><prognostication method><programs><protein TDP-43><protein TDP43><repositioning approved drugs><repositioning existing drugs><repository><repurpose approved drugs><repurpose approved medication><repurpose approved therapeutic><repurpose existing drugs><repurpose existing medication><repurpose existing medicine><repurpose existing therapeutics><repurpose existing therapies><repurpose medicine><repurposing a drug><repurposing agent><repurposing candidates><repurposing established drugs><repurposing established medication><repurposing existing pharmacological agents><repurposing medication><repurposing of already existing drugs><repurposing pharmaceuticals><response to therapy><response to treatment><selection of treatment><senile dementia of the Alzheimer type><social><success><summit><symposia><symposium><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><therapeutic efficacy><therapeutic repositioning><therapeutic repurposing><therapeutic response><therapeutic target><therapy efficacy><therapy response><therapy selection><tool><treatment response><treatment responsiveness><treatment selection><validations><vascular><visual spatial><web site><website><whole genome><whole genome association analysis><whole genome association study><τ Proteins><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LI SHEN

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

High-opportunity lead · 80/100
Likely hiring
Large award
Recent
Active award
$2,564,449
FY 2026

Project Title

Ultrascale Machine Learning to Empower Discovery in Alzheimer’s Disease Biobanks

Grant Number:

2U01AG068057-06

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2020

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Our U01 renewal application - Artificial Intelligence for Alzheimer's Disease (AI4AD) - expands on four productive themes from our prior funding period, supported by strong empirical results in our recent high impact publications. By developing cutting-edge Artificial Intelligence and Machi...

Research Terms

<A β-42><A β42><A-beta 42><A-beta42><AD and related dementia><AD biological marker><AD biomarker><AD dementia><AD related biomarker><AD related dementia><AD therapy><AD treatment><ADRD><AI Augmented><AI assisted><AI based><AI based model><AI driven><AI enhanced><AI integrated><AI language models><AI model><AI model training><AI powered><AI system><AI training><Abeta-42><Abeta42><Address><Africa><African><African American><Afro American><Afroamerican><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease treatment><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer treatment><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease therapy><Alzheimer's related biomarker><Alzheimer's therapy><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Amyloid beta-42><Amyloid beta42><Amyloid β-42><Amyloid β42><Amyloidβ-42><Amyloidβ42><Artificial Intelligence><Artificial Intelligence enhanced><Artificial intelligence model training><Asian Americans><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autopsy><Aβ-42><Aβ42><Base Pairing><Benchmarking><Best Practice Analysis><Bioinformatics><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain scan><Cell Line><CellLine><Cerebral Amyloid Angiopathy><Classification><Clinical><Clinical Trials Design><Cognitive><Communication><Computer Reasoning><Congophilic Angiopathy><ConvNet><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Bases><Data Set><Databases><Dementia><Diagnosis><Diagnostic><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Dimensions><Disease Progression><Drops><Drug usage><Drugs><Educational workshop><Encephalon><Ensure><European ancestry><Family><Funding><Future><GWA study><GWAS><Genes><Genetic><Genome><Genomics><Heterogeneity><Human><Image><India><Inflammatory><Korea><Koreans><Language><Latin American><Lewy Bodies><Link><MR Imaging><MR Tomography><MRI><MRIs><MT-bound tau><Machine Intelligence><Machine Learning><Magnetic Resonance Imaging><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Memory><Methods><Modeling><Modern Man><Molecular><NMR Imaging><NMR Tomography><Nature><Nerve Degeneration><Neuron Degeneration><Nuclear Magnetic Resonance Imaging><Onset of illness><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathology><Patients><Pattern><Persons><Pharmaceutical Preparations><Phenotype><Plasma><Plasma Serum><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Precision therapeutics><Primary Senile Degenerative Dementia><Process><Productivity><Publications><Rad.-PET><Research><Reticuloendothelial System, Serum, Plasma><Risk><Running><Sampling><Scanning><Scientific Publication><Selection for Treatments><Slide><Strains Cell Lines><System><Systematics><TAR DNA-binding protein 43><TDP-43><TDP43><Technology><Testing><Training><Transformer language model><Treatment Efficacy><Validation><Visuospatial><Work><Workshop><Zeugmatography><ages><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence language models><artificial intelligence model><artificial intelligence powered><artificial intelligence training><artificial intelligence-based model><benchmark><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biorepository><brain tissue><cerebrovascular amyloidosis><clinical diagnosis><clinical predictors><clinical prognosis><cohort><compound repositioning><compound repurposing><conference><convention><convolutional network><convolutional neural nets><convolutional neural network><cultured cell line><dMRI><data base><data diversity><deep learning><deep learning method><deep learning strategy><depository><diffusion tensor imaging><discover genes><disease classification><disease onset><disorder classification><disorder onset><diverse data><diverse populations><drug discovery><drug repositioning><drug repurposing><drug use><drug/agent><empowerment><endophenotype><enhanced with AI><enhanced with Artificial Intelligence><entire genome><executive control><executive function><expression subtypes><full genome><gene discovery><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic biomarker><genomic data><genomic dataset><genomic marker><genomic signature><health determinants><healthy aging><healthy human aging><heterogeneous population><iPS><iPSC><iPSCs><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><in vivo><indexing><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><intervention efficacy><large language model><large scale language model><machine based learning><massive scale language models><microtubule bound tau><microtubule-bound tau><molecular sub-types><molecular subsets><molecular subtypes><necropsy><neural degeneration><neural imaging><neuro-imaging><neurodegeneration><neurodegenerative><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><new therapeutic uses for existing drugs><new use of drug><new uses for an approved drug><new uses for existing drugs><news><nosology><novel><older adult><older adulthood><optimal therapies><optimal treatments><p-tau><p-τ><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><personalization of treatment><personalized diagnosis><personalized diagnostics><personalized medicine><personalized therapy><personalized treatment><pharmacological repurposing><phospho-tau><phospho-τ><phosphorylated tau><polygenetic risk scores><polygenic risk score><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><post-translational modification of tau><postmortem><posttranslational modification of tau><precise diagnostics><precision diagnostics><precision medicine><precision therapies><precision treatment><precision-based medicine><primary degenerative dementia><prognosis model><prognostic><prognostic method><prognostic model><prognostication method><programs><protein TDP-43><protein TDP43><repositioning approved drugs><repositioning existing drugs><repository><repurpose approved drugs><repurpose approved medication><repurpose approved therapeutic><repurpose existing drugs><repurpose existing medication><repurpose existing medicine><repurpose existing therapeutics><repurpose existing therapies><repurpose medicine><repurposing a drug><repurposing agent><repurposing candidates><repurposing established drugs><repurposing established medication><repurposing existing pharmacological agents><repurposing medication><repurposing of already existing drugs><repurposing pharmaceuticals><response to therapy><response to treatment><selection of treatment><senile dementia of the Alzheimer type><social><success><summit><symposia><symposium><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><therapeutic efficacy><therapeutic repositioning><therapeutic repurposing><therapeutic response><therapeutic target><therapy efficacy><therapy response><therapy selection><tool><treatment response><treatment responsiveness><treatment selection><validations><vascular><visual spatial><web site><website><whole genome><whole genome association analysis><whole genome association study><τ Proteins><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PAUL M THOMPSON

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

High-opportunity lead · 80/100
Likely hiring
Large award
Recent
Active award
$2,564,449
FY 2026

Project Title

Ultrascale Machine Learning to Empower Discovery in Alzheimer’s Disease Biobanks

Grant Number:

2U01AG068057-06

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2020

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Our U01 renewal application - Artificial Intelligence for Alzheimer's Disease (AI4AD) - expands on four productive themes from our prior funding period, supported by strong empirical results in our recent high impact publications. By developing cutting-edge Artificial Intelligence and Machi...

Research Terms

<A β-42><A β42><A-beta 42><A-beta42><AD and related dementia><AD biological marker><AD biomarker><AD dementia><AD related biomarker><AD related dementia><AD therapy><AD treatment><ADRD><AI Augmented><AI assisted><AI based><AI based model><AI driven><AI enhanced><AI integrated><AI language models><AI model><AI model training><AI powered><AI system><AI training><Abeta-42><Abeta42><Address><Africa><African><African American><Afro American><Afroamerican><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease treatment><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer treatment><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease therapy><Alzheimer's related biomarker><Alzheimer's therapy><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Amyloid beta-42><Amyloid beta42><Amyloid β-42><Amyloid β42><Amyloidβ-42><Amyloidβ42><Artificial Intelligence><Artificial Intelligence enhanced><Artificial intelligence model training><Asian Americans><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autopsy><Aβ-42><Aβ42><Base Pairing><Benchmarking><Best Practice Analysis><Bioinformatics><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain scan><Cell Line><CellLine><Cerebral Amyloid Angiopathy><Classification><Clinical><Clinical Trials Design><Cognitive><Communication><Computer Reasoning><Congophilic Angiopathy><ConvNet><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Bases><Data Set><Databases><Dementia><Diagnosis><Diagnostic><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Dimensions><Disease Progression><Drops><Drug usage><Drugs><Educational workshop><Encephalon><Ensure><European ancestry><Family><Funding><Future><GWA study><GWAS><Genes><Genetic><Genome><Genomics><Heterogeneity><Human><Image><India><Inflammatory><Korea><Koreans><Language><Latin American><Lewy Bodies><Link><MR Imaging><MR Tomography><MRI><MRIs><MT-bound tau><Machine Intelligence><Machine Learning><Magnetic Resonance Imaging><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Memory><Methods><Modeling><Modern Man><Molecular><NMR Imaging><NMR Tomography><Nature><Nerve Degeneration><Neuron Degeneration><Nuclear Magnetic Resonance Imaging><Onset of illness><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathology><Patients><Pattern><Persons><Pharmaceutical Preparations><Phenotype><Plasma><Plasma Serum><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Precision therapeutics><Primary Senile Degenerative Dementia><Process><Productivity><Publications><Rad.-PET><Research><Reticuloendothelial System, Serum, Plasma><Risk><Running><Sampling><Scanning><Scientific Publication><Selection for Treatments><Slide><Strains Cell Lines><System><Systematics><TAR DNA-binding protein 43><TDP-43><TDP43><Technology><Testing><Training><Transformer language model><Treatment Efficacy><Validation><Visuospatial><Work><Workshop><Zeugmatography><ages><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence language models><artificial intelligence model><artificial intelligence powered><artificial intelligence training><artificial intelligence-based model><benchmark><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biorepository><brain tissue><cerebrovascular amyloidosis><clinical diagnosis><clinical predictors><clinical prognosis><cohort><compound repositioning><compound repurposing><conference><convention><convolutional network><convolutional neural nets><convolutional neural network><cultured cell line><dMRI><data base><data diversity><deep learning><deep learning method><deep learning strategy><depository><diffusion tensor imaging><discover genes><disease classification><disease onset><disorder classification><disorder onset><diverse data><diverse populations><drug discovery><drug repositioning><drug repurposing><drug use><drug/agent><empowerment><endophenotype><enhanced with AI><enhanced with Artificial Intelligence><entire genome><executive control><executive function><expression subtypes><full genome><gene discovery><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic biomarker><genomic data><genomic dataset><genomic marker><genomic signature><health determinants><healthy aging><healthy human aging><heterogeneous population><iPS><iPSC><iPSCs><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><in vivo><indexing><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><intervention efficacy><large language model><large scale language model><machine based learning><massive scale language models><microtubule bound tau><microtubule-bound tau><molecular sub-types><molecular subsets><molecular subtypes><necropsy><neural degeneration><neural imaging><neuro-imaging><neurodegeneration><neurodegenerative><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><new therapeutic uses for existing drugs><new use of drug><new uses for an approved drug><new uses for existing drugs><news><nosology><novel><older adult><older adulthood><optimal therapies><optimal treatments><p-tau><p-τ><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><personalization of treatment><personalized diagnosis><personalized diagnostics><personalized medicine><personalized therapy><personalized treatment><pharmacological repurposing><phospho-tau><phospho-τ><phosphorylated tau><polygenetic risk scores><polygenic risk score><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><post-translational modification of tau><postmortem><posttranslational modification of tau><precise diagnostics><precision diagnostics><precision medicine><precision therapies><precision treatment><precision-based medicine><primary degenerative dementia><prognosis model><prognostic><prognostic method><prognostic model><prognostication method><programs><protein TDP-43><protein TDP43><repositioning approved drugs><repositioning existing drugs><repository><repurpose approved drugs><repurpose approved medication><repurpose approved therapeutic><repurpose existing drugs><repurpose existing medication><repurpose existing medicine><repurpose existing therapeutics><repurpose existing therapies><repurpose medicine><repurposing a drug><repurposing agent><repurposing candidates><repurposing established drugs><repurposing established medication><repurposing existing pharmacological agents><repurposing medication><repurposing of already existing drugs><repurposing pharmaceuticals><response to therapy><response to treatment><selection of treatment><senile dementia of the Alzheimer type><social><success><summit><symposia><symposium><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><therapeutic efficacy><therapeutic repositioning><therapeutic repurposing><therapeutic response><therapeutic target><therapy efficacy><therapy response><therapy selection><tool><treatment response><treatment responsiveness><treatment selection><validations><vascular><visual spatial><web site><website><whole genome><whole genome association analysis><whole genome association study><τ Proteins><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Duygu Tosun-Turgut

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

High-opportunity lead · 80/100
Likely hiring
Large award
Recent
Active award
$2,564,449
FY 2026

Project Title

Ultrascale Machine Learning to Empower Discovery in Alzheimer’s Disease Biobanks

Grant Number:

2U01AG068057-06

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2020

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Our U01 renewal application - Artificial Intelligence for Alzheimer's Disease (AI4AD) - expands on four productive themes from our prior funding period, supported by strong empirical results in our recent high impact publications. By developing cutting-edge Artificial Intelligence and Machi...

Research Terms

<A β-42><A β42><A-beta 42><A-beta42><AD and related dementia><AD biological marker><AD biomarker><AD dementia><AD related biomarker><AD related dementia><AD therapy><AD treatment><ADRD><AI Augmented><AI assisted><AI based><AI based model><AI driven><AI enhanced><AI integrated><AI language models><AI model><AI model training><AI powered><AI system><AI training><Abeta-42><Abeta42><Address><Africa><African><African American><Afro American><Afroamerican><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease treatment><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer treatment><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease biological marker><Alzheimer's disease biomarker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related biomarker><Alzheimer's disease related dementia><Alzheimer's disease therapy><Alzheimer's related biomarker><Alzheimer's therapy><Alzheimers Dementia><Alzheimer’s biological marker><Amentia><Amyloid><Amyloid Substance><Amyloid beta-42><Amyloid beta42><Amyloid β-42><Amyloid β42><Amyloidβ-42><Amyloidβ42><Artificial Intelligence><Artificial Intelligence enhanced><Artificial intelligence model training><Asian Americans><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autopsy><Aβ-42><Aβ42><Base Pairing><Benchmarking><Best Practice Analysis><Bioinformatics><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain scan><Cell Line><CellLine><Cerebral Amyloid Angiopathy><Classification><Clinical><Clinical Trials Design><Cognitive><Communication><Computer Reasoning><Congophilic Angiopathy><ConvNet><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Bases><Data Set><Databases><Dementia><Diagnosis><Diagnostic><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Dimensions><Disease Progression><Drops><Drug usage><Drugs><Educational workshop><Encephalon><Ensure><European ancestry><Family><Funding><Future><GWA study><GWAS><Genes><Genetic><Genome><Genomics><Heterogeneity><Human><Image><India><Inflammatory><Korea><Koreans><Language><Latin American><Lewy Bodies><Link><MR Imaging><MR Tomography><MRI><MRIs><MT-bound tau><Machine Intelligence><Machine Learning><Magnetic Resonance Imaging><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Memory><Methods><Modeling><Modern Man><Molecular><NMR Imaging><NMR Tomography><Nature><Nerve Degeneration><Neuron Degeneration><Nuclear Magnetic Resonance Imaging><Onset of illness><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathology><Patients><Pattern><Persons><Pharmaceutical Preparations><Phenotype><Plasma><Plasma Serum><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Precision therapeutics><Primary Senile Degenerative Dementia><Process><Productivity><Publications><Rad.-PET><Research><Reticuloendothelial System, Serum, Plasma><Risk><Running><Sampling><Scanning><Scientific Publication><Selection for Treatments><Slide><Strains Cell Lines><System><Systematics><TAR DNA-binding protein 43><TDP-43><TDP43><Technology><Testing><Training><Transformer language model><Treatment Efficacy><Validation><Visuospatial><Work><Workshop><Zeugmatography><ages><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence language models><artificial intelligence model><artificial intelligence powered><artificial intelligence training><artificial intelligence-based model><benchmark><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker in AD><biomarker in Alzheimer's><biomarker in Alzheimer's disease><biorepository><brain tissue><cerebrovascular amyloidosis><clinical diagnosis><clinical predictors><clinical prognosis><cohort><compound repositioning><compound repurposing><conference><convention><convolutional network><convolutional neural nets><convolutional neural network><cultured cell line><dMRI><data base><data diversity><deep learning><deep learning method><deep learning strategy><depository><diffusion tensor imaging><discover genes><disease classification><disease onset><disorder classification><disorder onset><diverse data><diverse populations><drug discovery><drug repositioning><drug repurposing><drug use><drug/agent><empowerment><endophenotype><enhanced with AI><enhanced with Artificial Intelligence><entire genome><executive control><executive function><expression subtypes><full genome><gene discovery><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic biomarker><genomic data><genomic dataset><genomic marker><genomic signature><health determinants><healthy aging><healthy human aging><heterogeneous population><iPS><iPSC><iPSCs><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><in vivo><indexing><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><intervention efficacy><large language model><large scale language model><machine based learning><massive scale language models><microtubule bound tau><microtubule-bound tau><molecular sub-types><molecular subsets><molecular subtypes><necropsy><neural degeneration><neural imaging><neuro-imaging><neurodegeneration><neurodegenerative><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><new therapeutic uses for existing drugs><new use of drug><new uses for an approved drug><new uses for existing drugs><news><nosology><novel><older adult><older adulthood><optimal therapies><optimal treatments><p-tau><p-τ><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><personalization of treatment><personalized diagnosis><personalized diagnostics><personalized medicine><personalized therapy><personalized treatment><pharmacological repurposing><phospho-tau><phospho-τ><phosphorylated tau><polygenetic risk scores><polygenic risk score><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><post-translational modification of tau><postmortem><posttranslational modification of tau><precise diagnostics><precision diagnostics><precision medicine><precision therapies><precision treatment><precision-based medicine><primary degenerative dementia><prognosis model><prognostic><prognostic method><prognostic model><prognostication method><programs><protein TDP-43><protein TDP43><repositioning approved drugs><repositioning existing drugs><repository><repurpose approved drugs><repurpose approved medication><repurpose approved therapeutic><repurpose existing drugs><repurpose existing medication><repurpose existing medicine><repurpose existing therapeutics><repurpose existing therapies><repurpose medicine><repurposing a drug><repurposing agent><repurposing candidates><repurposing established drugs><repurposing established medication><repurposing existing pharmacological agents><repurposing medication><repurposing of already existing drugs><repurposing pharmaceuticals><response to therapy><response to treatment><selection of treatment><senile dementia of the Alzheimer type><social><success><summit><symposia><symposium><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><therapeutic efficacy><therapeutic repositioning><therapeutic repurposing><therapeutic response><therapeutic target><therapy efficacy><therapy response><therapy selection><tool><treatment response><treatment responsiveness><treatment selection><validations><vascular><visual spatial><web site><website><whole genome><whole genome association analysis><whole genome association study><τ Proteins><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tony Yuen

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

High-opportunity lead · 74/100
Likely hiring
Large award
Active award
Team-scale grant
$2,321,095
FY 2026

Project Title

A Humanized Monoclonal FSH Blocking Antibody for Alzheimer's Disease

Grant Number:

3U01AG073148-05S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY Thanks to the ongoing parent U01 AG073148, we are currently moving our humanized follicle–stimulating hormone– (FSH–) blocking antibody, Hu6, through early phase development for future use not only in Alzheimer’s disease (AD), but also in osteoporosis, obesity, and dyslipidemia. The...

Research Terms

<3xTg><3xTg-AD mice><3xTg-AD mouse><AD dementia><AD model><AD pathology><APP-PS1><APP/PS1><Ab response><Acceleration><Acute><Admission><Admission activity><Adverse effects><African Green Monkey><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's disease model><Alzheimer's disease pathology><Alzheimer's pathology><Alzheimers Dementia><Amentia><Ammon Horn><Antibodies><Antibody Formation><Antibody Production><Antigenic Determinants><Binding><Binding Determinants><Biodistribution><Bioreactors><Blocking Antibodies><Blood><Blood Chemical Analyses><Blood Chemical Analysis><Blood Reticuloendothelial System><Blood Serum><Body fat><Bypass><Cell Line><Cell Therapy><CellLine><Cercopithecus aethiops><Chlorocebus aethiops><Cholesterol><Clinical><Clinical Research><Clinical Study><Code><Coding System><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complex><Computer Models><Computerized Models><Contracting Opportunities><Contracts><Cornu Ammonis><Data><Dementia><Dentate Fascia><Development><Disease><Disorder><Disturbance in cognition><Dose><Drug Kinetics><Dyslipidemias><Energy Expenditure><Energy Metabolism><Entorhinal Area><Epitopes><Estrogen Replacement Therapy><Estrogens><FSH Receptors><Fascia Dentata><Fees><Follicle Stimulating Hormone><Follicle Stimulating Hormone Receptor><Follitropin><Food and Drug Administration><Formulation><Funding><Future><Generations><Goals><Gonadal structure><Good Manufacturing Process><Good manufacturing practice><Grivet Monkey><Gyrus Dentatus><Health Hazards><Hippocampus><Hormone use><Human><Hypercholesteremia><Hypophysis><Hypophysis Cerebri><IND Filing><IND application><IND package><IND submission><Impaired cognition><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Laboratories><Lead><Life><Mammalia><Mammals><Medical><Memory Loss><Menopause><Mice><Mice Mammals><Modern Man><Molecular Interaction><Monkeys><Murine><Mus><Nerve Degeneration><Neuron Degeneration><Obesity><Oophorectomy><Organ><Osteoporosis><Ovariectomy><Parents><Pathogenesis><Pb element><Perimenopausal><Perimenopause><Persons><Pharmacokinetics><Phase><Physiology><Pituitary><Pituitary Gland><Pituitary Hormones><Pituitary Nervous System><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Primary Senile Degenerative Dementia><Process><Public Health><Receptor Protein><Recombinant TSH><Recombinant Thyroid-Stimulating Hormone><Regulation><Rest><Risk><Running><Safety><Scientist><Serum><Severities><Strains Cell Lines><Structure><Symptom Burden><Testing><Textbooks><Therapeutic><Therapeutic Estrogen><Therapeutic antibodies><Thyreotropin><Thyroid><Thyroid Gland><Thyroid Head and Neck><Thyroid Stimulating Hormone><Thyroid-Stimulating Hormone><Thyrotropin><Time><Toxicology><Transgenic Organisms><USFDA><United States Food and Drug Administration><VAC-TX><Vaccine Therapy><Visceral><Woman><Work><adiposity><after menopause><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging associated disease><aging associated disorders><aging population><aging related disease><aging related disorders><alzheimer model><antibody biosynthesis><blood chemistry><bone><bone loss><cell bank><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular therapeutic><cellular therapy><clinic ready><clinical ready><cognitive dysfunction><cognitive loss><commercialization><computational modeling><computational models><computer based models><computerized modeling><corpulence><cultured cell line><dentate gyrus><design><designing><developmental><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><efficacy study><entorhinal cortex><experience><female gonadectomy><first in man><first-in-human><following menopause><gender difference><gender-associated difference><gonad><gonads><good laboratory practice><heavy metal Pb><heavy metal lead><high blood cholesterol><hippocampal><humanized monoclonal antibodies><hypercholesterolemia><immunoglobulin biosynthesis><knock-down><knockdown><manufacture><manufacturing organization><memory decline><men><menopause transition><microbioreactor><mild cognitive decline><mild cognitive disorder><mild cognitive dysfunction><mild cognitive impairment><mild cognitive loss><mild neurocognitive impairment><monomer><mouse model><murine model><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neuronal degeneration><parent><past menopause><peri-menopausal><peri-menopause><pharmacologic><population aging><post-menopausal><postmenopausal><postmenopausal status><prevent><preventing><primary degenerative dementia><programs><quality assurance><receptor><senile dementia of the Alzheimer type><shRNA><short hairpin RNA><small hairpin RNA><stable cell line><therapeutic candidate><therapeutic vaccination><transgenic><transition to menopause><transitional menopause>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mone Zaidi

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

High-opportunity lead · 74/100
Likely hiring
Large award
Active award
Team-scale grant
$2,321,095
FY 2026

Project Title

A Humanized Monoclonal FSH Blocking Antibody for Alzheimer's Disease

Grant Number:

3U01AG073148-05S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY Thanks to the ongoing parent U01 AG073148, we are currently moving our humanized follicle–stimulating hormone– (FSH–) blocking antibody, Hu6, through early phase development for future use not only in Alzheimer’s disease (AD), but also in osteoporosis, obesity, and dyslipidemia. The...

Research Terms

<3xTg><3xTg-AD mice><3xTg-AD mouse><AD dementia><AD model><AD pathology><APP-PS1><APP/PS1><Ab response><Acceleration><Acute><Admission><Admission activity><Adverse effects><African Green Monkey><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's disease model><Alzheimer's disease pathology><Alzheimer's pathology><Alzheimers Dementia><Amentia><Ammon Horn><Antibodies><Antibody Formation><Antibody Production><Antigenic Determinants><Binding><Binding Determinants><Biodistribution><Bioreactors><Blocking Antibodies><Blood><Blood Chemical Analyses><Blood Chemical Analysis><Blood Reticuloendothelial System><Blood Serum><Body fat><Bypass><Cell Line><Cell Therapy><CellLine><Cercopithecus aethiops><Chlorocebus aethiops><Cholesterol><Clinical><Clinical Research><Clinical Study><Code><Coding System><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complex><Computer Models><Computerized Models><Contracting Opportunities><Contracts><Cornu Ammonis><Data><Dementia><Dentate Fascia><Development><Disease><Disorder><Disturbance in cognition><Dose><Drug Kinetics><Dyslipidemias><Energy Expenditure><Energy Metabolism><Entorhinal Area><Epitopes><Estrogen Replacement Therapy><Estrogens><FSH Receptors><Fascia Dentata><Fees><Follicle Stimulating Hormone><Follicle Stimulating Hormone Receptor><Follitropin><Food and Drug Administration><Formulation><Funding><Future><Generations><Goals><Gonadal structure><Good Manufacturing Process><Good manufacturing practice><Grivet Monkey><Gyrus Dentatus><Health Hazards><Hippocampus><Hormone use><Human><Hypercholesteremia><Hypophysis><Hypophysis Cerebri><IND Filing><IND application><IND package><IND submission><Impaired cognition><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Laboratories><Lead><Life><Mammalia><Mammals><Medical><Memory Loss><Menopause><Mice><Mice Mammals><Modern Man><Molecular Interaction><Monkeys><Murine><Mus><Nerve Degeneration><Neuron Degeneration><Obesity><Oophorectomy><Organ><Osteoporosis><Ovariectomy><Parents><Pathogenesis><Pb element><Perimenopausal><Perimenopause><Persons><Pharmacokinetics><Phase><Physiology><Pituitary><Pituitary Gland><Pituitary Hormones><Pituitary Nervous System><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Primary Senile Degenerative Dementia><Process><Public Health><Receptor Protein><Recombinant TSH><Recombinant Thyroid-Stimulating Hormone><Regulation><Rest><Risk><Running><Safety><Scientist><Serum><Severities><Strains Cell Lines><Structure><Symptom Burden><Testing><Textbooks><Therapeutic><Therapeutic Estrogen><Therapeutic antibodies><Thyreotropin><Thyroid><Thyroid Gland><Thyroid Head and Neck><Thyroid Stimulating Hormone><Thyroid-Stimulating Hormone><Thyrotropin><Time><Toxicology><Transgenic Organisms><USFDA><United States Food and Drug Administration><VAC-TX><Vaccine Therapy><Visceral><Woman><Work><adiposity><after menopause><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging associated disease><aging associated disorders><aging population><aging related disease><aging related disorders><alzheimer model><antibody biosynthesis><blood chemistry><bone><bone loss><cell bank><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular therapeutic><cellular therapy><clinic ready><clinical ready><cognitive dysfunction><cognitive loss><commercialization><computational modeling><computational models><computer based models><computerized modeling><corpulence><cultured cell line><dentate gyrus><design><designing><developmental><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><efficacy study><entorhinal cortex><experience><female gonadectomy><first in man><first-in-human><following menopause><gender difference><gender-associated difference><gonad><gonads><good laboratory practice><heavy metal Pb><heavy metal lead><high blood cholesterol><hippocampal><humanized monoclonal antibodies><hypercholesterolemia><immunoglobulin biosynthesis><knock-down><knockdown><manufacture><manufacturing organization><memory decline><men><menopause transition><microbioreactor><mild cognitive decline><mild cognitive disorder><mild cognitive dysfunction><mild cognitive impairment><mild cognitive loss><mild neurocognitive impairment><monomer><mouse model><murine model><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neuronal degeneration><parent><past menopause><peri-menopausal><peri-menopause><pharmacologic><population aging><post-menopausal><postmenopausal><postmenopausal status><prevent><preventing><primary degenerative dementia><programs><quality assurance><receptor><senile dementia of the Alzheimer type><shRNA><short hairpin RNA><small hairpin RNA><stable cell line><therapeutic candidate><therapeutic vaccination><transgenic><transition to menopause><transitional menopause>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sean C Murphy

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

High-opportunity lead · 74/100
Likely hiring
Large award
Active award
Team-scale grant
$1,028,550
FY 2026

Project Title

Integrating human and non-human primate data to understand the acquisition of pre-erythrocytic immunity in the face of previous malaria exposure

Grant Number:

5U01AI165457-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/10/2022

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Pre-erythrocytic (PE) malaria vaccines that completely prevent infection in malaria non-endemic regions have often failed to achieve equally high-level protection when tested in endemic regions. Data from animal models and humans has identified certain factors that may be contributing to th...

Research Terms

<15 year old><15 years of age><Acute><Address><Affect><Africa South of the Sahara><Animal Model><Animal Models and Related Studies><Animals><Area><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood erythrocyte><Blood specimen><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cell Body><Cells><Chronic><Clinical><Clinical Trials><Complex><Data><Disease><Disorder><Erythrocytes><Erythrocytic><Europe><Exhibits><Goals><Human><Immune><Immune Evasion><Immune Markers><Immune response><Immune system><Immunes><Immunity><Immunization><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunologic Model><Immunological><Immunological Models><Immunologically><Immunologics><Immunology><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Incidence><Individual><Infection><Infection prevention><Inflammation><Inflammatory><Innate Immune Response><Innate Immunity><Laboratories><Liver><Long-term infection><M mulatta><M nemestrina><M. mulatta><M. nemestrina><Macaca mulatta><Macaca nemestrina><Macaca rhesus><Malaria><Malaria Vaccines><Malarial Vaccines><Maps><Marrow erythrocyte><Measures><Modeling><Modern Man><NHP models><Native Immunity><Natural Immunity><Non-Specific Immunity><Nonspecific Immunity><Paludism><Parasitemia><Parasites><Pattern><Performance><Peripheral><Persons><Pigtail Macaque><Pigtail Monkey><Plasmodium><Plasmodium Infections><Prevent infection><Primates><Primates Mammals><Publishing><Red Blood Cells><Red Cell><Research Resources><Resources><Rhesus Macaque><Rhesus Monkey><Sampling><Scientist><Site><Sporozoites><Sub-Saharan Africa><Subsaharan Africa><Symptoms><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><Testing><Tissue Sample><Tissues><Transmission><Vaccinated><Vaccination><Vaccines><acute infection><adaptive immune response><adaptive immunity><age 15><age 15 years><animal data><base><bases><bio-markers><biologic marker><biomarker><blood corpuscles><chronic infection><circumsporozoite protein><clinical trial participant><cs protein><density><design><designing><disease control><disorder control><efficacy trial><experience><exposed human population><fifteen year old><fifteen years of age><hepatic body system><hepatic organ system><host response><human data><human exposure><immune evasive><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immune-based biomarkers><immunogenicity><immunologic reactivity control><immunological biomarkers><immunological markers><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive response><insight><inter-institutional><malaria infection><malaria-infected><malarial infection><model building><model of animal><mouse model><murine model><non-human primate><nonhuman primate><nonhuman primate models><novel><parasaetemia><peripheral blood><persistent infection><pig-tailed macaque><resident memory T cell><response><thymus derived lymphocyte><tissue resident memory T cell><transmission process><vaccination study><vaccination trial><vaccine candidate><vaccine efficacy><vaccine study><vaccine trial><vaccines against malaria><volunteer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Brandon Keith Wilder

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

High-opportunity lead · 74/100
Likely hiring
Large award
Active award
Team-scale grant
$1,028,550
FY 2026

Project Title

Integrating human and non-human primate data to understand the acquisition of pre-erythrocytic immunity in the face of previous malaria exposure

Grant Number:

5U01AI165457-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/10/2022

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Pre-erythrocytic (PE) malaria vaccines that completely prevent infection in malaria non-endemic regions have often failed to achieve equally high-level protection when tested in endemic regions. Data from animal models and humans has identified certain factors that may be contributing to th...

Research Terms

<15 year old><15 years of age><Acute><Address><Affect><Africa South of the Sahara><Animal Model><Animal Models and Related Studies><Animals><Area><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood erythrocyte><Blood specimen><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cell Body><Cells><Chronic><Clinical><Clinical Trials><Complex><Data><Disease><Disorder><Erythrocytes><Erythrocytic><Europe><Exhibits><Goals><Human><Immune><Immune Evasion><Immune Markers><Immune response><Immune system><Immunes><Immunity><Immunization><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunologic Model><Immunological><Immunological Models><Immunologically><Immunologics><Immunology><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Incidence><Individual><Infection><Infection prevention><Inflammation><Inflammatory><Innate Immune Response><Innate Immunity><Laboratories><Liver><Long-term infection><M mulatta><M nemestrina><M. mulatta><M. nemestrina><Macaca mulatta><Macaca nemestrina><Macaca rhesus><Malaria><Malaria Vaccines><Malarial Vaccines><Maps><Marrow erythrocyte><Measures><Modeling><Modern Man><NHP models><Native Immunity><Natural Immunity><Non-Specific Immunity><Nonspecific Immunity><Paludism><Parasitemia><Parasites><Pattern><Performance><Peripheral><Persons><Pigtail Macaque><Pigtail Monkey><Plasmodium><Plasmodium Infections><Prevent infection><Primates><Primates Mammals><Publishing><Red Blood Cells><Red Cell><Research Resources><Resources><Rhesus Macaque><Rhesus Monkey><Sampling><Scientist><Site><Sporozoites><Sub-Saharan Africa><Subsaharan Africa><Symptoms><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><Testing><Tissue Sample><Tissues><Transmission><Vaccinated><Vaccination><Vaccines><acute infection><adaptive immune response><adaptive immunity><age 15><age 15 years><animal data><base><bases><bio-markers><biologic marker><biomarker><blood corpuscles><chronic infection><circumsporozoite protein><clinical trial participant><cs protein><density><design><designing><disease control><disorder control><efficacy trial><experience><exposed human population><fifteen year old><fifteen years of age><hepatic body system><hepatic organ system><host response><human data><human exposure><immune evasive><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immune-based biomarkers><immunogenicity><immunologic reactivity control><immunological biomarkers><immunological markers><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive response><insight><inter-institutional><malaria infection><malaria-infected><malarial infection><model building><model of animal><mouse model><murine model><non-human primate><nonhuman primate><nonhuman primate models><novel><parasaetemia><peripheral blood><persistent infection><pig-tailed macaque><resident memory T cell><response><thymus derived lymphocyte><tissue resident memory T cell><transmission process><vaccination study><vaccination trial><vaccine candidate><vaccine efficacy><vaccine study><vaccine trial><vaccines against malaria><volunteer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOHN Walter GLOD

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Recent
Active award
$636,527
FY 2026

Project Title

National Succinate Dehydrogenase-deficient GIST Translational Research and Clinical Trial Consortium

Grant Number:

5U01CA278470-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Gastrointestinal stromal tumor (GIST) is often effectively treated with FDA-approved first-line therapies such as imatinib and avapritinib. However, this strategy is ineffective in a particular subset of GIST patients—those with a GIST caused by inherited loss-of-function mu...

Research Terms

<21+ years old><APO2 Ligand><Address><Adolescent and Young Adult><Adult><Adult Human><Advocate><Agonist><Alkylating Agents><Alkylators><Apo-2 Ligand><Apoptosis><Apoptosis Pathway><Assay><Ayvakit><Basic Research><Basic Science><Binding><Bioassay><Biological Assay><Biological Markers><Biology><Biopsy><Blood Sample><Blood specimen><Body Tissues><Cancers><Care Givers><Caregivers><Cell Body><Cell Survival><Cell Viability><Cells><Cessation of life><Childhood><Citric Acid Cycle><Clinical><Clinical Sciences><Clinical Trials><Combined Modality Therapy><Complex><Cultured Neoplastic Cells><Cultured Tumor Cells><Cytotoxic TRAIL Receptor-2><DNA Damage Repair><DNA Double Strand Break><DNA Repair><DNA strand break><DR5><DR5 protein><Data><Data Set><Death><Death Receptor 5><Development><Digestive Stromal Neoplasm><Digestive Stromal Tumor><Disease><Disease Progression><Disorder><Disparate><ER stress><EXTMR><Enrollment><Exhibits><Extramural><Extramural Activities><FDA approved><Familial Gangliocytic Paraganglioma><Familial Paraganglioma><Family><Family member><Fas-Like Protein Precursor><Financial Support><Fumarate Reductase><Gastrointestinal Autonomic Nerve Tumor><Gastrointestinal Stromal Neoplasms><Gastrointestinal Stromal Tumors><Gene Transcription><Generalized Growth><Generations><Genes><Genetic><Genetic Diseases><Genetic Transcription><Genomic approach><Germ-Line Mutation><Goals><Growth><Hereditary><Hereditary Gangliocytic Paraganglioma><Hereditary Mutation><Hereditary Paraganglioma><Heritability><Heterogeneity><Hypermethylation><Image><Imatinib><In Vitro><Indolent><Induction of Apoptosis><Inherited><Inter-tumoral heterogeneity><Intratumoral heterogeneity><Investigators><KILLER/DR5><Krebs Cycle><Laboratory Research><Lead><Life><Lytotoxicity><Malignant Neoplasms><Malignant Tumor><Medical><Medical Oncology><Metabolic><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Modeling><Molecular><Molecular Interaction><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-site clinical trial><Multicenter clinical trial><Multimodal Therapy><Multimodal Treatment><Multisite clinical trial><NIH><National Institutes of Health><Neoplasm Metastasis><Outcome><PTK Inhibitors><Pathogenicity><Pathway interactions><Patient Care><Patient Care Delivery><Patients><Pb element><Personal Satisfaction><Phase 1/2 Clinical Trial><Phase 2 Clinical Trials><Phase I/II Clinical Trial><Phase II Clinical Trials><Phenotype><Pre-Clinical Model><Preclinical Models><Preclinical data><Prediction of Response to Therapy><Prognosis><Prognostic Marker><Programmed Cell Death><Progressive Disease><Protein Tyrosine Kinase Inhibitors><Pyruvate><RNA Expression><Receptor Protein><Reporting><Research Personnel><Research Resources><Researchers><Resected><Resources><Risk><Safety><Secondary Neoplasm><Secondary Tumor><Succinate Dehydrogenase><Succinates><Succinic Dehydrogenase><Succinic Oxidase><Surgical Oncology><Syndrome><TCA cycle><TK Inhibitors><TNF-Related Apoptosis Inducing Ligand TRAIL><TNF-related apoptosis-inducing ligand><TNFRSF10B><TNFRSF10B gene><TNFSF10 Protein><TRAIL Protein><TRAIL Receptor 2><TRAIL-R2><TRAILR2><TRICK2><TRICK2A><TRICK2B><TRICKB><Temodal><Temodar><Testing><Therapeutic><Tissue Growth><Tissues><Transcription><Translational Research><Translational Science><Treatment outcome><Tricarboxylic Acid Cycle><Tumor Biology><Tumor Cell><Tumor Necrosis Factor Ligand Superfamily Member 10><Tumor Necrosis Factor Receptor-Like Protein ZTNFR9><Tumor Subtype><Tyrosine Kinase Inhibitor><United States National Institutes of Health><Unscheduled DNA Synthesis><Validation><Youth><Youth 10-21><ZTNFR9><adulthood><avapritinib><bio-markers><biobank><biologic marker><biomarker><biorepository><cancer metastasis><cancer type><care for patients><care of patients><caring for patients><clinical center><cohort><combination therapy><combinatorial><combined modality treatment><combined treatment><cytotoxicity><determine efficacy><developmental><digestive tract stromal neoplasm><digestive tract stromal tumor><disease control><disease risk><disorder control><disorder risk><drug sensitivity><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><endoplasmic reticulum stress><enroll><epigenetic gene silencing><epigenetic silencing><evaluate efficacy><examine efficacy><financial aid><financial assistance><fumarate hydrogenase><gastrointestinal tract stromal neoplasm><gastrointestinal tract stromal tumor><genetic condition><genetic disorder><genomic effort><genomic strategy><germ-line defect><germline variant><heavy metal Pb><heavy metal lead><heterogeneity in tumors><homologous recombination><imaging><imaging spectroscopy><improved><industrial partnership><industry partner><industry partnership><innovate><innovation><innovative><insight><intertumoral heterogeneity><intra-tumoral heterogeneity><intratumor heterogeneity><loss of function mutation><malignancy><methazolastone><multi-modal therapy><multi-modal treatment><multiomics><multiple omics><neoplasm/cancer><neoplastic cell><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutics><novel therapy><objective response rate><oncologic surgery><ontogeny><panomics><pathway><patient advocacy group><pediatric><phase 2 trial><phase II protocol><phase II trial><preclinical findings><preclinical information><predict therapeutic response><predict therapy response><prognostic biomarker><prognostic indicator><prognostication><promoter><promotor><receptor><response><spectroscopic imaging><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><temozolomide><therapeutically effective><therapy prediction><tool><transcriptomics><translation research><translational investigation><translational investigator><translational researcher><translational scientist><treatment prediction><treatment response prediction><treatment strategy><tumor><tumor cell metastasis><tumor heterogeneity><unclassified variant><validations><variant of uncertain clinical significance><variant of uncertain significance><variant of undetermined significance><variant of unknown significance><well-being><wellbeing><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jason Keith Sicklick

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Recent
Active award
$636,527
FY 2026

Project Title

National Succinate Dehydrogenase-deficient GIST Translational Research and Clinical Trial Consortium

Grant Number:

5U01CA278470-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Gastrointestinal stromal tumor (GIST) is often effectively treated with FDA-approved first-line therapies such as imatinib and avapritinib. However, this strategy is ineffective in a particular subset of GIST patients—those with a GIST caused by inherited loss-of-function mu...

Research Terms

<21+ years old><APO2 Ligand><Address><Adolescent and Young Adult><Adult><Adult Human><Advocate><Agonist><Alkylating Agents><Alkylators><Apo-2 Ligand><Apoptosis><Apoptosis Pathway><Assay><Ayvakit><Basic Research><Basic Science><Binding><Bioassay><Biological Assay><Biological Markers><Biology><Biopsy><Blood Sample><Blood specimen><Body Tissues><Cancers><Care Givers><Caregivers><Cell Body><Cell Survival><Cell Viability><Cells><Cessation of life><Childhood><Citric Acid Cycle><Clinical><Clinical Sciences><Clinical Trials><Combined Modality Therapy><Complex><Cultured Neoplastic Cells><Cultured Tumor Cells><Cytotoxic TRAIL Receptor-2><DNA Damage Repair><DNA Double Strand Break><DNA Repair><DNA strand break><DR5><DR5 protein><Data><Data Set><Death><Death Receptor 5><Development><Digestive Stromal Neoplasm><Digestive Stromal Tumor><Disease><Disease Progression><Disorder><Disparate><ER stress><EXTMR><Enrollment><Exhibits><Extramural><Extramural Activities><FDA approved><Familial Gangliocytic Paraganglioma><Familial Paraganglioma><Family><Family member><Fas-Like Protein Precursor><Financial Support><Fumarate Reductase><Gastrointestinal Autonomic Nerve Tumor><Gastrointestinal Stromal Neoplasms><Gastrointestinal Stromal Tumors><Gene Transcription><Generalized Growth><Generations><Genes><Genetic><Genetic Diseases><Genetic Transcription><Genomic approach><Germ-Line Mutation><Goals><Growth><Hereditary><Hereditary Gangliocytic Paraganglioma><Hereditary Mutation><Hereditary Paraganglioma><Heritability><Heterogeneity><Hypermethylation><Image><Imatinib><In Vitro><Indolent><Induction of Apoptosis><Inherited><Inter-tumoral heterogeneity><Intratumoral heterogeneity><Investigators><KILLER/DR5><Krebs Cycle><Laboratory Research><Lead><Life><Lytotoxicity><Malignant Neoplasms><Malignant Tumor><Medical><Medical Oncology><Metabolic><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Modeling><Molecular><Molecular Interaction><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-site clinical trial><Multicenter clinical trial><Multimodal Therapy><Multimodal Treatment><Multisite clinical trial><NIH><National Institutes of Health><Neoplasm Metastasis><Outcome><PTK Inhibitors><Pathogenicity><Pathway interactions><Patient Care><Patient Care Delivery><Patients><Pb element><Personal Satisfaction><Phase 1/2 Clinical Trial><Phase 2 Clinical Trials><Phase I/II Clinical Trial><Phase II Clinical Trials><Phenotype><Pre-Clinical Model><Preclinical Models><Preclinical data><Prediction of Response to Therapy><Prognosis><Prognostic Marker><Programmed Cell Death><Progressive Disease><Protein Tyrosine Kinase Inhibitors><Pyruvate><RNA Expression><Receptor Protein><Reporting><Research Personnel><Research Resources><Researchers><Resected><Resources><Risk><Safety><Secondary Neoplasm><Secondary Tumor><Succinate Dehydrogenase><Succinates><Succinic Dehydrogenase><Succinic Oxidase><Surgical Oncology><Syndrome><TCA cycle><TK Inhibitors><TNF-Related Apoptosis Inducing Ligand TRAIL><TNF-related apoptosis-inducing ligand><TNFRSF10B><TNFRSF10B gene><TNFSF10 Protein><TRAIL Protein><TRAIL Receptor 2><TRAIL-R2><TRAILR2><TRICK2><TRICK2A><TRICK2B><TRICKB><Temodal><Temodar><Testing><Therapeutic><Tissue Growth><Tissues><Transcription><Translational Research><Translational Science><Treatment outcome><Tricarboxylic Acid Cycle><Tumor Biology><Tumor Cell><Tumor Necrosis Factor Ligand Superfamily Member 10><Tumor Necrosis Factor Receptor-Like Protein ZTNFR9><Tumor Subtype><Tyrosine Kinase Inhibitor><United States National Institutes of Health><Unscheduled DNA Synthesis><Validation><Youth><Youth 10-21><ZTNFR9><adulthood><avapritinib><bio-markers><biobank><biologic marker><biomarker><biorepository><cancer metastasis><cancer type><care for patients><care of patients><caring for patients><clinical center><cohort><combination therapy><combinatorial><combined modality treatment><combined treatment><cytotoxicity><determine efficacy><developmental><digestive tract stromal neoplasm><digestive tract stromal tumor><disease control><disease risk><disorder control><disorder risk><drug sensitivity><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><endoplasmic reticulum stress><enroll><epigenetic gene silencing><epigenetic silencing><evaluate efficacy><examine efficacy><financial aid><financial assistance><fumarate hydrogenase><gastrointestinal tract stromal neoplasm><gastrointestinal tract stromal tumor><genetic condition><genetic disorder><genomic effort><genomic strategy><germ-line defect><germline variant><heavy metal Pb><heavy metal lead><heterogeneity in tumors><homologous recombination><imaging><imaging spectroscopy><improved><industrial partnership><industry partner><industry partnership><innovate><innovation><innovative><insight><intertumoral heterogeneity><intra-tumoral heterogeneity><intratumor heterogeneity><loss of function mutation><malignancy><methazolastone><multi-modal therapy><multi-modal treatment><multiomics><multiple omics><neoplasm/cancer><neoplastic cell><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutics><novel therapy><objective response rate><oncologic surgery><ontogeny><panomics><pathway><patient advocacy group><pediatric><phase 2 trial><phase II protocol><phase II trial><preclinical findings><preclinical information><predict therapeutic response><predict therapy response><prognostic biomarker><prognostic indicator><prognostication><promoter><promotor><receptor><response><spectroscopic imaging><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><temozolomide><therapeutically effective><therapy prediction><tool><transcriptomics><translation research><translational investigation><translational investigator><translational researcher><translational scientist><treatment prediction><treatment response prediction><treatment strategy><tumor><tumor cell metastasis><tumor heterogeneity><unclassified variant><validations><variant of uncertain clinical significance><variant of uncertain significance><variant of undetermined significance><variant of unknown significance><well-being><wellbeing><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Austin Robert Graves

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$616,585
FY 2026

Project Title

Tools to enable brain wide chronic electrophysiology in freely moving rodents

Grant Number:

1R01NS142455-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2026

End Date:

4/30/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary: The pending introduction of the 1536 channel probe Neuropixels 2.0 Quad Base in Q2 2024 followed by the much smaller 1536 channel Neuropixels NXT Probe (developed entirely with support from NIH U01 NS115587) will open a path to brain wide electrophysiology recording. However, the ch...

Research Terms

<Acceleration><Address><Algorithms><Ammon Horn><Anatomic Sites><Anatomic structures><Anatomy><Animals><Behavior><Behavioral><Benchmarking><Best Practice Analysis><Brain><Brain Nervous System><Brain region><Cell Communication and Signaling><Cell Signaling><Chronic><Common Rat Strains><Communities><Complex><Computer software><Cornu Ammonis><Data><Data Analyses><Data Analysis><Data Compression><Data Set><Decision Making><Development><Digestion><Electrodes><Electrophysiology><Electrophysiology (science)><Elements><Encephalon><Engineering><Exercise><Experimental Designs><Failure><Future><Generations><Goals><Grant><Grips><Hippocampus><Hour><Implant><Individual><Intracellular Communication and Signaling><Learning><Location><Manuals><Memory><Mice><Mice Mammals><Modeling><Murine><Mus><NIH><National Institutes of Health><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurophysiology / Electrophysiology><Neurosciences><Operative Procedures><Operative Surgical Procedures><Outcome><Performance><Physiology><Position><Positioning Attribute><Prefrontal Cortex><Process><Property><Rat><Rats Mammals><Rattus><Risk><Robotics><Rodent><Rodent Model><Rodentia><Rodents Mammals><Scientist><Si element><Signal Transduction><Signal Transduction Systems><Signaling><Silicon><Skull><Sleep><Software><Sorting><Speed><Standardization><Structure><Surgical><Surgical Interventions><Surgical Procedure><System><Techniques><Technology><Testing><Thalamic structure><Thalamus><Time><Training><United States National Institutes of Health><Validation><Work><automated analysis><base><bases><benchmark><biological signal transduction><compression algorithm><cost><cranium><curating data><data acquisition><data acquisitions><data curation><data interpretation><design><designing><developmental><disease model><disorder model><electrophysiological><experiment><experimental research><experimental study><experiments><flexibility><flexible><grasp><hippocampal><implantation><improved><large data sets><large datasets><large scale data><large scale data sets><large scale datasets><light weight><lightweight><long-term memory><member><multidisciplinary><neural><neural correlate><neuronal><new approaches><new technology><next generation><novel><novel approaches><novel strategies><novel strategy><novel technologies><robot assistance><robot assisted><robotic assistance><spatial navigation><surgery><terabyte><thalamic><tool><validations><way finding><wayfinding>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

TIMOTHY D HARRIS

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$616,585
FY 2026

Project Title

Tools to enable brain wide chronic electrophysiology in freely moving rodents

Grant Number:

1R01NS142455-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2026

End Date:

4/30/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary: The pending introduction of the 1536 channel probe Neuropixels 2.0 Quad Base in Q2 2024 followed by the much smaller 1536 channel Neuropixels NXT Probe (developed entirely with support from NIH U01 NS115587) will open a path to brain wide electrophysiology recording. However, the ch...

Research Terms

<Acceleration><Address><Algorithms><Ammon Horn><Anatomic Sites><Anatomic structures><Anatomy><Animals><Behavior><Behavioral><Benchmarking><Best Practice Analysis><Brain><Brain Nervous System><Brain region><Cell Communication and Signaling><Cell Signaling><Chronic><Common Rat Strains><Communities><Complex><Computer software><Cornu Ammonis><Data><Data Analyses><Data Analysis><Data Compression><Data Set><Decision Making><Development><Digestion><Electrodes><Electrophysiology><Electrophysiology (science)><Elements><Encephalon><Engineering><Exercise><Experimental Designs><Failure><Future><Generations><Goals><Grant><Grips><Hippocampus><Hour><Implant><Individual><Intracellular Communication and Signaling><Learning><Location><Manuals><Memory><Mice><Mice Mammals><Modeling><Murine><Mus><NIH><National Institutes of Health><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurophysiology / Electrophysiology><Neurosciences><Operative Procedures><Operative Surgical Procedures><Outcome><Performance><Physiology><Position><Positioning Attribute><Prefrontal Cortex><Process><Property><Rat><Rats Mammals><Rattus><Risk><Robotics><Rodent><Rodent Model><Rodentia><Rodents Mammals><Scientist><Si element><Signal Transduction><Signal Transduction Systems><Signaling><Silicon><Skull><Sleep><Software><Sorting><Speed><Standardization><Structure><Surgical><Surgical Interventions><Surgical Procedure><System><Techniques><Technology><Testing><Thalamic structure><Thalamus><Time><Training><United States National Institutes of Health><Validation><Work><automated analysis><base><bases><benchmark><biological signal transduction><compression algorithm><cost><cranium><curating data><data acquisition><data acquisitions><data curation><data interpretation><design><designing><developmental><disease model><disorder model><electrophysiological><experiment><experimental research><experimental study><experiments><flexibility><flexible><grasp><hippocampal><implantation><improved><large data sets><large datasets><large scale data><large scale data sets><large scale datasets><light weight><lightweight><long-term memory><member><multidisciplinary><neural><neural correlate><neuronal><new approaches><new technology><next generation><novel><novel approaches><novel strategies><novel strategy><novel technologies><robot assistance><robot assisted><robotic assistance><spatial navigation><surgery><terabyte><thalamic><tool><validations><way finding><wayfinding>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kyle Bittinger

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$574,390
FY 2026

Project Title

Defining Dysbiosis and Mechanisms of Periodontitis Progression and Stability

Grant Number:

5R01DE033033-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/17/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT The overall goal of the present application is to define dysbiosis and identify microbial changes that are predictive of an ecological disruption that ultimately leads to periodontal destruction and to provide mechanistic insights into why this occurs. The major strength of ...

Research Terms

<21+ years old><Adult><Adult Human><Affect><After Care><After-Treatment><Aftercare><Airway infections><Biological><Biological Markers><Body Tissues><Calibration><Cardiovascular Diseases><Chronic Periodontitis><Clinical><Clinical Data><Computational Biology><Consumption><Coupled><Data><Diagnosis><Disease Progression><Environment><Event><Evolution><Expenditure><Funding><Future><Generations><Genomics><Gingiva><Gingival><Gingival Crevicular Fluid><Gingival Exudate><Goals><Gum Disease><Health Transition><Human><Immune response><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunology><Individual><Infection><Inflammation><Inflammatory><Intervention><Knowledge><Lead><Measures><Mediating><Mediator><Metabolic><Microbial Biofilms><Microbiology><Modeling><Modern Man><Monitor><NIDCR><NIDR><NIH><National Institute of Dental Research><National Institute of Dental and Craniofacial Research><National Institutes of Health><Natural History><Paradentium><Parodontosis><Participant><Pathogenesis><Patients><Pb element><Periodontal Diseases><Periodontitis><Periodontium><Persons><Position><Positioning Attribute><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Prospective Studies><Resource Allocation><Respiratory Infections><Respiratory Tract Infections><Risk><Risk Factors><Sampling><Shotgun Sequencing><Site><Testing><Time><Tissues><Tooth><Tooth Loss><Tooth Supporting Structures><Tooth structure><Translational Research><Translational Science><United States National Institutes of Health><Validation><adulthood><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><aging population><analyze microbiome><bacterial community><bio-informatics tool><bio-markers><biobank><biofilm><bioinformatics tool><biologic><biologic marker><biomarker><biorepository><bone loss><cardiovascular disorder><clinical practice><clinical relevance><clinically relevant><co-morbid><co-morbidity><community microbes><comorbidity><computer based prediction><computer biology><cost><cytokine><dysbacteriosis><dysbiosis><dysbiotic><experience><heavy metal Pb><heavy metal lead><host microbe association><host microbe relationship><host response><host-microbe interactions><host-microbial interactions><host-microorganism interactions><immune system response><immunoresponse><improved><insight><metabolism measurement><metabolomics><metabonomics><microbe community><microbial><microbial community><microbial consortia><microbial flora><microbial host><microbial imbalance><microbial signature><microbiome><microbiome analysis><microbiome community composition><microbiome composition><microbiome species composition><microbiome structure><microbiota><microflora><microorganism><microorganism community><multidisciplinary><multiomics><multiple omics><multispecies consortia><panomics><periodontal disorder><periodontium disease><periodontium disorder><polymicrobial community><population aging><post treatment><predictive modeling><prevent><preventing><prospective><prospective research study><prospective survey><response to therapy><response to treatment><subgingival microbiome><teeth><therapeutic response><therapy response><tool><translation research><translational investigation><treatment response><treatment responsiveness><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Flavia Rocha Teles

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$574,390
FY 2026

Project Title

Defining Dysbiosis and Mechanisms of Periodontitis Progression and Stability

Grant Number:

5R01DE033033-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/17/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT The overall goal of the present application is to define dysbiosis and identify microbial changes that are predictive of an ecological disruption that ultimately leads to periodontal destruction and to provide mechanistic insights into why this occurs. The major strength of ...

Research Terms

<21+ years old><Adult><Adult Human><Affect><After Care><After-Treatment><Aftercare><Airway infections><Biological><Biological Markers><Body Tissues><Calibration><Cardiovascular Diseases><Chronic Periodontitis><Clinical><Clinical Data><Computational Biology><Consumption><Coupled><Data><Diagnosis><Disease Progression><Environment><Event><Evolution><Expenditure><Funding><Future><Generations><Genomics><Gingiva><Gingival><Gingival Crevicular Fluid><Gingival Exudate><Goals><Gum Disease><Health Transition><Human><Immune response><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunology><Individual><Infection><Inflammation><Inflammatory><Intervention><Knowledge><Lead><Measures><Mediating><Mediator><Metabolic><Microbial Biofilms><Microbiology><Modeling><Modern Man><Monitor><NIDCR><NIDR><NIH><National Institute of Dental Research><National Institute of Dental and Craniofacial Research><National Institutes of Health><Natural History><Paradentium><Parodontosis><Participant><Pathogenesis><Patients><Pb element><Periodontal Diseases><Periodontitis><Periodontium><Persons><Position><Positioning Attribute><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Prospective Studies><Resource Allocation><Respiratory Infections><Respiratory Tract Infections><Risk><Risk Factors><Sampling><Shotgun Sequencing><Site><Testing><Time><Tissues><Tooth><Tooth Loss><Tooth Supporting Structures><Tooth structure><Translational Research><Translational Science><United States National Institutes of Health><Validation><adulthood><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><aging population><analyze microbiome><bacterial community><bio-informatics tool><bio-markers><biobank><biofilm><bioinformatics tool><biologic><biologic marker><biomarker><biorepository><bone loss><cardiovascular disorder><clinical practice><clinical relevance><clinically relevant><co-morbid><co-morbidity><community microbes><comorbidity><computer based prediction><computer biology><cost><cytokine><dysbacteriosis><dysbiosis><dysbiotic><experience><heavy metal Pb><heavy metal lead><host microbe association><host microbe relationship><host response><host-microbe interactions><host-microbial interactions><host-microorganism interactions><immune system response><immunoresponse><improved><insight><metabolism measurement><metabolomics><metabonomics><microbe community><microbial><microbial community><microbial consortia><microbial flora><microbial host><microbial imbalance><microbial signature><microbiome><microbiome analysis><microbiome community composition><microbiome composition><microbiome species composition><microbiome structure><microbiota><microflora><microorganism><microorganism community><multidisciplinary><multiomics><multiple omics><multispecies consortia><panomics><periodontal disorder><periodontium disease><periodontium disorder><polymicrobial community><population aging><post treatment><predictive modeling><prevent><preventing><prospective><prospective research study><prospective survey><response to therapy><response to treatment><subgingival microbiome><teeth><therapeutic response><therapy response><tool><translation research><translational investigation><treatment response><treatment responsiveness><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Geoffrey Camirand

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

High-opportunity lead · 74/100
Likely hiring
Solid budget
Very recent
Active award
$394,733
FY 2026

Project Title

Promoting and Visualizing Immune Regulation in Transplantation

Grant Number:

5U01AI170074-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/13/2022

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Two main issues currently plague the field of transplantation in humans: (i) poor control of chronic rejection by current immunosuppressive drugs; and (ii) low success of tolerance induction. At the center of these issues is innate immune memory stemming from both innate allorecogni...

Research Terms

<Affect><Allogeneic Transplantation><Allografting><Applications Grants><Autoregulation><CD11c><Calcineurin><Calcineurin antagonist><Calcineurin inhibitor><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chronic><Data><Drugs><Environment><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><FOXP3><FOXP3 gene><Forkhead Box P3><Genetic><Graft Rejection><Graft Survival><Grant><Grant Proposals><Homeostasis><Homologous Transplantation><Human><ITGAX><ITGAX gene><Immune><Immune memory><Immunes><Immunity><Immunobiology><Immunologic Memory><Immunological Memory><Immunomodulation><Immunophysiology><Immunosuppressants><Immunosuppression><Immunosuppression Effect><Immunosuppressive Agents><Immunosuppressive Effect><Immunosuppressive drug><Immunosuppressive treatment><Infiltration><Inflammation><Intracellular Communication and Signaling><JM2><Knowledge><Medication><Mice><Mice Mammals><Modern Man><Molecular Target><Murine><Mus><Myelogenous><Myeloid><NF-AT><NF-AT proteins><NFAT proteins><NFAT-1><NFATC proteins><PP2B><Pathway interactions><Pharmaceutical Preparations><Phenotype><Physiological Homeostasis><Position><Positioning Attribute><Process><Protein Phosphatase-2B><Receptor Protein><Regimen><Regulatory T-Lymphocyte><Role><SCURFIN><Science><Signal Transduction><Signal Transduction Systems><Signaling><Subcellular Process><Technology><Teff cell><Testing><Therapeutic><Time><Training><Transplant Rejection><Transplantation><Transplantation Rejection><Treg><Visualization><allograft rejection><anamnestic reaction><biological signal transduction><cytoplasmic nuclear factor of activated T-cells><drug/agent><effector T cell><epigenetically><experiment><experimental research><experimental study><experiments><genetic approach><genetic strategy><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive agent><immune suppressive function><immune suppressor><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunosuppressive substance><immunosuppressor><improved><intra-vital imaging><intra-vital microscopy><intravital imaging><intravital microscopy><mTOR Inhibitor><multi-photon><nano particle><nano-biological><nano-sized particle><nanobiologic><nanobiological particle><nanoparticle><nanosized particle><nanotherapeutic><novel><nuclear factors of activated T-cells><pathway><prevent><preventing><receptor><regulatory T-cells><secondary immune response><social role><stem><success><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic target><transcription factor NF-AT><transplant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ADAM L. BOXER

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$16,947,844
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

2U19AG063911-06

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bradley F Boeve

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$16,947,844
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

2U19AG063911-06

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HOWARD J ROSEN

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$16,947,844
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

2U19AG063911-06

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Paul K Crane

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$11,629,456
FY 2025

Project Title

Adult Changes in Thought (ACT) Research Program

Grant Number:

5U19AG066567-05

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2021

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The Adult Changes in Thought (ACT) U19 Program will expand, modernize, and improve ACT's prospective cohort study to achieve advances in scientific understanding of older adults in general and dementia and Alzheimer's disease in particular. ACT is set in a healthcare delivery system. The study team ...

Research Terms

<21+ years old><AD dementia><AD related dementia><ADRD><Accelerometer><Acetylcholine Agents><Active Follow-up><Adopted><Adult><Adult Human><Affect><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimers Dementia><Amentia><American><Amyloid (Aβ) plaques><Amyloid Plaques><Anti-Cholinergics><Anti-Hypertensive Agents><Anti-Hypertensive Drugs><Anti-Hypertensives><Anticholinergic Agents><Anticholinergics><Assay><Autopsy><Behavioral Sciences><Bioassay><Biological Assay><Biological Markers><Biology><Bionomics><Brain><Brain Nervous System><Care Givers><Caregivers><Caring><Causality><Cause of Death><Cell Body><Cells><Cholinergic Agents><Cholinergic Drugs><Clinical><Clinical Data><Clinical Research><Clinical Study><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive Manifestations><Cognitive Symptoms><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Communities><Complex><Conceptions><Concurrent Studies><Consent><Country><D-Glucose><Data><Data Set><Dementia><Development><Devices><Dextrose><Diabetes Mellitus><Diagnosis><Discipline><Disturbance in cognition><Drugs><Ecology><Economics><Encephalon><Enrollment><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><Etiology><Exercise><Family><Fear><Foundations><Fright><Funding><Future><Glucose><Goals><Grant><History><Hour><Human><Hypotensive Agent><Hypotensive Drugs><Image><Impaired cognition><Incidence><Individual><Influentials><Intervention><Investigation><Investigators><Investments><LB dementia><Learning><Lewy Body Dementia><Lewy Body Type Senile Dementia><Lewy dementia><Life><Life Cycle><Life Cycle Stages><MRI Scans><Magnetic Resonance Imaging Scan><Measures><Medication><Mentorship><Methods><Modern Man><Modernization><Movement><National Institute of Aging><National Institute on Aging><Nerve Cells><Nerve Degeneration><Nerve Unit><Neural Cell><Neuritic Plaques><Neurobehavioral Manifestations><Neurobehavioral Signs and Symptoms><Neurocyte><Neuron Degeneration><Neurons><Older Population><Outcome><Participant><Persons><Pharmaceutical Epidemiology><Pharmaceutical Preparations><Pharmacoepidemiology><Phenotype><Physical Function><Physical Performance><Physical activity><Policies><Position><Positioning Attribute><Prevalence><Prevention><Primary Senile Degenerative Dementia><Process><Progenitor Cells><Prospective Studies><Prospective, cohort study><Race><Races><Recording of previous events><Records><Reproducibility><Research><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Risk><Risk Factors><Sample Size><Science><Scientist><Sedentary behavior><Sedentary life-style><Senile Plaques><Series><Specimen><Subgroup><System><Toxic effect><Toxicities><Visit><Work><accelerometry><active followup><activity monitor><activity tracker><adulthood><age associated disease><age associated disorder><age associated impairment><age dependent disease><age dependent disorder><age dependent impairment><age related human disease><age-related disease><age-related disorder><age-related impairment><aged brain><aging associated><aging brain><aging related><alzheimer risk><amyloid beta plaque><amyloid-b plaque><anti-hypertension><aβ plaques><bio-markers><biologic marker><biomarker><body movement><causation><clinical care><clinical diagnosis><cognitive dysfunction><cognitive function><cognitive loss><cognitive performance><cohort><cored plaque><data resource><data sharing><density><design><designing><developmental><diabetes><diffuse plaque><disease causation><disease subgroups><disease subtype><disorder subtype><drug epidemiology><drug/agent><economic><enroll><epidemiologic investigation><epidemiology study><ethnic diversity><ethnically diverse><follow up><follow-up><followed up><followup><health and care delivery><health care delivery><health delivery systems><health services delivery><high risk><histories><imaging><improved><indexing><interoperability><late in life><late life><life course><necropsy><neural><neural degeneration><neural imaging><neuro-imaging><neurobehavioral symptom><neurodegeneration><neurodegenerative><neuroimaging><neurological degeneration><neurological imaging><neuronal><neuronal degeneration><neuropathologic><neuropathological><neuropathology><old age><older adult><older adulthood><older groups><older individuals><older person><participant enrollment><patient enrollment><pharmacoepidemiologic><pharmacoepidemiological><physical conditioning><physical health><postmortem><preservation><prevent><preventing><primary degenerative dementia><programs><prospective><racial><racial background><racial origin><recruit><resilience><resilience factor><resiliency factor><resilient><sedentary lifestyle><senile dementia of the Alzheimer type><sleep pattern><sleep routine><sleep schedule><sleep/wake patterns><socio-economic diversity><socioeconomic diversity><stem cells><tissue resource><tool><web site><website>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrea Z. LaCroix

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$11,629,456
FY 2025

Project Title

Adult Changes in Thought (ACT) Research Program

Grant Number:

5U19AG066567-05

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2021

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The Adult Changes in Thought (ACT) U19 Program will expand, modernize, and improve ACT's prospective cohort study to achieve advances in scientific understanding of older adults in general and dementia and Alzheimer's disease in particular. ACT is set in a healthcare delivery system. The study team ...

Research Terms

<21+ years old><AD dementia><AD related dementia><ADRD><Accelerometer><Acetylcholine Agents><Active Follow-up><Adopted><Adult><Adult Human><Affect><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimers Dementia><Amentia><American><Amyloid (Aβ) plaques><Amyloid Plaques><Anti-Cholinergics><Anti-Hypertensive Agents><Anti-Hypertensive Drugs><Anti-Hypertensives><Anticholinergic Agents><Anticholinergics><Assay><Autopsy><Behavioral Sciences><Bioassay><Biological Assay><Biological Markers><Biology><Bionomics><Brain><Brain Nervous System><Care Givers><Caregivers><Caring><Causality><Cause of Death><Cell Body><Cells><Cholinergic Agents><Cholinergic Drugs><Clinical><Clinical Data><Clinical Research><Clinical Study><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive Manifestations><Cognitive Symptoms><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Communities><Complex><Conceptions><Concurrent Studies><Consent><Country><D-Glucose><Data><Data Set><Dementia><Development><Devices><Dextrose><Diabetes Mellitus><Diagnosis><Discipline><Disturbance in cognition><Drugs><Ecology><Economics><Encephalon><Enrollment><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><Etiology><Exercise><Family><Fear><Foundations><Fright><Funding><Future><Glucose><Goals><Grant><History><Hour><Human><Hypotensive Agent><Hypotensive Drugs><Image><Impaired cognition><Incidence><Individual><Influentials><Intervention><Investigation><Investigators><Investments><LB dementia><Learning><Lewy Body Dementia><Lewy Body Type Senile Dementia><Lewy dementia><Life><Life Cycle><Life Cycle Stages><MRI Scans><Magnetic Resonance Imaging Scan><Measures><Medication><Mentorship><Methods><Modern Man><Modernization><Movement><National Institute of Aging><National Institute on Aging><Nerve Cells><Nerve Degeneration><Nerve Unit><Neural Cell><Neuritic Plaques><Neurobehavioral Manifestations><Neurobehavioral Signs and Symptoms><Neurocyte><Neuron Degeneration><Neurons><Older Population><Outcome><Participant><Persons><Pharmaceutical Epidemiology><Pharmaceutical Preparations><Pharmacoepidemiology><Phenotype><Physical Function><Physical Performance><Physical activity><Policies><Position><Positioning Attribute><Prevalence><Prevention><Primary Senile Degenerative Dementia><Process><Progenitor Cells><Prospective Studies><Prospective, cohort study><Race><Races><Recording of previous events><Records><Reproducibility><Research><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Risk><Risk Factors><Sample Size><Science><Scientist><Sedentary behavior><Sedentary life-style><Senile Plaques><Series><Specimen><Subgroup><System><Toxic effect><Toxicities><Visit><Work><accelerometry><active followup><activity monitor><activity tracker><adulthood><age associated disease><age associated disorder><age associated impairment><age dependent disease><age dependent disorder><age dependent impairment><age related human disease><age-related disease><age-related disorder><age-related impairment><aged brain><aging associated><aging brain><aging related><alzheimer risk><amyloid beta plaque><amyloid-b plaque><anti-hypertension><aβ plaques><bio-markers><biologic marker><biomarker><body movement><causation><clinical care><clinical diagnosis><cognitive dysfunction><cognitive function><cognitive loss><cognitive performance><cohort><cored plaque><data resource><data sharing><density><design><designing><developmental><diabetes><diffuse plaque><disease causation><disease subgroups><disease subtype><disorder subtype><drug epidemiology><drug/agent><economic><enroll><epidemiologic investigation><epidemiology study><ethnic diversity><ethnically diverse><follow up><follow-up><followed up><followup><health and care delivery><health care delivery><health delivery systems><health services delivery><high risk><histories><imaging><improved><indexing><interoperability><late in life><late life><life course><necropsy><neural><neural degeneration><neural imaging><neuro-imaging><neurobehavioral symptom><neurodegeneration><neurodegenerative><neuroimaging><neurological degeneration><neurological imaging><neuronal><neuronal degeneration><neuropathologic><neuropathological><neuropathology><old age><older adult><older adulthood><older groups><older individuals><older person><participant enrollment><patient enrollment><pharmacoepidemiologic><pharmacoepidemiological><physical conditioning><physical health><postmortem><preservation><prevent><preventing><primary degenerative dementia><programs><prospective><racial><racial background><racial origin><recruit><resilience><resilience factor><resiliency factor><resilient><sedentary lifestyle><senile dementia of the Alzheimer type><sleep pattern><sleep routine><sleep schedule><sleep/wake patterns><socio-economic diversity><socioeconomic diversity><stem cells><tissue resource><tool><web site><website>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Linda Kathleen McEvoy

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$11,629,456
FY 2025

Project Title

Adult Changes in Thought (ACT) Research Program

Grant Number:

5U19AG066567-05

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2021

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The Adult Changes in Thought (ACT) U19 Program will expand, modernize, and improve ACT's prospective cohort study to achieve advances in scientific understanding of older adults in general and dementia and Alzheimer's disease in particular. ACT is set in a healthcare delivery system. The study team ...

Research Terms

<21+ years old><AD dementia><AD related dementia><ADRD><Accelerometer><Acetylcholine Agents><Active Follow-up><Adopted><Adult><Adult Human><Affect><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimers Dementia><Amentia><American><Amyloid (Aβ) plaques><Amyloid Plaques><Anti-Cholinergics><Anti-Hypertensive Agents><Anti-Hypertensive Drugs><Anti-Hypertensives><Anticholinergic Agents><Anticholinergics><Assay><Autopsy><Behavioral Sciences><Bioassay><Biological Assay><Biological Markers><Biology><Bionomics><Brain><Brain Nervous System><Care Givers><Caregivers><Caring><Causality><Cause of Death><Cell Body><Cells><Cholinergic Agents><Cholinergic Drugs><Clinical><Clinical Data><Clinical Research><Clinical Study><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive Manifestations><Cognitive Symptoms><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Communities><Complex><Conceptions><Concurrent Studies><Consent><Country><D-Glucose><Data><Data Set><Dementia><Development><Devices><Dextrose><Diabetes Mellitus><Diagnosis><Discipline><Disturbance in cognition><Drugs><Ecology><Economics><Encephalon><Enrollment><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><Etiology><Exercise><Family><Fear><Foundations><Fright><Funding><Future><Glucose><Goals><Grant><History><Hour><Human><Hypotensive Agent><Hypotensive Drugs><Image><Impaired cognition><Incidence><Individual><Influentials><Intervention><Investigation><Investigators><Investments><LB dementia><Learning><Lewy Body Dementia><Lewy Body Type Senile Dementia><Lewy dementia><Life><Life Cycle><Life Cycle Stages><MRI Scans><Magnetic Resonance Imaging Scan><Measures><Medication><Mentorship><Methods><Modern Man><Modernization><Movement><National Institute of Aging><National Institute on Aging><Nerve Cells><Nerve Degeneration><Nerve Unit><Neural Cell><Neuritic Plaques><Neurobehavioral Manifestations><Neurobehavioral Signs and Symptoms><Neurocyte><Neuron Degeneration><Neurons><Older Population><Outcome><Participant><Persons><Pharmaceutical Epidemiology><Pharmaceutical Preparations><Pharmacoepidemiology><Phenotype><Physical Function><Physical Performance><Physical activity><Policies><Position><Positioning Attribute><Prevalence><Prevention><Primary Senile Degenerative Dementia><Process><Progenitor Cells><Prospective Studies><Prospective, cohort study><Race><Races><Recording of previous events><Records><Reproducibility><Research><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Risk><Risk Factors><Sample Size><Science><Scientist><Sedentary behavior><Sedentary life-style><Senile Plaques><Series><Specimen><Subgroup><System><Toxic effect><Toxicities><Visit><Work><accelerometry><active followup><activity monitor><activity tracker><adulthood><age associated disease><age associated disorder><age associated impairment><age dependent disease><age dependent disorder><age dependent impairment><age related human disease><age-related disease><age-related disorder><age-related impairment><aged brain><aging associated><aging brain><aging related><alzheimer risk><amyloid beta plaque><amyloid-b plaque><anti-hypertension><aβ plaques><bio-markers><biologic marker><biomarker><body movement><causation><clinical care><clinical diagnosis><cognitive dysfunction><cognitive function><cognitive loss><cognitive performance><cohort><cored plaque><data resource><data sharing><density><design><designing><developmental><diabetes><diffuse plaque><disease causation><disease subgroups><disease subtype><disorder subtype><drug epidemiology><drug/agent><economic><enroll><epidemiologic investigation><epidemiology study><ethnic diversity><ethnically diverse><follow up><follow-up><followed up><followup><health and care delivery><health care delivery><health delivery systems><health services delivery><high risk><histories><imaging><improved><indexing><interoperability><late in life><late life><life course><necropsy><neural><neural degeneration><neural imaging><neuro-imaging><neurobehavioral symptom><neurodegeneration><neurodegenerative><neuroimaging><neurological degeneration><neurological imaging><neuronal><neuronal degeneration><neuropathologic><neuropathological><neuropathology><old age><older adult><older adulthood><older groups><older individuals><older person><participant enrollment><patient enrollment><pharmacoepidemiologic><pharmacoepidemiological><physical conditioning><physical health><postmortem><preservation><prevent><preventing><primary degenerative dementia><programs><prospective><racial><racial background><racial origin><recruit><resilience><resilience factor><resiliency factor><resilient><sedentary lifestyle><senile dementia of the Alzheimer type><sleep pattern><sleep routine><sleep schedule><sleep/wake patterns><socio-economic diversity><socioeconomic diversity><stem cells><tissue resource><tool><web site><website>
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Arie Kapteyn

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$8,819,742
FY 2025

Project Title

A Next Generation Data Infrastructure to Understand Disparities across the Life Course

Grant Number:

3U01AG077280-03S1A1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2023

End Date:

7/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Alzheimer’s disease and related dementias (ADRD) are an escalating public health crisis that affects >30% of seniors and costs $300-640B annually in the US. ADRD disproportionately harms certain phenotypic subgroups like individuals with diabetes, that experience higher rates and earlier onset. Beha...

Research Terms

<AD model><AD related dementia><ADRD><AI model training><AI system><AI training><Activities of Daily Living><Activities of everyday life><Address><Affect><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Amentia><American><Artificial Intelligence><Artificial intelligence model training><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Benchmarking><Best Practice Analysis><Biological><Cardiac Chronotropism><Chronic><Classification><Clinical><Clinical assessments><Cognition><Cognitive><Complex><Computer Reasoning><Conditioning Therapy><Data><Data Collection><Data Set><Dementia><Detection><Development><Diabetes Mellitus><Diagnosis><Dimensions><Disparities><Disparity><Early Diagnosis><Ecological momentary assessment><Economic Burden><Electronics><Enrollment><Exhibits><FAIR data><FAIR guiding principles><FAIR principles><Face><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Frequencies><Future><General Population><General Public><Health><Health Care><Heart Rate><Heterogeneity><Impairment><In Situ><Individual><Infrastructure><Internet><Intervention><Label><Life><Life Cycle><Life Cycle Stages><Lived experience><Lived experiences><Machine Intelligence><Machine Learning><Measures><Methods><Modeling><Outcome><Parents><Participant><Pathway interactions><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Performance><Persons><Phenotype><Physiologic><Physiological><Population><Population Characteristics><Population Heterogeneity><Population Study><Precision Health><Prevention><Probability><Protocol><Protocols documentation><Public Health><Quasi-experiment><Quasi-experimental analysis><Quasi-experimental approach><Quasi-experimental design><Quasi-experimental methods><Quasi-experimental research><Quasi-experimental study><Quasi-experimental technique><Reproducibility><Risk><Risk Factors><Role><Sample Size><Sampling><Sleep><Standardization><Subgroup><Survey Instrument><Surveys><Symptoms><Systematics><Testing><Time><Training><Validation><WWW><alzheimer model><applied learning><artificial intelligence training><automated assessment><automated evaluation><automated intervention><behavior intervention><behavioral intervention><benchmark><biobank><biobehavior><biobehavioral><biologic><biorepository><clinical relevance><clinically relevant><cognitive ability><cognitive assessment><cognitive change><cognitive impairment no dementia><cognitive testing><cohort><cost><cost effective><daily living function><daily living functionality><data infrastructure><data streams><dementia burden><dementia risk><design><designing><developmental><diabetes><digital data><digital technology><diverse populations><early detection><early onset><electronic><electronic device><enroll><experience><faces><facial><fitbit><functional ability><functional capacity><hands-on learning><health application><health data><heterogeneous population><improved><instrument><interactive engagement><interactive learning><large scale data><large scale data sets><large scale datasets><life course><machine based learning><machine learning based method><machine learning based model><machine learning method><machine learning methodologies><machine learning model><malleable risk><mild cognitive disorder><mild cognitive impairment><modifiable risk><natural aging><next generation><normal aging><normative aging><older adult><older adulthood><parent><pathway><population diversity><population-based study><population-level study><prevent><preventing><psychosocial><recruit><response><risk factor for dementia><risk for dementia><social role><studies of populations><study of the population><validations><wearable><wearable device><wearable electronics><wearable system><wearable technology><wearable tool><wearables><web><world wide web>
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CAROL D. RYFF

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$6,878,376
FY 2025

Project Title

Integrative Pathways to Health and Illness

Grant Number:

5U19AG051426-09

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/25/2016

End Date:

8/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT – MIDUS OVERALL PLAN The Midlife in the U.S. (MIDUS) national longitudinal study has been ongoing since 1995. MIDUS is the only national study focused on midlife with a wide age expanse at baseline. MIDUS also has unusual depth in its psychosocial, biomarker, genomic, and neuroscience asses...

Research Terms

<21+ years old><AD dementia><AD related dementia><ADRD><Active Follow-up><Adult><Adult Human><Age><Age Distribution><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Archives><Assay><Attention><Baseline Surveys><Behavioral><Bioassay><Biological><Biological Assay><Biological Markers><Biology><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Chronic><Clinical Trials Data Monitoring Committees><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Communities><Complex><Data><Data Collection><Data Monitoring Committees><Data Set><Data and Safety Monitoring Boards><Disturbance in cognition><Documentation><Drops><Educational workshop><Ensure><Event><Funding><Gene Action Regulation><Gene Expression><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Genomics><Health><Health Inequity><Health Sciences><Impaired cognition><Individual><Inequalities in Health><Inequality><Inequities in Health><Intervention><Knowledge><Life><Link><Longitudinal Studies><Measures><Metadata><Methodology><Minority><Modeling><Monitor><Morbidity><Morbidity - disease rate><National Archive><Neurobiology><Neurosciences><Outcome><Participant><Pathway interactions><Personal Satisfaction><Persons><Physiology><Politics><Prevention><Primary Senile Degenerative Dementia><Psychosocial Assessment and Care><Psychosocial Factor><Publications><Publishing><Quality Control><Recurrence><Recurrent><Research><Research Resources><Resources><Running><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SES disparity><Safety Monitoring Boards><Sample Size><Sampling><Scientific Publication><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Stress><Survey Instrument><Surveys><Testing><Time><Translating><Universities><Work><Workshop><active followup><adulthood><affective neuroscience><aged><aged brain><ages><aging brain><bio-markers><biologic><biologic marker><biomarker><biopsychosocial><build resilience><build resiliency><care giving><caregiving><cognitive assessment><cognitive dysfunction><cognitive function><cognitive loss><cognitive testing><computerized><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><design><designing><develop resilience><develop resiliency><diaries><disparities in race><disparity due to race><emotion regulation><emotional regulation><enhance resilience><enhance resiliency><experience><experienced discrimination><facilitate resilience><follow up><follow-up><followed up><followup><genomic data><genomic dataset><health inequalities><healthy aging><healthy human aging><improve resilience><improve resiliency><increase resilience><increase resiliency><inequality due to race><inequity due to race><journal article><later in life><later life><long-term study><longitudinal outcome studies><meta data><mid life><mid-life><middle age><middle aged><midlife><mortality><neurobiological><neurobiological mechanism><pathway><perceived discrimination><perception of discrimination><prevent><preventing><primary degenerative dementia><promote resilience><promote resiliency><protective factors><psychologic><psychological><psychosocial><psychosocial assessment><psychosocial care><psychosocial resources><psychosocial studies><psychosocial support><psychosocial variables><public health relevance><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><recruit><research on resilience><research on resiliency><resilience><resilience development><resilience research><resiliency research><resilient><self-reported discrimination><senile dementia of the Alzheimer type><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social><socio-demographic factors><socio-demographics><socio-economic><socio-economic disparity><socio-economic inequality><socio-economic inequity><socio-economically><sociodemographic factors><sociodemographics><socioeconomic disparity><socioeconomic inequality><socioeconomic inequity><socioeconomically><socioeconomics><statistical analysis core><statistical core><statistics core><statistics research core><tool><virtual><well-being><wellbeing>
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Peter Scott Heeger

CEDARS-SINAI MEDICAL CENTER, LOS ANGELES, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$5,352,674
FY 2025

Project Title

Assessment of Biomarker Guided CNI Substitution in Kidney Transplantation

Grant Number:

5U01AI170424-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2022

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Current standard of care for kidney transplant (KTx) recipients has only modestly improved long-term aggregate graft and/or patient survival, identifying a crucial unmet medical need. As the at-risk KTx population is heterogeneous, the currently employed and relatively homogeneous therapeutic approa...

Research Terms

<1, 2-Dehydrocortisone><3-D><3-Dimensional><3D><Active Follow-up><Acute><Address><Affect><Allografting><Biological Markers><Biopsy><Calcineurin antagonist><Calcineurin inhibitor><Canada><Cessation of life><Characteristics><Clinical><Clinical Trials><Death><Dehydrocortisone><Delta(1)-Cortisone><Deltacortisone><Deltadehydrocortisone><Enrollment><Ensure><Event><FDA approved><Failure><Future><Glomerular Filtration Rate><Goals><HLA testing><HLA typing><HLA-BR><HLA-BR Antigens><HLA-D-Related Antigens><HLA-DR><HLA-DR Antigens><HLA-MT><HLA-MT Antigens><Health><Human><Imaging Procedures><Imaging Technics><Imaging Techniques><Immune><Immune Markers><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunological><Immunologically><Immunologics><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Infrastructure><Infusion><Infusion procedures><Injury><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Life><Mediating><Medical><Metacortandracin><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><Morbidity - disease rate><Multi-center studies><Multi-center trial><Multicenter Studies><Multicenter Trials><Mycophenolic Acid><NIH><National Institutes of Health><Neurocognitive><Observation research><Observation study><Observational Study><Observational research><Outcome><Outcome Measure><Pathway interactions><Patient Outcomes Assessments><Patient Participation><Patient Reported Measures><Patient Reported Outcomes><Patients><Phenotype><Population><Prednisone><Prednisonum><Productivity><Prognostic Marker><Prospective Studies><Protocol><Protocols documentation><Randomized><Randomized, Controlled Trials><Renal Grafting><Renal Transplantation><Renal Transplants><Research Design><Retrospective Studies><Risk><Safety><Self Administered><Self Administration><Stratification><Study Type><T cell receptor repertoire sequencing><T cell receptor sequencing><T-Cells><T-Lymphocyte><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><Tacrolimus><Testing><Therapeutic><Time><Toxic effect><Toxicities><Transplant Recipients><Transplantation><United States National Institutes of Health><Work><active followup><alloimmunity><antibody rejection><antibody-mediated rejection><arm><bio-markers><biologic marker><biomarker><clinical care><cohort><delta-Cortisone><design><designing><donor antibodies><donor-specific antibody><enroll><evidence base><fibrogenesis><follow up><follow-up><followed up><followup><graft function><human leukocyte antigen testing><human leukocyte antigen typing><immune suppression><immune suppressive activity><immune suppressive function><immune-based biomarkers><immunological biomarkers><immunological markers><immunosuppressed><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><improved outcome><infusions><injuries><insight><instrument><isoimmunity><kidney allograft><kidney tx><measurable outcome><molecular profile><molecular signature><novel><outcome measurement><outcome prediction><pathway><peripheral blood><post-transplant><post-transplantation><posttransplant><posttransplantation><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><primary end point><primary endpoint><prognostic biomarker><prognostic indicator><prospective><prospective test><racial diversity><racially diverse><randomisation><randomization><randomized control trial><randomly assigned><renal allograft><risk stratification><secondary end point><secondary endpoint><specific biomarkers><standard of care><stratify risk><study design><subcutaneous><subdermal><success><three dimensional><thymus derived lymphocyte><transplant><transplant patient><vascular constriction><vasoconstriction>
View Full Project Details on NIH Reporter
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PETER W NICKERSON

CEDARS-SINAI MEDICAL CENTER, LOS ANGELES, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$5,352,674
FY 2025

Project Title

Assessment of Biomarker Guided CNI Substitution in Kidney Transplantation

Grant Number:

5U01AI170424-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2022

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Current standard of care for kidney transplant (KTx) recipients has only modestly improved long-term aggregate graft and/or patient survival, identifying a crucial unmet medical need. As the at-risk KTx population is heterogeneous, the currently employed and relatively homogeneous therapeutic approa...

Research Terms

<1, 2-Dehydrocortisone><3-D><3-Dimensional><3D><Active Follow-up><Acute><Address><Affect><Allografting><Biological Markers><Biopsy><Calcineurin antagonist><Calcineurin inhibitor><Canada><Cessation of life><Characteristics><Clinical><Clinical Trials><Death><Dehydrocortisone><Delta(1)-Cortisone><Deltacortisone><Deltadehydrocortisone><Enrollment><Ensure><Event><FDA approved><Failure><Future><Glomerular Filtration Rate><Goals><HLA testing><HLA typing><HLA-BR><HLA-BR Antigens><HLA-D-Related Antigens><HLA-DR><HLA-DR Antigens><HLA-MT><HLA-MT Antigens><Health><Human><Imaging Procedures><Imaging Technics><Imaging Techniques><Immune><Immune Markers><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunological><Immunologically><Immunologics><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Infrastructure><Infusion><Infusion procedures><Injury><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Life><Mediating><Medical><Metacortandracin><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><Morbidity - disease rate><Multi-center studies><Multi-center trial><Multicenter Studies><Multicenter Trials><Mycophenolic Acid><NIH><National Institutes of Health><Neurocognitive><Observation research><Observation study><Observational Study><Observational research><Outcome><Outcome Measure><Pathway interactions><Patient Outcomes Assessments><Patient Participation><Patient Reported Measures><Patient Reported Outcomes><Patients><Phenotype><Population><Prednisone><Prednisonum><Productivity><Prognostic Marker><Prospective Studies><Protocol><Protocols documentation><Randomized><Randomized, Controlled Trials><Renal Grafting><Renal Transplantation><Renal Transplants><Research Design><Retrospective Studies><Risk><Safety><Self Administered><Self Administration><Stratification><Study Type><T cell receptor repertoire sequencing><T cell receptor sequencing><T-Cells><T-Lymphocyte><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><Tacrolimus><Testing><Therapeutic><Time><Toxic effect><Toxicities><Transplant Recipients><Transplantation><United States National Institutes of Health><Work><active followup><alloimmunity><antibody rejection><antibody-mediated rejection><arm><bio-markers><biologic marker><biomarker><clinical care><cohort><delta-Cortisone><design><designing><donor antibodies><donor-specific antibody><enroll><evidence base><fibrogenesis><follow up><follow-up><followed up><followup><graft function><human leukocyte antigen testing><human leukocyte antigen typing><immune suppression><immune suppressive activity><immune suppressive function><immune-based biomarkers><immunological biomarkers><immunological markers><immunosuppressed><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><improved outcome><infusions><injuries><insight><instrument><isoimmunity><kidney allograft><kidney tx><measurable outcome><molecular profile><molecular signature><novel><outcome measurement><outcome prediction><pathway><peripheral blood><post-transplant><post-transplantation><posttransplant><posttransplantation><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><primary end point><primary endpoint><prognostic biomarker><prognostic indicator><prospective><prospective test><racial diversity><racially diverse><randomisation><randomization><randomized control trial><randomly assigned><renal allograft><risk stratification><secondary end point><secondary endpoint><specific biomarkers><standard of care><stratify risk><study design><subcutaneous><subdermal><success><three dimensional><thymus derived lymphocyte><transplant><transplant patient><vascular constriction><vasoconstriction>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

AUBREE L GORDON

ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MEMPHIS, TN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$4,797,577
FY 2025

Project Title

DIVINCI: Dissection of Influenza Vaccination and Infection for Childhood Immunity

Grant Number:

5U01AI144616-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/2/2019

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

SUMMARY Globally, influenza virus is a major public health burden. Evidence suggests that an individual’s earliest exposures to influenza have profound effects on immunity against the virus throughout life. Well-curated, infant cohorts, used to interrogate the full spectrum of immune responses again...

Research Terms

<0-11 years old><0-4 weeks old><Acylneuraminyl hydrolase><Address><Affect><Antibodies><Antibody Response><Antigens><Assay><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Bioassay><Biological Assay><Birth><Blood Banks><Blood Sample><Blood specimen><CD8><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CD8B><CD8B1><CD8B1 gene><Cell Body><Cells><Cellular Assay><Child><Child Youth><Childhood><Children (0-21)><Chronology><Clinical><Cohort Studies><Collaborations><Concurrent Studies><Development><Disease><Disorder><Disparate><Dissection><Elderly><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Flu vaccination><Grippe><Head><Hemagglutinin><History><Human><Immune><Immune memory><Immune response><Immune system><Immunes><Immunity><Immunochemical Immunologic><Immunologic><Immunologic Memory><Immunological><Immunological Memory><Immunologically><Immunologics><Individual><Infant><Infection><Influenza><Influenza Vaccines><Influenza Virus><Influenza immunization><Influenza vaccination><Investigation><Investigators><Joints><LYT3><Length of Life><Life><Long-term cohort><Longevity><Longitudinal cohort><Los Angeles><Mediating><Memory><Methods><Modern Man><N-Acylneuraminate Glycohydrolases><Neuraminidase><New Zealand><Newborn Infant><Newborns><Nicaragua><Nicaraguan><Oligosaccharide Sialidase><Parturition><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Predisposition><Productivity><Prophylactic vaccination against influenza><Protein Modification><Public Health><Publications><Receptor Protein><Recording of previous events><Recovery><Research><Research Personnel><Researchers><Sampling><Scientific Publication><Seasons><Serology><Sialidase><Site><Specificity><Susceptibility><T Cell Specificity><T cell response><T-Cell Immunologic Specificity><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><Testing><Vaccinated><Vaccination><Vaccines><Virus><advanced age><anamnestic reaction><anti-flu><anti-influenza><antiflu><cell assay><cohort><demographics><design><designing><developmental><enroll><epigenetically><exo alpha sialidase><experience><flu immunisation><flu infection><flu transmission><flu vaccine><flu virus infection><flu virus vaccine><geriatric><histories><host response><immune system response><immunogen><immunoresponse><imprint><improved><infected with flu><infected with flu virus><infected with influenza><infected with influenza virus><influenza infection><influenza transmission><influenza virus infection><influenza virus vaccination><influenza virus vaccine><influenzavirus><innovate><innovation><innovative><insight><kids><member><new vaccines><newborn child><newborn children><next generation vaccines><non vaccinated><not vaccinated><novel><novel vaccines><pediatric><programs><receptor><recruit><response><secondary immune response><senior citizen><thymus derived lymphocyte><transmission of the flu virus><unvaccinated><vaccination against influenza><vaccine against flu><vaccine against influenza><vaccine antibodies><vaccine effectiveness><vaccine induced antibodies><vaccine strategy><vaccine-induced antibodies><youngster>
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Paul G. Thomas

ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MEMPHIS, TN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$4,797,577
FY 2025

Project Title

DIVINCI: Dissection of Influenza Vaccination and Infection for Childhood Immunity

Grant Number:

5U01AI144616-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/2/2019

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

SUMMARY Globally, influenza virus is a major public health burden. Evidence suggests that an individual’s earliest exposures to influenza have profound effects on immunity against the virus throughout life. Well-curated, infant cohorts, used to interrogate the full spectrum of immune responses again...

Research Terms

<0-11 years old><0-4 weeks old><Acylneuraminyl hydrolase><Address><Affect><Antibodies><Antibody Response><Antigens><Assay><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Bioassay><Biological Assay><Birth><Blood Banks><Blood Sample><Blood specimen><CD8><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CD8B><CD8B1><CD8B1 gene><Cell Body><Cells><Cellular Assay><Child><Child Youth><Childhood><Children (0-21)><Chronology><Clinical><Cohort Studies><Collaborations><Concurrent Studies><Development><Disease><Disorder><Disparate><Dissection><Elderly><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Flu vaccination><Grippe><Head><Hemagglutinin><History><Human><Immune><Immune memory><Immune response><Immune system><Immunes><Immunity><Immunochemical Immunologic><Immunologic><Immunologic Memory><Immunological><Immunological Memory><Immunologically><Immunologics><Individual><Infant><Infection><Influenza><Influenza Vaccines><Influenza Virus><Influenza immunization><Influenza vaccination><Investigation><Investigators><Joints><LYT3><Length of Life><Life><Long-term cohort><Longevity><Longitudinal cohort><Los Angeles><Mediating><Memory><Methods><Modern Man><N-Acylneuraminate Glycohydrolases><Neuraminidase><New Zealand><Newborn Infant><Newborns><Nicaragua><Nicaraguan><Oligosaccharide Sialidase><Parturition><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Predisposition><Productivity><Prophylactic vaccination against influenza><Protein Modification><Public Health><Publications><Receptor Protein><Recording of previous events><Recovery><Research><Research Personnel><Researchers><Sampling><Scientific Publication><Seasons><Serology><Sialidase><Site><Specificity><Susceptibility><T Cell Specificity><T cell response><T-Cell Immunologic Specificity><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><Testing><Vaccinated><Vaccination><Vaccines><Virus><advanced age><anamnestic reaction><anti-flu><anti-influenza><antiflu><cell assay><cohort><demographics><design><designing><developmental><enroll><epigenetically><exo alpha sialidase><experience><flu immunisation><flu infection><flu transmission><flu vaccine><flu virus infection><flu virus vaccine><geriatric><histories><host response><immune system response><immunogen><immunoresponse><imprint><improved><infected with flu><infected with flu virus><infected with influenza><infected with influenza virus><influenza infection><influenza transmission><influenza virus infection><influenza virus vaccination><influenza virus vaccine><influenzavirus><innovate><innovation><innovative><insight><kids><member><new vaccines><newborn child><newborn children><next generation vaccines><non vaccinated><not vaccinated><novel><novel vaccines><pediatric><programs><receptor><recruit><response><secondary immune response><senior citizen><thymus derived lymphocyte><transmission of the flu virus><unvaccinated><vaccination against influenza><vaccine against flu><vaccine against influenza><vaccine antibodies><vaccine effectiveness><vaccine induced antibodies><vaccine strategy><vaccine-induced antibodies><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RICHARD John WEBBY

ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MEMPHIS, TN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$4,797,577
FY 2025

Project Title

DIVINCI: Dissection of Influenza Vaccination and Infection for Childhood Immunity

Grant Number:

5U01AI144616-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/2/2019

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

SUMMARY Globally, influenza virus is a major public health burden. Evidence suggests that an individual’s earliest exposures to influenza have profound effects on immunity against the virus throughout life. Well-curated, infant cohorts, used to interrogate the full spectrum of immune responses again...

Research Terms

<0-11 years old><0-4 weeks old><Acylneuraminyl hydrolase><Address><Affect><Antibodies><Antibody Response><Antigens><Assay><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Bioassay><Biological Assay><Birth><Blood Banks><Blood Sample><Blood specimen><CD8><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CD8B><CD8B1><CD8B1 gene><Cell Body><Cells><Cellular Assay><Child><Child Youth><Childhood><Children (0-21)><Chronology><Clinical><Cohort Studies><Collaborations><Concurrent Studies><Development><Disease><Disorder><Disparate><Dissection><Elderly><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Flu vaccination><Grippe><Head><Hemagglutinin><History><Human><Immune><Immune memory><Immune response><Immune system><Immunes><Immunity><Immunochemical Immunologic><Immunologic><Immunologic Memory><Immunological><Immunological Memory><Immunologically><Immunologics><Individual><Infant><Infection><Influenza><Influenza Vaccines><Influenza Virus><Influenza immunization><Influenza vaccination><Investigation><Investigators><Joints><LYT3><Length of Life><Life><Long-term cohort><Longevity><Longitudinal cohort><Los Angeles><Mediating><Memory><Methods><Modern Man><N-Acylneuraminate Glycohydrolases><Neuraminidase><New Zealand><Newborn Infant><Newborns><Nicaragua><Nicaraguan><Oligosaccharide Sialidase><Parturition><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Predisposition><Productivity><Prophylactic vaccination against influenza><Protein Modification><Public Health><Publications><Receptor Protein><Recording of previous events><Recovery><Research><Research Personnel><Researchers><Sampling><Scientific Publication><Seasons><Serology><Sialidase><Site><Specificity><Susceptibility><T Cell Specificity><T cell response><T-Cell Immunologic Specificity><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><Testing><Vaccinated><Vaccination><Vaccines><Virus><advanced age><anamnestic reaction><anti-flu><anti-influenza><antiflu><cell assay><cohort><demographics><design><designing><developmental><enroll><epigenetically><exo alpha sialidase><experience><flu immunisation><flu infection><flu transmission><flu vaccine><flu virus infection><flu virus vaccine><geriatric><histories><host response><immune system response><immunogen><immunoresponse><imprint><improved><infected with flu><infected with flu virus><infected with influenza><infected with influenza virus><influenza infection><influenza transmission><influenza virus infection><influenza virus vaccination><influenza virus vaccine><influenzavirus><innovate><innovation><innovative><insight><kids><member><new vaccines><newborn child><newborn children><next generation vaccines><non vaccinated><not vaccinated><novel><novel vaccines><pediatric><programs><receptor><recruit><response><secondary immune response><senior citizen><thymus derived lymphocyte><transmission of the flu virus><unvaccinated><vaccination against influenza><vaccine against flu><vaccine against influenza><vaccine antibodies><vaccine effectiveness><vaccine induced antibodies><vaccine strategy><vaccine-induced antibodies><youngster>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

George Gaitanaris

OMEROS CORPORATION, SEATTLE, WA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$4,461,636
FY 2025

Project Title

PDE7 Inhibitor for the Treatment of Cocaine Use Disorder

Grant Number:

5U01DA058541-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2023

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract The goal of this project is to advance to the clinic an oral drug candidate to treat cocaine use disorder (CUD). An estimated 1.3M persons in the US have CUD, and more than 19K people die each year from overdoses involving cocaine. There are no approved drug treatments for cocaine abuse. Mo...

Research Terms

<21+ years old><Acceleration><Address><Adult><Adult Human><Anesthesiology><Animal Model><Animal Models and Related Studies><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Brain region><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cessation of life><Chronic><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Cocaine><Cocaine Abuse><Cocaine Addiction><Cocaine Dependence><Cocaine use disorder><Common Rat Strains><Conditioning Therapy><Crab-Eating Macaque><Crab-Eating Monkey><Cynomolgus Monkey><Cynomolgus macaque><Data><Death><Development><Disease><Disorder><Dopamine><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Dropout><Drug Interactions><Drug Kinetics><Drug Therapy><Drug usage><Drugs><Early-Stage Clinical Trials><Effectiveness><Enzyme Gene><Enzymes><Exposure to><Future><Goals><Health Benefit><Heart Vascular><Human><Hydroxytyramine><Hypertension><IND Filing><IND application><IND package><IND submission><Individual><Inpatients><Intravenous><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Link><M fascicularis><M. fascicularis><Macaca cynomolgus><Macaca fascicularis><Macaca irus><Measures><Medical><Medication><Medicine><Modern Man><Nerve Transmitter Substances><Neurotransmitters><Oral><Outcome><Overdose><Pain><Painful><Persons><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Phase><Phase 1 Clinical Trials><Phase I Clinical Trials><Phosphodiesterases><Physiologic><Physiological><Placebos><Pre IND FDA meeting><Pre-IND mtg><Public Health><Randomized><Rat><Rats Mammals><Rattus><Relapse><Rewards><Safety><Sham Treatment><Specific qualifier value><Specified><Tachycardia><Testing><Therapeutic Agents><Toxicology><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Writing><abused drug><abused drugs><addicted to cocaine><addiction><addiction to cocaine><addictive disorder><adulthood><adverse consequence><adverse outcome><behavior intervention><behavioral intervention><circulatory system><cocaine addicted><cocaine craving><cocaine exposure><cocaine seeking><cocaine self-administration><cocaine use><cocaine-exposed><craving><developmental><dopamine system><drug abused><drug candidate><drug intervention><drug of abuse><drug treatment><drug use><drug withdrawal><drug/agent><drugs abused><drugs of abuse><effective therapy><effective treatment><exposed to cocaine><exposure to cocaine><extracellular><healthy volunteer><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><inhibitor><long-tailed macaque><meeting><meetings><model of animal><monoamine><non-human primate><nonhuman primate><novel><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><phase I protocol><phosphoric diester hydrolase><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><pre-clinical><preclinical><primary outcome><psychosocial><randomisation><randomization><randomly assigned><reuptake><safety study><safety testing><secondary outcome><self-administer cocaine><sham therapy><small molecule><volunteer>
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Xinhua Li

CLEAR SCIENTIFIC, LLC, CAMBRIDGE, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,799,875
FY 2025

Project Title

Clinical Development of a Therapeutic Agent for Rapid Reversal of Methamphetamine Intoxication

Grant Number:

5U01DA058548-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2023

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

1 PROJECT SUMMARY 2 There is an urgent need for a rapidly acting antidote for methamphetamine. Methamphetamine 3 (meth) is the fastest growing drug of abuse in the U.S., representing over 798,000 annual emergency department 4 (ED) visits, with deaths increasing 14-fold since 2015 (32,856 deaths i...

Research Terms

<Abscission><Acceleration><Accident and Emergency department><Achievement><Achievement Attainment><Acute><Address><Agreement><Antidotes><Binding><Biodistribution><Biological><Biological Markers><Blood><Blood Plasma><Blood Reticuloendothelial System><CNS Nervous System><Canine Species><Canis familiaris><Central Nervous System><Cessation of life><Chemistry><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Design><Common Rat Strains><Complex><Cross-Over Studies><Crossover Studies><Crystal Meth><Crystal methamphetamine><Death><Deoxyephedrine><Desoxyephedrine><Dogs><Dogs Mammals><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drug Kinetics><Drug Prescribing><Drug Prescriptions><Drug Stability><Drug usage><Drugs><ED visit><ER visit><Emergency Department><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room><Emergency room visit><Excision><Extirpation><Filtration><Filtration Fractionation><Food and Drug Administration><Formulation><Good Manufacturing Process><Good manufacturing practice><Guidelines><Half-Life><Hospitals><Human><Human Figure><Human body><IND Filing><IND application><IND package><IND submission><In Vitro><Individual><Intermediary Metabolism><International><Intoxication><Intravenous><Investigational New Drug Application><Kidney><Kidney Urinary System><Label><Ligands><Marketing><Medication><Metabolic Processes><Metabolism><Methamphetamine><Methamphetamine overdose><Methamphetamine use disorder><Methylamphetamine><Modern Man><Molecular Interaction><N-Methylamphetamine><Neuraxis><Outcome><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Study><Pharmacology><Pharmacology Study><Pharmacology and Toxicology><Phase><Phase 1a Trial><Phase 1b Clinical Trial><Phase 1b Trial><Phase Ia Trial><Phase Ib Clinical Trial><Phase Ib Trial><Placebo Control><Plasma><Plasma Serum><Pregnant Women><Preparation><Probability><Production><Randomized><Rat><Rats Mammals><Rattus><Receptor Protein><Recommendation><Removal><Research Resources><Resources><Reticuloendothelial System, Serum, Plasma><Rodent><Rodentia><Rodents Mammals><Safety><Sales><Saline><Saline Solution><Site><Surgical Removal><Therapeutic><Therapeutic Agents><Theriacs><Time><Toxic effect><Toxicities><Toxicology><USFDA><United States Food and Drug Administration><Urine><Vial><Vial device><Visit><abused drug><abused drugs><bio-markers><biologic><biologic marker><biomarker><canine><clinical development><determine efficacy><domestic dog><drug abused><drug of abuse><drug use><drug/agent><drugs abused><drugs of abuse><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><expectant mother><expectant women><expecting mother><expecting women><first in man><first-in-human><good laboratory practice><improved><in vivo><individuals who are pregnant><intravenous injection><manufacture><manufacturing process><medication prescription><meeting><meetings><meth><meth overdose><meth use disorder><new approaches><non-human primate><nonhuman primate><novel approaches><novel strategies><novel strategy><open label><open label study><patient oriented outcomes><people who are pregnant><phase 3 trial><phase III trial><placebo controlled><placebo controlled study><pregnant females><pregnant mothers><pregnant people><pregnant populations><preparations><prescribed medication><programs><randomisation><randomization><randomly assigned><receptor><renal><reproductive toxicity><resection><response><scale up><small molecule><success><those who are pregnant><women who are pregnant>
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Alan David Levine

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,215,234
FY 2025

Project Title

CWRU Center for Excellence on the Impact of Substance Use on HIV

Grant Number:

5P30DA054557-05

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/15/2021

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary - Overview The newly developed CWRU (Case Western Reserve University) Center for Excellence on the Impact of Substance Use on HIV was conceived in August 2017 and was initiated to effectively promote excellence in basic, translational, and clinical research concerning the intersecti...

Research Terms

<3-D modeling><3D modeling><AIDS><AIDS Virus><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Affect><Award><Basic Research><Basic Science><Behavioral><Behavioral Research><Bioinformatics><Biological Mimetics><Biometrics><Biometry><Biomimetics><Biostatistics><Body Tissues><Brain><Brain Nervous System><Business-Friendly Atmosphere><Cannabis><Capital><Caring><Cell Body><Cell model><Cells><Cellular model><Cities><Clinic><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Cocaine misuse><Communities><Community Outreach><Complex><Computational Biology><County><Crystal Meth><Crystal methamphetamine><Data Bases><Databases><Deoxyephedrine><Desoxyephedrine><Development><Diagnosis><Discipline><Disease><Disorder><Drug usage><Dysfunction><Education><Educational aspects><Encephalon><Equipment><Exposure to><Faculty><Faculty Education><Faculty Training><Foundations><Functional disorder><Funding><Grant><HCV co-infection><HCV coinfection><HCV/HIV><HIV><HIV and HCV><HIV and hepatitis C><HIV associated neurological disease><HIV associated neurological disorder><HIV-HCV><HIV/HCV><HIV/Hepatitis C><Health><Hepatitis C co-infection><Hospitals><Human Immunodeficiency Viruses><IQ Deficit><Immune><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infrastructure><International><Investigation><Investigators><LAV-HTLV-III><Leadership><Link><Lymphadenopathy-Associated Virus><METH use><Medical Directors><Medical center><Medicine><Memory Deficit><Memory impairment><Mental Health><Mental Hygiene><Mentors><Methamphetamine><Methods><Methylamphetamine><Modeling><Molecular><Motivation><Mucosa><Mucosal Tissue><Mucous Membrane><Myelogenous><Myeloid><N-Methylamphetamine><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Neurocognitive Deficit><Neurologic><Neurologic outcome><Neurological><Neurological outcome><Opiates><Opioid><Outcome><Pathogenesis><Patient Recruitments><Patients><Persons><Physician Executives><Physiopathology><Position><Positioning Attribute><Prevention Research><Prevention education><Process><Progenitor Cells><Proteomics><Psychological Health><Public Health><Reporting><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Risk><Rural><Schools><Services><Social Sciences><Strategic Planning><Substance Use Disorder><Survey Instrument><Surveys><Systems Biology><THC co-use><THC use><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Technology><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Tissues><Translational Research><Translational Science><Trauma><Underserved Population><United States Department of Veterans Affairs><United States Veterans Administration><Universities><University Hospitals><Veterans Administration><Veterans Affairs><Victimization><Violence><Virus-HIV><behavior outcome><behavioral health intervention><behavioral outcome><biobank><biorepository><business-friendly environment><cannabis use><career><clinical database><co-morbid><co-morbidity><cocaine use><cohort><collaborative atmosphere><collaborative environment><comorbidity><computer biology><conference><convention><data base><design><designing><developmental><drug use><experience><faculty development><faculty professional development><gastrointestinal><hepatitis C coinfection><hepatitis C virus co-infection><hepatitis C virus coinfection><iPS><iPSC><iPSC technology><iPSCs><immune reconstitution><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><immunosuppressive response><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cell technology><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><insight><instructor training><intelligence quotient deficit><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary collaboration><interdisciplinary environment><lecturer><lipidomics><marijuana use><medical college><medical schools><memory dysfunction><metabolism measurement><metabolomics><metabonomics><meth><methamphetamine use><microbiome><neural inflammation><neuro-AIDS><neuro-HIV><neuroAIDS><neuroHIV><neurocognitive decline><neurocognitive impairment><neuroinflammation><neuroinflammatory><new technology><next generation><novel technologies><opiate consumption><opiate drug use><opiate intake><opiate use><opioid consumption><opioid drug use><opioid intake><opioid use><participant recruitment><pathophysiology><peer-group atmosphere><peer-group environment><prevent violence><programs><school of medicine><service intervention><sex risk behavior><sexual risk behavior><stem cells><substance misuse><substance use><substance use and disorder><substance using><suburb><suburban><suburbia><summit><symposia><symposium><synergism><teacher development><three-dimensional modeling><transcriptomics><transdisciplinary collaboration><translation research><translational investigation><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><violence prevention><violent><violent behavior>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nicholas David Cosford

SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, LA JOLLA, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,652,771
FY 2025

Project Title

Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in Smokers

Grant Number:

5U01DA057847-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2023

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY This resubmission application, “Safety/toxicology, ADME and CMC activities to support the assessment of the mGlu2 PAM SBP-9330 in a Phase 2 clinical study in smokers”, is in response to PAR-22-202 and represents the continuation of our current work funded through 07/31/2023 by U01 DA...

Research Terms

<21+ years old><ADME Study><Abnormal Assessment of Metabolism><Absorption, Distribution, Metabolism, and Excretion Study><Abstinence><Achievement><Achievement Attainment><Acute><Adult><Adult Human><Adverse Experience><Adverse event><Amfebutamone><Animal Model><Animal Models and Related Studies><Applications Grants><Autoradiography><Bioavailability><Biological Availability><Blood Plasma><Body System><Brain><Brain Nervous System><Bupropion><Canine Species><Canis familiaris><Categories><Cause of Death><Cessation of life><Chemistry><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Common Rat Strains><Cues><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 Family Gene><Data><Death><Development><Disease><Disorder><Dogs><Dogs Mammals><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drug Kinetics><Drug or chemical Tissue Distribution><Drug usage><Drugs><Encephalon><Evaluation><Excretory function><Food and Drug Administration><Funding><Gastrointestinal Diseases><Glutamates><Good Manufacturing Process><Good manufacturing practice><Grant><Grant Proposals><Hepatic><Human><Intermediary Metabolism><Investigation><Investigational Drugs><Investigational New Drugs><Investigators><Kidney><Kidney Urinary System><L-Glutamate><Label><Measures><Medication><Metabolic><Metabolic Processes><Metabolic Studies><Metabolism><Metabolism Studies><Metabotropic Glutamate Receptors><Modern Man><Morbidity><Morbidity - disease rate><Nerve Impulse Transmission><Nerve Transmission><Nervous System Diseases><Nervous System Disorder><Neurologic Disorders><Neurological Disorders><Neuronal Transmission><Nicotine><Nicotine Dependence><Nicotine Replacement Therapy><Nicotinic Agents><Oral><Organ System><P450><Passive Smoke Exposure><Penetration><Pharmaceutical Preparations><Pharmacokinetics><Phase><Phase I Study><Physiologic Availability><Placebo Control><Plasma><Plasma Serum><Prevalence><Productivity><Property><Qualifying><Radioautography><Randomized><Rat><Rats Mammals><Rattus><Receptor Protein><Research><Research Personnel><Researchers><Reticuloendothelial System, Serum, Plasma><Safety><Series><Serious Adverse Event><Severe Adverse Event><Severities><Smoker><Smoking><Substance Use Disorder><Testing><Therapeutic Agents><Time><Tissue Distribution><Toxic effect><Toxicities><Toxicology><USFDA><United States><United States Food and Drug Administration><Wellbutrin><Work><absorption><adulthood><axon signaling><axon-glial signaling><axonal signaling><buproprion><canine><cease smoking><cigarette smoking><cigarette use><clinical development><cohort><design><designing><developmental><domestic dog><drug reinforcement><drug use><drug/agent><environmental tobacco smoke exposure><excretion><experience><exposure to ETS><exposure to SHS><exposure to environmental tobacco smoke><exposure to secondhand smoke><exposure to tobacco smoke><gastrointestinal disorder><glia signaling><glial signaling><glutamatergic><good laboratory practice><in vitro Assay><manufacture><metabolic abnormality assessment><model of animal><mortality><multidisciplinary><nerve signaling><neural signaling><neurological disease><neuronal signaling><neurotransmission><new drug class><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><nicotine addiction><nicotine cessation><nicotine dependent><nicotine replacement><nicotine seeking><nicotine seeking behavior><nicotine self-administration><nicotine treatment><non-smoker><nonsmoker><novel drug class><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><phase 1 study><phase 2 study><phase II study><placebo controlled><positive allosteric modulator><pre-clinical><preclinical><prevent relapse><quit smoking><randomisation><randomization><randomly assigned><receptor><relapse prevention><renal><response><second hand smoke exposure><secondhand smoke exposure><secondhand tobacco smoke exposure><serious adverse experience><serious adverse reaction><small molecule><smoking cessation><statistics><stop smoking><substance use and disorder><success><therapeutically effective><tobacco smokers><tobacco user><varenicline>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Benjamin s McKenna

SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, LA JOLLA, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,652,771
FY 2025

Project Title

Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in Smokers

Grant Number:

5U01DA057847-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2023

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY This resubmission application, “Safety/toxicology, ADME and CMC activities to support the assessment of the mGlu2 PAM SBP-9330 in a Phase 2 clinical study in smokers”, is in response to PAR-22-202 and represents the continuation of our current work funded through 07/31/2023 by U01 DA...

Research Terms

<21+ years old><ADME Study><Abnormal Assessment of Metabolism><Absorption, Distribution, Metabolism, and Excretion Study><Abstinence><Achievement><Achievement Attainment><Acute><Adult><Adult Human><Adverse Experience><Adverse event><Amfebutamone><Animal Model><Animal Models and Related Studies><Applications Grants><Autoradiography><Bioavailability><Biological Availability><Blood Plasma><Body System><Brain><Brain Nervous System><Bupropion><Canine Species><Canis familiaris><Categories><Cause of Death><Cessation of life><Chemistry><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Common Rat Strains><Cues><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 Family Gene><Data><Death><Development><Disease><Disorder><Dogs><Dogs Mammals><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drug Kinetics><Drug or chemical Tissue Distribution><Drug usage><Drugs><Encephalon><Evaluation><Excretory function><Food and Drug Administration><Funding><Gastrointestinal Diseases><Glutamates><Good Manufacturing Process><Good manufacturing practice><Grant><Grant Proposals><Hepatic><Human><Intermediary Metabolism><Investigation><Investigational Drugs><Investigational New Drugs><Investigators><Kidney><Kidney Urinary System><L-Glutamate><Label><Measures><Medication><Metabolic><Metabolic Processes><Metabolic Studies><Metabolism><Metabolism Studies><Metabotropic Glutamate Receptors><Modern Man><Morbidity><Morbidity - disease rate><Nerve Impulse Transmission><Nerve Transmission><Nervous System Diseases><Nervous System Disorder><Neurologic Disorders><Neurological Disorders><Neuronal Transmission><Nicotine><Nicotine Dependence><Nicotine Replacement Therapy><Nicotinic Agents><Oral><Organ System><P450><Passive Smoke Exposure><Penetration><Pharmaceutical Preparations><Pharmacokinetics><Phase><Phase I Study><Physiologic Availability><Placebo Control><Plasma><Plasma Serum><Prevalence><Productivity><Property><Qualifying><Radioautography><Randomized><Rat><Rats Mammals><Rattus><Receptor Protein><Research><Research Personnel><Researchers><Reticuloendothelial System, Serum, Plasma><Safety><Series><Serious Adverse Event><Severe Adverse Event><Severities><Smoker><Smoking><Substance Use Disorder><Testing><Therapeutic Agents><Time><Tissue Distribution><Toxic effect><Toxicities><Toxicology><USFDA><United States><United States Food and Drug Administration><Wellbutrin><Work><absorption><adulthood><axon signaling><axon-glial signaling><axonal signaling><buproprion><canine><cease smoking><cigarette smoking><cigarette use><clinical development><cohort><design><designing><developmental><domestic dog><drug reinforcement><drug use><drug/agent><environmental tobacco smoke exposure><excretion><experience><exposure to ETS><exposure to SHS><exposure to environmental tobacco smoke><exposure to secondhand smoke><exposure to tobacco smoke><gastrointestinal disorder><glia signaling><glial signaling><glutamatergic><good laboratory practice><in vitro Assay><manufacture><metabolic abnormality assessment><model of animal><mortality><multidisciplinary><nerve signaling><neural signaling><neurological disease><neuronal signaling><neurotransmission><new drug class><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><nicotine addiction><nicotine cessation><nicotine dependent><nicotine replacement><nicotine seeking><nicotine seeking behavior><nicotine self-administration><nicotine treatment><non-smoker><nonsmoker><novel drug class><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><phase 1 study><phase 2 study><phase II study><placebo controlled><positive allosteric modulator><pre-clinical><preclinical><prevent relapse><quit smoking><randomisation><randomization><randomly assigned><receptor><relapse prevention><renal><response><second hand smoke exposure><secondhand smoke exposure><secondhand tobacco smoke exposure><serious adverse experience><serious adverse reaction><small molecule><smoking cessation><statistics><stop smoking><substance use and disorder><success><therapeutically effective><tobacco smokers><tobacco user><varenicline>
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Gonul Velicelebi

SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, LA JOLLA, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,652,771
FY 2025

Project Title

Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in Smokers

Grant Number:

5U01DA057847-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2023

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY This resubmission application, “Safety/toxicology, ADME and CMC activities to support the assessment of the mGlu2 PAM SBP-9330 in a Phase 2 clinical study in smokers”, is in response to PAR-22-202 and represents the continuation of our current work funded through 07/31/2023 by U01 DA...

Research Terms

<21+ years old><ADME Study><Abnormal Assessment of Metabolism><Absorption, Distribution, Metabolism, and Excretion Study><Abstinence><Achievement><Achievement Attainment><Acute><Adult><Adult Human><Adverse Experience><Adverse event><Amfebutamone><Animal Model><Animal Models and Related Studies><Applications Grants><Autoradiography><Bioavailability><Biological Availability><Blood Plasma><Body System><Brain><Brain Nervous System><Bupropion><Canine Species><Canis familiaris><Categories><Cause of Death><Cessation of life><Chemistry><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Common Rat Strains><Cues><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 Family Gene><Data><Death><Development><Disease><Disorder><Dogs><Dogs Mammals><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drug Kinetics><Drug or chemical Tissue Distribution><Drug usage><Drugs><Encephalon><Evaluation><Excretory function><Food and Drug Administration><Funding><Gastrointestinal Diseases><Glutamates><Good Manufacturing Process><Good manufacturing practice><Grant><Grant Proposals><Hepatic><Human><Intermediary Metabolism><Investigation><Investigational Drugs><Investigational New Drugs><Investigators><Kidney><Kidney Urinary System><L-Glutamate><Label><Measures><Medication><Metabolic><Metabolic Processes><Metabolic Studies><Metabolism><Metabolism Studies><Metabotropic Glutamate Receptors><Modern Man><Morbidity><Morbidity - disease rate><Nerve Impulse Transmission><Nerve Transmission><Nervous System Diseases><Nervous System Disorder><Neurologic Disorders><Neurological Disorders><Neuronal Transmission><Nicotine><Nicotine Dependence><Nicotine Replacement Therapy><Nicotinic Agents><Oral><Organ System><P450><Passive Smoke Exposure><Penetration><Pharmaceutical Preparations><Pharmacokinetics><Phase><Phase I Study><Physiologic Availability><Placebo Control><Plasma><Plasma Serum><Prevalence><Productivity><Property><Qualifying><Radioautography><Randomized><Rat><Rats Mammals><Rattus><Receptor Protein><Research><Research Personnel><Researchers><Reticuloendothelial System, Serum, Plasma><Safety><Series><Serious Adverse Event><Severe Adverse Event><Severities><Smoker><Smoking><Substance Use Disorder><Testing><Therapeutic Agents><Time><Tissue Distribution><Toxic effect><Toxicities><Toxicology><USFDA><United States><United States Food and Drug Administration><Wellbutrin><Work><absorption><adulthood><axon signaling><axon-glial signaling><axonal signaling><buproprion><canine><cease smoking><cigarette smoking><cigarette use><clinical development><cohort><design><designing><developmental><domestic dog><drug reinforcement><drug use><drug/agent><environmental tobacco smoke exposure><excretion><experience><exposure to ETS><exposure to SHS><exposure to environmental tobacco smoke><exposure to secondhand smoke><exposure to tobacco smoke><gastrointestinal disorder><glia signaling><glial signaling><glutamatergic><good laboratory practice><in vitro Assay><manufacture><metabolic abnormality assessment><model of animal><mortality><multidisciplinary><nerve signaling><neural signaling><neurological disease><neuronal signaling><neurotransmission><new drug class><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><nicotine addiction><nicotine cessation><nicotine dependent><nicotine replacement><nicotine seeking><nicotine seeking behavior><nicotine self-administration><nicotine treatment><non-smoker><nonsmoker><novel drug class><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><phase 1 study><phase 2 study><phase II study><placebo controlled><positive allosteric modulator><pre-clinical><preclinical><prevent relapse><quit smoking><randomisation><randomization><randomly assigned><receptor><relapse prevention><renal><response><second hand smoke exposure><secondhand smoke exposure><secondhand tobacco smoke exposure><serious adverse experience><serious adverse reaction><small molecule><smoking cessation><statistics><stop smoking><substance use and disorder><success><therapeutically effective><tobacco smokers><tobacco user><varenicline>
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STEPHEN GERARD KALER

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,522,499
FY 2025

Project Title

Viral Gene Therapy for Menkes Disease

Grant Number:

5U01NS129343-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2023

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

URGenT Network U01 proposal will evaluate the preclinical safety, tolerability, and dosing of AAV9-codon-optimized, reduced-size ATP7A, which we propose to use in a first-in-human clinical trial for Menkes disease. Menkes disease is a X-linked recessive infantile-onset neurodegenerative disorder of ...

Research Terms

<0-11 years old><Affect><Age><Animals><Appearance><Aran-Duchenne disease><Biochemical><Biodistribution><Biologic Sciences><Biological Agent><Biological Products><Biological Sciences><Bioscience><Birth><Body Weight><Budgets><Capsid><Cessation of life><Child><Child Youth><Childhood><Children (0-21)><Children's Hospital><Clinical><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Design><Codon><Codon Nucleotides><Combined Modality Therapy><Complement><Complement Proteins><Congenital Hypocupremia><Copper><Cruveilhier disease><Cu element><Cyclic GMP><DNA Therapy><DNA mutation><Data><Death><Degenerative Neurologic Disorders><Developmental Therapeutics><Developmental Therapeutics Program><Developmental Therapy><Direct Costs><Disease><Disorder><Dorsal Root Ganglia><Dose><Drug Kinetics><Enrollment><FDA approved><Facial Vein><Facial vein structure><Factor VIII Deficiency><Feedback><Future><Gene Transfer Clinical><GeneHomolog><Genes><Genetic Change><Genetic Intervention><Genetic defect><Genetic mutation><Guanosine Cyclic Monophosphate><Hemophilia><Hemophilia A><Hereditary><Hereditary Disease><Histopathology><Homolog><Homologous Gene><Homologue><Human><Human Development><Inborn Genetic Diseases><Incidence><Infant><Inherited><Inherited disorder><Injections><Innate Immune Response><Intermediary Metabolism><Intravenous><Kinky Hair Disease><Kinky Hair Syndrome><Knowledge><Label><Laboratories><Laboratory Research><Licensing><Life><Life Sciences><Mediating><Medulla Spinalis><Menkes Kinky Hair Syndrome><Menkes Syndrome><Menkes disease><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modern Man><Molecular><Multimodal Therapy><Multimodal Treatment><Murine><Mus><Mutant Strains Mice><Mutation><NGS Method><NGS system><NIH><NINDS><National Institute of Neurological Diseases and Stroke><National Institute of Neurological Disorders and Stroke><National Institutes of Health><Natural History><Neonatal Screening><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic><Neurologic Degenerative Conditions><Neurologic Manifestations><Neurologic Signs and Symptoms><Neurologic Symptoms><Neurological><Neurological Manifestations><Neurological Signs and Symptoms><New Drug Approvals><New York><Newborn Infant Screening><Outcome><Parturition><Pediatric Hospitals><Peripheral Nerves><Pharmacokinetics><Phase><Phase 1/2 Clinical Trial><Phase I/II Clinical Trial><Pilot Projects><Plasmids><Pre IND FDA meeting><Pre-IND mtg><Qualifying><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Recombinants><Recommendation><Regimen><Research><Research Grants><Research Project Grants><Research Projects><Residual><Residual state><Safety><Series><Spinal Cord><Spinal Ganglia><Spinal Muscular Atrophy><Steely Hair Disease><Steely Hair Syndrome><Technology><Therapeutic><Time><Toxicology><Transgenes><Tropism><United States National Institutes of Health><Variant><Variation><Viral><Viral Genes><Work><X-linked copper malabsorption><ages><animal safety><beneficiary><biologics><biopharmaceutical><biotherapeutic agent><cGMP><combination therapy><combined modality treatment><combined treatment><complementation><congenital hypocupraemia syndrome><copper-transporting ATPase><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><dorsal root ganglion><enroll><entire genome><experience><first in man><first-in-human><full genome><gene repair therapy><gene therapy><gene-based therapy><genetic therapy><genome mutation><genome sequencing><genomic therapy><hereditary disorder><heritable disorder><human subject><improved><inborn error><infancy><infantile><inherited diseases><inherited genetic disease><inherited genetic disorder><innovate><innovation><innovative><interest><kids><loss of function><male><manufacture><mortality><mouse model><mouse mutant><multi-modal therapy><multi-modal treatment><murine model><neural manifestation><neurodegenerative illness><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><newborn screening><next gen sequencing><next generation sequencing><next generation therapeutics><nextgen sequencing><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><pediatric><pilot study><population based><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><pre-clinical><pre-clinical safety><pre-clinical study><preclinical><preclinical safety><preclinical study><premature><prematurity><prospective><randomisation><randomization><randomly assigned><response><sex linked recessive><small molecule><subcutaneous><subdermal><success><transgene><trichopoliodystrophy><vector><whole genome><x-linked recessive><youngster><♂>
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Bradley F Boeve

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,340,234
FY 2025

Project Title

Longitudinal Imaging Biomarkers of Prodromal DLB

Grant Number:

5U01NS100620-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY / ABSTRACT Mild Cognitive Impairment (MCI) with core clinical features of dementia with Lewy bodies (DLB) is recognized as the prodromal stage of DLB (MCI-LB). Patients with MCI-LB frequently progress to DLB, but a subset may have a range of additional AD pathology. Rapid advances in...

Research Terms

<3-D><3-Dimensional><3D><AD dementia><AD pathology><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's disease pathology><Alzheimer's pathology><Alzheimers Dementia><Amentia><Assay><Attention><Autopsy><Bioassay><Biological Assay><Biological Markers><Body Tissues><Brain Vascular Disorders><Cerebrovascular Disease><Cerebrovascular Disorders><Clinic><Clinical><Clinical Trials><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><DAT dopamine transporter><Data><Dementia><Dementia with Lewy Bodies><Development><Diagnosis><Disease><Disease Progression><Disorder><Disturbance in cognition><Evolution><Florida><Goals><Guidelines><Image><Impaired cognition><Individual><Intracranial Vascular Diseases><Intracranial Vascular Disorders><Investigation><Investigators><LB disease><LB disorder><Lesion><Lewy Body Disease><Lewy body disorder><Lewy disease><Lewy disorder><Life><MR Imaging><MR Tomography><MRI><MRI biomarker><MRI marker><MRIs><Magnetic Resonance Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Memory><Multimodal Imaging><NAC precursor><NMR Imaging><NMR Tomography><Names><Nuclear Magnetic Resonance Imaging><Outcome><PARK1 protein><PARK4 protein><PET><PET Scan><PET imaging><PETSCAN><PETT><Paralysis Agitans><Parkinson><Parkinson Disease><Participant><Pathologic><Pathology><Patients><Phase><Phenotype><Pittsburgh Compound-B><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Predicting Risk><Preparation><Primary Parkinsonism><Primary Senile Degenerative Dementia><Probability><Process><Progress Reports><Proteins><Rad.-PET><Research Personnel><Researchers><SNCA><SNCA protein><SPECT><SPECT imaging><Sampling><Single-Photon Emission-Computed Radionuclide Tomography><Site><Specificity><Syndrome><Time><Tissues><Zeugmatography><a-syn><a-synuclein><ages><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><bio-markers><biologic marker><biological sex as a modifier><biomarker><biomarker identification><biomarker selection><brain vascular disease><brain vascular dysfunction><cerebral vascular disease><cerebral vascular dysfunction><cerebrovascular dysfunction><cognitive dysfunction><cognitive loss><design><designing><developmental><dopamine transporter><forecasting risk><identification of biomarkers><identification of new biomarkers><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><intracranial vascular dysfunction><ligand PIB><longitudinal imaging><magnetic resonance imaging biomarker><magnetic resonance imaging marker><marker identification><mild cognitive disorder><mild cognitive impairment><multi-modal imaging><multi-modality><multi-modality imaging><multidisciplinary><multimodality><multimodality imaging><name><named><naming><necropsy><new marker><non A-beta component of AD amyloid><non A4 component of amyloid precursor><novel biomarker><novel marker><patient population><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><predictive risk><predicts risk><preparations><prevent><preventing><primary degenerative dementia><programs><progression risk><protein misfolding cyclic amplification><response to therapy><response to treatment><risk prediction><risk predictions><senile dementia of the Alzheimer type><serial imaging><sex as a biological factor><sex as a biological measure><sex as a biological risk factor><sex as a biological variable><sex as a biological variance><sex as a biologically significant variable><sex as a fundamental variable><single photon emission computed tomography><stem><therapeutic response><therapy response><three dimensional><treatment response><treatment responsiveness><visual process><visual processing><α synuclein gene><α-syn><α-synuclein>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KEJAL KANTARCI

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,340,234
FY 2025

Project Title

Longitudinal Imaging Biomarkers of Prodromal DLB

Grant Number:

5U01NS100620-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY / ABSTRACT Mild Cognitive Impairment (MCI) with core clinical features of dementia with Lewy bodies (DLB) is recognized as the prodromal stage of DLB (MCI-LB). Patients with MCI-LB frequently progress to DLB, but a subset may have a range of additional AD pathology. Rapid advances in...

Research Terms

<3-D><3-Dimensional><3D><AD dementia><AD pathology><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's disease pathology><Alzheimer's pathology><Alzheimers Dementia><Amentia><Assay><Attention><Autopsy><Bioassay><Biological Assay><Biological Markers><Body Tissues><Brain Vascular Disorders><Cerebrovascular Disease><Cerebrovascular Disorders><Clinic><Clinical><Clinical Trials><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><DAT dopamine transporter><Data><Dementia><Dementia with Lewy Bodies><Development><Diagnosis><Disease><Disease Progression><Disorder><Disturbance in cognition><Evolution><Florida><Goals><Guidelines><Image><Impaired cognition><Individual><Intracranial Vascular Diseases><Intracranial Vascular Disorders><Investigation><Investigators><LB disease><LB disorder><Lesion><Lewy Body Disease><Lewy body disorder><Lewy disease><Lewy disorder><Life><MR Imaging><MR Tomography><MRI><MRI biomarker><MRI marker><MRIs><Magnetic Resonance Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Memory><Multimodal Imaging><NAC precursor><NMR Imaging><NMR Tomography><Names><Nuclear Magnetic Resonance Imaging><Outcome><PARK1 protein><PARK4 protein><PET><PET Scan><PET imaging><PETSCAN><PETT><Paralysis Agitans><Parkinson><Parkinson Disease><Participant><Pathologic><Pathology><Patients><Phase><Phenotype><Pittsburgh Compound-B><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Predicting Risk><Preparation><Primary Parkinsonism><Primary Senile Degenerative Dementia><Probability><Process><Progress Reports><Proteins><Rad.-PET><Research Personnel><Researchers><SNCA><SNCA protein><SPECT><SPECT imaging><Sampling><Single-Photon Emission-Computed Radionuclide Tomography><Site><Specificity><Syndrome><Time><Tissues><Zeugmatography><a-syn><a-synuclein><ages><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><bio-markers><biologic marker><biological sex as a modifier><biomarker><biomarker identification><biomarker selection><brain vascular disease><brain vascular dysfunction><cerebral vascular disease><cerebral vascular dysfunction><cerebrovascular dysfunction><cognitive dysfunction><cognitive loss><design><designing><developmental><dopamine transporter><forecasting risk><identification of biomarkers><identification of new biomarkers><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><intracranial vascular dysfunction><ligand PIB><longitudinal imaging><magnetic resonance imaging biomarker><magnetic resonance imaging marker><marker identification><mild cognitive disorder><mild cognitive impairment><multi-modal imaging><multi-modality><multi-modality imaging><multidisciplinary><multimodality><multimodality imaging><name><named><naming><necropsy><new marker><non A-beta component of AD amyloid><non A4 component of amyloid precursor><novel biomarker><novel marker><patient population><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><predictive risk><predicts risk><preparations><prevent><preventing><primary degenerative dementia><programs><progression risk><protein misfolding cyclic amplification><response to therapy><response to treatment><risk prediction><risk predictions><senile dementia of the Alzheimer type><serial imaging><sex as a biological factor><sex as a biological measure><sex as a biological risk factor><sex as a biological variable><sex as a biological variance><sex as a biologically significant variable><sex as a fundamental variable><single photon emission computed tomography><stem><therapeutic response><therapy response><three dimensional><treatment response><treatment responsiveness><visual process><visual processing><α synuclein gene><α-syn><α-synuclein>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Arin M Connell

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,320,210
FY 2025

Project Title

Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodology

Grant Number:

5U01MH137067-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/9/2024

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The goal of this application, submitted in response to RFA-MH-23-275, “Using Secondary Data Analysis to Determine Whether Preventive Interventions Implemented Earlier in Life Reduce Suicide Risk,” is to conduct research that will integrate and harmonize existing large prevention trial datasets. The ...

Research Terms

<0-11 years old><21+ years old><Accidents><Address><Adult><Adult Human><Age><Archives><Area><Automobile Driving><Behavior><Behavioral><Cell Communication and Signaling><Cell Signaling><Cessation of life><Characteristics><Check-up><Child><Child Rearing><Child Youth><Children (0-21)><Collaborations><Communities><Complex><Consent><Cooperative Agreements><Data><Data Analyses><Data Analysis><Data Set><Death><Deposit><Deposition><Detection><Development><Diagnosis><Distal><Documentation><Dose><Drug usage><Early Trauma><Early-life trauma><Effectiveness of Interventions><Elements><Emotional><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Exposure to><Family><Family Nursing><Family-Centered Nursing><Feeling suicidal><Funding><Future><Gender><Gender and Sexual Minorities><Generalized Growth><Geography><Goals><Growth><Heterogeneity><Individual><Intervention><Intervention Strategies><Intracellular Communication and Signaling><Junior High School Student><Junior High Student><Life><Link><Measures><Mediator><Methodology><Middle School Student><Minority><Modeling><NIMH><National Institute of Mental Health><Outcome><Overdose><Parenting><Parenting behavior><Participant><Population><Preparation><Preventative intervention><Preventative strategy><Prevention><Prevention program><Prevention strategy><Prevention trial><Preventive><Preventive strategy><Principal Investigator><Racial Group><Randomized, Controlled Trials><Regulation><Reporting><Research><Research Resources><Resources><Rights><Risk><Risk Reduction><Rural><Schools><Sex Orientation><Sexual Orientation><Sexual and Gender Minorities><Signal Transduction><Signal Transduction Systems><Signaling><Social Development><Social support><Socioeconomically disadvantaged><Substance Use Disorder><Suicidal thoughts><Suicide><Symptoms><System><Techniques><Tissue Growth><U-Series Cooperative Agreements><United States><Work><Youth><Youth 10-21><adulthood><adverse childhood events><adverse childhood experiences><ages><biological signal transduction><checkup><checkup examination><childrearing><coping><data archive><data archives><data dictionary><data harmonization><data interpretation><dating violence><developmental><deviant peer><disadvantaged background><driving><drug use><early childhood><early experience><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><ethnic subgroup><ethnicity group><evidence base><experience><fatal attempt><fatal suicide><foster care><harmonized data><indexing><intent to die><interest><intervention for prevention><kids><marginalized background><methods to study multiple-level influences><mortality><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><ontogeny><opiate use disorder><opioid use disorder><preparations><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><racial minority group><racial minority individual><racial minority people><racial minority population><racial population><racial subgroup><randomized control trial><randomized, clinical trials><reduce risk><reduce risks><reduce suicidality><reduce suicide><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing suicidality><reducing suicide><reducing the risk><response><risk-reducing><sexual minority adolescent><sexual minority children><sexual minority youth><social><social factors><social support network><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><substance use and disorder><suburb><suburban><suburbia><suicidal behavior><suicidal ideation><suicidal morbidity><suicidal risk><suicidal thinking><suicide behavior><suicide death><suicide ideation><suicide morbidity><suicide risk><suicides><teacher><thoughts about suicide><treatment effect><universal interventions><universal prevention><universal preventive interventions><universal preventive measure><youngster><youth age>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marina Epstein

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,320,210
FY 2025

Project Title

Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodology

Grant Number:

5U01MH137067-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/9/2024

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The goal of this application, submitted in response to RFA-MH-23-275, “Using Secondary Data Analysis to Determine Whether Preventive Interventions Implemented Earlier in Life Reduce Suicide Risk,” is to conduct research that will integrate and harmonize existing large prevention trial datasets. The ...

Research Terms

<0-11 years old><21+ years old><Accidents><Address><Adult><Adult Human><Age><Archives><Area><Automobile Driving><Behavior><Behavioral><Cell Communication and Signaling><Cell Signaling><Cessation of life><Characteristics><Check-up><Child><Child Rearing><Child Youth><Children (0-21)><Collaborations><Communities><Complex><Consent><Cooperative Agreements><Data><Data Analyses><Data Analysis><Data Set><Death><Deposit><Deposition><Detection><Development><Diagnosis><Distal><Documentation><Dose><Drug usage><Early Trauma><Early-life trauma><Effectiveness of Interventions><Elements><Emotional><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Exposure to><Family><Family Nursing><Family-Centered Nursing><Feeling suicidal><Funding><Future><Gender><Gender and Sexual Minorities><Generalized Growth><Geography><Goals><Growth><Heterogeneity><Individual><Intervention><Intervention Strategies><Intracellular Communication and Signaling><Junior High School Student><Junior High Student><Life><Link><Measures><Mediator><Methodology><Middle School Student><Minority><Modeling><NIMH><National Institute of Mental Health><Outcome><Overdose><Parenting><Parenting behavior><Participant><Population><Preparation><Preventative intervention><Preventative strategy><Prevention><Prevention program><Prevention strategy><Prevention trial><Preventive><Preventive strategy><Principal Investigator><Racial Group><Randomized, Controlled Trials><Regulation><Reporting><Research><Research Resources><Resources><Rights><Risk><Risk Reduction><Rural><Schools><Sex Orientation><Sexual Orientation><Sexual and Gender Minorities><Signal Transduction><Signal Transduction Systems><Signaling><Social Development><Social support><Socioeconomically disadvantaged><Substance Use Disorder><Suicidal thoughts><Suicide><Symptoms><System><Techniques><Tissue Growth><U-Series Cooperative Agreements><United States><Work><Youth><Youth 10-21><adulthood><adverse childhood events><adverse childhood experiences><ages><biological signal transduction><checkup><checkup examination><childrearing><coping><data archive><data archives><data dictionary><data harmonization><data interpretation><dating violence><developmental><deviant peer><disadvantaged background><driving><drug use><early childhood><early experience><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><ethnic subgroup><ethnicity group><evidence base><experience><fatal attempt><fatal suicide><foster care><harmonized data><indexing><intent to die><interest><intervention for prevention><kids><marginalized background><methods to study multiple-level influences><mortality><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><ontogeny><opiate use disorder><opioid use disorder><preparations><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><racial minority group><racial minority individual><racial minority people><racial minority population><racial population><racial subgroup><randomized control trial><randomized, clinical trials><reduce risk><reduce risks><reduce suicidality><reduce suicide><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing suicidality><reducing suicide><reducing the risk><response><risk-reducing><sexual minority adolescent><sexual minority children><sexual minority youth><social><social factors><social support network><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><substance use and disorder><suburb><suburban><suburbia><suicidal behavior><suicidal ideation><suicidal morbidity><suicidal risk><suicidal thinking><suicide behavior><suicide death><suicide ideation><suicide morbidity><suicide risk><suicides><teacher><thoughts about suicide><treatment effect><universal interventions><universal prevention><universal preventive interventions><universal preventive measure><youngster><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ANTONIO A MORGAN-LOPEZ

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,320,210
FY 2025

Project Title

Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodology

Grant Number:

5U01MH137067-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/9/2024

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The goal of this application, submitted in response to RFA-MH-23-275, “Using Secondary Data Analysis to Determine Whether Preventive Interventions Implemented Earlier in Life Reduce Suicide Risk,” is to conduct research that will integrate and harmonize existing large prevention trial datasets. The ...

Research Terms

<0-11 years old><21+ years old><Accidents><Address><Adult><Adult Human><Age><Archives><Area><Automobile Driving><Behavior><Behavioral><Cell Communication and Signaling><Cell Signaling><Cessation of life><Characteristics><Check-up><Child><Child Rearing><Child Youth><Children (0-21)><Collaborations><Communities><Complex><Consent><Cooperative Agreements><Data><Data Analyses><Data Analysis><Data Set><Death><Deposit><Deposition><Detection><Development><Diagnosis><Distal><Documentation><Dose><Drug usage><Early Trauma><Early-life trauma><Effectiveness of Interventions><Elements><Emotional><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Exposure to><Family><Family Nursing><Family-Centered Nursing><Feeling suicidal><Funding><Future><Gender><Gender and Sexual Minorities><Generalized Growth><Geography><Goals><Growth><Heterogeneity><Individual><Intervention><Intervention Strategies><Intracellular Communication and Signaling><Junior High School Student><Junior High Student><Life><Link><Measures><Mediator><Methodology><Middle School Student><Minority><Modeling><NIMH><National Institute of Mental Health><Outcome><Overdose><Parenting><Parenting behavior><Participant><Population><Preparation><Preventative intervention><Preventative strategy><Prevention><Prevention program><Prevention strategy><Prevention trial><Preventive><Preventive strategy><Principal Investigator><Racial Group><Randomized, Controlled Trials><Regulation><Reporting><Research><Research Resources><Resources><Rights><Risk><Risk Reduction><Rural><Schools><Sex Orientation><Sexual Orientation><Sexual and Gender Minorities><Signal Transduction><Signal Transduction Systems><Signaling><Social Development><Social support><Socioeconomically disadvantaged><Substance Use Disorder><Suicidal thoughts><Suicide><Symptoms><System><Techniques><Tissue Growth><U-Series Cooperative Agreements><United States><Work><Youth><Youth 10-21><adulthood><adverse childhood events><adverse childhood experiences><ages><biological signal transduction><checkup><checkup examination><childrearing><coping><data archive><data archives><data dictionary><data harmonization><data interpretation><dating violence><developmental><deviant peer><disadvantaged background><driving><drug use><early childhood><early experience><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><ethnic subgroup><ethnicity group><evidence base><experience><fatal attempt><fatal suicide><foster care><harmonized data><indexing><intent to die><interest><intervention for prevention><kids><marginalized background><methods to study multiple-level influences><mortality><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><ontogeny><opiate use disorder><opioid use disorder><preparations><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><racial minority group><racial minority individual><racial minority people><racial minority population><racial population><racial subgroup><randomized control trial><randomized, clinical trials><reduce risk><reduce risks><reduce suicidality><reduce suicide><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing suicidality><reducing suicide><reducing the risk><response><risk-reducing><sexual minority adolescent><sexual minority children><sexual minority youth><social><social factors><social support network><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><substance use and disorder><suburb><suburban><suburbia><suicidal behavior><suicidal ideation><suicidal morbidity><suicidal risk><suicidal thinking><suicide behavior><suicide death><suicide ideation><suicide morbidity><suicide risk><suicides><teacher><thoughts about suicide><treatment effect><universal interventions><universal prevention><universal preventive interventions><universal preventive measure><youngster><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rashelle Jean Musci

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,320,210
FY 2025

Project Title

Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodology

Grant Number:

5U01MH137067-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/9/2024

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The goal of this application, submitted in response to RFA-MH-23-275, “Using Secondary Data Analysis to Determine Whether Preventive Interventions Implemented Earlier in Life Reduce Suicide Risk,” is to conduct research that will integrate and harmonize existing large prevention trial datasets. The ...

Research Terms

<0-11 years old><21+ years old><Accidents><Address><Adult><Adult Human><Age><Archives><Area><Automobile Driving><Behavior><Behavioral><Cell Communication and Signaling><Cell Signaling><Cessation of life><Characteristics><Check-up><Child><Child Rearing><Child Youth><Children (0-21)><Collaborations><Communities><Complex><Consent><Cooperative Agreements><Data><Data Analyses><Data Analysis><Data Set><Death><Deposit><Deposition><Detection><Development><Diagnosis><Distal><Documentation><Dose><Drug usage><Early Trauma><Early-life trauma><Effectiveness of Interventions><Elements><Emotional><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Exposure to><Family><Family Nursing><Family-Centered Nursing><Feeling suicidal><Funding><Future><Gender><Gender and Sexual Minorities><Generalized Growth><Geography><Goals><Growth><Heterogeneity><Individual><Intervention><Intervention Strategies><Intracellular Communication and Signaling><Junior High School Student><Junior High Student><Life><Link><Measures><Mediator><Methodology><Middle School Student><Minority><Modeling><NIMH><National Institute of Mental Health><Outcome><Overdose><Parenting><Parenting behavior><Participant><Population><Preparation><Preventative intervention><Preventative strategy><Prevention><Prevention program><Prevention strategy><Prevention trial><Preventive><Preventive strategy><Principal Investigator><Racial Group><Randomized, Controlled Trials><Regulation><Reporting><Research><Research Resources><Resources><Rights><Risk><Risk Reduction><Rural><Schools><Sex Orientation><Sexual Orientation><Sexual and Gender Minorities><Signal Transduction><Signal Transduction Systems><Signaling><Social Development><Social support><Socioeconomically disadvantaged><Substance Use Disorder><Suicidal thoughts><Suicide><Symptoms><System><Techniques><Tissue Growth><U-Series Cooperative Agreements><United States><Work><Youth><Youth 10-21><adulthood><adverse childhood events><adverse childhood experiences><ages><biological signal transduction><checkup><checkup examination><childrearing><coping><data archive><data archives><data dictionary><data harmonization><data interpretation><dating violence><developmental><deviant peer><disadvantaged background><driving><drug use><early childhood><early experience><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><ethnic subgroup><ethnicity group><evidence base><experience><fatal attempt><fatal suicide><foster care><harmonized data><indexing><intent to die><interest><intervention for prevention><kids><marginalized background><methods to study multiple-level influences><mortality><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><ontogeny><opiate use disorder><opioid use disorder><preparations><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><racial minority group><racial minority individual><racial minority people><racial minority population><racial population><racial subgroup><randomized control trial><randomized, clinical trials><reduce risk><reduce risks><reduce suicidality><reduce suicide><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing suicidality><reducing suicide><reducing the risk><response><risk-reducing><sexual minority adolescent><sexual minority children><sexual minority youth><social><social factors><social support network><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><substance use and disorder><suburb><suburban><suburbia><suicidal behavior><suicidal ideation><suicidal morbidity><suicidal risk><suicidal thinking><suicide behavior><suicide death><suicide ideation><suicide morbidity><suicide risk><suicides><teacher><thoughts about suicide><treatment effect><universal interventions><universal prevention><universal preventive interventions><universal preventive measure><youngster><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Holly C Wilcox

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,320,210
FY 2025

Project Title

Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodology

Grant Number:

5U01MH137067-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/9/2024

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The goal of this application, submitted in response to RFA-MH-23-275, “Using Secondary Data Analysis to Determine Whether Preventive Interventions Implemented Earlier in Life Reduce Suicide Risk,” is to conduct research that will integrate and harmonize existing large prevention trial datasets. The ...

Research Terms

<0-11 years old><21+ years old><Accidents><Address><Adult><Adult Human><Age><Archives><Area><Automobile Driving><Behavior><Behavioral><Cell Communication and Signaling><Cell Signaling><Cessation of life><Characteristics><Check-up><Child><Child Rearing><Child Youth><Children (0-21)><Collaborations><Communities><Complex><Consent><Cooperative Agreements><Data><Data Analyses><Data Analysis><Data Set><Death><Deposit><Deposition><Detection><Development><Diagnosis><Distal><Documentation><Dose><Drug usage><Early Trauma><Early-life trauma><Effectiveness of Interventions><Elements><Emotional><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Exposure to><Family><Family Nursing><Family-Centered Nursing><Feeling suicidal><Funding><Future><Gender><Gender and Sexual Minorities><Generalized Growth><Geography><Goals><Growth><Heterogeneity><Individual><Intervention><Intervention Strategies><Intracellular Communication and Signaling><Junior High School Student><Junior High Student><Life><Link><Measures><Mediator><Methodology><Middle School Student><Minority><Modeling><NIMH><National Institute of Mental Health><Outcome><Overdose><Parenting><Parenting behavior><Participant><Population><Preparation><Preventative intervention><Preventative strategy><Prevention><Prevention program><Prevention strategy><Prevention trial><Preventive><Preventive strategy><Principal Investigator><Racial Group><Randomized, Controlled Trials><Regulation><Reporting><Research><Research Resources><Resources><Rights><Risk><Risk Reduction><Rural><Schools><Sex Orientation><Sexual Orientation><Sexual and Gender Minorities><Signal Transduction><Signal Transduction Systems><Signaling><Social Development><Social support><Socioeconomically disadvantaged><Substance Use Disorder><Suicidal thoughts><Suicide><Symptoms><System><Techniques><Tissue Growth><U-Series Cooperative Agreements><United States><Work><Youth><Youth 10-21><adulthood><adverse childhood events><adverse childhood experiences><ages><biological signal transduction><checkup><checkup examination><childrearing><coping><data archive><data archives><data dictionary><data harmonization><data interpretation><dating violence><developmental><deviant peer><disadvantaged background><driving><drug use><early childhood><early experience><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><ethnic subgroup><ethnicity group><evidence base><experience><fatal attempt><fatal suicide><foster care><harmonized data><indexing><intent to die><interest><intervention for prevention><kids><marginalized background><methods to study multiple-level influences><mortality><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><ontogeny><opiate use disorder><opioid use disorder><preparations><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><racial minority group><racial minority individual><racial minority people><racial minority population><racial population><racial subgroup><randomized control trial><randomized, clinical trials><reduce risk><reduce risks><reduce suicidality><reduce suicide><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing suicidality><reducing suicide><reducing the risk><response><risk-reducing><sexual minority adolescent><sexual minority children><sexual minority youth><social><social factors><social support network><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><substance use and disorder><suburb><suburban><suburbia><suicidal behavior><suicidal ideation><suicidal morbidity><suicidal risk><suicidal thinking><suicide behavior><suicide death><suicide ideation><suicide morbidity><suicide risk><suicides><teacher><thoughts about suicide><treatment effect><universal interventions><universal prevention><universal preventive interventions><universal preventive measure><youngster><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KURT R. BRUNDEN

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,250,355
FY 2025

Project Title

Development of a MT-stabilizing agent for the treatment of tauopathies

Grant Number:

5U01AG088051-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2024

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY A group of neurodegenerative diseases referred to as tauopathies, which includes Alzheimer’s disease (AD), are characterized by the presence within brain neurons of inclusions comprised of hyperphosphorylated forms of tau protein. Tau is normally a microtubule (MT)-associated protein...

Research Terms

<AD dementia><Acute><Adverse Experience><Adverse event><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's brain><Alzheimer's disease brain><Alzheimer's disease patient><Alzheimer's patient><Alzheimers Dementia><Axon><Axonal Transport><Axoplasmic Transport><Binding><Binding Proteins><Bioavailability><Biological Availability><Biological Markers><Blood Plasma><Brain><Brain Nervous System><CaCo2><Caco-2 Cells><Canine Species><Canis familiaris><Clinical><Common Rat Strains><Cyclic GMP><Degenerative Neurologic Disorders><Desoxyepothilone B><Development><Disease><Disease Progression><Disorder><Dogs><Dogs Mammals><Dose><Drug Compounding><Drug Kinetics><Drug Preparation><Drugs><Encephalon><Enzyme Gene><Enzymes><Exhibits><FTLD><Formulation><Frontal Temporal Lobar Degeneration><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Future><Gene Alteration><Gene Mutation><Goals><Guanosine Cyclic Monophosphate><Hereditary><IND Filing><IND application><IND package><IND submission><Impairment><In Vitro><Inherited><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Laboratories><Lesion><Ligand Binding Protein><Ligand Binding Protein Gene><Lobar Atrophy of the Brain><MAPT gene><MAPT protein><MT-bound tau><MTBT1><Medication><Metabolic><Mice><Mice Mammals><Micro-tubule><Micronucleus Assays><Micronucleus Tests><Microtubule stabilizing agent><Microtubule-Associated Proteins><Microtubules><Modeling><Modification><Molecular Interaction><Molecular Motors><Murine><Mus><NIH><National Institutes of Health><Natural Products><Nerve Cells><Nerve Degeneration><Nerve Unit><Nervous System Degenerative Diseases><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurofibrillary Tangles><Neurologic Degenerative Conditions><Neuron Degeneration><Neurons><Neuropil Threads><Oral><Pathologic><Patients><Permeability><Pharmaceutical Preparations><Pharmacokinetics><Phase 1b Clinical Trial><Phase 1b Trial><Phase Ib Clinical Trial><Phase Ib Trial><Physiologic Availability><Pick Disease of the Brain><Pick's Disease><Plasma><Plasma Serum><Play><Primary Senile Degenerative Dementia><Process><Progressive Supranuclear Ophthalmoplegia><Progressive Supranuclear Palsy><Protein Binding><Qualifying><Rat><Rats Mammals><Rattus><Reticuloendothelial System, Serum, Plasma><Role><Safety><Science><Solubility><Steele-Richardson-Olszewski Disease><Steele-Richardson-Olszewski Syndrome><Structure><Structure-Activity Relationship><Tauopathies><Testing><Toxic effect><Toxicities><Toxicology><Transgenic Mice><Transgenic Organisms><United States National Institutes of Health><Validation><Work><aqueous><bio-markers><biologic marker><biomarker><bound protein><cGMP><cancer clinical trial><canine><chemical structure function><cognitive performance><cortico-basal syndrome><corticobasal syndrome><dEpoB cpd><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><density><desoxy epothilone B><developmental><domestic dog><drug candidate><drug development><drug/agent><efficacy testing><epothilon D><epothilone D><epothiolone D><gene defect><hyper-phosphorylated tau><hyperphosphorylated tau><improved><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><mouse model><murine model><mutant allele><naturally occurring product><nerve cell death><nerve cell loss><neural degeneration><neurodegeneration><neurodegenerative><neurodegenerative illness><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neurological degeneration><neuron cell death><neuron cell loss><neuron death><neuron loss><neuronal><neuronal cell death><neuronal cell loss><neuronal death><neuronal degeneration><neuronal loss><neuropathologic tau><neuropathological tau><novel><oncology clinical trial><p-tau><p-τ><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><phospho-tau><phospho-τ><phosphorylated tau><post-translational modification of tau><posttranslational modification of tau><pre-clinical><preclinical><primary degenerative dementia><prototype><senile dementia of the Alzheimer type><social role><structure function relationship><tangle><tau><tau Proteins><tau associated neurodegeneration><tau associated neurodegenerative process><tau driven neurodegeneration><tau factor><tau function><tau induced degeneration><tau induced neurodegeneration><tau mediated neurodegeneration><tau neurodegenerative disease><tau neuropathology><tau pathology><tau pathophysiology><tau phosphorylation><tau posttranslational modification><tau proteinopathy><tau related neurodegeneration><tau-1><tau-induced pathology><tauopathic neurodegenerative disorder><tauopathy><transgenic><validations><τ Proteins><τ function><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Conor Caffrey

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,250,355
FY 2025

Project Title

Development of a MT-stabilizing agent for the treatment of tauopathies

Grant Number:

5U01AG088051-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2024

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY A group of neurodegenerative diseases referred to as tauopathies, which includes Alzheimer’s disease (AD), are characterized by the presence within brain neurons of inclusions comprised of hyperphosphorylated forms of tau protein. Tau is normally a microtubule (MT)-associated protein...

Research Terms

<AD dementia><Acute><Adverse Experience><Adverse event><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's brain><Alzheimer's disease brain><Alzheimer's disease patient><Alzheimer's patient><Alzheimers Dementia><Axon><Axonal Transport><Axoplasmic Transport><Binding><Binding Proteins><Bioavailability><Biological Availability><Biological Markers><Blood Plasma><Brain><Brain Nervous System><CaCo2><Caco-2 Cells><Canine Species><Canis familiaris><Clinical><Common Rat Strains><Cyclic GMP><Degenerative Neurologic Disorders><Desoxyepothilone B><Development><Disease><Disease Progression><Disorder><Dogs><Dogs Mammals><Dose><Drug Compounding><Drug Kinetics><Drug Preparation><Drugs><Encephalon><Enzyme Gene><Enzymes><Exhibits><FTLD><Formulation><Frontal Temporal Lobar Degeneration><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Future><Gene Alteration><Gene Mutation><Goals><Guanosine Cyclic Monophosphate><Hereditary><IND Filing><IND application><IND package><IND submission><Impairment><In Vitro><Inherited><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Laboratories><Lesion><Ligand Binding Protein><Ligand Binding Protein Gene><Lobar Atrophy of the Brain><MAPT gene><MAPT protein><MT-bound tau><MTBT1><Medication><Metabolic><Mice><Mice Mammals><Micro-tubule><Micronucleus Assays><Micronucleus Tests><Microtubule stabilizing agent><Microtubule-Associated Proteins><Microtubules><Modeling><Modification><Molecular Interaction><Molecular Motors><Murine><Mus><NIH><National Institutes of Health><Natural Products><Nerve Cells><Nerve Degeneration><Nerve Unit><Nervous System Degenerative Diseases><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurofibrillary Tangles><Neurologic Degenerative Conditions><Neuron Degeneration><Neurons><Neuropil Threads><Oral><Pathologic><Patients><Permeability><Pharmaceutical Preparations><Pharmacokinetics><Phase 1b Clinical Trial><Phase 1b Trial><Phase Ib Clinical Trial><Phase Ib Trial><Physiologic Availability><Pick Disease of the Brain><Pick's Disease><Plasma><Plasma Serum><Play><Primary Senile Degenerative Dementia><Process><Progressive Supranuclear Ophthalmoplegia><Progressive Supranuclear Palsy><Protein Binding><Qualifying><Rat><Rats Mammals><Rattus><Reticuloendothelial System, Serum, Plasma><Role><Safety><Science><Solubility><Steele-Richardson-Olszewski Disease><Steele-Richardson-Olszewski Syndrome><Structure><Structure-Activity Relationship><Tauopathies><Testing><Toxic effect><Toxicities><Toxicology><Transgenic Mice><Transgenic Organisms><United States National Institutes of Health><Validation><Work><aqueous><bio-markers><biologic marker><biomarker><bound protein><cGMP><cancer clinical trial><canine><chemical structure function><cognitive performance><cortico-basal syndrome><corticobasal syndrome><dEpoB cpd><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><density><desoxy epothilone B><developmental><domestic dog><drug candidate><drug development><drug/agent><efficacy testing><epothilon D><epothilone D><epothiolone D><gene defect><hyper-phosphorylated tau><hyperphosphorylated tau><improved><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><mouse model><murine model><mutant allele><naturally occurring product><nerve cell death><nerve cell loss><neural degeneration><neurodegeneration><neurodegenerative><neurodegenerative illness><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neurological degeneration><neuron cell death><neuron cell loss><neuron death><neuron loss><neuronal><neuronal cell death><neuronal cell loss><neuronal death><neuronal degeneration><neuronal loss><neuropathologic tau><neuropathological tau><novel><oncology clinical trial><p-tau><p-τ><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><phospho-tau><phospho-τ><phosphorylated tau><post-translational modification of tau><posttranslational modification of tau><pre-clinical><preclinical><primary degenerative dementia><prototype><senile dementia of the Alzheimer type><social role><structure function relationship><tangle><tau><tau Proteins><tau associated neurodegeneration><tau associated neurodegenerative process><tau driven neurodegeneration><tau factor><tau function><tau induced degeneration><tau induced neurodegeneration><tau mediated neurodegeneration><tau neurodegenerative disease><tau neuropathology><tau pathology><tau pathophysiology><tau phosphorylation><tau posttranslational modification><tau proteinopathy><tau related neurodegeneration><tau-1><tau-induced pathology><tauopathic neurodegenerative disorder><tauopathy><transgenic><validations><τ Proteins><τ function><τ phosphorylation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Oliver Fiehn

DUKE UNIVERSITY, DURHAM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,107,225
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

5U01AG088562-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LEE E. GOLDSTEIN

DUKE UNIVERSITY, DURHAM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,107,225
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

5U01AG088562-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rima F Kaddurah-Daouk

DUKE UNIVERSITY, DURHAM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,107,225
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

5U01AG088562-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Wishart

DUKE UNIVERSITY, DURHAM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,107,225
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

5U01AG088562-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LEE E. GOLDSTEIN

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,018,294
FY 2025

Project Title

Leveraging novel mouse models to investigate toxic metal exposures on brain aging and Alzheimer's disease

Grant Number:

5U01AG088683-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Alzheimer’s disease (AD) and AD-related dementias (ADRDs) are leading causes of cognitive decline and major contributors to morbidity, mortality, and healthcare costs. Cardinal hallmarks of AD brain pathology include amyloid-β (Aβ) plaques, neurofibrillary tangles (hyperphosphorylated tau), neurodeg...

Research Terms

<21+ years old><AD dementia><AD model><AD pathology><AD related dementia><ADRD><APOE e3><APOE e4><APOE-ε4><APOEε4><Acceleration><Address><Adult><Adult Human><Affect><Age><Aging><Airborne Particulate Matter><Alleles><Allelomorphs><Ally><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's amyloid><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease brain><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Amyloid (Aβ) plaques><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid beta-Protein><Amyloid β><Amyloid β-Peptide><Amyloid β-Protein><Aorta><Arsenic><Assay><Astroprotein><Automobile Driving><Autopsy><Autoregulation><Aβ><BBB crossing><Behavior><Bioassay><Biochemical><Bioenergetics><Biological Assay><Biological Markers><Biology><Biometals><Blood><Blood - brain barrier anatomy><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Blood-Brain Barrier><Boston><Brain><Brain Mapping><Brain Nervous System><Brain Pathology><Breeding><Cadmium><Cd element><Chronic><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive deficits><Cognitive function abnormal><Communities><Companions><Contamination in food><Cross Sectional Analysis><Cross-Sectional Analyses><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Dementia><Development><Dextrose><Disease Frequency Surveys><Disparities><Disparity><Disturbance in cognition><Doctor of Philosophy><Dose><Elements><Encephalon><Environmental Exposure><Environmental Factor><Environmental Risk Factor><Environmental Toxin><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Evaluation><Exposure to><Exposure to Pb2+><Female><Food Contamination><GFA-Protein><GFAP><Gene Transcription><Gene x Environment Interaction><Generations><Genes><Genetic><Genetic Diseases><Genetic Transcription><Genetic predisposing factor><Genomics><Geography><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Glucose><Goals><Grant><Groups at risk><GxE interaction><Health><Health Care Costs><Health Costs><Heart><Hemato-Encephalic Barrier><High Fat Diet><Homeostasis><Human><ICP-MS><Image><Impaired cognition><Indiana><Inductively Coupled Plasma Mass Spectrometry><Kidney><Kidney Urinary System><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Late Onset Alzheimer Disease><Lead><Link><Lung><Lung Respiratory System><MT-bound tau><Maps><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Metal exposure><Metals><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Morbidity><Morbidity - disease rate><Murine><Mus><NIEHS><National Institute of Environmental Health Sciences><Nerve Degeneration><Network Analysis><Neural Development><Neuritic Plaques><Neurofibrillary Tangles><Neuron Degeneration><Neurotoxins><North Carolina><Oxidative Stress><PET/CT><PET/CT scan><Pathology><Pathway Analysis><Pb element><Pb exposed><Pb exposure><Pb2+ Exposure><Pb2+ exposed><People at risk><Perfusion><Persons at risk><Ph.D.><PhD><Phenotype><Physiological Homeostasis><Populations at Risk><Position><Positioning Attribute><Pre-Clinical Model><Preclinical Models><Primary Senile Degenerative Dementia><Process><Protocol><Protocols documentation><RNA Expression><Race><Races><Research><Research Design><Research Resources><Resolution><Resources><Risk><Risk Factors><Role><Route><Sedentary behavior><Sedentary life-style><Senile Plaques><Structure><Study Type><The Jackson Laboratory><Tissue Banks><Tissue Collection><Tissue repository><Toxic Environmental Agents><Toxic Environmental Substances><Toxicant exposure><Trace Elements><Trace Mineral><Transcription><Universities><Variant><Variation><Vascular Diseases><Vascular Disorder><a beta peptide><abeta><adulthood><age associated><age correlated><age dependent><age linked><age related><age specific><aged><aged brain><ages><aging brain><airborne particulate><alzheimer model><alzheimer risk><amyloid beta><amyloid beta plaque><amyloid-b plaque><amyloid-b protein><apo E-3><apo E-4><apo E3><apo E4><apo epsilon4><apoE epsilon 4><apoE-3><apoE-4><apoE3><apoE4><apolipoprotein E epsilon 4><apolipoprotein E-3><apolipoprotein E-4><apolipoprotein E3><apolipoprotein E4><arsenics><aβ plaques><beta amyloid fibril><bio-markers><biobank><biologic marker><biomarker><biorepository><blood vessel disorder><blood-based biomarker><blood-based marker><blood-brain barrier crossing><bloodbrain barrier><bloodbrain barrier crossing><bone><brain health><clinical relevance><clinically relevant><cognitive defects><cognitive dysfunction><cognitive loss><community level disadvantage><cored plaque><data resource><dementia risk><demographics><developmental><diffuse plaque><disadvantaged community><disease phenotype><drinking water><driving><environment effect on gene><environmental risk><environmental toxicant><epigenetically><epigenome profiling><epigenomic profiling><epigenomics><experience><exposed to lead><exposome><exposure to Pb><exposure to lead><exposure to metal><gene environment interaction><genetic condition><genetic disorder><genetic risk factor><heavy metal Pb><heavy metal lead><human data><hyper-phosphorylated tau><hyperphosphorylated tau><imaging><imaging in vivo><in vivo imaging><inherited factor><innovate><innovation><innovative><late onset alzheimer><lead exposed><lead exposure><life span><lifespan><male><metabolism measurement><metabolomics><metabonomics><microtubule bound tau><microtubule-bound tau><model organism><mortality><mouse model><multidisciplinary><multiomics><multiple omics><murine model><necropsy><neighborhood barrier><neighborhood disadvantage><neighborhood-level barrier><neighborhood-level disadvantage><neural degeneration><neural imaging><neural inflammation><neuro-imaging><neurodegeneration><neurodegenerative><neurodevelopment><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neuroimaging><neuroinflammation><neuroinflammatory><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><neurotoxic><neurotoxicant><novel><panomics><positron emission computed tomography><postmortem><pre-clinical><pre-clinical study><preclinical><preclinical study><prenatal><primary degenerative dementia><protein expression><racial><racial background><racial origin><renal><resolutions><response><risk factor for dementia><risk for dementia><sedentary lifestyle><senile dementia of the Alzheimer type><sex><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><soluble amyloid precursor protein><study design><synergism><tangle><tau><tau Proteins><tau factor><toxic exposure><toxic metal><toxicant><unborn><vascular dysfunction><vasculopathy><τ Proteins><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gareth R Howell

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,018,294
FY 2025

Project Title

Leveraging novel mouse models to investigate toxic metal exposures on brain aging and Alzheimer's disease

Grant Number:

5U01AG088683-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Alzheimer’s disease (AD) and AD-related dementias (ADRDs) are leading causes of cognitive decline and major contributors to morbidity, mortality, and healthcare costs. Cardinal hallmarks of AD brain pathology include amyloid-β (Aβ) plaques, neurofibrillary tangles (hyperphosphorylated tau), neurodeg...

Research Terms

<21+ years old><AD dementia><AD model><AD pathology><AD related dementia><ADRD><APOE e3><APOE e4><APOE-ε4><APOEε4><Acceleration><Address><Adult><Adult Human><Affect><Age><Aging><Airborne Particulate Matter><Alleles><Allelomorphs><Ally><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's amyloid><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease brain><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Amyloid (Aβ) plaques><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid beta-Protein><Amyloid β><Amyloid β-Peptide><Amyloid β-Protein><Aorta><Arsenic><Assay><Astroprotein><Automobile Driving><Autopsy><Autoregulation><Aβ><BBB crossing><Behavior><Bioassay><Biochemical><Bioenergetics><Biological Assay><Biological Markers><Biology><Biometals><Blood><Blood - brain barrier anatomy><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Blood-Brain Barrier><Boston><Brain><Brain Mapping><Brain Nervous System><Brain Pathology><Breeding><Cadmium><Cd element><Chronic><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive deficits><Cognitive function abnormal><Communities><Companions><Contamination in food><Cross Sectional Analysis><Cross-Sectional Analyses><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Dementia><Development><Dextrose><Disease Frequency Surveys><Disparities><Disparity><Disturbance in cognition><Doctor of Philosophy><Dose><Elements><Encephalon><Environmental Exposure><Environmental Factor><Environmental Risk Factor><Environmental Toxin><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Evaluation><Exposure to><Exposure to Pb2+><Female><Food Contamination><GFA-Protein><GFAP><Gene Transcription><Gene x Environment Interaction><Generations><Genes><Genetic><Genetic Diseases><Genetic Transcription><Genetic predisposing factor><Genomics><Geography><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Glucose><Goals><Grant><Groups at risk><GxE interaction><Health><Health Care Costs><Health Costs><Heart><Hemato-Encephalic Barrier><High Fat Diet><Homeostasis><Human><ICP-MS><Image><Impaired cognition><Indiana><Inductively Coupled Plasma Mass Spectrometry><Kidney><Kidney Urinary System><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Late Onset Alzheimer Disease><Lead><Link><Lung><Lung Respiratory System><MT-bound tau><Maps><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Metal exposure><Metals><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Morbidity><Morbidity - disease rate><Murine><Mus><NIEHS><National Institute of Environmental Health Sciences><Nerve Degeneration><Network Analysis><Neural Development><Neuritic Plaques><Neurofibrillary Tangles><Neuron Degeneration><Neurotoxins><North Carolina><Oxidative Stress><PET/CT><PET/CT scan><Pathology><Pathway Analysis><Pb element><Pb exposed><Pb exposure><Pb2+ Exposure><Pb2+ exposed><People at risk><Perfusion><Persons at risk><Ph.D.><PhD><Phenotype><Physiological Homeostasis><Populations at Risk><Position><Positioning Attribute><Pre-Clinical Model><Preclinical Models><Primary Senile Degenerative Dementia><Process><Protocol><Protocols documentation><RNA Expression><Race><Races><Research><Research Design><Research Resources><Resolution><Resources><Risk><Risk Factors><Role><Route><Sedentary behavior><Sedentary life-style><Senile Plaques><Structure><Study Type><The Jackson Laboratory><Tissue Banks><Tissue Collection><Tissue repository><Toxic Environmental Agents><Toxic Environmental Substances><Toxicant exposure><Trace Elements><Trace Mineral><Transcription><Universities><Variant><Variation><Vascular Diseases><Vascular Disorder><a beta peptide><abeta><adulthood><age associated><age correlated><age dependent><age linked><age related><age specific><aged><aged brain><ages><aging brain><airborne particulate><alzheimer model><alzheimer risk><amyloid beta><amyloid beta plaque><amyloid-b plaque><amyloid-b protein><apo E-3><apo E-4><apo E3><apo E4><apo epsilon4><apoE epsilon 4><apoE-3><apoE-4><apoE3><apoE4><apolipoprotein E epsilon 4><apolipoprotein E-3><apolipoprotein E-4><apolipoprotein E3><apolipoprotein E4><arsenics><aβ plaques><beta amyloid fibril><bio-markers><biobank><biologic marker><biomarker><biorepository><blood vessel disorder><blood-based biomarker><blood-based marker><blood-brain barrier crossing><bloodbrain barrier><bloodbrain barrier crossing><bone><brain health><clinical relevance><clinically relevant><cognitive defects><cognitive dysfunction><cognitive loss><community level disadvantage><cored plaque><data resource><dementia risk><demographics><developmental><diffuse plaque><disadvantaged community><disease phenotype><drinking water><driving><environment effect on gene><environmental risk><environmental toxicant><epigenetically><epigenome profiling><epigenomic profiling><epigenomics><experience><exposed to lead><exposome><exposure to Pb><exposure to lead><exposure to metal><gene environment interaction><genetic condition><genetic disorder><genetic risk factor><heavy metal Pb><heavy metal lead><human data><hyper-phosphorylated tau><hyperphosphorylated tau><imaging><imaging in vivo><in vivo imaging><inherited factor><innovate><innovation><innovative><late onset alzheimer><lead exposed><lead exposure><life span><lifespan><male><metabolism measurement><metabolomics><metabonomics><microtubule bound tau><microtubule-bound tau><model organism><mortality><mouse model><multidisciplinary><multiomics><multiple omics><murine model><necropsy><neighborhood barrier><neighborhood disadvantage><neighborhood-level barrier><neighborhood-level disadvantage><neural degeneration><neural imaging><neural inflammation><neuro-imaging><neurodegeneration><neurodegenerative><neurodevelopment><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neuroimaging><neuroinflammation><neuroinflammatory><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><neurotoxic><neurotoxicant><novel><panomics><positron emission computed tomography><postmortem><pre-clinical><pre-clinical study><preclinical><preclinical study><prenatal><primary degenerative dementia><protein expression><racial><racial background><racial origin><renal><resolutions><response><risk factor for dementia><risk for dementia><sedentary lifestyle><senile dementia of the Alzheimer type><sex><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><soluble amyloid precursor protein><study design><synergism><tangle><tau><tau Proteins><tau factor><toxic exposure><toxic metal><toxicant><unborn><vascular dysfunction><vasculopathy><τ Proteins><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Paul Richard Territo

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,018,294
FY 2025

Project Title

Leveraging novel mouse models to investigate toxic metal exposures on brain aging and Alzheimer's disease

Grant Number:

5U01AG088683-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Alzheimer’s disease (AD) and AD-related dementias (ADRDs) are leading causes of cognitive decline and major contributors to morbidity, mortality, and healthcare costs. Cardinal hallmarks of AD brain pathology include amyloid-β (Aβ) plaques, neurofibrillary tangles (hyperphosphorylated tau), neurodeg...

Research Terms

<21+ years old><AD dementia><AD model><AD pathology><AD related dementia><ADRD><APOE e3><APOE e4><APOE-ε4><APOEε4><Acceleration><Address><Adult><Adult Human><Affect><Age><Aging><Airborne Particulate Matter><Alleles><Allelomorphs><Ally><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's amyloid><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease brain><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Amyloid (Aβ) plaques><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid beta-Protein><Amyloid β><Amyloid β-Peptide><Amyloid β-Protein><Aorta><Arsenic><Assay><Astroprotein><Automobile Driving><Autopsy><Autoregulation><Aβ><BBB crossing><Behavior><Bioassay><Biochemical><Bioenergetics><Biological Assay><Biological Markers><Biology><Biometals><Blood><Blood - brain barrier anatomy><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Blood-Brain Barrier><Boston><Brain><Brain Mapping><Brain Nervous System><Brain Pathology><Breeding><Cadmium><Cd element><Chronic><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive deficits><Cognitive function abnormal><Communities><Companions><Contamination in food><Cross Sectional Analysis><Cross-Sectional Analyses><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Dementia><Development><Dextrose><Disease Frequency Surveys><Disparities><Disparity><Disturbance in cognition><Doctor of Philosophy><Dose><Elements><Encephalon><Environmental Exposure><Environmental Factor><Environmental Risk Factor><Environmental Toxin><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Evaluation><Exposure to><Exposure to Pb2+><Female><Food Contamination><GFA-Protein><GFAP><Gene Transcription><Gene x Environment Interaction><Generations><Genes><Genetic><Genetic Diseases><Genetic Transcription><Genetic predisposing factor><Genomics><Geography><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Glucose><Goals><Grant><Groups at risk><GxE interaction><Health><Health Care Costs><Health Costs><Heart><Hemato-Encephalic Barrier><High Fat Diet><Homeostasis><Human><ICP-MS><Image><Impaired cognition><Indiana><Inductively Coupled Plasma Mass Spectrometry><Kidney><Kidney Urinary System><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Late Onset Alzheimer Disease><Lead><Link><Lung><Lung Respiratory System><MT-bound tau><Maps><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Metal exposure><Metals><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Morbidity><Morbidity - disease rate><Murine><Mus><NIEHS><National Institute of Environmental Health Sciences><Nerve Degeneration><Network Analysis><Neural Development><Neuritic Plaques><Neurofibrillary Tangles><Neuron Degeneration><Neurotoxins><North Carolina><Oxidative Stress><PET/CT><PET/CT scan><Pathology><Pathway Analysis><Pb element><Pb exposed><Pb exposure><Pb2+ Exposure><Pb2+ exposed><People at risk><Perfusion><Persons at risk><Ph.D.><PhD><Phenotype><Physiological Homeostasis><Populations at Risk><Position><Positioning Attribute><Pre-Clinical Model><Preclinical Models><Primary Senile Degenerative Dementia><Process><Protocol><Protocols documentation><RNA Expression><Race><Races><Research><Research Design><Research Resources><Resolution><Resources><Risk><Risk Factors><Role><Route><Sedentary behavior><Sedentary life-style><Senile Plaques><Structure><Study Type><The Jackson Laboratory><Tissue Banks><Tissue Collection><Tissue repository><Toxic Environmental Agents><Toxic Environmental Substances><Toxicant exposure><Trace Elements><Trace Mineral><Transcription><Universities><Variant><Variation><Vascular Diseases><Vascular Disorder><a beta peptide><abeta><adulthood><age associated><age correlated><age dependent><age linked><age related><age specific><aged><aged brain><ages><aging brain><airborne particulate><alzheimer model><alzheimer risk><amyloid beta><amyloid beta plaque><amyloid-b plaque><amyloid-b protein><apo E-3><apo E-4><apo E3><apo E4><apo epsilon4><apoE epsilon 4><apoE-3><apoE-4><apoE3><apoE4><apolipoprotein E epsilon 4><apolipoprotein E-3><apolipoprotein E-4><apolipoprotein E3><apolipoprotein E4><arsenics><aβ plaques><beta amyloid fibril><bio-markers><biobank><biologic marker><biomarker><biorepository><blood vessel disorder><blood-based biomarker><blood-based marker><blood-brain barrier crossing><bloodbrain barrier><bloodbrain barrier crossing><bone><brain health><clinical relevance><clinically relevant><cognitive defects><cognitive dysfunction><cognitive loss><community level disadvantage><cored plaque><data resource><dementia risk><demographics><developmental><diffuse plaque><disadvantaged community><disease phenotype><drinking water><driving><environment effect on gene><environmental risk><environmental toxicant><epigenetically><epigenome profiling><epigenomic profiling><epigenomics><experience><exposed to lead><exposome><exposure to Pb><exposure to lead><exposure to metal><gene environment interaction><genetic condition><genetic disorder><genetic risk factor><heavy metal Pb><heavy metal lead><human data><hyper-phosphorylated tau><hyperphosphorylated tau><imaging><imaging in vivo><in vivo imaging><inherited factor><innovate><innovation><innovative><late onset alzheimer><lead exposed><lead exposure><life span><lifespan><male><metabolism measurement><metabolomics><metabonomics><microtubule bound tau><microtubule-bound tau><model organism><mortality><mouse model><multidisciplinary><multiomics><multiple omics><murine model><necropsy><neighborhood barrier><neighborhood disadvantage><neighborhood-level barrier><neighborhood-level disadvantage><neural degeneration><neural imaging><neural inflammation><neuro-imaging><neurodegeneration><neurodegenerative><neurodevelopment><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neuroimaging><neuroinflammation><neuroinflammatory><neurological degeneration><neurological imaging><neuronal degeneration><neuropathologic><neuropathological><neuropathology><neurotoxic><neurotoxicant><novel><panomics><positron emission computed tomography><postmortem><pre-clinical><pre-clinical study><preclinical><preclinical study><prenatal><primary degenerative dementia><protein expression><racial><racial background><racial origin><renal><resolutions><response><risk factor for dementia><risk for dementia><sedentary lifestyle><senile dementia of the Alzheimer type><sex><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><soluble amyloid precursor protein><study design><synergism><tangle><tau><tau Proteins><tau factor><toxic exposure><toxic metal><toxicant><unborn><vascular dysfunction><vasculopathy><τ Proteins><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

FRANCINE GRODSTEIN

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,940,803
FY 2025

Project Title

Mexican Teachers Cohort Study: Genetics and Cognitive Function

Grant Number:

5U01AG084547-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

This is a resubmission of a U01 application for the “Alzheimer’s Disease Sequencing Project (ADSP) Follow- Up Study 2.0: The Diverse Population Initiative” (PAR-21-212). The overall goals are to: (i) contribute nearly 20,000 GWAS and 5000 whole genome sequences to ADSP from participants of the “Estu...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD dementia><AD related dementia><ADRD><Active Follow-up><Address><Admixture><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Amerindian><Autopsy><Blood Sample><Blood specimen><Central American><Chicanas><Chicanos><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Collaborations><Complement><Complement Proteins><Concurrent Studies><DNA><Data><Dementia><Deoxyribonucleic Acid><Diagnosis><Disturbance in cognition><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Follow-Up Studies><Followup Studies><GWA study><GWAS><Genes><Genetic><Genetic Determinism><Genetic Diversity><Genetic Variation><Genome><Genomics><Genotype><Goals><Health><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Impaired cognition><Indigenous><Individual><Investigators><Length><Linkage Disequilibrium><Maps><Measures><Mexican><Mexican Americans><Mexico><Mitochondrial DNA><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Other Genetics><Participant><Pathologic><Pathway interactions><Pattern><Phenotype><Population><Population Heterogeneity><Primary Senile Degenerative Dementia><Process><Research><Research Personnel><Research Specimen><Research Support><Researchers><Resource Sharing><Sampling><Secondary to><South American><Specimen><Testing><Time><Universities><Variant><Variation><Woman><Women's cohort><above age 65><active followup><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><ancestry analysis><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><cognitive assessment><cognitive dysfunction><cognitive function><cognitive loss><cognitive testing><cohort><cohort in women><cohort on women><complementation><data harmonization><data hub><depository><design><designing><diverse populations><entire genome><ethnic subgroup><ethnicity group><experience><female cohort><follow up><follow-up><followed up><followup><full genome><genetic determinant><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><harmonized data><heterogeneous population><heteroplasmy><human old age (65+)><improved><men><mtDNA><necropsy><neuropathologic><neuropathological><neuropathology><novel><over 65 years><pathway><population diversity><postmortem><primary degenerative dementia><recruit><repository><screening><screenings><senile dementia of the Alzheimer type><sharing hub><social health determinants><teacher><telomere><trait><whole genome><whole genome association analysis><whole genome association study><younger age><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Martin Lajous

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,940,803
FY 2025

Project Title

Mexican Teachers Cohort Study: Genetics and Cognitive Function

Grant Number:

5U01AG084547-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

This is a resubmission of a U01 application for the “Alzheimer’s Disease Sequencing Project (ADSP) Follow- Up Study 2.0: The Diverse Population Initiative” (PAR-21-212). The overall goals are to: (i) contribute nearly 20,000 GWAS and 5000 whole genome sequences to ADSP from participants of the “Estu...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD dementia><AD related dementia><ADRD><Active Follow-up><Address><Admixture><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Amerindian><Autopsy><Blood Sample><Blood specimen><Central American><Chicanas><Chicanos><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Collaborations><Complement><Complement Proteins><Concurrent Studies><DNA><Data><Dementia><Deoxyribonucleic Acid><Diagnosis><Disturbance in cognition><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Follow-Up Studies><Followup Studies><GWA study><GWAS><Genes><Genetic><Genetic Determinism><Genetic Diversity><Genetic Variation><Genome><Genomics><Genotype><Goals><Health><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Impaired cognition><Indigenous><Individual><Investigators><Length><Linkage Disequilibrium><Maps><Measures><Mexican><Mexican Americans><Mexico><Mitochondrial DNA><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Other Genetics><Participant><Pathologic><Pathway interactions><Pattern><Phenotype><Population><Population Heterogeneity><Primary Senile Degenerative Dementia><Process><Research><Research Personnel><Research Specimen><Research Support><Researchers><Resource Sharing><Sampling><Secondary to><South American><Specimen><Testing><Time><Universities><Variant><Variation><Woman><Women's cohort><above age 65><active followup><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><ancestry analysis><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><cognitive assessment><cognitive dysfunction><cognitive function><cognitive loss><cognitive testing><cohort><cohort in women><cohort on women><complementation><data harmonization><data hub><depository><design><designing><diverse populations><entire genome><ethnic subgroup><ethnicity group><experience><female cohort><follow up><follow-up><followed up><followup><full genome><genetic determinant><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><harmonized data><heterogeneous population><heteroplasmy><human old age (65+)><improved><men><mtDNA><necropsy><neuropathologic><neuropathological><neuropathology><novel><over 65 years><pathway><population diversity><postmortem><primary degenerative dementia><recruit><repository><screening><screenings><senile dementia of the Alzheimer type><sharing hub><social health determinants><teacher><telomere><trait><whole genome><whole genome association analysis><whole genome association study><younger age><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

A. Dimitrios Colevas

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,903,401
FY 2025

Project Title

Phase 1 and 2 Molecular and Clinical Pharmacodynamic Trials ETCTN

Grant Number:

5UM1CA186717-09

Activity Code:

UM1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/28/2014

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY As the California Cancer Consortium (CCC), four National Cancer Institute (NCI)-Designated Cancer Centers propose to participate in the NCI Experimental Therapeutics Clinical Trials Network (ETCTN) to conduct early phase clinical trials of experimental therapeutics. The CCC compris...

Research Terms

<Acceleration><Adherence><After Care><After-Treatment><Aftercare><Bioinformatics><Biological Markers><Biopsy><Biostatistics Core><CTEP><California><Cancer Center><Cancer Therapy Evaluation Program><Cancer Treatment><Cancers><Cell Communication and Signaling><Cell Cycle Control><Cell Cycle Regulation><Cell Signaling><Cities><Clinic><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Network><Clinical Trials Support Unit><Collaborations><Combined Modality Therapy><Communication><Comprehensive Cancer Center><Contracting Opportunities><Contracts><Cooperative Agreements><Credentialing><DNA Damage Repair><DNA Repair><Data><Data Coordinating Center><Data Coordination Center><Development><Disease><Disorder><Dose><Drug Kinetics><Drugs><ET-CTN><Early Therapeutic-Clinical Trials Network><Eligibility><Eligibility Determination><Ensure><Environment><Experimental Therapies><Fellowship><Funding><Goals><History><Image><Immunooncology><Individual><Individuals from minority><Individuals of minority><Infrastructure><Institution><Internet><Interventional radiology><Intracellular Communication and Signaling><Investigational Drugs><Investigational New Drugs><Investigational Therapies><Investigational Treatments><Investigators><Joints><Laboratories><Lead><Leadership><Letters><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Medication><Mentors><Mentorship><Methodology><Minority Groups><Minority People><Minority Population><Minority individual><Molecular><Molecular Target><Monitor><Multimodal Therapy><Multimodal Treatment><NCI Organization><National Cancer Institute><Normal Tissue><Normal tissue morphology><Organizational Affiliation><Outcome><Pathology><Patient Selection><Patients><Pb element><Pharmaceutical Preparations><Pharmacodynamics><Pharmacogenomics><Pharmacokinetics><Pharmacology><Phase><Phase 4 Clinical Trials><Phase IV Clinical Trials><Policies><Preclinical data><Prediction of Response to Therapy><Principal Investigator><Procedures><Productivity><Protocol><Protocol Screening><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Research Personnel><Research Resources><Researchers><Resources><Safety><Science><Signal Transduction><Signal Transduction Pathway><Signal Transduction Systems><Signaling><Site><Specialty><Therapeutic><Time><Toxic effect><Toxicities><Translational Research><Translational Science><Tumor Cell><U-Series Cooperative Agreements><Universities><Unscheduled DNA Synthesis><Validation><Veins><WWW><anti-cancer therapy><bio-markers><biologic marker><biological signal transduction><biomarker><cancer immunology><cancer microenvironment><cancer therapy><cancer-directed therapy><cancers that are rare><career><career development><combination therapy><combined modality treatment><combined treatment><conference><convention><design><designing><developmental><drug/agent><early clinical trial><early phase clinical trial><early phase trial><experimental therapeutic agents><experimental therapeutics><heavy metal Pb><heavy metal lead><histories><imaging><immune-oncology><immuno oncology><immunology oncology><improved><innovate><innovation><innovative><insight><malignancy><medical specialties><meeting><meetings><member><minority patient><multi-modal therapy><multi-modal treatment><multidisciplinary><neoplasm immunology><neoplasm/cancer><neoplastic cell><new anti-cancer agent><new anticancer agent><new anticancer drug><new antineoplastic><new cancer drug><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><non-invasive imaging><noninvasive imaging><novel><novel anti-cancer agent><novel anti-cancer drug><novel anticancer agent><novel anticancer drug><novel antineoplastic><novel cancer drug><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><oncoimmunology><patients from minority><patients of minority><post treatment><pre-clinical><preclinical><preclinical findings><preclinical information><predict therapeutic response><predict therapy response><programs><rare cancer><rare malignancy><rare tumor><summit><symposia><symposium><therapy prediction><timeline><translation research><translational investigation><translational investigator><translational researcher><translational scientist><treatment prediction><treatment response prediction><tumor><tumor immunology><tumor microenvironment><validations><web><world wide web>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alexey V. Danilov

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,903,401
FY 2025

Project Title

Phase 1 and 2 Molecular and Clinical Pharmacodynamic Trials ETCTN

Grant Number:

5UM1CA186717-09

Activity Code:

UM1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/28/2014

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY As the California Cancer Consortium (CCC), four National Cancer Institute (NCI)-Designated Cancer Centers propose to participate in the NCI Experimental Therapeutics Clinical Trials Network (ETCTN) to conduct early phase clinical trials of experimental therapeutics. The CCC compris...

Research Terms

<Acceleration><Adherence><After Care><After-Treatment><Aftercare><Bioinformatics><Biological Markers><Biopsy><Biostatistics Core><CTEP><California><Cancer Center><Cancer Therapy Evaluation Program><Cancer Treatment><Cancers><Cell Communication and Signaling><Cell Cycle Control><Cell Cycle Regulation><Cell Signaling><Cities><Clinic><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Network><Clinical Trials Support Unit><Collaborations><Combined Modality Therapy><Communication><Comprehensive Cancer Center><Contracting Opportunities><Contracts><Cooperative Agreements><Credentialing><DNA Damage Repair><DNA Repair><Data><Data Coordinating Center><Data Coordination Center><Development><Disease><Disorder><Dose><Drug Kinetics><Drugs><ET-CTN><Early Therapeutic-Clinical Trials Network><Eligibility><Eligibility Determination><Ensure><Environment><Experimental Therapies><Fellowship><Funding><Goals><History><Image><Immunooncology><Individual><Individuals from minority><Individuals of minority><Infrastructure><Institution><Internet><Interventional radiology><Intracellular Communication and Signaling><Investigational Drugs><Investigational New Drugs><Investigational Therapies><Investigational Treatments><Investigators><Joints><Laboratories><Lead><Leadership><Letters><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Medication><Mentors><Mentorship><Methodology><Minority Groups><Minority People><Minority Population><Minority individual><Molecular><Molecular Target><Monitor><Multimodal Therapy><Multimodal Treatment><NCI Organization><National Cancer Institute><Normal Tissue><Normal tissue morphology><Organizational Affiliation><Outcome><Pathology><Patient Selection><Patients><Pb element><Pharmaceutical Preparations><Pharmacodynamics><Pharmacogenomics><Pharmacokinetics><Pharmacology><Phase><Phase 4 Clinical Trials><Phase IV Clinical Trials><Policies><Preclinical data><Prediction of Response to Therapy><Principal Investigator><Procedures><Productivity><Protocol><Protocol Screening><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Research Personnel><Research Resources><Researchers><Resources><Safety><Science><Signal Transduction><Signal Transduction Pathway><Signal Transduction Systems><Signaling><Site><Specialty><Therapeutic><Time><Toxic effect><Toxicities><Translational Research><Translational Science><Tumor Cell><U-Series Cooperative Agreements><Universities><Unscheduled DNA Synthesis><Validation><Veins><WWW><anti-cancer therapy><bio-markers><biologic marker><biological signal transduction><biomarker><cancer immunology><cancer microenvironment><cancer therapy><cancer-directed therapy><cancers that are rare><career><career development><combination therapy><combined modality treatment><combined treatment><conference><convention><design><designing><developmental><drug/agent><early clinical trial><early phase clinical trial><early phase trial><experimental therapeutic agents><experimental therapeutics><heavy metal Pb><heavy metal lead><histories><imaging><immune-oncology><immuno oncology><immunology oncology><improved><innovate><innovation><innovative><insight><malignancy><medical specialties><meeting><meetings><member><minority patient><multi-modal therapy><multi-modal treatment><multidisciplinary><neoplasm immunology><neoplasm/cancer><neoplastic cell><new anti-cancer agent><new anticancer agent><new anticancer drug><new antineoplastic><new cancer drug><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><non-invasive imaging><noninvasive imaging><novel><novel anti-cancer agent><novel anti-cancer drug><novel anticancer agent><novel anticancer drug><novel antineoplastic><novel cancer drug><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><oncoimmunology><patients from minority><patients of minority><post treatment><pre-clinical><preclinical><preclinical findings><preclinical information><predict therapeutic response><predict therapy response><programs><rare cancer><rare malignancy><rare tumor><summit><symposia><symposium><therapy prediction><timeline><translation research><translational investigation><translational investigator><translational researcher><translational scientist><treatment prediction><treatment response prediction><tumor><tumor immunology><tumor microenvironment><validations><web><world wide web>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PRIMO N. LARA

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,903,401
FY 2025

Project Title

Phase 1 and 2 Molecular and Clinical Pharmacodynamic Trials ETCTN

Grant Number:

5UM1CA186717-09

Activity Code:

UM1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/28/2014

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY As the California Cancer Consortium (CCC), four National Cancer Institute (NCI)-Designated Cancer Centers propose to participate in the NCI Experimental Therapeutics Clinical Trials Network (ETCTN) to conduct early phase clinical trials of experimental therapeutics. The CCC compris...

Research Terms

<Acceleration><Adherence><After Care><After-Treatment><Aftercare><Bioinformatics><Biological Markers><Biopsy><Biostatistics Core><CTEP><California><Cancer Center><Cancer Therapy Evaluation Program><Cancer Treatment><Cancers><Cell Communication and Signaling><Cell Cycle Control><Cell Cycle Regulation><Cell Signaling><Cities><Clinic><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Network><Clinical Trials Support Unit><Collaborations><Combined Modality Therapy><Communication><Comprehensive Cancer Center><Contracting Opportunities><Contracts><Cooperative Agreements><Credentialing><DNA Damage Repair><DNA Repair><Data><Data Coordinating Center><Data Coordination Center><Development><Disease><Disorder><Dose><Drug Kinetics><Drugs><ET-CTN><Early Therapeutic-Clinical Trials Network><Eligibility><Eligibility Determination><Ensure><Environment><Experimental Therapies><Fellowship><Funding><Goals><History><Image><Immunooncology><Individual><Individuals from minority><Individuals of minority><Infrastructure><Institution><Internet><Interventional radiology><Intracellular Communication and Signaling><Investigational Drugs><Investigational New Drugs><Investigational Therapies><Investigational Treatments><Investigators><Joints><Laboratories><Lead><Leadership><Letters><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Medication><Mentors><Mentorship><Methodology><Minority Groups><Minority People><Minority Population><Minority individual><Molecular><Molecular Target><Monitor><Multimodal Therapy><Multimodal Treatment><NCI Organization><National Cancer Institute><Normal Tissue><Normal tissue morphology><Organizational Affiliation><Outcome><Pathology><Patient Selection><Patients><Pb element><Pharmaceutical Preparations><Pharmacodynamics><Pharmacogenomics><Pharmacokinetics><Pharmacology><Phase><Phase 4 Clinical Trials><Phase IV Clinical Trials><Policies><Preclinical data><Prediction of Response to Therapy><Principal Investigator><Procedures><Productivity><Protocol><Protocol Screening><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Research Personnel><Research Resources><Researchers><Resources><Safety><Science><Signal Transduction><Signal Transduction Pathway><Signal Transduction Systems><Signaling><Site><Specialty><Therapeutic><Time><Toxic effect><Toxicities><Translational Research><Translational Science><Tumor Cell><U-Series Cooperative Agreements><Universities><Unscheduled DNA Synthesis><Validation><Veins><WWW><anti-cancer therapy><bio-markers><biologic marker><biological signal transduction><biomarker><cancer immunology><cancer microenvironment><cancer therapy><cancer-directed therapy><cancers that are rare><career><career development><combination therapy><combined modality treatment><combined treatment><conference><convention><design><designing><developmental><drug/agent><early clinical trial><early phase clinical trial><early phase trial><experimental therapeutic agents><experimental therapeutics><heavy metal Pb><heavy metal lead><histories><imaging><immune-oncology><immuno oncology><immunology oncology><improved><innovate><innovation><innovative><insight><malignancy><medical specialties><meeting><meetings><member><minority patient><multi-modal therapy><multi-modal treatment><multidisciplinary><neoplasm immunology><neoplasm/cancer><neoplastic cell><new anti-cancer agent><new anticancer agent><new anticancer drug><new antineoplastic><new cancer drug><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><non-invasive imaging><noninvasive imaging><novel><novel anti-cancer agent><novel anti-cancer drug><novel anticancer agent><novel anticancer drug><novel antineoplastic><novel cancer drug><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><oncoimmunology><patients from minority><patients of minority><post treatment><pre-clinical><preclinical><preclinical findings><preclinical information><predict therapeutic response><predict therapy response><programs><rare cancer><rare malignancy><rare tumor><summit><symposia><symposium><therapy prediction><timeline><translation research><translational investigation><translational investigator><translational researcher><translational scientist><treatment prediction><treatment response prediction><tumor><tumor immunology><tumor microenvironment><validations><web><world wide web>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HEINZ JOSEF LENZ

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,903,401
FY 2025

Project Title

Phase 1 and 2 Molecular and Clinical Pharmacodynamic Trials ETCTN

Grant Number:

5UM1CA186717-09

Activity Code:

UM1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/28/2014

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY As the California Cancer Consortium (CCC), four National Cancer Institute (NCI)-Designated Cancer Centers propose to participate in the NCI Experimental Therapeutics Clinical Trials Network (ETCTN) to conduct early phase clinical trials of experimental therapeutics. The CCC compris...

Research Terms

<Acceleration><Adherence><After Care><After-Treatment><Aftercare><Bioinformatics><Biological Markers><Biopsy><Biostatistics Core><CTEP><California><Cancer Center><Cancer Therapy Evaluation Program><Cancer Treatment><Cancers><Cell Communication and Signaling><Cell Cycle Control><Cell Cycle Regulation><Cell Signaling><Cities><Clinic><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Network><Clinical Trials Support Unit><Collaborations><Combined Modality Therapy><Communication><Comprehensive Cancer Center><Contracting Opportunities><Contracts><Cooperative Agreements><Credentialing><DNA Damage Repair><DNA Repair><Data><Data Coordinating Center><Data Coordination Center><Development><Disease><Disorder><Dose><Drug Kinetics><Drugs><ET-CTN><Early Therapeutic-Clinical Trials Network><Eligibility><Eligibility Determination><Ensure><Environment><Experimental Therapies><Fellowship><Funding><Goals><History><Image><Immunooncology><Individual><Individuals from minority><Individuals of minority><Infrastructure><Institution><Internet><Interventional radiology><Intracellular Communication and Signaling><Investigational Drugs><Investigational New Drugs><Investigational Therapies><Investigational Treatments><Investigators><Joints><Laboratories><Lead><Leadership><Letters><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Medication><Mentors><Mentorship><Methodology><Minority Groups><Minority People><Minority Population><Minority individual><Molecular><Molecular Target><Monitor><Multimodal Therapy><Multimodal Treatment><NCI Organization><National Cancer Institute><Normal Tissue><Normal tissue morphology><Organizational Affiliation><Outcome><Pathology><Patient Selection><Patients><Pb element><Pharmaceutical Preparations><Pharmacodynamics><Pharmacogenomics><Pharmacokinetics><Pharmacology><Phase><Phase 4 Clinical Trials><Phase IV Clinical Trials><Policies><Preclinical data><Prediction of Response to Therapy><Principal Investigator><Procedures><Productivity><Protocol><Protocol Screening><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Research Personnel><Research Resources><Researchers><Resources><Safety><Science><Signal Transduction><Signal Transduction Pathway><Signal Transduction Systems><Signaling><Site><Specialty><Therapeutic><Time><Toxic effect><Toxicities><Translational Research><Translational Science><Tumor Cell><U-Series Cooperative Agreements><Universities><Unscheduled DNA Synthesis><Validation><Veins><WWW><anti-cancer therapy><bio-markers><biologic marker><biological signal transduction><biomarker><cancer immunology><cancer microenvironment><cancer therapy><cancer-directed therapy><cancers that are rare><career><career development><combination therapy><combined modality treatment><combined treatment><conference><convention><design><designing><developmental><drug/agent><early clinical trial><early phase clinical trial><early phase trial><experimental therapeutic agents><experimental therapeutics><heavy metal Pb><heavy metal lead><histories><imaging><immune-oncology><immuno oncology><immunology oncology><improved><innovate><innovation><innovative><insight><malignancy><medical specialties><meeting><meetings><member><minority patient><multi-modal therapy><multi-modal treatment><multidisciplinary><neoplasm immunology><neoplasm/cancer><neoplastic cell><new anti-cancer agent><new anticancer agent><new anticancer drug><new antineoplastic><new cancer drug><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><non-invasive imaging><noninvasive imaging><novel><novel anti-cancer agent><novel anti-cancer drug><novel anticancer agent><novel anticancer drug><novel antineoplastic><novel cancer drug><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><oncoimmunology><patients from minority><patients of minority><post treatment><pre-clinical><preclinical><preclinical findings><preclinical information><predict therapeutic response><predict therapy response><programs><rare cancer><rare malignancy><rare tumor><summit><symposia><symposium><therapy prediction><timeline><translation research><translational investigation><translational investigator><translational researcher><translational scientist><treatment prediction><treatment response prediction><tumor><tumor immunology><tumor microenvironment><validations><web><world wide web>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

VALERIE L DURKALSKI

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,742,655
FY 2025

Project Title

A Multicenter Randomized Controlled Trial of Surveillance versus. Endoscopic Therapy for Barretts Esophagus with Low-grade Dysplasia: The SURVENT Trial

Grant Number:

5U01DK129191-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2022

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract Barrett's esophagus (BE), a metaplastic change of the esophageal lining associated with chronic gastroesophageal reflux disease, is the only known precursor to esophageal adenocarcinoma (EAC). EAC is one of the most rapidly increasing cancers in the United States, frequently...

Research Terms

<21+ years old><Achievement><Achievement Attainment><Acid Reflux><Active Follow-up><Address><Adenocarcinoma of the Esophagus><Adult><Adult Human><Affect><Antioncogene Protein p53><Area><Barrett Esophagus><Barrett Syndrome><Barrett Ulcer><Biological><Biological Markers><Biopsy><Cancers><Care Givers><Caregivers><Caring><Categories><Cellular Tumor Antigen P53><Chronic><Clinical><Clinical Management><Clinical Markers><Clinical Trials><Clinical Trials Data Monitoring Committees><Columnar Epithelial-Lined Lower Esophagus><Columnar-Lined Esophagus><Complication><Conduct Clinical Trials><Data><Data Monitoring Committees><Data and Safety Monitoring Boards><Detection><Diagnosis><Disease><Disorder><Dysplasia><Effectiveness><Eligibility><Eligibility Determination><Emotional well being><Endoscopy><Enrollment><Ensure><Equipoise><Esophageal Adenocarcinoma><Esophageal Cancer><Esophageal Reflux><Esophageal mucous membrane><Esophagus><Esophagus Cancer><Europe><Feedback><Feels well><Forcep><Funding><Future><GERD><Gastro-oesophageal Reflux><Gastroesophageal Reflux><Gastroesophageal reflux disease><Goals><Grant><Guidelines><Health><Health Care><High grade dysplasia><Histologic><Histologically><Image><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Incidence><Institute of Medicine><Institute of Medicine (U.S.)><Knowledge><Lead><Malignant Esophageal Neoplasm><Malignant Esophageal Tumor><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Esophagus><Malignant neoplasm of esophagus><Metaplasia><Metaplastic Change><Modality><Molecular><Morbidity><Morbidity - disease rate><Mucosa><Mucosal Tissue><Mucous Membrane><NAS/IOM><Normal mental condition><Normal mental state><Normal psyche><Oncoprotein p53><P53><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pb element><Peer Review><Periodicals><Phosphoprotein P53><Phosphoprotein pp53><Population><Position><Positioning Attribute><Precancerous Conditions><Premalignant Condition><Premalignant State><Principal Investigator><Procedures><Protein TP53><Protocol><Protocol Screening><Protocols documentation><Psychological Well Being><Public Health><QOL><QOL improvement><Quality of life><Randomization trial><Randomized><Randomized, Controlled Trials><Research><Research Priority><Risk><Safety Monitoring Boards><Sample Size><Sampling><Sense of well-being><Specific qualifier value><Specified><Survival Rate><TP53><TP53 gene><TRP53><Time><Translational Research><Translational Science><Treatment Cost><Tumor Protein p53><Tumor Protein p53 Gene><United States><Well in self><Work><active followup><adulthood><arm><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker array><biomarker panel><biomarker selection><biorepository><cancer progression><care for patients><care of patients><caring for patients><clinical biomarkers><clinical relevance><clinically relevant><clinically useful biomarkers><cohort><common treatment><comparative effectiveness><comparative safety><compare effectiveness><cost><design><designing><dyscrasia><emotional wellbeing><emotional wellness><endoscopic imaging><enroll><esophageal intestinal metaplasia><esophageal mucosa><experience><follow up><follow-up><followed up><followup><health related quality of life><heavy metal Pb><heavy metal lead><high risk><imaging><improved><improvements in QOL><improvements in quality of life><inclusion criteria><innovate><innovation><innovative><malignancy><marker panel><mental well-being><mental wellbeing><mental wellness><multidisciplinary><neoplasm progression><neoplasm/cancer><neoplastic progression><oesophageal cancer><p53 Antigen><p53 Genes><p53 Tumor Suppressor><patient centered><patient oriented><patient oriented outcomes><patient population><periodic><periodical><precancerous state><predict clinical outcome><primary end point><primary endpoint><protein p53><psychological wellbeing><psychological wellness><public health relevance><quality of life improvement><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><risk stratification><self wellness><sense of wellbeing><standard of care><stratify risk><translation research><translational investigation><treatment center><treatment group><tumor progression>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

NICHOLAS J SHAHEEN

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,742,655
FY 2025

Project Title

A Multicenter Randomized Controlled Trial of Surveillance versus. Endoscopic Therapy for Barretts Esophagus with Low-grade Dysplasia: The SURVENT Trial

Grant Number:

5U01DK129191-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2022

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract Barrett's esophagus (BE), a metaplastic change of the esophageal lining associated with chronic gastroesophageal reflux disease, is the only known precursor to esophageal adenocarcinoma (EAC). EAC is one of the most rapidly increasing cancers in the United States, frequently...

Research Terms

<21+ years old><Achievement><Achievement Attainment><Acid Reflux><Active Follow-up><Address><Adenocarcinoma of the Esophagus><Adult><Adult Human><Affect><Antioncogene Protein p53><Area><Barrett Esophagus><Barrett Syndrome><Barrett Ulcer><Biological><Biological Markers><Biopsy><Cancers><Care Givers><Caregivers><Caring><Categories><Cellular Tumor Antigen P53><Chronic><Clinical><Clinical Management><Clinical Markers><Clinical Trials><Clinical Trials Data Monitoring Committees><Columnar Epithelial-Lined Lower Esophagus><Columnar-Lined Esophagus><Complication><Conduct Clinical Trials><Data><Data Monitoring Committees><Data and Safety Monitoring Boards><Detection><Diagnosis><Disease><Disorder><Dysplasia><Effectiveness><Eligibility><Eligibility Determination><Emotional well being><Endoscopy><Enrollment><Ensure><Equipoise><Esophageal Adenocarcinoma><Esophageal Cancer><Esophageal Reflux><Esophageal mucous membrane><Esophagus><Esophagus Cancer><Europe><Feedback><Feels well><Forcep><Funding><Future><GERD><Gastro-oesophageal Reflux><Gastroesophageal Reflux><Gastroesophageal reflux disease><Goals><Grant><Guidelines><Health><Health Care><High grade dysplasia><Histologic><Histologically><Image><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Incidence><Institute of Medicine><Institute of Medicine (U.S.)><Knowledge><Lead><Malignant Esophageal Neoplasm><Malignant Esophageal Tumor><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Esophagus><Malignant neoplasm of esophagus><Metaplasia><Metaplastic Change><Modality><Molecular><Morbidity><Morbidity - disease rate><Mucosa><Mucosal Tissue><Mucous Membrane><NAS/IOM><Normal mental condition><Normal mental state><Normal psyche><Oncoprotein p53><P53><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pb element><Peer Review><Periodicals><Phosphoprotein P53><Phosphoprotein pp53><Population><Position><Positioning Attribute><Precancerous Conditions><Premalignant Condition><Premalignant State><Principal Investigator><Procedures><Protein TP53><Protocol><Protocol Screening><Protocols documentation><Psychological Well Being><Public Health><QOL><QOL improvement><Quality of life><Randomization trial><Randomized><Randomized, Controlled Trials><Research><Research Priority><Risk><Safety Monitoring Boards><Sample Size><Sampling><Sense of well-being><Specific qualifier value><Specified><Survival Rate><TP53><TP53 gene><TRP53><Time><Translational Research><Translational Science><Treatment Cost><Tumor Protein p53><Tumor Protein p53 Gene><United States><Well in self><Work><active followup><adulthood><arm><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker array><biomarker panel><biomarker selection><biorepository><cancer progression><care for patients><care of patients><caring for patients><clinical biomarkers><clinical relevance><clinically relevant><clinically useful biomarkers><cohort><common treatment><comparative effectiveness><comparative safety><compare effectiveness><cost><design><designing><dyscrasia><emotional wellbeing><emotional wellness><endoscopic imaging><enroll><esophageal intestinal metaplasia><esophageal mucosa><experience><follow up><follow-up><followed up><followup><health related quality of life><heavy metal Pb><heavy metal lead><high risk><imaging><improved><improvements in QOL><improvements in quality of life><inclusion criteria><innovate><innovation><innovative><malignancy><marker panel><mental well-being><mental wellbeing><mental wellness><multidisciplinary><neoplasm progression><neoplasm/cancer><neoplastic progression><oesophageal cancer><p53 Antigen><p53 Genes><p53 Tumor Suppressor><patient centered><patient oriented><patient oriented outcomes><patient population><periodic><periodical><precancerous state><predict clinical outcome><primary end point><primary endpoint><protein p53><psychological wellbeing><psychological wellness><public health relevance><quality of life improvement><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><risk stratification><self wellness><sense of wellbeing><standard of care><stratify risk><translation research><translational investigation><treatment center><treatment group><tumor progression>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RHONDA F SOUZA

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,742,655
FY 2025

Project Title

A Multicenter Randomized Controlled Trial of Surveillance versus. Endoscopic Therapy for Barretts Esophagus with Low-grade Dysplasia: The SURVENT Trial

Grant Number:

5U01DK129191-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2022

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract Barrett's esophagus (BE), a metaplastic change of the esophageal lining associated with chronic gastroesophageal reflux disease, is the only known precursor to esophageal adenocarcinoma (EAC). EAC is one of the most rapidly increasing cancers in the United States, frequently...

Research Terms

<21+ years old><Achievement><Achievement Attainment><Acid Reflux><Active Follow-up><Address><Adenocarcinoma of the Esophagus><Adult><Adult Human><Affect><Antioncogene Protein p53><Area><Barrett Esophagus><Barrett Syndrome><Barrett Ulcer><Biological><Biological Markers><Biopsy><Cancers><Care Givers><Caregivers><Caring><Categories><Cellular Tumor Antigen P53><Chronic><Clinical><Clinical Management><Clinical Markers><Clinical Trials><Clinical Trials Data Monitoring Committees><Columnar Epithelial-Lined Lower Esophagus><Columnar-Lined Esophagus><Complication><Conduct Clinical Trials><Data><Data Monitoring Committees><Data and Safety Monitoring Boards><Detection><Diagnosis><Disease><Disorder><Dysplasia><Effectiveness><Eligibility><Eligibility Determination><Emotional well being><Endoscopy><Enrollment><Ensure><Equipoise><Esophageal Adenocarcinoma><Esophageal Cancer><Esophageal Reflux><Esophageal mucous membrane><Esophagus><Esophagus Cancer><Europe><Feedback><Feels well><Forcep><Funding><Future><GERD><Gastro-oesophageal Reflux><Gastroesophageal Reflux><Gastroesophageal reflux disease><Goals><Grant><Guidelines><Health><Health Care><High grade dysplasia><Histologic><Histologically><Image><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Incidence><Institute of Medicine><Institute of Medicine (U.S.)><Knowledge><Lead><Malignant Esophageal Neoplasm><Malignant Esophageal Tumor><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Esophagus><Malignant neoplasm of esophagus><Metaplasia><Metaplastic Change><Modality><Molecular><Morbidity><Morbidity - disease rate><Mucosa><Mucosal Tissue><Mucous Membrane><NAS/IOM><Normal mental condition><Normal mental state><Normal psyche><Oncoprotein p53><P53><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pb element><Peer Review><Periodicals><Phosphoprotein P53><Phosphoprotein pp53><Population><Position><Positioning Attribute><Precancerous Conditions><Premalignant Condition><Premalignant State><Principal Investigator><Procedures><Protein TP53><Protocol><Protocol Screening><Protocols documentation><Psychological Well Being><Public Health><QOL><QOL improvement><Quality of life><Randomization trial><Randomized><Randomized, Controlled Trials><Research><Research Priority><Risk><Safety Monitoring Boards><Sample Size><Sampling><Sense of well-being><Specific qualifier value><Specified><Survival Rate><TP53><TP53 gene><TRP53><Time><Translational Research><Translational Science><Treatment Cost><Tumor Protein p53><Tumor Protein p53 Gene><United States><Well in self><Work><active followup><adulthood><arm><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker array><biomarker panel><biomarker selection><biorepository><cancer progression><care for patients><care of patients><caring for patients><clinical biomarkers><clinical relevance><clinically relevant><clinically useful biomarkers><cohort><common treatment><comparative effectiveness><comparative safety><compare effectiveness><cost><design><designing><dyscrasia><emotional wellbeing><emotional wellness><endoscopic imaging><enroll><esophageal intestinal metaplasia><esophageal mucosa><experience><follow up><follow-up><followed up><followup><health related quality of life><heavy metal Pb><heavy metal lead><high risk><imaging><improved><improvements in QOL><improvements in quality of life><inclusion criteria><innovate><innovation><innovative><malignancy><marker panel><mental well-being><mental wellbeing><mental wellness><multidisciplinary><neoplasm progression><neoplasm/cancer><neoplastic progression><oesophageal cancer><p53 Antigen><p53 Genes><p53 Tumor Suppressor><patient centered><patient oriented><patient oriented outcomes><patient population><periodic><periodical><precancerous state><predict clinical outcome><primary end point><primary endpoint><protein p53><psychological wellbeing><psychological wellness><public health relevance><quality of life improvement><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><risk stratification><self wellness><sense of wellbeing><standard of care><stratify risk><translation research><translational investigation><treatment center><treatment group><tumor progression>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sachin Wani

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,742,655
FY 2025

Project Title

A Multicenter Randomized Controlled Trial of Surveillance versus. Endoscopic Therapy for Barretts Esophagus with Low-grade Dysplasia: The SURVENT Trial

Grant Number:

5U01DK129191-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2022

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract Barrett's esophagus (BE), a metaplastic change of the esophageal lining associated with chronic gastroesophageal reflux disease, is the only known precursor to esophageal adenocarcinoma (EAC). EAC is one of the most rapidly increasing cancers in the United States, frequently...

Research Terms

<21+ years old><Achievement><Achievement Attainment><Acid Reflux><Active Follow-up><Address><Adenocarcinoma of the Esophagus><Adult><Adult Human><Affect><Antioncogene Protein p53><Area><Barrett Esophagus><Barrett Syndrome><Barrett Ulcer><Biological><Biological Markers><Biopsy><Cancers><Care Givers><Caregivers><Caring><Categories><Cellular Tumor Antigen P53><Chronic><Clinical><Clinical Management><Clinical Markers><Clinical Trials><Clinical Trials Data Monitoring Committees><Columnar Epithelial-Lined Lower Esophagus><Columnar-Lined Esophagus><Complication><Conduct Clinical Trials><Data><Data Monitoring Committees><Data and Safety Monitoring Boards><Detection><Diagnosis><Disease><Disorder><Dysplasia><Effectiveness><Eligibility><Eligibility Determination><Emotional well being><Endoscopy><Enrollment><Ensure><Equipoise><Esophageal Adenocarcinoma><Esophageal Cancer><Esophageal Reflux><Esophageal mucous membrane><Esophagus><Esophagus Cancer><Europe><Feedback><Feels well><Forcep><Funding><Future><GERD><Gastro-oesophageal Reflux><Gastroesophageal Reflux><Gastroesophageal reflux disease><Goals><Grant><Guidelines><Health><Health Care><High grade dysplasia><Histologic><Histologically><Image><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Incidence><Institute of Medicine><Institute of Medicine (U.S.)><Knowledge><Lead><Malignant Esophageal Neoplasm><Malignant Esophageal Tumor><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Esophagus><Malignant neoplasm of esophagus><Metaplasia><Metaplastic Change><Modality><Molecular><Morbidity><Morbidity - disease rate><Mucosa><Mucosal Tissue><Mucous Membrane><NAS/IOM><Normal mental condition><Normal mental state><Normal psyche><Oncoprotein p53><P53><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pb element><Peer Review><Periodicals><Phosphoprotein P53><Phosphoprotein pp53><Population><Position><Positioning Attribute><Precancerous Conditions><Premalignant Condition><Premalignant State><Principal Investigator><Procedures><Protein TP53><Protocol><Protocol Screening><Protocols documentation><Psychological Well Being><Public Health><QOL><QOL improvement><Quality of life><Randomization trial><Randomized><Randomized, Controlled Trials><Research><Research Priority><Risk><Safety Monitoring Boards><Sample Size><Sampling><Sense of well-being><Specific qualifier value><Specified><Survival Rate><TP53><TP53 gene><TRP53><Time><Translational Research><Translational Science><Treatment Cost><Tumor Protein p53><Tumor Protein p53 Gene><United States><Well in self><Work><active followup><adulthood><arm><bio-markers><biobank><biologic><biologic marker><biomarker><biomarker array><biomarker panel><biomarker selection><biorepository><cancer progression><care for patients><care of patients><caring for patients><clinical biomarkers><clinical relevance><clinically relevant><clinically useful biomarkers><cohort><common treatment><comparative effectiveness><comparative safety><compare effectiveness><cost><design><designing><dyscrasia><emotional wellbeing><emotional wellness><endoscopic imaging><enroll><esophageal intestinal metaplasia><esophageal mucosa><experience><follow up><follow-up><followed up><followup><health related quality of life><heavy metal Pb><heavy metal lead><high risk><imaging><improved><improvements in QOL><improvements in quality of life><inclusion criteria><innovate><innovation><innovative><malignancy><marker panel><mental well-being><mental wellbeing><mental wellness><multidisciplinary><neoplasm progression><neoplasm/cancer><neoplastic progression><oesophageal cancer><p53 Antigen><p53 Genes><p53 Tumor Suppressor><patient centered><patient oriented><patient oriented outcomes><patient population><periodic><periodical><precancerous state><predict clinical outcome><primary end point><primary endpoint><protein p53><psychological wellbeing><psychological wellness><public health relevance><quality of life improvement><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><risk stratification><self wellness><sense of wellbeing><standard of care><stratify risk><translation research><translational investigation><treatment center><treatment group><tumor progression>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Doratha Armenthus Byrd

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,724,414
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

5U01CA206110-10

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jane C. Figueiredo

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,724,414
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

5U01CA206110-10

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Biljana Gigic

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,724,414
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

5U01CA206110-10

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DAVID SHIBATA

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,724,414
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

5U01CA206110-10

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Adetunji T Toriola

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,724,414
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

5U01CA206110-10

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CORNELIA M ULRICH

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,724,414
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

5U01CA206110-10

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christine Marie Durand

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,683,861
FY 2025

Project Title

Expanding HOPE Liver Transplantation: Understanding Opportunistic Infection and Cancer Risk

Grant Number:

2U01AI138897-06A1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2018

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Early studies of liver transplantation (LT) from donors with HIV to recipients with HIV (HIV D+/R+) under the HIV Organ Policy Equity (HOPE) Act have shown acceptable transplant outcomes, supporting safety and feasibility, and prompting the Secretary of Health and Human Services to publish a federal...

Research Terms

<AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Active Follow-up><Allografting><Antibodies><Aspergillus><Assay><Bioassay><Biological Assay><Blood Plasma><CD4 Lymphocyte Count><CD4+ Cell Counts><CD4+ Counts><CITE sequencing><CITE-seq><CITEseq><CMV><Cancers><Candida><Cell Body><Cells><Cellular Indexing of Transcriptomes and Epitopes by Sequencing><Chemotactic Cytokines><Clinical Trials><Collaborations><Collection><Cytomegalovirus><DNA><Data><Deoxyribonucleic Acid><Department of Health and Human Services><Donor person><Equity><Event><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Functional Metagenomics><Graft Survival><Grant><HBV disease><HCMV><HCV><HCV Viremia><HCV disease><HHV-8><HHV8><HIV><HPV><Health><HepB><Hepatic Transplantation><Hepatitis B><Hepatitis C><Hepatitis C Viremia><Hepatitis C Virus Viremia><Hepatitis C virus><Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted><Hepatitus C><High Prevalence><Homologous Chemotactic Cytokines><Human><Human Herpesvirus 8><Human Immunodeficiency Viruses><Human Papilloma Virus><Human Papillomavirus><Immune><Immune Cell Activation><Immune Precipitation><Immune response><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunology procedure><Immunoprecipitation><Impairment><Incidence><Infection><Infectious Human Wart Virus><Inflammation><Infrastructure><Intercrines><Intervention><KSHV><Kaposi Sarcoma-Associated Herpes Virus><Kaposi Sarcoma-Associated Herpesvirus><Kaposi sarcoma associated virus><Kaposi sarcoma herpes virus><Kaposi's sarcoma (KS)-associated herpesvirus><Knowledge><LAV-HTLV-III><Liver><Liver Grafting><Liver Transplant><Long-term Follow-up><Lymphadenopathy-Associated Virus><Malignant Neoplasms><Malignant Tumor><Measures><Metagenomics><Modeling><Modern Man><Molecular><Monilia><Monitor><Multi-center studies><Multicenter Studies><NCI Organization><National Cancer Institute><Negative Finding><Opportunistic Infections><Organ><Organ Procurements><Outcome><Outcome Measure><Parents><Pathway interactions><Patients><Phage Display><Plasma><Plasma Serum><Policies><Prophylactic treatment><Prophylaxis><Publishing><Research><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><SIS cytokines><Safety><Salivary Gland Viruses><Sample Size><Services><Staining method><Stains><T cell response><T4 Lymphocyte Count><Time><Transplant Recipients><Transplantation><United States Department of Health and Human Services><United States Dept. of Health and Human Services><Viral><Viral Diseases><Viral Hepatitis B><Viremia><Virus><Virus Activation><Virus Diseases><Virus Induction><Virus-HHV8><Virus-HIV><Virus-Related Malignancy><Virus-Related Malignant Neoplasm><Wait Time><Work><active followup><antiretroviral therapy><antiretroviral treatment><attributable risk><cancer risk><cellular indexing of transcriptomes and epitopes by single cell sequencing><chemoattractant cytokine><chemokine><clinical care><clinical decision-making><co-infection><cohort><coinfection><cytokine><cytomegalovirus group><data management><data registry><design><designing><detection assay><experience><flow cytophotometry><follow up><follow-up><followed up><followup><hep B><hep C><hepC><hepatic body system><hepatic organ system><hepatitis B virus disease><hepatitis non A non B><host response><immune activation><immune system response><immunologic assay><immunologic assay/test><immunoresponse><improved outcome><infection risk><kaposi's sarcoma herpesvirus><kaposi's sarcoma-associated human herpesvirus><liver transplantation><long-term followup><malignancy><measurable outcome><neoplasm/cancer><non A, non B hepatitis><non-A, non-B hepatitis><novel><operation><operations><outcome measurement><parent><pathogen><pathway><primary outcome><response><risk mitigation><safety and feasibility><success><transplant><transplant centers><transplant donor><transplant patient><viraemia><viral activation><viral associated cancer><viral associated malignancy><viral associated malignant neoplasm><viral hepatitis C><viral induced cancer><viral induced malignancy><viral induced malignant neoplasm><viral induction><viral infection><viral microbiome><viral related cancer><viral related malignancy><viral related malignant neoplasm><viral sepsis><virome><virus associated cancer><virus associated malignancy><virus associated malignant neoplasm><virus induced cancer><virus induced malignancy><virus induced malignant neoplasm><virus infection><virus related cancer><virus-induced disease><virusemia><wart virus>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DORRY L. SEGEV

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,683,861
FY 2025

Project Title

Expanding HOPE Liver Transplantation: Understanding Opportunistic Infection and Cancer Risk

Grant Number:

2U01AI138897-06A1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2018

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Early studies of liver transplantation (LT) from donors with HIV to recipients with HIV (HIV D+/R+) under the HIV Organ Policy Equity (HOPE) Act have shown acceptable transplant outcomes, supporting safety and feasibility, and prompting the Secretary of Health and Human Services to publish a federal...

Research Terms

<AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Active Follow-up><Allografting><Antibodies><Aspergillus><Assay><Bioassay><Biological Assay><Blood Plasma><CD4 Lymphocyte Count><CD4+ Cell Counts><CD4+ Counts><CITE sequencing><CITE-seq><CITEseq><CMV><Cancers><Candida><Cell Body><Cells><Cellular Indexing of Transcriptomes and Epitopes by Sequencing><Chemotactic Cytokines><Clinical Trials><Collaborations><Collection><Cytomegalovirus><DNA><Data><Deoxyribonucleic Acid><Department of Health and Human Services><Donor person><Equity><Event><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Functional Metagenomics><Graft Survival><Grant><HBV disease><HCMV><HCV><HCV Viremia><HCV disease><HHV-8><HHV8><HIV><HPV><Health><HepB><Hepatic Transplantation><Hepatitis B><Hepatitis C><Hepatitis C Viremia><Hepatitis C Virus Viremia><Hepatitis C virus><Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted><Hepatitus C><High Prevalence><Homologous Chemotactic Cytokines><Human><Human Herpesvirus 8><Human Immunodeficiency Viruses><Human Papilloma Virus><Human Papillomavirus><Immune><Immune Cell Activation><Immune Precipitation><Immune response><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunology procedure><Immunoprecipitation><Impairment><Incidence><Infection><Infectious Human Wart Virus><Inflammation><Infrastructure><Intercrines><Intervention><KSHV><Kaposi Sarcoma-Associated Herpes Virus><Kaposi Sarcoma-Associated Herpesvirus><Kaposi sarcoma associated virus><Kaposi sarcoma herpes virus><Kaposi's sarcoma (KS)-associated herpesvirus><Knowledge><LAV-HTLV-III><Liver><Liver Grafting><Liver Transplant><Long-term Follow-up><Lymphadenopathy-Associated Virus><Malignant Neoplasms><Malignant Tumor><Measures><Metagenomics><Modeling><Modern Man><Molecular><Monilia><Monitor><Multi-center studies><Multicenter Studies><NCI Organization><National Cancer Institute><Negative Finding><Opportunistic Infections><Organ><Organ Procurements><Outcome><Outcome Measure><Parents><Pathway interactions><Patients><Phage Display><Plasma><Plasma Serum><Policies><Prophylactic treatment><Prophylaxis><Publishing><Research><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><SIS cytokines><Safety><Salivary Gland Viruses><Sample Size><Services><Staining method><Stains><T cell response><T4 Lymphocyte Count><Time><Transplant Recipients><Transplantation><United States Department of Health and Human Services><United States Dept. of Health and Human Services><Viral><Viral Diseases><Viral Hepatitis B><Viremia><Virus><Virus Activation><Virus Diseases><Virus Induction><Virus-HHV8><Virus-HIV><Virus-Related Malignancy><Virus-Related Malignant Neoplasm><Wait Time><Work><active followup><antiretroviral therapy><antiretroviral treatment><attributable risk><cancer risk><cellular indexing of transcriptomes and epitopes by single cell sequencing><chemoattractant cytokine><chemokine><clinical care><clinical decision-making><co-infection><cohort><coinfection><cytokine><cytomegalovirus group><data management><data registry><design><designing><detection assay><experience><flow cytophotometry><follow up><follow-up><followed up><followup><hep B><hep C><hepC><hepatic body system><hepatic organ system><hepatitis B virus disease><hepatitis non A non B><host response><immune activation><immune system response><immunologic assay><immunologic assay/test><immunoresponse><improved outcome><infection risk><kaposi's sarcoma herpesvirus><kaposi's sarcoma-associated human herpesvirus><liver transplantation><long-term followup><malignancy><measurable outcome><neoplasm/cancer><non A, non B hepatitis><non-A, non-B hepatitis><novel><operation><operations><outcome measurement><parent><pathogen><pathway><primary outcome><response><risk mitigation><safety and feasibility><success><transplant><transplant centers><transplant donor><transplant patient><viraemia><viral activation><viral associated cancer><viral associated malignancy><viral associated malignant neoplasm><viral hepatitis C><viral induced cancer><viral induced malignancy><viral induced malignant neoplasm><viral induction><viral infection><viral microbiome><viral related cancer><viral related malignancy><viral related malignant neoplasm><viral sepsis><virome><virus associated cancer><virus associated malignancy><virus associated malignant neoplasm><virus induced cancer><virus induced malignancy><virus induced malignant neoplasm><virus infection><virus related cancer><virus-induced disease><virusemia><wart virus>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

AARON A TOBIAN

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,683,861
FY 2025

Project Title

Expanding HOPE Liver Transplantation: Understanding Opportunistic Infection and Cancer Risk

Grant Number:

2U01AI138897-06A1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2018

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Early studies of liver transplantation (LT) from donors with HIV to recipients with HIV (HIV D+/R+) under the HIV Organ Policy Equity (HOPE) Act have shown acceptable transplant outcomes, supporting safety and feasibility, and prompting the Secretary of Health and Human Services to publish a federal...

Research Terms

<AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Active Follow-up><Allografting><Antibodies><Aspergillus><Assay><Bioassay><Biological Assay><Blood Plasma><CD4 Lymphocyte Count><CD4+ Cell Counts><CD4+ Counts><CITE sequencing><CITE-seq><CITEseq><CMV><Cancers><Candida><Cell Body><Cells><Cellular Indexing of Transcriptomes and Epitopes by Sequencing><Chemotactic Cytokines><Clinical Trials><Collaborations><Collection><Cytomegalovirus><DNA><Data><Deoxyribonucleic Acid><Department of Health and Human Services><Donor person><Equity><Event><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Functional Metagenomics><Graft Survival><Grant><HBV disease><HCMV><HCV><HCV Viremia><HCV disease><HHV-8><HHV8><HIV><HPV><Health><HepB><Hepatic Transplantation><Hepatitis B><Hepatitis C><Hepatitis C Viremia><Hepatitis C Virus Viremia><Hepatitis C virus><Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted><Hepatitus C><High Prevalence><Homologous Chemotactic Cytokines><Human><Human Herpesvirus 8><Human Immunodeficiency Viruses><Human Papilloma Virus><Human Papillomavirus><Immune><Immune Cell Activation><Immune Precipitation><Immune response><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunology procedure><Immunoprecipitation><Impairment><Incidence><Infection><Infectious Human Wart Virus><Inflammation><Infrastructure><Intercrines><Intervention><KSHV><Kaposi Sarcoma-Associated Herpes Virus><Kaposi Sarcoma-Associated Herpesvirus><Kaposi sarcoma associated virus><Kaposi sarcoma herpes virus><Kaposi's sarcoma (KS)-associated herpesvirus><Knowledge><LAV-HTLV-III><Liver><Liver Grafting><Liver Transplant><Long-term Follow-up><Lymphadenopathy-Associated Virus><Malignant Neoplasms><Malignant Tumor><Measures><Metagenomics><Modeling><Modern Man><Molecular><Monilia><Monitor><Multi-center studies><Multicenter Studies><NCI Organization><National Cancer Institute><Negative Finding><Opportunistic Infections><Organ><Organ Procurements><Outcome><Outcome Measure><Parents><Pathway interactions><Patients><Phage Display><Plasma><Plasma Serum><Policies><Prophylactic treatment><Prophylaxis><Publishing><Research><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><SIS cytokines><Safety><Salivary Gland Viruses><Sample Size><Services><Staining method><Stains><T cell response><T4 Lymphocyte Count><Time><Transplant Recipients><Transplantation><United States Department of Health and Human Services><United States Dept. of Health and Human Services><Viral><Viral Diseases><Viral Hepatitis B><Viremia><Virus><Virus Activation><Virus Diseases><Virus Induction><Virus-HHV8><Virus-HIV><Virus-Related Malignancy><Virus-Related Malignant Neoplasm><Wait Time><Work><active followup><antiretroviral therapy><antiretroviral treatment><attributable risk><cancer risk><cellular indexing of transcriptomes and epitopes by single cell sequencing><chemoattractant cytokine><chemokine><clinical care><clinical decision-making><co-infection><cohort><coinfection><cytokine><cytomegalovirus group><data management><data registry><design><designing><detection assay><experience><flow cytophotometry><follow up><follow-up><followed up><followup><hep B><hep C><hepC><hepatic body system><hepatic organ system><hepatitis B virus disease><hepatitis non A non B><host response><immune activation><immune system response><immunologic assay><immunologic assay/test><immunoresponse><improved outcome><infection risk><kaposi's sarcoma herpesvirus><kaposi's sarcoma-associated human herpesvirus><liver transplantation><long-term followup><malignancy><measurable outcome><neoplasm/cancer><non A, non B hepatitis><non-A, non-B hepatitis><novel><operation><operations><outcome measurement><parent><pathogen><pathway><primary outcome><response><risk mitigation><safety and feasibility><success><transplant><transplant centers><transplant donor><transplant patient><viraemia><viral activation><viral associated cancer><viral associated malignancy><viral associated malignant neoplasm><viral hepatitis C><viral induced cancer><viral induced malignancy><viral induced malignant neoplasm><viral induction><viral infection><viral microbiome><viral related cancer><viral related malignancy><viral related malignant neoplasm><viral sepsis><virome><virus associated cancer><virus associated malignancy><virus associated malignant neoplasm><virus induced cancer><virus induced malignancy><virus induced malignant neoplasm><virus infection><virus related cancer><virus-induced disease><virusemia><wart virus>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lindsey Robert Baden

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,673,641
FY 2025

Project Title

Phase 1 study of a SARS-CoV-2 vaccine adjuvanted via controlled biodistribution of mRNA encoding spike protein and IL-12p70

Grant Number:

1U01AI191995-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2025

End Date:

7/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary mRNA-lipid nanoparticle (LNP)-based vaccines are an exciting platform that made advances in combating the pandemic viruses. However, currently licensed mRNA-LNP vaccines approaches are limited in their ability to induce long lived antibody durability, degree of protection varies by a...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><2019-nCoV S protein><2019-nCoV spike glycoprotein><2019-nCoV spike protein><2019-nCoV vaccine><21+ years old><Active Follow-up><Adjuvant><Adjuvanticity><Adult><Adult Human><Age><Antibodies><Antigenic Determinants><Antigens><B blood cells><B cell><B cells><B-Cell Epitopes><B-Cells><B-Lymphocyte Epitopes><B-Lymphocytes><B-cell><BNT 162b2><BNT162b2><Binding Determinants><Biodistribution><Biological><Blood><Blood Plasma><Blood Plasma Cell><Blood Reticuloendothelial System><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><CD8><CD8B><CD8B1><CD8B1 gene><COVID-19 S protein><COVID-19 spike><COVID-19 spike glycoprotein><COVID-19 spike protein><COVID-19 vaccine><COVID-19 virus><COVID19 virus><Cell Mediated Immunology><Cell-Mediated Immunity><Cellular Immunity><Clinical Evaluation><Clinical Testing><CoV-2><CoV2><Communicable Diseases><Data><Dose><Dryness><Early-Stage Clinical Trials><Edodekin Alfa><Encapsulated><Enrollment><Epitopes><Evaluation><Future><Gene Inactivation><Gene Silencing><Goals><Health><Homologous Sequences><Hour><Human><Humoral Immunities><IL-12><IL12><IgG1><IgG3><IgG4><Immune><Immune Cell Activation><Immune response><Immunes><Immunity><Immunization><Immunochemical Immunologic><Immunologic><Immunologic Subtyping><Immunological><Immunologically><Immunologics><Immunophenotyping><Impairment><Infectious Diseases><Infectious Disorder><Injections><Interleukin-12><Interleukins><Investigation><Kinetics><LYT3><Licensing><Lymph Node Reticuloendothelial System><Lymph node proper><Lymphatic nodes><Malaise><Maximal Tolerated Dose><Maximally Tolerated Dose><Maximum Tolerated Dose><Measurement><Measures><Messenger RNA><MicroRNAs><Modern Man><Molecular><Myocarditis><NKSF><Natural Killer Cell Stimulatory Factor><Older Population><Organ><Participant><Pathway interactions><Pfizer covid19 vaccine><Pfizer-BioNTech COVID-19 vaccine><Pfizer-BioNTech coronavirus disease 2019 vaccine><Pfizer/BioNTech vaccine><Phase 1 Clinical Trials><Phase I Clinical Trials><Phase I Study><Plasma><Plasma Cells><Plasma Serum><Plasmacytes><Proteins><Proteomics><Publishing><RNA vaccine><RNA-based vaccine><Randomized><Reticuloendothelial System, Serum, Plasma><Risk><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 S><SARS-CoV-2 S protein><SARS-CoV-2 spike><SARS-CoV-2 spike glycoprotein><SARS-CoV-2 spike protein><SARS-CoV-2 vaccine><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 vaccine><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Safety><Sample Size><Sampling><Seasons><Sequence Homologs><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 vaccine><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 S protein><Severe acute respiratory syndrome coronavirus 2 spike glycoprotein><Severe acute respiratory syndrome coronavirus 2 spike protein><Severe acute respiratory syndrome coronavirus 2 vaccine><Severe acute respiratory syndrome related corona virus 2><Site><Spottings><System><Technology><Tissues><Transcript><Translations><Vaccine Adjuvant><Vaccines><Viral><Viral Diseases><Virus><Virus Diseases><Wuhan coronavirus><active followup><adult youth><adulthood><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><antibody-based immunity><biologic><cardiac inflammation><clinical relevance><clinical test><clinically relevant><coronavirus disease 2019 S protein><coronavirus disease 2019 spike glycoprotein><coronavirus disease 2019 spike protein><coronavirus disease 2019 vaccine><coronavirus disease 2019 virus><coronavirus disease-19 vaccine><coronavirus disease-19 virus><design><designing><enroll><first in man><first-in-human><follow up><follow-up><followed up><followup><hCoV19><host response><immune activation><immune system response><immunization strategy><immunogen><immunogenicity><immunoresponse><improved><innovate><innovation><innovative><life span><lifespan><lipid based nanoparticle><lipid nanoparticle><lymph gland><lymph node biopsy><lymph nodes><lymphnodes><mRNA><mRNA Translation><mRNA lipid nano particle vaccine><mRNA vaccine><mRNA-LNP based vaccine><mRNA-LNP combination vaccines><mRNA-LNP vaccines><mRNA-based vaccine><miRNA><mouse model><murine model><nCoV vaccine><nCoV-19 vaccine><nCoV19 vaccine><nCoV2><next generation><non-human primate><nonhuman primate><novel><older adult><older adulthood><older groups><older individuals><older person><pandemic virus><pathway><peripheral blood><phase 1 study><phase I protocol><plasmocyte><population aging><primary outcome><randomisation><randomization><randomly assigned><research clinical testing><respiratory><response><safety assessment><safety testing><spike proteins on SARS-CoV-2><transcriptional silencing><transcriptomics><translation><unpublished works><vaccination strategy><vaccine against 2019-nCov><vaccine against COVID-19><vaccine against SARS-CoV-2><vaccine against SARS-coronavirus-2><vaccine against Severe Acute Respiratory Syndrome CoV 2><vaccine against Severe acute respiratory syndrome coronavirus 2><vaccine candidate><vaccine candidates against SARS-CoV-2><vaccine for novel coronavirus><vaccine strategy><vaccines preventing COVID><vaccines to prevent COVID><viral infection><virus infection><virus-induced disease><young adult><young adult age><young adulthood>
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David James Dowling

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,673,641
FY 2025

Project Title

Phase 1 study of a SARS-CoV-2 vaccine adjuvanted via controlled biodistribution of mRNA encoding spike protein and IL-12p70

Grant Number:

1U01AI191995-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2025

End Date:

7/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary mRNA-lipid nanoparticle (LNP)-based vaccines are an exciting platform that made advances in combating the pandemic viruses. However, currently licensed mRNA-LNP vaccines approaches are limited in their ability to induce long lived antibody durability, degree of protection varies by a...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><2019-nCoV S protein><2019-nCoV spike glycoprotein><2019-nCoV spike protein><2019-nCoV vaccine><21+ years old><Active Follow-up><Adjuvant><Adjuvanticity><Adult><Adult Human><Age><Antibodies><Antigenic Determinants><Antigens><B blood cells><B cell><B cells><B-Cell Epitopes><B-Cells><B-Lymphocyte Epitopes><B-Lymphocytes><B-cell><BNT 162b2><BNT162b2><Binding Determinants><Biodistribution><Biological><Blood><Blood Plasma><Blood Plasma Cell><Blood Reticuloendothelial System><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><CD8><CD8B><CD8B1><CD8B1 gene><COVID-19 S protein><COVID-19 spike><COVID-19 spike glycoprotein><COVID-19 spike protein><COVID-19 vaccine><COVID-19 virus><COVID19 virus><Cell Mediated Immunology><Cell-Mediated Immunity><Cellular Immunity><Clinical Evaluation><Clinical Testing><CoV-2><CoV2><Communicable Diseases><Data><Dose><Dryness><Early-Stage Clinical Trials><Edodekin Alfa><Encapsulated><Enrollment><Epitopes><Evaluation><Future><Gene Inactivation><Gene Silencing><Goals><Health><Homologous Sequences><Hour><Human><Humoral Immunities><IL-12><IL12><IgG1><IgG3><IgG4><Immune><Immune Cell Activation><Immune response><Immunes><Immunity><Immunization><Immunochemical Immunologic><Immunologic><Immunologic Subtyping><Immunological><Immunologically><Immunologics><Immunophenotyping><Impairment><Infectious Diseases><Infectious Disorder><Injections><Interleukin-12><Interleukins><Investigation><Kinetics><LYT3><Licensing><Lymph Node Reticuloendothelial System><Lymph node proper><Lymphatic nodes><Malaise><Maximal Tolerated Dose><Maximally Tolerated Dose><Maximum Tolerated Dose><Measurement><Measures><Messenger RNA><MicroRNAs><Modern Man><Molecular><Myocarditis><NKSF><Natural Killer Cell Stimulatory Factor><Older Population><Organ><Participant><Pathway interactions><Pfizer covid19 vaccine><Pfizer-BioNTech COVID-19 vaccine><Pfizer-BioNTech coronavirus disease 2019 vaccine><Pfizer/BioNTech vaccine><Phase 1 Clinical Trials><Phase I Clinical Trials><Phase I Study><Plasma><Plasma Cells><Plasma Serum><Plasmacytes><Proteins><Proteomics><Publishing><RNA vaccine><RNA-based vaccine><Randomized><Reticuloendothelial System, Serum, Plasma><Risk><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 S><SARS-CoV-2 S protein><SARS-CoV-2 spike><SARS-CoV-2 spike glycoprotein><SARS-CoV-2 spike protein><SARS-CoV-2 vaccine><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 vaccine><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Safety><Sample Size><Sampling><Seasons><Sequence Homologs><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 vaccine><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 S protein><Severe acute respiratory syndrome coronavirus 2 spike glycoprotein><Severe acute respiratory syndrome coronavirus 2 spike protein><Severe acute respiratory syndrome coronavirus 2 vaccine><Severe acute respiratory syndrome related corona virus 2><Site><Spottings><System><Technology><Tissues><Transcript><Translations><Vaccine Adjuvant><Vaccines><Viral><Viral Diseases><Virus><Virus Diseases><Wuhan coronavirus><active followup><adult youth><adulthood><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><antibody-based immunity><biologic><cardiac inflammation><clinical relevance><clinical test><clinically relevant><coronavirus disease 2019 S protein><coronavirus disease 2019 spike glycoprotein><coronavirus disease 2019 spike protein><coronavirus disease 2019 vaccine><coronavirus disease 2019 virus><coronavirus disease-19 vaccine><coronavirus disease-19 virus><design><designing><enroll><first in man><first-in-human><follow up><follow-up><followed up><followup><hCoV19><host response><immune activation><immune system response><immunization strategy><immunogen><immunogenicity><immunoresponse><improved><innovate><innovation><innovative><life span><lifespan><lipid based nanoparticle><lipid nanoparticle><lymph gland><lymph node biopsy><lymph nodes><lymphnodes><mRNA><mRNA Translation><mRNA lipid nano particle vaccine><mRNA vaccine><mRNA-LNP based vaccine><mRNA-LNP combination vaccines><mRNA-LNP vaccines><mRNA-based vaccine><miRNA><mouse model><murine model><nCoV vaccine><nCoV-19 vaccine><nCoV19 vaccine><nCoV2><next generation><non-human primate><nonhuman primate><novel><older adult><older adulthood><older groups><older individuals><older person><pandemic virus><pathway><peripheral blood><phase 1 study><phase I protocol><plasmocyte><population aging><primary outcome><randomisation><randomization><randomly assigned><research clinical testing><respiratory><response><safety assessment><safety testing><spike proteins on SARS-CoV-2><transcriptional silencing><transcriptomics><translation><unpublished works><vaccination strategy><vaccine against 2019-nCov><vaccine against COVID-19><vaccine against SARS-CoV-2><vaccine against SARS-coronavirus-2><vaccine against Severe Acute Respiratory Syndrome CoV 2><vaccine against Severe acute respiratory syndrome coronavirus 2><vaccine candidate><vaccine candidates against SARS-CoV-2><vaccine for novel coronavirus><vaccine strategy><vaccines preventing COVID><vaccines to prevent COVID><viral infection><virus infection><virus-induced disease><young adult><young adult age><young adulthood>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HIDEKAZU TSUKAMOTO

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,666,183
FY 2025

Project Title

Southern California Research Center for ALPD and Cirrhosis

Grant Number:

5P50AA011999-27

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/31/1998

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL - SUMMARY Alcohol-associated liver and pancreatic diseases (ALPD) and cirrhosis constitute leading metabolic diseases caused by alcohol use disorder around the globe. The Southern California Research Center for ALPD and Cirrhosis unifies 60 investigators from six academic institutions in Sou...

Research Terms

<Alcohol Chemical Class><Alcohol Drinking><Alcohol associated hepatitis><Alcohol consumption><Alcohol hepatitis><Alcohol induced hepatitis><Alcohol related hepatitis><Alcoholic Hepatitis><Alcoholic Liver Diseases><Alcohols><Animal Model><Animal Models and Related Studies><Animals><Antioncogene Protein p53><Automobile Driving><Award><Bacteriophages><Basic Research><Basic Science><CTLA-8><CTLA-8 Gene><CTLA8><CTLA8 Gene><California><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cell Body><Cells><Cellular Tumor Antigen P53><Cholesterol><Cicatrix><Cirrhosis><Clinical Research><Clinical Study><Clinical Treatment Moab><Collaborations><Communities><Cytolysins><Cytotoxic T-Lymphocyte-Associated Antigen 8><Cytotoxic T-Lymphocyte-Associated Antigen 8 Gene><Cytotoxic T-Lymphocyte-Associated Serine Esterase 8><Cytotoxic T-Lymphocyte-Associated Serine Esterase 8 Gene><Development><Disease><Disorder><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><E faecalis><E. faecalis><Early-Stage Clinical Trials><Education><Education and Training><Educational aspects><Educational process of instructing><Educational workshop><Enterococcus faecalis><Environment><EtOH drinking><EtOH use><Ethanol-induced hepatitis><Event><Faculty><Feasibility Studies><Fellowship><Fostering><Funding><Future Generations><Gene Transcription><Generalized Growth><Generations><Genetic Transcription><Goals><Grant><Growth><Health Care Providers><Health Personnel><Hepatic Cancer><Hepatic Disorder><Hepatic Neoplasms><Hepatitis><Home><IL-17><IL-17 Gene><IL-17A><IL-17A Gene><IL-23><IL17><IL17 Protein><IL17 gene><IL17A><IL17A Gene><Inflammation><Infrastructure><Institution><Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8)><Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8) Gene><Interleukin 17 Precursor><Interleukin 17 Precursor Gene><Interleukin-17><International><Investigators><Investments><K-Awards><K-Series Research Career Programs><Life Style><Lifestyle><Liver><Liver diseases><Liver neoplasms><Logistics><MD students><Malignant neoplasm of liver><Medical><Medical Students><Mentors><Metabolic><Metabolic Diseases><Metabolic Disorder><Mission><Modality><Modeling><Molecular><Monoclonal Antibodies><Morbidity><Morbidity - disease rate><NIAAA><NIH><National Institute on Alcohol Abuse and Alcoholism><National Institutes of Health><Nature><Oncogene Products><Oncogene Proteins><Oncoprotein p53><Oncoproteins><Outcome><P53><Pancreas><Pancreatic><Pancreatic Diseases><Pancreatic Disorder><Pancreatitis><Patients><Phages><Phase 1 Clinical Trials><Phase I Clinical Trials><Phosphoprotein P53><Phosphoprotein pp53><Pilot Projects><Placebo Control><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Preventive><Protein TP53><Publications><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Expression><Randomized><Recurrence><Recurrent><Reporting><Research><Research Associate><Research Career Program><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Specimen><Research Training><Researchers><Resources><S faecalis><S. faecalis><Scars><Science><Scientific Publication><Scientist><Seminal><Service delivery model><Service model><Services><Simvastatin><Specimen><Stem Cell like><Streptococcus Group D><Streptococcus faecalis><Students><Synvinolin><TP53><TP53 gene><TRP53><Teaching><Technology><Therapeutic><Thesaurismosis><Tissue Growth><Training><Training and Education><Transcription><Translational Research><Translational Science><Trypsinogen><Tumor Protein p53><Tumor Protein p53 Gene><United States National Institutes of Health><Universities><Virus><Workshop><acute pancreatitis><alcohol consequences><alcohol induced hepatic injury><alcohol induced liver disorder><alcohol induced liver injury><alcohol ingestion><alcohol intake><alcohol product use><alcohol related consequences><alcohol related liver disease><alcohol use><alcohol use disorder><alcohol-associated liver disease><alcohol-induced hepatic dysfunction><alcohol-induced liver disease><alcohol-induced liver dysfunction><alcohol-mediated liver dysfunction><alcohol-mediated liver injury><alcohol-related liver disease><alcoholic beverage consumption><alcoholic drink intake><alcoholic liver injury><bacteria in the gut><bacterial virus><base><bases><care delivery model><career><career development><cirrhotic><clinical relevance><clinically relevant><community center><community centers><conference><convention><depository><developmental><drinking behavior><driving><ethanol consumption><ethanol drinking><ethanol induced hepatic injury><ethanol induced liver disorder><ethanol induced liver injury><ethanol ingestion><ethanol intake><ethanol liver disease><ethanol product use><ethanol use><ethanol use disorder><ethanol-induced hepatic dysfunction><ethanol-induced liver disease><ethanol-induced liver dysfunction><ethanol-mediated liver dysfunction><ethanol-mediated liver injury><graduate student><gut bacteria><health care delivery model><health care personnel><health care worker><health provider><health workforce><hepatic body system><hepatic disease><hepatic neoplasia><hepatic neoplasm><hepatic organ system><hepatic tumor><hepatopathy><homes><humanized mice><humanized mouse><improved><innovate><innovation><innovative><insight><interleukin-23><liver cancer><liver disorder><liver malignancy><liver tumor><mAbs><malignant liver tumor><medical personnel><medical school students><member><metabolism disorder><microbial consortia><microbial flora><microbiota><microflora><model of animal><monoclonal Abs><mortality><mouse model><multidisciplinary><multispecies consortia><murine model><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><ontogeny><outreach><p53 Antigen><p53 Genes><p53 Tumor Suppressor><pancreas disorder><phase 1 trial><phase I protocol><phase I trial><pilot study><placebo controlled><post-doc><post-doctoral><post-doctoral trainee><pre-clinical><preclinical><premature><prematurity><progenitor capacity><progenitor cell like><progenitor-like><programs><protein p53><randomisation><randomization><randomly assigned><repository><research associates><self-renew><self-renewal><stem cell characteristics><stem-like><stemness><summer research><summit><symposia><symposium><therapeutic agent development><therapeutic development><therapeutic target><translation research><translational investigation><translational study><treatment provider><trial planning><tumor initiation><undergrad><undergraduate><undergraduate student>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HANSELL H STEDMAN

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,620,242
FY 2025

Project Title

IND-enabling studies of non-immunogenic gene therapy for ultra-rare DMD patients excluded from dystrophin trials

Grant Number:

5U01NS134672-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2024

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Duchenne muscular dystrophy (DMD) is a rare childhood onset neuromuscular disease caused by genetic deficiency of the protein dystrophin. DMD is an incurable disease with a devastating impact on patients as a result of progressive weakness, wheelchair confinement, loss of independence/activities of ...

Research Terms

<AAV vector><AAV-based vector><Accelerometer><Activities of Daily Living><Activities of everyday life><Address><Adeno-Associated Viruses><Age><Alternative Therapies><Alternative intervention><Animal Model><Animal Models and Related Studies><Animals><Antigenic Determinants><Assay><Becker Muscular Dystrophinopathies><Becker Muscular Dystrophy><Becker dystrophy><Becker pseudohypertrophic muscular dystrophy><Becker type progressive muscular dystrophy><Becker-Kiener muscular dystrophy><Binding Determinants><Bioassay><Biochemical><Biodistribution><Biological Assay><Biological Markers><Blinded><Cessation of life><Childhood><Clinical><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Complex><Cyclic GMP><Cytoskeletal Gene><Cytoskeletal Proteins><DNA Therapy><DNA mutation><Data><Death><Dependoparvovirus><Dependovirus><Development><Diagnosis><Disease><Disorder><Dose><Duchene><Duchenne><Duchenne muscular dystrophy><Duchenne-Griesinger syndrome><Duchenne/Becker muscular dystrophy><Dysfunction><Dystrophin><Dystrophin-Related Protein><Dystrophin-Related Protein 1><ELISA><Ellis-van Creveld (EvC) syndrome><Enrollment><Ensure><Enzyme-Linked Immunosorbent Assay><Epitopes><Exclusion><Exons><FDA approved><Feedback><Functional disorder><Gene Alteration><Gene Mutation><Gene Therapy Vectors><Gene Transduction Agent><Gene Transduction Vectors><Gene Transfer Clinical><Gene therapy trial><Genes><Genetic><Genetic Change><Genetic Diseases><Genetic Intervention><Genetic Risk><Genetic defect><Genetic mutation><German><German population><Glycoproteins><Guanosine Cyclic Monophosphate><Hair><Human><IND Filing><IND application><IND package><IND submission><IRB><IRBs><Immune Evasion><Immune Tolerance><Immunologic Tolerance><Incidence><Injury><Institutional Review Boards><Investigational New Drug Application><Investigators><Isoforms><Length><Link><Measurable><Measurement><Mediating><Medicine><Membrane><Mission><Modern Man><Muscle><Muscle Cell Contraction><Muscle Cells><Muscle Contraction><Muscle Disease><Muscle Disorders><Muscle Tissue><Muscular Contraction><Muscular Diseases><Muscular Dystrophies><Mutation><Myocytes><Myodystrophica><Myodystrophy><Myopathic Conditions><Myopathic Diseases and Syndromes><Myopathic disease or syndrome><Myopathy><N-terminal><NH2-terminal><NINDS><National Institute of Neurological Diseases and Stroke><National Institute of Neurological Disorders and Stroke><Nature><Neuromuscular Diseases><Other Genetics><Outcome Measure><Patients><Peptides><Performance><Phase><Physical activity><Physiologic><Physiological><Physiopathology><Pre IND FDA meeting><Pre-Clinical Model><Pre-IND mtg><Preclinical Models><Prediction of Response to Therapy><Preparation><Probability><Process><Protein Isoforms><Proteins><Pseudohypertrophic Muscular Dystrophy><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><Recombinant Proteins><Regulation><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Subjects><Researchers><Risk><Rod><Safety><Serious Adverse Event><Severe Adverse Event><Site><Spectrin><Structure><T cell response><T-Cells><T-Lymphocyte><Technology Transfer><Testing><Therapeutic><Thymus><Thymus Gland><Thymus Proper><Thymus Reticuloendothelial System><Time><Toxicology><Transgenes><Translational Research><Translational Science><Transmission><Treatment Efficacy><UTRN Protein><Urine><Utrophin><Validation><Wheel Chairs><Wheelchairs><Writing><X-linked dilated cardiomyopathy><X-linked muscular dystrophy><X-linked recessive muscular dystrophy><absorption><accelerometry><activity monitor><activity tracker><adeno associated virus group><adeno-associated viral vector><adeno-associated virus vector><ages><benign X-linked recessive muscular dystrophy><bio-markers><biologic marker><biomarker><biomarker performance><biomarker utility><cGMP><canine animal model><canine model><childhood pseudohypertrophic muscular dystrophy><classic X-linked recessive muscular dystrophy><clinical investigation><connectin><daily living function><daily living functionality><design><designing><determine efficacy><developmental><dog model><early childhood><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy study><enroll><enzyme linked immunoassay><evaluate efficacy><examine efficacy><experiment><experimental research><experimental study><experiments><functional ability><functional capacity><gene defect><gene repair therapy><gene therapy><gene therapy clinical study><gene transfer trial><gene-based therapy><genetic condition><genetic disorder><genetic therapy><genome mutation><genomic therapy><immune evasive><immune system tolerance><immune unresponsiveness><immunogenic><immunological paralysis><in vivo><injuries><innovate><innovation><innovative><intervention efficacy><male><manufacture><mdx mouse><measurable outcome><membrane structure><micro-dystrophin><microdystrophin><mild X-linked recessive muscular dystrophy><miniaturize><miniaturized><model of animal><multidisciplinary><muscle dystrophy><muscular><muscular disorder><mutant allele><myoneural disorder><neuromuscular degenerative disorder><neuromuscular disorder><novel><outcome measurement><pathophysiology><patient population><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><pediatric><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><pre-clinical><pre-clinical study><preclinical><preclinical study><predict therapeutic response><predict therapy response><premature><prematurity><preparations><programs><progressive muscular dystrophy of childhood><protein folding><pseudohypertrophic adult muscular dystrophy><pseudohypertrophic muscular paralysis><rare genetic disease><rare genetic disorder><response><safety study><serious adverse experience><serious adverse reaction><therapeutic agent development><therapeutic development><therapeutic efficacy><therapy efficacy><therapy prediction><thymus derived lymphocyte><titin><transgene><translation research><translational investigation><transmission process><treatment prediction><treatment response prediction><triple helix><urinary><validations><vector><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gary S Gilkeson

MEDICAL UNIVERSITY OF SOUTH CAROLINA, CHARLESTON, SC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,459,720
FY 2025

Project Title

A Phase II Controlled Trial of Allogeneic Mesenchymal Stromal Cells for the Treatment of Refractory Lupus (MiSLE)

Grant Number:

5U01AI184159-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2024

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract Cellular therapies for the treatment of autoimmune diseases offers a novel treatment option with possible increased efficacy and decreased toxicity. We are performing the first multi-center double blind placebo controlled dose escalation trial of mesenchymal stromal cells (MSCs) for standar...

Research Terms

<Active Follow-up><Address><Aliquot><Allogenic><Anti-Rejection Therapy><Area><Assay><Autoimmune Diseases><Autologous><Azathioprine><Azothioprine><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Back><Benchmarking><Benlysta><Best Practice Analysis><Bioassay><Biological Agent><Biological Assay><Biological Products><Biological Response Modifiers><Biomodulators><Blinded><Blood Plasma><CAR T cells><CAR modified T cells><CAR-T><CAR-Ts><CITE sequencing><CITE-seq><CITEseq><COVID crisis><COVID epidemic><COVID pandemic><COVID-19><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 pandemic affected><COVID-19 pandemic consequence><COVID-19 pandemic effects><COVID-19 pandemic impact><COVID-19 pandemic impacted><COVID-19 period><COVID-19 public health crisis><COVID-19 years><CV-19><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell Therapy><Cells><Cellular Immune Function><Cellular Indexing of Transcriptomes and Epitopes by Sequencing><China><Clinical><Clinical Trials><Coronavirus Infectious Disease 2019><Data><Detection><Development><Disease><Disorder><Dorsum><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drugs><Enrollment><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><FDA approved><Funding><Goals><Grant><Hand><Heterogeneity><Immune><Immune Mediators><Immune Mediators/Modulators><Immune mediated therapy><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologically Directed Therapy><Immunologics><Immunosuppressants><Immunosuppressive Agents><Immunosuppressive Therapy><Immunosuppressive drug><Immunosuppressive treatment><Immunotherapy><Immuran><Imuran><Imurel><Infrastructure><Intracellular Communication and Signaling><Laboratories><Lupus><Lupus Erythematosus Disseminatus><Mainland China><Mediating><Medication><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Methodology><Methods><Methotrexate><Methotrexate Methylaminopterin><Methotrexatum><Metotrexato><Mononuclear><Multi-center trial><Multicenter Trials><NIAID><NIH><National Institute of Allergy and Infectious Disease><National Institutes of Health><Participant><Pathogenicity><Patient Recruitments><Patients><Pharmaceutical Preparations><Phase><Placebo Control><Placebos><Plasma><Plasma Serum><Population><Randomized><Receptor Protein><Refractory><Regulatory T-Lymphocyte><Reporting><Research Specimen><Reticuloendothelial System, Serum, Plasma><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SLE><Safety><Sampling><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Sham Treatment><Signal Transduction><Signal Transduction Systems><Signaling><Specimen><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><T cells for CAR><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><Testing><Therapeutic Intervention><Therapeutic immunosuppression><Time><Toxic effect><Toxicities><Treg><Umbilical Cord><Umbilical cord structure><United States National Institutes of Health><active followup><adaptive immunity><artificial immunosuppression><autoimmune condition><autoimmune disorder><autoimmunity disease><belimumab><benchmark><biological signal transduction><biologics><biopharmaceutical><biotherapeutic agent><blind><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular indexing of transcriptomes and epitopes by single cell sequencing><cellular therapeutic><cellular therapy><chimeric antigen T cell receptor><chimeric antigen receptor (CAR) T cells><chimeric antigen receptor T><chimeric antigen receptor T cells><chimeric antigen receptor fusion protein T-cells><chimeric antigen receptor modified T cells><cohort><coronavirus disease 2019><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 pandemic consequence><coronavirus disease 2019 pandemic impact><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><coronavirus infectious disease-19><cost><determine efficacy><developmental><disseminated lupus erythematosus><drug/agent><effects following the COVID-19 pandemic><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><enroll><epigenetically><evaluate efficacy><examine efficacy><follow up><follow-up><followed up><followup><hands><immune function><immune suppressive agent><immune suppressor><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunosuppression therapy><immunosuppressive substance><immunosuppressor><impact of the SARS-CoV-2 pandemic><insight><intervention therapy><meeting><meetings><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><microbiome><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel technologies><novel therapeutics><novel therapy><open data><open label><open label study><open science><open-source data><participant recruitment><phase 1 trial><phase 2 trial><phase I trial><phase II trial><placebo control trial><placebo controlled><placebo controlled trial><predict responsiveness><predicting response><primary end point><primary endpoint><randomisation><randomization><randomly assigned><receptor><recruit><regulatory T-cells><response><response to therapy><response to treatment><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><sham therapy><single cell analysis><standard of care><statistical analysis><systemic lupus erythematosis><therapeutic response><therapy response><thymus derived lymphocyte><treatment effect><treatment group><treatment response><treatment responsiveness><trend>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DIANE L KAMEN

MEDICAL UNIVERSITY OF SOUTH CAROLINA, CHARLESTON, SC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,459,720
FY 2025

Project Title

A Phase II Controlled Trial of Allogeneic Mesenchymal Stromal Cells for the Treatment of Refractory Lupus (MiSLE)

Grant Number:

5U01AI184159-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2024

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract Cellular therapies for the treatment of autoimmune diseases offers a novel treatment option with possible increased efficacy and decreased toxicity. We are performing the first multi-center double blind placebo controlled dose escalation trial of mesenchymal stromal cells (MSCs) for standar...

Research Terms

<Active Follow-up><Address><Aliquot><Allogenic><Anti-Rejection Therapy><Area><Assay><Autoimmune Diseases><Autologous><Azathioprine><Azothioprine><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Back><Benchmarking><Benlysta><Best Practice Analysis><Bioassay><Biological Agent><Biological Assay><Biological Products><Biological Response Modifiers><Biomodulators><Blinded><Blood Plasma><CAR T cells><CAR modified T cells><CAR-T><CAR-Ts><CITE sequencing><CITE-seq><CITEseq><COVID crisis><COVID epidemic><COVID pandemic><COVID-19><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 pandemic affected><COVID-19 pandemic consequence><COVID-19 pandemic effects><COVID-19 pandemic impact><COVID-19 pandemic impacted><COVID-19 period><COVID-19 public health crisis><COVID-19 years><CV-19><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell Therapy><Cells><Cellular Immune Function><Cellular Indexing of Transcriptomes and Epitopes by Sequencing><China><Clinical><Clinical Trials><Coronavirus Infectious Disease 2019><Data><Detection><Development><Disease><Disorder><Dorsum><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drugs><Enrollment><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><FDA approved><Funding><Goals><Grant><Hand><Heterogeneity><Immune><Immune Mediators><Immune Mediators/Modulators><Immune mediated therapy><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologically Directed Therapy><Immunologics><Immunosuppressants><Immunosuppressive Agents><Immunosuppressive Therapy><Immunosuppressive drug><Immunosuppressive treatment><Immunotherapy><Immuran><Imuran><Imurel><Infrastructure><Intracellular Communication and Signaling><Laboratories><Lupus><Lupus Erythematosus Disseminatus><Mainland China><Mediating><Medication><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Methodology><Methods><Methotrexate><Methotrexate Methylaminopterin><Methotrexatum><Metotrexato><Mononuclear><Multi-center trial><Multicenter Trials><NIAID><NIH><National Institute of Allergy and Infectious Disease><National Institutes of Health><Participant><Pathogenicity><Patient Recruitments><Patients><Pharmaceutical Preparations><Phase><Placebo Control><Placebos><Plasma><Plasma Serum><Population><Randomized><Receptor Protein><Refractory><Regulatory T-Lymphocyte><Reporting><Research Specimen><Reticuloendothelial System, Serum, Plasma><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SLE><Safety><Sampling><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Sham Treatment><Signal Transduction><Signal Transduction Systems><Signaling><Specimen><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><T cells for CAR><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><Testing><Therapeutic Intervention><Therapeutic immunosuppression><Time><Toxic effect><Toxicities><Treg><Umbilical Cord><Umbilical cord structure><United States National Institutes of Health><active followup><adaptive immunity><artificial immunosuppression><autoimmune condition><autoimmune disorder><autoimmunity disease><belimumab><benchmark><biological signal transduction><biologics><biopharmaceutical><biotherapeutic agent><blind><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular indexing of transcriptomes and epitopes by single cell sequencing><cellular therapeutic><cellular therapy><chimeric antigen T cell receptor><chimeric antigen receptor (CAR) T cells><chimeric antigen receptor T><chimeric antigen receptor T cells><chimeric antigen receptor fusion protein T-cells><chimeric antigen receptor modified T cells><cohort><coronavirus disease 2019><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 pandemic consequence><coronavirus disease 2019 pandemic impact><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><coronavirus infectious disease-19><cost><determine efficacy><developmental><disseminated lupus erythematosus><drug/agent><effects following the COVID-19 pandemic><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><enroll><epigenetically><evaluate efficacy><examine efficacy><follow up><follow-up><followed up><followup><hands><immune function><immune suppressive agent><immune suppressor><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunosuppression therapy><immunosuppressive substance><immunosuppressor><impact of the SARS-CoV-2 pandemic><insight><intervention therapy><meeting><meetings><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><microbiome><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel technologies><novel therapeutics><novel therapy><open data><open label><open label study><open science><open-source data><participant recruitment><phase 1 trial><phase 2 trial><phase I trial><phase II trial><placebo control trial><placebo controlled><placebo controlled trial><predict responsiveness><predicting response><primary end point><primary endpoint><randomisation><randomization><randomly assigned><receptor><recruit><regulatory T-cells><response><response to therapy><response to treatment><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><sham therapy><single cell analysis><standard of care><statistical analysis><systemic lupus erythematosis><therapeutic response><therapy response><thymus derived lymphocyte><treatment effect><treatment group><treatment response><treatment responsiveness><trend>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Benjamin Lebwohl

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,400,000
FY 2025

Project Title

Evaluation of Novel Technologies to Improve Clinical Management of Celiac Disease: The GLUTECH Trial

Grant Number:

5U01DK136523-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY The proposed project addresses the need for a rigorous trial to test the effectiveness of novel gluten detection technologies as an adjunct to telemedicine to manage celiac disease in adults. Celiac disease affects about 1% of the United States (U.S.) population and seroprevalence ha...

Research Terms

<21+ years old><7S Gamma Globulin><Active Follow-up><Address><Adherence><Adoption><Adult><Adult Human><Affect><Anemia><Anti-TG2><Anti-tTG><Antibodies><Antibodies to tissue transglutaminase><Antitissue transglutaminase antibodies><Anxiety><Autoantibodies><Autoantibodies to tissue transglutaminase><Awareness><Behavioral><Blood Serum><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 antigen><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Cancers><Cannot achieve a pregnancy><Celiac Disease><Celiac Sprue><Chemistry><Clinical><Clinical Management><Clinical Trials><Coeliac Disease><Communication><Complement><Complement Proteins><Consumption><Country><Detection><Diagnosis><Dietary quality><Dietitian><Difficulty conceiving><Digestive Diseases><Digestive System Diseases><Digestive System Disorders><Disease Management><Disorder Management><Eating Behavior><Effectiveness><Evaluation><Fatigue><Food><GI tract disorder><Gastroenterology><Gliadin><Glutelin><Gluten><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Gluten-free diet><Grant><Health><Health Care Professional><Health Professional><Height><Histology><Home><IgA><IgG><Illinois><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunoglobulin A><Immunoglobulin G><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Incidence><Individual><Infertility><Infrastructure><Intervention><Lack of Energy><Link><Lymphocyte Count><Lymphocyte Number><Malignant Neoplasms><Malignant Tumor><Massachusetts><Measures><Mediator><Mental Depression><Monitor><Morbidity><Morbidity - disease rate><Motivation><Mucosa><Mucosal Tissue><Mucous Membrane><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><New York><Newly Diagnosed><Non-tropical Sprue><Nontropical Sprue><Osteoporosis><Outcome><Outcome Study><Participant><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peptide antibodies><Peptides><Performance><Persons><Physicians><Pisum sativum><Population><QOL><Quality of life><Randomized><Randomized, Controlled Trials><Recommendation><Recovery><Regimen><SARS-CoV-2 antigen><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Sample Size><Sampling><Serology><Seroprevalences><Serum><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social support><Symptoms><Technology><Telemedicine><Tennessee><Testing><Tissue Transglutaminase Antibodies><Tissue transglutaminase IgA><Tissue transglutaminase autoantibodies><Total Lymphocyte Count><Translating><United States><Urine><Videoconferencing><Villus><acceptability and feasibility><active followup><adulthood><antigen based test><antigen test><assess effectiveness><autoimmune antibody><autoreactive antibody><clinical development><comparative cost effectiveness><compare cost><compare cost effectiveness><complementation><coronavirus disease 2019 antigen><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost comparison><cost effective><cost effectiveness><deamidation><depression><determine effectiveness><diet adherence><diet quality><dietary><dietary adherence><digestive disorder><digestive tract disease><effectiveness assessment><effectiveness evaluation><effectiveness testing><evaluate effectiveness><examine effectiveness><fertility cessation><fertility loss><follow up><follow-up><followed up><followup><gastrointestinal symptom><gastrointestinal tract disease><gastrointestinal tract disorder><homes><idiopathic steatorrhea><immunogenic><improved><infertile><intraepithelial><malignancy><meeting><meetings><mortality><neoplasm/cancer><new technology><novel><novel technologies><pandemic><pandemic disease><pathway><patient oriented outcomes><pea><portability><primary end point><primary endpoint><primary outcome><psychologic><psychological><randomisation><randomization><randomized control trial><randomly assigned><rapid testing><recruit><secondary outcome><self reactive antibody><sensor><severe acute respiratory syndrome coronavirus 2 antigen><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social><social support network><standard of care><tool><validation studies><video conferencing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Randi L. Wolf

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,400,000
FY 2025

Project Title

Evaluation of Novel Technologies to Improve Clinical Management of Celiac Disease: The GLUTECH Trial

Grant Number:

5U01DK136523-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY The proposed project addresses the need for a rigorous trial to test the effectiveness of novel gluten detection technologies as an adjunct to telemedicine to manage celiac disease in adults. Celiac disease affects about 1% of the United States (U.S.) population and seroprevalence ha...

Research Terms

<21+ years old><7S Gamma Globulin><Active Follow-up><Address><Adherence><Adoption><Adult><Adult Human><Affect><Anemia><Anti-TG2><Anti-tTG><Antibodies><Antibodies to tissue transglutaminase><Antitissue transglutaminase antibodies><Anxiety><Autoantibodies><Autoantibodies to tissue transglutaminase><Awareness><Behavioral><Blood Serum><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 antigen><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Cancers><Cannot achieve a pregnancy><Celiac Disease><Celiac Sprue><Chemistry><Clinical><Clinical Management><Clinical Trials><Coeliac Disease><Communication><Complement><Complement Proteins><Consumption><Country><Detection><Diagnosis><Dietary quality><Dietitian><Difficulty conceiving><Digestive Diseases><Digestive System Diseases><Digestive System Disorders><Disease Management><Disorder Management><Eating Behavior><Effectiveness><Evaluation><Fatigue><Food><GI tract disorder><Gastroenterology><Gliadin><Glutelin><Gluten><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Gluten-free diet><Grant><Health><Health Care Professional><Health Professional><Height><Histology><Home><IgA><IgG><Illinois><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunoglobulin A><Immunoglobulin G><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Incidence><Individual><Infertility><Infrastructure><Intervention><Lack of Energy><Link><Lymphocyte Count><Lymphocyte Number><Malignant Neoplasms><Malignant Tumor><Massachusetts><Measures><Mediator><Mental Depression><Monitor><Morbidity><Morbidity - disease rate><Motivation><Mucosa><Mucosal Tissue><Mucous Membrane><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><New York><Newly Diagnosed><Non-tropical Sprue><Nontropical Sprue><Osteoporosis><Outcome><Outcome Study><Participant><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peptide antibodies><Peptides><Performance><Persons><Physicians><Pisum sativum><Population><QOL><Quality of life><Randomized><Randomized, Controlled Trials><Recommendation><Recovery><Regimen><SARS-CoV-2 antigen><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Sample Size><Sampling><Serology><Seroprevalences><Serum><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social support><Symptoms><Technology><Telemedicine><Tennessee><Testing><Tissue Transglutaminase Antibodies><Tissue transglutaminase IgA><Tissue transglutaminase autoantibodies><Total Lymphocyte Count><Translating><United States><Urine><Videoconferencing><Villus><acceptability and feasibility><active followup><adulthood><antigen based test><antigen test><assess effectiveness><autoimmune antibody><autoreactive antibody><clinical development><comparative cost effectiveness><compare cost><compare cost effectiveness><complementation><coronavirus disease 2019 antigen><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost comparison><cost effective><cost effectiveness><deamidation><depression><determine effectiveness><diet adherence><diet quality><dietary><dietary adherence><digestive disorder><digestive tract disease><effectiveness assessment><effectiveness evaluation><effectiveness testing><evaluate effectiveness><examine effectiveness><fertility cessation><fertility loss><follow up><follow-up><followed up><followup><gastrointestinal symptom><gastrointestinal tract disease><gastrointestinal tract disorder><homes><idiopathic steatorrhea><immunogenic><improved><infertile><intraepithelial><malignancy><meeting><meetings><mortality><neoplasm/cancer><new technology><novel><novel technologies><pandemic><pandemic disease><pathway><patient oriented outcomes><pea><portability><primary end point><primary endpoint><primary outcome><psychologic><psychological><randomisation><randomization><randomized control trial><randomly assigned><rapid testing><recruit><secondary outcome><self reactive antibody><sensor><severe acute respiratory syndrome coronavirus 2 antigen><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social><social support network><standard of care><tool><validation studies><video conferencing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ITZHAK FRIED

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,338,427
FY 2025

Project Title

Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles

Grant Number:

5U01NS123128-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT Episodic memories integrate the content of human experience in space and time and constitute the core of one's identity. Memory formation involves processing, and constructing interpretations of the incoming information in our daily lives and is one of the first functions co...

Research Terms

<AD dementia><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Acoustic Stimulation><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Ammon Horn><Animals><Area><Artificial Intelligence enhanced><Auditory><Auditory Cortex><Auditory Stimulation><Auditory area><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavior><Brain><Brain Nervous System><Brain region><Cell Body><Cells><Clinical><Code><Coding System><Cognitive><Cognitive Retention Disorders><Cornu Ammonis><Coupling><Data><Degenerative Neurologic Disorders><Delta Wave><Delta Wave sleep><Development><E-stim><Electric Stimulation><Electrodes><Electrophysiology><Electrophysiology (science)><Encephalon><Episodic memory><Event><Face><Foundations><Future><General Population><General Public><Goals><Hippocampus><Human><Intervention><Knowledge><Life><Maps><Measures><Memory><Memory Deficit><Memory Disorders><Memory impairment><Methodology><Modeling><Modern Man><Nature><Nerve Cells><Nerve Unit><Nervous System Degenerative Diseases><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurologic Disorders><Neurological Disorders><Neurons><Neurophysiology / Electrophysiology><Neurosciences><Participant><Patient Monitoring><Pattern><Performance><Personal Satisfaction><Persons><Physiologic><Physiologic pulse><Physiological><Physiology><Play><Prevalence><Primary Senile Degenerative Dementia><Probability><Process><Protocol><Protocols documentation><Pulse><Research><Resolution><Response to stimulus physiology><Retrieval><Rodent><Rodentia><Rodents Mammals><Sample Size><Sampling><Scheme><Series><Site><Sleep><Sleep Architecture><Slow-Wave Sleep><Stimulus><System><Techniques><Technology><Testing><Therapeutic><Therapeutic Intervention><Time><Tsunami><Wakefulness><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><awake><computer based prediction><deep learning><deep learning algorithm><deep learning based model><deep learning method><deep learning model><deep learning strategy><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><developmental><electrophysiological><electrostimulation><enhanced with AI><enhanced with Artificial Intelligence><experience><faces><facial><high dimensional data><hippocampal><improved><innovate><innovation><innovative><interdisciplinary approach><interdisciplinary collaboration><intervention therapy><medial temporal area><medial temporal lobe><memory consolidation><memory dysfunction><memory process><memory processing><memory recognition><memory retrieval><mesial temporal area><mesial temporal lobe><movie><multi-modality><multidimensional data><multidimensional datasets><multidisciplinary><multidisciplinary approach><multimodality><neural><neural mechanism><neural patterning><neurodegenerative illness><neurological disease><neuromechanism><neuronal><neurosurgery><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><population aging><predictive modeling><primary degenerative dementia><recruit><resolutions><senile dementia of the Alzheimer type><sleep behavior><sleep habit><sleep/wake behavior><spatial and temporal><spatial temporal><spatiotemporal><stimulus/response><substantia alba><tool><transdisciplinary collaboration><well-being><wellbeing><white matter>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sameer Anil Sheth

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,311,144
FY 2025

Project Title

Mapping Algorithmic State Space in the Human Brain

Grant Number:

5U01NS121472-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2021

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract Humans have a remarkable ability to flexibly interact with the environment. A compelling demonstration of this cognitive flexibility is our ability to respond correctly to novel contextual situations on the first attempt, without prior rehearsal. We refer to this ability as ‘ad hoc self-pro...

Research Terms

<AI system><Acute><Address><Algorithms><Amaze><Ammon Horn><Anterior><Artificial Intelligence><Behavior><Behavioral><Brain><Brain Nervous System><Causality><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic><Cinnamon><Cinnamon - dietary><Cognitive><Complex><Computer Models><Computer Reasoning><Computerized Models><Cornu Ammonis><Data><Development><Devices><Elements><Encephalon><Engineering><Entorhinal Area><Environment><Etiology><Frequencies><Functional MRI><Functional Magnetic Resonance Imaging><Goals><Hippocampus><Human><Implant><Individual><Inpatients><Instruction><Intelligence><Intracellular Communication and Signaling><Link><Location><Machine Intelligence><Maps><Medial><Modeling><Modern Man><Monitor><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurosciences><Neurosciences Research><Participant><Pattern><Population><Prefrontal Cortex><Property><Psyche structure><Reporting><Research><Rodent><Rodentia><Rodents Mammals><Role><Series><Signal Transduction><Signal Transduction Systems><Signaling><Structure><Task Performances><Telemetries><Telemetry><Testing><Time><Variant><Variation><Work><biological signal transduction><causation><cell cortex><cognitive neuroscience><cohort><computational basis><computational modeling><computational models><computer based models><computer based prediction><computerized modeling><design><designing><developmental><disease causation><entorhinal cortex><epilepsy participant><epilepsy patient><epilepsy subject><epilepsy volunteer><epileptic patient><epileptic subject><experience><fMRI><flexibility><flexible><hippocampal><immersive digital environment><immersive environment><immersive virtual environment><immersive virtual reality><innovate><innovation><innovative><medial temporal area><medial temporal lobe><mental><mental representation><mesial temporal area><mesial temporal lobe><neural><neuronal><neuronal circuit><neuronal circuitry><neurophysiological><neurophysiology><neurosurgery><novel><operation><operations><patients with epilepsy><physical state><predictive modeling><programs><rehearsal><response><social role><spatial navigation><telemetric><virtual reality><virtual reality environment><way finding><wayfinding>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JAIMIE M HENDERSON

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,192,902
FY 2025

Project Title

Cortical basis of complex motor sequences in humans for neural interfaces

Grant Number:

5U01NS123101-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/22/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY Intracortical brain-computer interfaces (iBCIs) can restore lost function for people with severe speech and motor impairment (SSMI) due to neurological injury or disease. Despite tremendous recent progress, iBCI performance remains well below that of able-bodied people. In prior NIH-...

Research Terms

<Algorithms><Animals><Area><Arm Prosthesis><Artificial Arm><Bilateral><Body part><Brain><Brain Hemisphere><Brain Nervous System><Cell Communication and Signaling><Cell Phone><Cell Signaling><Cellular Phone><Cellular Telephone><Cerebral hemisphere><Chronic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Code><Coding System><Communication><Complex><Computers><Creativeness><Data><Devices><Dimensions><Educational process of instructing><Encephalon><Enrollment><Esthesia><Extremities><Face><Generations><Goals><Hand><Handwriting><Head><Health Care><Health Care Providers><Health Personnel><Human><Implant><Individual><Institution><Intracellular Communication and Signaling><Investigation><Knowledge><Leg><Length><Limb structure><Limbs><Link><Medial><Mental Processes><Methods><Mobile Phones><Modern Man><Motion><Motor><Motor Cortex><Movement><Muscle><Muscle Tissue><NIH><National Institutes of Health><Nerve Cells><Nerve Unit><Nervous System Diseases><Nervous System Disorder><Nervous System Injuries><Nervous System Trauma><Nervous System damage><Neural Cell><Neurocyte><Neurologic Disorders><Neurological Damage><Neurological Disorders><Neurological Injury><Neurological trauma><Neurons><Neurosciences><Non-Trunk><Palsy><Paralysed><Performance><Persons><Plegia><Population><Precentral gyrus><Prosthesis><Prosthetic device><Prosthetics><Quadriplegia><Quadriplegic><Recreation><Reporting><Research Support><Resolution><Safety><Seminal><Sensation><Signal Transduction><Signal Transduction Systems><Signaling><Site><Social Interaction><Speech><Speed><System><Teaching><Technology><Tetraplegia><Text><Time><Translating><United States National Institutes of Health><Utah><Work><Writing><arm><arm movement><base><bases><biological signal transduction><body map><body movement><brain computer interface><creativity><design><designing><enroll><exoskeletal><exoskeleton><experience><faces><facial><functional restoration><hands><health care personnel><health care worker><health provider><health workforce><iPhone><loved ones><marginalization><medical personnel><motor impairment><movement impairment><movement limitation><muscular><neural><neural mechanism><neuroethics><neurological disease><neuromechanism><neuronal><neurophysiological><neurophysiology><neurotrauma><next generation><non-human primate><nonhuman primate><novel><paralysis><paralytic><pre-clinical research><preclinical research><prosthetic arm><resolutions><restoration><restore function><restore functionality><restore lost function><safety assessment><smart phone><smartphone><tetraplegic><treatment provider><virtual reality>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nicholette D. Allred

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,177,380
FY 2025

Project Title

14/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Scientific Data Research Center

Grant Number:

5U01DK116041-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The NIH APOL1 Long-term Transplantation Outcomes Network (APOLLO) Collaborative U01 is performing a national prospective evaluation of donor and recipient apolipoprotein L1 gene (APOL1) risk variants in US kidney transplants from African American donors to determine their effect on transplant outcom...

Research Terms

<21+ years old><APOL-I><APOL1><APOL1 gene><Acute><Adult><Adult Human><African American><African American group><African American individual><African American people><African American population><African Americans><African ancestry><African descent><Afro American><Afroamerican><Allografting><American><Ancillary Study><Apolipoproteins><Archives><Bioinformatics><Biometrics><Biometry><Biostatistics><Blood Serum><Childhood><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Cohort Studies><Collection><Communities><Concurrent Studies><Creatinine><DNA><Data><Data Analyses><Data Analysis><Data Bases><Databases><Decision Making><Deoxyribonucleic Acid><Development><Disparities><Disparity><Eligibility><Eligibility Determination><Engraftment><Enrollment><Ensure><Ethicists><Ethics><Ethics Consultants><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><European><Evaluation><Failure><Genes><Genetic><Genotype><Glomerular Filtration Rate><Graft Survival><Health><Health Care Costs><Health Costs><Health protection><Hemoglobin S><Histology><Human Resources><IRB><IRBs><Individual><Informed Consent><Institutional Review Boards><Investigators><Kidney><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Laboratories><Leadership><Link><Manpower><Manuals><Monitor><Multi-center studies><Multicenter Studies><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nephrology><Observation research><Observation study><Observational Study><Observational research><Operative Procedures><Operative Surgical Procedures><Organ><Organ Procurements><Outcome><Outcome Assessment><Participant><Patients><Physicians><Population><Predisposition><Procedures><Process><Prospective Studies><Proteinuria><Protocol><Protocol Screening><Protocols documentation><Publications><QOL improvement><Racial Group><Renal Grafting><Renal Transplantation><Renal Transplants><Renal function><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Retrospective Studies><Risk><Risk-associated variant><Safety><Sampling><Scientific Publication><Serum><Sickle Hemoglobin><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Structure><Surgical><Surgical Interventions><Surgical Procedure><Susceptibility><Time><Transplant Recipients><Transplantation><UNOS><United Network for Organ Sharing><United States National Institutes of Health><Universities><Variant><Variation><Viral Diseases><Virus Diseases><Vital Status><Work><adulthood><biobank><biorepository><chronic kidney disease><clinical center><data base><data interpretation><data quality><deceased donor><deceased organ donors><depository><design><designing><developmental><disparity in ethnic><donor antibodies><donor-specific antibody><enroll><ethical><ethnic based disparity><ethnic disadvantage><ethnic disparity><ethnic inequality><ethnic inequity><ethnic subgroup><ethnicity disparity><ethnicity group><genetic information><genome scale><genome-wide><genomewide><graft function><improved><improvements in QOL><improvements in quality of life><kidney allograft><kidney function><kidney tx><live kidney donor><living kidney donor><medical college><medical schools><organ allocation><organ procurement transplantation network><pediatric><personnel><post-transplant><post-transplantation><posthumous donors><posthumous organ donor><posttransplant><posttransplantation><precision medicine><precision-based medicine><primary outcome><programs><prospective><quality of life improvement><racial population><racial subgroup><recruit><renal><renal allograft><repository><response><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><school of medicine><skills><statistical analysis><surgery><tool><transplant><transplant patient><viral infection><virus infection><virus-induced disease><web site><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

BARRY Ira FREEDMAN

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,177,380
FY 2025

Project Title

14/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Scientific Data Research Center

Grant Number:

5U01DK116041-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The NIH APOL1 Long-term Transplantation Outcomes Network (APOLLO) Collaborative U01 is performing a national prospective evaluation of donor and recipient apolipoprotein L1 gene (APOL1) risk variants in US kidney transplants from African American donors to determine their effect on transplant outcom...

Research Terms

<21+ years old><APOL-I><APOL1><APOL1 gene><Acute><Adult><Adult Human><African American><African American group><African American individual><African American people><African American population><African Americans><African ancestry><African descent><Afro American><Afroamerican><Allografting><American><Ancillary Study><Apolipoproteins><Archives><Bioinformatics><Biometrics><Biometry><Biostatistics><Blood Serum><Childhood><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Cohort Studies><Collection><Communities><Concurrent Studies><Creatinine><DNA><Data><Data Analyses><Data Analysis><Data Bases><Databases><Decision Making><Deoxyribonucleic Acid><Development><Disparities><Disparity><Eligibility><Eligibility Determination><Engraftment><Enrollment><Ensure><Ethicists><Ethics><Ethics Consultants><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><European><Evaluation><Failure><Genes><Genetic><Genotype><Glomerular Filtration Rate><Graft Survival><Health><Health Care Costs><Health Costs><Health protection><Hemoglobin S><Histology><Human Resources><IRB><IRBs><Individual><Informed Consent><Institutional Review Boards><Investigators><Kidney><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Laboratories><Leadership><Link><Manpower><Manuals><Monitor><Multi-center studies><Multicenter Studies><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nephrology><Observation research><Observation study><Observational Study><Observational research><Operative Procedures><Operative Surgical Procedures><Organ><Organ Procurements><Outcome><Outcome Assessment><Participant><Patients><Physicians><Population><Predisposition><Procedures><Process><Prospective Studies><Proteinuria><Protocol><Protocol Screening><Protocols documentation><Publications><QOL improvement><Racial Group><Renal Grafting><Renal Transplantation><Renal Transplants><Renal function><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Retrospective Studies><Risk><Risk-associated variant><Safety><Sampling><Scientific Publication><Serum><Sickle Hemoglobin><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Structure><Surgical><Surgical Interventions><Surgical Procedure><Susceptibility><Time><Transplant Recipients><Transplantation><UNOS><United Network for Organ Sharing><United States National Institutes of Health><Universities><Variant><Variation><Viral Diseases><Virus Diseases><Vital Status><Work><adulthood><biobank><biorepository><chronic kidney disease><clinical center><data base><data interpretation><data quality><deceased donor><deceased organ donors><depository><design><designing><developmental><disparity in ethnic><donor antibodies><donor-specific antibody><enroll><ethical><ethnic based disparity><ethnic disadvantage><ethnic disparity><ethnic inequality><ethnic inequity><ethnic subgroup><ethnicity disparity><ethnicity group><genetic information><genome scale><genome-wide><genomewide><graft function><improved><improvements in QOL><improvements in quality of life><kidney allograft><kidney function><kidney tx><live kidney donor><living kidney donor><medical college><medical schools><organ allocation><organ procurement transplantation network><pediatric><personnel><post-transplant><post-transplantation><posthumous donors><posthumous organ donor><posttransplant><posttransplantation><precision medicine><precision-based medicine><primary outcome><programs><prospective><quality of life improvement><racial population><racial subgroup><recruit><renal><renal allograft><repository><response><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><school of medicine><skills><statistical analysis><surgery><tool><transplant><transplant patient><viral infection><virus infection><virus-induced disease><web site><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Carl D Langefeld

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,177,380
FY 2025

Project Title

14/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Scientific Data Research Center

Grant Number:

5U01DK116041-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The NIH APOL1 Long-term Transplantation Outcomes Network (APOLLO) Collaborative U01 is performing a national prospective evaluation of donor and recipient apolipoprotein L1 gene (APOL1) risk variants in US kidney transplants from African American donors to determine their effect on transplant outcom...

Research Terms

<21+ years old><APOL-I><APOL1><APOL1 gene><Acute><Adult><Adult Human><African American><African American group><African American individual><African American people><African American population><African Americans><African ancestry><African descent><Afro American><Afroamerican><Allografting><American><Ancillary Study><Apolipoproteins><Archives><Bioinformatics><Biometrics><Biometry><Biostatistics><Blood Serum><Childhood><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Cohort Studies><Collection><Communities><Concurrent Studies><Creatinine><DNA><Data><Data Analyses><Data Analysis><Data Bases><Databases><Decision Making><Deoxyribonucleic Acid><Development><Disparities><Disparity><Eligibility><Eligibility Determination><Engraftment><Enrollment><Ensure><Ethicists><Ethics><Ethics Consultants><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><European><Evaluation><Failure><Genes><Genetic><Genotype><Glomerular Filtration Rate><Graft Survival><Health><Health Care Costs><Health Costs><Health protection><Hemoglobin S><Histology><Human Resources><IRB><IRBs><Individual><Informed Consent><Institutional Review Boards><Investigators><Kidney><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Laboratories><Leadership><Link><Manpower><Manuals><Monitor><Multi-center studies><Multicenter Studies><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nephrology><Observation research><Observation study><Observational Study><Observational research><Operative Procedures><Operative Surgical Procedures><Organ><Organ Procurements><Outcome><Outcome Assessment><Participant><Patients><Physicians><Population><Predisposition><Procedures><Process><Prospective Studies><Proteinuria><Protocol><Protocol Screening><Protocols documentation><Publications><QOL improvement><Racial Group><Renal Grafting><Renal Transplantation><Renal Transplants><Renal function><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Retrospective Studies><Risk><Risk-associated variant><Safety><Sampling><Scientific Publication><Serum><Sickle Hemoglobin><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Structure><Surgical><Surgical Interventions><Surgical Procedure><Susceptibility><Time><Transplant Recipients><Transplantation><UNOS><United Network for Organ Sharing><United States National Institutes of Health><Universities><Variant><Variation><Viral Diseases><Virus Diseases><Vital Status><Work><adulthood><biobank><biorepository><chronic kidney disease><clinical center><data base><data interpretation><data quality><deceased donor><deceased organ donors><depository><design><designing><developmental><disparity in ethnic><donor antibodies><donor-specific antibody><enroll><ethical><ethnic based disparity><ethnic disadvantage><ethnic disparity><ethnic inequality><ethnic inequity><ethnic subgroup><ethnicity disparity><ethnicity group><genetic information><genome scale><genome-wide><genomewide><graft function><improved><improvements in QOL><improvements in quality of life><kidney allograft><kidney function><kidney tx><live kidney donor><living kidney donor><medical college><medical schools><organ allocation><organ procurement transplantation network><pediatric><personnel><post-transplant><post-transplantation><posthumous donors><posthumous organ donor><posttransplant><posttransplantation><precision medicine><precision-based medicine><primary outcome><programs><prospective><quality of life improvement><racial population><racial subgroup><recruit><renal><renal allograft><repository><response><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><school of medicine><skills><statistical analysis><surgery><tool><transplant><transplant patient><viral infection><virus infection><virus-induced disease><web site><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Robert J Stratta

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,177,380
FY 2025

Project Title

14/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Scientific Data Research Center

Grant Number:

5U01DK116041-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The NIH APOL1 Long-term Transplantation Outcomes Network (APOLLO) Collaborative U01 is performing a national prospective evaluation of donor and recipient apolipoprotein L1 gene (APOL1) risk variants in US kidney transplants from African American donors to determine their effect on transplant outcom...

Research Terms

<21+ years old><APOL-I><APOL1><APOL1 gene><Acute><Adult><Adult Human><African American><African American group><African American individual><African American people><African American population><African Americans><African ancestry><African descent><Afro American><Afroamerican><Allografting><American><Ancillary Study><Apolipoproteins><Archives><Bioinformatics><Biometrics><Biometry><Biostatistics><Blood Serum><Childhood><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Cohort Studies><Collection><Communities><Concurrent Studies><Creatinine><DNA><Data><Data Analyses><Data Analysis><Data Bases><Databases><Decision Making><Deoxyribonucleic Acid><Development><Disparities><Disparity><Eligibility><Eligibility Determination><Engraftment><Enrollment><Ensure><Ethicists><Ethics><Ethics Consultants><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><European><Evaluation><Failure><Genes><Genetic><Genotype><Glomerular Filtration Rate><Graft Survival><Health><Health Care Costs><Health Costs><Health protection><Hemoglobin S><Histology><Human Resources><IRB><IRBs><Individual><Informed Consent><Institutional Review Boards><Investigators><Kidney><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Laboratories><Leadership><Link><Manpower><Manuals><Monitor><Multi-center studies><Multicenter Studies><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nephrology><Observation research><Observation study><Observational Study><Observational research><Operative Procedures><Operative Surgical Procedures><Organ><Organ Procurements><Outcome><Outcome Assessment><Participant><Patients><Physicians><Population><Predisposition><Procedures><Process><Prospective Studies><Proteinuria><Protocol><Protocol Screening><Protocols documentation><Publications><QOL improvement><Racial Group><Renal Grafting><Renal Transplantation><Renal Transplants><Renal function><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Retrospective Studies><Risk><Risk-associated variant><Safety><Sampling><Scientific Publication><Serum><Sickle Hemoglobin><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Structure><Surgical><Surgical Interventions><Surgical Procedure><Susceptibility><Time><Transplant Recipients><Transplantation><UNOS><United Network for Organ Sharing><United States National Institutes of Health><Universities><Variant><Variation><Viral Diseases><Virus Diseases><Vital Status><Work><adulthood><biobank><biorepository><chronic kidney disease><clinical center><data base><data interpretation><data quality><deceased donor><deceased organ donors><depository><design><designing><developmental><disparity in ethnic><donor antibodies><donor-specific antibody><enroll><ethical><ethnic based disparity><ethnic disadvantage><ethnic disparity><ethnic inequality><ethnic inequity><ethnic subgroup><ethnicity disparity><ethnicity group><genetic information><genome scale><genome-wide><genomewide><graft function><improved><improvements in QOL><improvements in quality of life><kidney allograft><kidney function><kidney tx><live kidney donor><living kidney donor><medical college><medical schools><organ allocation><organ procurement transplantation network><pediatric><personnel><post-transplant><post-transplantation><posthumous donors><posthumous organ donor><posttransplant><posttransplantation><precision medicine><precision-based medicine><primary outcome><programs><prospective><quality of life improvement><racial population><racial subgroup><recruit><renal><renal allograft><repository><response><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><school of medicine><skills><statistical analysis><surgery><tool><transplant><transplant patient><viral infection><virus infection><virus-induced disease><web site><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DEBORAH A HALL

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,169,064
FY 2025

Project Title

Clinical Outcome Assessment and Treatment Monitoring Markers for Clinical Trial Readiness in FXTAS

Grant Number:

1U01NS143225-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/15/2025

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a rare, inherited, X-linked, late-onset, progressive neurodegenerative disease characterized by intention tremor, cerebellar gait ataxia, parkinsonism, and cognitive decline. Pathologically, it features brain white matter degradation, ubiquitin-...

Research Terms

<APF-1><ATP-Dependent Proteolysis Factor 1><Action Tremors><Advisory Committees><Advocate><Allopregnanolone><Antisense Agent><Antisense Oligonucleotides><Ataxia><Ataxy><Atrophic><Atrophy><Biological Markers><Brain><Brain Nervous System><Brain Stem><Brain imaging><Brainstem><CGG repeat><Care Givers><Caregivers><Cellular Stress><Cellular Stress Response><Cerebellar Gait><Cerebellar Gait Ataxias><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Consensus><Cooperative Agreements><Coordination Impairment><Cytosine><Data Bases><Databases><Degenerative Neurologic Disorders><Detection><Disease><Disorder><Disturbance in cognition><Drug Industry><Dyssynergia><Electronics><Encephalon><Enrollment><Equilibrium><Escalante syndrome><Event><FDA approved><FXTAS><Fragile X><Fragile X Syndrome><Fragile X premutation-associated tremor ataxia syndrome><Future><GABA Agonists><GABA Receptor Agonists><Gait><Gene Transcription><Genes><Genetic Transcription><Guanine><HMG-20><Hereditary><High Mobility Protein 20><Image><Impaired cognition><Inflammation><Infrastructure><Inherited><Intention Tremor><Intranuclear Inclusion Bodies><Intranuclear Inclusions><Investigators><Lead><Link><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Martin-Bell Syndrome><Martin-Bell-Renpenning syndrome><Measurement><Measures><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Messenger RNA><Mitochondria><Modification><Molecular><Monitor><Motor><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><NF-E2 protein><NF-E2 transcription factor><NFE2 protein><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Nervous System Degenerative Diseases><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocognitive><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurologic Disorders><Neurological Disorders><Neuromuscular Diseases><Neurons><Non-Polyadenylated RNA><Nuclear Inclusion><Nuclear Inclusion Bodies><Nuclear Magnetic Resonance Imaging><Nucleotides><Orphan Disease><Outcome><Outcome Measure><Oxidation-Reduction><Parkinsonian><Parkinsonian Condition><Parkinsonian Diseases><Parkinsonian Disorders><Parkinsonian Syndrome><Parkinsonism><Participant><Pathologic><Pathway interactions><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Pb element><Pharmaceutic Industry><Pharmaceutical Industry><Phase 2/3 trial><Phase II/III Trial><Phosphatides><Phospholipids><Pre-Clinical Model><Preclinical Models><Procedures><Property><Proteins><Protocol><Protocols documentation><Publishing><QOL><Quality of life><RNA><RNA Expression><RNA Gene Products><RNA-Binding Proteins><Rare Diseases><Rare Disorder><Reading><Redox><Renpenning syndrome 2><Reporting><Research><Research Infrastructure><Research Personnel><Researchers><Ribonucleic Acid><Sampling><Severities><Shipping><Site><Standardization><Steroid Compound><Steroids><Task Forces><Testing><Therapeutic><Time><Toxic effect><Toxicities><Training Activity><Training Programs><Transcription><Translation Initiation><Translations><Tremor><Tremor/Ataxia Syndrome><U-Series Cooperative Agreements><Ubiquitin><Validation><White Matter Disease><Woman><Work><X-linked mental deficiency-megalotestes syndrome><X-linked mental retardation with fragile X syndrome><X-linked mental retardation-fragile site 1 syndrome><Zeugmatography><advisory team><antisense oligo><astrogliosis><autism-fragile X (AFRAX) syndrome><balance><balance function><bio-markers><biologic marker><biomarker><brain MR imaging><brain MRI><brain magnetic resonance imaging><brain visualization><brain volume><cell stress><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><clinical outcome assessment><clinical outcome measures><clinical trial readiness><cognitive dysfunction><cognitive loss><data base><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><digital><electronic><electronic device><enroll><fra(X) syndrome><fra(X)(28) syndrome><fra(X)(q27) syndrome><fra(X)(q27-28) syndrome><fragile X associated tremor ataxia syndrome><fragile X-associated tremor/ataxia syndrome><fragile X-mental retardation syndrome><fragile Xq syndrome><fragile site mental retardation 1><gamma-Aminobutyric Acid Agonists><heavy metal Pb><heavy metal lead><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><mRNA><mRNP><macro-orchidism-marker X (MOMX) syndrome><macro-orchidism-marker X syndrome><mar(X) syndrome><marker X syndrome><measurable outcome><men><mental retardation-macroorchidism syndrome><messenger ribonucleoprotein><metabolism measurement><metabolomics><metabonomics><mitochondrial><mitochondrial dysfunction><myoneural disorder><neural inflammation><neurodegenerative illness><neuroinflammation><neuroinflammatory><neurological disease><neuromuscular degenerative disorder><neuromuscular disorder><neuronal><nuclear factor-erythroid 2><orphan disorder><outcome measurement><oxidation reduction reaction><pathway><primary end point><primary endpoint><recruit><repair><repaired><response><response to therapy><response to treatment><secondary end point><secondary endpoint><secondary outcome><sensor><substantia alba><therapeutic candidate><therapeutic response><therapy response><training module><translation><treatment response><treatment responsiveness><validations><white matter>
View Full Project Details on NIH Reporter
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DAVID R HESSL

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,169,064
FY 2025

Project Title

Clinical Outcome Assessment and Treatment Monitoring Markers for Clinical Trial Readiness in FXTAS

Grant Number:

1U01NS143225-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/15/2025

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a rare, inherited, X-linked, late-onset, progressive neurodegenerative disease characterized by intention tremor, cerebellar gait ataxia, parkinsonism, and cognitive decline. Pathologically, it features brain white matter degradation, ubiquitin-...

Research Terms

<APF-1><ATP-Dependent Proteolysis Factor 1><Action Tremors><Advisory Committees><Advocate><Allopregnanolone><Antisense Agent><Antisense Oligonucleotides><Ataxia><Ataxy><Atrophic><Atrophy><Biological Markers><Brain><Brain Nervous System><Brain Stem><Brain imaging><Brainstem><CGG repeat><Care Givers><Caregivers><Cellular Stress><Cellular Stress Response><Cerebellar Gait><Cerebellar Gait Ataxias><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Consensus><Cooperative Agreements><Coordination Impairment><Cytosine><Data Bases><Databases><Degenerative Neurologic Disorders><Detection><Disease><Disorder><Disturbance in cognition><Drug Industry><Dyssynergia><Electronics><Encephalon><Enrollment><Equilibrium><Escalante syndrome><Event><FDA approved><FXTAS><Fragile X><Fragile X Syndrome><Fragile X premutation-associated tremor ataxia syndrome><Future><GABA Agonists><GABA Receptor Agonists><Gait><Gene Transcription><Genes><Genetic Transcription><Guanine><HMG-20><Hereditary><High Mobility Protein 20><Image><Impaired cognition><Inflammation><Infrastructure><Inherited><Intention Tremor><Intranuclear Inclusion Bodies><Intranuclear Inclusions><Investigators><Lead><Link><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Martin-Bell Syndrome><Martin-Bell-Renpenning syndrome><Measurement><Measures><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Messenger RNA><Mitochondria><Modification><Molecular><Monitor><Motor><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><NF-E2 protein><NF-E2 transcription factor><NFE2 protein><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Nervous System Degenerative Diseases><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocognitive><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurologic Disorders><Neurological Disorders><Neuromuscular Diseases><Neurons><Non-Polyadenylated RNA><Nuclear Inclusion><Nuclear Inclusion Bodies><Nuclear Magnetic Resonance Imaging><Nucleotides><Orphan Disease><Outcome><Outcome Measure><Oxidation-Reduction><Parkinsonian><Parkinsonian Condition><Parkinsonian Diseases><Parkinsonian Disorders><Parkinsonian Syndrome><Parkinsonism><Participant><Pathologic><Pathway interactions><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Pb element><Pharmaceutic Industry><Pharmaceutical Industry><Phase 2/3 trial><Phase II/III Trial><Phosphatides><Phospholipids><Pre-Clinical Model><Preclinical Models><Procedures><Property><Proteins><Protocol><Protocols documentation><Publishing><QOL><Quality of life><RNA><RNA Expression><RNA Gene Products><RNA-Binding Proteins><Rare Diseases><Rare Disorder><Reading><Redox><Renpenning syndrome 2><Reporting><Research><Research Infrastructure><Research Personnel><Researchers><Ribonucleic Acid><Sampling><Severities><Shipping><Site><Standardization><Steroid Compound><Steroids><Task Forces><Testing><Therapeutic><Time><Toxic effect><Toxicities><Training Activity><Training Programs><Transcription><Translation Initiation><Translations><Tremor><Tremor/Ataxia Syndrome><U-Series Cooperative Agreements><Ubiquitin><Validation><White Matter Disease><Woman><Work><X-linked mental deficiency-megalotestes syndrome><X-linked mental retardation with fragile X syndrome><X-linked mental retardation-fragile site 1 syndrome><Zeugmatography><advisory team><antisense oligo><astrogliosis><autism-fragile X (AFRAX) syndrome><balance><balance function><bio-markers><biologic marker><biomarker><brain MR imaging><brain MRI><brain magnetic resonance imaging><brain visualization><brain volume><cell stress><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><clinical outcome assessment><clinical outcome measures><clinical trial readiness><cognitive dysfunction><cognitive loss><data base><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><digital><electronic><electronic device><enroll><fra(X) syndrome><fra(X)(28) syndrome><fra(X)(q27) syndrome><fra(X)(q27-28) syndrome><fragile X associated tremor ataxia syndrome><fragile X-associated tremor/ataxia syndrome><fragile X-mental retardation syndrome><fragile Xq syndrome><fragile site mental retardation 1><gamma-Aminobutyric Acid Agonists><heavy metal Pb><heavy metal lead><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><mRNA><mRNP><macro-orchidism-marker X (MOMX) syndrome><macro-orchidism-marker X syndrome><mar(X) syndrome><marker X syndrome><measurable outcome><men><mental retardation-macroorchidism syndrome><messenger ribonucleoprotein><metabolism measurement><metabolomics><metabonomics><mitochondrial><mitochondrial dysfunction><myoneural disorder><neural inflammation><neurodegenerative illness><neuroinflammation><neuroinflammatory><neurological disease><neuromuscular degenerative disorder><neuromuscular disorder><neuronal><nuclear factor-erythroid 2><orphan disorder><outcome measurement><oxidation reduction reaction><pathway><primary end point><primary endpoint><recruit><repair><repaired><response><response to therapy><response to treatment><secondary end point><secondary endpoint><secondary outcome><sensor><substantia alba><therapeutic candidate><therapeutic response><therapy response><training module><translation><treatment response><treatment responsiveness><validations><white matter>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Peter K Todd

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,169,064
FY 2025

Project Title

Clinical Outcome Assessment and Treatment Monitoring Markers for Clinical Trial Readiness in FXTAS

Grant Number:

1U01NS143225-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/15/2025

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a rare, inherited, X-linked, late-onset, progressive neurodegenerative disease characterized by intention tremor, cerebellar gait ataxia, parkinsonism, and cognitive decline. Pathologically, it features brain white matter degradation, ubiquitin-...

Research Terms

<APF-1><ATP-Dependent Proteolysis Factor 1><Action Tremors><Advisory Committees><Advocate><Allopregnanolone><Antisense Agent><Antisense Oligonucleotides><Ataxia><Ataxy><Atrophic><Atrophy><Biological Markers><Brain><Brain Nervous System><Brain Stem><Brain imaging><Brainstem><CGG repeat><Care Givers><Caregivers><Cellular Stress><Cellular Stress Response><Cerebellar Gait><Cerebellar Gait Ataxias><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Consensus><Cooperative Agreements><Coordination Impairment><Cytosine><Data Bases><Databases><Degenerative Neurologic Disorders><Detection><Disease><Disorder><Disturbance in cognition><Drug Industry><Dyssynergia><Electronics><Encephalon><Enrollment><Equilibrium><Escalante syndrome><Event><FDA approved><FXTAS><Fragile X><Fragile X Syndrome><Fragile X premutation-associated tremor ataxia syndrome><Future><GABA Agonists><GABA Receptor Agonists><Gait><Gene Transcription><Genes><Genetic Transcription><Guanine><HMG-20><Hereditary><High Mobility Protein 20><Image><Impaired cognition><Inflammation><Infrastructure><Inherited><Intention Tremor><Intranuclear Inclusion Bodies><Intranuclear Inclusions><Investigators><Lead><Link><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Martin-Bell Syndrome><Martin-Bell-Renpenning syndrome><Measurement><Measures><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Messenger RNA><Mitochondria><Modification><Molecular><Monitor><Motor><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><NF-E2 protein><NF-E2 transcription factor><NFE2 protein><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Nervous System Degenerative Diseases><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocognitive><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurologic Disorders><Neurological Disorders><Neuromuscular Diseases><Neurons><Non-Polyadenylated RNA><Nuclear Inclusion><Nuclear Inclusion Bodies><Nuclear Magnetic Resonance Imaging><Nucleotides><Orphan Disease><Outcome><Outcome Measure><Oxidation-Reduction><Parkinsonian><Parkinsonian Condition><Parkinsonian Diseases><Parkinsonian Disorders><Parkinsonian Syndrome><Parkinsonism><Participant><Pathologic><Pathway interactions><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Pb element><Pharmaceutic Industry><Pharmaceutical Industry><Phase 2/3 trial><Phase II/III Trial><Phosphatides><Phospholipids><Pre-Clinical Model><Preclinical Models><Procedures><Property><Proteins><Protocol><Protocols documentation><Publishing><QOL><Quality of life><RNA><RNA Expression><RNA Gene Products><RNA-Binding Proteins><Rare Diseases><Rare Disorder><Reading><Redox><Renpenning syndrome 2><Reporting><Research><Research Infrastructure><Research Personnel><Researchers><Ribonucleic Acid><Sampling><Severities><Shipping><Site><Standardization><Steroid Compound><Steroids><Task Forces><Testing><Therapeutic><Time><Toxic effect><Toxicities><Training Activity><Training Programs><Transcription><Translation Initiation><Translations><Tremor><Tremor/Ataxia Syndrome><U-Series Cooperative Agreements><Ubiquitin><Validation><White Matter Disease><Woman><Work><X-linked mental deficiency-megalotestes syndrome><X-linked mental retardation with fragile X syndrome><X-linked mental retardation-fragile site 1 syndrome><Zeugmatography><advisory team><antisense oligo><astrogliosis><autism-fragile X (AFRAX) syndrome><balance><balance function><bio-markers><biologic marker><biomarker><brain MR imaging><brain MRI><brain magnetic resonance imaging><brain visualization><brain volume><cell stress><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><clinical outcome assessment><clinical outcome measures><clinical trial readiness><cognitive dysfunction><cognitive loss><data base><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><digital><electronic><electronic device><enroll><fra(X) syndrome><fra(X)(28) syndrome><fra(X)(q27) syndrome><fra(X)(q27-28) syndrome><fragile X associated tremor ataxia syndrome><fragile X-associated tremor/ataxia syndrome><fragile X-mental retardation syndrome><fragile Xq syndrome><fragile site mental retardation 1><gamma-Aminobutyric Acid Agonists><heavy metal Pb><heavy metal lead><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><mRNA><mRNP><macro-orchidism-marker X (MOMX) syndrome><macro-orchidism-marker X syndrome><mar(X) syndrome><marker X syndrome><measurable outcome><men><mental retardation-macroorchidism syndrome><messenger ribonucleoprotein><metabolism measurement><metabolomics><metabonomics><mitochondrial><mitochondrial dysfunction><myoneural disorder><neural inflammation><neurodegenerative illness><neuroinflammation><neuroinflammatory><neurological disease><neuromuscular degenerative disorder><neuromuscular disorder><neuronal><nuclear factor-erythroid 2><orphan disorder><outcome measurement><oxidation reduction reaction><pathway><primary end point><primary endpoint><recruit><repair><repaired><response><response to therapy><response to treatment><secondary end point><secondary endpoint><secondary outcome><sensor><substantia alba><therapeutic candidate><therapeutic response><therapy response><training module><translation><treatment response><treatment responsiveness><validations><white matter>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David C Christiani

HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH, BOSTON, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,159,880
FY 2025

Project Title

The Boston Lung Cancer Survival Cohort

Grant Number:

5U01CA209414-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The Boston Lung Cancer Survival (BLCS) cohort is a Cancer Epidemiology Cohort of more than 12,000 lung cancer cases enrolled at Massachusetts General Hospital and the Dana-Farber Cancer Institute since 1992. This rich resource enables research to understand lung cancer heterogeneity that has already...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Air Pollution><Alternative Therapies><Alternative intervention><Archives><Award><Biological><Biological Markers><Blood Plasma><Blood Serum><Blood leukocyte><Body Tissues><Boston><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Cancer Center><Cancer Patient><Cancer Survivor><Cancer Survivorship><Cancer Treatment><Cancers><Cessation of life><Checkpoint inhibitor><Chest imaging><Clinical><Collaborations><Collection><Computed Tomography><Cooperative Agreements><Creativeness><DF/HCC><DNA><DNA mutation><Dana-Farber Cancer Institute><Data><Data Banks><Data Bases><Data Management Resources><Data Management System><Databanks><Databases><Death><Deoxyribonucleic Acid><Diagnosis><Diagnostic><Dimensions><Disease Progression><EGF Receptor><EGFR><EGFR Blocker><EGFR Inhibitor><EGFR Tyrosine Kinase Inhibitor><EGFR-TK Inhibitor><ERBB Protein><Economic Income><Economical Income><Education><Educational aspects><Electronic Health Record><Enrollment><Environment><Environmental Exposure><Epidemiologic Methodology><Epidemiologic Methods><Epidemiologic research methodology><Epidemiologic research methods><Epidemiological Methods><Epidemiological Techniques><Epidemiology><Epidermal Growth Factor Receptor><Epidermal Growth Factor Receptor Inhibitor><Epidermal Growth Factor Receptor Kinase><Epidermal Growth Factor Receptor Protein-Tyrosine Kinase><Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor><Epidermal Growth Factor-Urogastrone Receptors><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Erlotinib><Evaluation><Funding><Gefitinib><General Hospitals><Genetic><Genetic Change><Genetic defect><Genetic mutation><Genomics><Grant><HER1><Health><Health Insurance><Heterogeneity><High Resolution Computed Tomography><History><Image><Immune checkpoint inhibitor><Immune mediated therapy><Immunologically Directed Therapy><Immunotherapy><Income><Individual><Infrastructure><Interdisciplinary Research><Interdisciplinary Study><International><Investigation><Investigators><Iressa><Laboratories><Leukocytes><Leukocytes Reticuloendothelial System><Libraries><Long-term Follow-up><Lung><Lung Adenocarcinoma><Lung Function Tests><Lung Respiratory System><MCF3><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of lung><Marrow leukocyte><Massachusetts><Measures><Medical Informatics><Meteorology><Methodology><Methods Epidemiology><Methods in epidemiology><Modeling><Molecular><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><Mutation><NSCLC><NSCLC - Non-Small Cell Lung Cancer><Natural History><Neighborhoods><Newly Diagnosed><Non-Polyadenylated RNA><Non-Small Cell Lung Cancer><Non-Small-Cell Lung Carcinoma><Nucleic Acids><Occupational><Oncogenic><Output><PET><PET Scan><PET imaging><PETSCAN><PETT><Paper><Participant><Pathology><Patients><Peripheral><Phenotype><Plasma><Plasma Serum><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Productivity><Prognostic Marker><Publishing><Pulmonary Cancer><Pulmonary function tests><Pulmonary malignant Neoplasm><QOL><Quality of life><Questionnaires><RNA><RNA Gene Products><ROS1><ROS1 gene><Race><Races><Rad.-PET><Recording of previous events><Research><Research Personnel><Research Resources><Research Specimen><Researchers><Resource Sharing><Resources><Reticuloendothelial System, Serum, Plasma><Ribonucleic Acid><Risk Factors><Sampling><Serum><Smoking><Socio-economic status><Socioeconomic Status><Source><Specimen><Survivors><TGF-alpha Receptor><Tarceva><Therapeutic><Thoracic imaging><Tissue Arrays><Tissue Banks><Tissue Chip><Tissue Collection><Tissue Microarray><Tissue Survival><Tissue repository><Tissues><Tomodensitometry><Transforming Growth Factor alpha Receptor><Translational Research><Translational Science><Treatment outcome><Treatment-related toxicity><Tumor Tissue><U-Series Cooperative Agreements><Update><Urine><Urogastrone Receptor><White Blood Cells><White Cell><Work><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><active followup><adulthood><anti-cancer research><anti-cancer therapy><automated image analysis><bio-informatics infrastructure><bio-markers><biobank><bioinformatics infrastructure><biologic><biologic marker><biomarker><biorepository><built environment><c-erbB-1><c-erbB-1 Protein><cancer diagnosis><cancer epidemiology><cancer heterogeneity><cancer research><cancer survival><cancer therapy><cancer-directed therapy><catscan><clinical investigation><co-morbid><co-morbidity><cohort><comorbidity><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><creativity><data base><data depository><data management><data repository><data set repository><dataset repository><depository><dietary><disparities in race><disparities in treatment><disparity due to race><driver lesion><driver mutation><economic determinant><effective therapy><effective treatment><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><empowerment><enroll><epidemiologic><epidemiologic discoveries><epidemiological><epigenetically><erbB-1><erbB-1 Proto-Oncogene Protein><erbBl><follow up><follow-up><followed up><followup><genetic epidemiologic study><genetic epidemiology><genome mutation><genotyped patients><health insurance plan><high resolution CT><histories><imaging><immune check point inhibitor><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><improved><income insurance><incomes><indexing><inequality due to race><inequality in treatment><inequity due to race><innovate><innovation><innovative><long-term followup><lung cancer><lung cancer early detection><lung cancer screening><lung function><malignancy><method development><minority patient><mortality><multidisciplinary><mutational status><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutics><new therapy><new therapy approaches><new treatment approach><new treatment strategy><next generation therapeutics><non-contrast CT><noncontrast CT><noncontrast computed tomography><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutics><novel therapy><novel therapy approach><patients from minority><patients of minority><phenome><phenomics><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><prognostic><prognostic biomarker><prognostic indicator><programs><proto-oncogene protein c-erbB-1><pulmonary function><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial><racial background><racial disparity><racial inequality><racial inequity><racial origin><racially unequal><radiomics><recruit><repository><response><response to therapy><response to treatment><segregation><social determinants><socio-economic><socio-economic position><socio-economically><sociodeterminant><socioeconomic position><socioeconomically><socioeconomics><survival outcome><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic response><therapeutic toxicity><therapy associated toxicity><therapy related toxicity><therapy response><therapy toxicity><traditional therapy><translation research><translational investigation><translational medicine><treatment disparity><treatment inequality><treatment inequity><treatment response><treatment responsiveness><treatment strategy><treatment toxicity><treatment-associated toxicity><tumor><v-ROS Avian UR2 Sarcoma Virus Oncogene Homolog 1><vaping><white blood cell><white blood corpuscle>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sina Farsiu

DUKE UNIVERSITY, DURHAM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,105,585
FY 2025

Project Title

Blink, Lacrimation, and Nociception: Precision Mapping and Integrated Atlas Generation of Corneal Trigeminal Afferents

Grant Number:

5U01EY034687-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Corneal nerves that mediate pain, blink reflexes and tear production are indispensable in the proper maintenance of ocular surface homeostasis. However, the complexity of these neurons, both at the axon level in the cornea, and cell bodies in the trigeminal ganglion, has made it increasingl...

Research Terms

<3-D><3-Dimensional><3D><AI Augmented><AI assisted><AI based><AI based method><AI driven><AI enhanced><AI integrated><AI powered><Ablation><Anatomic Sites><Anatomic structures><Anatomy><Artificial Intelligence enhanced><Assay><Atlases><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autoregulation><Axon><Behavioral><Bioassay><Biological Assay><Blinking><Body Tissues><Brain Stem><Brainstem><Catalogs><Categories><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Classification><Clinical Research><Clinical Study><Color><Complex><Computer software><Cornea><Corneal infection><Coupled><Data><Data Set><Development><Dimensions><Disabling><Dissection><Dry Eye Syndromes><Dry eye disease><Electrophysiology><Electrophysiology (science)><Eye><Eye pain><Eyeball><Foundations><Future><Gasser's Ganglion><Gasserian Ganglion><Generations><Genes><Genetic><Genomics><Grant><Grips><Homeostasis><Human><Image><Image Analyses><Image Analysis><Immunofluorescence><Immunofluorescence Immunologic><Intracellular Communication and Signaling><Ions><Keratoconjunctivitis Sicca><Knowledge><Label><Lacrimal deficiency><Lacrimal secretion><Lacrimation><Link><Machine Learning><Macrophage><Maintenance><Maps><Mediating><Mice><Mice Mammals><Microbial keratitis><Microscopy><Modeling><Modern Man><Molecular><Morphology><Mouse Strains><Murine><Mus><Mφ><Nature><Nerve><Nerve Cells><Nerve Fibers><Nerve Impulse Transmission><Nerve Plexus><Nerve Transmission><Nerve Unit><Neural Cell><Neurocyte><Neuronal Transmission><Neurons><Neuropathy><Neurophysiology / Electrophysiology><Nociception><Nociceptors><Ocular desiccation><Output><P aeruginosa><P. aeruginosa><Pain><Painful><Pattern><Physiological Homeostasis><Population><Process><Property><Pseudomonas aeruginosa><Pseudomonas pyocyanea><QOL><Quality of life><RNA Seq><RNA sequencing><RNAseq><Reflex><Reflex action><Resolution><Semilunar Ganglion><Signal Transduction><Signal Transduction Systems><Signaling><Software><Structure><Structure of trigeminal ganglion><Systematics><Tissues><Translational Research><Translational Science><Trigeminal Ganglias><Trigeminal Ganglion><Trigeminal System><Validation><Work><analog><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence method><artificial intelligence powered><auto-segmentation><automated segmentation><automatic segmentation><autosegmentation><axon signaling><axon-glial signaling><axonal signaling><behavior prediction><behavioral prediction><biological signal transduction><blink reflexes><catalog><corneal><density><developmental><differential expression><differentially expressed><dry eye><electrophysiological><enhanced with AI><enhanced with Artificial Intelligence><experiment><experimental research><experimental study><experiments><eye blink><eye blink reflex><eye dryness><eyeblink><eyeblink reflex><genetic approach><genetic strategy><glia signaling><glial signaling><global gene expression><global transcription profile><grasp><human subject><image evaluation><image interpretation><imaging><imaging Segmentation><in vivo confocal microscopy><infections in the cornea><infectious keratitis><machine based learning><machine learning based classification><machine learning classification><multidisciplinary><multiple data sets><multiple datasets><nerve signaling><neural signaling><neuronal><neuronal circuit><neuronal circuitry><neuronal signaling><neuropathic><neurotransmission><new approaches><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><nociceptive><nociceptive neurons><novel approaches><novel drug target><novel druggable target><novel pharmacotherapy target><novel strategies><novel strategy><novel therapeutic target><novel therapy target><ocular dryness><ocular pain><ocular signs of dryness><ocular surface><ocular surface dryness><open source><optical blink reflex><pain-sensing neurons><pain-sensing sensory neurons><pain-sensing somatosensory neurons><patch clamp><pharmacologic><reflectance confocal microscopy><resolutions><response><segmentation algorithm><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><tear deficiency><tear production><tear secretion><three dimensional><transcriptional differences><transcriptome><transcriptome sequencing><transcriptomic sequencing><translation research><translational investigation><trigeminal><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Victor L Perez

DUKE UNIVERSITY, DURHAM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,105,585
FY 2025

Project Title

Blink, Lacrimation, and Nociception: Precision Mapping and Integrated Atlas Generation of Corneal Trigeminal Afferents

Grant Number:

5U01EY034687-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Corneal nerves that mediate pain, blink reflexes and tear production are indispensable in the proper maintenance of ocular surface homeostasis. However, the complexity of these neurons, both at the axon level in the cornea, and cell bodies in the trigeminal ganglion, has made it increasingl...

Research Terms

<3-D><3-Dimensional><3D><AI Augmented><AI assisted><AI based><AI based method><AI driven><AI enhanced><AI integrated><AI powered><Ablation><Anatomic Sites><Anatomic structures><Anatomy><Artificial Intelligence enhanced><Assay><Atlases><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autoregulation><Axon><Behavioral><Bioassay><Biological Assay><Blinking><Body Tissues><Brain Stem><Brainstem><Catalogs><Categories><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Classification><Clinical Research><Clinical Study><Color><Complex><Computer software><Cornea><Corneal infection><Coupled><Data><Data Set><Development><Dimensions><Disabling><Dissection><Dry Eye Syndromes><Dry eye disease><Electrophysiology><Electrophysiology (science)><Eye><Eye pain><Eyeball><Foundations><Future><Gasser's Ganglion><Gasserian Ganglion><Generations><Genes><Genetic><Genomics><Grant><Grips><Homeostasis><Human><Image><Image Analyses><Image Analysis><Immunofluorescence><Immunofluorescence Immunologic><Intracellular Communication and Signaling><Ions><Keratoconjunctivitis Sicca><Knowledge><Label><Lacrimal deficiency><Lacrimal secretion><Lacrimation><Link><Machine Learning><Macrophage><Maintenance><Maps><Mediating><Mice><Mice Mammals><Microbial keratitis><Microscopy><Modeling><Modern Man><Molecular><Morphology><Mouse Strains><Murine><Mus><Mφ><Nature><Nerve><Nerve Cells><Nerve Fibers><Nerve Impulse Transmission><Nerve Plexus><Nerve Transmission><Nerve Unit><Neural Cell><Neurocyte><Neuronal Transmission><Neurons><Neuropathy><Neurophysiology / Electrophysiology><Nociception><Nociceptors><Ocular desiccation><Output><P aeruginosa><P. aeruginosa><Pain><Painful><Pattern><Physiological Homeostasis><Population><Process><Property><Pseudomonas aeruginosa><Pseudomonas pyocyanea><QOL><Quality of life><RNA Seq><RNA sequencing><RNAseq><Reflex><Reflex action><Resolution><Semilunar Ganglion><Signal Transduction><Signal Transduction Systems><Signaling><Software><Structure><Structure of trigeminal ganglion><Systematics><Tissues><Translational Research><Translational Science><Trigeminal Ganglias><Trigeminal Ganglion><Trigeminal System><Validation><Work><analog><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence method><artificial intelligence powered><auto-segmentation><automated segmentation><automatic segmentation><autosegmentation><axon signaling><axon-glial signaling><axonal signaling><behavior prediction><behavioral prediction><biological signal transduction><blink reflexes><catalog><corneal><density><developmental><differential expression><differentially expressed><dry eye><electrophysiological><enhanced with AI><enhanced with Artificial Intelligence><experiment><experimental research><experimental study><experiments><eye blink><eye blink reflex><eye dryness><eyeblink><eyeblink reflex><genetic approach><genetic strategy><glia signaling><glial signaling><global gene expression><global transcription profile><grasp><human subject><image evaluation><image interpretation><imaging><imaging Segmentation><in vivo confocal microscopy><infections in the cornea><infectious keratitis><machine based learning><machine learning based classification><machine learning classification><multidisciplinary><multiple data sets><multiple datasets><nerve signaling><neural signaling><neuronal><neuronal circuit><neuronal circuitry><neuronal signaling><neuropathic><neurotransmission><new approaches><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><nociceptive><nociceptive neurons><novel approaches><novel drug target><novel druggable target><novel pharmacotherapy target><novel strategies><novel strategy><novel therapeutic target><novel therapy target><ocular dryness><ocular pain><ocular signs of dryness><ocular surface><ocular surface dryness><open source><optical blink reflex><pain-sensing neurons><pain-sensing sensory neurons><pain-sensing somatosensory neurons><patch clamp><pharmacologic><reflectance confocal microscopy><resolutions><response><segmentation algorithm><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><tear deficiency><tear production><tear secretion><three dimensional><transcriptional differences><transcriptome><transcriptome sequencing><transcriptomic sequencing><translation research><translational investigation><trigeminal><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Daniel Raphael Saban

DUKE UNIVERSITY, DURHAM, NC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,105,585
FY 2025

Project Title

Blink, Lacrimation, and Nociception: Precision Mapping and Integrated Atlas Generation of Corneal Trigeminal Afferents

Grant Number:

5U01EY034687-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Corneal nerves that mediate pain, blink reflexes and tear production are indispensable in the proper maintenance of ocular surface homeostasis. However, the complexity of these neurons, both at the axon level in the cornea, and cell bodies in the trigeminal ganglion, has made it increasingl...

Research Terms

<3-D><3-Dimensional><3D><AI Augmented><AI assisted><AI based><AI based method><AI driven><AI enhanced><AI integrated><AI powered><Ablation><Anatomic Sites><Anatomic structures><Anatomy><Artificial Intelligence enhanced><Assay><Atlases><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Autoregulation><Axon><Behavioral><Bioassay><Biological Assay><Blinking><Body Tissues><Brain Stem><Brainstem><Catalogs><Categories><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Classification><Clinical Research><Clinical Study><Color><Complex><Computer software><Cornea><Corneal infection><Coupled><Data><Data Set><Development><Dimensions><Disabling><Dissection><Dry Eye Syndromes><Dry eye disease><Electrophysiology><Electrophysiology (science)><Eye><Eye pain><Eyeball><Foundations><Future><Gasser's Ganglion><Gasserian Ganglion><Generations><Genes><Genetic><Genomics><Grant><Grips><Homeostasis><Human><Image><Image Analyses><Image Analysis><Immunofluorescence><Immunofluorescence Immunologic><Intracellular Communication and Signaling><Ions><Keratoconjunctivitis Sicca><Knowledge><Label><Lacrimal deficiency><Lacrimal secretion><Lacrimation><Link><Machine Learning><Macrophage><Maintenance><Maps><Mediating><Mice><Mice Mammals><Microbial keratitis><Microscopy><Modeling><Modern Man><Molecular><Morphology><Mouse Strains><Murine><Mus><Mφ><Nature><Nerve><Nerve Cells><Nerve Fibers><Nerve Impulse Transmission><Nerve Plexus><Nerve Transmission><Nerve Unit><Neural Cell><Neurocyte><Neuronal Transmission><Neurons><Neuropathy><Neurophysiology / Electrophysiology><Nociception><Nociceptors><Ocular desiccation><Output><P aeruginosa><P. aeruginosa><Pain><Painful><Pattern><Physiological Homeostasis><Population><Process><Property><Pseudomonas aeruginosa><Pseudomonas pyocyanea><QOL><Quality of life><RNA Seq><RNA sequencing><RNAseq><Reflex><Reflex action><Resolution><Semilunar Ganglion><Signal Transduction><Signal Transduction Systems><Signaling><Software><Structure><Structure of trigeminal ganglion><Systematics><Tissues><Translational Research><Translational Science><Trigeminal Ganglias><Trigeminal Ganglion><Trigeminal System><Validation><Work><analog><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence based><artificial intelligence driven><artificial intelligence integrated><artificial intelligence method><artificial intelligence powered><auto-segmentation><automated segmentation><automatic segmentation><autosegmentation><axon signaling><axon-glial signaling><axonal signaling><behavior prediction><behavioral prediction><biological signal transduction><blink reflexes><catalog><corneal><density><developmental><differential expression><differentially expressed><dry eye><electrophysiological><enhanced with AI><enhanced with Artificial Intelligence><experiment><experimental research><experimental study><experiments><eye blink><eye blink reflex><eye dryness><eyeblink><eyeblink reflex><genetic approach><genetic strategy><glia signaling><glial signaling><global gene expression><global transcription profile><grasp><human subject><image evaluation><image interpretation><imaging><imaging Segmentation><in vivo confocal microscopy><infections in the cornea><infectious keratitis><machine based learning><machine learning based classification><machine learning classification><multidisciplinary><multiple data sets><multiple datasets><nerve signaling><neural signaling><neuronal><neuronal circuit><neuronal circuitry><neuronal signaling><neuropathic><neurotransmission><new approaches><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><nociceptive><nociceptive neurons><novel approaches><novel drug target><novel druggable target><novel pharmacotherapy target><novel strategies><novel strategy><novel therapeutic target><novel therapy target><ocular dryness><ocular pain><ocular signs of dryness><ocular surface><ocular surface dryness><open source><optical blink reflex><pain-sensing neurons><pain-sensing sensory neurons><pain-sensing somatosensory neurons><patch clamp><pharmacologic><reflectance confocal microscopy><resolutions><response><segmentation algorithm><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><tear deficiency><tear production><tear secretion><three dimensional><transcriptional differences><transcriptome><transcriptome sequencing><transcriptomic sequencing><translation research><translational investigation><trigeminal><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MELISSA M HUDSON

ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MEMPHIS, TN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,059,908
FY 2025

Project Title

The St. Jude Lifetime Cohort Study

Grant Number:

1U01CA301480-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2025

End Date:

7/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The number of survivors of childhood/adolescent cancer in the US will approach 580,000 by 2040. This growing population is at risk for a spectrum of physical and psychosocial effects that are multifactorial in etiology. Recognition of associations of treatment-related complications with poor quality...

Research Terms

<21+ years old><ASCVD><Active Follow-up><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adverse effects><Age><Aging><Area><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Attention><Automobile Driving><Award><Biologic Factor><Biological Factors><Biological Specimen Banks><Biological Substance Banks><Brain><Brain Nervous System><Brain imaging><Cancers><Cardiovascular Diseases><Caring><Causality><Characteristics><Childhood><Childhood Cancer Treatment><Childhood Cancers><Chronic><Chronic Disease><Chronic Illness><Clinical><Clinical assessments><Cohort Studies><Collaborations><Concurrent Studies><Detection><Disease Marker><Disease Progression><Dysfunction><Early Diagnosis><Early identification><Electromyography><Eligibility><Eligibility Determination><Encephalon><Enrollment><Environmental Factor><Environmental Risk Factor><Etiology><Evolution><Functional Imaging><Functional MRI><Functional Magnetic Resonance Imaging><Functional disorder><Funding><Future><General Population><General Public><Generations><Germ Lines><Goals><Grant><Health><Health Promotion><Health behavior><Impairment><Impoverished><Infrastructure><Intervention><Investigation><Investigators><Knowledge><Life><Lipoprotein (a)><Lipoprotein Lp(a)><Lp(a)><MR Spectroscopy><Magnetic Resonance Spectroscopy><Malignant Childhood Neoplasm><Malignant Childhood Tumor><Malignant Neoplasms><Malignant Pediatric Neoplasm><Malignant Pediatric Tumor><Malignant Tumor><Malignant childhood cancer><Manuscripts><Memory><Muscle><Muscle Tissue><NIH><National Institutes of Health><Neighborhoods><Nerve Conduction><Neural Conduction><Neurocognitive><Outcome><Participant><Pathway interactions><Pediatric Cancer Treatment><Phenotype><Physiologic><Physiologic Imaging><Physiological><Physiopathology><Population><Poverty><Premature Mortality><Protocol Screening><Psychological Factors><Psychosocial Effect><Publications><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Reduction><Saint Jude><Saint Jude Children's Cancer Center><Saint Jude Children's Research Hospital><Salutogenesis><Scientific Publication><Screening for cancer><Severities><Sleep Architecture><Sleep Disorders><St. Jude><St. Jude Children's Cancer Center><St. Jude Children's Research Hospital><St. Jude Children's Research Hospital Comprehensive Cancer Center><St.Jude Children's Cancer Center><St.Jude Children's Research Hospital><St.Jude Children's Research Hospital Comprehensive Cancer Center><Surface><Survivors><Testing><Treatment/Psychosocial Effects><United States National Institutes of Health><Work><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><adverse consequence><adverse outcome><age acceleration><ages><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><biological specimen repository><biosample repository><biospecimen bank><biospecimen repository><brain visualization><cancer in a child><cancer in children><cancer survivor care><cancer survivorship care><cardiovascular disorder><causation><child with cancer><childhood cancer survivor><childhood malignancy><chronic disorder><cognitive enhancement><cognitive neuroscience><cohort><coronary artery calcium scoring><coronary calcium scoring><data access><data portal><data sharing><data sharing portal><deprivation><disease causation><disease phenotype><disease risk><disorder risk><disparity in health><driving><early cancer detection><early detection><enroll><entire genome><environmental risk><executive control><executive function><fMRI><fNIRS><follow up><follow-up><followed up><followup><full genome><functional near infrared spectroscopy><genome sequencing><health assessment><health disparity><health related behavior><high risk><improved><juvenile><juvenile human><life span><lifespan><malignancy><metabolic imaging><mortality><multimorbidity><multiple chronic conditions><muscle bulk><muscle form><muscle mass><muscle strength><muscular><neoplasm/cancer><neuromuscular><new drug treatments><new drugs><new marker><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel biomarker><novel drug treatments><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathophysiology><pathway><pediatric><pediatric cancer><pediatric cancer survivor><pediatric malignancy><physiological imaging><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><promoting health><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><remediation><risk mitigation><risk prediction algorithm><risk prediction model><risk stratification><risk-reducing><screening cancer patients><sleep diseases><sleep dysfunction><sleep illness><sleep problem><social><social factors><social health determinants><social integration><specimen bank><specimen repository><stratify risk><survivorship><therapeutic stratification><tool><treatment stratification><ultrasound><whole genome>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kirsten Kimberlie Ness

ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MEMPHIS, TN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,059,908
FY 2025

Project Title

The St. Jude Lifetime Cohort Study

Grant Number:

1U01CA301480-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2025

End Date:

7/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The number of survivors of childhood/adolescent cancer in the US will approach 580,000 by 2040. This growing population is at risk for a spectrum of physical and psychosocial effects that are multifactorial in etiology. Recognition of associations of treatment-related complications with poor quality...

Research Terms

<21+ years old><ASCVD><Active Follow-up><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adverse effects><Age><Aging><Area><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Attention><Automobile Driving><Award><Biologic Factor><Biological Factors><Biological Specimen Banks><Biological Substance Banks><Brain><Brain Nervous System><Brain imaging><Cancers><Cardiovascular Diseases><Caring><Causality><Characteristics><Childhood><Childhood Cancer Treatment><Childhood Cancers><Chronic><Chronic Disease><Chronic Illness><Clinical><Clinical assessments><Cohort Studies><Collaborations><Concurrent Studies><Detection><Disease Marker><Disease Progression><Dysfunction><Early Diagnosis><Early identification><Electromyography><Eligibility><Eligibility Determination><Encephalon><Enrollment><Environmental Factor><Environmental Risk Factor><Etiology><Evolution><Functional Imaging><Functional MRI><Functional Magnetic Resonance Imaging><Functional disorder><Funding><Future><General Population><General Public><Generations><Germ Lines><Goals><Grant><Health><Health Promotion><Health behavior><Impairment><Impoverished><Infrastructure><Intervention><Investigation><Investigators><Knowledge><Life><Lipoprotein (a)><Lipoprotein Lp(a)><Lp(a)><MR Spectroscopy><Magnetic Resonance Spectroscopy><Malignant Childhood Neoplasm><Malignant Childhood Tumor><Malignant Neoplasms><Malignant Pediatric Neoplasm><Malignant Pediatric Tumor><Malignant Tumor><Malignant childhood cancer><Manuscripts><Memory><Muscle><Muscle Tissue><NIH><National Institutes of Health><Neighborhoods><Nerve Conduction><Neural Conduction><Neurocognitive><Outcome><Participant><Pathway interactions><Pediatric Cancer Treatment><Phenotype><Physiologic><Physiologic Imaging><Physiological><Physiopathology><Population><Poverty><Premature Mortality><Protocol Screening><Psychological Factors><Psychosocial Effect><Publications><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Reduction><Saint Jude><Saint Jude Children's Cancer Center><Saint Jude Children's Research Hospital><Salutogenesis><Scientific Publication><Screening for cancer><Severities><Sleep Architecture><Sleep Disorders><St. Jude><St. Jude Children's Cancer Center><St. Jude Children's Research Hospital><St. Jude Children's Research Hospital Comprehensive Cancer Center><St.Jude Children's Cancer Center><St.Jude Children's Research Hospital><St.Jude Children's Research Hospital Comprehensive Cancer Center><Surface><Survivors><Testing><Treatment/Psychosocial Effects><United States National Institutes of Health><Work><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><adverse consequence><adverse outcome><age acceleration><ages><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><biological specimen repository><biosample repository><biospecimen bank><biospecimen repository><brain visualization><cancer in a child><cancer in children><cancer survivor care><cancer survivorship care><cardiovascular disorder><causation><child with cancer><childhood cancer survivor><childhood malignancy><chronic disorder><cognitive enhancement><cognitive neuroscience><cohort><coronary artery calcium scoring><coronary calcium scoring><data access><data portal><data sharing><data sharing portal><deprivation><disease causation><disease phenotype><disease risk><disorder risk><disparity in health><driving><early cancer detection><early detection><enroll><entire genome><environmental risk><executive control><executive function><fMRI><fNIRS><follow up><follow-up><followed up><followup><full genome><functional near infrared spectroscopy><genome sequencing><health assessment><health disparity><health related behavior><high risk><improved><juvenile><juvenile human><life span><lifespan><malignancy><metabolic imaging><mortality><multimorbidity><multiple chronic conditions><muscle bulk><muscle form><muscle mass><muscle strength><muscular><neoplasm/cancer><neuromuscular><new drug treatments><new drugs><new marker><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel biomarker><novel drug treatments><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathophysiology><pathway><pediatric><pediatric cancer><pediatric cancer survivor><pediatric malignancy><physiological imaging><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><promoting health><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><remediation><risk mitigation><risk prediction algorithm><risk prediction model><risk stratification><risk-reducing><screening cancer patients><sleep diseases><sleep dysfunction><sleep illness><sleep problem><social><social factors><social health determinants><social integration><specimen bank><specimen repository><stratify risk><survivorship><therapeutic stratification><tool><treatment stratification><ultrasound><whole genome>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SIMON J FISHER

UNIVERSITY OF KENTUCKY, LEXINGTON, KY

Good lead · 68/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$790,957
FY 2026

Project Title

Restoration of Impaired Awareness of Hypoglycemia U01 Consortium: University of Kentucky

Grant Number:

5U01DK135111-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2022

End Date:

12/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

“Restoration of Impaired Awareness of Hypoglycemia U01 Consortium: University of Kentucky” Abstract For insulin-treated people with Type 1 Diabetes (T1D), hypoglycemia is the rate limiting step in their goals to appropriately control their blood sugar and avoid long-term diabetes complications. Unfo...

Research Terms

<21+ years old><Active Follow-up><Adult><Adult Human><Age><Applications Grants><Awareness><Blood Glucose><Blood Sugar><Brittle Diabetes Mellitus><Caring><Clampings><Clinical Research><Clinical Study><Closure by clamp><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Cooperative Agreements><Coupled><D-Glucose><Development><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Education><Educational aspects><Endocrine Gland Secretion><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Event><Failure><Frequencies><Glucose><Glucose Clamp><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Grant Proposals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><Heterogeneity><Hormones><Humulin R><Hybrids><Hyperinsulinemic Clamp><Hypoglycemia><IDDM><Impairment><Individual><Infrastructure><Institution><Insulin><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intervention><Juvenile-Onset Diabetes Mellitus><Kentucky><Ketosis-Prone Diabetes Mellitus><Leadership><Life><Measurement><Measures><Metabolic><Methodology><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Novolin R><Pathologic Processes><Pathological Processes><Patient Self-Report><Patients><Persons><Physiologic><Physiological><Play><Questionnaires><R-Series Research Projects><R01 Mechanism><R01 Program><Recurrence><Recurrent><Regular Insulin><Research><Research Grants><Research Project Grants><Research Projects><Risk><Role><Rural><Self-Report><Severities><Site><Study Subject><Sudden-Onset Diabetes Mellitus><Symptoms><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><U-Series Cooperative Agreements><Universities><active followup><adulthood><ages><burden of disease><burden of illness><clinical research site><clinical site><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><counterregulation><developmental><diabetes><disease burden><experience><follow up><follow-up><followed up><followup><hemoglobin A1c><hypoglycemic><hypoglycemic episodes><improved><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><new approaches><novel><novel approaches><novel strategies><novel strategy><recruit><response><restoration><social role><type I diabetes><type one diabetes>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARISA ROBERTO

SCRIPPS RESEARCH INSTITUTE, THE, LA JOLLA, CA

Good lead · 68/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$679,978
FY 2026

Project Title

9/10 Electrophysiology of Alcohol in Extended Amygdala

Grant Number:

5U01AA013498-25

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/27/2001

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

This is a competitive U01 renewal application under the Integrative Neuroscience Initiative on Alcoholism- Neuroimmune (INIA-N) Consortium (Notice# RFA-AA-20-11/12/13). It is designed to integrate multidisciplinary research projects based on the genomic, cellular, and behavioral neuroadaptations rel...

Research Terms

<4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><Absolute ethanol><Actemra><Alcohol Chemical Class><Alcohol Drinking><Alcohol consumption><Alcohol withdrawal syndrome><Alcoholism><Alcohols><Aminalon><Aminalone><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Animals><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Area><Assay><Astrocytes><Astrocytus><Astroglia><Automobile Driving><B cell differentiation factor><B cell stimulating factor 2><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Basic Research><Basic Science><Behavioral><Beta Proprotein Interleukin 1><Bioassay><Biochemical><Biological Assay><Brain><Brain Nervous System><Brain region><CD126 Antigens><CD126 Receptor><CSIF><CSIF-10><Cell Body><Cell Communication and Signaling><Cell Nucleus><Cell Signaling><Cells><Chronic><Collaborations><Connector Neuron><Coping Behavior><Cytokine Synthesis Inhibitory Factor><Data><Dedications><Dependence><Development><Drug Therapy><Drugs><ETOH><Electrophysiology><Electrophysiology (science)><Encephalon><EtOH drinking><EtOH use><Ethanol><Ethanol dependence><Ethyl Alcohol><Female><GABA><GP130><Genes><Genomics><Glia><Glial Cells><Glutamates><Grain Alcohol><Grant><HPGF><Heavy Drinking><Hepatocyte-Stimulating Factor><Homolog of Drosophila TOLL><Hortega cell><Human><Human Resources><Hybridoma Growth Factor><IFN-beta 2><IFNB2><IL-1 beta><IL-1 β><IL-1-b><IL-10><IL-1β><IL-6><IL-6 Receptors><IL-6 inhibitor><IL1-Beta><IL1-β><IL10><IL10A><IL1B Protein><IL1F2><IL1β><IL6 Protein><IL6 Receptors><IL6 inhibitor><IL6ST><IL6ST gene><Immune><Immune Targeting><Immune response><Immunes><Immunoblotting><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Impairment><In Vitro><Inflammation><Inflammatory><Intercalary Neuron><Intercalated Neurons><Interdisciplinary Research><Interdisciplinary Study><Interleukin 10 Precursor><Interleukin 1beta><Interleukin 6 Receptor><Interleukin 6 Signal Transducer><Interleukin Activation><Interleukin-1 beta><Interleukin-10><Interleukin-1β><Interleukin-6><Interleukin-6 inhibitor><Interneurons><Internuncial Cell><Internuncial Neuron><Intracellular Communication and Signaling><Investigators><KO mice><Knock-out Mice><Knockout Mice><Kolliker's reticulum><L-Glutamate><M mulatta><M. mulatta><MGI-2><Macaca mulatta><Macaca rhesus><Manpower><Medial><Mediating><Mediator><Medication><Methylcarbinol><Mice><Mice Mammals><Microglia><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Murine><Mus><Mutant Strains Mice><Myeloid Differentiation-Inducing Protein><Nerve Cells><Nerve Unit><Neural Cell><Neural Transmission><Neurocyte><Neuroglia><Neuroglial Cells><Neuroimmune><Neuroimmune system><Neurons><Neurophysiology / Electrophysiology><Neurosciences><Non-Polyadenylated RNA><Non-neuronal cell><Nonneuronal cell><Nucleus><Null Mouse><Pathogenesis><Pathway interactions><Pharmaceutical Preparations><Pharmacological Treatment><Pharmacotherapy><Physiologic><Physiological><Plasmacytoma Growth Factor><Play><Prefrontal Cortex><Preinterleukin 1 Beta><Property><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><RNA><RNA Gene Products><RNA Seq><RNA sequencing><RNAseq><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Rhesus Macaque><Rhesus Monkey><RiboTag><Ribonucleic Acid><Rodent><Rodentia><Rodents Mammals><Role><STAT3><STAT3 gene><Scientific Publication><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Stress and Coping><Synapses><Synaptic><Synaptic Transmission><System><TLR4><TLR4 gene><Testing><Toll Homologue><Transgenic Mice><Transgenic Organisms><Translating><Transmission><Viral Vector><Western Blotting><Western Immunoblotting><Withdrawal><addiction><addictive disorder><alcohol behavior><alcohol effect><alcohol induced behavior><alcohol ingestion><alcohol intake><alcohol preferring rats><alcohol product use><alcohol related behavior><alcohol use><alcohol use disorder><alcohol withdrawal><alcoholic beverage consumption><alcoholic drink intake><amygdaloid nuclear complex><analog><anxiety-like behavior><astrocytic glia><behavior measurement><behavior phenotype><behavior study><behavioral measure><behavioral measurement><behavioral phenotyping><behavioral study><biological signal transduction><cell type><coping with stress><cytokine><design><designing><developmental><drink heavily><drinking><driving><drug candidate><drug intervention><drug treatment><drug/agent><electrophysiological><ethanol addiction><ethanol behavior><ethanol consumption><ethanol dependency><ethanol dependent><ethanol drinking><ethanol effect><ethanol induced behavior><ethanol ingestion><ethanol intake><ethanol perferring rats><ethanol product use><ethanol related behavior><ethanol use><ethanol use disorder><ethanol withdrawal><excessive alcohol consumption><excessive alcohol ingestion><excessive alcohol intake><excessive anxiety><excessive drinking><excessive ethanol ingestion><extreme drinking><gamma-Aminobutyric Acid><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><gitter cell><global gene expression><global transcription profile><glutamate signaling><glutamatergic><glutamatergic dendrodendritic synapses><glutamatergic signaling><gp130 Transducer Chain><heavy alcohol use><host response><immune system response><immunoresponse><inhibit IL-6><inhibit IL6><inhibit Interleukin-6><interferon beta 2><mRNA Expression><male><member><mesoglia><microglial cell><microgliocyte><mouse mutant><negative affect><negative affectivity><negative emotional state><nerve cement><neural adaptation><neuroadaptation><neuronal><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><overexpress><overexpression><pathway><perivascular glial cell><personnel><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><protein blotting><response><sex><social role><stress-related coping><synapse><therapeutic target><tocilizumab><toll-like receptor 4><transcriptome><transcriptome sequencing><transcriptomic sequencing><transcriptomics><transgenic><translational opportunities><translational potential><transmission process><vector induced><withdrawal from alcohol><γ-Aminobutyric Acid><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Max Brenner

FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, MANHASSET, NY

Good lead · 68/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$586,240
FY 2026

Project Title

Ghrelin as Radiation Countermeasure: Mechanism of Its Action

Grant Number:

5U01AI186997-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/5/2024

End Date:

11/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT DESCRIPTION: This U01 project aims to elucidate a novel neuroenteric mechanism through which ghrelin confers intestinal radioprotection, and to preclinically develop human ghrelin as a safe and effective mitigator for gastrointestinal acute radiation syndrome (GI-ARS). Ghrelin is a small pep...

Research Terms

<ACh Receptors><Acetylcholine Receptors><Acute Radiation Syndrome><Amino Acids><Animal Model><Animal Models and Related Studies><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Apoptosis><Apoptosis Pathway><Apoptotic><Attenuated><BBB crossing><Bacterial Translocation><Blood><Blood Reticuloendothelial System><Blood Serum><Body System><CNS Nervous System><Cell Body><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cells><Central Nervous System><Cholinergic Receptors><Cholinoceptive Sites><Cholinoceptors><Citrulline><Cranial Nerve X><Denervation><Dose><Dropsy><Dysfunction><Early-Stage Clinical Trials><Edema><Emergencies><Emergency Situation><Endotoxins><Enteric Nervous System><Enterocytes><Exposure to><FDA approved><Filgrastim SD-01><Functional disorder><GI Stem cell><Gene Expression><Gut Epithelial Permeability><Gut Hyperpermeability><Gut permeability><HG38><Histologic><Histologically><Human><Hydration><Hydration status><Hydrops><Individual><Inflammatory><Injury><Intestinal><Intestinal Epithelial Permeability><Intestinal Hyperpermeability><Intestinal permeability><Intestines><Ionizing Electromagnetic Radiation><Ionizing radiation><LGR5><LGR5 gene><Length><MAC393 antigen><Mediating><Mice><Mice Mammals><Miscellaneous Antibiotic><Modeling><Modern Man><Molecular><Murine><Mus><Neulasta><Neuranatomies><Neuranatomy><Neuraxis><Neuroanatomies><Neuroanatomy><Organ System><Organoids><PEG SD-01><PEG-rmetHuG-CSF><Pegfilgrastim><Peptides><Permeability><Pharmacology><Phase 1 Clinical Trials><Phase I Clinical Trials><Physiopathology><Pneumogastric Nerve><Progenitor Cells><Programmed Cell Death><Radiation><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation Protection><Radiation Toxicity><Radiation exposure><Radiation-Ionizing Total><Radioprotection><Radioprotective><Radiotoxicity><Recovery><Regulation><Reserve Cell><Rodent><Rodentia><Rodents Mammals><Role><SD-01><SD-01 sustained duration G-CSF><SGP-2 protein><SGP2><SP 40,40 protein><Safety><Sampling><Serum><Severities><Stomach><Subcutaneous Injections><Survival Rate><TRPM-2 protein><TRPM2><Tenth Cranial Nerve><Therapeutic><Total Body Irradiation><Vagotomy><Vagus Nerve><Vagus nerve structure><Villus><Whole-Body Irradiation><Whole-Body Radiation><X-ray-inducible protein 8><XIP8 protein><aminoacid><apoJ protein><apolipoprotein J><attenuate><attenuates><blood-brain barrier crossing><bloodbrain barrier crossing><bowel><bowel inflammation><cell sorting><cholinergic><cholinergic synapse><clusterin><complement lysis inhibitor><complement-associated protein SP-40,40 protein><effective therapy><effective treatment><gastric><gastrointestinal><gastrointestinal stem cell><ghrelin><gut inflammation><gut progenitor><gut stem cell><healing><improved><in vivo><inflamed bowel><inflamed gut><inflamed intestine><injuries><insight><intestinal crypt><intestinal epithelium><intestinal inflammation><intestinal progenitor><intestinal stem cells><ionizing output><ionizing radiation-induced protein-8><irradiation><irradiation injury><medical countermeasure><model of animal><mortality><novel><pathophysiology><phase I protocol><polyethylene glycol-conjugated filgrastim SD-01><pre-clinical><preclinical><progenitor cell expansion><progenitor expansion><protective effect><public health relevance><radiation countermeasure><radiation mitigation><radiation mitigator><radiation poisoning><radio-protection><radio-protective><radiological countermeasure><radiological mitigation><radiological mitigator><radiomitigation><radiomitigator><radioprotected><response><social role><standard of care><stem and progenitor cell expansion><stem cell expansion><stem cells><subdermal injection><sulfated glycoprotein 2><testosterone-repressed prostate message-2 protein><vagus nerve stimulation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Asha Varghese

FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, MANHASSET, NY

Good lead · 68/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$586,240
FY 2026

Project Title

Ghrelin as Radiation Countermeasure: Mechanism of Its Action

Grant Number:

5U01AI186997-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/5/2024

End Date:

11/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT DESCRIPTION: This U01 project aims to elucidate a novel neuroenteric mechanism through which ghrelin confers intestinal radioprotection, and to preclinically develop human ghrelin as a safe and effective mitigator for gastrointestinal acute radiation syndrome (GI-ARS). Ghrelin is a small pep...

Research Terms

<ACh Receptors><Acetylcholine Receptors><Acute Radiation Syndrome><Amino Acids><Animal Model><Animal Models and Related Studies><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Apoptosis><Apoptosis Pathway><Apoptotic><Attenuated><BBB crossing><Bacterial Translocation><Blood><Blood Reticuloendothelial System><Blood Serum><Body System><CNS Nervous System><Cell Body><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cells><Central Nervous System><Cholinergic Receptors><Cholinoceptive Sites><Cholinoceptors><Citrulline><Cranial Nerve X><Denervation><Dose><Dropsy><Dysfunction><Early-Stage Clinical Trials><Edema><Emergencies><Emergency Situation><Endotoxins><Enteric Nervous System><Enterocytes><Exposure to><FDA approved><Filgrastim SD-01><Functional disorder><GI Stem cell><Gene Expression><Gut Epithelial Permeability><Gut Hyperpermeability><Gut permeability><HG38><Histologic><Histologically><Human><Hydration><Hydration status><Hydrops><Individual><Inflammatory><Injury><Intestinal><Intestinal Epithelial Permeability><Intestinal Hyperpermeability><Intestinal permeability><Intestines><Ionizing Electromagnetic Radiation><Ionizing radiation><LGR5><LGR5 gene><Length><MAC393 antigen><Mediating><Mice><Mice Mammals><Miscellaneous Antibiotic><Modeling><Modern Man><Molecular><Murine><Mus><Neulasta><Neuranatomies><Neuranatomy><Neuraxis><Neuroanatomies><Neuroanatomy><Organ System><Organoids><PEG SD-01><PEG-rmetHuG-CSF><Pegfilgrastim><Peptides><Permeability><Pharmacology><Phase 1 Clinical Trials><Phase I Clinical Trials><Physiopathology><Pneumogastric Nerve><Progenitor Cells><Programmed Cell Death><Radiation><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation Protection><Radiation Toxicity><Radiation exposure><Radiation-Ionizing Total><Radioprotection><Radioprotective><Radiotoxicity><Recovery><Regulation><Reserve Cell><Rodent><Rodentia><Rodents Mammals><Role><SD-01><SD-01 sustained duration G-CSF><SGP-2 protein><SGP2><SP 40,40 protein><Safety><Sampling><Serum><Severities><Stomach><Subcutaneous Injections><Survival Rate><TRPM-2 protein><TRPM2><Tenth Cranial Nerve><Therapeutic><Total Body Irradiation><Vagotomy><Vagus Nerve><Vagus nerve structure><Villus><Whole-Body Irradiation><Whole-Body Radiation><X-ray-inducible protein 8><XIP8 protein><aminoacid><apoJ protein><apolipoprotein J><attenuate><attenuates><blood-brain barrier crossing><bloodbrain barrier crossing><bowel><bowel inflammation><cell sorting><cholinergic><cholinergic synapse><clusterin><complement lysis inhibitor><complement-associated protein SP-40,40 protein><effective therapy><effective treatment><gastric><gastrointestinal><gastrointestinal stem cell><ghrelin><gut inflammation><gut progenitor><gut stem cell><healing><improved><in vivo><inflamed bowel><inflamed gut><inflamed intestine><injuries><insight><intestinal crypt><intestinal epithelium><intestinal inflammation><intestinal progenitor><intestinal stem cells><ionizing output><ionizing radiation-induced protein-8><irradiation><irradiation injury><medical countermeasure><model of animal><mortality><novel><pathophysiology><phase I protocol><polyethylene glycol-conjugated filgrastim SD-01><pre-clinical><preclinical><progenitor cell expansion><progenitor expansion><protective effect><public health relevance><radiation countermeasure><radiation mitigation><radiation mitigator><radiation poisoning><radio-protection><radio-protective><radiological countermeasure><radiological mitigation><radiological mitigator><radiomitigation><radiomitigator><radioprotected><response><social role><standard of care><stem and progenitor cell expansion><stem cell expansion><stem cells><subdermal injection><sulfated glycoprotein 2><testosterone-repressed prostate message-2 protein><vagus nerve stimulation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PING WANG

FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, MANHASSET, NY

Good lead · 68/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$586,240
FY 2026

Project Title

Ghrelin as Radiation Countermeasure: Mechanism of Its Action

Grant Number:

5U01AI186997-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/5/2024

End Date:

11/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT DESCRIPTION: This U01 project aims to elucidate a novel neuroenteric mechanism through which ghrelin confers intestinal radioprotection, and to preclinically develop human ghrelin as a safe and effective mitigator for gastrointestinal acute radiation syndrome (GI-ARS). Ghrelin is a small pep...

Research Terms

<ACh Receptors><Acetylcholine Receptors><Acute Radiation Syndrome><Amino Acids><Animal Model><Animal Models and Related Studies><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Apoptosis><Apoptosis Pathway><Apoptotic><Attenuated><BBB crossing><Bacterial Translocation><Blood><Blood Reticuloendothelial System><Blood Serum><Body System><CNS Nervous System><Cell Body><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cells><Central Nervous System><Cholinergic Receptors><Cholinoceptive Sites><Cholinoceptors><Citrulline><Cranial Nerve X><Denervation><Dose><Dropsy><Dysfunction><Early-Stage Clinical Trials><Edema><Emergencies><Emergency Situation><Endotoxins><Enteric Nervous System><Enterocytes><Exposure to><FDA approved><Filgrastim SD-01><Functional disorder><GI Stem cell><Gene Expression><Gut Epithelial Permeability><Gut Hyperpermeability><Gut permeability><HG38><Histologic><Histologically><Human><Hydration><Hydration status><Hydrops><Individual><Inflammatory><Injury><Intestinal><Intestinal Epithelial Permeability><Intestinal Hyperpermeability><Intestinal permeability><Intestines><Ionizing Electromagnetic Radiation><Ionizing radiation><LGR5><LGR5 gene><Length><MAC393 antigen><Mediating><Mice><Mice Mammals><Miscellaneous Antibiotic><Modeling><Modern Man><Molecular><Murine><Mus><Neulasta><Neuranatomies><Neuranatomy><Neuraxis><Neuroanatomies><Neuroanatomy><Organ System><Organoids><PEG SD-01><PEG-rmetHuG-CSF><Pegfilgrastim><Peptides><Permeability><Pharmacology><Phase 1 Clinical Trials><Phase I Clinical Trials><Physiopathology><Pneumogastric Nerve><Progenitor Cells><Programmed Cell Death><Radiation><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation Protection><Radiation Toxicity><Radiation exposure><Radiation-Ionizing Total><Radioprotection><Radioprotective><Radiotoxicity><Recovery><Regulation><Reserve Cell><Rodent><Rodentia><Rodents Mammals><Role><SD-01><SD-01 sustained duration G-CSF><SGP-2 protein><SGP2><SP 40,40 protein><Safety><Sampling><Serum><Severities><Stomach><Subcutaneous Injections><Survival Rate><TRPM-2 protein><TRPM2><Tenth Cranial Nerve><Therapeutic><Total Body Irradiation><Vagotomy><Vagus Nerve><Vagus nerve structure><Villus><Whole-Body Irradiation><Whole-Body Radiation><X-ray-inducible protein 8><XIP8 protein><aminoacid><apoJ protein><apolipoprotein J><attenuate><attenuates><blood-brain barrier crossing><bloodbrain barrier crossing><bowel><bowel inflammation><cell sorting><cholinergic><cholinergic synapse><clusterin><complement lysis inhibitor><complement-associated protein SP-40,40 protein><effective therapy><effective treatment><gastric><gastrointestinal><gastrointestinal stem cell><ghrelin><gut inflammation><gut progenitor><gut stem cell><healing><improved><in vivo><inflamed bowel><inflamed gut><inflamed intestine><injuries><insight><intestinal crypt><intestinal epithelium><intestinal inflammation><intestinal progenitor><intestinal stem cells><ionizing output><ionizing radiation-induced protein-8><irradiation><irradiation injury><medical countermeasure><model of animal><mortality><novel><pathophysiology><phase I protocol><polyethylene glycol-conjugated filgrastim SD-01><pre-clinical><preclinical><progenitor cell expansion><progenitor expansion><protective effect><public health relevance><radiation countermeasure><radiation mitigation><radiation mitigator><radiation poisoning><radio-protection><radio-protective><radiological countermeasure><radiological mitigation><radiological mitigator><radiomitigation><radiomitigator><radioprotected><response><social role><standard of care><stem and progenitor cell expansion><stem cell expansion><stem cells><subdermal injection><sulfated glycoprotein 2><testosterone-repressed prostate message-2 protein><vagus nerve stimulation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael G Agadjanyan

INSTITUTE FOR MOLECULAR MEDICINE, HUNTINGTON BEACH, CA

Good lead · 66/100
Likely hiring
Large award
Active award
$2,115,510
FY 2026

Project Title

Safety/Tolerability/Immunogenicity of first-in-human Aβ DNA vaccine, AV-1959D Phase 1 trials in early-stage AD subjects: based on IND18953 cleared by FDA.

Grant Number:

5R01AG074983-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2022

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary Recent data from clinical trials with humanized or fully human mAbs targeting Aβ suggest that immunotherapy could clear/reduce brain amyloid plaques and even slow cognitive decline in vaccinated subjects when initiated as a preventive measure. However, passive immunotherapy with even...

Research Terms

<AD and related dementia><AD dementia><AD model><AD patients><AD prevention><AD related dementia><AD risk><AD risk factor><ADRD><AN-1792><AN1792><APOE><Ab response><Active Follow-up><Aducanumab><Adverse Experience><Adverse event><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer disease prevention><Alzheimer prevention><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's amyloid><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's patient><Alzheimers Dementia><Amyloid><Amyloid (Aβ) plaques><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid Substance><Amyloid beta-Protein><Amyloid β><Amyloid β oligomer><Amyloid β-Peptide><Amyloid β-Protein><Antibodies><Antibody Formation><Antibody Production><Antibody titer measurement><Antigenic Determinants><Apo-E><ApoE protein><Apolipoprotein E><Attenuated><Aβ><AβO><B blood cells><B cell><B cells><B-Cell Epitopes><B-Cells><B-Lymphocyte Epitopes><B-Lymphocytes><B-cell><BIIB037><Binding><Binding Determinants><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Serum><Brain><Brain Nervous System><Class II Genes><Clinical><Clinical Data><Clinical Treatment Moab><Clinical Trials><Clostridium tetani Toxin><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collecting Cell><Control Groups><Cooperative Agreements><DNA Vaccines><Data><Detection><Disease><Disorder><Disturbance in cognition><Domestic Rabbit><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><ELISA><ELISPOT><Early Intervention><Encephalon><Enzyme-Linked Immunosorbent Assay><Epitopes><Ethics><Future><Genetic Polymorphism><Goals><Grippe><Groups at risk><HBV disease><HLA Class II Genes><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><HepB><Hepatitis B><Hu-mABs><Human><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><Immune Interferon><Immune mediated therapy><Immune response><Immunize><Immunologically Directed Therapy><Immunotherapeutic agent><Immunotherapy><Impaired cognition><Inducer Cells><Inducer T-Lymphocytes><Inflammation><Influenza><Injections><Interferon Gamma><Interferon Type II><Laboratories><MHC Class II><MHC Class II Genes><Measures><Medical Inspection><Memory><Methods><Modern Man><Molecular Interaction><Monkeys><Monoclonal Antibodies><Naked DNA Vaccines><Neuritic Plaques><Nucleic Acids><Older Population><Oryctolagus cuniculus><PADRE 45><PADRE peptide><PBMC><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Passive Immunization><Passive Immunotherapy><Pathologic><Pathologic Processes><Pathological Processes><Pathology><Patients><People at risk><Peptides><Peripheral Blood Mononuclear Cell><Persons><Persons at risk><Phase><Phase I Study><Physical Examination><Placebo Control><Placebos><Populations at Risk><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Pre IND FDA meeting><Pre-IND mtg><Preparation><Preventative measure><Preventative treatment><Preventative vaccine><Preventive><Preventive measure><Preventive treatment><Preventive vaccine><Primary Senile Degenerative Dementia><Prophylactic vaccine><Publishing><Rabbits><Rabbits Mammals><Rad.-PET><Randomized><Recombinant DNA Vaccines><Recommendation><Reporting><Risk><Safety><Self Tolerance><Senile Plaques><Serum><Sham Treatment><Target Populations><Tau forming aggregates><Tauopathies><Test Result><Testing><Tetanus Toxin><Therapeutic><Time><U-Series Cooperative Agreements><Vaccinated><Vaccination><Vaccine Clinical Trial><Vaccinee><Vaccines><Viral Hepatitis B><a beta peptide><abeta><abeta oligomer><abnormally aggregated tau protein><active followup><active method><active technique><active treatment><aduhelm><aggregation in tau><alzheimer model><alzheimer risk><amyloid beta><amyloid beta oligomer><amyloid beta plaque><amyloid-b plaque><amyloid-b protein><antibody biosynthesis><antibody titering><attenuate><attenuates><autoimmune reactivity><autoreactivity><aβ oligomer><aβ plaques><beta amyloid fibril><bio-markers><biologic marker><biomarker><cognitive dysfunction><cognitive function><cognitive loss><cored plaque><cost><cost effective><design><designing><diffuse plaque><elderly patient><enzyme linked immunoassay><enzyme linked immunospot assay><ethical><evaluate vaccines><filamentous tau inclusion><first in man><first-in-human><follow up><follow-up><followed up><followup><hep B><hepatitis B virus disease><host response><humAbs><human mAbs><human monoclonal antibodies><human monoclonals><immune drugs><immune senescence><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapeutics><immune-based therapies><immune-based treatments><immuno therapy><immunogenic><immunogenicity><immunoglobulin biosynthesis><immunologic therapeutics><immunoresponse><immunosenescence><immunotherapeutics><immunotherapy agent><intervention arm><intravenous injection><lFN-Gamma><mAbs><manufacture><microtubule associated protein tau aggregation><microtubule associated protein tau deposit><monoclonal Abs><mouse model><multidisciplinary><murine model><neuropathologic tau><neuropathological tau><new marker><non-demented><nondemented><novel biomarker><novel marker><oAβ><older groups><older individuals><older patient><older person><oligomeric amyloid beta><oligomeric amyloid-β><paired helical filament of tau><pan HLA DR-binding epitope><passive immune therapy><passive immunotherapeutics><passive vaccination><patient living with Alzheimer's disease><patient population><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><peptide B><peptide M><peripheral blood><phase 1 study><phase 1 trial><phase I trial><physical examinations><placebo controlled><polymorphism><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><preparations><prevent><preventing><primary degenerative dementia><primary outcome><proenkephalin peptide B><programs><prophylactic><randomisation><randomization><randomly assigned><response><retinal S antigen peptide M><retinal peptide M18><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><safety testing><secondary outcome><self-aggregate tau><senile dementia of the Alzheimer type><sham therapy><soluble amyloid precursor protein><synthetic peptide><tau PHF><tau accumulation><tau aggregate><tau aggregation><tau associated neurodegeneration><tau associated neurodegenerative process><tau driven neurodegeneration><tau fibrillation><tau fibrillization><tau filament><tau inclusion><tau induced degeneration><tau induced neurodegeneration><tau mediated neurodegeneration><tau neurodegenerative disease><tau neurofibrillary tangle><tau neuropathology><tau oligomer><tau paired helical filament><tau pathology><tau pathophysiology><tau polymerization><tau protein accumulation><tau protein aggregation><tau proteinopathy><tau related neurodegeneration><tau-induced pathology><tau-tau interaction><tauopathic neurodegenerative disorder><tauopathy><treatment arm><vaccinated individual><vaccinated participant><vaccinated patient><vaccinated person><vaccinated subject><vaccination study><vaccination trial><vaccine evaluation><vaccine screening><vaccine strategy><vaccine study><vaccine testing><vaccine trial><τ aggregation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LON S SCHNEIDER

INSTITUTE FOR MOLECULAR MEDICINE, HUNTINGTON BEACH, CA

Good lead · 66/100
Likely hiring
Large award
Active award
$2,115,510
FY 2026

Project Title

Safety/Tolerability/Immunogenicity of first-in-human Aβ DNA vaccine, AV-1959D Phase 1 trials in early-stage AD subjects: based on IND18953 cleared by FDA.

Grant Number:

5R01AG074983-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2022

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary Recent data from clinical trials with humanized or fully human mAbs targeting Aβ suggest that immunotherapy could clear/reduce brain amyloid plaques and even slow cognitive decline in vaccinated subjects when initiated as a preventive measure. However, passive immunotherapy with even...

Research Terms

<AD and related dementia><AD dementia><AD model><AD patients><AD prevention><AD related dementia><AD risk><AD risk factor><ADRD><AN-1792><AN1792><APOE><Ab response><Active Follow-up><Aducanumab><Adverse Experience><Adverse event><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer disease prevention><Alzheimer prevention><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's amyloid><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's patient><Alzheimers Dementia><Amyloid><Amyloid (Aβ) plaques><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid Substance><Amyloid beta-Protein><Amyloid β><Amyloid β oligomer><Amyloid β-Peptide><Amyloid β-Protein><Antibodies><Antibody Formation><Antibody Production><Antibody titer measurement><Antigenic Determinants><Apo-E><ApoE protein><Apolipoprotein E><Attenuated><Aβ><AβO><B blood cells><B cell><B cells><B-Cell Epitopes><B-Cells><B-Lymphocyte Epitopes><B-Lymphocytes><B-cell><BIIB037><Binding><Binding Determinants><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Serum><Brain><Brain Nervous System><Class II Genes><Clinical><Clinical Data><Clinical Treatment Moab><Clinical Trials><Clostridium tetani Toxin><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collecting Cell><Control Groups><Cooperative Agreements><DNA Vaccines><Data><Detection><Disease><Disorder><Disturbance in cognition><Domestic Rabbit><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><ELISA><ELISPOT><Early Intervention><Encephalon><Enzyme-Linked Immunosorbent Assay><Epitopes><Ethics><Future><Genetic Polymorphism><Goals><Grippe><Groups at risk><HBV disease><HLA Class II Genes><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><HepB><Hepatitis B><Hu-mABs><Human><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><Immune Interferon><Immune mediated therapy><Immune response><Immunize><Immunologically Directed Therapy><Immunotherapeutic agent><Immunotherapy><Impaired cognition><Inducer Cells><Inducer T-Lymphocytes><Inflammation><Influenza><Injections><Interferon Gamma><Interferon Type II><Laboratories><MHC Class II><MHC Class II Genes><Measures><Medical Inspection><Memory><Methods><Modern Man><Molecular Interaction><Monkeys><Monoclonal Antibodies><Naked DNA Vaccines><Neuritic Plaques><Nucleic Acids><Older Population><Oryctolagus cuniculus><PADRE 45><PADRE peptide><PBMC><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Passive Immunization><Passive Immunotherapy><Pathologic><Pathologic Processes><Pathological Processes><Pathology><Patients><People at risk><Peptides><Peripheral Blood Mononuclear Cell><Persons><Persons at risk><Phase><Phase I Study><Physical Examination><Placebo Control><Placebos><Populations at Risk><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Pre IND FDA meeting><Pre-IND mtg><Preparation><Preventative measure><Preventative treatment><Preventative vaccine><Preventive><Preventive measure><Preventive treatment><Preventive vaccine><Primary Senile Degenerative Dementia><Prophylactic vaccine><Publishing><Rabbits><Rabbits Mammals><Rad.-PET><Randomized><Recombinant DNA Vaccines><Recommendation><Reporting><Risk><Safety><Self Tolerance><Senile Plaques><Serum><Sham Treatment><Target Populations><Tau forming aggregates><Tauopathies><Test Result><Testing><Tetanus Toxin><Therapeutic><Time><U-Series Cooperative Agreements><Vaccinated><Vaccination><Vaccine Clinical Trial><Vaccinee><Vaccines><Viral Hepatitis B><a beta peptide><abeta><abeta oligomer><abnormally aggregated tau protein><active followup><active method><active technique><active treatment><aduhelm><aggregation in tau><alzheimer model><alzheimer risk><amyloid beta><amyloid beta oligomer><amyloid beta plaque><amyloid-b plaque><amyloid-b protein><antibody biosynthesis><antibody titering><attenuate><attenuates><autoimmune reactivity><autoreactivity><aβ oligomer><aβ plaques><beta amyloid fibril><bio-markers><biologic marker><biomarker><cognitive dysfunction><cognitive function><cognitive loss><cored plaque><cost><cost effective><design><designing><diffuse plaque><elderly patient><enzyme linked immunoassay><enzyme linked immunospot assay><ethical><evaluate vaccines><filamentous tau inclusion><first in man><first-in-human><follow up><follow-up><followed up><followup><hep B><hepatitis B virus disease><host response><humAbs><human mAbs><human monoclonal antibodies><human monoclonals><immune drugs><immune senescence><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapeutics><immune-based therapies><immune-based treatments><immuno therapy><immunogenic><immunogenicity><immunoglobulin biosynthesis><immunologic therapeutics><immunoresponse><immunosenescence><immunotherapeutics><immunotherapy agent><intervention arm><intravenous injection><lFN-Gamma><mAbs><manufacture><microtubule associated protein tau aggregation><microtubule associated protein tau deposit><monoclonal Abs><mouse model><multidisciplinary><murine model><neuropathologic tau><neuropathological tau><new marker><non-demented><nondemented><novel biomarker><novel marker><oAβ><older groups><older individuals><older patient><older person><oligomeric amyloid beta><oligomeric amyloid-β><paired helical filament of tau><pan HLA DR-binding epitope><passive immune therapy><passive immunotherapeutics><passive vaccination><patient living with Alzheimer's disease><patient population><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><peptide B><peptide M><peripheral blood><phase 1 study><phase 1 trial><phase I trial><physical examinations><placebo controlled><polymorphism><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><preparations><prevent><preventing><primary degenerative dementia><primary outcome><proenkephalin peptide B><programs><prophylactic><randomisation><randomization><randomly assigned><response><retinal S antigen peptide M><retinal peptide M18><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><safety testing><secondary outcome><self-aggregate tau><senile dementia of the Alzheimer type><sham therapy><soluble amyloid precursor protein><synthetic peptide><tau PHF><tau accumulation><tau aggregate><tau aggregation><tau associated neurodegeneration><tau associated neurodegenerative process><tau driven neurodegeneration><tau fibrillation><tau fibrillization><tau filament><tau inclusion><tau induced degeneration><tau induced neurodegeneration><tau mediated neurodegeneration><tau neurodegenerative disease><tau neurofibrillary tangle><tau neuropathology><tau oligomer><tau paired helical filament><tau pathology><tau pathophysiology><tau polymerization><tau protein accumulation><tau protein aggregation><tau proteinopathy><tau related neurodegeneration><tau-induced pathology><tau-tau interaction><tauopathic neurodegenerative disorder><tauopathy><treatment arm><vaccinated individual><vaccinated participant><vaccinated patient><vaccinated person><vaccinated subject><vaccination study><vaccination trial><vaccine evaluation><vaccine screening><vaccine strategy><vaccine study><vaccine testing><vaccine trial><τ aggregation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Sultzer

INSTITUTE FOR MOLECULAR MEDICINE, HUNTINGTON BEACH, CA

Good lead · 66/100
Likely hiring
Large award
Active award
$2,115,510
FY 2026

Project Title

Safety/Tolerability/Immunogenicity of first-in-human Aβ DNA vaccine, AV-1959D Phase 1 trials in early-stage AD subjects: based on IND18953 cleared by FDA.

Grant Number:

5R01AG074983-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2022

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary Recent data from clinical trials with humanized or fully human mAbs targeting Aβ suggest that immunotherapy could clear/reduce brain amyloid plaques and even slow cognitive decline in vaccinated subjects when initiated as a preventive measure. However, passive immunotherapy with even...

Research Terms

<AD and related dementia><AD dementia><AD model><AD patients><AD prevention><AD related dementia><AD risk><AD risk factor><ADRD><AN-1792><AN1792><APOE><Ab response><Active Follow-up><Aducanumab><Adverse Experience><Adverse event><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer disease prevention><Alzheimer prevention><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's amyloid><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's patient><Alzheimers Dementia><Amyloid><Amyloid (Aβ) plaques><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Plaques><Amyloid Protein A4><Amyloid Substance><Amyloid beta-Protein><Amyloid β><Amyloid β oligomer><Amyloid β-Peptide><Amyloid β-Protein><Antibodies><Antibody Formation><Antibody Production><Antibody titer measurement><Antigenic Determinants><Apo-E><ApoE protein><Apolipoprotein E><Attenuated><Aβ><AβO><B blood cells><B cell><B cells><B-Cell Epitopes><B-Cells><B-Lymphocyte Epitopes><B-Lymphocytes><B-cell><BIIB037><Binding><Binding Determinants><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Serum><Brain><Brain Nervous System><Class II Genes><Clinical><Clinical Data><Clinical Treatment Moab><Clinical Trials><Clostridium tetani Toxin><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collecting Cell><Control Groups><Cooperative Agreements><DNA Vaccines><Data><Detection><Disease><Disorder><Disturbance in cognition><Domestic Rabbit><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><ELISA><ELISPOT><Early Intervention><Encephalon><Enzyme-Linked Immunosorbent Assay><Epitopes><Ethics><Future><Genetic Polymorphism><Goals><Grippe><Groups at risk><HBV disease><HLA Class II Genes><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><HepB><Hepatitis B><Hu-mABs><Human><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><Immune Interferon><Immune mediated therapy><Immune response><Immunize><Immunologically Directed Therapy><Immunotherapeutic agent><Immunotherapy><Impaired cognition><Inducer Cells><Inducer T-Lymphocytes><Inflammation><Influenza><Injections><Interferon Gamma><Interferon Type II><Laboratories><MHC Class II><MHC Class II Genes><Measures><Medical Inspection><Memory><Methods><Modern Man><Molecular Interaction><Monkeys><Monoclonal Antibodies><Naked DNA Vaccines><Neuritic Plaques><Nucleic Acids><Older Population><Oryctolagus cuniculus><PADRE 45><PADRE peptide><PBMC><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Passive Immunization><Passive Immunotherapy><Pathologic><Pathologic Processes><Pathological Processes><Pathology><Patients><People at risk><Peptides><Peripheral Blood Mononuclear Cell><Persons><Persons at risk><Phase><Phase I Study><Physical Examination><Placebo Control><Placebos><Populations at Risk><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Pre IND FDA meeting><Pre-IND mtg><Preparation><Preventative measure><Preventative treatment><Preventative vaccine><Preventive><Preventive measure><Preventive treatment><Preventive vaccine><Primary Senile Degenerative Dementia><Prophylactic vaccine><Publishing><Rabbits><Rabbits Mammals><Rad.-PET><Randomized><Recombinant DNA Vaccines><Recommendation><Reporting><Risk><Safety><Self Tolerance><Senile Plaques><Serum><Sham Treatment><Target Populations><Tau forming aggregates><Tauopathies><Test Result><Testing><Tetanus Toxin><Therapeutic><Time><U-Series Cooperative Agreements><Vaccinated><Vaccination><Vaccine Clinical Trial><Vaccinee><Vaccines><Viral Hepatitis B><a beta peptide><abeta><abeta oligomer><abnormally aggregated tau protein><active followup><active method><active technique><active treatment><aduhelm><aggregation in tau><alzheimer model><alzheimer risk><amyloid beta><amyloid beta oligomer><amyloid beta plaque><amyloid-b plaque><amyloid-b protein><antibody biosynthesis><antibody titering><attenuate><attenuates><autoimmune reactivity><autoreactivity><aβ oligomer><aβ plaques><beta amyloid fibril><bio-markers><biologic marker><biomarker><cognitive dysfunction><cognitive function><cognitive loss><cored plaque><cost><cost effective><design><designing><diffuse plaque><elderly patient><enzyme linked immunoassay><enzyme linked immunospot assay><ethical><evaluate vaccines><filamentous tau inclusion><first in man><first-in-human><follow up><follow-up><followed up><followup><hep B><hepatitis B virus disease><host response><humAbs><human mAbs><human monoclonal antibodies><human monoclonals><immune drugs><immune senescence><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapeutics><immune-based therapies><immune-based treatments><immuno therapy><immunogenic><immunogenicity><immunoglobulin biosynthesis><immunologic therapeutics><immunoresponse><immunosenescence><immunotherapeutics><immunotherapy agent><intervention arm><intravenous injection><lFN-Gamma><mAbs><manufacture><microtubule associated protein tau aggregation><microtubule associated protein tau deposit><monoclonal Abs><mouse model><multidisciplinary><murine model><neuropathologic tau><neuropathological tau><new marker><non-demented><nondemented><novel biomarker><novel marker><oAβ><older groups><older individuals><older patient><older person><oligomeric amyloid beta><oligomeric amyloid-β><paired helical filament of tau><pan HLA DR-binding epitope><passive immune therapy><passive immunotherapeutics><passive vaccination><patient living with Alzheimer's disease><patient population><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><peptide B><peptide M><peripheral blood><phase 1 study><phase 1 trial><phase I trial><physical examinations><placebo controlled><polymorphism><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><preparations><prevent><preventing><primary degenerative dementia><primary outcome><proenkephalin peptide B><programs><prophylactic><randomisation><randomization><randomly assigned><response><retinal S antigen peptide M><retinal peptide M18><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><safety testing><secondary outcome><self-aggregate tau><senile dementia of the Alzheimer type><sham therapy><soluble amyloid precursor protein><synthetic peptide><tau PHF><tau accumulation><tau aggregate><tau aggregation><tau associated neurodegeneration><tau associated neurodegenerative process><tau driven neurodegeneration><tau fibrillation><tau fibrillization><tau filament><tau inclusion><tau induced degeneration><tau induced neurodegeneration><tau mediated neurodegeneration><tau neurodegenerative disease><tau neurofibrillary tangle><tau neuropathology><tau oligomer><tau paired helical filament><tau pathology><tau pathophysiology><tau polymerization><tau protein accumulation><tau protein aggregation><tau proteinopathy><tau related neurodegeneration><tau-induced pathology><tau-tau interaction><tauopathic neurodegenerative disorder><tauopathy><treatment arm><vaccinated individual><vaccinated participant><vaccinated patient><vaccinated person><vaccinated subject><vaccination study><vaccination trial><vaccine evaluation><vaccine screening><vaccine strategy><vaccine study><vaccine testing><vaccine trial><τ aggregation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Evan Leaf

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 66/100
Likely hiring
Solid budget
Very recent
Active award
$312,324
FY 2026

Project Title

Pilot Randomized Clinical Trial of Glucocorticoid-Sparing Immunosuppressive Treatments for Immune Checkpoint Inhibitor-Associated AKI

Grant Number:

1R01DK144161-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/5/2026

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Immune checkpoint inhibitors (ICIs) are FDA-approved for >20 cancer types and have transformed the landscape of cancer treatment. However, the associated widespread T-cell activation can cause a broad range of immune-related adverse events, including acute kidney injury (ICI-AKI), wh...

Research Terms

<(TNF)-α><Accounting><Active Follow-up><Acute><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Adverse Experience><Adverse event><Antitumor Response><Attenuated><Autoimmune Diseases><Biological><Biopsy><Biopsy Sample><Biopsy Specimen><Blood Plasma><Blood Serum><CXCL9><CXCL9 gene><Cachectin><Cancer Center><Cancer Treatment><Cancers><Case Series><Case Study><Case-Base Studies><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Checkpoint inhibitor><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Treatment Moab><Clinical Trials><Colitis><Collaborations><Consensus><Creatinine><DF/HCC><Dana-Farber Cancer Institute><Data><Disease><Disorder><Disseminated Malignant Neoplasm><Dose><Dropout><Enrollment><Ensure><Evidence based treatment><FDA approved><Food and Drug Administration><Future><Glucocorticoids><Goals><Grant><Guidelines><Health Care><Hospitals><Humig><IRB><IRBs><Immune checkpoint inhibitor><Immunosuppressants><Immunosuppression><Immunosuppression Effect><Immunosuppressive Agents><Immunosuppressive Effect><Immunosuppressive drug><Immunosuppressive treatment><Infrastructure><Institutional Review Boards><Interruption><Interstitial Nephritis><Kidney><Kidney Urinary System><Life><MAb cA2><MIG Gene><Macrophage-Derived TNF><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Metastatic Cancer><Metastatic Malignant Neoplasm><Mission><Monoclonal Antibodies><Monocyte-Derived TNF><Myocarditis><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Nephrology><Paper><Participant><Patients><Plasma><Plasma Serum><Population><Procedures><Randomized><Recommendation><Recovery><Recurrence><Recurrent><Refractory><Remicade><Reticuloendothelial System, Serum, Plasma><SCYB9><Safety><Serious Adverse Event><Serum><Severe Adverse Event><Speed><Steroid Compound><Steroids><Subcellular Process><T-Cell Activation><T-Cells><T-Lymphocyte><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Testing><Time><Toxic effect><Toxicities><Treatment Failure><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><USFDA><United States Food and Drug Administration><Urine><activate T cells><active followup><acute kidney injury><adjudication><adjudicative process and procedure><anti-cancer therapy><anti-tumor response><attenuate><attenuates><autoimmune condition><autoimmune disorder><autoimmune toxicity><autoimmunity disease><biologic><cancer therapy><cancer type><cancer-directed therapy><cardiac inflammation><case report><check point immunotherapy><check point inhibitor therapy><check point inhibitory therapy><check point therapy><checkpoint immunotherapy><checkpoint inhibitor therapy><checkpoint inhibitory therapy><checkpoint therapy><chronic kidney disease><crg-10><cytokine><design><designing><develop therapy><enroll><experience><follow up><follow-up><followed up><followup><immune check point inhibitor><immune check point therapy><immune checkpoint therapy><immune suppression><immune suppressive activity><immune suppressive agent><immune suppressive function><immune suppressor><immune-mediated adverse events><immune-related adverse effect><immune-related adverse events><immune-related adverse reaction><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunosuppressive substance><immunosuppressor><improved><indexing><infliximab><inhibiting antibody><intervention arm><intervention development><kidney biopsy><mAbs><malignancy><monoclonal Abs><monoclonal antibody cA2><multidisciplinary><neoplasm/cancer><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><oncology trial><open label><open label study><pilot trial><primary outcome><randomisation><randomization><randomized, clinical trials><randomly assigned><recruit><renal><renal biopsy><response><response to therapy><response to treatment><secondary outcome><serious adverse experience><serious adverse reaction><side effect><standard of care><therapeutic response><therapy development><therapy failure><therapy response><thymus derived lymphocyte><treatment arm><treatment development><treatment response><treatment responsiveness><treatment strategy><trial comparing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Meghan E. Sise

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 66/100
Likely hiring
Solid budget
Very recent
Active award
$312,324
FY 2026

Project Title

Pilot Randomized Clinical Trial of Glucocorticoid-Sparing Immunosuppressive Treatments for Immune Checkpoint Inhibitor-Associated AKI

Grant Number:

1R01DK144161-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/5/2026

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Immune checkpoint inhibitors (ICIs) are FDA-approved for >20 cancer types and have transformed the landscape of cancer treatment. However, the associated widespread T-cell activation can cause a broad range of immune-related adverse events, including acute kidney injury (ICI-AKI), wh...

Research Terms

<(TNF)-α><Accounting><Active Follow-up><Acute><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Adverse Experience><Adverse event><Antitumor Response><Attenuated><Autoimmune Diseases><Biological><Biopsy><Biopsy Sample><Biopsy Specimen><Blood Plasma><Blood Serum><CXCL9><CXCL9 gene><Cachectin><Cancer Center><Cancer Treatment><Cancers><Case Series><Case Study><Case-Base Studies><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Checkpoint inhibitor><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Treatment Moab><Clinical Trials><Colitis><Collaborations><Consensus><Creatinine><DF/HCC><Dana-Farber Cancer Institute><Data><Disease><Disorder><Disseminated Malignant Neoplasm><Dose><Dropout><Enrollment><Ensure><Evidence based treatment><FDA approved><Food and Drug Administration><Future><Glucocorticoids><Goals><Grant><Guidelines><Health Care><Hospitals><Humig><IRB><IRBs><Immune checkpoint inhibitor><Immunosuppressants><Immunosuppression><Immunosuppression Effect><Immunosuppressive Agents><Immunosuppressive Effect><Immunosuppressive drug><Immunosuppressive treatment><Infrastructure><Institutional Review Boards><Interruption><Interstitial Nephritis><Kidney><Kidney Urinary System><Life><MAb cA2><MIG Gene><Macrophage-Derived TNF><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Metastatic Cancer><Metastatic Malignant Neoplasm><Mission><Monoclonal Antibodies><Monocyte-Derived TNF><Myocarditis><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Nephrology><Paper><Participant><Patients><Plasma><Plasma Serum><Population><Procedures><Randomized><Recommendation><Recovery><Recurrence><Recurrent><Refractory><Remicade><Reticuloendothelial System, Serum, Plasma><SCYB9><Safety><Serious Adverse Event><Serum><Severe Adverse Event><Speed><Steroid Compound><Steroids><Subcellular Process><T-Cell Activation><T-Cells><T-Lymphocyte><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Testing><Time><Toxic effect><Toxicities><Treatment Failure><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><USFDA><United States Food and Drug Administration><Urine><activate T cells><active followup><acute kidney injury><adjudication><adjudicative process and procedure><anti-cancer therapy><anti-tumor response><attenuate><attenuates><autoimmune condition><autoimmune disorder><autoimmune toxicity><autoimmunity disease><biologic><cancer therapy><cancer type><cancer-directed therapy><cardiac inflammation><case report><check point immunotherapy><check point inhibitor therapy><check point inhibitory therapy><check point therapy><checkpoint immunotherapy><checkpoint inhibitor therapy><checkpoint inhibitory therapy><checkpoint therapy><chronic kidney disease><crg-10><cytokine><design><designing><develop therapy><enroll><experience><follow up><follow-up><followed up><followup><immune check point inhibitor><immune check point therapy><immune checkpoint therapy><immune suppression><immune suppressive activity><immune suppressive agent><immune suppressive function><immune suppressor><immune-mediated adverse events><immune-related adverse effect><immune-related adverse events><immune-related adverse reaction><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunosuppressive substance><immunosuppressor><improved><indexing><infliximab><inhibiting antibody><intervention arm><intervention development><kidney biopsy><mAbs><malignancy><monoclonal Abs><monoclonal antibody cA2><multidisciplinary><neoplasm/cancer><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><oncology trial><open label><open label study><pilot trial><primary outcome><randomisation><randomization><randomized, clinical trials><randomly assigned><recruit><renal><renal biopsy><response><response to therapy><response to treatment><secondary outcome><serious adverse experience><serious adverse reaction><side effect><standard of care><therapeutic response><therapy development><therapy failure><therapy response><thymus derived lymphocyte><treatment arm><treatment development><treatment response><treatment responsiveness><treatment strategy><trial comparing>
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Martha Skiles

WASHINGTON STATE DEPARTMENT OF HEALTH, TUMWATER, WA

Good lead · 64/100
Likely hiring
Very recent
Active award
Team-scale grant
$175,000
FY 2025

Project Title

RFA-DP-22-001 DP006601 Component A - Core Surveillance - Washington Pregnancy Risk Assessment Monitoring System (PRAMS) RFA-DP-16-001

Grant Number:

6U01DP006601-05M002

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

ALLCDC

Start Date:

5/1/2021

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Washington State PRAMS Core Grant –Component A Project Summary/Abstract PRAMS 2021 Grant Project Title: Pregnancy Risk Assessment Monitoring System (PRAMS) (U01) Category B. (Existing States) Washington State PRAMS 2021 Project Director: Teresa Vollan, PI/PD Address: Washington State Department of H...

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Sarah Lyn Karalunas

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Good lead · 62/100
Large award
Very recent
Active award
Team-scale grant
$9,762,321
FY 2026

Project Title

Person-centered diagnostics and prediction for child dysregulatory psychopathology using novel phenotypes

Grant Number:

4UF1MH135970-03

Activity Code:

UF1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary This U01 proposal is submitted in response to the NIMH IMPACT RFA (RFA-MH-23-105). It will extend research efforts to both define novel, deployable behavioral phenotypes (highlighting cognitive and emotional transdiagnostic measures) and develop and test diagnostic and prognostic pre...

Research Terms

<0-11 years old><7 year old><7 years of age><AD/HD><ADHD><Accuracy of Diagnosis><Active Follow-up><Address><Affect><Affective Disorders><Algorithms><Anxiety Disorders><Arousal><Attention><Attention deficit hyperactivity disorder><Behavior><Behavioral><Caring><Child><Child Youth><Childhood><Children (0-21)><Classification><Clinic><Clinical><Clinical Evaluation><Clinical Testing><Cognition><Cognitive><Complex><Computational algorithm><Computer Models><Computerized Medical Record><Computerized Models><Connectionist Models><Country><Data><Data Collection><Data Sources><Deterioration><Diagnosis><Diagnostic><Diagnostic tests><Dimensions><Disruptive Behavior Disorder><ED visit><ER visit><Effectiveness><Electronic Medical Record><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Emotional><Emotions><Evaluation><Face><Goals><Hand><Harvest><Impairment><Laboratories><Learning><Location><Logic><Measures><Mental Health><Mental Hygiene><Methods><Modeling><Mood Disorders><NIMH><National Institute of Mental Health><Negative Valence><Neural Network Models><Neural Network Simulation><Oregon><Outcome><Patient Recruitments><Patients><Perceptrons><Persons><Phenotype><Population><Position><Positioning Attribute><Positive Valence><Predominantly Hyperactive-Impulsive Type Attention-Deficit Disorder><Predominantly Hyperactive-Impulsive Type Hyperactivity Disorder><Preparedness><Problem behavior><Psychiatry><Psychological Health><Psychopathology><Readiness><Records><Recruitment Activity><Reproducibility><Research><Research Resources><Resources><Role><Savings><Site><Symptoms><Systematics><Testing><Time><Underrepresented Groups><Underrepresented Populations><Underserved Population><Work><Youth><Youth 10-21><abnormal psychology><active followup><active recruitment><advanced analytics><age 7><age 7 years><alertness><behavior measurement><behavior phenotype><behavioral measure><behavioral measurement><behavioral phenotyping><behavioral problem><clinical care><clinical diagnostics><clinical predictors><clinical prognostic><clinical test><cohort investigation><cohort research><computational modeling><computational models><computer algorithm><computer based models><computer based prediction><computerized modeling><cost><diagnosis standard><diagnostic ability><diagnostic accuracy><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disruptive behavioral disorder><emotion dysregulation><emotion regulation><emotional dysregulation><emotional regulation><executive control><executive function><faces><facial><follow up><follow-up><followed up><followup><hands><high risk><improved><indexing><informant><innovate><innovation><innovative><investigate cohort><investigate longitudinal><investigate prospective><kids><longitudinal investigation><longitudinal research><machine learning based model><machine learning model><medical diagnostic><new diagnostics><next generation diagnostics><novel><novel diagnostics><outcome prediction><participant recruitment><patient population><pediatric><person centered><prediction algorithm><predictive modeling><prognostic><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><prospective investigation><prospective research><prospective test><research clinical testing><response><service utilization><seven year old><seven years of age><social role><study cohort><study longitudinal><study prospective><substance use><substance using><suicidal><suicidality><survey cohort><survey longitudinal><survey prospective><trait><transfer learning><under representation of groups><under represented groups><under represented people><under represented populations><under served group><under served individual><under served people><under served population><underrepresentation of groups><underrepresented people><underserved group><underserved individual><underserved people><youngster><youth age>
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Bonnie J. Nagel

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Good lead · 62/100
Large award
Very recent
Active award
Team-scale grant
$9,762,321
FY 2026

Project Title

Person-centered diagnostics and prediction for child dysregulatory psychopathology using novel phenotypes

Grant Number:

4UF1MH135970-03

Activity Code:

UF1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary This U01 proposal is submitted in response to the NIMH IMPACT RFA (RFA-MH-23-105). It will extend research efforts to both define novel, deployable behavioral phenotypes (highlighting cognitive and emotional transdiagnostic measures) and develop and test diagnostic and prognostic pre...

Research Terms

<0-11 years old><7 year old><7 years of age><AD/HD><ADHD><Accuracy of Diagnosis><Active Follow-up><Address><Affect><Affective Disorders><Algorithms><Anxiety Disorders><Arousal><Attention><Attention deficit hyperactivity disorder><Behavior><Behavioral><Caring><Child><Child Youth><Childhood><Children (0-21)><Classification><Clinic><Clinical><Clinical Evaluation><Clinical Testing><Cognition><Cognitive><Complex><Computational algorithm><Computer Models><Computerized Medical Record><Computerized Models><Connectionist Models><Country><Data><Data Collection><Data Sources><Deterioration><Diagnosis><Diagnostic><Diagnostic tests><Dimensions><Disruptive Behavior Disorder><ED visit><ER visit><Effectiveness><Electronic Medical Record><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Emotional><Emotions><Evaluation><Face><Goals><Hand><Harvest><Impairment><Laboratories><Learning><Location><Logic><Measures><Mental Health><Mental Hygiene><Methods><Modeling><Mood Disorders><NIMH><National Institute of Mental Health><Negative Valence><Neural Network Models><Neural Network Simulation><Oregon><Outcome><Patient Recruitments><Patients><Perceptrons><Persons><Phenotype><Population><Position><Positioning Attribute><Positive Valence><Predominantly Hyperactive-Impulsive Type Attention-Deficit Disorder><Predominantly Hyperactive-Impulsive Type Hyperactivity Disorder><Preparedness><Problem behavior><Psychiatry><Psychological Health><Psychopathology><Readiness><Records><Recruitment Activity><Reproducibility><Research><Research Resources><Resources><Role><Savings><Site><Symptoms><Systematics><Testing><Time><Underrepresented Groups><Underrepresented Populations><Underserved Population><Work><Youth><Youth 10-21><abnormal psychology><active followup><active recruitment><advanced analytics><age 7><age 7 years><alertness><behavior measurement><behavior phenotype><behavioral measure><behavioral measurement><behavioral phenotyping><behavioral problem><clinical care><clinical diagnostics><clinical predictors><clinical prognostic><clinical test><cohort investigation><cohort research><computational modeling><computational models><computer algorithm><computer based models><computer based prediction><computerized modeling><cost><diagnosis standard><diagnostic ability><diagnostic accuracy><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disruptive behavioral disorder><emotion dysregulation><emotion regulation><emotional dysregulation><emotional regulation><executive control><executive function><faces><facial><follow up><follow-up><followed up><followup><hands><high risk><improved><indexing><informant><innovate><innovation><innovative><investigate cohort><investigate longitudinal><investigate prospective><kids><longitudinal investigation><longitudinal research><machine learning based model><machine learning model><medical diagnostic><new diagnostics><next generation diagnostics><novel><novel diagnostics><outcome prediction><participant recruitment><patient population><pediatric><person centered><prediction algorithm><predictive modeling><prognostic><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><prospective investigation><prospective research><prospective test><research clinical testing><response><service utilization><seven year old><seven years of age><social role><study cohort><study longitudinal><study prospective><substance use><substance using><suicidal><suicidality><survey cohort><survey longitudinal><survey prospective><trait><transfer learning><under representation of groups><under represented groups><under represented people><under represented populations><under served group><under served individual><under served people><under served population><underrepresentation of groups><underrepresented people><underserved group><underserved individual><underserved people><youngster><youth age>
View Full Project Details on NIH Reporter
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Franco Pestilli

UNIVERSITY OF TEXAS AT AUSTIN, AUSTIN, TX

Good lead · 62/100
Large award
Very recent
Active award
Team-scale grant
$1,069,855
FY 2026

Project Title

BRAIN CONNECTS: The Axonal Projectome EXchange (APEX)

Grant Number:

5U24NS140384-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/21/2025

End Date:

12/31/2029

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary The brain is the most complex organ in the human body. Millions of interconnected cells communicate through an intricate network of pathways to give rise to our cognition, perception, and emotional experiences. At present we lack an accurate and complete map of the axonal projections...

Research Terms

<Atlases><Axon><BRAIN initiative><Benchmarking><Best Practice Analysis><Brain><Brain Nervous System><Brain Research through Advancing Innovative Neurotechnologies initiative><Callithrix><Cell Body><Cell Communication><Cell Interaction><Cell-to-Cell Interaction><Cells><Censuses><Clinical><Cognition><Collaborations><Communication><Communities><Comparative Study><Complex><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Analyses><Data Analysis><Data Analytics><Data Coordinating Center><Data Coordination Center><Dedications><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Disease><Disorder><Encephalon><Ensure><Fostering><Foundations><Funding><General Population><General Public><Goals><Hapale><Health><Human><Human Figure><Human body><Image><Individual><Internet><Investigators><Link><Macaca><Macaque><Maps><Marmosets><Mental disorders><Mental health disorders><Methods><Mice><Mice Mammals><Microscopy><Modality><Modern Man><Multimodal Imaging><Murine><Mus><Nervous System Diseases><Nervous System Disorder><Neurologic Disorders><Neurological Disorders><Neurosciences><Newsletter><Optics><Organ><Pathway interactions><Perception><Performance><Phase><Position><Positioning Attribute><Primates><Primates Mammals><Process><Psychiatric Disease><Psychiatric Disorder><Research><Research Activity><Research Personnel><Research Resources><Researchers><Resolution><Resources><Series><Short-Tusked Marmoset><Techniques><Technology><Time><Visualization><WWW><Work><X ray microscopy><Xray microscopy><analytical tool><benchmark><brain based><cell type><clinical applicability><clinical application><cloud based><cost effective><dMRI><data acquisition><data acquisitions><data analysis pipeline><data archive><data archives><data diversity><data exchange><data harmonization><data integration><data interpretation><data processing pipeline><data quality><data tools><data transfer><data transmission><diffusion tensor imaging><diverse data><emotional experience><harmonized data><high definition><high-resolution><image-based method><imaging><imaging method><imaging modality><interoperability><knowledge base><lectures><light microscopy><meeting><meetings><mental illness><multi-modal imaging><multi-modality><multi-modality imaging><multi-scale data><multimodality><multimodality imaging><multiscale data><neural circuit><neural circuitry><neural control><neural imaging><neural regulation><neuro-imaging><neurocircuitry><neuroimaging><neurological disease><neurological imaging><neuromodulation><neuromodulatory><neuroregulation><neurosurgery><new technology><novel><novel technologies><optical><outreach><pathway><programs><psychiatric illness><psychological disorder><resolutions><response><scale up><social media><synaptic circuit><synaptic circuitry><technological innovation><tool><web><work group><working group><world wide web>
View Full Project Details on NIH Reporter
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Anastasia Yendiki

UNIVERSITY OF TEXAS AT AUSTIN, AUSTIN, TX

Good lead · 62/100
Large award
Very recent
Active award
Team-scale grant
$1,069,855
FY 2026

Project Title

BRAIN CONNECTS: The Axonal Projectome EXchange (APEX)

Grant Number:

5U24NS140384-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/21/2025

End Date:

12/31/2029

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary The brain is the most complex organ in the human body. Millions of interconnected cells communicate through an intricate network of pathways to give rise to our cognition, perception, and emotional experiences. At present we lack an accurate and complete map of the axonal projections...

Research Terms

<Atlases><Axon><BRAIN initiative><Benchmarking><Best Practice Analysis><Brain><Brain Nervous System><Brain Research through Advancing Innovative Neurotechnologies initiative><Callithrix><Cell Body><Cell Communication><Cell Interaction><Cell-to-Cell Interaction><Cells><Censuses><Clinical><Cognition><Collaborations><Communication><Communities><Comparative Study><Complex><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Analyses><Data Analysis><Data Analytics><Data Coordinating Center><Data Coordination Center><Dedications><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Disease><Disorder><Encephalon><Ensure><Fostering><Foundations><Funding><General Population><General Public><Goals><Hapale><Health><Human><Human Figure><Human body><Image><Individual><Internet><Investigators><Link><Macaca><Macaque><Maps><Marmosets><Mental disorders><Mental health disorders><Methods><Mice><Mice Mammals><Microscopy><Modality><Modern Man><Multimodal Imaging><Murine><Mus><Nervous System Diseases><Nervous System Disorder><Neurologic Disorders><Neurological Disorders><Neurosciences><Newsletter><Optics><Organ><Pathway interactions><Perception><Performance><Phase><Position><Positioning Attribute><Primates><Primates Mammals><Process><Psychiatric Disease><Psychiatric Disorder><Research><Research Activity><Research Personnel><Research Resources><Researchers><Resolution><Resources><Series><Short-Tusked Marmoset><Techniques><Technology><Time><Visualization><WWW><Work><X ray microscopy><Xray microscopy><analytical tool><benchmark><brain based><cell type><clinical applicability><clinical application><cloud based><cost effective><dMRI><data acquisition><data acquisitions><data analysis pipeline><data archive><data archives><data diversity><data exchange><data harmonization><data integration><data interpretation><data processing pipeline><data quality><data tools><data transfer><data transmission><diffusion tensor imaging><diverse data><emotional experience><harmonized data><high definition><high-resolution><image-based method><imaging><imaging method><imaging modality><interoperability><knowledge base><lectures><light microscopy><meeting><meetings><mental illness><multi-modal imaging><multi-modality><multi-modality imaging><multi-scale data><multimodality><multimodality imaging><multiscale data><neural circuit><neural circuitry><neural control><neural imaging><neural regulation><neuro-imaging><neurocircuitry><neuroimaging><neurological disease><neurological imaging><neuromodulation><neuromodulatory><neuroregulation><neurosurgery><new technology><novel><novel technologies><optical><outreach><pathway><programs><psychiatric illness><psychological disorder><resolutions><response><scale up><social media><synaptic circuit><synaptic circuitry><technological innovation><tool><web><work group><working group><world wide web>
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Jae U Jung

CLEVELAND CLINIC LERNER COM-CWRU, CLEVELAND, OH

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$972,133
FY 2025

Project Title

Development of three KSHV vaccine platforms and chimeric MHV68-K-G for in vivo mouse infection study

Grant Number:

5U01CA294881-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Abstract Kaposi's sarcoma-associated herpesvirus (KSHV) is a prevalent virus that establishes a lifelong persistent infection in humans and is associated with Kaposi's sarcoma (KS) and primary effusion lymphomas (PELs). Despite the reduction in complications associated with HIV infection due to comb...

Research Terms

<AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Adverse effects><Affect><Africa South of the Sahara><Animal Model><Animal Models and Related Studies><Antibody Response><Antigens><Area><Attention><BAC clone><BACs><Bacterial Artificial Chromosomes><Basic Research><Basic Science><Codon><Codon Nucleotides><Development><Disease><Disorder><Engineering><Epidemic Parotitis Virus><Exhibits><Generations><Genes><Genetic><Glycoproteins><Goals><HHV-8><HHV8><HIV><HIV Infections><HTLV-III Infections><HTLV-III-LAV Infections><Health><Herpes infection><Herpesviridae><Herpesviridae Infections><Herpesviridae disease><Herpesvirus Infections><Herpesvirus Vaccines><Herpesviruses><Human><Human Herpesvirus 8><Human Immunodeficiency Viruses><Human T-Lymphotropic Virus Type III Infections><Iatrogenic Kaposi's Sarcoma><Immune response><Immunity><Immunocompromised><Immunocompromised Host><Immunocompromised Patient><Immunosuppressed Host><In Vitro><Individual><Infection><KSHV><Kaposi Sarcoma><Kaposi Sarcoma-Associated Herpes Virus><Kaposi Sarcoma-Associated Herpesvirus><Kaposi sarcoma associated virus><Kaposi sarcoma herpes virus><Kaposi's Sarcoma><Kaposi's sarcoma (KS)-associated herpesvirus><LAV-HTLV-III><Link><Long-term infection><Lymphadenopathy-Associated Virus><Measles virus><Measures><Messenger RNA><Mice><Mice Mammals><Modeling><Modern Man><Mouse herpesvirus strain 68><Multiple Hemorrhagic Sarcoma><Mumps virus><Murid herpesvirus 4><Murine><Murine herpesvirus 68><Mus><Myxovirus parotitidis><Play><Population><Preventive><Process><Production><Protein Subunits><Proteins><RNA vaccine><RNA-based vaccine><Recombinants><Research><Research Resources><Resources><Role><Safety><Side><Sub-Saharan Africa><Subsaharan Africa><Subunit Vaccines><Technology><Testing><Transplant Recipients><UTRs><Untranslated Regions><Vaccinated><Vaccine Antigen><Vaccine Design><Vaccines><Variant><Variation><Viral><Viral Diseases><Viral Pathogenesis><Viral Vector><Virus><Virus Diseases><Virus Replication><Virus-HHV8><Virus-HIV><Vulnerable Populations><antiretroviral therapy><antiretroviral treatment><assess effectiveness><chronic infection><determine effectiveness><develop a vaccine><develop vaccines><development of a vaccine><developmental><effectiveness assessment><effectiveness evaluation><efficacy testing><evaluate effectiveness><examine effectiveness><experience><flexibility><flexible><health services infrastructure><health system infrastructure><healthcare delivery infrastructure><healthcare infrastructure><healthcare system infrastructure><herpes virus><high risk><host response><immune system response><immunogen><immunogenicity><immunoresponse><immunosuppressed patient><in vivo><in vivo Model><interest><kaposi's sarcoma herpesvirus><kaposi's sarcoma-associated human herpesvirus><lipid based nanoparticle><lipid nanoparticle><mRNA><mRNA lipid nano particle vaccine><mRNA vaccine><mRNA-LNP based vaccine><mRNA-LNP combination vaccines><mRNA-LNP vaccines><mRNA-based vaccine><model of animal><mouse model><murine model><nano particle><nano-sized particle><nanoparticle><nanosized particle><neutralizing antibody><new vaccines><next generation vaccines><novel><novel vaccines><older men><persistent infection><plasmid vaccine><primary effusion lymphoma><recombinant virus><rougeole virus><rubeola virus><self assembly><social role><tool><transplant patient><vaccine candidate><vaccine development><vaccine efficacy><vaccine platform><vector vaccine><vector-based vaccine><viral infection><viral multiplication><viral replication><viral testing><virus infection><virus multiplication><virus pathogenesis><virus testing><virus-induced disease><vulnerable group><vulnerable individual><vulnerable people>
View Full Project Details on NIH Reporter
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John H Adams

UNIVERSITY OF SOUTH FLORIDA, TAMPA, FL

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$882,985
FY 2025

Project Title

Accelerating discovery of an efficacious Plasmodium vivax multivalent multi-stage vaccine

Grant Number:

5U01AI155361-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2020

End Date:

11/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract Plasmodium vivax is the second leading cause of malaria and the most prevalent cause of malaria outside of Africa. The estimated cost of the global burden of vivax malaria is $1.4 - $4 billion per year and more people live at risk worldwide from P. vivax than P. falciparum. ...

Research Terms

<21+ years old><Acceleration><Adjuvant><Adult><Adult Human><Africa><Aliquot><Animals><Antibodies><Antibody Response><Antibody titer measurement><Antigen Targeting><Antigen-Presenting Cells><Antigenic Determinants><Antigens><Antisera><Assay><Binding><Binding Determinants><Binding Proteins><Bioassay><Biological Assay><Blood><Blood Reticuloendothelial System><Blood erythrocyte><Burma><Cell Body><Cells><Clinical><Clinical Treatment Moab><Collaborations><Country><Cryofixation><Cryopreservation><Culicidae><Development><Ensure><Epitope Mapping><Epitopes><Erythrocytes><Erythrocytic><Formulation><Future><Generalized Growth><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Goals><Growth><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><Human><Immune><Immune Sera><Immune response><Immunes><Immunity><Immunization><Immunize><Immunoassay><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><In Vitro><Individual><Infection><Infection prevention><Laboratories><Laboratory Animals><Ligand Binding Protein><Ligand Binding Protein Gene><Limited Stage><Liver><Liver Cells><Malaria><Malaria Vaccines><Malarial Vaccines><Maps><Marrow erythrocyte><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular Interaction><Monoclonal Antibodies><Mosquitoes><Murine><Mus><Myanmar><Nature><Non-Polyadenylated RNA><P falciparum><P vivax><P. falciparum><P. vivax><P.falciparum><Paludism><Parasites><Parasitic infection><Persons><Peru><Plasmodium Infections><Plasmodium falciparum><Plasmodium vivax><Plasmodium vivax Malaria><Post-vaccination infection><Prevent infection><Process><Productivity><Property><Protein Binding><RNA><RNA Gene Products><RNA vaccine><RNA-based vaccine><Recombinants><Red Blood Cells><Red Cell><Relapse><Ribonucleic Acid><Risk><Seasons><Source><Sporozoites><Subunit Vaccines><Thailand><Tissue Growth><Transgenic Organisms><Transmission><Vaccination><Vaccine Antigen><Vaccine Design><Vaccines><Validation><Vivax Malaria><Work><accessory cell><adulthood><affordable healthcare><antibody titering><blood corpuscles><bound protein><breakthrough infection><candidate validation><cell type><cold preservation><cold storage><cost estimate><cost estimation><deliver vaccines><design><designing><develop a vaccine><develop vaccines><development of a vaccine><developmental><experiment><experimental research><experimental study><experiments><geographic site><global health><hepatic body system><hepatic organ system><host response><immune serum><immune system response><immunogen><immunogenicity><immunoreactivity><immunoresponse><in vitro Assay><infected with parasites><mAbs><mRNA vaccine><mRNA-based vaccine><migration><monoclonal Abs><nano particle><nano-sized particle><nanoparticle><nanosized particle><ontogeny><parasite infection><prevent><preventing><protective efficacy><transgenic><transmission process><transmission-blocking vaccine><uptake><vaccine candidate><vaccine delivery><vaccine development><vaccine strategy><vaccines against malaria><vaccinology><validations>
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Fatemeh Momen Heravi

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$816,981
FY 2025

Project Title

Immune and transcriptomic biomarkers of progressive oral premalignant lesions

Grant Number:

5U01DE033351-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2024

End Date:

8/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Oral squamous cell carcinoma (OSCC) is the 6th leading cause of cancer-related mortality worldwide. OSCC is curable with favorable survival outcomes if detected early. The majority of OSCCs are preceded by oral potentially malignant disorders (OPMDs) with oral leukoplakia or white le...

Research Terms

<Active Follow-up><Address><Alcohol Chemical Class><Alcohols><Biological Markers><Body Tissues><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cancer Cause><Cancer Etiology><Cancers><Causality><Cell Body><Cells><Cessation of life><Characteristics><Clinical><Clinical Markers><Code><Coding System><Communities><Data><Data Set><Death><Development><Diagnosis><Disease><Disorder><Early Diagnosis><Early identification><Etiology><Fluorescence><Functional RNA><Gene Combinations><Gene Expression><HPV><HPV [-]><HPV associated mouth cancer><HPV associated oral cancer><HPV associated oral malignancies><HPV induced Oral Cancer><HPV infection-associated oral cancer><HPV negative><HPV positive><HPV related cancer of the mouth><HPV related oral cancer><HPV related oral malignancies><HPV(+)><HPV(-)><HPV+><HPV+ oral cancer><HPV-High Risk><Heterogeneity><High Risk Oncogenic HPV><High risk HPV><High risk Human Papillomavirus><High risk Human papilloma virus><Histologic><Histologic Grade><Histologically><Histopathologic Grade><Human Papilloma Virus><Human Papillomavirus><Immune><Immune Markers><Immune mediated therapy><Immunes><Immunologic Markers><Immunologically Directed Therapy><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><Incidence><Individual><Infectious Human Wart Virus><Keratotic Plaque><Knowledge><Lesion><Leukoplakia><Machine Learning><Malignant><Malignant - descriptor><Malignant Conversion><Malignant Neoplasms><Malignant Oral Cavity Neoplasm><Malignant Oral Cavity Tumor><Malignant Oral Neoplasm><Malignant Oropharyngeal Neoplasm><Malignant Oropharyngeal Tumor><Malignant Tumor><Microscopic><Modality><Modeling><Molecular><Morbidity><Morbidity - disease rate><Mouth Cancer><Mouth Leukoplakia><NCI-Designated Cancer Center><Noncoding RNA><Nontranslated RNA><Oral><Oral Cancer><Oral Cavity Leukoplakia><Oral Cavity Squamous Cell Carcinoma><Oral Examination><Oral Keratosis><Oral Leukoplakia><Oral Stage><Oral squamous cell carcinoma><Oropharnyx Cancers><Oropharyngeal Cancer><Oropharyngeal Carcinoma><Oropharynx Cancer><Oropharynx Carcinoma><Patients><Persons><Play><Population Heterogeneity><Prevention><RNA Seq><RNA sequencing><RNAseq><Research Specimen><Risk><Risk Assessment><Role><Specimen><Survival Rate><T8 Cells><T8 Lymphocytes><Tissues><Tobacco><Transcript><Translations><Tumor-associated macrophages><Universities><Untranslated RNA><Validation><absence of HPV><absence of human papillomavirus><active followup><bio-markers><biobank><biologic marker><biomarker><biomarker identification><biorepository><causation><clinical biomarkers><clinical decision-making><clinically useful biomarkers><cohort><conventional therapy><conventional treatment><developmental><disease causation><diverse populations><early detection><follow up><follow-up><followed up><followup><heterogeneous population><high risk><hrHPV><human papillomavirus +><human papillomavirus associated oral cancer><human papillomavirus negative><human papillomavirus positive><identification of biomarkers><identification of new biomarkers><immune microenvironment><immune suppression><immune suppressive activity><immune suppressive function><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based biomarkers><immune-based therapies><immune-based treatments><immuno therapy><immunological biomarkers><immunological markers><immunosuppressive activity><immunosuppressive function><immunosuppressive microenvironment><immunosuppressive response><immunosuppressive tumor microenvironment><improved><machine based learning><malignancy><malignant mouth neoplasm><malignant mouth tumor><malignant oropharynx neoplasm><malignant oropharynx tumor><marker identification><mortality><mouth SCC><mouth lesion><mouth squamous cell carcinoma><multidisciplinary><neoplasm/cancer><neoplastic><noncoding><oral cancer associated with HPV><oral cancer caused by human papillomavirus><oral cavity SCC><oral cavity cancer><oral lesion><oral mucosa leukokeratosis><oral mucosa leukoplakia><oral oncogenic HPV><oral squamous cancer><oral squamous carcinoma><population diversity><precancer><precancerous><premalignant><presence of HPV><presence of human papillomavirus><progression biomarker><progression marker><racial diversity><racially diverse><recruit><response><risk prediction algorithm><risk prediction model><risk stratification><screening><screenings><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stratify risk><survival outcome><transcriptome sequencing><transcriptomic sequencing><transcriptomics><translation><tumor><tumor immune microenvironment><tumor-immune system interactions><validations><wart virus>
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Sylvia E Rosas

BOSTON MEDICAL CENTER, BOSTON, MA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$799,998
FY 2025

Project Title

Boston Chronic Kidney Disease Research Biopsy Center

Grant Number:

5U01DK133092-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Chronic kidney disease (CKD) affects 37 million Americans, costs tens of billions of dollars annually, and can lead to kidney failure, cardiovascular disease (CVD), and early mortality. CKD is not a single entity but rather a heterogeneous condition with a wide spectrum of underlying...

Research Terms

<21+ years old><Academic Medical Centers><Active Follow-up><Adult><Adult Human><Affect><Agreement><Amendment><American><Animal Model><Animal Models and Related Studies><Awareness><Biopsy><Biopsy Sample><Biopsy Specimen><Body Tissues><Boston><Brittle Diabetes Mellitus><Budgets><Cardiovascular Diseases><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinic><Clinical><Collection><Communities><Consent Documents><Consent Forms><Development><Diabetes Mellitus><Diabetic Kidney Disease><Diabetic Nephropathy><Disparity population><Dysfunction><ESKD><ESRD><Education><Educational aspects><Employment><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Endocrinologist><Endocrinology><Enrollment><Ensure><Ethics><Exclusion Criteria><Functional disorder><Geography><Glomerular Filtration Rate><Hospitals><Human><Hypertension><IDDM><Individual><Informed Consent Documents><Informed Consent Forms><Infrastructure><Insulin-Dependent Diabetes Mellitus><Interdisciplinary Research><Interdisciplinary Study><Investigation><Investigators><Israel><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Insufficiency><Kidney Urinary System><Knowledge><Laboratories><Leadership><Literature><Long-term cohort study><Longitudinal cohort study><Medical center><Metabolism and Endocrinology><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Nephrology><Nephropathy><P50 Mechanism><P50 Program><Participant><Pathologic><Pathology><Patients><Phase><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Physiopathology><Population><Population Heterogeneity><Primary Care Physician><Proteome><Protocol><Protocols documentation><Public Health><Radial><Radius><Renal Cell><Renal Disease><Renal Failure><Renal Insufficiency><Renal function><Research><Research Personnel><Researchers><Risk><Role><Safety><Science><Site><Socioeconomically disadvantaged><Spatial Distribution><Specialized Center><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Techniques><Tissue Sample><Tissue atlas><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><University Medical Centers><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vulnerable Populations><Woman><active followup><adjudication><adjudicative process and procedure><adulthood><cardiovascular disorder><chronic kidney disease><clinical research site><clinical site><community advisory board><community advisory committee><community advisory panel><cost><developmental><diabetes><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><diverse populations><eligible participant><enroll><ethical><ethnic minority><experience><follow up><follow-up><followed up><followup><global gene expression><global transcription profile><group disparity><group inequality><group inequity><heterogeneous population><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><inclusion criteria><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><insight><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kidney biopsy><kidney cell><kidney disorder><kidney function><literacy><member><metabolome><metabonome><model of animal><molecular pathology><mortality><new approaches><novel><novel approaches><novel strategies><novel strategy><participant engagement><participant enrollment><pathophysiology><patient engagement><patient enrollment><patient population><population diversity><population inequality><population inequity><precision medicine><precision-based medicine><primary care clinic><protocol development><racial minority><recruit><renal><renal biopsy><renal disorder><retention rate><retention strategy><safety net><social health determinants><social role><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><subgroup disparity><tertiary care><transcriptome><type I diabetes><type one diabetes><unequal group><unequal population><vulnerable group><vulnerable individual><vulnerable people>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sushrut S. Waikar

BOSTON MEDICAL CENTER, BOSTON, MA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$799,998
FY 2025

Project Title

Boston Chronic Kidney Disease Research Biopsy Center

Grant Number:

5U01DK133092-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Chronic kidney disease (CKD) affects 37 million Americans, costs tens of billions of dollars annually, and can lead to kidney failure, cardiovascular disease (CVD), and early mortality. CKD is not a single entity but rather a heterogeneous condition with a wide spectrum of underlying...

Research Terms

<21+ years old><Academic Medical Centers><Active Follow-up><Adult><Adult Human><Affect><Agreement><Amendment><American><Animal Model><Animal Models and Related Studies><Awareness><Biopsy><Biopsy Sample><Biopsy Specimen><Body Tissues><Boston><Brittle Diabetes Mellitus><Budgets><Cardiovascular Diseases><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinic><Clinical><Collection><Communities><Consent Documents><Consent Forms><Development><Diabetes Mellitus><Diabetic Kidney Disease><Diabetic Nephropathy><Disparity population><Dysfunction><ESKD><ESRD><Education><Educational aspects><Employment><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Endocrinologist><Endocrinology><Enrollment><Ensure><Ethics><Exclusion Criteria><Functional disorder><Geography><Glomerular Filtration Rate><Hospitals><Human><Hypertension><IDDM><Individual><Informed Consent Documents><Informed Consent Forms><Infrastructure><Insulin-Dependent Diabetes Mellitus><Interdisciplinary Research><Interdisciplinary Study><Investigation><Investigators><Israel><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Insufficiency><Kidney Urinary System><Knowledge><Laboratories><Leadership><Literature><Long-term cohort study><Longitudinal cohort study><Medical center><Metabolism and Endocrinology><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Nephrology><Nephropathy><P50 Mechanism><P50 Program><Participant><Pathologic><Pathology><Patients><Phase><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Physiopathology><Population><Population Heterogeneity><Primary Care Physician><Proteome><Protocol><Protocols documentation><Public Health><Radial><Radius><Renal Cell><Renal Disease><Renal Failure><Renal Insufficiency><Renal function><Research><Research Personnel><Researchers><Risk><Role><Safety><Science><Site><Socioeconomically disadvantaged><Spatial Distribution><Specialized Center><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Techniques><Tissue Sample><Tissue atlas><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><University Medical Centers><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vulnerable Populations><Woman><active followup><adjudication><adjudicative process and procedure><adulthood><cardiovascular disorder><chronic kidney disease><clinical research site><clinical site><community advisory board><community advisory committee><community advisory panel><cost><developmental><diabetes><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><diverse populations><eligible participant><enroll><ethical><ethnic minority><experience><follow up><follow-up><followed up><followup><global gene expression><global transcription profile><group disparity><group inequality><group inequity><heterogeneous population><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><inclusion criteria><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><insight><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kidney biopsy><kidney cell><kidney disorder><kidney function><literacy><member><metabolome><metabonome><model of animal><molecular pathology><mortality><new approaches><novel><novel approaches><novel strategies><novel strategy><participant engagement><participant enrollment><pathophysiology><patient engagement><patient enrollment><patient population><population diversity><population inequality><population inequity><precision medicine><precision-based medicine><primary care clinic><protocol development><racial minority><recruit><renal><renal biopsy><renal disorder><retention rate><retention strategy><safety net><social health determinants><social role><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><subgroup disparity><tertiary care><transcriptome><type I diabetes><type one diabetes><unequal group><unequal population><vulnerable group><vulnerable individual><vulnerable people>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LEIGH R HOCHBERG

BROWN UNIVERSITY, PROVIDENCE, RI

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$797,216
FY 2025

Project Title

Intuitive, complete neural control of tablet computers for communication

Grant Number:

5U01DC017844-06

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2019

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Conventional augmentative and alternative communication (AAC) devices for people with severe speech and motor impairments (SSMI) rely on residual motor function, inherently limiting communication throughput. Commercially available AAC solutions require daily caregiver setup, need fre...

Research Terms

<2-dimensional><AAC Device><AAC Intervention><Amyotrophic Lateral Sclerosis><Amyotrophic Lateral Sclerosis Motor Neuron Disease><Augmentative and Alternative Communication><BRAIN initiative><Brain><Brain Nervous System><Brain Research through Advancing Innovative Neurotechnologies initiative><Brain Stem Infarctions><Brainstem Infarctions><Brainstem Stroke><Calibration><Care Givers><Caregivers><Cell Communication and Signaling><Cell Signaling><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Communication><Competence><Computer software><Computers><Darkness><Data><Detection><Development><Devices><Dimensions><Disease><Disorder><Encephalon><Family><Fatigue><Feedback><Friends><Gehrig's Disease><Gestures><Hand><Home><Human><Human Activities><Illumination><Implant><Individual><Industry><Injury><Institution><Intention><Interactive Communication><Intracellular Communication and Signaling><Intuition><Knowledge><Lack of Energy><Language><Lighting><Location><Locked-In Syndrome><Lou Gehrig Disease><Methods><Mice><Mice Mammals><Modeling><Modern Man><Modernization><Motor><Motor Cortex><Movement><Murine><Mus><NIDCD><NIH><National Institute on Deafness and Other Communication Disorders><National Institutes of Health><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Outcome Measure><Palsy><Paralysed><Participant><Pattern><Performance><Persons><Plegia><Research><Research Support><Residual><Residual state><Signal Transduction><Signal Transduction Systems><Signaling><Software><Speech><Speed><Survey Instrument><Surveys><System><Tablet Computer><Tablets><Technology><Testing><Time><Touch><Touch sensation><Translating><Translations><United States National Institutes of Health><alternative communication><arm><awake><biological signal transduction><body movement><brain computer interface><brain implant><communication device><deep learning><deep learning method><deep learning strategy><design><designing><developmental><expectation><experience><feasibility trial><first in man><first-in-human><flexibility><flexible><hands><homes><iPad><improved><injuries><innovate><innovation><innovative><intuitive><long short term memory><measurable outcome><motor disease><motor disorder><motor dysfunction><motor impairment><movement impairment><movement limitation><neural><neural control><neural implant><neural regulation><neuromodulation><neuromodulatory><neuronal><neuroregulation><non-human primate><nonhuman primate><novel><outcome measurement><paralysis><paralytic><phrases><preference><tablet device><tactile sensation><tool><touch panel><touch screen><touch screen panel><touchscreen><touchscreen panel><translation><two-dimensional><wireless>
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Sean C Murphy

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$793,041
FY 2025

Project Title

Development of an oral liver-targeted prime-and-trap malaria vaccine

Grant Number:

5U01AI155313-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2020

End Date:

11/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Our U01 project supports NIAID’s mission to better understand, treat, and prevent infectious diseases by focusing on pre-erythrocytic malaria vaccine development. Vaccines that efficiently stop the Plasmodium sporozoite (spz) or liver stage can provide complete protection against malarial d...

Research Terms

<Acceleration><Adeno-Associated Viruses><Antigen Presentation><Antigens><Attenuated><Bile><Bile Acids><Bile Juice><Bile fluid><Biocompatible Materials><Biolistics><Biology><Biomaterials><Blood erythrocyte><Body Tissues><Brittle Diabetes Mellitus><CD8><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CD8B><CD8B1><CD8B1 gene><Cell Body><Cell-Mediated Lympholytic Cells><Cells><Cessation of life><Characteristics><Chemistry><Circulation><Clinical><Clinical Trials><Collaborations><Communicable Diseases><Communities><Coupled><Culicidae><Cytolytic T-Cell><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><DNA><DNA Therapy><DNA delivery><Data><Death><Deoxyribonucleic Acid><Dependoparvovirus><Dependovirus><Development><Diabetes Mellitus><Disease><Disorder><Doctor of Philosophy><Dose><Drug Delivery><Drug Delivery Systems><Engineering><Ensure><Entero-Hepatic Circulation><Enterohepatic Circulation><Erythrocytes><Erythrocytic><FDA approved><Formulation><Frequencies><Gene Combinations><Gene Transfer Clinical><Gene-Gun Technique><Genetic Intervention><Goals><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><Human><Humulin R><IDDM><Immune signaling><Immunity><Immunology><Infection><Infectious Diseases><Infectious Disorder><Injections><Insulin><Insulin-Dependent Diabetes Mellitus><Intravenous><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><LYT3><Laboratories><Life Cycle><Life Cycle Stages><Lipids><Literature><Liver><Liver Cells><Malaria><Malaria Diagnostic><Malaria Vaccines><Malarial Vaccines><Marrow erythrocyte><Memory><Methods><Mice><Mice Mammals><Mission><Modern Man><Mosquitoes><Murine><Mus><NIAID><National Institute of Allergy and Infectious Disease><Non-Polyadenylated RNA><Novolin R><Nucleic Acids><Oral><Oral Administration><Oral Drug Administration><Paludism><Parasites><Performance><Persons><Ph.D.><PhD><Pharmacology><Phase><Plasmodium><Plasmodium Infections><Plasmodium vaccine><Polymers><Preclinical Testing><RNA><RNA Gene Products><Radiation><Ramp><Red Blood Cells><Red Cell><Regimen><Regular Insulin><Reporting><Research Personnel><Researchers><Rhesus><Ribonucleic Acid><Safety><Salivary Glands><Scientist><Shapes><Small Intestines><Sporozoites><Sterility><Sudden-Onset Diabetes Mellitus><Surface><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><T8 Cells><T8 Lymphocytes><Testing><Therapeutic><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Universities><Vaccination><Vaccines><Viral><Washington><Work><absorption><adeno associated virus group><attenuate><attenuates><biological material><blood corpuscles><booster dose><booster shot><booster vaccine><cell killing><cell type><deliver DNA><deploy vaccines><develop a vaccine><develop vaccines><development of a vaccine><developmental><diabetes><distribute vaccines><first in man><first-in-human><gene gun><gene repair therapy><gene therapeutics><gene therapy><gene-based therapeutic><gene-based therapeutics><gene-based therapy><genes therapeutic><genes therapeutics><genetic therapy><genomic therapy><hepatic body system><hepatic organ system><immunogen><immunogenicity><improved><insulin dependent diabetes><insulin dependent type 1><intraoral drug delivery><intravenous administration><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><killer T cell><life course><manufacture><materials science><nano particle><nano-sized particle><nanoparticle><nanosized particle><next generation><non-human primate><nonhuman primate><novel><oral vaccine><plasmid DNA><polymer><polymeric><pre-clinical testing><prevent><preventing><rational design><recruit><resident memory T cell><small bowel><sterile><success><therapeutic gene><thymus derived lymphocyte><tissue resident memory T cell><tool><type I diabetes><type one diabetes><vaccine boost><vaccine deployment><vaccine development><vaccine distribution><vaccine roll-out><vaccine rollout><vaccine strategy><vaccines against malaria><vector>
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YOGISH C. KUDVA

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$790,565
FY 2025

Project Title

T1D-DN KPMP Urban Rural (T1D-DN KUR) Recruitment Site

Grant Number:

1U01DK144994-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2025

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT This application, submitted by a multi-disciplinary research team, responds to RFA-DK-25-022: Precision Medicine for Type 1 Diabetic Nephropathy (U01 Clinical Trial Not Allowed). The goal of the RFA is to expand the Kidney Precision Medicine Project (KPMP) by adding new rese...

Research Terms

<Active Follow-up><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Advocate><Ambulatory Blood Pressure Monitoring><Area><Biological Markers><Biopsy><Blood><Blood Reticuloendothelial System><Blood Serum><Blood capillaries><Body Tissues><Brittle Diabetes Mellitus><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cellular injury><Classification><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Code><Coding System><Cohort Studies><Collaborations><Collection><Commuting><Complications of Diabetes Mellitus><Concurrent Studies><Consent><Continuous Glucose Monitor><County><DWI (diffusion weighted imaging)><DWI-MRI><Data Bases><Data Collection><Databases><Development><Diabetes Complications><Diabetes-Related Complications><Diabetic Complications><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Disease Pathway><Disease Progression><Doppler OCT><Dyslipidemias><Effectiveness><Electronic Health Record><Electronics><Eligibility><Eligibility Determination><Endothelium><Enrollment><Epidemiology><Ethicists><Ethics Consultants><Event><Fibrosis><Frusemid><Furosemide><Fursemide><Future><Generations><Genetic><Genomics><Goals><Health Care Providers><Health Personnel><Health Status><Heart Vascular><Housing><IDDM><Individual><Injury><Injury to Kidney><Institution><Insulin-Dependent Diabetes Mellitus><Interdisciplinary Research><Interdisciplinary Study><Intervention Studies><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kidney><Kidney Urinary System><Knowledge><Laboratories><Level of Health><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical Records><Metabolic syndrome><Microcirculation><Minnesota><Morbidity><Morbidity - disease rate><Multidisciplinary Collaboration><Multidisciplinary Research><NMR Imaging><NMR Tomography><Nuclear Magnetic Resonance Imaging><OCT Tomography><Optical Coherence Tomography><Participant><Patient Outcomes Assessments><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient advocacy><Patients><Persons><Phenotype><Population><Position><Positioning Attribute><Proteomics><Protocol><Protocol Screening><Protocols documentation><Questionnaires><Registries><Renal function><Research><Research Resources><Resources><Retinal Diseases><Retinal Disorder><Risk Factors><Rural><Rural Population><Rural group><Rural people><Sampling><Serum><Site><Socio-economic status><Socioeconomic Status><Structure><Sudden-Onset Diabetes Mellitus><Surrogate End Points><Surrogate Endpoint><Surrogate Markers><System><Systematics><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Tissues><Troponin T><Tubular><Tubular formation><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Update><Urine><Visit><Wisconsin><Zeugmatography><active followup><acute kidney injury><bio-markers><biobank><biologic marker><biomarker><biorepository><capillary><cell damage><cell injury><cellular damage><circulatory system><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><dMRI><damage to cells><data base><developmental><diabetes control><diabetes distress><diabetes mellitus control><diabetic patient><diffusion tensor imaging><disease registry><drug discovery><electronic><electronic device><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><epidemiologic><epidemiological><experience><extracellular vesicles><follow up><follow-up><followed up><followup><gene testing><gene-based testing><genetic testing><health care personnel><health care worker><health level><health provider><health workforce><high risk><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><indexing><injuries><injury to cells><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><intervention research><interventional research><interventional study><interventions research><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kidney biopsy><kidney function><kidney injury><long-term study><longitudinal outcome studies><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><magnetic transfer imaging><magnetization transfer imaging><medical personnel><metabolism measurement><metabolomics><metabonomics><mortality><multiomics><multiple omics><novel><optical Doppler tomography><optical coherence Doppler tomography><panomics><participant recruitment><participant retention><phenotypic data><point of care><precision medicine><precision-based medicine><prevent><preventing><prospective><recruit><renal><renal biopsy><renal injury><retina disease><retina disorder><retinopathy><rural area><rural individual><rural location><rural region><sample archive><socio-economic><socio-economic position><socio-economically><socioeconomic position><socioeconomically><socioeconomics><surrogate bio-markers><surrogate biomarkers><tool><treatment provider><tropomyosin binding protein troponin T><type 1 diabetic><type I diabetes><type I diabetic><type one diabetes><urinary><validation studies><virtual health visit><virtual visit><waist circumference>
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Aleksandra Kukla

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$790,565
FY 2025

Project Title

T1D-DN KPMP Urban Rural (T1D-DN KUR) Recruitment Site

Grant Number:

1U01DK144994-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2025

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT This application, submitted by a multi-disciplinary research team, responds to RFA-DK-25-022: Precision Medicine for Type 1 Diabetic Nephropathy (U01 Clinical Trial Not Allowed). The goal of the RFA is to expand the Kidney Precision Medicine Project (KPMP) by adding new rese...

Research Terms

<Active Follow-up><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Advocate><Ambulatory Blood Pressure Monitoring><Area><Biological Markers><Biopsy><Blood><Blood Reticuloendothelial System><Blood Serum><Blood capillaries><Body Tissues><Brittle Diabetes Mellitus><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cellular injury><Classification><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Code><Coding System><Cohort Studies><Collaborations><Collection><Commuting><Complications of Diabetes Mellitus><Concurrent Studies><Consent><Continuous Glucose Monitor><County><DWI (diffusion weighted imaging)><DWI-MRI><Data Bases><Data Collection><Databases><Development><Diabetes Complications><Diabetes-Related Complications><Diabetic Complications><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Disease Pathway><Disease Progression><Doppler OCT><Dyslipidemias><Effectiveness><Electronic Health Record><Electronics><Eligibility><Eligibility Determination><Endothelium><Enrollment><Epidemiology><Ethicists><Ethics Consultants><Event><Fibrosis><Frusemid><Furosemide><Fursemide><Future><Generations><Genetic><Genomics><Goals><Health Care Providers><Health Personnel><Health Status><Heart Vascular><Housing><IDDM><Individual><Injury><Injury to Kidney><Institution><Insulin-Dependent Diabetes Mellitus><Interdisciplinary Research><Interdisciplinary Study><Intervention Studies><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kidney><Kidney Urinary System><Knowledge><Laboratories><Level of Health><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical Records><Metabolic syndrome><Microcirculation><Minnesota><Morbidity><Morbidity - disease rate><Multidisciplinary Collaboration><Multidisciplinary Research><NMR Imaging><NMR Tomography><Nuclear Magnetic Resonance Imaging><OCT Tomography><Optical Coherence Tomography><Participant><Patient Outcomes Assessments><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient advocacy><Patients><Persons><Phenotype><Population><Position><Positioning Attribute><Proteomics><Protocol><Protocol Screening><Protocols documentation><Questionnaires><Registries><Renal function><Research><Research Resources><Resources><Retinal Diseases><Retinal Disorder><Risk Factors><Rural><Rural Population><Rural group><Rural people><Sampling><Serum><Site><Socio-economic status><Socioeconomic Status><Structure><Sudden-Onset Diabetes Mellitus><Surrogate End Points><Surrogate Endpoint><Surrogate Markers><System><Systematics><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Tissues><Troponin T><Tubular><Tubular formation><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Update><Urine><Visit><Wisconsin><Zeugmatography><active followup><acute kidney injury><bio-markers><biobank><biologic marker><biomarker><biorepository><capillary><cell damage><cell injury><cellular damage><circulatory system><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><dMRI><damage to cells><data base><developmental><diabetes control><diabetes distress><diabetes mellitus control><diabetic patient><diffusion tensor imaging><disease registry><drug discovery><electronic><electronic device><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><epidemiologic><epidemiological><experience><extracellular vesicles><follow up><follow-up><followed up><followup><gene testing><gene-based testing><genetic testing><health care personnel><health care worker><health level><health provider><health workforce><high risk><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><indexing><injuries><injury to cells><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><intervention research><interventional research><interventional study><interventions research><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kidney biopsy><kidney function><kidney injury><long-term study><longitudinal outcome studies><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><magnetic transfer imaging><magnetization transfer imaging><medical personnel><metabolism measurement><metabolomics><metabonomics><mortality><multiomics><multiple omics><novel><optical Doppler tomography><optical coherence Doppler tomography><panomics><participant recruitment><participant retention><phenotypic data><point of care><precision medicine><precision-based medicine><prevent><preventing><prospective><recruit><renal><renal biopsy><renal injury><retina disease><retina disorder><retinopathy><rural area><rural individual><rural location><rural region><sample archive><socio-economic><socio-economic position><socio-economically><socioeconomic position><socioeconomically><socioeconomics><surrogate bio-markers><surrogate biomarkers><tool><treatment provider><tropomyosin binding protein troponin T><type 1 diabetic><type I diabetes><type I diabetic><type one diabetes><urinary><validation studies><virtual health visit><virtual visit><waist circumference>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joycelyn Lawrence

UNIVERSITY OF MIAMI CORAL GABLES, CORAL GABLES, FL

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$782,953
FY 2025

Project Title

Implementation of Comprehensive Survivorship Care Intervention Across FQHC-Based Primary Care Practices

Grant Number:

5U01CA290611-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/5/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Cancer survivorship challenges adversely contribute to cancer burden, morbidity and mortality, and are exacerbated by multiple health care and contextual barriers such as oncology provider shortages, and limited comprehensive survivorship care services in primary care (PC). There is a critical need ...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Access to Care><Active Follow-up><Acute><Address><Adherence><Adult><Adult Human><Aged 65 and Over><Anxiety><Area><Assess implementation><Attention><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Cancer Burden><Cancer Center><Cancer Survivor><Cancer Survivorship><Cancers><Caring><Catchment Area><Chronic><Clinic><Cluster randomization trial><Cluster randomized trial><Collaborations><Communication><Communities><Community Health><Community Health Systems><Complex><Computerized Medical Record><Conditioning Therapy><Critical Care><Distress><Early Diagnosis><Early treatment><Education><Educational aspects><Electronic Medical Record><Environment><Evaluation><Evidence based intervention><Evidence based program><Face><Fatigue><Federally Qualified Health Center><Florida><Future><Guidelines><Health><Health Care><Health Care Utilization><Health Services Accessibility><Health Services Evaluation><Health Services Research><Health system><Implementation assessment><Informatics><Infrastructure><Internet><Intervention><Joints><Lack of Energy><Life Style><Lifestyle><Link><Long-Term Survivorship><Malignant Neoplasms><Malignant Tumor><Medical Care Research><Medical Informatics><Medical Oncology><Mental Depression><Morbidity><Morbidity - disease rate><National Cancer Burden><Nutrition><Oncologist><Oncology><Oncology Cancer><Outcome><Pain><Painful><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Physical activity><Population><Practice Guidelines><Prevention><Primary Care><Printing><Process><Provider><QOC><Quality of Care><RE-AIM><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Recurrence><Recurrent><Research><Research Design><Research Resources><Resources><Science><Second Cancer><Second Primary Cancers><Secondary Malignancy><Secondary Malignant Neoplasm><Self Management><Spirituality><Study Type><Survivors><Symptom Burden><System><Training><Training Programs><Treatment Efficacy><WWW><Work><above age 65><access to health services><access to services><access to treatment><accessibility to health services><active followup><adulthood><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><assess effectiveness><availability of services><behavior intervention><behavioral intervention><cancer care><cancer education><cancer survivor care><cancer survivorship care><cancer type><care access><care coordination><care resources><care services><care systems><co-morbid><co-morbidity><community based design><community based research><community clinic><community-based health><comorbidity><coordinating care><depression><determine effectiveness><dissemination science><early detection><early therapy><effectiveness assessment><effectiveness evaluation><effectiveness/implementation design><effectiveness/implementation hybrid design><effectiveness/implementation hybrid study><effectiveness/implementation study><evaluate effectiveness><evaluate implementation><evaluation of implementation><evidence base><examine effectiveness><faces><facial><follow up><follow-up><followed up><followup><health care resources><health care service use><health care service utilization><health related quality of life><health service access><health services availability><human old age (65+)><implementation evaluation><implementation science><implementation/effectiveness><improved><intervention efficacy><m-Health><mHealth><malignancy><mobile health><mortality><neoplasm/cancer><old age><oncology service><over 65 years><patient portal><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><primary care clinic><primary care clinician><primary care health service><primary care practice><primary care setting><primary health service><primary outcome><programs><psychologic><psychological><psychosocial><randomized, clinical trials><reach, efficacy, adoption, implementation, and maintenance><recruit><risk stratification><satisfaction><screening><screenings><secondary cancer><secondary outcome><sedentary activity><service availability><services research><side effect><social><standard of care><stratify risk><study design><survivorship><technology implementation><technology validation><therapeutic efficacy><therapy efficacy><tool><treatment access><trial design><web><world wide web><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Frank J Penedo

UNIVERSITY OF MIAMI CORAL GABLES, CORAL GABLES, FL

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$782,953
FY 2025

Project Title

Implementation of Comprehensive Survivorship Care Intervention Across FQHC-Based Primary Care Practices

Grant Number:

5U01CA290611-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/5/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Cancer survivorship challenges adversely contribute to cancer burden, morbidity and mortality, and are exacerbated by multiple health care and contextual barriers such as oncology provider shortages, and limited comprehensive survivorship care services in primary care (PC). There is a critical need ...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Access to Care><Active Follow-up><Acute><Address><Adherence><Adult><Adult Human><Aged 65 and Over><Anxiety><Area><Assess implementation><Attention><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Cancer Burden><Cancer Center><Cancer Survivor><Cancer Survivorship><Cancers><Caring><Catchment Area><Chronic><Clinic><Cluster randomization trial><Cluster randomized trial><Collaborations><Communication><Communities><Community Health><Community Health Systems><Complex><Computerized Medical Record><Conditioning Therapy><Critical Care><Distress><Early Diagnosis><Early treatment><Education><Educational aspects><Electronic Medical Record><Environment><Evaluation><Evidence based intervention><Evidence based program><Face><Fatigue><Federally Qualified Health Center><Florida><Future><Guidelines><Health><Health Care><Health Care Utilization><Health Services Accessibility><Health Services Evaluation><Health Services Research><Health system><Implementation assessment><Informatics><Infrastructure><Internet><Intervention><Joints><Lack of Energy><Life Style><Lifestyle><Link><Long-Term Survivorship><Malignant Neoplasms><Malignant Tumor><Medical Care Research><Medical Informatics><Medical Oncology><Mental Depression><Morbidity><Morbidity - disease rate><National Cancer Burden><Nutrition><Oncologist><Oncology><Oncology Cancer><Outcome><Pain><Painful><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Physical activity><Population><Practice Guidelines><Prevention><Primary Care><Printing><Process><Provider><QOC><Quality of Care><RE-AIM><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Recurrence><Recurrent><Research><Research Design><Research Resources><Resources><Science><Second Cancer><Second Primary Cancers><Secondary Malignancy><Secondary Malignant Neoplasm><Self Management><Spirituality><Study Type><Survivors><Symptom Burden><System><Training><Training Programs><Treatment Efficacy><WWW><Work><above age 65><access to health services><access to services><access to treatment><accessibility to health services><active followup><adulthood><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><assess effectiveness><availability of services><behavior intervention><behavioral intervention><cancer care><cancer education><cancer survivor care><cancer survivorship care><cancer type><care access><care coordination><care resources><care services><care systems><co-morbid><co-morbidity><community based design><community based research><community clinic><community-based health><comorbidity><coordinating care><depression><determine effectiveness><dissemination science><early detection><early therapy><effectiveness assessment><effectiveness evaluation><effectiveness/implementation design><effectiveness/implementation hybrid design><effectiveness/implementation hybrid study><effectiveness/implementation study><evaluate effectiveness><evaluate implementation><evaluation of implementation><evidence base><examine effectiveness><faces><facial><follow up><follow-up><followed up><followup><health care resources><health care service use><health care service utilization><health related quality of life><health service access><health services availability><human old age (65+)><implementation evaluation><implementation science><implementation/effectiveness><improved><intervention efficacy><m-Health><mHealth><malignancy><mobile health><mortality><neoplasm/cancer><old age><oncology service><over 65 years><patient portal><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><primary care clinic><primary care clinician><primary care health service><primary care practice><primary care setting><primary health service><primary outcome><programs><psychologic><psychological><psychosocial><randomized, clinical trials><reach, efficacy, adoption, implementation, and maintenance><recruit><risk stratification><satisfaction><screening><screenings><secondary cancer><secondary outcome><sedentary activity><service availability><services research><side effect><social><standard of care><stratify risk><study design><survivorship><technology implementation><technology validation><therapeutic efficacy><therapy efficacy><tool><treatment access><trial design><web><world wide web><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Heather Chandler

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$745,148
FY 2025

Project Title

First Aid Medicine to Treat Vesicant Induced Corneal Injury

Grant Number:

5U01EY032973-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Sulfur mustard (SM) and nitrogen mustard (NM) are potent chemical threats that cause damage to the cornea, including acute photophobia and corneal lesions followed by loss of limbal stem cells (LSCs) and prolonged ulceration and vascularization. Therapeutic approaches targeting both ...

Research Terms

<Ablation><Acute><Advanced Development><Affect><Animal Model><Animal Models and Related Studies><Aqueous Humor><Autoregulation><Benefits and Risks><Biology><Bis(beta-chloroethyl) Sulfide><Cell Components><Cell Structure><Cell membrane><Cellular Structures><Chemicals><Chloramin><Chlorethazine><Chlormethine><Contracting Opportunities><Contracts><Cornea><Corneal Injury><Cutaneous><Cytoplasmic Membrane><Data><Dermal><Development><Di-2-chloroethyl Sulfide><Dichlorodiethyl Sulfide><Domestic Rabbit><Dose><Environment><Epithelial Cells><Event><Eye><Eye Drops><Eye Injuries><Eyeball><Eyedrops><Fibrosis><Film><First Aid><Goals><Goblet Cells><HN-2><HN2><Homeostasis><Human><IND Filing><IND application><IND package><IND submission><Immune response><In Vitro><Infiltration><Injury><Intraocular Fluid><Investigational New Drug Application><Joints><Knowledge><Lesion><Light Sensitivity><Lung symptom><Manuscripts><Measures><Mechlorethamine><Medical><Medicine><Methylchlorethamine><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Mustard Gas><Mustine><NIH><National Institutes of Health><Nature><Nitrogen Mustard><Ocular Injury><Ocular Pathology><Ohio><Organ><Oryctolagus cuniculus><Patients><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phase><Photophobia><Physiological Homeostasis><Physiology><Plasma Membrane><Process><Production><Progenitor Cells><Program Development><Protein Family><Proteins><Protocol><Protocols documentation><Publishing><Pulmonary Body System><Pulmonary Organ System><Rabbits><Rabbits Mammals><Reagent><Recombinants><Regenerative Medicine><Regenerative capacity><Regimen><Regulatory approval><Resistance><Respiratory System><Respiratory Tracts><Respiratory tract structure><Rodent><Rodentia><Rodents Mammals><Role><Safety><Societies><Stress><Sulfur Mustard><Surface><Symptoms><T-Cell Antigen Receptor-Interacting Molecule><T-Cell Receptor-Associated Transmembrane Adaptor 1><TRAT1><TRC-Interacting Molecule><TRIM><TRIM Gene><Technology><Therapeutic><Topical Drug Administration><Topical application><Toxic effect><Toxicities><Toxicology><Transgenic Mice><Treatment Efficacy><Ulcer><Ulceration><United States National Institutes of Health><Universities><Vascularization><Vesicants><Wild Type Mouse><Wound Repair><Yellow Cross Liquid><Yperite><apply topically><chemical threat><chloromethine><corneal><corneal epithelial><corneal epithelial progenitor><corneal epithelial stem cells><corneal epithelial wound healing><corneal epithelium><corneal wound><corneal wound healing><deliver topically><developmental><epithelium regeneration><extracellular><eye trauma><host response><immune system response><immunoresponse><improved><in vivo><injuries><injury response><injury to tissue><intervention efficacy><irritation><limbal><live cell image><live cell imaging><live cellular image><live cellular imaging><member><model of animal><native protein drug><novel><ocular surface><ocular trauma><pharmaceutical><pharmaceutical protein><plasmalemma><preservation><progenitor cell function><progenitor cell survival><progenitor function><progenitor survival><programs><protein drug agent><protein-based drug><pulmonary symptom><re-epithelialization><regenerate epithelium><regeneration ability><regeneration capacity><regulatory authorization><regulatory certification><regulatory clearance><repair><repaired><resistant><response to injury><screening program><social role><stem and progenitor cell function><stem and progenitor function><stem cell function><stem cell survival><stem cells><therapeutic efficacy><therapeutic protein><therapy efficacy><tissue injury><tissue repair><topical administration><topical delivery><topical drug application><topical drug delivery><topical instillation><topical treatment><treat topically><validation studies><wildtype mouse><wound healing><wound recovery><wound resolution>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jianjie Ma

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$745,148
FY 2025

Project Title

First Aid Medicine to Treat Vesicant Induced Corneal Injury

Grant Number:

5U01EY032973-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Sulfur mustard (SM) and nitrogen mustard (NM) are potent chemical threats that cause damage to the cornea, including acute photophobia and corneal lesions followed by loss of limbal stem cells (LSCs) and prolonged ulceration and vascularization. Therapeutic approaches targeting both ...

Research Terms

<Ablation><Acute><Advanced Development><Affect><Animal Model><Animal Models and Related Studies><Aqueous Humor><Autoregulation><Benefits and Risks><Biology><Bis(beta-chloroethyl) Sulfide><Cell Components><Cell Structure><Cell membrane><Cellular Structures><Chemicals><Chloramin><Chlorethazine><Chlormethine><Contracting Opportunities><Contracts><Cornea><Corneal Injury><Cutaneous><Cytoplasmic Membrane><Data><Dermal><Development><Di-2-chloroethyl Sulfide><Dichlorodiethyl Sulfide><Domestic Rabbit><Dose><Environment><Epithelial Cells><Event><Eye><Eye Drops><Eye Injuries><Eyeball><Eyedrops><Fibrosis><Film><First Aid><Goals><Goblet Cells><HN-2><HN2><Homeostasis><Human><IND Filing><IND application><IND package><IND submission><Immune response><In Vitro><Infiltration><Injury><Intraocular Fluid><Investigational New Drug Application><Joints><Knowledge><Lesion><Light Sensitivity><Lung symptom><Manuscripts><Measures><Mechlorethamine><Medical><Medicine><Methylchlorethamine><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Mustard Gas><Mustine><NIH><National Institutes of Health><Nature><Nitrogen Mustard><Ocular Injury><Ocular Pathology><Ohio><Organ><Oryctolagus cuniculus><Patients><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phase><Photophobia><Physiological Homeostasis><Physiology><Plasma Membrane><Process><Production><Progenitor Cells><Program Development><Protein Family><Proteins><Protocol><Protocols documentation><Publishing><Pulmonary Body System><Pulmonary Organ System><Rabbits><Rabbits Mammals><Reagent><Recombinants><Regenerative Medicine><Regenerative capacity><Regimen><Regulatory approval><Resistance><Respiratory System><Respiratory Tracts><Respiratory tract structure><Rodent><Rodentia><Rodents Mammals><Role><Safety><Societies><Stress><Sulfur Mustard><Surface><Symptoms><T-Cell Antigen Receptor-Interacting Molecule><T-Cell Receptor-Associated Transmembrane Adaptor 1><TRAT1><TRC-Interacting Molecule><TRIM><TRIM Gene><Technology><Therapeutic><Topical Drug Administration><Topical application><Toxic effect><Toxicities><Toxicology><Transgenic Mice><Treatment Efficacy><Ulcer><Ulceration><United States National Institutes of Health><Universities><Vascularization><Vesicants><Wild Type Mouse><Wound Repair><Yellow Cross Liquid><Yperite><apply topically><chemical threat><chloromethine><corneal><corneal epithelial><corneal epithelial progenitor><corneal epithelial stem cells><corneal epithelial wound healing><corneal epithelium><corneal wound><corneal wound healing><deliver topically><developmental><epithelium regeneration><extracellular><eye trauma><host response><immune system response><immunoresponse><improved><in vivo><injuries><injury response><injury to tissue><intervention efficacy><irritation><limbal><live cell image><live cell imaging><live cellular image><live cellular imaging><member><model of animal><native protein drug><novel><ocular surface><ocular trauma><pharmaceutical><pharmaceutical protein><plasmalemma><preservation><progenitor cell function><progenitor cell survival><progenitor function><progenitor survival><programs><protein drug agent><protein-based drug><pulmonary symptom><re-epithelialization><regenerate epithelium><regeneration ability><regeneration capacity><regulatory authorization><regulatory certification><regulatory clearance><repair><repaired><resistant><response to injury><screening program><social role><stem and progenitor cell function><stem and progenitor function><stem cell function><stem cell survival><stem cells><therapeutic efficacy><therapeutic protein><therapy efficacy><tissue injury><tissue repair><topical administration><topical delivery><topical drug application><topical drug delivery><topical instillation><topical treatment><treat topically><validation studies><wildtype mouse><wound healing><wound recovery><wound resolution>
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Hua Zhu

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$745,148
FY 2025

Project Title

First Aid Medicine to Treat Vesicant Induced Corneal Injury

Grant Number:

5U01EY032973-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Sulfur mustard (SM) and nitrogen mustard (NM) are potent chemical threats that cause damage to the cornea, including acute photophobia and corneal lesions followed by loss of limbal stem cells (LSCs) and prolonged ulceration and vascularization. Therapeutic approaches targeting both ...

Research Terms

<Ablation><Acute><Advanced Development><Affect><Animal Model><Animal Models and Related Studies><Aqueous Humor><Autoregulation><Benefits and Risks><Biology><Bis(beta-chloroethyl) Sulfide><Cell Components><Cell Structure><Cell membrane><Cellular Structures><Chemicals><Chloramin><Chlorethazine><Chlormethine><Contracting Opportunities><Contracts><Cornea><Corneal Injury><Cutaneous><Cytoplasmic Membrane><Data><Dermal><Development><Di-2-chloroethyl Sulfide><Dichlorodiethyl Sulfide><Domestic Rabbit><Dose><Environment><Epithelial Cells><Event><Eye><Eye Drops><Eye Injuries><Eyeball><Eyedrops><Fibrosis><Film><First Aid><Goals><Goblet Cells><HN-2><HN2><Homeostasis><Human><IND Filing><IND application><IND package><IND submission><Immune response><In Vitro><Infiltration><Injury><Intraocular Fluid><Investigational New Drug Application><Joints><Knowledge><Lesion><Light Sensitivity><Lung symptom><Manuscripts><Measures><Mechlorethamine><Medical><Medicine><Methylchlorethamine><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Mustard Gas><Mustine><NIH><National Institutes of Health><Nature><Nitrogen Mustard><Ocular Injury><Ocular Pathology><Ohio><Organ><Oryctolagus cuniculus><Patients><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phase><Photophobia><Physiological Homeostasis><Physiology><Plasma Membrane><Process><Production><Progenitor Cells><Program Development><Protein Family><Proteins><Protocol><Protocols documentation><Publishing><Pulmonary Body System><Pulmonary Organ System><Rabbits><Rabbits Mammals><Reagent><Recombinants><Regenerative Medicine><Regenerative capacity><Regimen><Regulatory approval><Resistance><Respiratory System><Respiratory Tracts><Respiratory tract structure><Rodent><Rodentia><Rodents Mammals><Role><Safety><Societies><Stress><Sulfur Mustard><Surface><Symptoms><T-Cell Antigen Receptor-Interacting Molecule><T-Cell Receptor-Associated Transmembrane Adaptor 1><TRAT1><TRC-Interacting Molecule><TRIM><TRIM Gene><Technology><Therapeutic><Topical Drug Administration><Topical application><Toxic effect><Toxicities><Toxicology><Transgenic Mice><Treatment Efficacy><Ulcer><Ulceration><United States National Institutes of Health><Universities><Vascularization><Vesicants><Wild Type Mouse><Wound Repair><Yellow Cross Liquid><Yperite><apply topically><chemical threat><chloromethine><corneal><corneal epithelial><corneal epithelial progenitor><corneal epithelial stem cells><corneal epithelial wound healing><corneal epithelium><corneal wound><corneal wound healing><deliver topically><developmental><epithelium regeneration><extracellular><eye trauma><host response><immune system response><immunoresponse><improved><in vivo><injuries><injury response><injury to tissue><intervention efficacy><irritation><limbal><live cell image><live cell imaging><live cellular image><live cellular imaging><member><model of animal><native protein drug><novel><ocular surface><ocular trauma><pharmaceutical><pharmaceutical protein><plasmalemma><preservation><progenitor cell function><progenitor cell survival><progenitor function><progenitor survival><programs><protein drug agent><protein-based drug><pulmonary symptom><re-epithelialization><regenerate epithelium><regeneration ability><regeneration capacity><regulatory authorization><regulatory certification><regulatory clearance><repair><repaired><resistant><response to injury><screening program><social role><stem and progenitor cell function><stem and progenitor function><stem cell function><stem cell survival><stem cells><therapeutic efficacy><therapeutic protein><therapy efficacy><tissue injury><tissue repair><topical administration><topical delivery><topical drug application><topical drug delivery><topical instillation><topical treatment><treat topically><validation studies><wildtype mouse><wound healing><wound recovery><wound resolution>
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Manuela Corti

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$730,189
FY 2025

Project Title

Immunomodulation Approaches to Improve Safety And Efficacy of Gene Therapy Treatment in Friedreich’s Ataxia

Grant Number:

5U01NS116752-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary / Abstract Friedreich’s ataxia (FA) is the most common form of hereditary ataxia, affecting ~1 in every 50,000 people in the US. FA is an autosomal recessive condition caused by the inheritance of a GAA trinucleotide repeat expansions in the frataxin (FXN) gene, which results in red...

Research Terms

<0-11 years old><AAV delivered><AAV delivery><AAV vector><AAV-based delivery><AAV-based vector><AAV-based viral delivery><AAV-mediated delivery><Ab response><Abscission><Acceleration><Address><Adeno-Associated Viruses><Adeno-associated-virus-based delivery><Adverse Experience><Adverse event><Affect><Age><Animals><Antibodies><Antibody Formation><Antibody Production><Antibody titer measurement><Antibody-Secreting Cells><B blood cells><B cell><B cells><B-Cell Activation><B-Cells><B-Lymphocytes><B-cell><BBB crossing><Benlysta><Biodistribution><Blood Plasma Cell><Bortezomib><C2B8 Monoclonal Antibody><Capsid><Capsid Proteins><Cardiac><Cessation of life><Child><Child Youth><Children (0-21)><Clinical><Clinical Data><Clinical Research><Clinical Study><Clinical Treatment Moab><Coat Proteins><Comment><Commentary><DNA Therapy><Data><Death><Dependoparvovirus><Dependovirus><Disease><Disorder><Dose><Editorial Comment><Enrollment><Environmental Exposure><Excision><Exclusion><Exposure to><Extirpation><Face><Familial Spinocerebellar Degenerations><Freidreich's Ataxia><Friedreich Ataxia><Friedreich Disease><Friedreich Spinocerebellar Ataxia><Friedreich's Familial Ataxia><Friedreich's Hereditary Ataxia><Friedreich's Hereditary Spinal Ataxia><Friedreich's tabes><Gene Expression><Gene Transfer Clinical><Gene therapy trial><Genes><Genetic><Genetic Diseases><Genetic Intervention><Goals><Heart><Hematology><Hereditary><Hereditary Ataxia><Hereditary Spinal Sclerosis><Hereditary Spinocerebellar Degenerations><Histopathology><Human><IGIV><IV Immunoglobulins><IVIG><Immune globulin IV><Immune response><Immunity><Immunoglobulin-Secreting Cells><Immunomodulation><Individual><Infusion><Infusion procedures><Inherited><Inherited Spinocerebellar Degenerations><Intravenous Antibodies><Intravenous IG><Intravenous Immune Globulin><Intravenous Immunoglobulins><JC Polyomavirus Encephalitis><JC Polyomavirus Encephalopathy><Length of Life><Longevity><MabThera><Mediating><Mice><Mice Mammals><Mitochondria><Modern Man><Monoclonal Antibodies><Murine><Mus><Nervous System><Nervous System Diseases><Nervous System Disorder><Neurologic Body System><Neurologic Disorders><Neurologic Organ System><Neurological Disorders><Neuromuscular Diseases><Patients><Persons><Plasma Cells><Plasmacytes><Preclinical data><Product Approvals><Progressive Multifocal Leukoencephalopathy><Proteasome Inhibitor><Published Comment><QOL><Quality of life><Rapamune><Rapamycin><Reaction><Recombinants><Regimen><Removal><Rituxan><Route><Safety><Sirolimus><Surgical Removal><System><T-Cell Activation><T-Cells><T-Lymphocyte><Testing><Therapeutic><Therapeutic Effect><Time><Toxic effect><Toxicities><Toxicology><Transgenes><Treatment Efficacy><Trinucleotide Repeat Expansion><Ventricular Arrhythmia><Viewpoint><Viral><Viral Coat Proteins><Viral Outer Coat Protein><Wild Type Mouse><Work><activate T cells><activated B cells><adaptive immune response><adeno associated virus group><adeno-associated viral vector><adeno-associated viral vector delivery><adeno-associated virus delivery><adeno-associated virus mediated delivery><adeno-associated virus vector><adenovirus mediated delivery><adult youth><ages><antibody biosynthesis><antibody titering><autosome><belimumab><blood-brain barrier crossing><bloodbrain barrier crossing><delivered with AAV><delivery with AAV><effective therapy><effective treatment><enroll><experiment><experimental research><experimental study><experiments><faces><facial><family ataxia><first in man><first-in-human><frataxin><gene repair therapy><gene replacement><gene replacement therapy><gene therapy><gene transfer trial><gene-based therapy><genetic condition><genetic disorder><genetic therapy><genomic therapy><host response><immune modulating strategy><immune modulation><immune modulatory strategy><immune regulation><immune system response><immunogenicity><immunoglobulin biosynthesis><immunologic reactivity control><immunomodulatory><immunomodulatory strategy><immunoregulation><immunoregulatory><immunoresponse><improved><infusions><intervention efficacy><kids><life span><lifespan><mAbs><mTOR Inhibitor><mitochondrial><monoclonal Abs><myoneural disorder><neurological disease><neuromuscular><neuromuscular degenerative disorder><neuromuscular disorder><non-human primate><nonhuman primate><participant enrollment><patient enrollment><plasmocyte><pre-clinical study><preclinical findings><preclinical information><preclinical study><premature><prematurity><prevent><preventing><programs><resection><response><rituximab><success><therapeutic efficacy><therapeutically effective><therapy efficacy><thymus derived lymphocyte><transgene><transgene expression><vector><wildtype mouse><young adult><young adult age><young adulthood><youngster>
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Shama Ahmad

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$704,952
FY 2025

Project Title

Novel lead compound advancement for mitigating halogen-induced mortality and morbidity.

Grant Number:

5U01ES033263-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/16/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Summary: Chlorine and bromine (Cl2 and Br2) are highly reactive and extremely toxic halogen gases that cause debilitating cardiopulmonary injury and death. Research from our previously funded ‘Identification of Therapeutic Lead Compounds U01’ provided published and preliminary data that identified c...

Research Terms

<1st World War><ATP phosphohydrolase (Ca(2+)-transporting)><Acute><Adsorption><Animal Model><Animal Models and Related Studies><Animals><Antidotes><Assay><Authoritarianism><Bioassay><Bioavailability><Biological><Biological Assay><Biological Availability><Biological Markers><Blood Cells><Blood Plasma><Blood Pressure><Body Tissues><Brain><Brain Nervous System><Bromine><CANP-I><Ca(2+)-Transporting ATPase><Ca2+ ATPase><Ca2+ transporting ATPase><Ca2+-Activated Protease><Calcium><Calcium ATPase><Calcium Adenosine Triphosphatase><Calcium Pump><Calcium-Activated Neutral Protease><Calcium-Activated Neutral Proteinase><Calcium-Activated Protease><Calcium-Dependent Neutral Protease><Calcium-Dependent Neutral Proteinase><Calpain><Cardiac><Cardiac Chronotropism><Cardiac Output><Cardiopulmonary><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cells><Cellular Matrix><Cessation of life><Chemicals><Chlorine><Cl element><Clinical><Clinical Chemistry><Common Rat Strains><Complete Blood Count><Cytoskeletal System><Cytoskeleton><Data><Death><Desminase><Development><Domestic Rabbit><Dose><Drug Design><Drug Kinetics><Drugs><Encephalon><Endoplasmic Reticulum><Epithelium><Ergastoplasm><Esteroproteases><Evaluation><Excretory function><Exposure to><First World War><Formulation><Funding><Gases><Goals><Great War><Group 17 Elements><Half-Life><Halogens><Heart><Heart Hypertrophy><Heart Injuries><Heart Rate><Heart Vascular><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><In Vitro><Individual><Industrialization><Inhalation><Inhaling><Injury><Intermediary Metabolism><Intramuscular><Intraventricular Pressure><Kidney><Kidney Urinary System><Lead><Liver><Liver Cells><Lung><Lung Respiratory System><Lung damage><Maximal Tolerated Dose><Maximally Tolerated Dose><Maximum Tolerated Dose><Mediating><Medication><Medicinal Chemistry><Metabolic Processes><Metabolism><Modeling><Molecular Target><Morbidity><Morbidity - disease rate><Muscle Cells><Myocardial><Myocardium><Myocytes><NIH><National Institutes of Health><O element><O2 element><Oral><Oryctolagus cuniculus><Oxygen><Papain-Like Cysteine Protease><Paramedic><Paramedical Personnel><Parents><Pb element><Peptidases><Peptide Hydrolases><Peripheral Blood Cell><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Pharmaceutical Preparations><Pharmacokinetics><Physiologic Availability><Physiologic intraventricular pressure><Plasma><Plasma Serum><Property><Protease Gene><Proteases><Protein Cleavage><Proteinases><Proteolysis><Proteolytic Enzymes><Publishing><Pulmonary Edema><Rabbits><Rabbits Mammals><Rat><Rats Mammals><Rattus><Renal Cell><Research><Reticuloendothelial System, Serum, Plasma><Route><Safety><Site><Soldier><Solubility><Spleen><Spleen Reticuloendothelial System><Structure><Structure-Activity Relationship><Survivors><Testing><Therapeutic><Therapeutic Agents><Theriacs><Tissues><Toxic effect><Toxicities><United States National Institutes of Health><Validation><Vendor><Ventricular Pressure><World War I><analog><animal rule><authoritarian><bio-markers><biologic><biologic marker><biomarker><calcium transporting ATPase><calcium-activated neutral protease inhibitor><calpain inhibitor><cardiac function><cardiac hypertrophy><cardiac injury><cardiac muscle><cardiac preservation><chemical structure function><chemical threat><circulatory system><compound optimization><design><designing><determine efficacy><developmental><drug/agent><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy study><evaluate efficacy><examine efficacy><excretion><formulation optimization><function of the heart><heart function><heart muscle><heart output><heart preservation><heavy metal Pb><heavy metal lead><hemodynamics><hepatic body system><hepatic organ system><improved><in vitro activity><in vivo><injuries><intracellular skeleton><intraperitoneal><kidney cell><lead optimization><lung edema><lung histology><lung injury><meter><model of animal><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mortality><novel><novel lead compound><parent><programs><pulmonary><pulmonary damage><pulmonary histology><pulmonary injury><pulmonary tissue damage><pulmonary tissue injury><renal><respiratory><response><safety study><structure function relationship><subcutaneous><subdermal><therapeutic agent development><therapeutic development><therapeutic lead compound><therapeutically effective><validations><weapons>
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Sonya Reid

RHODE ISLAND HOSPITAL, PROVIDENCE, RI

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$700,645
FY 2025

Project Title

The COVID-19 and Cancer Consortium (CCC19) Registry

Grant Number:

5U01CA287008-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary People with cancer have a higher risk of infections in general because of vulnerabilities arising from their cancer and its treatments. This is especially true for the novel coronavirus, SARS-CoV- 2. People with cancer are twice as likely to die from COVID-19 compared to the general ...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><21+ years old><Access to Care><Acute><Adrenal Cortex Hormones><Adult><Adult Human><Advanced Cancer><Advanced Malignant Neoplasm><Affect><Biometrics><Biometry><Biostatistics><Bladder Cancer><CCOP><COVID crisis><COVID epidemic><COVID pandemic><COVID survivors><COVID-19><COVID-19 affected><COVID-19 consequence><COVID-19 crisis><COVID-19 effect><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 impact><COVID-19 impacted><COVID-19 infection><COVID-19 infection survivors><COVID-19 pandemic><COVID-19 period><COVID-19 predisposition><COVID-19 public health crisis><COVID-19 survivors><COVID-19 susceptibility><COVID-19 therapy><COVID-19 treatment><COVID-19 virus><COVID-19 virus infection><COVID-19 vulnerability><COVID-19 years><COVID19 infection><COVID19 virus><CV-19><Cancer Prognosis><Cancer Treatment><Cancers><Caring><Case Study><Cause of Death><Cervical Cancer><Cervix Cancer><Clinical><CoV emergence><CoV-2><CoV2><Communicable Diseases><Communities><Community Clinical Oncology Program><Community Oncology><Community Practice><Comprehensive Cancer Center><Coronavirus Infectious Disease 2019><Coronavirus disease 2019 predisposition><Coronavirus disease 2019 susceptibility><Coronavirus disease 2019 vulnerability><Corticoids><Corticosteroids><Data><Data Coordinating Center><Data Coordination Center><Decision Making><Dedications><Diagnosis><Disease><Disease remission><Disorder><Drugs><Enrollment><Ethnic Origin><Ethnicity><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><General Population><General Public><Goals><Grawitz Tumor><Health Services Accessibility><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematopoietic Cancer><Heterogeneity><Histology><Hodgkin Disease><Hodgkin Disorder><Hodgkin lymphoma><Hodgkin's><Hodgkin's Lymphoma><Hodgkin's disease><Hodgkins lymphoma><Hospital Admission><Hospitalization><Hypernephroid Carcinoma><Hypernephroma><Immune mediated therapy><Immune system><Immunity><Immunocompromised><Immunocompromised Host><Immunocompromised Patient><Immunologically Directed Therapy><Immunosuppressed Host><Immunotherapy><Impairment><Infection><Infectious Diseases><Infectious Disorder><Insurance><Investigators><JAK-2><JAK2><JAK2 gene><JAK2 protein><Janus kinase 2><Journals><Knowledge><Lead><Magazine><Malignant Bladder Neoplasm><Malignant Cell><Malignant Cervical Neoplasm><Malignant Cervical Tumor><Malignant Hematologic Neoplasm><Malignant Lymphogranuloma><Malignant Melanoma><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasm of the Cervix><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Bladder><Malignant Tumor of the Cervix><Malignant Tumor of the Cervix Uteri><Malignant Tumor of the Lung><Malignant Uterine Cervix Neoplasm><Malignant Uterine Cervix Tumor><Malignant neoplasm of cervix uteri><Malignant neoplasm of lung><Malignant neoplasm of urinary bladder><Measurable><Measures><Medication><Melanoma><Methods><Minority><Modification><Morbidity><Morbidity - disease rate><Nephroid Carcinoma><North America><Oncology><Oncology Cancer><Outcome><Patients><Pb element><Persons><Pharmaceutical Preparations><Population><Predisposed to COVID-19><Predisposed to SARS-CoV-2><Predisposed to Severe acute respiratory syndrome coronavirus 2><Primary Infection><Process><Prognosis><Publishing><Pulmonary Cancer><Pulmonary malignant Neoplasm><Quality Control><Race><Races><Recurrent Malignant Neoplasm><Recurrent Malignant Tumor><Registries><Remission><Renal Adenocarcinoma><Renal Cell Adenocarcinoma><Renal Cell Cancer><Renal Cell Carcinoma><Reporting><Research><Research Design><Research Personnel><Researchers><Risk Factors><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 infection><SARS-CoV-2 pandemic><SARS-CoV-2 predisposition><SARS-CoV-2 survivors><SARS-CoV-2 susceptibility><SARS-CoV-2 therapy><SARS-CoV-2 treatment><SARS-CoV-2 vulnerability><SARS-CoV2><SARS-CoV2 infection><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Science><Screening for cancer><Secondary to><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 infection><Severe acute respiratory syndrome coronavirus 2 pandemic><Severe acute respiratory syndrome coronavirus 2 predisposition><Severe acute respiratory syndrome coronavirus 2 susceptibility><Severe acute respiratory syndrome coronavirus 2 vulnerability><Severe acute respiratory syndrome related corona virus 2><Site><Source><Study Type><Subgroup><Time><Tyrosine-Protein Kinase JAK2><Underrepresented Groups><Underrepresented Populations><United States><Urinary Bladder Cancer><Urinary Bladder Malignant Tumor><Uterine Cervix Cancer><Vaccination><Viral Respiratory Tract Infection><Wuhan coronavirus><access to health services><access to services><access to treatment><accessibility to health services><adulthood><anti-cancer therapy><anti-cancer treatment><availability of services><cancer care><cancer cell><cancer diagnosis><cancer progression><cancer recurrence><cancer therapy><cancer-directed therapy><care access><case report><cohort><corona virus emergence><coronavirus disease 2019><coronavirus disease 2019 consequence><coronavirus disease 2019 crisis><coronavirus disease 2019 effect><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 impact><coronavirus disease 2019 infection><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease 2019 therapy><coronavirus disease 2019 treatment><coronavirus disease 2019 virus><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19><coronavirus disease-19 global pandemic><coronavirus disease-19 impact><coronavirus disease-19 pandemic><coronavirus disease-19 virus><coronavirus emergence><coronavirus infectious disease-19><drug/agent><early cancer detection><emergent CoV><emergent corona virus><emergent coronavirus><emerging CoV><emerging corona virus><emerging coronavirus><end of life><end-of-life><enroll><esophagogastric cancer><experience><feature selection><future pandemic><gastroesophageal cancer><hCoV19><health service access><health services availability><heavy metal Pb><heavy metal lead><high risk><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunosuppressed patient><infected with COVID-19><infected with COVID19><infected with SARS-CoV-2><infected with SARS-CoV2><infected with coronavirus disease 2019><infected with severe acute respiratory syndrome coronavirus 2><infection risk><inhibitor><kidney adenocarcinoma><lung cancer><machine learned algorithm><machine learning algorithm><machine learning based algorithm><malignancy><meeting><meetings><mortality><nCoV><nCoV2><neoplasm progression><neoplasm/cancer><neoplastic progression><new CoV><new corona virus><new coronavirus><next pandemic><novel CoV><novel corona virus><novel coronavirus><operation><operations><pandemic><pandemic disease><predisposed to Coronavirus disease 2019><programs><racial><racial background><racial origin><recruit><response><screening cancer patients><service availability><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><severe acute respiratory syndrome coronavirus 2 therapy><severe acute respiratory syndrome coronavirus 2 treatment><socio-demographic factors><sociodemographic factors><study design><survive COVID-19><survive SARS-CoV-2><susceptible to COVID-19><susceptible to Coronavirus disease 2019><susceptible to SARS-CoV-2><susceptible to Severe acute respiratory syndrome coronavirus 2><treat COVID-19><treat SARS-CoV-2><treat coronavirus disease 2019><treat severe acute respiratory syndrome coronavirus 2><treatment access><tumor progression><under representation of groups><under represented groups><under represented people><under represented populations><under served community><underrepresentation of groups><underrepresented people><underserved community><viral respiratory infection><vulnerable to COVID-19><vulnerable to Coronavirus disease 2019><vulnerable to SARS-CoV-2><vulnerable to Severe acute respiratory syndrome coronavirus 2>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jeremy L. Warner

RHODE ISLAND HOSPITAL, PROVIDENCE, RI

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$700,645
FY 2025

Project Title

The COVID-19 and Cancer Consortium (CCC19) Registry

Grant Number:

5U01CA287008-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary People with cancer have a higher risk of infections in general because of vulnerabilities arising from their cancer and its treatments. This is especially true for the novel coronavirus, SARS-CoV- 2. People with cancer are twice as likely to die from COVID-19 compared to the general ...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><21+ years old><Access to Care><Acute><Adrenal Cortex Hormones><Adult><Adult Human><Advanced Cancer><Advanced Malignant Neoplasm><Affect><Biometrics><Biometry><Biostatistics><Bladder Cancer><CCOP><COVID crisis><COVID epidemic><COVID pandemic><COVID survivors><COVID-19><COVID-19 affected><COVID-19 consequence><COVID-19 crisis><COVID-19 effect><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 impact><COVID-19 impacted><COVID-19 infection><COVID-19 infection survivors><COVID-19 pandemic><COVID-19 period><COVID-19 predisposition><COVID-19 public health crisis><COVID-19 survivors><COVID-19 susceptibility><COVID-19 therapy><COVID-19 treatment><COVID-19 virus><COVID-19 virus infection><COVID-19 vulnerability><COVID-19 years><COVID19 infection><COVID19 virus><CV-19><Cancer Prognosis><Cancer Treatment><Cancers><Caring><Case Study><Cause of Death><Cervical Cancer><Cervix Cancer><Clinical><CoV emergence><CoV-2><CoV2><Communicable Diseases><Communities><Community Clinical Oncology Program><Community Oncology><Community Practice><Comprehensive Cancer Center><Coronavirus Infectious Disease 2019><Coronavirus disease 2019 predisposition><Coronavirus disease 2019 susceptibility><Coronavirus disease 2019 vulnerability><Corticoids><Corticosteroids><Data><Data Coordinating Center><Data Coordination Center><Decision Making><Dedications><Diagnosis><Disease><Disease remission><Disorder><Drugs><Enrollment><Ethnic Origin><Ethnicity><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><General Population><General Public><Goals><Grawitz Tumor><Health Services Accessibility><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematopoietic Cancer><Heterogeneity><Histology><Hodgkin Disease><Hodgkin Disorder><Hodgkin lymphoma><Hodgkin's><Hodgkin's Lymphoma><Hodgkin's disease><Hodgkins lymphoma><Hospital Admission><Hospitalization><Hypernephroid Carcinoma><Hypernephroma><Immune mediated therapy><Immune system><Immunity><Immunocompromised><Immunocompromised Host><Immunocompromised Patient><Immunologically Directed Therapy><Immunosuppressed Host><Immunotherapy><Impairment><Infection><Infectious Diseases><Infectious Disorder><Insurance><Investigators><JAK-2><JAK2><JAK2 gene><JAK2 protein><Janus kinase 2><Journals><Knowledge><Lead><Magazine><Malignant Bladder Neoplasm><Malignant Cell><Malignant Cervical Neoplasm><Malignant Cervical Tumor><Malignant Hematologic Neoplasm><Malignant Lymphogranuloma><Malignant Melanoma><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasm of the Cervix><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Bladder><Malignant Tumor of the Cervix><Malignant Tumor of the Cervix Uteri><Malignant Tumor of the Lung><Malignant Uterine Cervix Neoplasm><Malignant Uterine Cervix Tumor><Malignant neoplasm of cervix uteri><Malignant neoplasm of lung><Malignant neoplasm of urinary bladder><Measurable><Measures><Medication><Melanoma><Methods><Minority><Modification><Morbidity><Morbidity - disease rate><Nephroid Carcinoma><North America><Oncology><Oncology Cancer><Outcome><Patients><Pb element><Persons><Pharmaceutical Preparations><Population><Predisposed to COVID-19><Predisposed to SARS-CoV-2><Predisposed to Severe acute respiratory syndrome coronavirus 2><Primary Infection><Process><Prognosis><Publishing><Pulmonary Cancer><Pulmonary malignant Neoplasm><Quality Control><Race><Races><Recurrent Malignant Neoplasm><Recurrent Malignant Tumor><Registries><Remission><Renal Adenocarcinoma><Renal Cell Adenocarcinoma><Renal Cell Cancer><Renal Cell Carcinoma><Reporting><Research><Research Design><Research Personnel><Researchers><Risk Factors><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 infection><SARS-CoV-2 pandemic><SARS-CoV-2 predisposition><SARS-CoV-2 survivors><SARS-CoV-2 susceptibility><SARS-CoV-2 therapy><SARS-CoV-2 treatment><SARS-CoV-2 vulnerability><SARS-CoV2><SARS-CoV2 infection><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Science><Screening for cancer><Secondary to><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 infection><Severe acute respiratory syndrome coronavirus 2 pandemic><Severe acute respiratory syndrome coronavirus 2 predisposition><Severe acute respiratory syndrome coronavirus 2 susceptibility><Severe acute respiratory syndrome coronavirus 2 vulnerability><Severe acute respiratory syndrome related corona virus 2><Site><Source><Study Type><Subgroup><Time><Tyrosine-Protein Kinase JAK2><Underrepresented Groups><Underrepresented Populations><United States><Urinary Bladder Cancer><Urinary Bladder Malignant Tumor><Uterine Cervix Cancer><Vaccination><Viral Respiratory Tract Infection><Wuhan coronavirus><access to health services><access to services><access to treatment><accessibility to health services><adulthood><anti-cancer therapy><anti-cancer treatment><availability of services><cancer care><cancer cell><cancer diagnosis><cancer progression><cancer recurrence><cancer therapy><cancer-directed therapy><care access><case report><cohort><corona virus emergence><coronavirus disease 2019><coronavirus disease 2019 consequence><coronavirus disease 2019 crisis><coronavirus disease 2019 effect><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 impact><coronavirus disease 2019 infection><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease 2019 therapy><coronavirus disease 2019 treatment><coronavirus disease 2019 virus><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19><coronavirus disease-19 global pandemic><coronavirus disease-19 impact><coronavirus disease-19 pandemic><coronavirus disease-19 virus><coronavirus emergence><coronavirus infectious disease-19><drug/agent><early cancer detection><emergent CoV><emergent corona virus><emergent coronavirus><emerging CoV><emerging corona virus><emerging coronavirus><end of life><end-of-life><enroll><esophagogastric cancer><experience><feature selection><future pandemic><gastroesophageal cancer><hCoV19><health service access><health services availability><heavy metal Pb><heavy metal lead><high risk><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunosuppressed patient><infected with COVID-19><infected with COVID19><infected with SARS-CoV-2><infected with SARS-CoV2><infected with coronavirus disease 2019><infected with severe acute respiratory syndrome coronavirus 2><infection risk><inhibitor><kidney adenocarcinoma><lung cancer><machine learned algorithm><machine learning algorithm><machine learning based algorithm><malignancy><meeting><meetings><mortality><nCoV><nCoV2><neoplasm progression><neoplasm/cancer><neoplastic progression><new CoV><new corona virus><new coronavirus><next pandemic><novel CoV><novel corona virus><novel coronavirus><operation><operations><pandemic><pandemic disease><predisposed to Coronavirus disease 2019><programs><racial><racial background><racial origin><recruit><response><screening cancer patients><service availability><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><severe acute respiratory syndrome coronavirus 2 therapy><severe acute respiratory syndrome coronavirus 2 treatment><socio-demographic factors><sociodemographic factors><study design><survive COVID-19><survive SARS-CoV-2><susceptible to COVID-19><susceptible to Coronavirus disease 2019><susceptible to SARS-CoV-2><susceptible to Severe acute respiratory syndrome coronavirus 2><treat COVID-19><treat SARS-CoV-2><treat coronavirus disease 2019><treat severe acute respiratory syndrome coronavirus 2><treatment access><tumor progression><under representation of groups><under represented groups><under represented people><under represented populations><under served community><underrepresentation of groups><underrepresented people><underserved community><viral respiratory infection><vulnerable to COVID-19><vulnerable to Coronavirus disease 2019><vulnerable to SARS-CoV-2><vulnerable to Severe acute respiratory syndrome coronavirus 2>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

John D Ash

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$675,750
FY 2025

Project Title

Core Grant for Vision Research

Grant Number:

5P30EY008098-37

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

4/1/1997

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY – OVERALL COMPONENT This P30 renewal proposal requests continued funding to support the operation of six resource modules within the Vision Institute (VI) at Mercy Pavilion of the University of Pittsburgh. The VI provides a home base for the basic and clinical vision research for ~30 vision ...

Research Terms

<Area><Award><Biomechanics><Blindness><Cellular biology><Cities><Clinical><Collaborations><Communicable Diseases><Communities><Core Facility><Core Grant><Cornea><Creativeness><Dedications><Development><Environment><Equipment><Faculty><Faculty Recruitment><Floor><Fostering><Foundations><Funding><Generalized Growth><Glaucoma><Goals><Grant><Growth><Home><Hour><Human Resources><Image><Immunology><Infectious Diseases><Infectious Disorder><International><Investigators><Knowledge><Laboratories><Manpower><Methodology><NIH><Names><National Institutes of Health><Natural regeneration><Ophthalmology><Pilot Projects><Play><Postdoc><Postdoctoral Fellow><Productivity><Prosthesis><Prosthetic device><Prosthetics><Qualifying><R-Series Research Projects><R01 Mechanism><R01 Program><Regeneration><Request for Proposals><Research><Research Associate><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Research Training><Researchers><Resources><Retina><Role><Scientist><Services><Sight><Students><Technology><Tissue Growth><Trabecular Meshwork><Trabecular meshwork structure><Training><Training Programs><United States National Institutes of Health><Universities><Vision><Vision research><Visual><Work><base><bases><biomechanical><cell biology><cell regeneration><cellular regeneration><corneal><creativity><data deposition><data submission><developmental><experience><eye microbiome><glaucomatous><graduate student><homes><imaging><innovate><innovation><innovative><name><named><naming><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><ocular microbiome><ontogeny><operation><operations><personnel><pilot study><post-doc><post-doctoral><post-doctoral trainee><pre-doc><pre-doctoral><prevent><preventing><progenitor biology><progenitor cell based therapy><progenitor cell biology><progenitor cell therapy><progenitor cell treatment><progenitor therapy><progenitor treatment><programs><recruit><recruit teachers><regenerate><research and methods><research associates><research faculty><social role><stem and progenitor biology><stem and progenitor cell therapy><stem cell based therapy><stem cell biology><stem cell mediated therapy><stem cell therapeutics><stem cell therapy><stem cell treatment><stem cell-based therapeutic><stem cell-based treatment><student training><success><teacher recruitment><undergrad><undergraduate><undergraduate student><vision loss><vision science><visual function><visual loss><visual neuroscience><visual science>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amy S Kim

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$636,485
FY 2025

Project Title

Understanding Oral Diseases in Cystic Fibrosis to Develop Tailored Preventive Dental Interventions

Grant Number:

5U01DE030418-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/13/2021

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Abstract Cystic fibrosis (CF) is the most common life-limiting autosomal recessive disease in Caucasians. Impaired mucociliary clearance predisposes individuals with CF to chronic respiratory infections, resulting in progressive lung damage and premature death. We and others have shown that oral bac...

Research Terms

<12-20 years old><Address><Adolescence><Adolescent and Young Adult><Age><Airway health><Airway infections><Alabama><Bacteria><Behavior><Behavioral><Biologic Factor><Biological><Biological Factors><Buccal Cavity><Buccal Cavity Head and Neck><CF Preschoolers><CF lung disease><CF patients><Carbohydrates><Caries><Caring><Cariogenic Diet><Caucasian><Caucasian Race><Caucasians><Caucasoid><Caucasoid Race><Cavitas Oris><Cessation of life><Children with CF><Children's Hospital><Chronic><Clinical><Cystic Fibrosis><Data><Death><Dental><Dental Decay><Dental Hygiene><Dental Plaque><Dental caries><Dentistry><Dentists><Diagnostic><Disease><Disorder><Enrollment><Environment><Epidemiology><Evidence based intervention><FEV1><FEV1%VC><Forced Expiratory Volume 1 Test><Forced Expiratory Volume in 1 Second><General Population><General Public><Gingivitis><Health><Health behavior><Impairment><Incidence><Inflammatory><Intake><Intervention><Life><Life Expectancy><Link><Lung><Lung Diseases><Lung Respiratory System><Lung damage><Measures><Mechanical ventilation><Medical><Methods><Modeling><Modernization><Mouth><Mouth Diseases><Mouth microbiome><Mucociliary Clearance><Mucociliary Transport><Mucoviscidosis><North Carolina><Obstructive Lung Diseases><Occidental><Oral><Oral Cavity Disease><Oral Cavity Disorder><Oral Disease><Oral Disorder><Oral Hygiene><Oral cavity><Oral health><Outcome><PFT/FEV1><Pathogenicity><Pathway interactions><Patients><Pediatric Hospitals><Pneumonia><Population><Prevalence><Preventative dental care><Preventative dental service><Preventative intervention><Prevention><Preventive><Preventive dental care><Preventive dental service><Pulmonary Cystic Fibrosis><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Function Test/Forced Expiratory Volume 1><QOL><Quality of life><Reflux><Respiratory Infections><Respiratory Tract Infections><Risk><Risk Factors><S mutans><S. mutans><Saliva><Site><Source><Sputum><Standardization><Stomach><Streptococcus mutans><Time><Universities><Visit><Weight><adolescence (12-20)><age group><ages><analyze microbiome><aspirate><autosome><bacteria pathogen><bacterial pathogen><biologic><children with cystic fibrosis><cohort><cystic fibrosis lung><cystic fibrosis lung disease><cystic fibrosis patients><cystic fibrosis preschoolers><decline in function><decline in functional status><dental health><disease of the lung><disease prevention><disorder of the lung><disorder prevention><dysbacteriosis><dysbiosis><dysbiotic><early adolescence><enroll><epidemiologic><epidemiological><functional decline><functional status decline><gastric><health related behavior><high risk><improved><individuals with CF><individuals with cystic fibrosis><intervention for prevention><loss of function><lung disorder><lung function><lung function decline><lung injury><lung microbiome><mechanical respiratory assist><mechanically ventilated><microbial imbalance><microbiome><microbiome analysis><mouth disorder><obstructive pulmonary diseases><oral bacteria><oral flora><oral microbiome><pathogenic bacteria><pathway><patients with CF><patients with cystic fibrosis><pediatric cystic fibrosis><peer><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><prospective><pulmonary><pulmonary damage><pulmonary function><pulmonary function decline><pulmonary injury><pulmonary microbiome><pulmonary tissue damage><pulmonary tissue injury><randomized, clinical trials><respiratory><respiratory health><tooth decay><weights><white race>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Margaret Rosenfeld

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$636,485
FY 2025

Project Title

Understanding Oral Diseases in Cystic Fibrosis to Develop Tailored Preventive Dental Interventions

Grant Number:

5U01DE030418-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/13/2021

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Abstract Cystic fibrosis (CF) is the most common life-limiting autosomal recessive disease in Caucasians. Impaired mucociliary clearance predisposes individuals with CF to chronic respiratory infections, resulting in progressive lung damage and premature death. We and others have shown that oral bac...

Research Terms

<12-20 years old><Address><Adolescence><Adolescent and Young Adult><Age><Airway health><Airway infections><Alabama><Bacteria><Behavior><Behavioral><Biologic Factor><Biological><Biological Factors><Buccal Cavity><Buccal Cavity Head and Neck><CF Preschoolers><CF lung disease><CF patients><Carbohydrates><Caries><Caring><Cariogenic Diet><Caucasian><Caucasian Race><Caucasians><Caucasoid><Caucasoid Race><Cavitas Oris><Cessation of life><Children with CF><Children's Hospital><Chronic><Clinical><Cystic Fibrosis><Data><Death><Dental><Dental Decay><Dental Hygiene><Dental Plaque><Dental caries><Dentistry><Dentists><Diagnostic><Disease><Disorder><Enrollment><Environment><Epidemiology><Evidence based intervention><FEV1><FEV1%VC><Forced Expiratory Volume 1 Test><Forced Expiratory Volume in 1 Second><General Population><General Public><Gingivitis><Health><Health behavior><Impairment><Incidence><Inflammatory><Intake><Intervention><Life><Life Expectancy><Link><Lung><Lung Diseases><Lung Respiratory System><Lung damage><Measures><Mechanical ventilation><Medical><Methods><Modeling><Modernization><Mouth><Mouth Diseases><Mouth microbiome><Mucociliary Clearance><Mucociliary Transport><Mucoviscidosis><North Carolina><Obstructive Lung Diseases><Occidental><Oral><Oral Cavity Disease><Oral Cavity Disorder><Oral Disease><Oral Disorder><Oral Hygiene><Oral cavity><Oral health><Outcome><PFT/FEV1><Pathogenicity><Pathway interactions><Patients><Pediatric Hospitals><Pneumonia><Population><Prevalence><Preventative dental care><Preventative dental service><Preventative intervention><Prevention><Preventive><Preventive dental care><Preventive dental service><Pulmonary Cystic Fibrosis><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Function Test/Forced Expiratory Volume 1><QOL><Quality of life><Reflux><Respiratory Infections><Respiratory Tract Infections><Risk><Risk Factors><S mutans><S. mutans><Saliva><Site><Source><Sputum><Standardization><Stomach><Streptococcus mutans><Time><Universities><Visit><Weight><adolescence (12-20)><age group><ages><analyze microbiome><aspirate><autosome><bacteria pathogen><bacterial pathogen><biologic><children with cystic fibrosis><cohort><cystic fibrosis lung><cystic fibrosis lung disease><cystic fibrosis patients><cystic fibrosis preschoolers><decline in function><decline in functional status><dental health><disease of the lung><disease prevention><disorder of the lung><disorder prevention><dysbacteriosis><dysbiosis><dysbiotic><early adolescence><enroll><epidemiologic><epidemiological><functional decline><functional status decline><gastric><health related behavior><high risk><improved><individuals with CF><individuals with cystic fibrosis><intervention for prevention><loss of function><lung disorder><lung function><lung function decline><lung injury><lung microbiome><mechanical respiratory assist><mechanically ventilated><microbial imbalance><microbiome><microbiome analysis><mouth disorder><obstructive pulmonary diseases><oral bacteria><oral flora><oral microbiome><pathogenic bacteria><pathway><patients with CF><patients with cystic fibrosis><pediatric cystic fibrosis><peer><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><prospective><pulmonary><pulmonary damage><pulmonary function><pulmonary function decline><pulmonary injury><pulmonary microbiome><pulmonary tissue damage><pulmonary tissue injury><randomized, clinical trials><respiratory><respiratory health><tooth decay><weights><white race>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARK E. LOWE

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$635,299
FY 2025

Project Title

INSPPIRE: Using the natural history of pediatric chronic pancreatitis to identify disease predictors and design therapies

Grant Number:

2U01DK108334-11

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/28/2015

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Pediatric acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) are rare, but highly burdensome diseases without a cure. ARP progresses to CP complicated by pain, exocrine pancreatic insufficiency (EPI), and diabetes mellitus (DM). Few studies have been performed to chara...

Research Terms

<0-11 years old><21+ years old><Abdominal Pain><Acute><Address><Adult><Adult Human><Anatomic Sites><Anatomic structures><Anatomy><Ancillary Study><Autoantibodies><Beta Cell><Biological Markers><Blood Plasma><CF Preschoolers><Causality><Child><Child Youth><Childhood><Children (0-21)><Children with CF><Clinical><Clinical Trials><Cognition Therapy><Cognitive Psychotherapy><Cognitive Therapy><Cognitive treatment><Computerized Medical Record><Cystic Fibrosis><DNA mutation><Data><Data Collection><Demographic Impact><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Progression><Disorder><ED visit><ER visit><Electronic Medical Record><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Enrollment><Environmental Factor><Environmental Risk Factor><Etiology><Exocrine pancreatic insufficiency><Family><Genetic><Genetic Change><Genetic Risk><Genetic defect><Genetic mutation><Health Care><Health Care Costs><Health Care Systems><Health Costs><Hospital Admission><Hospitalization><Insulin Cell><Insulin Secreting Cell><Interdisciplinary Research><Interdisciplinary Study><International><Intervention><Lead><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Malignant Pancreatic Neoplasm><Malignant neoplasm of pancreas><Mediator><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Membrane><Mucoviscidosis><Multidisciplinary Collaboration><Multidisciplinary Research><Mutation><NMR Imaging><NMR Tomography><Natural History><Nuclear Magnetic Resonance Imaging><Operative Procedures><Operative Surgical Procedures><Organ failure><Outcome><Pain><Painful><Pancreas><Pancreas Cancer><Pancreatic><Pancreatic Cancer><Pancreatic Insufficiency><Pancreatic enzyme><Pancreatitis><Participant><Pb element><Phenotype><Placebos><Plasma><Plasma Serum><Publications><QOL><Quality of life><Randomized><Reporting><Research Resources><Resources><Reticuloendothelial System, Serum, Plasma><Risk Factors><Risk-associated variant><Schools><Science><Scientific Publication><Sham Treatment><Surgical><Surgical Interventions><Surgical Procedure><Testing><Time><Variant><Variation><Zeugmatography><adulthood><analyzing longitudinal><autoimmune antibody><autoreactive antibody><bio-markers><biologic marker><biomarker><biomarker development><causation><children with cystic fibrosis><chronic pancreatitis><cognitive behavior intervention><cognitive behavior modification><cognitive behavior therapy><cognitive behavioral intervention><cognitive behavioral modification><cognitive behavioral therapy><cognitive behavioral treatment><cohort><cost><cystic fibrosis preschoolers><developmental><diabetes><disease causation><drug repositioning><drug repurposing><effective intervention><efficacy testing><enroll><environmental risk><genome mutation><health related quality of life><heavy metal Pb><heavy metal lead><imaging biomarker><imaging marker><imaging study><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><innovate><innovation><innovative><intervention design><kids><long-term study><longitudinal analysis><longitudinal outcome studies><membrane structure><novel><pancreas enzyme><pancreatic malignancy><pediatric><pediatric cystic fibrosis><prevent><preventing><prognostic><prospective><randomisation><randomization><randomly assigned><recruit><recurrent pancreatitis><repurposing agent><repurposing medication><response to therapy><response to treatment><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><self reactive antibody><sham therapy><surgery><telehealth><therapeutic response><therapy design><therapy response><tool><treatment design><treatment response><treatment responsiveness><work group><working group><younger age><youngster><β-cell><β-cells><βCell>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Aliye Uc

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$635,299
FY 2025

Project Title

INSPPIRE: Using the natural history of pediatric chronic pancreatitis to identify disease predictors and design therapies

Grant Number:

2U01DK108334-11

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/28/2015

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Pediatric acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) are rare, but highly burdensome diseases without a cure. ARP progresses to CP complicated by pain, exocrine pancreatic insufficiency (EPI), and diabetes mellitus (DM). Few studies have been performed to chara...

Research Terms

<0-11 years old><21+ years old><Abdominal Pain><Acute><Address><Adult><Adult Human><Anatomic Sites><Anatomic structures><Anatomy><Ancillary Study><Autoantibodies><Beta Cell><Biological Markers><Blood Plasma><CF Preschoolers><Causality><Child><Child Youth><Childhood><Children (0-21)><Children with CF><Clinical><Clinical Trials><Cognition Therapy><Cognitive Psychotherapy><Cognitive Therapy><Cognitive treatment><Computerized Medical Record><Cystic Fibrosis><DNA mutation><Data><Data Collection><Demographic Impact><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Progression><Disorder><ED visit><ER visit><Electronic Medical Record><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Enrollment><Environmental Factor><Environmental Risk Factor><Etiology><Exocrine pancreatic insufficiency><Family><Genetic><Genetic Change><Genetic Risk><Genetic defect><Genetic mutation><Health Care><Health Care Costs><Health Care Systems><Health Costs><Hospital Admission><Hospitalization><Insulin Cell><Insulin Secreting Cell><Interdisciplinary Research><Interdisciplinary Study><International><Intervention><Lead><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Malignant Pancreatic Neoplasm><Malignant neoplasm of pancreas><Mediator><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Membrane><Mucoviscidosis><Multidisciplinary Collaboration><Multidisciplinary Research><Mutation><NMR Imaging><NMR Tomography><Natural History><Nuclear Magnetic Resonance Imaging><Operative Procedures><Operative Surgical Procedures><Organ failure><Outcome><Pain><Painful><Pancreas><Pancreas Cancer><Pancreatic><Pancreatic Cancer><Pancreatic Insufficiency><Pancreatic enzyme><Pancreatitis><Participant><Pb element><Phenotype><Placebos><Plasma><Plasma Serum><Publications><QOL><Quality of life><Randomized><Reporting><Research Resources><Resources><Reticuloendothelial System, Serum, Plasma><Risk Factors><Risk-associated variant><Schools><Science><Scientific Publication><Sham Treatment><Surgical><Surgical Interventions><Surgical Procedure><Testing><Time><Variant><Variation><Zeugmatography><adulthood><analyzing longitudinal><autoimmune antibody><autoreactive antibody><bio-markers><biologic marker><biomarker><biomarker development><causation><children with cystic fibrosis><chronic pancreatitis><cognitive behavior intervention><cognitive behavior modification><cognitive behavior therapy><cognitive behavioral intervention><cognitive behavioral modification><cognitive behavioral therapy><cognitive behavioral treatment><cohort><cost><cystic fibrosis preschoolers><developmental><diabetes><disease causation><drug repositioning><drug repurposing><effective intervention><efficacy testing><enroll><environmental risk><genome mutation><health related quality of life><heavy metal Pb><heavy metal lead><imaging biomarker><imaging marker><imaging study><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><innovate><innovation><innovative><intervention design><kids><long-term study><longitudinal analysis><longitudinal outcome studies><membrane structure><novel><pancreas enzyme><pancreatic malignancy><pediatric><pediatric cystic fibrosis><prevent><preventing><prognostic><prospective><randomisation><randomization><randomly assigned><recruit><recurrent pancreatitis><repurposing agent><repurposing medication><response to therapy><response to treatment><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><self reactive antibody><sham therapy><surgery><telehealth><therapeutic response><therapy design><therapy response><tool><treatment design><treatment response><treatment responsiveness><work group><working group><younger age><youngster><β-cell><β-cells><βCell>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jeong Ho Kim

TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, COLLEGE STATION, TX

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$630,836
FY 2025

Project Title

Commercial Fishing Occupational Safety Research Cooperative Agreement (U01) - 2022

Grant Number:

1U01OH012968-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

ALLCDC

Start Date:

9/1/2023

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JAMES P. LASH

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$629,766
FY 2025

Project Title

University of Illinois at Chicago KPMP CKD Recruitment Site

Grant Number:

5U01DK133081-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Chronic kidney disease (CKD) is a major public health problem in the United States that affects 37 million Americans and disproportionately burdens racial and ethnic minority populations. Advances in personalized medicine approaches for patients with CKD lag behind advances in other fields. Current ...

Research Terms

<21+ years old><Active Follow-up><Address><Adopted><Adult><Adult Human><Affect><Algorithms><American><Atlases><Benefits and Risks><Bioethicist><Bioethics><Bioethics Consultants><Biomedical Ethics><Biometrics><Biometry><Biostatistics><Black><Black race><Cancers><Characteristics><Chicago><Chronic Kidney Failure><Chronic Kidney Insufficiency><Chronic Renal Disease><Chronic Renal Failure><Chronic Renal Insufficiency><Classification><Clinic Visits><Clinical><Cohort Studies><Collaborations><Communities><Concurrent Studies><Coupling><Data><Data Collection><Development><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disease Progression><Disorder><Economics><Electronic Health Record><Eligibility><Eligibility Determination><Enrollment><Ensure><Ethics><Evaluation><Federally Qualified Health Center><Glomerular Filtration Rate><Goals><Health><Health Care Systems><Health Sciences><Heterogeneity><Hispanic><Illinois><Individual><Infrastructure><Interventional radiology><Interview><Investigators><Kidney><Kidney Diseases><Kidney Urinary System><Letters><Link><Longitudinal Studies><Malignant Neoplasms><Malignant Tumor><Measures><Methods><Mission><Musculoskeletal Pain Disorder><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Neighborhoods><Nephrology><Nephropathy><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Ontology><Outcome><Participant><Pathology><Patients><Persons><Phenotype><Phone><Play><Population Heterogeneity><Prevention><Proteinuria><Protocol><Protocol Screening><Protocols documentation><Public Health><Renal Disease><Reporting><Research><Research Personnel><Researchers><Rheumatic Diseases><Rheumatism><Rheumatologic Diseases><Rheumatologic Disorder><Role><Site><Structure><System><Systematics><Telephone><Time><Underrepresented Ethnic Minority><Underrepresented Minority><United States><Universities><Visit><Work><active followup><adulthood><built environment><career><chronic kidney disease><clinical center><clinical phenotype><cohort><community advisory board><community advisory committee><community advisory panel><developmental><disease heterogeneity><disease subgroups><disease subtype><disorder subtype><diverse populations><economic><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><ethical><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><experience><follow up><follow-up><followed up><followup><heterogeneous population><improved><inclusion criteria><insight><interest><kidney biopsy><kidney disorder><long-term study><longitudinal outcome studies><malignancy><meeting><meetings><molecular phenotype><multidisciplinary><neoplasm/cancer><participant engagement><patient centered><patient engagement><patient oriented><patient population><patient portal><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><phenotypic data><population diversity><precision medicine><precision-based medicine><primary care provider><providers from primary care><providers of primary care><racial minority group><racial minority individual><racial minority people><racial minority population><recruit><renal><renal biopsy><renal disorder><retention rate><retention strategy><social><social health determinants><social role><under-representation of minorities><under-represented minority><underrepresentation of minorities><work group><working group>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ana Catherine Ricardo

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$629,766
FY 2025

Project Title

University of Illinois at Chicago KPMP CKD Recruitment Site

Grant Number:

5U01DK133081-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Chronic kidney disease (CKD) is a major public health problem in the United States that affects 37 million Americans and disproportionately burdens racial and ethnic minority populations. Advances in personalized medicine approaches for patients with CKD lag behind advances in other fields. Current ...

Research Terms

<21+ years old><Active Follow-up><Address><Adopted><Adult><Adult Human><Affect><Algorithms><American><Atlases><Benefits and Risks><Bioethicist><Bioethics><Bioethics Consultants><Biomedical Ethics><Biometrics><Biometry><Biostatistics><Black><Black race><Cancers><Characteristics><Chicago><Chronic Kidney Failure><Chronic Kidney Insufficiency><Chronic Renal Disease><Chronic Renal Failure><Chronic Renal Insufficiency><Classification><Clinic Visits><Clinical><Cohort Studies><Collaborations><Communities><Concurrent Studies><Coupling><Data><Data Collection><Development><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disease Progression><Disorder><Economics><Electronic Health Record><Eligibility><Eligibility Determination><Enrollment><Ensure><Ethics><Evaluation><Federally Qualified Health Center><Glomerular Filtration Rate><Goals><Health><Health Care Systems><Health Sciences><Heterogeneity><Hispanic><Illinois><Individual><Infrastructure><Interventional radiology><Interview><Investigators><Kidney><Kidney Diseases><Kidney Urinary System><Letters><Link><Longitudinal Studies><Malignant Neoplasms><Malignant Tumor><Measures><Methods><Mission><Musculoskeletal Pain Disorder><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Neighborhoods><Nephrology><Nephropathy><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Ontology><Outcome><Participant><Pathology><Patients><Persons><Phenotype><Phone><Play><Population Heterogeneity><Prevention><Proteinuria><Protocol><Protocol Screening><Protocols documentation><Public Health><Renal Disease><Reporting><Research><Research Personnel><Researchers><Rheumatic Diseases><Rheumatism><Rheumatologic Diseases><Rheumatologic Disorder><Role><Site><Structure><System><Systematics><Telephone><Time><Underrepresented Ethnic Minority><Underrepresented Minority><United States><Universities><Visit><Work><active followup><adulthood><built environment><career><chronic kidney disease><clinical center><clinical phenotype><cohort><community advisory board><community advisory committee><community advisory panel><developmental><disease heterogeneity><disease subgroups><disease subtype><disorder subtype><diverse populations><economic><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><ethical><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><experience><follow up><follow-up><followed up><followup><heterogeneous population><improved><inclusion criteria><insight><interest><kidney biopsy><kidney disorder><long-term study><longitudinal outcome studies><malignancy><meeting><meetings><molecular phenotype><multidisciplinary><neoplasm/cancer><participant engagement><patient centered><patient engagement><patient oriented><patient population><patient portal><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><phenotypic data><population diversity><precision medicine><precision-based medicine><primary care provider><providers from primary care><providers of primary care><racial minority group><racial minority individual><racial minority people><racial minority population><recruit><renal><renal biopsy><renal disorder><retention rate><retention strategy><social><social health determinants><social role><under-representation of minorities><under-represented minority><underrepresentation of minorities><work group><working group>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yong Chen

UNIVERSITY OF CALIFORNIA-IRVINE, IRVINE, CA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$602,581
FY 2025

Project Title

3D In vivo dosimetry for FLASH proton therapy

Grant Number:

5U01CA288351-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/12/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT: This U01 application aims to (1) develop a robust protoacoustic dosimeter for 3D in vivo dosimetry in proton FLASH therapy, which is essential for its clinical application and acceptance; (2) form a multi-disciplinary and multi-institutional research partnership, incorporating both academi...

Research Terms

<21+ years old><3-D><3-Dimensional><3D><Acceleration><Acoustics><Acute Radiation Syndrome><Address><Adoption><Adult><Adult Human><Affect><Anatomic Sites><Anatomic structures><Anatomy><Animal Model><Animal Models and Related Studies><Area><Body Tissues><Cancer Patient><Cancers><Cause of Death><Cell Communication and Signaling><Cell Signaling><Clinical><Collaborations><Computer Simulation><Computer based Simulation><Data><Deposit><Deposition><Development><Dose><Dose Rate><Echography><Echotomography><Effectiveness><Engineering><Ensure><Film><General Radiology><Generalized Growth><Goals><Grant><Growth><H+ element><Human><Hydrogen Ions><IVIS SpectrumCT><IVIS imaging><IVIS optical imaging><IVIS spectral imaging><IVIS spectrum><IVIS system><Image><Image Enhancement><Imaging Procedures><Imaging Technics><Imaging Techniques><Industrialization><Industry><Institution><Intracellular Communication and Signaling><Investigation><Ions><Malignant Neoplasms><Malignant Tumor><Measurement><Medical Ultrasound><Methods><Modality><Modern Man><Normal Tissue><Normal tissue morphology><Organ><Outcome><Patients><Performance><Physiologic pulse><Position><Positioning Attribute><Protons><Public Health><Publications><Pulse><Radiation><Radiation Dosimetry><Radiation Toxicity><Radiation therapy><Radiology><Radiology Specialty><Radiometry><Radiotherapeutics><Radiotherapy><Radiotoxicity><Research><Resolution><Scientific Publication><Signal Transduction><Signal Transduction Systems><Signaling><System><Techniques><Technology><Testing><Tissue Growth><Tissues><Toxic effect><Toxicities><Transducers><Translations><Treatment-related toxicity><Ultrasonic Imaging><Ultrasonogram><Ultrasonography><Ultrasound Diagnosis><Ultrasound Medical Imaging><Ultrasound Test><Uncertainty><Validation><Work><acoustic imaging><adulthood><biological signal transduction><clinical applicability><clinical application><computational simulation><computerized simulation><data acquisition><data acquisitions><design><designing><detector><developmental><diagnostic ultrasound><dose information><dosimetry><dosimetry imaging><doubt><experience><experiment><experimental research><experimental study><experiments><high risk><image construction><image generation><image reconstruction><image-based method><imaging><imaging capabilities><imaging method><imaging modality><imaging system><in vivo><in vivo Model><in vivo imaging system><indexing><industrial partnership><industry partner><industry partnership><innovate><innovation><innovative><interest><malignancy><mechanical properties><model of animal><multidisciplinary><neoplasm/cancer><novel><ontogeny><phantom model><physical property><proton beam><proton therapy><prototype><radiation poisoning><radiation treatment><radioassay><real-time images><realtime image><resolutions><simulation><sonogram><sonography><sound measurement><stem><success><temporal measurement><temporal resolution><therapeutic toxicity><therapy associated toxicity><therapy related toxicity><therapy toxicity><three dimensional><time measurement><translation><treatment toxicity><treatment with radiation><treatment-associated toxicity><tumor><ultrasound><ultrasound imaging><ultrasound scanning><validations>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lei Ren

UNIVERSITY OF CALIFORNIA-IRVINE, IRVINE, CA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$602,581
FY 2025

Project Title

3D In vivo dosimetry for FLASH proton therapy

Grant Number:

5U01CA288351-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/12/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT: This U01 application aims to (1) develop a robust protoacoustic dosimeter for 3D in vivo dosimetry in proton FLASH therapy, which is essential for its clinical application and acceptance; (2) form a multi-disciplinary and multi-institutional research partnership, incorporating both academi...

Research Terms

<21+ years old><3-D><3-Dimensional><3D><Acceleration><Acoustics><Acute Radiation Syndrome><Address><Adoption><Adult><Adult Human><Affect><Anatomic Sites><Anatomic structures><Anatomy><Animal Model><Animal Models and Related Studies><Area><Body Tissues><Cancer Patient><Cancers><Cause of Death><Cell Communication and Signaling><Cell Signaling><Clinical><Collaborations><Computer Simulation><Computer based Simulation><Data><Deposit><Deposition><Development><Dose><Dose Rate><Echography><Echotomography><Effectiveness><Engineering><Ensure><Film><General Radiology><Generalized Growth><Goals><Grant><Growth><H+ element><Human><Hydrogen Ions><IVIS SpectrumCT><IVIS imaging><IVIS optical imaging><IVIS spectral imaging><IVIS spectrum><IVIS system><Image><Image Enhancement><Imaging Procedures><Imaging Technics><Imaging Techniques><Industrialization><Industry><Institution><Intracellular Communication and Signaling><Investigation><Ions><Malignant Neoplasms><Malignant Tumor><Measurement><Medical Ultrasound><Methods><Modality><Modern Man><Normal Tissue><Normal tissue morphology><Organ><Outcome><Patients><Performance><Physiologic pulse><Position><Positioning Attribute><Protons><Public Health><Publications><Pulse><Radiation><Radiation Dosimetry><Radiation Toxicity><Radiation therapy><Radiology><Radiology Specialty><Radiometry><Radiotherapeutics><Radiotherapy><Radiotoxicity><Research><Resolution><Scientific Publication><Signal Transduction><Signal Transduction Systems><Signaling><System><Techniques><Technology><Testing><Tissue Growth><Tissues><Toxic effect><Toxicities><Transducers><Translations><Treatment-related toxicity><Ultrasonic Imaging><Ultrasonogram><Ultrasonography><Ultrasound Diagnosis><Ultrasound Medical Imaging><Ultrasound Test><Uncertainty><Validation><Work><acoustic imaging><adulthood><biological signal transduction><clinical applicability><clinical application><computational simulation><computerized simulation><data acquisition><data acquisitions><design><designing><detector><developmental><diagnostic ultrasound><dose information><dosimetry><dosimetry imaging><doubt><experience><experiment><experimental research><experimental study><experiments><high risk><image construction><image generation><image reconstruction><image-based method><imaging><imaging capabilities><imaging method><imaging modality><imaging system><in vivo><in vivo Model><in vivo imaging system><indexing><industrial partnership><industry partner><industry partnership><innovate><innovation><innovative><interest><malignancy><mechanical properties><model of animal><multidisciplinary><neoplasm/cancer><novel><ontogeny><phantom model><physical property><proton beam><proton therapy><prototype><radiation poisoning><radiation treatment><radioassay><real-time images><realtime image><resolutions><simulation><sonogram><sonography><sound measurement><stem><success><temporal measurement><temporal resolution><therapeutic toxicity><therapy associated toxicity><therapy related toxicity><therapy toxicity><three dimensional><time measurement><translation><treatment toxicity><treatment with radiation><treatment-associated toxicity><tumor><ultrasound><ultrasound imaging><ultrasound scanning><validations>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Shawn Liangzhong Xiang

UNIVERSITY OF CALIFORNIA-IRVINE, IRVINE, CA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$602,581
FY 2025

Project Title

3D In vivo dosimetry for FLASH proton therapy

Grant Number:

5U01CA288351-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/12/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT: This U01 application aims to (1) develop a robust protoacoustic dosimeter for 3D in vivo dosimetry in proton FLASH therapy, which is essential for its clinical application and acceptance; (2) form a multi-disciplinary and multi-institutional research partnership, incorporating both academi...

Research Terms

<21+ years old><3-D><3-Dimensional><3D><Acceleration><Acoustics><Acute Radiation Syndrome><Address><Adoption><Adult><Adult Human><Affect><Anatomic Sites><Anatomic structures><Anatomy><Animal Model><Animal Models and Related Studies><Area><Body Tissues><Cancer Patient><Cancers><Cause of Death><Cell Communication and Signaling><Cell Signaling><Clinical><Collaborations><Computer Simulation><Computer based Simulation><Data><Deposit><Deposition><Development><Dose><Dose Rate><Echography><Echotomography><Effectiveness><Engineering><Ensure><Film><General Radiology><Generalized Growth><Goals><Grant><Growth><H+ element><Human><Hydrogen Ions><IVIS SpectrumCT><IVIS imaging><IVIS optical imaging><IVIS spectral imaging><IVIS spectrum><IVIS system><Image><Image Enhancement><Imaging Procedures><Imaging Technics><Imaging Techniques><Industrialization><Industry><Institution><Intracellular Communication and Signaling><Investigation><Ions><Malignant Neoplasms><Malignant Tumor><Measurement><Medical Ultrasound><Methods><Modality><Modern Man><Normal Tissue><Normal tissue morphology><Organ><Outcome><Patients><Performance><Physiologic pulse><Position><Positioning Attribute><Protons><Public Health><Publications><Pulse><Radiation><Radiation Dosimetry><Radiation Toxicity><Radiation therapy><Radiology><Radiology Specialty><Radiometry><Radiotherapeutics><Radiotherapy><Radiotoxicity><Research><Resolution><Scientific Publication><Signal Transduction><Signal Transduction Systems><Signaling><System><Techniques><Technology><Testing><Tissue Growth><Tissues><Toxic effect><Toxicities><Transducers><Translations><Treatment-related toxicity><Ultrasonic Imaging><Ultrasonogram><Ultrasonography><Ultrasound Diagnosis><Ultrasound Medical Imaging><Ultrasound Test><Uncertainty><Validation><Work><acoustic imaging><adulthood><biological signal transduction><clinical applicability><clinical application><computational simulation><computerized simulation><data acquisition><data acquisitions><design><designing><detector><developmental><diagnostic ultrasound><dose information><dosimetry><dosimetry imaging><doubt><experience><experiment><experimental research><experimental study><experiments><high risk><image construction><image generation><image reconstruction><image-based method><imaging><imaging capabilities><imaging method><imaging modality><imaging system><in vivo><in vivo Model><in vivo imaging system><indexing><industrial partnership><industry partner><industry partnership><innovate><innovation><innovative><interest><malignancy><mechanical properties><model of animal><multidisciplinary><neoplasm/cancer><novel><ontogeny><phantom model><physical property><proton beam><proton therapy><prototype><radiation poisoning><radiation treatment><radioassay><real-time images><realtime image><resolutions><simulation><sonogram><sonography><sound measurement><stem><success><temporal measurement><temporal resolution><therapeutic toxicity><therapy associated toxicity><therapy related toxicity><therapy toxicity><three dimensional><time measurement><translation><treatment toxicity><treatment with radiation><treatment-associated toxicity><tumor><ultrasound><ultrasound imaging><ultrasound scanning><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Braden Kuo

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$600,926
FY 2025

Project Title

A Consortium for Gut-Brain Communication in Parkinson's Disease

Grant Number:

5U01DK140933-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract We plan to initiate participation in the NIH U01 Consortium for Gut-Brain Communication in Parkinson’s Disease (PD) (GBPDC) including contribution of PD patients across the spectrum of disease, with and without GI symptoms and age/sex matched healthy controls into the regist...

Research Terms

<Affect><Age><Alimentary Canal><Amaze><Brain><Brain Nervous System><Brain Stem><Brainstem><CNS Nervous System><Caring><Cell Communication and Signaling><Cell Signaling><Central Nervous System><Characteristics><Circadian Dysregulation><Circadian Rhythms><Clinical><Clinical Research><Clinical Study><Clinical Treatment><Collection><Colon><DA Neuron><Data><Degenerative Neurologic Disorders><Dependence><Deterioration><Digestive Tract><Disease><Disorder><Dopamine neuron><Drugs><Dysfunction><Dyskinesia Syndromes><Emesis><Encephalon><Enteral><Enteric><Functional MRI><Functional Magnetic Resonance Imaging><Functional disorder><GI Tract><Gamma Camera Imaging><Gastric Stasis><Gastrointestinal Diseases><Gastrointestinal Tract><Gastrointestinal tract structure><Gastroparesis><General Hospitals><Goals><Health><Hour><Human><Image><Inpatients><Intracellular Communication and Signaling><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Massachusetts><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Melatonin><Modern Man><Motility><Movement Disorder Syndromes><Movement Disorders><NAC precursor><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Nausea><Nerve><Nervous System><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neuraxis><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Body System><Neurologic Degenerative Conditions><Neurologic Organ System><Nuclear Magnetic Resonance Imaging><Nyctohemeral Rhythm><Outcome><PARK1 protein><PARK4 protein><Paralysis Agitans><Parkinson><Parkinson Disease><Participant><Pathologic><Pathologic Processes><Pathological Processes><Patient Recruitments><Patient Selection><Patient Self-Report><Patients><Pattern><Peripheral><Pharmaceutical Preparations><Phenotype><Physiology><Physiopathology><Polysomnography><Population><Primary Parkinsonism><QOL><Quality of life><Questionnaires><Radioisotope Scanning><Radionuclide Imaging><Registries><Reporting><Research><SNCA><SNCA protein><Scintigraphy><Self-Report><Signal Transduction><Signal Transduction Systems><Signaling><Site><Sleep><Sleep Disorders><Sleep Monitoring><Sleep disturbances><Somnography><Stomach><Substantia Nigra><Substantia nigra structure><Symptoms><System><Testing><Thick><Thickness><Twenty-Four Hour Rhythm><United States National Institutes of Health><Vomiting><Zeugmatography><a-syn><a-synuclein><aberrant sleep><absorption><actigraph><actigraphy><ages><alimentary tract><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><biological signal transduction><circadian><circadian abnormality><circadian disruption><circadian disturbance><circadian dysfunction><circadian impairment><circadian process><circadian rhythmicity><clinical intervention><clinical therapy><cohort><daily biorhythm><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><delayed gastric emptying><digestive canal><disease control><disorder control><disrupted sleep><disturbed sleep><dopaminergic neuron><drug/agent><dysmotility><dysmotility syndrome><experience><fMRI><gastric><gastrointestinal disorder><gastrointestinal function><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><imaging><impaired sleep><innovate><innovation><innovative><irregular sleep><microbiome><motility disorder><motor deficit><neural circuit><neural circuitry><neurocircuitry><neurodegenerative illness><non A-beta component of AD amyloid><non A4 component of amyloid precursor><participant recruitment><pathophysiology><patient population><poor sleep><potential biological marker><potential biomarker><quality of sleep><radionuclide imaging/scanning><radionuclide scanning><recruit><response><sex><sleep diseases><sleep disruption><sleep dysfunction><sleep dysregulation><sleep illness><sleep measurement><sleep polysomnography><sleep problem><sleep quality><sleep/wake disruption><sleep/wake disturbance><stem><synaptic circuit><synaptic circuitry><trial regimen><trial treatment><α synuclein gene><α-syn><α-synuclein>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Aleksandar Videnovic

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$600,926
FY 2025

Project Title

A Consortium for Gut-Brain Communication in Parkinson's Disease

Grant Number:

5U01DK140933-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract We plan to initiate participation in the NIH U01 Consortium for Gut-Brain Communication in Parkinson’s Disease (PD) (GBPDC) including contribution of PD patients across the spectrum of disease, with and without GI symptoms and age/sex matched healthy controls into the regist...

Research Terms

<Affect><Age><Alimentary Canal><Amaze><Brain><Brain Nervous System><Brain Stem><Brainstem><CNS Nervous System><Caring><Cell Communication and Signaling><Cell Signaling><Central Nervous System><Characteristics><Circadian Dysregulation><Circadian Rhythms><Clinical><Clinical Research><Clinical Study><Clinical Treatment><Collection><Colon><DA Neuron><Data><Degenerative Neurologic Disorders><Dependence><Deterioration><Digestive Tract><Disease><Disorder><Dopamine neuron><Drugs><Dysfunction><Dyskinesia Syndromes><Emesis><Encephalon><Enteral><Enteric><Functional MRI><Functional Magnetic Resonance Imaging><Functional disorder><GI Tract><Gamma Camera Imaging><Gastric Stasis><Gastrointestinal Diseases><Gastrointestinal Tract><Gastrointestinal tract structure><Gastroparesis><General Hospitals><Goals><Health><Hour><Human><Image><Inpatients><Intracellular Communication and Signaling><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Massachusetts><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Melatonin><Modern Man><Motility><Movement Disorder Syndromes><Movement Disorders><NAC precursor><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Nausea><Nerve><Nervous System><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neuraxis><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Body System><Neurologic Degenerative Conditions><Neurologic Organ System><Nuclear Magnetic Resonance Imaging><Nyctohemeral Rhythm><Outcome><PARK1 protein><PARK4 protein><Paralysis Agitans><Parkinson><Parkinson Disease><Participant><Pathologic><Pathologic Processes><Pathological Processes><Patient Recruitments><Patient Selection><Patient Self-Report><Patients><Pattern><Peripheral><Pharmaceutical Preparations><Phenotype><Physiology><Physiopathology><Polysomnography><Population><Primary Parkinsonism><QOL><Quality of life><Questionnaires><Radioisotope Scanning><Radionuclide Imaging><Registries><Reporting><Research><SNCA><SNCA protein><Scintigraphy><Self-Report><Signal Transduction><Signal Transduction Systems><Signaling><Site><Sleep><Sleep Disorders><Sleep Monitoring><Sleep disturbances><Somnography><Stomach><Substantia Nigra><Substantia nigra structure><Symptoms><System><Testing><Thick><Thickness><Twenty-Four Hour Rhythm><United States National Institutes of Health><Vomiting><Zeugmatography><a-syn><a-synuclein><aberrant sleep><absorption><actigraph><actigraphy><ages><alimentary tract><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><biological signal transduction><circadian><circadian abnormality><circadian disruption><circadian disturbance><circadian dysfunction><circadian impairment><circadian process><circadian rhythmicity><clinical intervention><clinical therapy><cohort><daily biorhythm><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><delayed gastric emptying><digestive canal><disease control><disorder control><disrupted sleep><disturbed sleep><dopaminergic neuron><drug/agent><dysmotility><dysmotility syndrome><experience><fMRI><gastric><gastrointestinal disorder><gastrointestinal function><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><imaging><impaired sleep><innovate><innovation><innovative><irregular sleep><microbiome><motility disorder><motor deficit><neural circuit><neural circuitry><neurocircuitry><neurodegenerative illness><non A-beta component of AD amyloid><non A4 component of amyloid precursor><participant recruitment><pathophysiology><patient population><poor sleep><potential biological marker><potential biomarker><quality of sleep><radionuclide imaging/scanning><radionuclide scanning><recruit><response><sex><sleep diseases><sleep disruption><sleep dysfunction><sleep dysregulation><sleep illness><sleep measurement><sleep polysomnography><sleep problem><sleep quality><sleep/wake disruption><sleep/wake disturbance><stem><synaptic circuit><synaptic circuitry><trial regimen><trial treatment><α synuclein gene><α-syn><α-synuclein>
View Full Project Details on NIH Reporter
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RUSTEM F ISMAGILOV

CALIFORNIA INSTITUTE OF TECHNOLOGY, PASADENA, CA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$594,934
FY 2025

Project Title

Viral MEM: Viral Enrichment and Precise Stochastic Quantification with Microbial Context Preservation for Rigorous Virome Analysis of Challenging Human Samples

Grant Number:

5U01DE034199-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/20/2024

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Overview. This U01 proposal is dedicated to advancing the Human Virome Project (HVP) by addressing several key objectives outlined in RFA-RM-23-018 NOFO. The project's focus is on the development and validation of innovative technologies that enhance rigor and reproducibility of viro...

Research Terms

<Abscission><Address><Alimentary Canal><Bacteria><Bacteriophages><Biological><Biomass><Biopsy><Celiac Disease><Celiac Sprue><Cell Communication and Signaling><Cell Signaling><Coeliac Disease><Colon><DNA><Data><Dedications><Deoxyribonucleic Acid><Detection><Development><Digestive Tract><Disease><Disorder><Enhancement Technology><Excision><Extirpation><GI Tract><Gastrointestinal Tract><Gastrointestinal tract structure><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><Health><Human><Human Microbiome><Immune><Immune system><Immunes><Intestinal><Intestines><Intracellular Communication and Signaling><Location><Lower GI Tract><Lower Gastrointestinal Tract><Measurement><Methods><Microbe><Microbiomics><Modern Man><Noise><Non-tropical Sprue><Nontropical Sprue><Nucleic Acids><Oral><Outcome><Performance><Phages><Play><Process><R-Series Research Projects><R01 Mechanism><R01 Program><Rectum><Removal><Reproducibility><Research><Research Grants><Research Project Grants><Research Projects><Rest><Role><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Small Intestines><Structure><Surgical Removal><Swab><Techniques><Technology><Tissue Sample><Vagina><Validation><Viral><Viral Burden><Viral Load><Viral Load result><Virus><Work><alimentary tract><bacterial virus><biologic><biological signal transduction><bowel><cohort><cost effective><cost effectiveness><data integration><data quality><design><designing><detection limit><developmental><digestive canal><fungus><host microbe association><host microbe relationship><host-microbe interactions><host-microbial interactions><host-microorganism interactions><human tissue><human virome><human-associated microbiome><idiopathic steatorrhea><ileum><improved><innovate><innovation><innovative><innovative technologies><insight><microbial><microbiome><microbiome research><microbiome science><microbiome studies><new diagnostics><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><next generation diagnostics><novel><novel diagnostics><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><novel virus><particle><preservation><resection><saliva sample><salivary sample><simulation><small bowel><social role><technology implementation><technology validation><tool><validations><viral microbiome><virome>
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Chang-Lung Lee

DUKE UNIVERSITY, DURHAM, NC

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$565,250
FY 2025

Project Title

Serum pro-N-cadherin as an early biomarker of radiation-induced heart disease

Grant Number:

1U01AI189426-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/6/2025

End Date:

7/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

In the scenario of a nuclear accident or radiological attack, the survivors of acute radiation syndrome (ARS) may be at risk of developing Delayed Effects of Acute Radiation Exposure (DEARE), which can lead to severe morbidity and death due to injury of multiple organs such as the heart. Although it...

Research Terms

<A-bomb><Acute><Acute Radiation Syndrome><Affect><Alimentary Canal><Animal Model><Animal Models and Related Studies><Applications Grants><Autopsy><Biological Markers><Blood Sample><Blood Serum><Blood specimen><Body Tissues><Breast Cancer><Breast Cancer therapy><Cancer Patient><Cancer Treatment><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Transplantation><Cardiovascular Diseases><Cause of Death><Cell Body><Cell surface><Cells><Cessation of life><Chest><Circulation><Data><Death><Development><Diagnosis><Digestive Tract><Dimerization><Dose><ELISA><Electromagnetic Energy><Electromagnetic Radiation><Electromagnetic Waves><Enzyme-Linked Immunosorbent Assay><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Esophageal Cancer><Esophagus Cancer><Exposure to><FDA approved><Fibroblasts><Fibrosis><Fibrosis in the heart><Fibrosis in the myocardium><Fibrosis within the heart><Fibrosis within the myocardium><Fibrotic myocardium><GI Tract><Gastrointestinal Tract><Gastrointestinal tract structure><General Population><General Public><Goals><Golgi><Golgi Apparatus><Golgi Complex><Graft Rejection><Grant Proposals><Heart><Heart Diseases><Heart Grafting><Heart Injuries><Heart Transplantation><Heart failure><Hematologic Body System><Hematologic Organ System><Hematopoietic Body System><Hematopoietic System><Human><In Vitro><Individual><Intestinal><Intestines><Ionizing Electromagnetic Radiation><Ionizing radiation><Japan><Kidney><Kidney Urinary System><Legal patent><Long-Term Survivors><Lung><Lung Respiratory System><Malignant Breast Neoplasm><Malignant Esophageal Neoplasm><Malignant Esophageal Tumor><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Tumor of the Esophagus><Malignant Tumor of the Lung><Malignant neoplasm of esophagus><Malignant neoplasm of lung><Mice><Mice Mammals><Modern Man><Morbidity><Morbidity - disease rate><Multiple Injuries><Multiple Trauma><Murine><Mus><Myocardial depression><Myocardial dysfunction><N-Cadherin><Nuclear><Nuclear Accidents><Nuclear Radiology><Organ><Patents><Pathogenesis><Pathologic><Patients><Population><Predicting Risk><Protein Dimerization><Proteins><Publications><Publishing><Pulmonary Cancer><Pulmonary malignant Neoplasm><Radiation><Radiation Accidents><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation Toxicity><Radiation exposure><Radiation induced damage><Radiation therapy><Radiation-Ionizing Total><Radiotherapeutics><Radiotherapy><Radiotoxicity><Reporting><Risk><Sampling><Scientific Publication><Serology><Serum><Survivors><Symptoms><Technology><Terrorism><Testing><Therapeutic Intervention><Thorace><Thoracic><Thorax><Time><Tissues><Total Radiation><Transplant Rejection><Transplantation Rejection><alimentary tract><animal rule><anti-cancer therapy><atom bomb><atomic bomb><bio-markers><biologic marker><biomarker><bowel><cancer therapy><cancer-directed therapy><cardiac disease risk><cardiac disorder risk><cardiac dysfunction><cardiac failure><cardiac fibrosis><cardiac graft><cardiac injury><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular injury><cohort><coronary fibrosis><cross reactivity><developmental><digestive canal><early biomarkers><early detection biomarkers><early detection markers><enzyme linked immunoassay><epidemiologic investigation><epidemiology study><experiment><experimental research><experimental study><experiments><fibrotic heart><forecasting risk><heart disease risk><heart disorder><heart disorder risk><heart dysfunction><heart fibrosis><heart transplant><high risk><in vivo><intervention therapy><ionizing output><irradiation><irradiation injury><irradiation response><lung cancer><malignant breast tumor><model of animal><myocardial fibrosis><necropsy><non-human primate><nonhuman primate><nuclear disaster><nuclear event><nuclear incident><oesophageal cancer><pig model><piglet model><polytrauma><porcine model><postmortem><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><prevent><preventing><radiation attack><radiation damage><radiation disaster><radiation event><radiation incident><radiation poisoning><radiation response><radiation treatment><radiological accident><radiological attack><radiological disaster><radiological event><radiological incident><renal><response to radiation><risk prediction><risk predictions><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><swine model><terrorist attack><treatment with radiation>
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Manisha Palta

DUKE UNIVERSITY, DURHAM, NC

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$565,250
FY 2025

Project Title

Serum pro-N-cadherin as an early biomarker of radiation-induced heart disease

Grant Number:

1U01AI189426-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/6/2025

End Date:

7/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

In the scenario of a nuclear accident or radiological attack, the survivors of acute radiation syndrome (ARS) may be at risk of developing Delayed Effects of Acute Radiation Exposure (DEARE), which can lead to severe morbidity and death due to injury of multiple organs such as the heart. Although it...

Research Terms

<A-bomb><Acute><Acute Radiation Syndrome><Affect><Alimentary Canal><Animal Model><Animal Models and Related Studies><Applications Grants><Autopsy><Biological Markers><Blood Sample><Blood Serum><Blood specimen><Body Tissues><Breast Cancer><Breast Cancer therapy><Cancer Patient><Cancer Treatment><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Transplantation><Cardiovascular Diseases><Cause of Death><Cell Body><Cell surface><Cells><Cessation of life><Chest><Circulation><Data><Death><Development><Diagnosis><Digestive Tract><Dimerization><Dose><ELISA><Electromagnetic Energy><Electromagnetic Radiation><Electromagnetic Waves><Enzyme-Linked Immunosorbent Assay><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Esophageal Cancer><Esophagus Cancer><Exposure to><FDA approved><Fibroblasts><Fibrosis><Fibrosis in the heart><Fibrosis in the myocardium><Fibrosis within the heart><Fibrosis within the myocardium><Fibrotic myocardium><GI Tract><Gastrointestinal Tract><Gastrointestinal tract structure><General Population><General Public><Goals><Golgi><Golgi Apparatus><Golgi Complex><Graft Rejection><Grant Proposals><Heart><Heart Diseases><Heart Grafting><Heart Injuries><Heart Transplantation><Heart failure><Hematologic Body System><Hematologic Organ System><Hematopoietic Body System><Hematopoietic System><Human><In Vitro><Individual><Intestinal><Intestines><Ionizing Electromagnetic Radiation><Ionizing radiation><Japan><Kidney><Kidney Urinary System><Legal patent><Long-Term Survivors><Lung><Lung Respiratory System><Malignant Breast Neoplasm><Malignant Esophageal Neoplasm><Malignant Esophageal Tumor><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Tumor of the Esophagus><Malignant Tumor of the Lung><Malignant neoplasm of esophagus><Malignant neoplasm of lung><Mice><Mice Mammals><Modern Man><Morbidity><Morbidity - disease rate><Multiple Injuries><Multiple Trauma><Murine><Mus><Myocardial depression><Myocardial dysfunction><N-Cadherin><Nuclear><Nuclear Accidents><Nuclear Radiology><Organ><Patents><Pathogenesis><Pathologic><Patients><Population><Predicting Risk><Protein Dimerization><Proteins><Publications><Publishing><Pulmonary Cancer><Pulmonary malignant Neoplasm><Radiation><Radiation Accidents><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation Toxicity><Radiation exposure><Radiation induced damage><Radiation therapy><Radiation-Ionizing Total><Radiotherapeutics><Radiotherapy><Radiotoxicity><Reporting><Risk><Sampling><Scientific Publication><Serology><Serum><Survivors><Symptoms><Technology><Terrorism><Testing><Therapeutic Intervention><Thorace><Thoracic><Thorax><Time><Tissues><Total Radiation><Transplant Rejection><Transplantation Rejection><alimentary tract><animal rule><anti-cancer therapy><atom bomb><atomic bomb><bio-markers><biologic marker><biomarker><bowel><cancer therapy><cancer-directed therapy><cardiac disease risk><cardiac disorder risk><cardiac dysfunction><cardiac failure><cardiac fibrosis><cardiac graft><cardiac injury><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular injury><cohort><coronary fibrosis><cross reactivity><developmental><digestive canal><early biomarkers><early detection biomarkers><early detection markers><enzyme linked immunoassay><epidemiologic investigation><epidemiology study><experiment><experimental research><experimental study><experiments><fibrotic heart><forecasting risk><heart disease risk><heart disorder><heart disorder risk><heart dysfunction><heart fibrosis><heart transplant><high risk><in vivo><intervention therapy><ionizing output><irradiation><irradiation injury><irradiation response><lung cancer><malignant breast tumor><model of animal><myocardial fibrosis><necropsy><non-human primate><nonhuman primate><nuclear disaster><nuclear event><nuclear incident><oesophageal cancer><pig model><piglet model><polytrauma><porcine model><postmortem><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><prevent><preventing><radiation attack><radiation damage><radiation disaster><radiation event><radiation incident><radiation poisoning><radiation response><radiation treatment><radiological accident><radiological attack><radiological disaster><radiological event><radiological incident><renal><response to radiation><risk prediction><risk predictions><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><swine model><terrorist attack><treatment with radiation>
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Elizabeth Miller

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$548,244
FY 2025

Project Title

CE22-013 A community-centered collective efficacy intervention for prevention of community violence

Grant Number:

5U01CE003524-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

ALLCDC

Start Date:

9/30/2022

End Date:

9/29/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Violence impacts the life trajectories of far too many adolescents, with the highest incidence of violence exposure concentrated among youth in urban settings. In response to RFA-CE-22-013, Rigorous Evaluation of Commu- nity-Centered Approaches for the Prevention of Community Violence (U01), this st...

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Zhaozhong Zhu

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 60/100
Likely hiring
Large award
Active award
$3,181,155
FY 2025

Project Title

Residential Greenness, Airway Microbiome,and Incident Childhood Asthma

Grant Number:

1R01ES036966-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/18/2025

End Date:

9/17/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The major challenges for developing primary prevention strategies for childhood asthma are the early identification of modifiable risk factors (e.g., environmental factors, microbiome) and the heterogeneity of asthma. Our group has applied integrated omics approaches to infancy data, and identified ...

Research Terms

<0-11 years old><21+ years old><6 year old><6 years of age><7 year old><7 years of age><Active Follow-up><Activities of Daily Living><Activities of everyday life><Adult><Adult Human><Affect><Age><Air Pollution><Allergic asthma><Asthma><Asthma in Children><B catarrhalis><B. catarrhalis><Birth><Blood Eosinophil><Branhamella catarrhalis><Bronchial Asthma><Bronchial-Dilating Agents><Bronchiolitis><Bronchodilator Agents><Bronchodilators><CCL7><CCL7 gene><Causality><Child><Child Youth><Childhood Asthma><Children (0-21)><Chlorophyll><Clinical><Cohort Studies><Collaborations><Complex><Concurrent Studies><D pneumoniae><D. pneumoniae><DNA><Data><Data Set><Deoxyribonucleic Acid><Development><Diplococcus pneumoniae><Disease><Disorder><Early identification><Enrollment><Environment><Environmental Factor><Environmental Health><Environmental Health Science><Environmental Risk Factor><Eosinophilic Granulocyte><Eosinophilic Leukocyte><Epidemiology><Etiology><Exposure to><Extrinsic asthma><Fatty Acid Metabolism Pathway><Finland><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Susceptibility><Genetic propensity><Genome><Glycolysis><Heterogeneity><Hospital Admission><Hospitalization><Immune response><Immune system><Immunity><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Infant><Inherited Predisposition><Inherited Susceptibility><Interview><Investigators><Knowledge><Lead><Learning><Life><Link><M catarrhalis><M. catarrhalis><MARC><MCP-3><MCP3><Machine Learning><Marrow Eosinophil><Measurement><Measures><Mediation><Medical Records><Modeling><Moraxella catarrhalis><NC28><NIEHS><National Institute of Environmental Health Sciences><Negotiating><Negotiation><Parents><Participant><Parturition><Pb element><Pediatric asthma><Persons><Phenotype><Pneumococcus><Pneumonia><Population><Position><Positioning Attribute><Prevalence><Preventative strategy><Prevention strategy><Preventive strategy><Primary Prevention><Prospective cohort><Public Health><Reproducibility><Research><Research Personnel><Researchers><Risk><Risk Factors><Risk Reduction><Role><S pneumoniae><S. pneumoniae><SCYA7><Sampling><Shapes><Strategic Planning><Streptococcus pneumoniae><Systems Biology><Techniques><Testing><Work><active followup><adulthood><age 6 years><age 7 years><ages><airway microbiome><alter microbiome><asthma prevention><atopic asthma><causation><cohort><community microbes><daily living function><daily living functionality><developmental><disease causation><enroll><environmental risk><eosinophil><epidemiologic><epidemiological><extrinsic allergic asthma><fatty acid metabolism><follow up><follow-up><followed up><followup><functional ability><functional capacity><genetic approach><genetic etiology><genetic mechanism of disease><genetic strategy><genetic vulnerability><genetically predisposed><global gene expression><global transcription profile><heavy metal Pb><heavy metal lead><high risk><high risk group><high risk individual><high risk people><high risk population><host response><immune system response><immunoresponse><indexing><infancy><infantile><innovate><innovation><innovative><kids><lumen dilator><machine based learning><malleable risk><metabolome><metabonome><metagenome><metagenome sequencing><metagenomic sequencing><methylome><microbe community><microbial community><microbiome><microbiome adaptation><microbiome alteration><microbiome community composition><microbiome composition><microbiome perturbation><microbiome species composition><microbiome structure><microorganism community><modifiable risk><multiomics><multiple omics><novel><panomics><parent><polygenetic risk scores><polygenic risk score><polymicrobial community><prevent><preventing><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><respiratory infection virus><respiratory microbiome><respiratory tract microbiome><risk-reducing><seven year old><seven years of age><six year old><six years of age><social role><transcriptome><treatment strategy><youngster>
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JENNY C-N CHANG

METHODIST HOSPITAL RESEARCH INSTITUTE, HOUSTON, TX

Good lead · 60/100
Likely hiring
Solid budget
Active award
Team-scale grant
$367,053
FY 2026

Project Title

A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)

Grant Number:

5U01CA268813-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/10/2022

End Date:

12/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Metaplastic breast cancer (MpBC) is a rare subset accounting for <1% of all breast cancers. However, MpBC is a significant health challenge as it exhibits the most dismal prognosis of all breast cancers, even worse than triple-negative breast cancer (TNBC), with a survival rate of 8 months ...

Research Terms

<3-Phosphoinositide Dependent Protein Kinase-1><AKT><Accounting><Acetates><Akt protein><Anzatax><Apoptosis><Apoptosis Pathway><Arginine><Asotax><Automobile Driving><Blood><Blood Reticuloendothelial System><Body Tissues><Breast Cancer><Breast Cancer Patient><Breast Cancer cell line><Breast PDX models><Breast Tumor Patient><Breast tumor cell line><Bristaxol><Cancer Center><Cancers><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell to Cell Communication and Signaling><Cell-Cell Signaling><Cell-to-Cell Interaction><Cells><Cellular Expansion><Cellular Growth><Chemoresistance><Clinical Trials><Core Biopsy><Core Needle Biopsy><Cytotoxic agent><Cytotoxic drug><D-NMMA><DNA mutation><Data Analyses><Data Analysis><Development><Dioscorea><Disease><Disorder><Dose><Drug resistance><Drugs><EDRF Synthase><EGF Receptor><EGFR><ERBB Protein><Ecologic Systems><Ecological Systems><Ecosystem><Endocrine><Endocrine Therapy><Endogenous Nitrate Vasodilator><Endothelium-Derived Growth Factor Synthase><Endothelium-Derived Nitric Oxide><Enrollment><Environment><Epidermal Growth Factor Receptor><Epidermal Growth Factor Receptor Kinase><Epidermal Growth Factor Receptor Protein-Tyrosine Kinase><Epidermal Growth Factor-Urogastrone Receptors><Epithelium><Estrogen Receptors><Exhibits><Faslodex><Fulvestrant><Generalized Growth><Genetic Change><Genetic defect><Genetic mutation><Genus Dioscorea><Growth><Guanylyl Cyclase-Activating Factor Synthase><HER1><HR positive><Health><Hormonal Therapy><Human><ICI 182,780><ICI 182780><INOS><Immunofluorescence><Immunofluorescence Immunologic><Inducible Nitric Oxide Synthase><Inositide Phospholipids><Inositol Phosphoglycerides><Inositol Phospholipids><Intracellular Communication and Signaling><Investigation><Kinases><L-Arginine><L-Monomethylarginine><L-NMMA><Lead><Ligands><Lymphoid Cell><MDACC><MMAC1><MMAC1 protein><Macrophage Nitric Oxide Synthase><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mediating><Medication><Mesenchymal><Metaplastic breast cancer><Metaplastic carcinoma of the breast><Metastasis to the Lung><Metastatic Neoplasm to the Lung><Metastatic Tumor to the Lung><Methodist Church><Methodists><Modeling><Modern Man><Molecular><Mononitrogen Monoxide><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><Mutate><Mutated in Multiple Advanced Cancers 1><Mutation><Myeloid Cells><N(G)-Methylarginine><N(G)-Monomethyl-D-Arginine><N(G)-Monomethylarginine><N(omega)-Monomethyl-L-Arginine><N-Methylarginine><NCI Organization><NG-Monomethyl-L-Arginine><NIH><NO Synthase><NOS2><NOS2A><NOS2A gene><NOS2A, Inducible, Hepatocyte><National Cancer Institute><National Institutes of Health><Nature><Nitric Oxide><Nitric Oxide Synthase><Nitric Oxide Synthase 2A><Nitric Oxide Synthetase Inhibitor><Nitric-Oxide Synthetase><Nitrogen Monoxide><Nitrogen Protoxide><Oncogenesis><Oncogenic><Outcome><PHTS gene><PHTS protein><PI3K-Alpha><PIK3-Alpha><PIK3CA><PIK3CA gene><PIQRAY><PKB Kinase><PTEN><PTEN gene><PTEN protein><PTEN1><Paclitaxel><Paclitaxel (Taxol)><Pathway interactions><Patient-derived xenograft models of breast cancer><Patients><Pattern><Pb element><Pharmaceutical Preparations><Phase><Phase 2 Clinical Trials><Phase II Clinical Trials><Phosphatase and Tensin Homolog><Phosphatase and Tensin Homolog Deleted on Chromosome 10><Phosphatidyl Inositol><Phosphatidylinositol 3-Kinase, Catalytic, 110-kD, Alpha><Phosphatidylinositol 3-Kinase, Catalytic, Alpha><Phosphatidylinositols><Phosphoinositides><Phosphotransferase Gene><Phosphotransferases><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Praxel><Preclinical data><Process><Production><Progesterone Receptors><Progestin Receptors><Prognosis><Programmed Cell Death><Progression-Free Survivals><Protein Kinase B><Proto-Oncogene Proteins c-akt><PtdIns><Publishing><RAC-PK protein><Radiation therapy><Radiotherapeutics><Radiotherapy><Receptor Protein><Refractory><Regimen><Research><Research Resources><Research Specimen><Resistance><Resources><Ribosomal Proteins><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Specimen><Stem Cell like><Stromal Cells><Survival Rate><System><TGF-alpha Receptor><TNBC><TUNEL Assay><Taxol><Taxol A><Taxol Konzentrat><TdT-Mediated dUTP Nick End Labeling Assay><Testing><Therapeutic><Therapeutic Hormone><Tissue Growth><Tissues><Transforming Growth Factor alpha Receptor><Translating><Transphosphorylases><Treatment Efficacy><Treatment Protocols><Treatment Regimen><Treatment Schedule><Tumor Cell><United States National Institutes of Health><University of Texas M D Anderson Cancer Center><University of Texas MD Anderson Cancer Center><Urogastrone Receptor><Yam><Yam - dietary><after menopause><alpelisib><biological signal transduction><biomarker identification><breast cancer PDX><breast cancer patient-derived xenograft><c-akt protein><c-erbB-1><c-erbB-1 Protein><cancer microenvironment><cancer progenitor><cancer progenitor cells><cancer stem cell><cancer stem like cell><cancers that are rare><cell growth><chemoresistant><chemotherapy><chemotherapy resistance><chemotherapy resistant><clinical center><combinatorial><data interpretation><determine efficacy><develop drug resistance><developmental><driving><drug resistance development><drug resistant><drug/agent><druggable target><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><endocrine treatment><endothelial cell derived relaxing factor><enroll><erbB-1><erbB-1 Proto-Oncogene Protein><erbBl><estrogen receptor protein><estrophile><estrophilin><evaluate efficacy><examine efficacy><following menopause><gain of function><genome mutation><hPDK1><heavy metal Pb><heavy metal lead><hormonal treatment><hormone receptor +><hormone receptor-positive><hormone therapy><hormone treatment><identification of biomarkers><identification of new biomarkers><imaging system><individuals with breast cancer><inhibitor><intercellular communication><intervention efficacy><lung metastasis><malignancy><malignant breast tumor><malignant progenitor><malignant stem cell><marker identification><metastasize to the lung><multi-modal data><multi-modal datasets><multimodal data><multimodal datasets><mutated in multiple advanced cancers 1 protein><neoplasm/cancer><neoplastic cell><nitric oxide synthase inhibitor><objective response rate><omega-N-Methylarginine><oncogenic progenitor><oncogenic stem cells><ontogeny><p110-Alpha><past menopause><pathway><patients with breast cancer><person with breast cancer><phase 2 study><phase II protocol><phase II study><phosphatase and tensin homologue on chromosome ten><post-menopausal><postmenopausal><postmenopausal status><preclinical findings><preclinical information><progenitor capacity><progenitor cell like><progenitor cell maintenance><progenitor cell pool><progenitor cell population><progenitor cell regeneration><progenitor cell self renewal><progenitor like cancer cell><progenitor maintenance><progenitor pool><progenitor population><progenitor regeneration><progenitor self renewal><progenitor-like><protein kinase B kinase><proto-oncogene protein RAC><proto-oncogene protein akt><proto-oncogene protein c-erbB-1><pulmonary metastasis><rac protein kinase><radiation treatment><rare cancer><rare malignancy><rare tumor><receptor><related to A and C-protein><resistance to Drug><resistance to therapy><resistant><resistant to Drug><resistant to therapy><response><response to therapy><response to treatment><secondary outcome><small molecule><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stem and progenitor cell population><stem and progenitor cell regeneration><stem and progenitor cell self renewal><stem cell characteristics><stem cell maintenance><stem cell pool><stem cell population><stem cell regeneration><stem cell self renewal><stem like cancer cell><stem-like><stemness><taxane><therapeutic efficacy><therapeutic resistance><therapeutic response><therapeutically effective><therapy efficacy><therapy resistant><therapy response><treatment resistance><treatment response><treatment responsiveness><treatment with radiation><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor growth><tumor microenvironment><tumorigenesis>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

FUNDA MERIC-BERNSTAM

METHODIST HOSPITAL RESEARCH INSTITUTE, HOUSTON, TX

Good lead · 60/100
Likely hiring
Solid budget
Active award
Team-scale grant
$367,053
FY 2026

Project Title

A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)

Grant Number:

5U01CA268813-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/10/2022

End Date:

12/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Metaplastic breast cancer (MpBC) is a rare subset accounting for <1% of all breast cancers. However, MpBC is a significant health challenge as it exhibits the most dismal prognosis of all breast cancers, even worse than triple-negative breast cancer (TNBC), with a survival rate of 8 months ...

Research Terms

<3-Phosphoinositide Dependent Protein Kinase-1><AKT><Accounting><Acetates><Akt protein><Anzatax><Apoptosis><Apoptosis Pathway><Arginine><Asotax><Automobile Driving><Blood><Blood Reticuloendothelial System><Body Tissues><Breast Cancer><Breast Cancer Patient><Breast Cancer cell line><Breast PDX models><Breast Tumor Patient><Breast tumor cell line><Bristaxol><Cancer Center><Cancers><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell to Cell Communication and Signaling><Cell-Cell Signaling><Cell-to-Cell Interaction><Cells><Cellular Expansion><Cellular Growth><Chemoresistance><Clinical Trials><Core Biopsy><Core Needle Biopsy><Cytotoxic agent><Cytotoxic drug><D-NMMA><DNA mutation><Data Analyses><Data Analysis><Development><Dioscorea><Disease><Disorder><Dose><Drug resistance><Drugs><EDRF Synthase><EGF Receptor><EGFR><ERBB Protein><Ecologic Systems><Ecological Systems><Ecosystem><Endocrine><Endocrine Therapy><Endogenous Nitrate Vasodilator><Endothelium-Derived Growth Factor Synthase><Endothelium-Derived Nitric Oxide><Enrollment><Environment><Epidermal Growth Factor Receptor><Epidermal Growth Factor Receptor Kinase><Epidermal Growth Factor Receptor Protein-Tyrosine Kinase><Epidermal Growth Factor-Urogastrone Receptors><Epithelium><Estrogen Receptors><Exhibits><Faslodex><Fulvestrant><Generalized Growth><Genetic Change><Genetic defect><Genetic mutation><Genus Dioscorea><Growth><Guanylyl Cyclase-Activating Factor Synthase><HER1><HR positive><Health><Hormonal Therapy><Human><ICI 182,780><ICI 182780><INOS><Immunofluorescence><Immunofluorescence Immunologic><Inducible Nitric Oxide Synthase><Inositide Phospholipids><Inositol Phosphoglycerides><Inositol Phospholipids><Intracellular Communication and Signaling><Investigation><Kinases><L-Arginine><L-Monomethylarginine><L-NMMA><Lead><Ligands><Lymphoid Cell><MDACC><MMAC1><MMAC1 protein><Macrophage Nitric Oxide Synthase><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mediating><Medication><Mesenchymal><Metaplastic breast cancer><Metaplastic carcinoma of the breast><Metastasis to the Lung><Metastatic Neoplasm to the Lung><Metastatic Tumor to the Lung><Methodist Church><Methodists><Modeling><Modern Man><Molecular><Mononitrogen Monoxide><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><Mutate><Mutated in Multiple Advanced Cancers 1><Mutation><Myeloid Cells><N(G)-Methylarginine><N(G)-Monomethyl-D-Arginine><N(G)-Monomethylarginine><N(omega)-Monomethyl-L-Arginine><N-Methylarginine><NCI Organization><NG-Monomethyl-L-Arginine><NIH><NO Synthase><NOS2><NOS2A><NOS2A gene><NOS2A, Inducible, Hepatocyte><National Cancer Institute><National Institutes of Health><Nature><Nitric Oxide><Nitric Oxide Synthase><Nitric Oxide Synthase 2A><Nitric Oxide Synthetase Inhibitor><Nitric-Oxide Synthetase><Nitrogen Monoxide><Nitrogen Protoxide><Oncogenesis><Oncogenic><Outcome><PHTS gene><PHTS protein><PI3K-Alpha><PIK3-Alpha><PIK3CA><PIK3CA gene><PIQRAY><PKB Kinase><PTEN><PTEN gene><PTEN protein><PTEN1><Paclitaxel><Paclitaxel (Taxol)><Pathway interactions><Patient-derived xenograft models of breast cancer><Patients><Pattern><Pb element><Pharmaceutical Preparations><Phase><Phase 2 Clinical Trials><Phase II Clinical Trials><Phosphatase and Tensin Homolog><Phosphatase and Tensin Homolog Deleted on Chromosome 10><Phosphatidyl Inositol><Phosphatidylinositol 3-Kinase, Catalytic, 110-kD, Alpha><Phosphatidylinositol 3-Kinase, Catalytic, Alpha><Phosphatidylinositols><Phosphoinositides><Phosphotransferase Gene><Phosphotransferases><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Praxel><Preclinical data><Process><Production><Progesterone Receptors><Progestin Receptors><Prognosis><Programmed Cell Death><Progression-Free Survivals><Protein Kinase B><Proto-Oncogene Proteins c-akt><PtdIns><Publishing><RAC-PK protein><Radiation therapy><Radiotherapeutics><Radiotherapy><Receptor Protein><Refractory><Regimen><Research><Research Resources><Research Specimen><Resistance><Resources><Ribosomal Proteins><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Specimen><Stem Cell like><Stromal Cells><Survival Rate><System><TGF-alpha Receptor><TNBC><TUNEL Assay><Taxol><Taxol A><Taxol Konzentrat><TdT-Mediated dUTP Nick End Labeling Assay><Testing><Therapeutic><Therapeutic Hormone><Tissue Growth><Tissues><Transforming Growth Factor alpha Receptor><Translating><Transphosphorylases><Treatment Efficacy><Treatment Protocols><Treatment Regimen><Treatment Schedule><Tumor Cell><United States National Institutes of Health><University of Texas M D Anderson Cancer Center><University of Texas MD Anderson Cancer Center><Urogastrone Receptor><Yam><Yam - dietary><after menopause><alpelisib><biological signal transduction><biomarker identification><breast cancer PDX><breast cancer patient-derived xenograft><c-akt protein><c-erbB-1><c-erbB-1 Protein><cancer microenvironment><cancer progenitor><cancer progenitor cells><cancer stem cell><cancer stem like cell><cancers that are rare><cell growth><chemoresistant><chemotherapy><chemotherapy resistance><chemotherapy resistant><clinical center><combinatorial><data interpretation><determine efficacy><develop drug resistance><developmental><driving><drug resistance development><drug resistant><drug/agent><druggable target><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><endocrine treatment><endothelial cell derived relaxing factor><enroll><erbB-1><erbB-1 Proto-Oncogene Protein><erbBl><estrogen receptor protein><estrophile><estrophilin><evaluate efficacy><examine efficacy><following menopause><gain of function><genome mutation><hPDK1><heavy metal Pb><heavy metal lead><hormonal treatment><hormone receptor +><hormone receptor-positive><hormone therapy><hormone treatment><identification of biomarkers><identification of new biomarkers><imaging system><individuals with breast cancer><inhibitor><intercellular communication><intervention efficacy><lung metastasis><malignancy><malignant breast tumor><malignant progenitor><malignant stem cell><marker identification><metastasize to the lung><multi-modal data><multi-modal datasets><multimodal data><multimodal datasets><mutated in multiple advanced cancers 1 protein><neoplasm/cancer><neoplastic cell><nitric oxide synthase inhibitor><objective response rate><omega-N-Methylarginine><oncogenic progenitor><oncogenic stem cells><ontogeny><p110-Alpha><past menopause><pathway><patients with breast cancer><person with breast cancer><phase 2 study><phase II protocol><phase II study><phosphatase and tensin homologue on chromosome ten><post-menopausal><postmenopausal><postmenopausal status><preclinical findings><preclinical information><progenitor capacity><progenitor cell like><progenitor cell maintenance><progenitor cell pool><progenitor cell population><progenitor cell regeneration><progenitor cell self renewal><progenitor like cancer cell><progenitor maintenance><progenitor pool><progenitor population><progenitor regeneration><progenitor self renewal><progenitor-like><protein kinase B kinase><proto-oncogene protein RAC><proto-oncogene protein akt><proto-oncogene protein c-erbB-1><pulmonary metastasis><rac protein kinase><radiation treatment><rare cancer><rare malignancy><rare tumor><receptor><related to A and C-protein><resistance to Drug><resistance to therapy><resistant><resistant to Drug><resistant to therapy><response><response to therapy><response to treatment><secondary outcome><small molecule><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stem and progenitor cell population><stem and progenitor cell regeneration><stem and progenitor cell self renewal><stem cell characteristics><stem cell maintenance><stem cell pool><stem cell population><stem cell regeneration><stem cell self renewal><stem like cancer cell><stem-like><stemness><taxane><therapeutic efficacy><therapeutic resistance><therapeutic response><therapeutically effective><therapy efficacy><therapy resistant><therapy response><treatment resistance><treatment response><treatment responsiveness><treatment with radiation><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor growth><tumor microenvironment><tumorigenesis>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

STEPHEN TC WONG

METHODIST HOSPITAL RESEARCH INSTITUTE, HOUSTON, TX

Good lead · 60/100
Likely hiring
Solid budget
Active award
Team-scale grant
$367,053
FY 2026

Project Title

A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)

Grant Number:

5U01CA268813-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/10/2022

End Date:

12/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Metaplastic breast cancer (MpBC) is a rare subset accounting for <1% of all breast cancers. However, MpBC is a significant health challenge as it exhibits the most dismal prognosis of all breast cancers, even worse than triple-negative breast cancer (TNBC), with a survival rate of 8 months ...

Research Terms

<3-Phosphoinositide Dependent Protein Kinase-1><AKT><Accounting><Acetates><Akt protein><Anzatax><Apoptosis><Apoptosis Pathway><Arginine><Asotax><Automobile Driving><Blood><Blood Reticuloendothelial System><Body Tissues><Breast Cancer><Breast Cancer Patient><Breast Cancer cell line><Breast PDX models><Breast Tumor Patient><Breast tumor cell line><Bristaxol><Cancer Center><Cancers><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell to Cell Communication and Signaling><Cell-Cell Signaling><Cell-to-Cell Interaction><Cells><Cellular Expansion><Cellular Growth><Chemoresistance><Clinical Trials><Core Biopsy><Core Needle Biopsy><Cytotoxic agent><Cytotoxic drug><D-NMMA><DNA mutation><Data Analyses><Data Analysis><Development><Dioscorea><Disease><Disorder><Dose><Drug resistance><Drugs><EDRF Synthase><EGF Receptor><EGFR><ERBB Protein><Ecologic Systems><Ecological Systems><Ecosystem><Endocrine><Endocrine Therapy><Endogenous Nitrate Vasodilator><Endothelium-Derived Growth Factor Synthase><Endothelium-Derived Nitric Oxide><Enrollment><Environment><Epidermal Growth Factor Receptor><Epidermal Growth Factor Receptor Kinase><Epidermal Growth Factor Receptor Protein-Tyrosine Kinase><Epidermal Growth Factor-Urogastrone Receptors><Epithelium><Estrogen Receptors><Exhibits><Faslodex><Fulvestrant><Generalized Growth><Genetic Change><Genetic defect><Genetic mutation><Genus Dioscorea><Growth><Guanylyl Cyclase-Activating Factor Synthase><HER1><HR positive><Health><Hormonal Therapy><Human><ICI 182,780><ICI 182780><INOS><Immunofluorescence><Immunofluorescence Immunologic><Inducible Nitric Oxide Synthase><Inositide Phospholipids><Inositol Phosphoglycerides><Inositol Phospholipids><Intracellular Communication and Signaling><Investigation><Kinases><L-Arginine><L-Monomethylarginine><L-NMMA><Lead><Ligands><Lymphoid Cell><MDACC><MMAC1><MMAC1 protein><Macrophage Nitric Oxide Synthase><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mediating><Medication><Mesenchymal><Metaplastic breast cancer><Metaplastic carcinoma of the breast><Metastasis to the Lung><Metastatic Neoplasm to the Lung><Metastatic Tumor to the Lung><Methodist Church><Methodists><Modeling><Modern Man><Molecular><Mononitrogen Monoxide><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><Mutate><Mutated in Multiple Advanced Cancers 1><Mutation><Myeloid Cells><N(G)-Methylarginine><N(G)-Monomethyl-D-Arginine><N(G)-Monomethylarginine><N(omega)-Monomethyl-L-Arginine><N-Methylarginine><NCI Organization><NG-Monomethyl-L-Arginine><NIH><NO Synthase><NOS2><NOS2A><NOS2A gene><NOS2A, Inducible, Hepatocyte><National Cancer Institute><National Institutes of Health><Nature><Nitric Oxide><Nitric Oxide Synthase><Nitric Oxide Synthase 2A><Nitric Oxide Synthetase Inhibitor><Nitric-Oxide Synthetase><Nitrogen Monoxide><Nitrogen Protoxide><Oncogenesis><Oncogenic><Outcome><PHTS gene><PHTS protein><PI3K-Alpha><PIK3-Alpha><PIK3CA><PIK3CA gene><PIQRAY><PKB Kinase><PTEN><PTEN gene><PTEN protein><PTEN1><Paclitaxel><Paclitaxel (Taxol)><Pathway interactions><Patient-derived xenograft models of breast cancer><Patients><Pattern><Pb element><Pharmaceutical Preparations><Phase><Phase 2 Clinical Trials><Phase II Clinical Trials><Phosphatase and Tensin Homolog><Phosphatase and Tensin Homolog Deleted on Chromosome 10><Phosphatidyl Inositol><Phosphatidylinositol 3-Kinase, Catalytic, 110-kD, Alpha><Phosphatidylinositol 3-Kinase, Catalytic, Alpha><Phosphatidylinositols><Phosphoinositides><Phosphotransferase Gene><Phosphotransferases><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Praxel><Preclinical data><Process><Production><Progesterone Receptors><Progestin Receptors><Prognosis><Programmed Cell Death><Progression-Free Survivals><Protein Kinase B><Proto-Oncogene Proteins c-akt><PtdIns><Publishing><RAC-PK protein><Radiation therapy><Radiotherapeutics><Radiotherapy><Receptor Protein><Refractory><Regimen><Research><Research Resources><Research Specimen><Resistance><Resources><Ribosomal Proteins><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Specimen><Stem Cell like><Stromal Cells><Survival Rate><System><TGF-alpha Receptor><TNBC><TUNEL Assay><Taxol><Taxol A><Taxol Konzentrat><TdT-Mediated dUTP Nick End Labeling Assay><Testing><Therapeutic><Therapeutic Hormone><Tissue Growth><Tissues><Transforming Growth Factor alpha Receptor><Translating><Transphosphorylases><Treatment Efficacy><Treatment Protocols><Treatment Regimen><Treatment Schedule><Tumor Cell><United States National Institutes of Health><University of Texas M D Anderson Cancer Center><University of Texas MD Anderson Cancer Center><Urogastrone Receptor><Yam><Yam - dietary><after menopause><alpelisib><biological signal transduction><biomarker identification><breast cancer PDX><breast cancer patient-derived xenograft><c-akt protein><c-erbB-1><c-erbB-1 Protein><cancer microenvironment><cancer progenitor><cancer progenitor cells><cancer stem cell><cancer stem like cell><cancers that are rare><cell growth><chemoresistant><chemotherapy><chemotherapy resistance><chemotherapy resistant><clinical center><combinatorial><data interpretation><determine efficacy><develop drug resistance><developmental><driving><drug resistance development><drug resistant><drug/agent><druggable target><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><endocrine treatment><endothelial cell derived relaxing factor><enroll><erbB-1><erbB-1 Proto-Oncogene Protein><erbBl><estrogen receptor protein><estrophile><estrophilin><evaluate efficacy><examine efficacy><following menopause><gain of function><genome mutation><hPDK1><heavy metal Pb><heavy metal lead><hormonal treatment><hormone receptor +><hormone receptor-positive><hormone therapy><hormone treatment><identification of biomarkers><identification of new biomarkers><imaging system><individuals with breast cancer><inhibitor><intercellular communication><intervention efficacy><lung metastasis><malignancy><malignant breast tumor><malignant progenitor><malignant stem cell><marker identification><metastasize to the lung><multi-modal data><multi-modal datasets><multimodal data><multimodal datasets><mutated in multiple advanced cancers 1 protein><neoplasm/cancer><neoplastic cell><nitric oxide synthase inhibitor><objective response rate><omega-N-Methylarginine><oncogenic progenitor><oncogenic stem cells><ontogeny><p110-Alpha><past menopause><pathway><patients with breast cancer><person with breast cancer><phase 2 study><phase II protocol><phase II study><phosphatase and tensin homologue on chromosome ten><post-menopausal><postmenopausal><postmenopausal status><preclinical findings><preclinical information><progenitor capacity><progenitor cell like><progenitor cell maintenance><progenitor cell pool><progenitor cell population><progenitor cell regeneration><progenitor cell self renewal><progenitor like cancer cell><progenitor maintenance><progenitor pool><progenitor population><progenitor regeneration><progenitor self renewal><progenitor-like><protein kinase B kinase><proto-oncogene protein RAC><proto-oncogene protein akt><proto-oncogene protein c-erbB-1><pulmonary metastasis><rac protein kinase><radiation treatment><rare cancer><rare malignancy><rare tumor><receptor><related to A and C-protein><resistance to Drug><resistance to therapy><resistant><resistant to Drug><resistant to therapy><response><response to therapy><response to treatment><secondary outcome><small molecule><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stem and progenitor cell population><stem and progenitor cell regeneration><stem and progenitor cell self renewal><stem cell characteristics><stem cell maintenance><stem cell pool><stem cell population><stem cell regeneration><stem cell self renewal><stem like cancer cell><stem-like><stemness><taxane><therapeutic efficacy><therapeutic resistance><therapeutic response><therapeutically effective><therapy efficacy><therapy resistant><therapy response><treatment resistance><treatment response><treatment responsiveness><treatment with radiation><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor growth><tumor microenvironment><tumorigenesis>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Regina A. Mangieri

UNIVERSITY OF TEXAS AT AUSTIN, AUSTIN, TX

Good lead · 60/100
Likely hiring
Solid budget
Active award
Team-scale grant
$356,625
FY 2026

Project Title

9/11 Neuroimmunophysiology of excessive alcohol intake

Grant Number:

5U01AA016651-20

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2006

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT This Integrative Neuroscience Initiative on Alcoholism (INIA-Neuroimmune, INIA-N) consortium component is for a U01 research project that seeks to determine how neuroimmune signaling molecules and glia contribute to neuronal adaptations in the nucleus accumbens that promote ...

Research Terms

<Absolute ethanol><Acute><Alcohol Chemical Class><Alcohol Drinking><Alcohol consumption><Alcohol withdrawal syndrome><Alcoholism><Alcohols><Animals><Astrocytes><Astrocytus><Astroglia><Behavior><Behavioral Model><Brain><Brain Nervous System><Brain region><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic><Collaborations><D1 receptor><Development><Dopamine D1 Receptor><ETOH><Electrophysiology><Electrophysiology (science)><Encephalon><EtOH drinking><EtOH use><Ethanol><Ethanol dependence><Ethyl Alcohol><Exhibits><Functional RNA><Funding><GEM model><GEMM model><Genetically Engineered Mouse><Glia><Glial Cells><Glutamates><Goals><Grain Alcohol><Health Hazards><Heavy Drinking><History><Hortega cell><Intake><Interleukins><Intracellular Communication and Signaling><Investigators><Knowledge><Kolliker's reticulum><L-Glutamate><Link><MALAT1><MALAT1 gene><Mediating><Membrane><Methylcarbinol><Mice><Mice Mammals><Microglia><Mission><Molecular><Molecular Analysis><Murine><Mus><NIAAA><National Institute on Alcohol Abuse and Alcoholism><Nerve Cells><Nerve Impulse Transmission><Nerve Transmission><Nerve Unit><Neural Cell><Neurocyte><Neuroglia><Neuroglial Cells><Neuroimmune><Neuronal Transmission><Neurons><Neurophysiology / Electrophysiology><Neurosciences><Non-neuronal cell><Noncoding RNA><Nonneuronal cell><Nontranslated RNA><Nucleus Accumbens><Output><Pathway interactions><Phenotype><Physiology><Play><Productivity><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Receptor Protein><Recording of previous events><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Rewards><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Slice><Structure><Synapses><Synaptic><Testing><Time><Transmission><Untranslated RNA><Work><alcohol effect><alcohol ingestion><alcohol intake><alcohol product use><alcohol response><alcohol use><alcohol withdrawal><alcoholic beverage consumption><alcoholic drink intake><astrocytic glia><axon signaling><axon-glial signaling><axonal signaling><biological signal transduction><brain cell><brain health><cell type><cytokine><developmental><drink heavily><drinking><drinking behavior><electrophysiological><ethanol addiction><ethanol consumption><ethanol dependency><ethanol dependent><ethanol drinking><ethanol effect><ethanol ingestion><ethanol intake><ethanol product use><ethanol response><ethanol use><ethanol withdrawal><excessive alcohol consumption><excessive alcohol ingestion><excessive alcohol intake><excessive drinking><excessive ethanol ingestion><experience><extreme drinking><functional adaptation><genetically engineered mouse model><genetically engineered murine model><gitter cell><glia signaling><glial activation><glial cell activation><glial signaling><glutamatergic><heavy alcohol use><histories><innovate><innovation><innovative><insight><membrane structure><mesoglia><metastasis-associated lung adenocarcinoma transcript 1><microglial cell><microgliocyte><nerve cement><nerve signaling><neural signaling><neuronal><neuronal excitability><neuronal signaling><neurotransmission><noncoding><pathway><perivascular glial cell><receptor><response to alcohol><response to ethanol><social role><synapse><synapse function><synaptic function><transmission process><withdrawal from alcohol>
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Sarah Lyn Karalunas

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Good lead · 58/100
Likely hiring
Large award
Team-scale grant
$3,905,515
FY 2025

Project Title

Person-centered diagnostics and prediction for child dysregulatory psychopathology using novel phenotypes

Grant Number:

5U01MH135970-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2024

End Date:

3/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary This U01 proposal is submitted in response to the NIMH IMPACT RFA (RFA-MH-23-105). It will extend research efforts to both define novel, deployable behavioral phenotypes (highlighting cognitive and emotional transdiagnostic measures) and develop and test diagnostic and prognostic pre...

Research Terms

<0-11 years old><AD/HD><ADHD><Accuracy of Diagnosis><Active Follow-up><Address><Affect><Affective Disorders><Algorithms><Anxiety Disorders><Arousal><Attention><Attention deficit hyperactivity disorder><Behavior><Behavioral><Caring><Child><Child Youth><Childhood><Children (0-21)><Classification><Clinic><Clinical><Clinical Evaluation><Clinical Testing><Cognition><Cognitive><Complex><Computational algorithm><Computer Models><Computerized Medical Record><Computerized Models><Connectionist Models><Country><Data><Data Collection><Data Sources><Deterioration><Diagnosis><Diagnostic><Diagnostic tests><Dimensions><Disruptive Behavior Disorder><ED visit><ER visit><Effectiveness><Electronic Medical Record><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Emotional><Emotions><Evaluation><Face><Goals><Hand><Harvest><Impairment><Laboratories><Learning><Location><Logic><Measures><Mental Health><Mental Hygiene><Methods><Modeling><Mood Disorders><NIMH><National Institute of Mental Health><Negative Valence><Neural Network Models><Neural Network Simulation><Oregon><Outcome><Patient Recruitments><Patients><Perceptrons><Persons><Phenotype><Population><Position><Positioning Attribute><Positive Valence><Predominantly Hyperactive-Impulsive Type Attention-Deficit Disorder><Predominantly Hyperactive-Impulsive Type Hyperactivity Disorder><Preparedness><Problem behavior><Psychiatry><Psychological Health><Psychopathology><Readiness><Records><Recruitment Activity><Reproducibility><Research><Research Resources><Resources><Role><Savings><Site><Symptoms><Systematics><Testing><Time><Underrepresented Groups><Underrepresented Populations><Underserved Population><Work><Youth><Youth 10-21><abnormal psychology><active followup><active recruitment><advanced analytics><aged><alertness><behavior measurement><behavior phenotype><behavioral measure><behavioral measurement><behavioral phenotyping><behavioral problem><clinical care><clinical diagnostics><clinical predictors><clinical prognostic><clinical test><cohort><computational modeling><computational models><computer algorithm><computer based models><computer based prediction><computerized modeling><cost><diagnosis standard><diagnostic ability><diagnostic accuracy><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disruptive behavioral disorder><emotion dysregulation><emotion regulation><emotional dysregulation><emotional regulation><executive control><executive function><faces><facial><follow up><follow-up><followed up><followup><hands><high risk><improved><indexing><informant><innovate><innovation><innovative><kids><machine learning based model><machine learning model><medical diagnostic><new diagnostics><next generation diagnostics><novel><novel diagnostics><outcome prediction><participant recruitment><patient population><pediatric><person centered><prediction algorithm><predictive modeling><prognostic><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><prospective test><research clinical testing><response><service utilization><social role><substance use><substance using><suicidal><suicidality><trait><transfer learning><under representation of groups><under represented groups><under represented people><under represented populations><under served group><under served individual><under served people><under served population><underrepresentation of groups><underrepresented people><underserved group><underserved individual><underserved people><youngster><youth age>
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Bonnie J. Nagel

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Good lead · 58/100
Likely hiring
Large award
Team-scale grant
$3,905,515
FY 2025

Project Title

Person-centered diagnostics and prediction for child dysregulatory psychopathology using novel phenotypes

Grant Number:

5U01MH135970-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2024

End Date:

3/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary This U01 proposal is submitted in response to the NIMH IMPACT RFA (RFA-MH-23-105). It will extend research efforts to both define novel, deployable behavioral phenotypes (highlighting cognitive and emotional transdiagnostic measures) and develop and test diagnostic and prognostic pre...

Research Terms

<0-11 years old><AD/HD><ADHD><Accuracy of Diagnosis><Active Follow-up><Address><Affect><Affective Disorders><Algorithms><Anxiety Disorders><Arousal><Attention><Attention deficit hyperactivity disorder><Behavior><Behavioral><Caring><Child><Child Youth><Childhood><Children (0-21)><Classification><Clinic><Clinical><Clinical Evaluation><Clinical Testing><Cognition><Cognitive><Complex><Computational algorithm><Computer Models><Computerized Medical Record><Computerized Models><Connectionist Models><Country><Data><Data Collection><Data Sources><Deterioration><Diagnosis><Diagnostic><Diagnostic tests><Dimensions><Disruptive Behavior Disorder><ED visit><ER visit><Effectiveness><Electronic Medical Record><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Emotional><Emotions><Evaluation><Face><Goals><Hand><Harvest><Impairment><Laboratories><Learning><Location><Logic><Measures><Mental Health><Mental Hygiene><Methods><Modeling><Mood Disorders><NIMH><National Institute of Mental Health><Negative Valence><Neural Network Models><Neural Network Simulation><Oregon><Outcome><Patient Recruitments><Patients><Perceptrons><Persons><Phenotype><Population><Position><Positioning Attribute><Positive Valence><Predominantly Hyperactive-Impulsive Type Attention-Deficit Disorder><Predominantly Hyperactive-Impulsive Type Hyperactivity Disorder><Preparedness><Problem behavior><Psychiatry><Psychological Health><Psychopathology><Readiness><Records><Recruitment Activity><Reproducibility><Research><Research Resources><Resources><Role><Savings><Site><Symptoms><Systematics><Testing><Time><Underrepresented Groups><Underrepresented Populations><Underserved Population><Work><Youth><Youth 10-21><abnormal psychology><active followup><active recruitment><advanced analytics><aged><alertness><behavior measurement><behavior phenotype><behavioral measure><behavioral measurement><behavioral phenotyping><behavioral problem><clinical care><clinical diagnostics><clinical predictors><clinical prognostic><clinical test><cohort><computational modeling><computational models><computer algorithm><computer based models><computer based prediction><computerized modeling><cost><diagnosis standard><diagnostic ability><diagnostic accuracy><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disruptive behavioral disorder><emotion dysregulation><emotion regulation><emotional dysregulation><emotional regulation><executive control><executive function><faces><facial><follow up><follow-up><followed up><followup><hands><high risk><improved><indexing><informant><innovate><innovation><innovative><kids><machine learning based model><machine learning model><medical diagnostic><new diagnostics><next generation diagnostics><novel><novel diagnostics><outcome prediction><participant recruitment><patient population><pediatric><person centered><prediction algorithm><predictive modeling><prognostic><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><prospective test><research clinical testing><response><service utilization><social role><substance use><substance using><suicidal><suicidality><trait><transfer learning><under representation of groups><under represented groups><under represented people><under represented populations><under served group><under served individual><under served people><under served population><underrepresentation of groups><underrepresented people><underserved group><underserved individual><underserved people><youngster><youth age>
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Christopher Ethan Cox

DUKE UNIVERSITY, DURHAM, NC

Good lead · 56/100
Above-average budget
Very recent
Active award
Team-scale grant
$988,827
FY 2026

Project Title

1/2 Self-directed mobile mindfulness to address ICU survivors' psychological distress: the Lift RCT

Grant Number:

1UG3AT013109-01

Activity Code:

UG3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/23/2026

End Date:

3/31/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Cardiorespiratory conditions such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are among the most common causes of mortality and morbidity. They are also notable for high rates of persistent psychological distress symptoms including depres...

Research Terms

<ARDS><Active Follow-up><Acute Respiratory Distress><Acute Respiratory Distress Syndrome><Address><Adherence><Adult ARDS><Adult RDS><Adult Respiratory Distress Syndrome><Affect><Age><Anxiety><Behavioral><Bryophyta><Bryophyte><COVID associated pneumonia><COVID induced pneumonia><COVID pneumonia><COVID related pneumonia><COVID-19><COVID-19 associated pneumonia><COVID-19 induced pneumonia><COVID-19 pneumonia><COVID-19 related pneumonia><COVID-19 viral pneumonia><CV-19><Cardiac Failure Congestive><Characteristics><Clinical><Clinical Trials><Collaborations><Congestive Heart Failure><Coronavirus Infectious Disease 2019><Da Nang Lung><Data><Demographic Factors><Disease><Disorder><Dose><Education><Education for Intervention><Educational Intervention><Educational aspects><Elements><Emotional Depression><Enrollment><Ensure><Failure><Financial Hardship><Goals><Health><Heart Decompensation><Heterogeneity><History><Hospital Admission><Hospitalization><Hybrids><Instruction Intervention><Intensive Care Units><Intervention><Lead><Lifting><Measures><Mental Depression><Mental Health><Mental Health Services><Mental Hygiene><Mental Hygiene Services><Methods><Mindfulness Approach><Mindfulness Therapy><Mindfulness Training><Mindfulness Treatment><Mindfulness-based Approach><Mindfulness-based Therapy><Mindfulness-based Training><Mindfulness-based Treatment><Morbidity><Mosses><Multi-center trial><Multicenter Trials><Outcome><PTSD><Participant><Patients><Pb element><Persons><Pneumonia><Population><Post-Traumatic Neuroses><Post-Traumatic Stress Disorders><Posttraumatic Neuroses><Preparedness><Psychological Health><QOL><QOL improvement><Quality of life><Questionnaires><RE-AIM><Randomized><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Readiness><Recording of previous events><Research><Research Priority><Role><SARS-CoV-2 associated pneumonia><SARS-CoV-2 induced pneumonia><SARS-CoV-2 pneumonia><SARS-CoV-2 related pneumonia><SARS-CoV-2 viral pneumonia><Sampling><Self Direction><Self Efficacy><Sepsis><Severity of illness><Shock Lung><Site><Social support><Socio-economic status><Socioeconomic Factors><Socioeconomic Status><Spanish/English><Stiff lung><Structure><Subgroup><Survivors><Symptoms><Testing><Training><Training Intervention><Training Programs><Treatment Efficacy><Work><active followup><ages><chronic heart failure><clinical implementation><clinical trial participant><cohort><community engagement><compare to control><comparison control><coronavirus disease 2019><coronavirus disease 2019 associated pneumonia><coronavirus disease 2019 induced pneumonia><coronavirus disease 2019 pneumonia><coronavirus disease 2019 related pneumonia><coronavirus disease associated pneumonia><coronavirus disease induced pneumonia><coronavirus disease pneumonia><coronavirus disease related pneumonia><coronavirus disease-19><coronavirus disease-19 pneumonia><coronavirus infectious disease-19><depression><depression symptom><depressive><depressive symptoms><design><designing><disease severity><economic hardship><economic strain><effectiveness/implementation design><effectiveness/implementation hybrid design><efficacy testing><emotion regulation><emotional regulation><engagement with communities><enroll><enthusiastic atmosphere><enthusiastic environment><experience><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><follow up><follow-up><followed up><followup><future implementation><health and care delivery><health care delivery><health delivery systems><health services delivery><heavy metal Pb><heavy metal lead><histories><implementation framework><implementation intervention><implementation research framework><implementation science framework><improved><improvements in QOL><improvements in quality of life><innovate><innovation><innovative><instructional intervention><intervention design><intervention efficacy><m-Health><mHealth><manage symptom><mental health care><mindfulness><mindfulness intervention><mindfulness-based intervention><mindfulness-based stress reduction><mobile app><mobile application><mobile device application><mobile health><mortality><multiphase optimization strategy><novel><participant interview><physical symptom><pneumonia due to COVID><pneumonia due to COVID-19><pneumonia due to SARS-CoV-2><pneumonia due to coronavirus disease><pneumonia due to coronavirus disease 2019><pneumonia due to severe acute respiratory syndrome coronavirus 2><pneumonia in COVID><pneumonia in COVID-19><pneumonia in SARS-CoV-2><pneumonia in coronavirus disease><pneumonia in coronavirus disease 2019><pneumonia in severe acute respiratory syndrome coronavirus 2><post-trauma stress disorder><posttrauma stress disorder><primary outcome><programs><psychological distress><psychological symptom><quality of life improvement><randomisation><randomization><randomized, clinical trials><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><response><response to therapy><response to treatment><rurality><screening><screenings><severe acute respiratory syndrome coronavirus 2 associated pneumonia><severe acute respiratory syndrome coronavirus 2 induced pneumonia><severe acute respiratory syndrome coronavirus 2 pneumonia><severe acute respiratory syndrome coronavirus 2 related pneumonia><sex><skills><social role><social support network><socio-economic factors><socio-economic position><socioeconomic position><success><supportive atmosphere><supportive environment><symptom management><therapeutic efficacy><therapeutic response><therapy design><therapy efficacy><therapy response><traumatic neurosis><treatment design><treatment effect><treatment response><treatment responsiveness><wet lung>
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EDWARD P RILEY

SAN DIEGO STATE UNIVERSITY, SAN DIEGO, CA

Good lead · 56/100
Above-average budget
Very recent
Active award
Team-scale grant
$515,415
FY 2026

Project Title

Administrative Resource of the CIFASD

Grant Number:

5U24AA014811-23

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/30/2003

End Date:

4/30/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract The Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) is a multidisciplinary, international consortium of research projects and resources charged with improving prevention, diagnosis, and treatment of FASD. The Administrative Core/Resource (AdminC) of CIF...

Research Terms

<21+ years old><3-D><3-Dimensional><3D><Address><Adult><Adult Human><Advisory Committees><Affect><Age><Archives><Area><Behavioral><Biological Markers><Body System><Cardiac><Charge><Clinical><Clinical Research><Clinical Study><Collaborations><Communication><Data><Data Bases><Data Collection><Data Files><Databases><Deposit><Deposition><Diabetes Mellitus><Diagnosis><Diagnostic><Disease><Disorder><Dissemination and Implementation><Dysfunction><Dysmorphology><Education><Educational aspects><Elements><Ensure><Evaluation><FASD><Face><Family><Fetal Alcohol Exposure><Fetal Alcohol Spectrum Disorder><Fetal ETOH Exposure><Fetal Ethanol Exposure><Fetal alcohol effects><Functional disorder><Future><Goals><Health><Hybrids><Hypertension><Immune><Immunes><In Utero Alcohol Exposure><In Utero ETOH Exposure><In Utero Ethanol Exposure><Individual><Inflammatory><Information Dissemination><Infrastructure><Interdisciplinary Research><Interdisciplinary Study><International><Intervention><Intervention Strategies><Investigators><Language><Leadership><MicroRNAs><Mission><Modality><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><NIAAA><National Institute on Alcohol Abuse and Alcoholism><Organ System><Outcome><Pattern><Persons><Physiopathology><Play><Policies><Population><Prenatal Alcohol Exposure><Prenatal ETOH Exposure><Prenatal Ethanol Exposure><Prevalence><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Privatization><Progress Reports><Protocol><Protocols documentation><Provider><Public Health><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resource Allocation><Resources><Risk><Risk Factors><Risk Reduction><Role><Schedule><Science><Scientific Publication><Scientist><Services><Site><Structure><Suggestion><System><Task Forces><Technology><Telemedicine><Testing><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><Work><Writing><accelerated aging><accelerated biological age><accelerated biological aging><adulthood><advisory team><age acceleration><ages><alcohol-exposed pregnancy><bio-markers><biologic marker><biomarker><clinical practice><cohort><conference><convention><cost><cytokine><data base><data dictionary><data management><data sharing><diabetes><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><dissemination of results><drinking><e-Health><eHealth><electronic health><epidemiology research study><epidemiology study><epidemiology survey><exposed to alcohol prenatally><faces><facial><falls><fetal><fetal diagnosis><forging><gestation ETOH exposure><gestation alcohol exposure><gestation ethanol exposure><gestational ethanol exposure><health care service><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation efforts><implementation science><improved><innovate><innovation><innovative><life span><lifespan><maternal alcohol consumption><maternal alcohol drinking><maternal alcohol ingestion><maternal alcohol use><maternal ethanol use><meeting><meetings><member><miRNA><multidisciplinary><neurobehavioral><news><novel><online screening><outreach><pathophysiology><pre-clinical research><pre-clinical study><preclinical research><preclinical study><pregnancy ETOH exposure><pregnancy alcohol exposure><pregnancy ethanol exposure><prenatal alcohol effect><prenatally alcohol exposed><prenatally exposed to alcohol><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><screening><screenings><social role><summit><symposia><symposium><three dimensional><tool><web site><website>
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Jessica A Baker

SAN DIEGO STATE UNIVERSITY, SAN DIEGO, CA

Good lead · 56/100
Training-friendly
Very recent
Active award
Career award
$205,231
FY 2026

Project Title

Translational Research to Accelerate Interventions for Fetal Alcohol Spectrum Disorders: Evaluation of Physical Activity at Basic and Clinical Levels

Grant Number:

5K01AA031531-03

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Although identified over 50 years ago, there are a limited number of interventions for fetal alcohol spectrum disorders (FASD), the leading known preventable neurodevelopment disorders in the U.S. Neuropathology associated with prenatal alcohol exposure (PAE) alters behavioral, cogni...

Research Terms

<0-11 years old><ASD><Absolute ethanol><Acceleration><Accelerometer><Address><Adolescent><Adolescent Youth><Aerobic Activity><Aerobic Exercise><Aerobic Training><Aerobic fitness><Affect><Alcohol Chemical Class><Alcohols><Ammon Horn><Animal Model><Animal Models and Related Studies><Anxiety><Attention><Attenuated><Autism><Autistic Disorder><Award><Basic Research><Basic Science><Behavioral><Behavioral Paradigm><Blood Sample><Blood specimen><Brain><Brain Nervous System><Child><Child Youth><Childhood><Children (0-21)><Clinical><Clinical Data><Clinical Research><Clinical Sciences><Clinical Study><Clinical Treatment><Cognition><Cognitive><Common Rat Strains><Cornu Ammonis><Data><Data Set><Development><Diagnosis><Disease><Disorder><Dysfunction><ETOH><Early Infantile Autism><Emotional><Encephalon><Ethanol><Ethyl Alcohol><Evaluation><Exercise><FASD><Fetal Alcohol Exposure><Fetal Alcohol Spectrum Disorder><Fetal ETOH Exposure><Fetal Ethanol Exposure><Fetal alcohol effects><Functional disorder><Funding><Goals><Grain Alcohol><Health><Health Benefit><Hippocampus><History><Hyperactivity><Immune><Immune Markers><Immunes><Immunologic Markers><Impairment><In Utero Alcohol Exposure><In Utero ETOH Exposure><In Utero Ethanol Exposure><Individual><Infantile Autism><Intervention><Intervention Studies><Investigators><Kanner's Syndrome><Language><Learning><Life><Locomotor Activity><Longitudinal Studies><Longitudinal Surveys><Measures><Memory><Mental Depression><Mental Health><Mental Hygiene><Mentorship><Methylcarbinol><Modeling><Molecular><Motor><Motor Activity><NIAAA><NIH><National Institute on Alcohol Abuse and Alcoholism><National Institutes of Health><Neural Development><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurocognition><Neurodevelopmental Disorder><Neuroimmune><Neurological Development Disorder><Outcome><Pattern><Physical activity><Physiopathology><Population><Preclinical data><Prenatal Alcohol Exposure><Prenatal ETOH Exposure><Prenatal Ethanol Exposure><Psychological Health><Public Health><Questionnaires><Rat><Rats Mammals><Rattus><Recording of previous events><Research><Research Personnel><Research Support><Research Training><Researchers><Rodent Model><Running><Sampling><Strategic Planning><Survey Instrument><Surveys><Symptoms><Teratogenic effects><Testing><Therapeutic><Training><Translating><Translational Research><Translational Science><United States><United States National Institutes of Health><Variant><Variation><Youth><Youth 10-21><accelerometry><activity monitor><activity tracker><alcohol-exposed pregnancy><anxiety-like behavior><assess effectiveness><attenuate><attenuates><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><behavior test><behavioral test><career><clinical intervention><clinical relevance><clinical therapy><clinically relevant><cognitive development><cognitive function><cohort><depression><determine effectiveness><developmental><effectiveness assessment><effectiveness evaluation><emotional functioning><evaluate effectiveness><examine effectiveness><executive control><executive function><exercise intervention><experience><exposed to alcohol prenatally><gestation ETOH exposure><gestation alcohol exposure><gestation ethanol exposure><gestational ethanol exposure><hippocampal><histories><human data><immune-based biomarkers><immunological biomarkers><immunological markers><improved><improved outcome><innovate><innovation><innovative><intervention research><interventional research><interventional study><interventions research><juvenile><juvenile human><kids><life span><lifespan><long-term study><longitudinal outcome studies><longitudinal research study><model of animal><neurobehavioral><neurodevelopment><neurodevelopmental disease><neurogenesis><neuropathologic><neuropathological><neuropathology><neuroprotection><neuroprotective><neurotrophic factor><neurotrophin><neutrophin><pathophysiology><pediatric><physical activity intervention><post intervention><pre-clinical><pre-clinical research><preclinical><preclinical findings><preclinical information><preclinical research><pregnancy ETOH exposure><pregnancy alcohol exposure><pregnancy ethanol exposure><prenatal alcohol effect><prenatally alcohol exposed><prenatally exposed to alcohol><processing speed><programs><spatial memory><translation research><translational investigation><translational investigator><translational neuroscience><translational researcher><translational scientist><trial regimen><trial treatment><youngster><youth age>
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Stefan M. PULST

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$930,250
FY 2025

Project Title

Ataxin-2 complex proteins in neurodegeneration.

Grant Number:

5R35NS127253-04

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2022

End Date:

4/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract This R35 proposal builds on experiments supported by a Javits R37 and a U01 CREATE Bio award and the longstanding success of the principal investigator’s group leading from mechanistic discoveries in spinocerebellar ataxias and translation to novel treatments, one of which i...

Research Terms

<21+ years old><Address><Adult><Adult Human><Affect><Animal Model><Animal Models and Related Studies><Animals><Apoptotic><Ataxia><Ataxy><Autophagocytosis><Award><Behavioral><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cerebellar degeneration><Cessation of life><Chemicals><Complex><Coordination Impairment><Cytoplasm><Death><Degenerative Neurologic Disorders><Deterioration><Dimensions><Disease><Disorder><Dominantly-Inherited Spinocerebellar Ataxias><Dyssynergia><Environment><Foundations><Funding><Gene Targeting><Genes><Grant><Heat shock proteins><Hereditary><Human><In Vitro><Inherited><Intracellular Communication and Signaling><Laboratories><Mediating><Modeling><Modern Man><Morphology><Motor Cell><Motor Neuron Disease><Motor Neurons><Nerve Cells><Nerve Degeneration><Nerve Unit><Nervous System Degenerative Diseases><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neuron Degeneration><Neurons><Nutrient><Pathogenicity><Phase><Physiologic><Physiological><Poly Q><Principal Investigator><Proteins><Proteomics><Purkinje Cells><Purkinje's Corpuscles><RNA Transport><RNA metabolism><RNA-Binding Proteins><Regulation><Reproducibility><Research><Resource Sharing><Ribonucleic Acid Transport><Role><SCA2 protein><Scientist><Signal Transduction><Signal Transduction Systems><Signaling><Small RNA><Spinal><Spinocerebellar Ataxias><Spinocerebellar Atrophies><Stress><Techniques><Time><Translations><adulthood><ataxin-2><autophagy><biological signal transduction><cerebellar Purkinje cell><cerebellum degeneration><degenerative diseases of motor and sensory neurons><degenerative disorder of motor neurons><degenerative neurological diseases><diversity and inclusion><diversity and inclusivity><dosage><experiment><experimental research><experimental study><experiments><genome scale><genome-wide><genomewide><human model><in vivo><innovate><innovation><innovative><insight><model of animal><model of human><motoneuron><muscle strength><mutant><nerve cell death><nerve cell loss><neural degeneration><neurodegeneration><neurodegenerative><neurodegenerative illness><neurological degeneration><neuron cell death><neuron cell loss><neuron death><neuron loss><neuronal><neuronal cell death><neuronal cell loss><neuronal death><neuronal degeneration><neuronal loss><novel><polyQ><polyglutamine><protein complex><protein function><response><small molecule><social role><spinocerebellar ataxia type 2 gene product><stress protein><success><therapeutic target><tool><transcriptomics><translation>
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Robert michael Angelo

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$789,442
FY 2025

Project Title

Innate-adaptive immune bridging in gravidity-dependent immunity against placental malaria: a multi-omics approach

Grant Number:

1R01AI189963-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/17/2025

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Malaria in pregnancy is one of the leading causes of infant death globally. Placental malaria (PM) is the main mechanism by which malaria in pregnancy causes birth complications, such as preterm birth, stillbirth, and low birth weight. During PM, Plasmodium falciparum (Pf)-i...

Research Terms

<0-11 years old><2nd trimester><7S Gamma Globulin><Affect><Africa South of the Sahara><Allogenic><Antibodies><Automobile Driving><Birth><Blood><Blood Neutrophil><Blood Plasma><Blood Polymorphonuclear Neutrophil><Blood Reticuloendothelial System><Blood erythrocyte><Blood monocyte><Body Tissues><Cell Body><Cell-Mediated Cytolysis><Cell-Mediated Lympholysis><Cells><Cells Placenta-Tissue><Cellular Cytotoxicity><Child><Child Youth><Children (0-21)><Chondroitin 4 Sulfate><Chondroitin Sulfate A><Clinical><Clinical Trials><Cytotoxic cell><Enrollment><Equilibrium><Erythrocytes><Erythrocytic><Fetus><Gestation><Gravid><Gravidity><IgG><IgG Receptors><Immune><Immune Tolerance><Immune system><Immunes><Immunity><Immunoglobulin G><Immunoglobulin G Receptor><Immunologic Tolerance><Immunology><Infant Mortality><Infant Mortality Total><Infection><Infiltration><Inflammation><Inflammatory><K lymphocyte><Lead><Link><Low Birth Weight Infant><Lymphocyte Cytotoxicity><Lymphocytotoxicity><Macrophage><Malaria><Marrow Neutrophil><Marrow erythrocyte><Marrow monocyte><Maternal Mortality><Maternal-Fetal Exchange><Maternal-fetal medicine><Mediating><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Methods><Midtrimester><Modification><Myelogenous><Myeloid><Myeloid Cells><Mφ><NK Cells><Natural Killer Cells><Neonatal><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Normal Placentoma><P falciparum><P. falciparum><P.falciparum><Paludism><Parasitemia><Parasites><Parturition><Pathogenesis><Pathologic><Pb element><Perinatal Mortalities><Perinatal lethality><Perinatal mortality demographics><Peripheral><Phagocytes><Phagocytic Cell><Phagocytosis><Phenotype><Placenta><Placenta Embryonic Tissue><Placentome><Plasma><Plasma Serum><Plasmodium Infections><Plasmodium falciparum><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Pregnancy><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Production><Proteomics><Receptor Protein><Red Blood Cells><Red Cell><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Second Pregnancy Trimester><Second Trimester><Severities><Severity of illness><Shapes><Sub-Saharan Africa><Subsaharan Africa><Surface Proteins><Syncytiotrophoblast><Testing><Therapeutic><Tissues><Transplacental Exposure><Uganda><Variant><Variation><Woman><Work><acquired immunity><adverse birth outcomes><amebocyte><balance><balance function><biobank><biorepository><birth complications><blood corpuscles><cell mediated cytotoxicity><cell mediated immune response><death among infants><death in first year of life><death in infancy><death in infants><delivery complications><develop a vaccine><develop vaccines><development of a vaccine><disease severity><driving><enroll><expectant mother><expectant women><expecting mother><expecting women><fetal><gamma Fc Receptors><healthy pregnancy><heavy metal Pb><heavy metal lead><imaging approach><imaging based approach><immune system tolerance><immune unresponsiveness><immunological paralysis><improved><improved outcome><in vitro Model><individuals who are pregnant><infant death><infant demise><infantile death><kids><low birth weight><low birthweight><maternal death><maternal morbidity><maternal-fetal interface><monocyte><mortality in infants><multiomics><multiple omics><nanostring><neonatal outcome><neutrophil><novel><panomics><parasaetemia><people who are pregnant><perinatal deaths><perinatal morbidity><placenta infection><placental infection><placental malaria><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><preterm delivery><prevent><preventing><receptor><receptor binding><receptor bound><receptor expression><recruit><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><spatial relationship><stillbirth><stillborn><those who are pregnant><transcriptomics><vaccine development><women who are pregnant><youngster>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Prasanna Jagannathan

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$789,442
FY 2025

Project Title

Innate-adaptive immune bridging in gravidity-dependent immunity against placental malaria: a multi-omics approach

Grant Number:

1R01AI189963-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/17/2025

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Malaria in pregnancy is one of the leading causes of infant death globally. Placental malaria (PM) is the main mechanism by which malaria in pregnancy causes birth complications, such as preterm birth, stillbirth, and low birth weight. During PM, Plasmodium falciparum (Pf)-i...

Research Terms

<0-11 years old><2nd trimester><7S Gamma Globulin><Affect><Africa South of the Sahara><Allogenic><Antibodies><Automobile Driving><Birth><Blood><Blood Neutrophil><Blood Plasma><Blood Polymorphonuclear Neutrophil><Blood Reticuloendothelial System><Blood erythrocyte><Blood monocyte><Body Tissues><Cell Body><Cell-Mediated Cytolysis><Cell-Mediated Lympholysis><Cells><Cells Placenta-Tissue><Cellular Cytotoxicity><Child><Child Youth><Children (0-21)><Chondroitin 4 Sulfate><Chondroitin Sulfate A><Clinical><Clinical Trials><Cytotoxic cell><Enrollment><Equilibrium><Erythrocytes><Erythrocytic><Fetus><Gestation><Gravid><Gravidity><IgG><IgG Receptors><Immune><Immune Tolerance><Immune system><Immunes><Immunity><Immunoglobulin G><Immunoglobulin G Receptor><Immunologic Tolerance><Immunology><Infant Mortality><Infant Mortality Total><Infection><Infiltration><Inflammation><Inflammatory><K lymphocyte><Lead><Link><Low Birth Weight Infant><Lymphocyte Cytotoxicity><Lymphocytotoxicity><Macrophage><Malaria><Marrow Neutrophil><Marrow erythrocyte><Marrow monocyte><Maternal Mortality><Maternal-Fetal Exchange><Maternal-fetal medicine><Mediating><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Methods><Midtrimester><Modification><Myelogenous><Myeloid><Myeloid Cells><Mφ><NK Cells><Natural Killer Cells><Neonatal><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Normal Placentoma><P falciparum><P. falciparum><P.falciparum><Paludism><Parasitemia><Parasites><Parturition><Pathogenesis><Pathologic><Pb element><Perinatal Mortalities><Perinatal lethality><Perinatal mortality demographics><Peripheral><Phagocytes><Phagocytic Cell><Phagocytosis><Phenotype><Placenta><Placenta Embryonic Tissue><Placentome><Plasma><Plasma Serum><Plasmodium Infections><Plasmodium falciparum><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Pregnancy><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Production><Proteomics><Receptor Protein><Red Blood Cells><Red Cell><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Second Pregnancy Trimester><Second Trimester><Severities><Severity of illness><Shapes><Sub-Saharan Africa><Subsaharan Africa><Surface Proteins><Syncytiotrophoblast><Testing><Therapeutic><Tissues><Transplacental Exposure><Uganda><Variant><Variation><Woman><Work><acquired immunity><adverse birth outcomes><amebocyte><balance><balance function><biobank><biorepository><birth complications><blood corpuscles><cell mediated cytotoxicity><cell mediated immune response><death among infants><death in first year of life><death in infancy><death in infants><delivery complications><develop a vaccine><develop vaccines><development of a vaccine><disease severity><driving><enroll><expectant mother><expectant women><expecting mother><expecting women><fetal><gamma Fc Receptors><healthy pregnancy><heavy metal Pb><heavy metal lead><imaging approach><imaging based approach><immune system tolerance><immune unresponsiveness><immunological paralysis><improved><improved outcome><in vitro Model><individuals who are pregnant><infant death><infant demise><infantile death><kids><low birth weight><low birthweight><maternal death><maternal morbidity><maternal-fetal interface><monocyte><mortality in infants><multiomics><multiple omics><nanostring><neonatal outcome><neutrophil><novel><panomics><parasaetemia><people who are pregnant><perinatal deaths><perinatal morbidity><placenta infection><placental infection><placental malaria><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><preterm delivery><prevent><preventing><receptor><receptor binding><receptor bound><receptor expression><recruit><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><spatial relationship><stillbirth><stillborn><those who are pregnant><transcriptomics><vaccine development><women who are pregnant><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JENNY C-N CHANG

METHODIST HOSPITAL RESEARCH INSTITUTE, HOUSTON, TX

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$654,245
FY 2025

Project Title

Dual targeting of PI3K and NOS pathways in Metaplastic BreastCancer (MBC)

Grant Number:

5R01CA284315-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/8/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Metaplastic breast cancer (MpBC) is a rare subset accounting for <5% of all breast cancers. MpBC is a significant health challenge as it exhibits the most dismal prognosis of all breast cancer subtypes, worse than non-MpBC triple-negative breast cancer (TNBC), with median survival rate of 8...

Research Terms

<3-Phosphoinositide Dependent Protein Kinase-1><AKT><Accounting><Acetates><Adhesions><After Care><After-Treatment><Aftercare><Akt protein><Antioncogene Protein p53><Apoptosis><Apoptosis Pathway><Arginine><Biopsy><Breast Cancer><Breast Cancer Model><Breast Cancer Patient><Breast Cancer cell line><Breast PDX models><Breast Tumor Patient><Breast tumor cell line><Breast tumor model><Cancers><Catalytic Core><Catalytic Domain><Catalytic Region><Catalytic Site><Catalytic Subunit><Cell Body><Cell Communication><Cell Interaction><Cell Line><Cell Locomotion><Cell Migration><Cell Movement><Cell to Cell Communication and Signaling><Cell-Cell Signaling><Cell-to-Cell Interaction><CellLine><Cells><Cellular Expansion><Cellular Growth><Cellular Migration><Cellular Motility><Cellular Tumor Antigen P53><Chemoresistance><Clinical Trials><Combined Modality Therapy><Complement><Complement Proteins><Cytotoxic agent><Cytotoxic drug><D-NMMA><DNA mutation><Data><Data Analyses><Data Analysis><Detection><Development><Disease><Disorder><Drug resistance><Drugs><EDRF Synthase><Endocrine Therapy><Endogenous Nitrate Vasodilator><Endothelium-Derived Growth Factor Synthase><Endothelium-Derived Nitric Oxide><Environment><Event><Exhibits><Funding><General Prognostic Factor><Generalized Growth><Genes><Genetic Change><Genetic defect><Genetic mutation><Growth><Guanylyl Cyclase-Activating Factor Synthase><Health><Hormonal Therapy><INOS><Image><Immunocompetent><Immunofluorescence><Immunofluorescence Immunologic><Inducible Nitric Oxide Synthase><Inositide Phospholipids><Inositol Phosphoglycerides><Inositol Phospholipids><Invaded><Investigation><Isoforms><Kinases><L-Arginine><L-Monomethylarginine><L-NMMA><Lymphoid Cell><MMAC1><MMAC1 protein><Macrophage><Macrophage Nitric Oxide Synthase><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mediating><Medication><Metaplastic breast cancer><Metaplastic carcinoma of the breast><Metastasis><Metastasis to the Lung><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Neoplasm to the Lung><Metastatic Tumor><Metastatic Tumor to the Lung><Mice><Mice Mammals><Modeling><Molecular><Mononitrogen Monoxide><Multimodal Therapy><Multimodal Treatment><Murine><Mus><Mutate><Mutated in Multiple Advanced Cancers 1><Mutation><Myeloid Cells><Mφ><N(G)-Methylarginine><N(G)-Monomethyl-D-Arginine><N(G)-Monomethylarginine><N(omega)-Monomethyl-L-Arginine><N-Methylarginine><NG-Monomethyl-L-Arginine><NO Synthase><NOS2><NOS2A><NOS2A gene><NOS2A, Inducible, Hepatocyte><Neoplasm Metastasis><Nitric Oxide><Nitric Oxide Synthase><Nitric Oxide Synthase 2A><Nitric Oxide Synthetase Inhibitor><Nitric-Oxide Synthetase><Nitrogen Monoxide><Nitrogen Protoxide><Non-Polyadenylated RNA><Oncogenesis><Oncogenic><Oncoprotein p53><P53><PDX model><PHTS gene><PHTS protein><PI3K-Alpha><PIK3-Alpha><PIK3CA><PIK3CA gene><PIQRAY><PKB Kinase><PTEN><PTEN gene><PTEN protein><PTEN1><Pathway interactions><Patient derived xenograft><Patient-derived xenograft models of breast cancer><Patients><Pharmaceutical Preparations><Phosphatase and Tensin Homolog><Phosphatase and Tensin Homolog Deleted on Chromosome 10><Phosphatidyl Inositol><Phosphatidylinositol 3-Kinase, Catalytic, 110-kD, Alpha><Phosphatidylinositol 3-Kinase, Catalytic, Alpha><Phosphatidylinositols><Phosphoinositides><Phosphoprotein P53><Phosphoprotein pp53><Phosphotransferase Gene><Phosphotransferases><Population><Pre-Clinical Model><Preclinical Models><Primary Neoplasm><Primary Tumor><Production><Prognosis><Prognostic Factor><Prognostic/Survival Factor><Programmed Cell Death><Property><Protein Isoforms><Protein Kinase B><Protein TP53><Proto-Oncogene Proteins c-akt><PtdIns><Publishing><RAC-PK protein><RNA><RNA Gene Products><RNA Seq><RNA and protein interaction><RNA sequencing><RNA-Protein Interaction><RNAseq><Radiation therapy><Radiotherapeutics><Radiotherapy><Refractory><Regimen><Research Specimen><Resistance><Resolution><Ribo-seq><Ribonucleic Acid><Ribosomal Proteins><Ribosomes><Role><SUM-159><SUM-159 Breast Cancer Cell Line><SUM159><Secondary Neoplasm><Secondary Tumor><Signal Pathway><Specimen><Strains Cell Lines><Stromal Cells><Survey Instrument><Surveys><Survival Rate><TNBC><TP53><TP53 gene><TRP53><Testing><Therapeutic><Tissue Growth><Translations><Transphosphorylases><Treatment Efficacy><Tumor Cell><Tumor Protein p53><Tumor Protein p53 Gene><alpelisib><breast cancer PDX><breast cancer patient-derived xenograft><c-akt protein><cancer metastasis><cancer microenvironment><cancer sub-types><cancer subtypes><cell growth><cell motility><cell type><chemoresistant><chemotherapy><chemotherapy resistance><chemotherapy resistant><clinical prognosis><combination therapy><combinatorial><combined modality treatment><combined treatment><complementation><cultured cell line><data interpretation><determine efficacy><developmental><drug resistant><drug/agent><druggable target><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><endothelial cell derived relaxing factor><evaluate efficacy><examine efficacy><gain of function><genome mutation><hPDK1><hormone therapy><imaging><imaging system><immune competent><in vivo><individuals with breast cancer><inhibitor><intercellular communication><intervention efficacy><lung metastasis><malignancy><malignant breast tumor><mammary cancer model><mammary tumor model><metastasize to the lung><mouse model><multi-modal data><multi-modal datasets><multi-modal therapy><multi-modal treatment><multimodal data><multimodal datasets><murine model><mutated in multiple advanced cancers 1 protein><neoplasm/cancer><neoplastic cell><nitric oxide synthase inhibitor><omega-N-Methylarginine><ontogeny><outcome prediction><p110-Alpha><p53 Antigen><p53 Genes><p53 Tumor Suppressor><participant enrollment><pathway><patient derived xenograft model><patient enrollment><patients with breast cancer><person with breast cancer><phosphatase and tensin homologue on chromosome ten><post treatment><pre-clinical><preclinical><progenitor cell regeneration><progenitor cell self renewal><progenitor regeneration><progenitor self renewal><protein kinase B kinase><protein p53><proto-oncogene protein RAC><proto-oncogene protein akt><pulmonary metastasis><rac protein kinase><radiation treatment><related to A and C-protein><resistance to Drug><resistance to therapy><resistant><resistant to Drug><resistant to therapy><resolutions><response><response to therapy><response to treatment><ribosome footprint profiling><ribosome profiling><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stem and progenitor cell regeneration><stem and progenitor cell self renewal><stem cell regeneration><stem cell self renewal><taxane><therapeutic efficacy><therapeutic resistance><therapeutic response><therapeutically effective><therapy efficacy><therapy resistant><therapy response><transcriptome sequencing><transcriptomic sequencing><translation><treatment resistance><treatment response><treatment responsiveness><treatment with radiation><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor cell metastasis><tumor growth><tumor microenvironment><tumorigenesis>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

STEVEN FIERING

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$620,922
FY 2025

Project Title

Toward translation of a plant virus-based in situ vaccination nanotechnology

Grant Number:

5R01CA274640-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/22/2022

End Date:

7/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Summary This R01, submitted to the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program, is a continuation of our successful U01 CA218292 (09/2017-07/2022), funded through the NCI Alliance for Nanotechnology in Cancer program. During the U01 project period, we demonstrated that ...

Research Terms

<Abscopal effect><Antigens><Antitumor Response><Applications Grants><Award><B16F10><Biodistribution><Biological><Biological Markers><Biopsy><Biotech><Biotechnology><Blood><Blood Reticuloendothelial System><Breast Cancer><Cancer Intervention><Cancers><Canine Species><Canis familiaris><Cell Body><Cells><Chemistry><Chromatography><Chronic><Clinical><Clinical Trials><Collaborations><Cowpea Mosaic Viruses><Data><Development><Disease remission><Dogs><Dogs Mammals><Dose><Enrollment><Environment><Evaluation><Experimental Therapies><Fabaceae><Farm><Feces><Formulation><Foundations><Funding><Future><Genomics><Goals><Good Manufacturing Process><Good manufacturing practice><Grant Proposals><Human><Image><Immune><Immune mediated therapy><Immune memory><Immune system><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Memory><Immunologic Stimulation><Immunological><Immunological Memory><Immunological Stimulation><Immunologically><Immunologically Directed Therapy><Immunologics><Immunostimulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><Industry Standard><Inflammation><Injections><Innate Immune System><Intellectual Property><Investigation><Investigational Therapies><Investigational Treatments><Leadership><Legumes><Leguminosae><Leguminoseae><Licensing><Malignant Breast Neoplasm><Malignant Melanoma><Malignant Neoplasms><Malignant Soft Tissue Neoplasm><Malignant Tumor><Mammalia><Mammals><Mast Cell Neoplasm><Mast Cell Proliferative Disease><Mast Cells Tumor><Mastocytoma><Mediating><Melanoma><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Methodology><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Monitor><Mosaic Viruses><Murine><Mus><Nanotechnology><Nanovirus><Neoplasm Metastasis><Oncogenic Viruses><Oncology><Oncology Cancer><Organ><Patients><Personalized medical approach><Pharmacology><Pharmacology and Toxicology><Phase 0 Clinical Trial><Plant Viruses><Plants><Position><Positioning Attribute><Production><Protocol><Protocols documentation><Recurrence><Recurrent><Remission><Safety><Sarcoma><Secondary Neoplasm><Secondary Tumor><Site><Structure><TM-MKR><Techniques><Technology><Time><Toxic effect><Toxicities><Toxicology><Translating><Translational Research><Translational Science><Translations><Tumor Antigens><Tumor Burden><Tumor Cell><Tumor Immunity><Tumor Load><Tumor Markers><Tumor Viruses><Tumor-Associated Antigen><Urine><VAC-TX><Vaccine Therapy><abscopal activity><abscopal response><anamnestic reaction><anti-cancer immunotherapy><anti-tumor immune response><anti-tumor immunity><anti-tumor response><anticancer immunotherapy><antitumor immunity><arm><bio-markers><biologic><biologic marker><biomarker><cancer antigens><cancer immunity><cancer immunology><cancer immunotherapy><cancer metastasis><cancer microenvironment><canine><cell killing><clinical practice><companion dog><cowpea virus><developmental><domestic dog><drug candidate><engineered immune system><enroll><experience><experimental therapeutic agents><experimental therapeutics><imaging><immune engineering><immune suppression><immune suppressive activity><immune suppressive function><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapies><immune-based treatments><immuno therapy><immunoengineering><immunogen><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunotherapy for cancer><immunotherapy of cancer><immunotherapy trials><improved><in situ vaccination><in situ vaccine><individualized approach><intervention program><malignancy><malignant breast tumor><malignant soft tissue tumor><manufacture><manufacturing facility><manufacturing plants><melanoma cancer model><melanoma model><melanoma tumor model><method development><mosaic><mouse model><murine model><nano particle><nano tech><nano technology><nano virus><nano-sized particle><nano-technological><nanoparticle><nanosized particle><nanotech><nanotechnological><neo-antigen><neo-epitopes><neoantigens><neoepitopes><neoplasm immunology><neoplasm/cancer><neoplastic cell><oncogenic tumor virus><oncology trial><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><pea family><personalized approach><precision approach><prevent><preventing><production plants><programs><recruit><residence><residential building><residential site><response to therapy><response to treatment><secondary immune response><stool><success><systemic toxicity><tailored approach><therapeutic response><therapeutic vaccination><therapy response><translation><translation research><translational investigation><treatment response><treatment responsiveness><tumor><tumor biomarker><tumor cell metastasis><tumor immunology><tumor microenvironment><tumor specific biomarker><tumor-specific antigen><vaccine candidate>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ashish Ranjan

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$620,922
FY 2025

Project Title

Toward translation of a plant virus-based in situ vaccination nanotechnology

Grant Number:

5R01CA274640-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/22/2022

End Date:

7/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Summary This R01, submitted to the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program, is a continuation of our successful U01 CA218292 (09/2017-07/2022), funded through the NCI Alliance for Nanotechnology in Cancer program. During the U01 project period, we demonstrated that ...

Research Terms

<Abscopal effect><Antigens><Antitumor Response><Applications Grants><Award><B16F10><Biodistribution><Biological><Biological Markers><Biopsy><Biotech><Biotechnology><Blood><Blood Reticuloendothelial System><Breast Cancer><Cancer Intervention><Cancers><Canine Species><Canis familiaris><Cell Body><Cells><Chemistry><Chromatography><Chronic><Clinical><Clinical Trials><Collaborations><Cowpea Mosaic Viruses><Data><Development><Disease remission><Dogs><Dogs Mammals><Dose><Enrollment><Environment><Evaluation><Experimental Therapies><Fabaceae><Farm><Feces><Formulation><Foundations><Funding><Future><Genomics><Goals><Good Manufacturing Process><Good manufacturing practice><Grant Proposals><Human><Image><Immune><Immune mediated therapy><Immune memory><Immune system><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Memory><Immunologic Stimulation><Immunological><Immunological Memory><Immunological Stimulation><Immunologically><Immunologically Directed Therapy><Immunologics><Immunostimulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><Industry Standard><Inflammation><Injections><Innate Immune System><Intellectual Property><Investigation><Investigational Therapies><Investigational Treatments><Leadership><Legumes><Leguminosae><Leguminoseae><Licensing><Malignant Breast Neoplasm><Malignant Melanoma><Malignant Neoplasms><Malignant Soft Tissue Neoplasm><Malignant Tumor><Mammalia><Mammals><Mast Cell Neoplasm><Mast Cell Proliferative Disease><Mast Cells Tumor><Mastocytoma><Mediating><Melanoma><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Methodology><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Monitor><Mosaic Viruses><Murine><Mus><Nanotechnology><Nanovirus><Neoplasm Metastasis><Oncogenic Viruses><Oncology><Oncology Cancer><Organ><Patients><Personalized medical approach><Pharmacology><Pharmacology and Toxicology><Phase 0 Clinical Trial><Plant Viruses><Plants><Position><Positioning Attribute><Production><Protocol><Protocols documentation><Recurrence><Recurrent><Remission><Safety><Sarcoma><Secondary Neoplasm><Secondary Tumor><Site><Structure><TM-MKR><Techniques><Technology><Time><Toxic effect><Toxicities><Toxicology><Translating><Translational Research><Translational Science><Translations><Tumor Antigens><Tumor Burden><Tumor Cell><Tumor Immunity><Tumor Load><Tumor Markers><Tumor Viruses><Tumor-Associated Antigen><Urine><VAC-TX><Vaccine Therapy><abscopal activity><abscopal response><anamnestic reaction><anti-cancer immunotherapy><anti-tumor immune response><anti-tumor immunity><anti-tumor response><anticancer immunotherapy><antitumor immunity><arm><bio-markers><biologic><biologic marker><biomarker><cancer antigens><cancer immunity><cancer immunology><cancer immunotherapy><cancer metastasis><cancer microenvironment><canine><cell killing><clinical practice><companion dog><cowpea virus><developmental><domestic dog><drug candidate><engineered immune system><enroll><experience><experimental therapeutic agents><experimental therapeutics><imaging><immune engineering><immune suppression><immune suppressive activity><immune suppressive function><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapies><immune-based treatments><immuno therapy><immunoengineering><immunogen><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunotherapy for cancer><immunotherapy of cancer><immunotherapy trials><improved><in situ vaccination><in situ vaccine><individualized approach><intervention program><malignancy><malignant breast tumor><malignant soft tissue tumor><manufacture><manufacturing facility><manufacturing plants><melanoma cancer model><melanoma model><melanoma tumor model><method development><mosaic><mouse model><murine model><nano particle><nano tech><nano technology><nano virus><nano-sized particle><nano-technological><nanoparticle><nanosized particle><nanotech><nanotechnological><neo-antigen><neo-epitopes><neoantigens><neoepitopes><neoplasm immunology><neoplasm/cancer><neoplastic cell><oncogenic tumor virus><oncology trial><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><pea family><personalized approach><precision approach><prevent><preventing><production plants><programs><recruit><residence><residential building><residential site><response to therapy><response to treatment><secondary immune response><stool><success><systemic toxicity><tailored approach><therapeutic response><therapeutic vaccination><therapy response><translation><translation research><translational investigation><treatment response><treatment responsiveness><tumor><tumor biomarker><tumor cell metastasis><tumor immunology><tumor microenvironment><tumor specific biomarker><tumor-specific antigen><vaccine candidate>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nicole Franziska Steinmetz

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$620,922
FY 2025

Project Title

Toward translation of a plant virus-based in situ vaccination nanotechnology

Grant Number:

5R01CA274640-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/22/2022

End Date:

7/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Summary This R01, submitted to the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program, is a continuation of our successful U01 CA218292 (09/2017-07/2022), funded through the NCI Alliance for Nanotechnology in Cancer program. During the U01 project period, we demonstrated that ...

Research Terms

<Abscopal effect><Antigens><Antitumor Response><Applications Grants><Award><B16F10><Biodistribution><Biological><Biological Markers><Biopsy><Biotech><Biotechnology><Blood><Blood Reticuloendothelial System><Breast Cancer><Cancer Intervention><Cancers><Canine Species><Canis familiaris><Cell Body><Cells><Chemistry><Chromatography><Chronic><Clinical><Clinical Trials><Collaborations><Cowpea Mosaic Viruses><Data><Development><Disease remission><Dogs><Dogs Mammals><Dose><Enrollment><Environment><Evaluation><Experimental Therapies><Fabaceae><Farm><Feces><Formulation><Foundations><Funding><Future><Genomics><Goals><Good Manufacturing Process><Good manufacturing practice><Grant Proposals><Human><Image><Immune><Immune mediated therapy><Immune memory><Immune system><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Memory><Immunologic Stimulation><Immunological><Immunological Memory><Immunological Stimulation><Immunologically><Immunologically Directed Therapy><Immunologics><Immunostimulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><Industry Standard><Inflammation><Injections><Innate Immune System><Intellectual Property><Investigation><Investigational Therapies><Investigational Treatments><Leadership><Legumes><Leguminosae><Leguminoseae><Licensing><Malignant Breast Neoplasm><Malignant Melanoma><Malignant Neoplasms><Malignant Soft Tissue Neoplasm><Malignant Tumor><Mammalia><Mammals><Mast Cell Neoplasm><Mast Cell Proliferative Disease><Mast Cells Tumor><Mastocytoma><Mediating><Melanoma><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Methodology><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Monitor><Mosaic Viruses><Murine><Mus><Nanotechnology><Nanovirus><Neoplasm Metastasis><Oncogenic Viruses><Oncology><Oncology Cancer><Organ><Patients><Personalized medical approach><Pharmacology><Pharmacology and Toxicology><Phase 0 Clinical Trial><Plant Viruses><Plants><Position><Positioning Attribute><Production><Protocol><Protocols documentation><Recurrence><Recurrent><Remission><Safety><Sarcoma><Secondary Neoplasm><Secondary Tumor><Site><Structure><TM-MKR><Techniques><Technology><Time><Toxic effect><Toxicities><Toxicology><Translating><Translational Research><Translational Science><Translations><Tumor Antigens><Tumor Burden><Tumor Cell><Tumor Immunity><Tumor Load><Tumor Markers><Tumor Viruses><Tumor-Associated Antigen><Urine><VAC-TX><Vaccine Therapy><abscopal activity><abscopal response><anamnestic reaction><anti-cancer immunotherapy><anti-tumor immune response><anti-tumor immunity><anti-tumor response><anticancer immunotherapy><antitumor immunity><arm><bio-markers><biologic><biologic marker><biomarker><cancer antigens><cancer immunity><cancer immunology><cancer immunotherapy><cancer metastasis><cancer microenvironment><canine><cell killing><clinical practice><companion dog><cowpea virus><developmental><domestic dog><drug candidate><engineered immune system><enroll><experience><experimental therapeutic agents><experimental therapeutics><imaging><immune engineering><immune suppression><immune suppressive activity><immune suppressive function><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapies><immune-based treatments><immuno therapy><immunoengineering><immunogen><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunotherapy for cancer><immunotherapy of cancer><immunotherapy trials><improved><in situ vaccination><in situ vaccine><individualized approach><intervention program><malignancy><malignant breast tumor><malignant soft tissue tumor><manufacture><manufacturing facility><manufacturing plants><melanoma cancer model><melanoma model><melanoma tumor model><method development><mosaic><mouse model><murine model><nano particle><nano tech><nano technology><nano virus><nano-sized particle><nano-technological><nanoparticle><nanosized particle><nanotech><nanotechnological><neo-antigen><neo-epitopes><neoantigens><neoepitopes><neoplasm immunology><neoplasm/cancer><neoplastic cell><oncogenic tumor virus><oncology trial><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><pea family><personalized approach><precision approach><prevent><preventing><production plants><programs><recruit><residence><residential building><residential site><response to therapy><response to treatment><secondary immune response><stool><success><systemic toxicity><tailored approach><therapeutic response><therapeutic vaccination><therapy response><translation><translation research><translational investigation><treatment response><treatment responsiveness><tumor><tumor biomarker><tumor cell metastasis><tumor immunology><tumor microenvironment><tumor specific biomarker><tumor-specific antigen><vaccine candidate>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Vijay Krishnamoorthy

DUKE UNIVERSITY, DURHAM, NC

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$599,123
FY 2025

Project Title

Impact of Autonomic Dysfunction on Multi-Organ Dysfunction following Severe TBI: The AUTO-BOOST Study

Grant Number:

5R01NS130832-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2023

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Traumatic brain injury (TBI) is a major public health concern, affecting more than 1.5 million individuals annually in the United States. Extracranial multi-organ dysfunction (MODS) occurs in approximately 60% of severe TBI patients and contributes to secondary brain injurie...

Research Terms

<21+ years old><AGE receptor><Acquired brain injury><Address><Admission><Admission activity><Adult><Adult Human><Affect><Age><Ancillary Study><Arterial Stretch Receptors><Arteries><Autonomic Dysfunction><Autonomic nervous system><Baroreceptors><Biological Markers><Brain><Brain Injuries><Brain Nervous System><Brain Trauma><Cardiac><Cell Communication and Signaling><Cell Signaling><Cephalic><Cerebrum><Cessation of life><Clinical><Clinical Data><Clinical Trials><Cohort Studies><Complex><Concurrent Studies><Cranial><Critical Care><Data><Death><Development><Dysfunction><ED visit><ER visit><Elevated Intracranial Pressure><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Encephalon><Frequencies><Functional disorder><Future><Glasgow Outcome Scale><Goals><Guidelines><Heart Injuries><Hospital Admission><Hospitalization><Hour><Hypoxia><Hypoxic><Incidence><Individual><Inflammatory><Infrastructure><Injury><Injury to Kidney><Intracellular Communication and Signaling><Intracranial Hypertension><Intracranial Pressure><Intracranial Pressure Elevation><Intracranial Pressure Increase><Lung damage><Managed Care><Metabolic><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-site clinical trial><Multicenter clinical trial><Multisite clinical trial><Neurologic outcome><Neurological outcome><O element><O2 element><Organ><Organ failure><Outcome><Oxygen><Oxygen Deficiency><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Patients with traumatic brain injury><Performance><Physiopathology><Pilot Projects><Predicting Risk><Pressoreceptors><Prevalence><Public Health><RAGE receptor><Research><Secondary to><Sedation procedure><Signal Transduction><Signal Transduction Systems><Signaling><Standardization><Subarachnoid Pressure><Sympathetic Nervous System><TBI Patients><Telemetries><Telemetry><Testing><Traumatic Brain Injury><Troponin><United States><Vascular Stretch Receptors><adulthood><advanced glycosylation end product receptor><ages><amphoterin receptor><bio-markers><biologic marker><biological signal transduction><biomarker><brain damage><brain tissue><brain-injured><cardiac injury><cerebral><cerebral hypoperfusion><clinical care><clinical efficacy><cohort><computer based prediction><cystatin C><death risk><develop therapy><developmental><forecasting risk><functional outcomes><heart rate variability><hemodynamics><high risk><improved><improved outcome><indexing><injuries><injury to organs><injury-related death><intervention development><kidney injury><lung injury><mortality risk><organ injury><participant enrollment><pathophysiology><patient enrollment><patient oriented outcomes><phase 3 trial><phase III trial><pilot study><post gamma-globulins><post-gamma-protein><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predicts risk><pressure><prevent><preventing><pulmonary damage><pulmonary injury><pulmonary tissue damage><pulmonary tissue injury><raised ICP><raised intracranial pressure><receptor for AGE><receptor for advanced glycation end product><receptor for advanced glycation endproducts><receptor of AGE><renal injury><risk prediction><risk predictions><sedation><sex><telemetric><therapy development><traumatic brain damage><traumatic brain injury patients><treatment development><treatment strategy>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph Benjamin Miller

DUKE UNIVERSITY, DURHAM, NC

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$599,123
FY 2025

Project Title

Impact of Autonomic Dysfunction on Multi-Organ Dysfunction following Severe TBI: The AUTO-BOOST Study

Grant Number:

5R01NS130832-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2023

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Traumatic brain injury (TBI) is a major public health concern, affecting more than 1.5 million individuals annually in the United States. Extracranial multi-organ dysfunction (MODS) occurs in approximately 60% of severe TBI patients and contributes to secondary brain injurie...

Research Terms

<21+ years old><AGE receptor><Acquired brain injury><Address><Admission><Admission activity><Adult><Adult Human><Affect><Age><Ancillary Study><Arterial Stretch Receptors><Arteries><Autonomic Dysfunction><Autonomic nervous system><Baroreceptors><Biological Markers><Brain><Brain Injuries><Brain Nervous System><Brain Trauma><Cardiac><Cell Communication and Signaling><Cell Signaling><Cephalic><Cerebrum><Cessation of life><Clinical><Clinical Data><Clinical Trials><Cohort Studies><Complex><Concurrent Studies><Cranial><Critical Care><Data><Death><Development><Dysfunction><ED visit><ER visit><Elevated Intracranial Pressure><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Encephalon><Frequencies><Functional disorder><Future><Glasgow Outcome Scale><Goals><Guidelines><Heart Injuries><Hospital Admission><Hospitalization><Hour><Hypoxia><Hypoxic><Incidence><Individual><Inflammatory><Infrastructure><Injury><Injury to Kidney><Intracellular Communication and Signaling><Intracranial Hypertension><Intracranial Pressure><Intracranial Pressure Elevation><Intracranial Pressure Increase><Lung damage><Managed Care><Metabolic><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-site clinical trial><Multicenter clinical trial><Multisite clinical trial><Neurologic outcome><Neurological outcome><O element><O2 element><Organ><Organ failure><Outcome><Oxygen><Oxygen Deficiency><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Patients with traumatic brain injury><Performance><Physiopathology><Pilot Projects><Predicting Risk><Pressoreceptors><Prevalence><Public Health><RAGE receptor><Research><Secondary to><Sedation procedure><Signal Transduction><Signal Transduction Systems><Signaling><Standardization><Subarachnoid Pressure><Sympathetic Nervous System><TBI Patients><Telemetries><Telemetry><Testing><Traumatic Brain Injury><Troponin><United States><Vascular Stretch Receptors><adulthood><advanced glycosylation end product receptor><ages><amphoterin receptor><bio-markers><biologic marker><biological signal transduction><biomarker><brain damage><brain tissue><brain-injured><cardiac injury><cerebral><cerebral hypoperfusion><clinical care><clinical efficacy><cohort><computer based prediction><cystatin C><death risk><develop therapy><developmental><forecasting risk><functional outcomes><heart rate variability><hemodynamics><high risk><improved><improved outcome><indexing><injuries><injury to organs><injury-related death><intervention development><kidney injury><lung injury><mortality risk><organ injury><participant enrollment><pathophysiology><patient enrollment><patient oriented outcomes><phase 3 trial><phase III trial><pilot study><post gamma-globulins><post-gamma-protein><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predicts risk><pressure><prevent><preventing><pulmonary damage><pulmonary injury><pulmonary tissue damage><pulmonary tissue injury><raised ICP><raised intracranial pressure><receptor for AGE><receptor for advanced glycation end product><receptor for advanced glycation endproducts><receptor of AGE><renal injury><risk prediction><risk predictions><sedation><sex><telemetric><therapy development><traumatic brain damage><traumatic brain injury patients><treatment development><treatment strategy>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Monica S Vavilala

DUKE UNIVERSITY, DURHAM, NC

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$599,123
FY 2025

Project Title

Impact of Autonomic Dysfunction on Multi-Organ Dysfunction following Severe TBI: The AUTO-BOOST Study

Grant Number:

5R01NS130832-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2023

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Traumatic brain injury (TBI) is a major public health concern, affecting more than 1.5 million individuals annually in the United States. Extracranial multi-organ dysfunction (MODS) occurs in approximately 60% of severe TBI patients and contributes to secondary brain injurie...

Research Terms

<21+ years old><AGE receptor><Acquired brain injury><Address><Admission><Admission activity><Adult><Adult Human><Affect><Age><Ancillary Study><Arterial Stretch Receptors><Arteries><Autonomic Dysfunction><Autonomic nervous system><Baroreceptors><Biological Markers><Brain><Brain Injuries><Brain Nervous System><Brain Trauma><Cardiac><Cell Communication and Signaling><Cell Signaling><Cephalic><Cerebrum><Cessation of life><Clinical><Clinical Data><Clinical Trials><Cohort Studies><Complex><Concurrent Studies><Cranial><Critical Care><Data><Death><Development><Dysfunction><ED visit><ER visit><Elevated Intracranial Pressure><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Encephalon><Frequencies><Functional disorder><Future><Glasgow Outcome Scale><Goals><Guidelines><Heart Injuries><Hospital Admission><Hospitalization><Hour><Hypoxia><Hypoxic><Incidence><Individual><Inflammatory><Infrastructure><Injury><Injury to Kidney><Intracellular Communication and Signaling><Intracranial Hypertension><Intracranial Pressure><Intracranial Pressure Elevation><Intracranial Pressure Increase><Lung damage><Managed Care><Metabolic><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-site clinical trial><Multicenter clinical trial><Multisite clinical trial><Neurologic outcome><Neurological outcome><O element><O2 element><Organ><Organ failure><Outcome><Oxygen><Oxygen Deficiency><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Patients with traumatic brain injury><Performance><Physiopathology><Pilot Projects><Predicting Risk><Pressoreceptors><Prevalence><Public Health><RAGE receptor><Research><Secondary to><Sedation procedure><Signal Transduction><Signal Transduction Systems><Signaling><Standardization><Subarachnoid Pressure><Sympathetic Nervous System><TBI Patients><Telemetries><Telemetry><Testing><Traumatic Brain Injury><Troponin><United States><Vascular Stretch Receptors><adulthood><advanced glycosylation end product receptor><ages><amphoterin receptor><bio-markers><biologic marker><biological signal transduction><biomarker><brain damage><brain tissue><brain-injured><cardiac injury><cerebral><cerebral hypoperfusion><clinical care><clinical efficacy><cohort><computer based prediction><cystatin C><death risk><develop therapy><developmental><forecasting risk><functional outcomes><heart rate variability><hemodynamics><high risk><improved><improved outcome><indexing><injuries><injury to organs><injury-related death><intervention development><kidney injury><lung injury><mortality risk><organ injury><participant enrollment><pathophysiology><patient enrollment><patient oriented outcomes><phase 3 trial><phase III trial><pilot study><post gamma-globulins><post-gamma-protein><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predicts risk><pressure><prevent><preventing><pulmonary damage><pulmonary injury><pulmonary tissue damage><pulmonary tissue injury><raised ICP><raised intracranial pressure><receptor for AGE><receptor for advanced glycation end product><receptor for advanced glycation endproducts><receptor of AGE><renal injury><risk prediction><risk predictions><sedation><sex><telemetric><therapy development><traumatic brain damage><traumatic brain injury patients><treatment development><treatment strategy>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PEDER M ANDERSEN

HENRY M. JACKSON FDN FOR THE ADV MIL/MED, BETHESDA, MD

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$423,626
FY 2025

Project Title

Mitigation of Radiation Induced Immune Dysfunction by PrC-210 Treatment

Grant Number:

5U01AI170033-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/17/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Mitigation of Radiation-Induced Immune Dysfunction by PrC-210 Treatment PROJECT SUMMARY Human risk of radiation exposure, possibly catastrophic in proportion, has risen. Whether from intentional or unintentional nuclear events, such events could yield thousands to hundreds of thousands of surviving ...

Research Terms

<Animals><Area><BMCELLTY><Bacterial Translocation><Biological Markers><Blood><Blood Cells><Blood Plasma><Blood Precursor Cell><Blood Reticuloendothelial System><Body Tissues><Body Weight><Bone Marrow><Bone Marrow Aspiration><Bone Marrow Cellularity><Bone Marrow Reticuloendothelial System><C57BL/6 Mouse><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cell Body><Cells><Cellular Immune Function><Chemotactic Cytokines><Chernobyl><Chernobyl Nuclear Accident><Chernobyl Nuclear Accident, Chornobyl, Ukraine, 1986><Chornobyl Nuclear Accident><Chornobyl Nuclear Disaster><Clinical Trials><Cytotoxic cell><Dendritic Cells><Disasters><Dose><Drug Kinetics><Emesis><Event><Exposure to><FITC-dextran><Female><Femur><Fukushima><Goals><Government><Growth Agents><Growth Factor><Growth Substances><Hematology><Hematopoietic Progenitor Cells><Hematopoietic stem cells><Histology><Homologous Chemotactic Cytokines><Human><Hypotension><Immune><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune infiltrates><Immune system><Immunes><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunology><Inflammation><Inflammatory><Injury><Intercrines><Ionizing Electromagnetic Radiation><Ionizing radiation><K lymphocyte><LD-50><LD50><Lethal Dose 50><Liver><Low Blood Pressure><Macrophage><Measurable><Measures><Medical><Mercaptans><Mercapto Compounds><Mice><Mice Mammals><Modeling><Modern Man><Mucosa><Mucosal Tissue><Mucous Membrane><Murine><Mus><Mφ><NK Cells><Natural Killer Cells><Nausea><Nuclear><Nuclear Accidents><Nuclear Reactors><Nuclear Weapon><Oral><Organ><Pathology><Peripheral Blood Cell><Pharmacokinetics><Plasma><Plasma Serum><Proteins Growth Factors><Proteome><Protocol><Protocols documentation><Radiation><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation exposure><Radiation induced damage><Radiation-Ionizing Total><Recovery><Regulatory T-Lymphocyte><Reporting><Research><Reticuloendothelial System, Serum, Plasma><Rodent><Rodentia><Rodents Mammals><Route><SIS cytokines><Site><Spleen><Spleen Reticuloendothelial System><Sulfhydryl Compounds><Survivors><T4 Cells><T4 Lymphocytes><T8 Cells><T8 Lymphocytes><Testing><Thiols><Thymus><Thymus Gland><Thymus Proper><Thymus Reticuloendothelial System><Time><Tissue Survival><Tissues><Total Body Irradiation><Treg><Vascular Hypotensive Disorder><Veiled Cells><Vomiting><Whole-Body Irradiation><Whole-Body Radiation><Work><aminothiol><bio-markers><biologic marker><biomarker><blood cell progenitor><blood progenitor><blood stem cell><blood-forming stem cell><chemoattractant cytokine><chemokine><cytokine><dirty bomb><exposed human population><fluorescein isothiocyanate dextran><fluoresceinthiocarbamoyl dextrans><gastrointestinal><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic progenitor><hemopoietic stem cell><hepatic body system><hepatic organ system><human exposure><immune cell infiltrate><immune function><improved><injuries><invention><ionizing output><irradiation><irradiation injury><jejunum><male><medical countermeasure><novel><nuclear disaster><nuclear event><nuclear incident><pharmacologic><pre-clinical development><preclinical development><protective effect><radiation countermeasure><radiation damage><radiation mitigation><radiation risk><radiological countermeasure><radiological mitigation><radiomitigation><regulatory T-cells><side effect><sulfhydryl group><urban environment><urban setting><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

WILLIAM E FAHL

HENRY M. JACKSON FDN FOR THE ADV MIL/MED, BETHESDA, MD

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$423,626
FY 2025

Project Title

Mitigation of Radiation Induced Immune Dysfunction by PrC-210 Treatment

Grant Number:

5U01AI170033-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/17/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Mitigation of Radiation-Induced Immune Dysfunction by PrC-210 Treatment PROJECT SUMMARY Human risk of radiation exposure, possibly catastrophic in proportion, has risen. Whether from intentional or unintentional nuclear events, such events could yield thousands to hundreds of thousands of surviving ...

Research Terms

<Animals><Area><BMCELLTY><Bacterial Translocation><Biological Markers><Blood><Blood Cells><Blood Plasma><Blood Precursor Cell><Blood Reticuloendothelial System><Body Tissues><Body Weight><Bone Marrow><Bone Marrow Aspiration><Bone Marrow Cellularity><Bone Marrow Reticuloendothelial System><C57BL/6 Mouse><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cell Body><Cells><Cellular Immune Function><Chemotactic Cytokines><Chernobyl><Chernobyl Nuclear Accident><Chernobyl Nuclear Accident, Chornobyl, Ukraine, 1986><Chornobyl Nuclear Accident><Chornobyl Nuclear Disaster><Clinical Trials><Cytotoxic cell><Dendritic Cells><Disasters><Dose><Drug Kinetics><Emesis><Event><Exposure to><FITC-dextran><Female><Femur><Fukushima><Goals><Government><Growth Agents><Growth Factor><Growth Substances><Hematology><Hematopoietic Progenitor Cells><Hematopoietic stem cells><Histology><Homologous Chemotactic Cytokines><Human><Hypotension><Immune><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune infiltrates><Immune system><Immunes><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunology><Inflammation><Inflammatory><Injury><Intercrines><Ionizing Electromagnetic Radiation><Ionizing radiation><K lymphocyte><LD-50><LD50><Lethal Dose 50><Liver><Low Blood Pressure><Macrophage><Measurable><Measures><Medical><Mercaptans><Mercapto Compounds><Mice><Mice Mammals><Modeling><Modern Man><Mucosa><Mucosal Tissue><Mucous Membrane><Murine><Mus><Mφ><NK Cells><Natural Killer Cells><Nausea><Nuclear><Nuclear Accidents><Nuclear Reactors><Nuclear Weapon><Oral><Organ><Pathology><Peripheral Blood Cell><Pharmacokinetics><Plasma><Plasma Serum><Proteins Growth Factors><Proteome><Protocol><Protocols documentation><Radiation><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation exposure><Radiation induced damage><Radiation-Ionizing Total><Recovery><Regulatory T-Lymphocyte><Reporting><Research><Reticuloendothelial System, Serum, Plasma><Rodent><Rodentia><Rodents Mammals><Route><SIS cytokines><Site><Spleen><Spleen Reticuloendothelial System><Sulfhydryl Compounds><Survivors><T4 Cells><T4 Lymphocytes><T8 Cells><T8 Lymphocytes><Testing><Thiols><Thymus><Thymus Gland><Thymus Proper><Thymus Reticuloendothelial System><Time><Tissue Survival><Tissues><Total Body Irradiation><Treg><Vascular Hypotensive Disorder><Veiled Cells><Vomiting><Whole-Body Irradiation><Whole-Body Radiation><Work><aminothiol><bio-markers><biologic marker><biomarker><blood cell progenitor><blood progenitor><blood stem cell><blood-forming stem cell><chemoattractant cytokine><chemokine><cytokine><dirty bomb><exposed human population><fluorescein isothiocyanate dextran><fluoresceinthiocarbamoyl dextrans><gastrointestinal><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic progenitor><hemopoietic stem cell><hepatic body system><hepatic organ system><human exposure><immune cell infiltrate><immune function><improved><injuries><invention><ionizing output><irradiation><irradiation injury><jejunum><male><medical countermeasure><novel><nuclear disaster><nuclear event><nuclear incident><pharmacologic><pre-clinical development><preclinical development><protective effect><radiation countermeasure><radiation damage><radiation mitigation><radiation risk><radiological countermeasure><radiological mitigation><radiomitigation><regulatory T-cells><side effect><sulfhydryl group><urban environment><urban setting><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sanchita P Ghosh

HENRY M. JACKSON FDN FOR THE ADV MIL/MED, BETHESDA, MD

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$423,626
FY 2025

Project Title

Mitigation of Radiation Induced Immune Dysfunction by PrC-210 Treatment

Grant Number:

5U01AI170033-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/17/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Mitigation of Radiation-Induced Immune Dysfunction by PrC-210 Treatment PROJECT SUMMARY Human risk of radiation exposure, possibly catastrophic in proportion, has risen. Whether from intentional or unintentional nuclear events, such events could yield thousands to hundreds of thousands of surviving ...

Research Terms

<Animals><Area><BMCELLTY><Bacterial Translocation><Biological Markers><Blood><Blood Cells><Blood Plasma><Blood Precursor Cell><Blood Reticuloendothelial System><Body Tissues><Body Weight><Bone Marrow><Bone Marrow Aspiration><Bone Marrow Cellularity><Bone Marrow Reticuloendothelial System><C57BL/6 Mouse><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cell Body><Cells><Cellular Immune Function><Chemotactic Cytokines><Chernobyl><Chernobyl Nuclear Accident><Chernobyl Nuclear Accident, Chornobyl, Ukraine, 1986><Chornobyl Nuclear Accident><Chornobyl Nuclear Disaster><Clinical Trials><Cytotoxic cell><Dendritic Cells><Disasters><Dose><Drug Kinetics><Emesis><Event><Exposure to><FITC-dextran><Female><Femur><Fukushima><Goals><Government><Growth Agents><Growth Factor><Growth Substances><Hematology><Hematopoietic Progenitor Cells><Hematopoietic stem cells><Histology><Homologous Chemotactic Cytokines><Human><Hypotension><Immune><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune infiltrates><Immune system><Immunes><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunology><Inflammation><Inflammatory><Injury><Intercrines><Ionizing Electromagnetic Radiation><Ionizing radiation><K lymphocyte><LD-50><LD50><Lethal Dose 50><Liver><Low Blood Pressure><Macrophage><Measurable><Measures><Medical><Mercaptans><Mercapto Compounds><Mice><Mice Mammals><Modeling><Modern Man><Mucosa><Mucosal Tissue><Mucous Membrane><Murine><Mus><Mφ><NK Cells><Natural Killer Cells><Nausea><Nuclear><Nuclear Accidents><Nuclear Reactors><Nuclear Weapon><Oral><Organ><Pathology><Peripheral Blood Cell><Pharmacokinetics><Plasma><Plasma Serum><Proteins Growth Factors><Proteome><Protocol><Protocols documentation><Radiation><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation exposure><Radiation induced damage><Radiation-Ionizing Total><Recovery><Regulatory T-Lymphocyte><Reporting><Research><Reticuloendothelial System, Serum, Plasma><Rodent><Rodentia><Rodents Mammals><Route><SIS cytokines><Site><Spleen><Spleen Reticuloendothelial System><Sulfhydryl Compounds><Survivors><T4 Cells><T4 Lymphocytes><T8 Cells><T8 Lymphocytes><Testing><Thiols><Thymus><Thymus Gland><Thymus Proper><Thymus Reticuloendothelial System><Time><Tissue Survival><Tissues><Total Body Irradiation><Treg><Vascular Hypotensive Disorder><Veiled Cells><Vomiting><Whole-Body Irradiation><Whole-Body Radiation><Work><aminothiol><bio-markers><biologic marker><biomarker><blood cell progenitor><blood progenitor><blood stem cell><blood-forming stem cell><chemoattractant cytokine><chemokine><cytokine><dirty bomb><exposed human population><fluorescein isothiocyanate dextran><fluoresceinthiocarbamoyl dextrans><gastrointestinal><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic progenitor><hemopoietic stem cell><hepatic body system><hepatic organ system><human exposure><immune cell infiltrate><immune function><improved><injuries><invention><ionizing output><irradiation><irradiation injury><jejunum><male><medical countermeasure><novel><nuclear disaster><nuclear event><nuclear incident><pharmacologic><pre-clinical development><preclinical development><protective effect><radiation countermeasure><radiation damage><radiation mitigation><radiation risk><radiological countermeasure><radiological mitigation><radiomitigation><regulatory T-cells><side effect><sulfhydryl group><urban environment><urban setting><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Vidya P. Kumar

HENRY M. JACKSON FDN FOR THE ADV MIL/MED, BETHESDA, MD

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$423,626
FY 2025

Project Title

Mitigation of Radiation Induced Immune Dysfunction by PrC-210 Treatment

Grant Number:

5U01AI170033-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/17/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Mitigation of Radiation-Induced Immune Dysfunction by PrC-210 Treatment PROJECT SUMMARY Human risk of radiation exposure, possibly catastrophic in proportion, has risen. Whether from intentional or unintentional nuclear events, such events could yield thousands to hundreds of thousands of surviving ...

Research Terms

<Animals><Area><BMCELLTY><Bacterial Translocation><Biological Markers><Blood><Blood Cells><Blood Plasma><Blood Precursor Cell><Blood Reticuloendothelial System><Body Tissues><Body Weight><Bone Marrow><Bone Marrow Aspiration><Bone Marrow Cellularity><Bone Marrow Reticuloendothelial System><C57BL/6 Mouse><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cell Body><Cells><Cellular Immune Function><Chemotactic Cytokines><Chernobyl><Chernobyl Nuclear Accident><Chernobyl Nuclear Accident, Chornobyl, Ukraine, 1986><Chornobyl Nuclear Accident><Chornobyl Nuclear Disaster><Clinical Trials><Cytotoxic cell><Dendritic Cells><Disasters><Dose><Drug Kinetics><Emesis><Event><Exposure to><FITC-dextran><Female><Femur><Fukushima><Goals><Government><Growth Agents><Growth Factor><Growth Substances><Hematology><Hematopoietic Progenitor Cells><Hematopoietic stem cells><Histology><Homologous Chemotactic Cytokines><Human><Hypotension><Immune><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune infiltrates><Immune system><Immunes><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunology><Inflammation><Inflammatory><Injury><Intercrines><Ionizing Electromagnetic Radiation><Ionizing radiation><K lymphocyte><LD-50><LD50><Lethal Dose 50><Liver><Low Blood Pressure><Macrophage><Measurable><Measures><Medical><Mercaptans><Mercapto Compounds><Mice><Mice Mammals><Modeling><Modern Man><Mucosa><Mucosal Tissue><Mucous Membrane><Murine><Mus><Mφ><NK Cells><Natural Killer Cells><Nausea><Nuclear><Nuclear Accidents><Nuclear Reactors><Nuclear Weapon><Oral><Organ><Pathology><Peripheral Blood Cell><Pharmacokinetics><Plasma><Plasma Serum><Proteins Growth Factors><Proteome><Protocol><Protocols documentation><Radiation><Radiation Dose><Radiation Dose Unit><Radiation Injuries><Radiation exposure><Radiation induced damage><Radiation-Ionizing Total><Recovery><Regulatory T-Lymphocyte><Reporting><Research><Reticuloendothelial System, Serum, Plasma><Rodent><Rodentia><Rodents Mammals><Route><SIS cytokines><Site><Spleen><Spleen Reticuloendothelial System><Sulfhydryl Compounds><Survivors><T4 Cells><T4 Lymphocytes><T8 Cells><T8 Lymphocytes><Testing><Thiols><Thymus><Thymus Gland><Thymus Proper><Thymus Reticuloendothelial System><Time><Tissue Survival><Tissues><Total Body Irradiation><Treg><Vascular Hypotensive Disorder><Veiled Cells><Vomiting><Whole-Body Irradiation><Whole-Body Radiation><Work><aminothiol><bio-markers><biologic marker><biomarker><blood cell progenitor><blood progenitor><blood stem cell><blood-forming stem cell><chemoattractant cytokine><chemokine><cytokine><dirty bomb><exposed human population><fluorescein isothiocyanate dextran><fluoresceinthiocarbamoyl dextrans><gastrointestinal><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic progenitor><hemopoietic stem cell><hepatic body system><hepatic organ system><human exposure><immune cell infiltrate><immune function><improved><injuries><invention><ionizing output><irradiation><irradiation injury><jejunum><male><medical countermeasure><novel><nuclear disaster><nuclear event><nuclear incident><pharmacologic><pre-clinical development><preclinical development><protective effect><radiation countermeasure><radiation damage><radiation mitigation><radiation risk><radiological countermeasure><radiological mitigation><radiomitigation><regulatory T-cells><side effect><sulfhydryl group><urban environment><urban setting><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

FRANCINE GRODSTEIN

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$423,087
FY 2025

Project Title

Mexican Teachers Cohort Study: Genetics and Cognitive Function

Grant Number:

3U01AG084547-02S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

This is a resubmission of a U01 application for the “Alzheimer’s Disease Sequencing Project (ADSP) Follow- Up Study 2.0: The Diverse Population Initiative” (PAR-21-212). The overall goals are to: (i) contribute nearly 20,000 GWAS and 5000 whole genome sequences to ADSP from participants of the “Estu...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD dementia><AD related dementia><ADRD><Active Follow-up><Address><Admixture><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Amerindian><Autopsy><Blood Sample><Blood specimen><Central American><Chicanas><Chicanos><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Collaborations><Complement><Complement Proteins><Concurrent Studies><DNA><Data><Dementia><Deoxyribonucleic Acid><Diagnosis><Disturbance in cognition><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Follow-Up Studies><Followup Studies><GWA study><GWAS><Genes><Genetic><Genetic Determinism><Genetic Diversity><Genetic Variation><Genome><Genomics><Genotype><Goals><Health><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Impaired cognition><Indigenous><Individual><Investigators><Length><Linkage Disequilibrium><Maps><Measures><Mexican><Mexican Americans><Mexico><Mitochondrial DNA><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Other Genetics><Participant><Pathologic><Pathway interactions><Pattern><Phenotype><Population><Population Heterogeneity><Primary Senile Degenerative Dementia><Process><Research><Research Personnel><Research Specimen><Research Support><Researchers><Resource Sharing><Sampling><Secondary to><South American><Specimen><Testing><Time><Universities><Variant><Variation><Woman><Women's cohort><above age 65><active followup><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><ancestry analysis><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><cognitive assessment><cognitive dysfunction><cognitive function><cognitive loss><cognitive testing><cohort><cohort in women><cohort on women><complementation><data harmonization><data hub><depository><design><designing><diverse populations><entire genome><ethnic subgroup><ethnicity group><experience><female cohort><follow up><follow-up><followed up><followup><full genome><genetic determinant><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><harmonized data><heterogeneous population><heteroplasmy><human old age (65+)><improved><men><mtDNA><necropsy><neuropathologic><neuropathological><neuropathology><novel><over 65 years><pathway><population diversity><postmortem><primary degenerative dementia><recruit><repository><screening><screenings><senile dementia of the Alzheimer type><sharing hub><social health determinants><teacher><telomere><trait><whole genome><whole genome association analysis><whole genome association study><younger age><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Martin Lajous

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$423,087
FY 2025

Project Title

Mexican Teachers Cohort Study: Genetics and Cognitive Function

Grant Number:

3U01AG084547-02S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

This is a resubmission of a U01 application for the “Alzheimer’s Disease Sequencing Project (ADSP) Follow- Up Study 2.0: The Diverse Population Initiative” (PAR-21-212). The overall goals are to: (i) contribute nearly 20,000 GWAS and 5000 whole genome sequences to ADSP from participants of the “Estu...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD dementia><AD related dementia><ADRD><Active Follow-up><Address><Admixture><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Amerindian><Autopsy><Blood Sample><Blood specimen><Central American><Chicanas><Chicanos><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Collaborations><Complement><Complement Proteins><Concurrent Studies><DNA><Data><Dementia><Deoxyribonucleic Acid><Diagnosis><Disturbance in cognition><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Follow-Up Studies><Followup Studies><GWA study><GWAS><Genes><Genetic><Genetic Determinism><Genetic Diversity><Genetic Variation><Genome><Genomics><Genotype><Goals><Health><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Impaired cognition><Indigenous><Individual><Investigators><Length><Linkage Disequilibrium><Maps><Measures><Mexican><Mexican Americans><Mexico><Mitochondrial DNA><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Other Genetics><Participant><Pathologic><Pathway interactions><Pattern><Phenotype><Population><Population Heterogeneity><Primary Senile Degenerative Dementia><Process><Research><Research Personnel><Research Specimen><Research Support><Researchers><Resource Sharing><Sampling><Secondary to><South American><Specimen><Testing><Time><Universities><Variant><Variation><Woman><Women's cohort><above age 65><active followup><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><ancestry analysis><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><cognitive assessment><cognitive dysfunction><cognitive function><cognitive loss><cognitive testing><cohort><cohort in women><cohort on women><complementation><data harmonization><data hub><depository><design><designing><diverse populations><entire genome><ethnic subgroup><ethnicity group><experience><female cohort><follow up><follow-up><followed up><followup><full genome><genetic determinant><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><harmonized data><heterogeneous population><heteroplasmy><human old age (65+)><improved><men><mtDNA><necropsy><neuropathologic><neuropathological><neuropathology><novel><over 65 years><pathway><population diversity><postmortem><primary degenerative dementia><recruit><repository><screening><screenings><senile dementia of the Alzheimer type><sharing hub><social health determinants><teacher><telomere><trait><whole genome><whole genome association analysis><whole genome association study><younger age><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dorota Skowronska-Krawczyk

UNIVERSITY OF CALIFORNIA-IRVINE, IRVINE, CA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$393,500
FY 2025

Project Title

Correlating Genomic AMD Risk Variants with Lipid Composition and Phagocytic Function of Patient-Derived Induced Pluripotent Stem Cell (iPSC)-derived Retinal Pigment Epithelium (RPE)

Grant Number:

3U01EY034594-03S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2022

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Supplementary Funding Request for U01 EY034594-01: "Correlating Genomic AMD Risk Variants with Lipid Composition and Phagocytic Function of Patient-Derived Induced Pluripotent Stem Cell (iPSC)- derived Retinal Pigment Epithelium (RPE)" The supplement instructions for PA-20-272 states the following: ...

Research Terms

<Funding><Genomics><Lipids><Outer pigmented layer of retina><Phagocytes><Phagocytic Cell><Pigment cell layer of retina><Pigmented layer of retina><Research><Retinal Pigment Epithelium><Retinal pigment epithelial cells><Risk-associated variant><Structure of retinal pigment epithelium><amebocyte><induced pluripotent stem cells derived from patients><induced pluripotent stem cells from patients><parent award><parent project><patient derived human iPS><patient derived human iPSC><patient derived human induced pluripotent stem cell><patient derived iPS><patient derived iPSC><patient derived induced pluripotent cells><patient derived induced pluripotent stem cells><patient-derived pluripotent stem cells><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><supplemental instruction><supplemental learning>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KARL J WAHLIN

UNIVERSITY OF CALIFORNIA-IRVINE, IRVINE, CA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$393,500
FY 2025

Project Title

Correlating Genomic AMD Risk Variants with Lipid Composition and Phagocytic Function of Patient-Derived Induced Pluripotent Stem Cell (iPSC)-derived Retinal Pigment Epithelium (RPE)

Grant Number:

3U01EY034594-03S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2022

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Supplementary Funding Request for U01 EY034594-01: "Correlating Genomic AMD Risk Variants with Lipid Composition and Phagocytic Function of Patient-Derived Induced Pluripotent Stem Cell (iPSC)- derived Retinal Pigment Epithelium (RPE)" The supplement instructions for PA-20-272 states the following: ...

Research Terms

<Funding><Genomics><Lipids><Outer pigmented layer of retina><Phagocytes><Phagocytic Cell><Pigment cell layer of retina><Pigmented layer of retina><Research><Retinal Pigment Epithelium><Retinal pigment epithelial cells><Risk-associated variant><Structure of retinal pigment epithelium><amebocyte><induced pluripotent stem cells derived from patients><induced pluripotent stem cells from patients><parent award><parent project><patient derived human iPS><patient derived human iPSC><patient derived human induced pluripotent stem cell><patient derived iPS><patient derived iPSC><patient derived induced pluripotent cells><patient derived induced pluripotent stem cells><patient-derived pluripotent stem cells><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><supplemental instruction><supplemental learning>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Matthew Galen Hartwig

DUKE UNIVERSITY, DURHAM, NC

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$392,751
FY 2025

Project Title

Clinical and Biological Factors Predicting Lung Transplant Textbook Outcomes (U01)

Grant Number:

5U01HL163300-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/5/2022

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT While lung transplantation is the only treatment option for end-stage lung disease, early post-operative complications are common and limit long-term patient survival while concomitantly increasing the economic burden of an already expensive therapy. Successful surgical outc...

Research Terms

<21+ years old><Abdomen><Acute><Address><Adopted><Adult><Adult Human><Aging><Assay><Bioassay><Biologic Factor><Biological><Biological Aging><Biological Assay><Biological Factors><Body System><Cell Body><Cells><Characteristics><Clinical><Collaborations><Complication><Country><Data><Data Coordinating Center><Data Coordination Center><Discipline><Dysfunction><Economic Burden><Enrollment><Failure><Freedom><Functional disorder><Funding Opportunities><Future><Geography><Goals><Graft Survival><Health system><Hospital Costs><Hospitalization cost><Immune><Immunes><Immunity><Individual><Infection><Intervention><Kidney Failure><Kidney Insufficiency><Liberty><Lung><Lung Diseases><Lung Grafting><Lung Respiratory System><Lung Transplantation><Machine Learning><Measurement><Measures><Minnesota><Modeling><Operative Procedures><Operative Surgical Procedures><Organ><Organ System><Orthopedic Surgery><Outcome><Output><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pennsylvania><Peptides><Performance><Perioperative><Perioperative complication><Physiologic><Physiological><Physiopathology><Position><Positioning Attribute><Postoperative><Postoperative Complications><Postoperative Period><Predictive Factor><Procedures><Process><Prospective cohort><Protocol><Protocols documentation><Provider><Publications><Publishing><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Graft><Pulmonary Transplant><Pulmonary Transplantation><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Renal Failure><Renal Insufficiency><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Resources><Risk><Risk Assessment><Risk Factors><Scientific Publication><Site><Surgical><Surgical Interventions><Surgical Procedure><Surrogate End Points><Surrogate Endpoint><Textbooks><Time><Transplant Recipients><Transplantation><Transplantation and Immune System><Universities><Viral><adulthood><biologic><biological age><biological process of age><clinical center><computer based prediction><cost><cytokine><disease of the lung><disorder of the lung><enroll><graft dysfunction><graft failure><improved><improved outcome><lung allograft><lung disorder><lung transplant><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><modifiable risk><novel><outcome prediction><participant enrollment><pathophysiology><patient enrollment><patient oriented outcomes><post-operative complications><predictive modeling><predictive tools><recruit><response><risk prediction algorithm><risk prediction model><senolytics><surgery><surgery outcome><surgical outcome><transplant><transplant centers><transplant patient>
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Laurie D Snyder

DUKE UNIVERSITY, DURHAM, NC

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$392,751
FY 2025

Project Title

Clinical and Biological Factors Predicting Lung Transplant Textbook Outcomes (U01)

Grant Number:

5U01HL163300-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/5/2022

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT While lung transplantation is the only treatment option for end-stage lung disease, early post-operative complications are common and limit long-term patient survival while concomitantly increasing the economic burden of an already expensive therapy. Successful surgical outc...

Research Terms

<21+ years old><Abdomen><Acute><Address><Adopted><Adult><Adult Human><Aging><Assay><Bioassay><Biologic Factor><Biological><Biological Aging><Biological Assay><Biological Factors><Body System><Cell Body><Cells><Characteristics><Clinical><Collaborations><Complication><Country><Data><Data Coordinating Center><Data Coordination Center><Discipline><Dysfunction><Economic Burden><Enrollment><Failure><Freedom><Functional disorder><Funding Opportunities><Future><Geography><Goals><Graft Survival><Health system><Hospital Costs><Hospitalization cost><Immune><Immunes><Immunity><Individual><Infection><Intervention><Kidney Failure><Kidney Insufficiency><Liberty><Lung><Lung Diseases><Lung Grafting><Lung Respiratory System><Lung Transplantation><Machine Learning><Measurement><Measures><Minnesota><Modeling><Operative Procedures><Operative Surgical Procedures><Organ><Organ System><Orthopedic Surgery><Outcome><Output><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pennsylvania><Peptides><Performance><Perioperative><Perioperative complication><Physiologic><Physiological><Physiopathology><Position><Positioning Attribute><Postoperative><Postoperative Complications><Postoperative Period><Predictive Factor><Procedures><Process><Prospective cohort><Protocol><Protocols documentation><Provider><Publications><Publishing><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Graft><Pulmonary Transplant><Pulmonary Transplantation><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Renal Failure><Renal Insufficiency><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Resources><Risk><Risk Assessment><Risk Factors><Scientific Publication><Site><Surgical><Surgical Interventions><Surgical Procedure><Surrogate End Points><Surrogate Endpoint><Textbooks><Time><Transplant Recipients><Transplantation><Transplantation and Immune System><Universities><Viral><adulthood><biologic><biological age><biological process of age><clinical center><computer based prediction><cost><cytokine><disease of the lung><disorder of the lung><enroll><graft dysfunction><graft failure><improved><improved outcome><lung allograft><lung disorder><lung transplant><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><modifiable risk><novel><outcome prediction><participant enrollment><pathophysiology><patient enrollment><patient oriented outcomes><post-operative complications><predictive modeling><predictive tools><recruit><response><risk prediction algorithm><risk prediction model><senolytics><surgery><surgery outcome><surgical outcome><transplant><transplant centers><transplant patient>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Cristina E Tognon

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$356,850
FY 2025

Project Title

Guidelines for processing and storing liquid biopsy samples for functional assays in research and clinical testing.

Grant Number:

5U01CA288669-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY The World Health Organization predicts that cancer diagnoses will increase to 22 million per year within the next two decades, with a corresponding 70% rise in cancer-related deaths. Liquid biopsy-based functional tests using blood and bone marrow will be crucial for advancing cance...

Research Terms

<AML - Acute Myeloid Leukemia><Acceleration><Acute Myeloblastic Leukemia><Acute Myelocytic Leukemia><Acute Myelogenous Leukemia><Adoption><Advanced Cancer><Advanced Malignant Neoplasm><Affect><Area><Assay><BMCELLTY><Benchmarking><Best Practice Analysis><Bioassay><Biological Assay><Biological Markers><Biopsy Sample><Biopsy Specimen><Blood><Blood Reticuloendothelial System><Bone Marrow><Bone Marrow Aspiration><Bone Marrow Cellularity><Bone Marrow Reticuloendothelial System><Bone marrow biopsy><Cancers><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cell Survival><Cell Viability><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cessation of life><Clinical><Clinical Evaluation><Clinical Testing><Clinical Trials><Collaborations><Collection><Cryofixation><Cryopreservation><Data><Data Set><Death><Detectable Residual Disease><Development><Drugs><Early Diagnosis><Effectiveness><Evaluation><Exhibits><Feedback><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Freezing><Goals><Guidelines><Hospitals><Image><Immunooncology><Impact evaluation><Industry><Institution><Intracellular Communication and Signaling><Investigators><Liquid substance><Malignant Neoplasms><Malignant Tumor><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measurable><Measurement><Measures><Medication><Methods><Minimal Residual Disease><Molecular Genetics><Outcome><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pharmaceutical Preparations><Phase><Phenotype><Practice Guidelines><Precision medicine trial><Private Sector><Process><Protein Array><Proteins><Quality Control><Reporting><Reproducibility><Research><Research Personnel><Research Specimen><Researchers><Residual Neoplasm><Residual Tumors><Retrieval><Retrospective Studies><Sampling><Scientist><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Factor Proto-Oncogene><Signaling Pathway Gene><Signaling Protein><Site><Specimen><Standardization><Subcellular Process><Techniques><Temperature><Test Result><Testing><Therapeutic><Time><Translating><Validation><Variant><Variation><Work><World Health Organization><acute granulocytic leukemia><acute myeloid leukemia><benchmark><bio-markers><biologic marker><biological signal transduction><biomarker><cancer diagnosis><cell imaging><cellular imaging><clinical decision-making><clinical implementation><clinical relevance><clinical research site><clinical site><clinical test><clinical translation><clinically relevant><clinically translatable><cold preservation><cold storage><data quality><developmental><drug development><drug sensitivity><drug/agent><early detection><flow cytophotometry><fluid><functional genomics><genomic data><genomic dataset><imaging><imaging platform><immune-oncology><immuno oncology><immunology oncology><improved><individualized cancer care><individualized oncology><knowledge base><leukemia><liquid><liquid biopsy><malignancy><neoplasm/cancer><next generation><novel><oncoimmunology><pathway><patient oriented outcomes><peripheral blood><personalization of treatment><personalized medicine><personalized oncology><personalized therapy><personalized treatment><precision cancer care><precision cancer medicine><precision medicine><precision medicine clinical trials><precision oncology><precision-based medicine><preservation><research clinical testing><residual disease><sample collection><specimen collection><success><therapeutic agent development><therapeutic development><validations>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tothu Q Vu

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$356,850
FY 2025

Project Title

Guidelines for processing and storing liquid biopsy samples for functional assays in research and clinical testing.

Grant Number:

5U01CA288669-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY The World Health Organization predicts that cancer diagnoses will increase to 22 million per year within the next two decades, with a corresponding 70% rise in cancer-related deaths. Liquid biopsy-based functional tests using blood and bone marrow will be crucial for advancing cance...

Research Terms

<AML - Acute Myeloid Leukemia><Acceleration><Acute Myeloblastic Leukemia><Acute Myelocytic Leukemia><Acute Myelogenous Leukemia><Adoption><Advanced Cancer><Advanced Malignant Neoplasm><Affect><Area><Assay><BMCELLTY><Benchmarking><Best Practice Analysis><Bioassay><Biological Assay><Biological Markers><Biopsy Sample><Biopsy Specimen><Blood><Blood Reticuloendothelial System><Bone Marrow><Bone Marrow Aspiration><Bone Marrow Cellularity><Bone Marrow Reticuloendothelial System><Bone marrow biopsy><Cancers><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cell Survival><Cell Viability><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cessation of life><Clinical><Clinical Evaluation><Clinical Testing><Clinical Trials><Collaborations><Collection><Cryofixation><Cryopreservation><Data><Data Set><Death><Detectable Residual Disease><Development><Drugs><Early Diagnosis><Effectiveness><Evaluation><Exhibits><Feedback><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Freezing><Goals><Guidelines><Hospitals><Image><Immunooncology><Impact evaluation><Industry><Institution><Intracellular Communication and Signaling><Investigators><Liquid substance><Malignant Neoplasms><Malignant Tumor><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measurable><Measurement><Measures><Medication><Methods><Minimal Residual Disease><Molecular Genetics><Outcome><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pharmaceutical Preparations><Phase><Phenotype><Practice Guidelines><Precision medicine trial><Private Sector><Process><Protein Array><Proteins><Quality Control><Reporting><Reproducibility><Research><Research Personnel><Research Specimen><Researchers><Residual Neoplasm><Residual Tumors><Retrieval><Retrospective Studies><Sampling><Scientist><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Factor Proto-Oncogene><Signaling Pathway Gene><Signaling Protein><Site><Specimen><Standardization><Subcellular Process><Techniques><Temperature><Test Result><Testing><Therapeutic><Time><Translating><Validation><Variant><Variation><Work><World Health Organization><acute granulocytic leukemia><acute myeloid leukemia><benchmark><bio-markers><biologic marker><biological signal transduction><biomarker><cancer diagnosis><cell imaging><cellular imaging><clinical decision-making><clinical implementation><clinical relevance><clinical research site><clinical site><clinical test><clinical translation><clinically relevant><clinically translatable><cold preservation><cold storage><data quality><developmental><drug development><drug sensitivity><drug/agent><early detection><flow cytophotometry><fluid><functional genomics><genomic data><genomic dataset><imaging><imaging platform><immune-oncology><immuno oncology><immunology oncology><improved><individualized cancer care><individualized oncology><knowledge base><leukemia><liquid><liquid biopsy><malignancy><neoplasm/cancer><next generation><novel><oncoimmunology><pathway><patient oriented outcomes><peripheral blood><personalization of treatment><personalized medicine><personalized oncology><personalized therapy><personalized treatment><precision cancer care><precision cancer medicine><precision medicine><precision medicine clinical trials><precision oncology><precision-based medicine><preservation><research clinical testing><residual disease><sample collection><specimen collection><success><therapeutic agent development><therapeutic development><validations>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Irene Sarosiek

TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO, EL PASO, TX

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$350,557
FY 2025

Project Title

A multicenter, double-blind, randomized, placebo- controlled, parallel study to assess the efficacy of 5- HT4 agonist prucalopride for the treatment of diabetic and idiopathic gastroparesis

Grant Number:

5U01DK074035-16

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2008

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Abstract In the clinical world of diagnosis and treatment options for the spectrum of gastroparesis (GP) symptoms, there are still numerous and challenging needs to understand, while at the same time further investigating the pathophysiology of this entity, which affects > 10 million of patients in ...

Research Terms

<5-HT><5-HT4 Receptor><5-Hydroxytryptamine><5-Hydroxytryptamine-4 Receptor><5HT><Abdominal Pain><Acceleration><Adverse Experience><Adverse event><Adverse reactions><Affect><Agonist><Antral><Biopsy><Body Tissues><Buspirone><Capsules><Causality><Chronic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Constipation><Control Groups><Diagnosis><Diagnostic><Diagnostic tests><Dissection><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drugs><Duodenum><Dysfunction><Emesis><Endoscopy><Enrollment><Enteramine><Etiology><Exhibits><FDA approved><Functional disorder><GI microbiota><Gamma Camera Imaging><Gastric Emptying><Gastric Stasis><Gastrointestinal microbiota><Gastroparesis><Grant><Hippophaine><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Individual><Investigation><Involuntary Muscle><Knowledge><Large Intestine><Laxative Preparation><Medical><Medication><Methodology><Methods><Motility><Mucosa><Mucosal Tissue><Mucous Membrane><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nausea><Operative Procedures><Operative Surgical Procedures><Outcome><PBMC><Pathogenesis><Pathologic><Patients><Peripheral Blood Mononuclear Cell><Pharmaceutical Preparations><Physiopathology><Placebo Control><Placebos><Population><Protocol><Protocols documentation><Pyloric Sphincters><Pyloric sphincter structure><Qualifying><Radioisotope Scanning><Radionuclide Imaging><Randomized><Reaction><Receptor Protein><Recommendation><Registries><Research><Research Design><Role><Safety><Sampling><Scintigraphy><Serotonin><Serotonin 4 Receptor><Serotonin Receptors 5-HT4><Severities><Sham Treatment><Small Intestines><Smooth Muscle><Stomach><Study Type><Subgroup><Submucosa><Surgical><Surgical Interventions><Surgical Procedure><Symptoms><Testing><Time><Tissue Sample><Tissues><Treatment Efficacy><Treatment Period><United States National Institutes of Health><Upper GI><Upper GI Tract><Upper Gastrointestinal Tract><Upper digestive tract structure><Vomiting><alleviate symptom><ameliorating symptom><capsule><causation><clinical care><clinical relevance><clinically relevant><cohort><decrease symptom><delayed gastric emptying><design><designing><determine efficacy><diabetic><diabetic gastroparesis><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease causation><drug/agent><dysbacteriosis><dysbiosis><dysbiotic><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><endoscopic imaging><enroll><enteric microbial community><enteric microbiota><evaluate efficacy><examine efficacy><fewer symptoms><gastric><gastric microbiota><gastrointestinal microbial flora><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiota><gut microbiotic><gut microflora><improve symptom><improved><insight><intervention efficacy><intestinal flora><intestinal microbiota><intestinal microflora><intestinal tract microflora><large bowel><laxative><meeting><meetings><microbial consortia><microbial flora><microbial imbalance><microbiota><microbiota composition><microflora><multispecies consortia><pathophysiology><pharmacologic><placebo controlled><radionuclide imaging/scanning><radionuclide scanning><randomisation><randomization><randomized placebo control trial><randomized placebo controlled trial><randomly assigned><receptor><reduce symptoms><relieves symptoms><response><sham therapy><small bowel><social role><stomach emptying><stomach microbiota><study design><surgery><symptom alleviation><symptom improvement><symptom reduction><symptom relief><symptomatic improvement><therapeutic efficacy><therapy efficacy><treatment days><treatment duration><wireless>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Solomon Fiifi Ofori-Acquah

KWAME NKRUMAH UNIVERSITY/SCIENCE/TECH, GHANA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$350,302
FY 2025

Project Title

Ghana-SPARCO: Ghana Sickle Pan-African Research Consortium

Grant Number:

5U01HL157004-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/10/2021

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Sickle Cell Disease (SCD) is a recessively inherited disorder characterized by disordered hemoglobin structure, aberrant endothelial interactions, systemic inflammation, oxidant stress, and activation of the coagulation system. These abnormalities underlie a myriad of complications i...

Research Terms

<0-11 years old><12-20 years old><21+ years old><Abnormal Hemoglobins><Acute><Address><Adolescence><Adolescent><Adolescent Youth><Adoption><Adult><Adult Human><Advocacy><Affect><Africa><Africa South of the Sahara><African><Agreement><Analgesic Agents><Analgesic Drugs><Analgesic Preparation><Analgesics><Anodynes><Antenatal Diagnosis><Antinociceptive Agents><Antinociceptive Drugs><Apoplexy><Area><Benchmarking><Best Practice Analysis><Blood Transfusion><Blood erythrocyte><Brain Vascular Accident><Capital><Caring><Causality><Cephalic><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Child><Child Youth><Children (0-21)><Chronic><Cities><Clinic><Clinical><Clotting><Coagulation><Coagulation Process><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Cohort Studies><Concurrent Studies><Consent><Country><Cranial><Data><Death><Death Rate><Decision Making><Disease><Disease Management><Disorder><Disorder Management><Disturbance in cognition><Drugs><Electronics><Endothelium><Enrollment><Erythrocytes><Erythrocytic><Ethics><Etiology><Event><Future><Genes><Genetic Diseases><Genotype><Ghana><Goals><Gold Coast><Grant><Guidelines><Harvest><Hb SS disease><HbSS disease><Health Care><Health Policy><Hematology><Hemoglobin><Hemoglobin S Disease><Hemoglobin sickle cell disease><Hemoglobin sickle cell disorder><Hemolytic Anemia><Hereditary Disease><Hospitals><Hydration><Hydration status><Hydroxycarbamid><Hydroxycarbamide><Impaired cognition><Inborn Genetic Diseases><Incidence><Individual><Infection><Infection prevention><Infrastructure><Inherited disorder><Intervention><Intrauterine Diagnosis><Kidney><Kidney Diseases><Kidney Urinary System><Laboratories><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Managed Care><Marrow erythrocyte><Medical center><Medication><Morbidity><Morbidity - disease rate><Neonatal Screening><Nephropathy><Neurologic><Neurological><Newborn Infant Screening><Nigeria><On-Line Systems><Online Systems><Ontology><Organ><Outcome><Patient Care><Patient Care Delivery><Patients><Penicillins><Pharmaceutical Preparations><Phase><Phenotype><Pneumococcal vaccine><Policies><Prenatal Diagnosis><Prevent infection><Preventative intervention><Prophylactic treatment><Prophylaxis><Prospective cohort><Proteinuria><Protocol><Protocols documentation><QOL><Quality of life><Recommendation><Recurrence><Recurrent><Red Blood Cells><Red Cell><Registries><Renal Disease><Renin-Angiotensin-Aldosterone System><Research><Research Resources><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Resources><Sickle Cell><Sickle Cell Anemia><Sight><Site><Standardization><Streptococcus pneumoniae vaccine><Stroke><Structure><Sub-Saharan Africa><Subsaharan Africa><Syndrome><System><Tanzania><Training><Transfusion><Vascular Endothelium><Vision><Work><adolescence (12-20)><adulthood><antepartum diagnosis><benchmark><blood corpuscles><brain attack><care delivery><care for patients><care of patients><caring for patients><causation><cell registry><cerebral vascular accident><cerebrovascular accident><clinical care><cognitive dysfunction><cognitive loss><cohort><disease causation><drug/agent><electronic><electronic device><enroll><ethical><evidence base><facilitators to implementation><feasibility testing><functional status><genetic condition><genetic disorder><health care policy><hereditary disorder><heritable disorder><hydroxy-urea><hydroxyurea><implementation facilitators><implementation research><implementation strategy><implementation study><improved><inborn error><inherited diseases><inherited genetic disease><inherited genetic disorder><intervention for prevention><intra-uterine diagnosis><juvenile><juvenile human><kidney disorder><kids><life span><lifespan><mHealth therapeutic><mHealth therapy><mHealth treatment><mhealth interventions><mobile health intervention><mobile health therapeutic><mobile health therapy><mobile health treatment><mortality rate><mortality ratio><neuro-vascular><neurovascular><newborn screening><online computer><oxidant stress><pain killer><pain medication><pain reliever><painkiller><patient registry><point of care testing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prophylactic><prospective><recruit><renal><renal disorder><research study><screening><screening program><screenings><sickle RBC><sickle cell disease><sickle cell disorder><sickle disease><sickle erythrocyte><sickle red blood cell><sicklemia><sickling><socio-demographics><sociodemographics><statistics><strategies for implementation><stroked><strokes><systemic inflammation><systemic inflammatory response><visual function><web based><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Fred Stephen Sarfo

KWAME NKRUMAH UNIVERSITY/SCIENCE/TECH, GHANA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$350,302
FY 2025

Project Title

Ghana-SPARCO: Ghana Sickle Pan-African Research Consortium

Grant Number:

5U01HL157004-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/10/2021

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Sickle Cell Disease (SCD) is a recessively inherited disorder characterized by disordered hemoglobin structure, aberrant endothelial interactions, systemic inflammation, oxidant stress, and activation of the coagulation system. These abnormalities underlie a myriad of complications i...

Research Terms

<0-11 years old><12-20 years old><21+ years old><Abnormal Hemoglobins><Acute><Address><Adolescence><Adolescent><Adolescent Youth><Adoption><Adult><Adult Human><Advocacy><Affect><Africa><Africa South of the Sahara><African><Agreement><Analgesic Agents><Analgesic Drugs><Analgesic Preparation><Analgesics><Anodynes><Antenatal Diagnosis><Antinociceptive Agents><Antinociceptive Drugs><Apoplexy><Area><Benchmarking><Best Practice Analysis><Blood Transfusion><Blood erythrocyte><Brain Vascular Accident><Capital><Caring><Causality><Cephalic><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Child><Child Youth><Children (0-21)><Chronic><Cities><Clinic><Clinical><Clotting><Coagulation><Coagulation Process><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Cohort Studies><Concurrent Studies><Consent><Country><Cranial><Data><Death><Death Rate><Decision Making><Disease><Disease Management><Disorder><Disorder Management><Disturbance in cognition><Drugs><Electronics><Endothelium><Enrollment><Erythrocytes><Erythrocytic><Ethics><Etiology><Event><Future><Genes><Genetic Diseases><Genotype><Ghana><Goals><Gold Coast><Grant><Guidelines><Harvest><Hb SS disease><HbSS disease><Health Care><Health Policy><Hematology><Hemoglobin><Hemoglobin S Disease><Hemoglobin sickle cell disease><Hemoglobin sickle cell disorder><Hemolytic Anemia><Hereditary Disease><Hospitals><Hydration><Hydration status><Hydroxycarbamid><Hydroxycarbamide><Impaired cognition><Inborn Genetic Diseases><Incidence><Individual><Infection><Infection prevention><Infrastructure><Inherited disorder><Intervention><Intrauterine Diagnosis><Kidney><Kidney Diseases><Kidney Urinary System><Laboratories><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Managed Care><Marrow erythrocyte><Medical center><Medication><Morbidity><Morbidity - disease rate><Neonatal Screening><Nephropathy><Neurologic><Neurological><Newborn Infant Screening><Nigeria><On-Line Systems><Online Systems><Ontology><Organ><Outcome><Patient Care><Patient Care Delivery><Patients><Penicillins><Pharmaceutical Preparations><Phase><Phenotype><Pneumococcal vaccine><Policies><Prenatal Diagnosis><Prevent infection><Preventative intervention><Prophylactic treatment><Prophylaxis><Prospective cohort><Proteinuria><Protocol><Protocols documentation><QOL><Quality of life><Recommendation><Recurrence><Recurrent><Red Blood Cells><Red Cell><Registries><Renal Disease><Renin-Angiotensin-Aldosterone System><Research><Research Resources><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Resources><Sickle Cell><Sickle Cell Anemia><Sight><Site><Standardization><Streptococcus pneumoniae vaccine><Stroke><Structure><Sub-Saharan Africa><Subsaharan Africa><Syndrome><System><Tanzania><Training><Transfusion><Vascular Endothelium><Vision><Work><adolescence (12-20)><adulthood><antepartum diagnosis><benchmark><blood corpuscles><brain attack><care delivery><care for patients><care of patients><caring for patients><causation><cell registry><cerebral vascular accident><cerebrovascular accident><clinical care><cognitive dysfunction><cognitive loss><cohort><disease causation><drug/agent><electronic><electronic device><enroll><ethical><evidence base><facilitators to implementation><feasibility testing><functional status><genetic condition><genetic disorder><health care policy><hereditary disorder><heritable disorder><hydroxy-urea><hydroxyurea><implementation facilitators><implementation research><implementation strategy><implementation study><improved><inborn error><inherited diseases><inherited genetic disease><inherited genetic disorder><intervention for prevention><intra-uterine diagnosis><juvenile><juvenile human><kidney disorder><kids><life span><lifespan><mHealth therapeutic><mHealth therapy><mHealth treatment><mhealth interventions><mobile health intervention><mobile health therapeutic><mobile health therapy><mobile health treatment><mortality rate><mortality ratio><neuro-vascular><neurovascular><newborn screening><online computer><oxidant stress><pain killer><pain medication><pain reliever><painkiller><patient registry><point of care testing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prophylactic><prospective><recruit><renal><renal disorder><research study><screening><screening program><screenings><sickle RBC><sickle cell disease><sickle cell disorder><sickle disease><sickle erythrocyte><sickle red blood cell><sicklemia><sickling><socio-demographics><sociodemographics><statistics><strategies for implementation><stroked><strokes><systemic inflammation><systemic inflammatory response><visual function><web based><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Roberto G Lucchini

FLORIDA INTERNATIONAL UNIVERSITY, MIAMI, FL

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$349,937
FY 2025

Project Title

Clinician-Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida.

Grant Number:

5U01OH012773-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

ALLCDC

Start Date:

7/1/2024

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT The World Trade Center (WTC) General Responders (GRs) carry a significant mental health (MH) burden from the exposure to intense psychological trauma after the WTC collapse. PTSD and depression are two of the top ten certifiable mental health conditions that the 9/11 GRs are...

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARK J MACGOWAN

FLORIDA INTERNATIONAL UNIVERSITY, MIAMI, FL

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$349,937
FY 2025

Project Title

Clinician-Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida.

Grant Number:

5U01OH012773-02

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

ALLCDC

Start Date:

7/1/2024

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT The World Trade Center (WTC) General Responders (GRs) carry a significant mental health (MH) burden from the exposure to intense psychological trauma after the WTC collapse. PTSD and depression are two of the top ten certifiable mental health conditions that the 9/11 GRs are...

View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Martin Cadeiras

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$332,855
FY 2025

Project Title

A prospective multiethnic HFpEF cohort from California's Central Valley

Grant Number:

5U01HL160274-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT This is a new U01 application to establish a Clinical Center (CC) for a prospective multiethnic HFpEF cohort from California central valley for deep phenotyping analyses. The investigative team is diverse, multidisciplinary, and complementary with investigators from School of Medicine, Coll...

Research Terms

<Age><Agriculture><Area><Atrial Fibrillation><Auricular Fibrillation><Blood flow><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Catchment Area><Center for Translational Science Activities><Central Valley><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Classification><Clinic><Clinical><Clinical Research><Clinical Sciences><Clinical Study><Community Hospitals><Complex><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Country><Coupled><Data><Data Science><Data Set><Development><Diabetes Mellitus><Diastolic heart failure><Disease><Disorder><EFRAC><Ejection Fraction><Electronic Health Record><Engineering><Enrollment><Environmental Science><Event><Funding><Generalized Growth><Genomics><Growth><HF with preserved ejection fraction><HFpEF><Health Care Technology><Health Technology><Heart><Heart Vascular><Heart failure><Heterogeneity><Hypertension><Image><Incidence><Inflammation><Inflammatory><Investigators><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Learning><Machine Learning><Metabolic><Metabolic syndrome><Mining><Molecular><Molecular Analysis><Morbidity><Morbidity - disease rate><NIH><National Institutes of Health><Obesity><Organ><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Patients><Phase><Phenotype><Plug-in><Population><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Progressive Disease><Proteomics><Pulmonary Hypertension><QOL><Quality of life><Rad.-PET><Records><Research><Research Institute><Research Personnel><Researchers><Role><Source><Syndrome><Systematics><Testing><Text><Therapeutic><Tissue Growth><United States><United States National Institutes of Health><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adiposity><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging associated disease><aging associated disorders><aging population><aging related disease><aging related disorders><atherosclerotic coronary disease><biomedical referral center><cardiac failure><cardiovascular disorder><career development><chronic kidney disease><circulatory system><clinical center><co-morbid><co-morbidity><cohort><college><collegiate><community clinic><comorbidity><connectome><coronary arterial disease><corpulence><developmental><diabetes><discovery mining><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><diverse populations><electronic data><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><functional status><heart failure and reduced ejection fraction><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart failure with reduced ejection fraction><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><indexing><innovate><innovation><innovative><insight><internet portal><literature mining><literature searching><m-Health><mHealth><machine based learning><medical college><medical schools><metabolism measurement><metabolomics><metabonomics><microbiome><minority communities><mobile health><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mortality><multi-ethnic><multidisciplinary><multiethnic><multiomics><multiple omics><next generation><novel><on-line portal><online portal><ontogeny><panomics><participant engagement><participant enrollment><patient engagement><patient enrollment><patient population><phenomics><phrases><population aging><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><preserved ejection fraction heart failure><programs><prospective><protocol development><recruit><referral center><remote monitoring><school of medicine><sex><skill acquisition><skill development><social role><text mining><text searching><translational research center><translational sciences center><web portal><web-based portal>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nipavan Chiamvimonvat

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$332,855
FY 2025

Project Title

A prospective multiethnic HFpEF cohort from California's Central Valley

Grant Number:

5U01HL160274-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT This is a new U01 application to establish a Clinical Center (CC) for a prospective multiethnic HFpEF cohort from California central valley for deep phenotyping analyses. The investigative team is diverse, multidisciplinary, and complementary with investigators from School of Medicine, Coll...

Research Terms

<Age><Agriculture><Area><Atrial Fibrillation><Auricular Fibrillation><Blood flow><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Catchment Area><Center for Translational Science Activities><Central Valley><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Classification><Clinic><Clinical><Clinical Research><Clinical Sciences><Clinical Study><Community Hospitals><Complex><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Country><Coupled><Data><Data Science><Data Set><Development><Diabetes Mellitus><Diastolic heart failure><Disease><Disorder><EFRAC><Ejection Fraction><Electronic Health Record><Engineering><Enrollment><Environmental Science><Event><Funding><Generalized Growth><Genomics><Growth><HF with preserved ejection fraction><HFpEF><Health Care Technology><Health Technology><Heart><Heart Vascular><Heart failure><Heterogeneity><Hypertension><Image><Incidence><Inflammation><Inflammatory><Investigators><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Learning><Machine Learning><Metabolic><Metabolic syndrome><Mining><Molecular><Molecular Analysis><Morbidity><Morbidity - disease rate><NIH><National Institutes of Health><Obesity><Organ><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Patients><Phase><Phenotype><Plug-in><Population><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Progressive Disease><Proteomics><Pulmonary Hypertension><QOL><Quality of life><Rad.-PET><Records><Research><Research Institute><Research Personnel><Researchers><Role><Source><Syndrome><Systematics><Testing><Text><Therapeutic><Tissue Growth><United States><United States National Institutes of Health><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adiposity><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging associated disease><aging associated disorders><aging population><aging related disease><aging related disorders><atherosclerotic coronary disease><biomedical referral center><cardiac failure><cardiovascular disorder><career development><chronic kidney disease><circulatory system><clinical center><co-morbid><co-morbidity><cohort><college><collegiate><community clinic><comorbidity><connectome><coronary arterial disease><corpulence><developmental><diabetes><discovery mining><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><diverse populations><electronic data><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><functional status><heart failure and reduced ejection fraction><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart failure with reduced ejection fraction><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><indexing><innovate><innovation><innovative><insight><internet portal><literature mining><literature searching><m-Health><mHealth><machine based learning><medical college><medical schools><metabolism measurement><metabolomics><metabonomics><microbiome><minority communities><mobile health><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mortality><multi-ethnic><multidisciplinary><multiethnic><multiomics><multiple omics><next generation><novel><on-line portal><online portal><ontogeny><panomics><participant engagement><participant enrollment><patient engagement><patient enrollment><patient population><phenomics><phrases><population aging><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><preserved ejection fraction heart failure><programs><prospective><protocol development><recruit><referral center><remote monitoring><school of medicine><sex><skill acquisition><skill development><social role><text mining><text searching><translational research center><translational sciences center><web portal><web-based portal>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Javier Enrique Lopez

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$332,855
FY 2025

Project Title

A prospective multiethnic HFpEF cohort from California's Central Valley

Grant Number:

5U01HL160274-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT This is a new U01 application to establish a Clinical Center (CC) for a prospective multiethnic HFpEF cohort from California central valley for deep phenotyping analyses. The investigative team is diverse, multidisciplinary, and complementary with investigators from School of Medicine, Coll...

Research Terms

<Age><Agriculture><Area><Atrial Fibrillation><Auricular Fibrillation><Blood flow><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Catchment Area><Center for Translational Science Activities><Central Valley><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Classification><Clinic><Clinical><Clinical Research><Clinical Sciences><Clinical Study><Community Hospitals><Complex><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Country><Coupled><Data><Data Science><Data Set><Development><Diabetes Mellitus><Diastolic heart failure><Disease><Disorder><EFRAC><Ejection Fraction><Electronic Health Record><Engineering><Enrollment><Environmental Science><Event><Funding><Generalized Growth><Genomics><Growth><HF with preserved ejection fraction><HFpEF><Health Care Technology><Health Technology><Heart><Heart Vascular><Heart failure><Heterogeneity><Hypertension><Image><Incidence><Inflammation><Inflammatory><Investigators><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Learning><Machine Learning><Metabolic><Metabolic syndrome><Mining><Molecular><Molecular Analysis><Morbidity><Morbidity - disease rate><NIH><National Institutes of Health><Obesity><Organ><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Patients><Phase><Phenotype><Plug-in><Population><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Progressive Disease><Proteomics><Pulmonary Hypertension><QOL><Quality of life><Rad.-PET><Records><Research><Research Institute><Research Personnel><Researchers><Role><Source><Syndrome><Systematics><Testing><Text><Therapeutic><Tissue Growth><United States><United States National Institutes of Health><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adiposity><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging associated disease><aging associated disorders><aging population><aging related disease><aging related disorders><atherosclerotic coronary disease><biomedical referral center><cardiac failure><cardiovascular disorder><career development><chronic kidney disease><circulatory system><clinical center><co-morbid><co-morbidity><cohort><college><collegiate><community clinic><comorbidity><connectome><coronary arterial disease><corpulence><developmental><diabetes><discovery mining><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><diverse populations><electronic data><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><functional status><heart failure and reduced ejection fraction><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart failure with reduced ejection fraction><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><indexing><innovate><innovation><innovative><insight><internet portal><literature mining><literature searching><m-Health><mHealth><machine based learning><medical college><medical schools><metabolism measurement><metabolomics><metabonomics><microbiome><minority communities><mobile health><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mortality><multi-ethnic><multidisciplinary><multiethnic><multiomics><multiple omics><next generation><novel><on-line portal><online portal><ontogeny><panomics><participant engagement><participant enrollment><patient engagement><patient enrollment><patient population><phenomics><phrases><population aging><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><preserved ejection fraction heart failure><programs><prospective><protocol development><recruit><referral center><remote monitoring><school of medicine><sex><skill acquisition><skill development><social role><text mining><text searching><translational research center><translational sciences center><web portal><web-based portal>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ADAM L. BOXER

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$331,127
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S2

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bradley F Boeve

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$331,127
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S2

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HOWARD J ROSEN

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$331,127
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S2

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LAWRENCE JOHN APPEL

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$300,391
FY 2025

Project Title

Limited Competition for the Continuation of the Chronic Renal Insufficiency Cohort (CRIC) Hopkins Clinical Center

Grant Number:

5U01DK061022-25

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/28/2001

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY This application is submitted in response to RFA-DK-22-502, “Limited Competition for the Continuation of the Chronic Renal Insufficiency Cohort (CRIC) Clinical Centers (U01),” aka Phase 5 of CRIC, for the Hopkins/University of Maryland (Hopkins/UMB) Clinical Center. Since its incepti...

Research Terms

<21+ years old><Active Follow-up><Adult><Adult Human><Affect><Ancillary Study><Apoplexy><Arrhythmia><Biological><Brain Vascular Accident><Cardiac Arrhythmia><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Chronic Kidney Failure><Chronic Kidney Insufficiency><Chronic Phase><Chronic Renal Disease><Chronic Renal Failure><Chronic Renal Insufficiency><Clinical><Cohort Studies><Collaborations><Communities><Concurrent Studies><Data><Data Collection><Data Coordinating Center><Data Coordination Center><Data Sources><Death><Dialysis><Dialysis procedure><Disease Progression><Eligibility><Eligibility Determination><Enrollment><Ensure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology><Epidemiology Research><Event><Funding><Future><Goals><Grant><Heart Arrhythmias><Heart Vascular><Heterogeneity><Home><Individual><Institution><Investigation><Investigators><Kidney Diseases><Kidney Failure><Kidney Function Tests><Kidney Grafting><Kidney Insufficiency><Kidney Transplantation><Kidney Transplants><Leadership><Link><Maryland><Measurement><Measures><Medical><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Nephropathy><Observation research><Observation study><Observational Study><Observational epidemiology><Observational research><Outcome><Parents><Participant><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Phase><Phenotype><Physiologic><Physiological><Position><Positioning Attribute><Process><Productivity><Progress Reports><Prospective Studies><Prospective cohort><Protocol><Protocol Screening><Protocols documentation><Publications><Renal Disease><Renal Failure><Renal Grafting><Renal Insufficiency><Renal Transplantation><Renal Transplants><Renal function><Research><Research Design><Research Personnel><Research Resources><Researchers><Resources><Risk Factors><Role><Scientific Publication><Source><Stroke><Study Type><Translational Research><Translational Science><Universities><Visit><active followup><adulthood><adverse consequence><adverse outcome><biologic><brain attack><cardiovascular disorder><cerebral vascular accident><cerebrovascular accident><chronic kidney disease><circulatory system><clinical center><cognitive disability><cognitively disabled><cohort><damage to kidney><data integration><depository><design><designing><dialysis therapy><enroll><epidemiologic><epidemiologic investigation><epidemiological><epidemiology study><ethnic diversity><ethnically diverse><follow up><follow-up><followed up><followup><health data><home test><home-based test><homes><innovate><innovation><innovative><kidney damage><kidney disorder><kidney function><kidney tx><novel><parent><participant enrollment><patient enrollment><patient oriented outcomes><phenotypic data><physical disability><physically disabled><physically handicapped><premature><prematurity><programs><racial diversity><racially diverse><recruit><renal damage><renal disorder><repository><response><social><social role><stroked><strokes><study design><success><tool><translation research><translational investigation>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Davaalkham - Dambadarjaa

MONGOLIAN NATIONAL UNIV/MEDICAL SCIENCES, MONGOLIA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/1 - Mongolian Center for Environmental & Occupational Health - Mongolia

Grant Number:

5U01TW012229-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/13/2022

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT In recent decades, Mongolia has experienced major economic and environmental changes, and suffered from severe air pollution. Ulaanbaatar (UB) and Darkhan City (DC) have some of the highest ambient particulate matter (PM) concentrations in the world and frequently suffer epidemics of viral...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Age><Air><Air Pollution><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Anti-viral Response><Attention><Back><Bacterial Infections><Biological Markers><Biometrics><Biometry><Biostatistics><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 affected><COVID-19 consequence><COVID-19 crisis><COVID-19 effect><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 impact><COVID-19 impacted><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Cell Body><Cell Culture Techniques><Cell model><Cells><Cellular model><Cessation of life><Cities><Coal><Communicable Diseases><Data><Death><Diameter><Disease><Disorder><Dorsum><Economics><Environmental Engineering technology><Environmental Health><Environmental Health Science><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology><Epidemiology Research><Epithelium><Exposure to><Faculty><Government><Grippe><Heating><Heavy Metals><High Prevalence><Human><Immune><Immune Markers><Immune response><Immune signaling><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunological><Immunologically><Immunologics><Immunology><Impairment><Incidence><Infection><Infectious Diseases><Infectious Disorder><Inflammatory><Inflammatory Response><Influenza><Institution><Interdisciplinary Research><Interdisciplinary Study><Interferon Type I><Intervention><Investigators><Laboratories><Length><Ligands><Link><Liquid substance><Literature><Long-term trends><Longer-term trends><Longitudinal trends><Lung Inflammation><Lung TB><Lung Tuberculosis><M tuberculosis infection><M. tb infection><M. tuberculosis infection><M.tb infection><M.tuberculosis infection><MTB infection><Measures><Medical><Medicine><Mentors><Minerals><Modern Man><Mongolia><Morbidity><Morbidity - disease rate><Multidisciplinary Collaboration><Multidisciplinary Research><Mycobacterium tuberculosis (MTB) infection><Mycobacterium tuberculosis infection><Nasal><Nasal Passages Nose><Nose><O3><Observation research><Observation study><Observational Study><Observational epidemiology><Observational research><Occupational Health><Osteoporosis><Oxidative Stress><Ozone><PM10><PM2.5><Participant><Particulate><Particulate Matter><Pilot Projects><Pneumonitis><Policies><Pollution><Population><Predisposition><Probabilistic Models><Probability Models><Process><Protocol><Protocols documentation><Public Health><Publishing><Pulmonary Inflammation><Pulmonary TB><Pulmonary Tuberculosis><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Design><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Respiratory Disease><Respiratory Epithelium><Respiratory System Disease><Respiratory System Disorder><Respiratory System, Nose, Nasal Passages><Risk><Risk Factors><Role><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Science><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severities><Source><Statistical Models><Structure of respiratory epithelium><Study Subject><Study Type><Study models><Susceptibility><TB infection><TLR3><TLR3 gene><TLR7><TLR7 gene><Temperature><Testing><Time><Time Series Analysis><Toll-Like Receptor 3><Toll-Like Receptor 7><Toxicology><Traction><Training><Tuberculosis><Universities><Variant><Variation><Viral><Viral Diseases><Viral Respiratory Tract Infection><Virus><Virus Diseases><Visit><Work><active followup><adulthood><ages><air pollution control><airway epithelium><bacteria infection><bacterial disease><bio-markers><biologic marker><biomarker><bone><cell culture><cell cultures><coarse particles><coarse particulate matter><coronavirus disease 2019 consequence><coronavirus disease 2019 crisis><coronavirus disease 2019 effect><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 impact><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 impact><coronavirus disease-19 pandemic><cytokine><design><designing><disseminated TB><disseminated tuberculosis><economic><environmental change><environmental engineering><epidemiologic><epidemiologic investigation><epidemiological><epidemiology study><experience><experiment><experimental research><experimental study><experiments><fine particles><fine particulate matter><flu><fluid><follow up><follow-up><followed up><followup><host response><immune system response><immune-based biomarkers><immunological biomarkers><immunological markers><immunoresponse><improved><infection due to Mycobacterium tuberculosis><insight><interdisciplinary approach><liquid><member><meter><mortality><multidisciplinary approach><non-smoking><nonsmoking><pilot study><pollutant><premature><prematurity><programs><respiratory><respiratory tract epithelium><response><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social role><statistical linear mixed models><statistical linear models><study design><systemic inflammation><systemic inflammatory response><tuberculosis infection><tuberculous spondyloarthropathy><viral epidemic><viral infection><viral respiratory infection><virology><virus infection><virus-induced disease>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gregory Charles Gray

MONGOLIAN NATIONAL UNIV/MEDICAL SCIENCES, MONGOLIA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/1 - Mongolian Center for Environmental & Occupational Health - Mongolia

Grant Number:

5U01TW012229-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/13/2022

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT In recent decades, Mongolia has experienced major economic and environmental changes, and suffered from severe air pollution. Ulaanbaatar (UB) and Darkhan City (DC) have some of the highest ambient particulate matter (PM) concentrations in the world and frequently suffer epidemics of viral...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Age><Air><Air Pollution><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Anti-viral Response><Attention><Back><Bacterial Infections><Biological Markers><Biometrics><Biometry><Biostatistics><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 affected><COVID-19 consequence><COVID-19 crisis><COVID-19 effect><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 impact><COVID-19 impacted><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Cell Body><Cell Culture Techniques><Cell model><Cells><Cellular model><Cessation of life><Cities><Coal><Communicable Diseases><Data><Death><Diameter><Disease><Disorder><Dorsum><Economics><Environmental Engineering technology><Environmental Health><Environmental Health Science><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology><Epidemiology Research><Epithelium><Exposure to><Faculty><Government><Grippe><Heating><Heavy Metals><High Prevalence><Human><Immune><Immune Markers><Immune response><Immune signaling><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunological><Immunologically><Immunologics><Immunology><Impairment><Incidence><Infection><Infectious Diseases><Infectious Disorder><Inflammatory><Inflammatory Response><Influenza><Institution><Interdisciplinary Research><Interdisciplinary Study><Interferon Type I><Intervention><Investigators><Laboratories><Length><Ligands><Link><Liquid substance><Literature><Long-term trends><Longer-term trends><Longitudinal trends><Lung Inflammation><Lung TB><Lung Tuberculosis><M tuberculosis infection><M. tb infection><M. tuberculosis infection><M.tb infection><M.tuberculosis infection><MTB infection><Measures><Medical><Medicine><Mentors><Minerals><Modern Man><Mongolia><Morbidity><Morbidity - disease rate><Multidisciplinary Collaboration><Multidisciplinary Research><Mycobacterium tuberculosis (MTB) infection><Mycobacterium tuberculosis infection><Nasal><Nasal Passages Nose><Nose><O3><Observation research><Observation study><Observational Study><Observational epidemiology><Observational research><Occupational Health><Osteoporosis><Oxidative Stress><Ozone><PM10><PM2.5><Participant><Particulate><Particulate Matter><Pilot Projects><Pneumonitis><Policies><Pollution><Population><Predisposition><Probabilistic Models><Probability Models><Process><Protocol><Protocols documentation><Public Health><Publishing><Pulmonary Inflammation><Pulmonary TB><Pulmonary Tuberculosis><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Design><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Respiratory Disease><Respiratory Epithelium><Respiratory System Disease><Respiratory System Disorder><Respiratory System, Nose, Nasal Passages><Risk><Risk Factors><Role><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Science><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severities><Source><Statistical Models><Structure of respiratory epithelium><Study Subject><Study Type><Study models><Susceptibility><TB infection><TLR3><TLR3 gene><TLR7><TLR7 gene><Temperature><Testing><Time><Time Series Analysis><Toll-Like Receptor 3><Toll-Like Receptor 7><Toxicology><Traction><Training><Tuberculosis><Universities><Variant><Variation><Viral><Viral Diseases><Viral Respiratory Tract Infection><Virus><Virus Diseases><Visit><Work><active followup><adulthood><ages><air pollution control><airway epithelium><bacteria infection><bacterial disease><bio-markers><biologic marker><biomarker><bone><cell culture><cell cultures><coarse particles><coarse particulate matter><coronavirus disease 2019 consequence><coronavirus disease 2019 crisis><coronavirus disease 2019 effect><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 impact><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 impact><coronavirus disease-19 pandemic><cytokine><design><designing><disseminated TB><disseminated tuberculosis><economic><environmental change><environmental engineering><epidemiologic><epidemiologic investigation><epidemiological><epidemiology study><experience><experiment><experimental research><experimental study><experiments><fine particles><fine particulate matter><flu><fluid><follow up><follow-up><followed up><followup><host response><immune system response><immune-based biomarkers><immunological biomarkers><immunological markers><immunoresponse><improved><infection due to Mycobacterium tuberculosis><insight><interdisciplinary approach><liquid><member><meter><mortality><multidisciplinary approach><non-smoking><nonsmoking><pilot study><pollutant><premature><prematurity><programs><respiratory><respiratory tract epithelium><response><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social role><statistical linear mixed models><statistical linear models><study design><systemic inflammation><systemic inflammatory response><tuberculosis infection><tuberculous spondyloarthropathy><viral epidemic><viral infection><viral respiratory infection><virology><virus infection><virus-induced disease>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JUNFENG ZHANG

MONGOLIAN NATIONAL UNIV/MEDICAL SCIENCES, MONGOLIA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/1 - Mongolian Center for Environmental & Occupational Health - Mongolia

Grant Number:

5U01TW012229-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/13/2022

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT In recent decades, Mongolia has experienced major economic and environmental changes, and suffered from severe air pollution. Ulaanbaatar (UB) and Darkhan City (DC) have some of the highest ambient particulate matter (PM) concentrations in the world and frequently suffer epidemics of viral...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Age><Air><Air Pollution><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Anti-viral Response><Attention><Back><Bacterial Infections><Biological Markers><Biometrics><Biometry><Biostatistics><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 affected><COVID-19 consequence><COVID-19 crisis><COVID-19 effect><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 impact><COVID-19 impacted><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Cell Body><Cell Culture Techniques><Cell model><Cells><Cellular model><Cessation of life><Cities><Coal><Communicable Diseases><Data><Death><Diameter><Disease><Disorder><Dorsum><Economics><Environmental Engineering technology><Environmental Health><Environmental Health Science><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology><Epidemiology Research><Epithelium><Exposure to><Faculty><Government><Grippe><Heating><Heavy Metals><High Prevalence><Human><Immune><Immune Markers><Immune response><Immune signaling><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunological><Immunologically><Immunologics><Immunology><Impairment><Incidence><Infection><Infectious Diseases><Infectious Disorder><Inflammatory><Inflammatory Response><Influenza><Institution><Interdisciplinary Research><Interdisciplinary Study><Interferon Type I><Intervention><Investigators><Laboratories><Length><Ligands><Link><Liquid substance><Literature><Long-term trends><Longer-term trends><Longitudinal trends><Lung Inflammation><Lung TB><Lung Tuberculosis><M tuberculosis infection><M. tb infection><M. tuberculosis infection><M.tb infection><M.tuberculosis infection><MTB infection><Measures><Medical><Medicine><Mentors><Minerals><Modern Man><Mongolia><Morbidity><Morbidity - disease rate><Multidisciplinary Collaboration><Multidisciplinary Research><Mycobacterium tuberculosis (MTB) infection><Mycobacterium tuberculosis infection><Nasal><Nasal Passages Nose><Nose><O3><Observation research><Observation study><Observational Study><Observational epidemiology><Observational research><Occupational Health><Osteoporosis><Oxidative Stress><Ozone><PM10><PM2.5><Participant><Particulate><Particulate Matter><Pilot Projects><Pneumonitis><Policies><Pollution><Population><Predisposition><Probabilistic Models><Probability Models><Process><Protocol><Protocols documentation><Public Health><Publishing><Pulmonary Inflammation><Pulmonary TB><Pulmonary Tuberculosis><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Design><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Respiratory Disease><Respiratory Epithelium><Respiratory System Disease><Respiratory System Disorder><Respiratory System, Nose, Nasal Passages><Risk><Risk Factors><Role><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Science><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severities><Source><Statistical Models><Structure of respiratory epithelium><Study Subject><Study Type><Study models><Susceptibility><TB infection><TLR3><TLR3 gene><TLR7><TLR7 gene><Temperature><Testing><Time><Time Series Analysis><Toll-Like Receptor 3><Toll-Like Receptor 7><Toxicology><Traction><Training><Tuberculosis><Universities><Variant><Variation><Viral><Viral Diseases><Viral Respiratory Tract Infection><Virus><Virus Diseases><Visit><Work><active followup><adulthood><ages><air pollution control><airway epithelium><bacteria infection><bacterial disease><bio-markers><biologic marker><biomarker><bone><cell culture><cell cultures><coarse particles><coarse particulate matter><coronavirus disease 2019 consequence><coronavirus disease 2019 crisis><coronavirus disease 2019 effect><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 impact><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 impact><coronavirus disease-19 pandemic><cytokine><design><designing><disseminated TB><disseminated tuberculosis><economic><environmental change><environmental engineering><epidemiologic><epidemiologic investigation><epidemiological><epidemiology study><experience><experiment><experimental research><experimental study><experiments><fine particles><fine particulate matter><flu><fluid><follow up><follow-up><followed up><followup><host response><immune system response><immune-based biomarkers><immunological biomarkers><immunological markers><immunoresponse><improved><infection due to Mycobacterium tuberculosis><insight><interdisciplinary approach><liquid><member><meter><mortality><multidisciplinary approach><non-smoking><nonsmoking><pilot study><pollutant><premature><prematurity><programs><respiratory><respiratory tract epithelium><response><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social role><statistical linear mixed models><statistical linear models><study design><systemic inflammation><systemic inflammatory response><tuberculosis infection><tuberculous spondyloarthropathy><viral epidemic><viral infection><viral respiratory infection><virology><virus infection><virus-induced disease>
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Rima Habib

AMERICAN UNIVERSITY OF BEIRUT, LEBANON

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$289,051
FY 2025

Project Title

1/2 - The Global Environmental and Occupational Health Research and Training Hub for the Middle East and North Africa Region (GEOHealth-MENA) - Lebanon

Grant Number:

5U01TW012236-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<0-11 years old><Age><Agricultural Workers><Agriculture><American><Biological><Characteristics><Child><Child Youth><Children (0-21)><Chlorpyrifos><Collaborations><Communities><Conflict><Conflict (Psychology)><Country><Deposit><Deposition><Diet><Disparity population><Doctor of Philosophy><Dose><Economics><Educational workshop><Egypt><Environmental Exposure><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Failure><Fellowship><Female><Goals><Groups at risk><Health><Health Care Professional><Health Professional><Health Sciences><Individual><Industrial Medicine><Ingestion><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lead><Lebanon><Measures><Medicine><Methods><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational><Occupational Exposure><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Organophosphates><Outcome><Pathway interactions><Pb element><People at risk><Performance><Persons at risk><Pesticide Residues><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Populations at Risk><Practice Guidelines><Qualifying><R-Series Research Projects><R01 Mechanism><R01 Program><Refugees><Regulation><Research><Research Grants><Research Project Grants><Research Projects><Research Training><Risk><Role><Route><Safety><Scholarship><Seasons><Sister><Sudan><Syria><Syrian><Syrian Arab Republic><Time><Training><Translating><Universities><Vulnerable Populations><Woman><Work><Workshop><ages><agriculture worker><biologic><cohort><cost><cypermethrin><decamethrin><deltamethrin><diets><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><economic><epidemiologic><epidemiological><exposure route><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><heavy metal Pb><heavy metal lead><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><ingest><involuntary migration><kids><low and middle-income countries><male><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><pyrethroid><recruit><response><sex><social factors><social role><social stresses><social stressor><socio-economic><socio-economically><socioeconomically><socioeconomics><subgroup disparity><supercypermethrin><supermethrin><tool><unequal group><unequal population><urinary><vulnerable group><vulnerable individual><vulnerable people><wearable><wearable device><wearable electronics><wearable system><wearable technology><wearable tool><wearables><workplace exposure><wristband><youngster><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Hani Mowafi

AMERICAN UNIVERSITY OF BEIRUT, LEBANON

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$289,051
FY 2025

Project Title

1/2 - The Global Environmental and Occupational Health Research and Training Hub for the Middle East and North Africa Region (GEOHealth-MENA) - Lebanon

Grant Number:

5U01TW012236-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<0-11 years old><Age><Agricultural Workers><Agriculture><American><Biological><Characteristics><Child><Child Youth><Children (0-21)><Chlorpyrifos><Collaborations><Communities><Conflict><Conflict (Psychology)><Country><Deposit><Deposition><Diet><Disparity population><Doctor of Philosophy><Dose><Economics><Educational workshop><Egypt><Environmental Exposure><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Failure><Fellowship><Female><Goals><Groups at risk><Health><Health Care Professional><Health Professional><Health Sciences><Individual><Industrial Medicine><Ingestion><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lead><Lebanon><Measures><Medicine><Methods><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational><Occupational Exposure><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Organophosphates><Outcome><Pathway interactions><Pb element><People at risk><Performance><Persons at risk><Pesticide Residues><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Populations at Risk><Practice Guidelines><Qualifying><R-Series Research Projects><R01 Mechanism><R01 Program><Refugees><Regulation><Research><Research Grants><Research Project Grants><Research Projects><Research Training><Risk><Role><Route><Safety><Scholarship><Seasons><Sister><Sudan><Syria><Syrian><Syrian Arab Republic><Time><Training><Translating><Universities><Vulnerable Populations><Woman><Work><Workshop><ages><agriculture worker><biologic><cohort><cost><cypermethrin><decamethrin><deltamethrin><diets><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><economic><epidemiologic><epidemiological><exposure route><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><heavy metal Pb><heavy metal lead><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><ingest><involuntary migration><kids><low and middle-income countries><male><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><pyrethroid><recruit><response><sex><social factors><social role><social stresses><social stressor><socio-economic><socio-economically><socioeconomically><socioeconomics><subgroup disparity><supercypermethrin><supermethrin><tool><unequal group><unequal population><urinary><vulnerable group><vulnerable individual><vulnerable people><wearable><wearable device><wearable electronics><wearable system><wearable technology><wearable tool><wearables><workplace exposure><wristband><youngster><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

IMAN A NUWAYHID

AMERICAN UNIVERSITY OF BEIRUT, LEBANON

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$289,051
FY 2025

Project Title

1/2 - The Global Environmental and Occupational Health Research and Training Hub for the Middle East and North Africa Region (GEOHealth-MENA) - Lebanon

Grant Number:

5U01TW012236-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<0-11 years old><Age><Agricultural Workers><Agriculture><American><Biological><Characteristics><Child><Child Youth><Children (0-21)><Chlorpyrifos><Collaborations><Communities><Conflict><Conflict (Psychology)><Country><Deposit><Deposition><Diet><Disparity population><Doctor of Philosophy><Dose><Economics><Educational workshop><Egypt><Environmental Exposure><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Failure><Fellowship><Female><Goals><Groups at risk><Health><Health Care Professional><Health Professional><Health Sciences><Individual><Industrial Medicine><Ingestion><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lead><Lebanon><Measures><Medicine><Methods><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational><Occupational Exposure><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Organophosphates><Outcome><Pathway interactions><Pb element><People at risk><Performance><Persons at risk><Pesticide Residues><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Populations at Risk><Practice Guidelines><Qualifying><R-Series Research Projects><R01 Mechanism><R01 Program><Refugees><Regulation><Research><Research Grants><Research Project Grants><Research Projects><Research Training><Risk><Role><Route><Safety><Scholarship><Seasons><Sister><Sudan><Syria><Syrian><Syrian Arab Republic><Time><Training><Translating><Universities><Vulnerable Populations><Woman><Work><Workshop><ages><agriculture worker><biologic><cohort><cost><cypermethrin><decamethrin><deltamethrin><diets><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><economic><epidemiologic><epidemiological><exposure route><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><heavy metal Pb><heavy metal lead><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><ingest><involuntary migration><kids><low and middle-income countries><male><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><pyrethroid><recruit><response><sex><social factors><social role><social stresses><social stressor><socio-economic><socio-economically><socioeconomically><socioeconomics><subgroup disparity><supercypermethrin><supermethrin><tool><unequal group><unequal population><urinary><vulnerable group><vulnerable individual><vulnerable people><wearable><wearable device><wearable electronics><wearable system><wearable technology><wearable tool><wearables><workplace exposure><wristband><youngster><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CARRIE A REDLICH

AMERICAN UNIVERSITY OF BEIRUT, LEBANON

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$289,051
FY 2025

Project Title

1/2 - The Global Environmental and Occupational Health Research and Training Hub for the Middle East and North Africa Region (GEOHealth-MENA) - Lebanon

Grant Number:

5U01TW012236-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<0-11 years old><Age><Agricultural Workers><Agriculture><American><Biological><Characteristics><Child><Child Youth><Children (0-21)><Chlorpyrifos><Collaborations><Communities><Conflict><Conflict (Psychology)><Country><Deposit><Deposition><Diet><Disparity population><Doctor of Philosophy><Dose><Economics><Educational workshop><Egypt><Environmental Exposure><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Failure><Fellowship><Female><Goals><Groups at risk><Health><Health Care Professional><Health Professional><Health Sciences><Individual><Industrial Medicine><Ingestion><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lead><Lebanon><Measures><Medicine><Methods><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational><Occupational Exposure><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Organophosphates><Outcome><Pathway interactions><Pb element><People at risk><Performance><Persons at risk><Pesticide Residues><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Populations at Risk><Practice Guidelines><Qualifying><R-Series Research Projects><R01 Mechanism><R01 Program><Refugees><Regulation><Research><Research Grants><Research Project Grants><Research Projects><Research Training><Risk><Role><Route><Safety><Scholarship><Seasons><Sister><Sudan><Syria><Syrian><Syrian Arab Republic><Time><Training><Translating><Universities><Vulnerable Populations><Woman><Work><Workshop><ages><agriculture worker><biologic><cohort><cost><cypermethrin><decamethrin><deltamethrin><diets><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><economic><epidemiologic><epidemiological><exposure route><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><heavy metal Pb><heavy metal lead><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><ingest><involuntary migration><kids><low and middle-income countries><male><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><pyrethroid><recruit><response><sex><social factors><social role><social stresses><social stressor><socio-economic><socio-economically><socioeconomically><socioeconomics><subgroup disparity><supercypermethrin><supermethrin><tool><unequal group><unequal population><urinary><vulnerable group><vulnerable individual><vulnerable people><wearable><wearable device><wearable electronics><wearable system><wearable technology><wearable tool><wearables><workplace exposure><wristband><youngster><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DEBBIE L COHEN

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$280,261
FY 2025

Project Title

Prospective renal insufficiency cohort evaluation: PRICE

Grant Number:

5U01DK060984-25

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/28/2001

End Date:

12/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY This application is submitted in response to RFA-DK-22-502, “Limited Competition: Continuation of the Chronic Renal Insufficiency Cohort (CRIC) Study (U01)” on behalf of the University of Pennsylvania (Penn) Clinical Center. Chronic kidney disease (CKD) affects over 37 million Americ...

Research Terms

<21+ years old><Active Follow-up><Adult><Adult Human><Affect><American><Ancillary Study><Arrhythmia><Biological><Cardiac Arrhythmia><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Manifestation><Cardiovascular Organ System><Cardiovascular system><Chronic Kidney Failure><Chronic Kidney Insufficiency><Chronic Phase><Chronic Renal Disease><Chronic Renal Failure><Chronic Renal Insufficiency><Clinical><Clinical Research><Clinical Study><Cohort Studies><Collaborations><Communities><Concurrent Studies><Data><Data Collection><Data Coordinating Center><Data Coordination Center><Data Sources><Development><Disease><Disease Progression><Disorder><ESKD><ESRD><Eligibility><Eligibility Determination><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Enrollment><Ensure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology><Epidemiology Research><Evaluation><Event><Evolution><Funding><Future><Goals><Heart Arrhythmias><Heart Vascular><Heterogeneity><Home><Individual><Institution><Investigation><Investigators><Kidney Diseases><Kidney Failure><Kidney Function Tests><Kidney Insufficiency><Laboratory Research><Link><Measurement><Measures><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Nephropathy><Observational epidemiology><Outcome><Output><Parents><Participant><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Pennsylvania><Phase><Phenotype><Physiologic><Physiological><Premature Mortality><Process><Productivity><Prospective Studies><Prospective cohort><Prospective, cohort study><Protocol><Protocol Screening><Protocols documentation><Renal Disease><Renal Failure><Renal Insufficiency><Renal function><Research><Research Personnel><Research Resources><Researchers><Resources><Risk Factors><Site><Source><Translational Research><Translational Science><Universities><Visit><active followup><adulthood><biologic><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><care costs><chronic kidney disease><circulatory system><clinical center><co-morbid><co-morbidity><cohort><comorbidity><damage to kidney><data integration><depository><design><designing><developmental><disability><disease risk><disorder risk><enroll><epidemiologic><epidemiologic investigation><epidemiological><epidemiology study><ethnic diversity><ethnically diverse><follow up><follow-up><followed up><followup><health data><home test><home-based test><homes><innovate><innovation><innovative><kidney damage><kidney development><kidney disorder><kidney function><nephrogenesis><novel><parent><participant enrollment><pathway><patient enrollment><patient oriented outcomes><phenotypic data><programs><progression risk><prospective><racial diversity><racially diverse><recruit><renal damage><renal disorder><repository><response><social><tool><translation research><translational investigation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

GREGORY M SULLIVAN

TONIX PHARMACEUTICALS, INC., Chatham, NJ

Good lead · 52/100
Likely hiring
Above-average budget
Team-scale grant
$605,767
FY 2025

Project Title

Development of TNX-1300 (Double Mutant Cocaine Esterase) for the Treatment of Life-Threatening Cocaine Intoxication

Grant Number:

5U01DA056245-03

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2022

End Date:

11/30/2025

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT In the United States, recreational cocaine use continues to represent a significant public health concern. In 2018, an estimated 5.5 million people recreationally self-administered cocaine by insufflation, inhalation, or injection. Many of these individuals are at risk of su...

Research Terms

<Accident and Emergency department><Acute><Address><Applications Grants><Assay><Behavioral Symptoms><Bioassay><Biological Assay><Blood><Blood Plasma><Blood Reticuloendothelial System><Butyrylcholinesterase><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Circulation><Clinical><Clinical Research><Clinical Study><Cocaine><Cocaine Abuse><Coupled><Development><Diagnosis><Dose><Drug Therapy><Drugs><ED care><ER care><Emergency Care><Emergency Department><Emergency Department care><Emergency Room care><Emergency health care><Emergency medical care><Emergency room><Enzyme Gene><Enzymes><Fermentation><Food and Drug Administration><Freeze Drying><Freeze Dryings><Future><Goals><Grant Proposals><Health><Health Care Facility><Health Facilities><Heart Vascular><IND Filing><IND application><IND package><IND submission><Individual><Inhalation><Inhaling><Injections><Insufflation><Intervention><Intoxication><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Laboratory Study><Life><Lyophilization><Market Research><Marketing><Measures><Medical><Medication><Nature><Neurologic><Neurologic Manifestations><Neurologic Signs and Symptoms><Neurologic Symptoms><Neurological><Neurological Manifestations><Neurological Signs and Symptoms><Outcome><Output><Patients><Persons><Pharmaceutical Agent><Pharmaceutical Preparations><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Pharmacological Treatment><Pharmacotherapy><Phase><Phase III study><Physicians><Plasma><Plasma Serum><Position><Positioning Attribute><Preparation><Prevalence><Process><Production><Program Development><Public Health><Publications><Randomization trial><Recombinants><Recreation><Reticuloendothelial System, Serum, Plasma><Risk><Running><Safety><Scientific Publication><Serious Adverse Event><Severe Adverse Event><Single-Blind Study><Single-blind><Site><Supportive Therapy><Supportive care><Symptoms><Temperature><Testing><Therapeutic><Therapeutic Agents><Toxic effect><Toxicities><USFDA><United States><United States Food and Drug Administration><acute care><associated symptom><benzoylecgonine ethyl ester><care facilities><circulatory system><co-morbid symptom><co-occuring symptom><coca-ethylene><cocaethylene><cocaine carboxylesterase><cocaine esterase><cocaine self-administration><cocaine use><commercialization><comorbid symptom><concurrent symptom><cooccuring symptom><cost><design><designing><determine efficacy><developmental><drug intervention><drug treatment><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><emergency settings><ethylcocaine><evaluate efficacy><examine efficacy><experience><first in man><first-in-human><healthy volunteer><human study><individual patient><innovate><innovation><innovative><insight><intravenous administration><intravenous injection><manufacturing process><meeting><meetings><mutant><neural manifestation><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><norcocaine><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><open label><open label study><pharmaceutical><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><phase 2 study><phase 3 study><phase II study><preparations><programs><randomized trial><self-administer cocaine><serious adverse experience><serious adverse reaction><standard of care><symptom association><symptom comorbidity><thermolability><thermostability>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Robert Wilson Frenck

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 50/100
Training-friendly
Solid budget
Recent
Active award
$297,400
FY 2026

Project Title

Vaccinology Training Program

Grant Number:

5T32AI165396-05

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

2/9/2022

End Date:

1/31/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

This is a new application for a T32 training program that will train the next generation of leaders in vaccine science. The Vaccinology Training Program (VTP) builds on a strong legacy of vaccine development at Cincinnati Children’s Hospital and the University of Cincinnati that includes the oral po...

Research Terms

<Training Programs><vaccinology>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PAUL W. SPEARMAN

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 50/100
Training-friendly
Solid budget
Recent
Active award
$297,400
FY 2026

Project Title

Vaccinology Training Program

Grant Number:

5T32AI165396-05

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

2/9/2022

End Date:

1/31/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

This is a new application for a T32 training program that will train the next generation of leaders in vaccine science. The Vaccinology Training Program (VTP) builds on a strong legacy of vaccine development at Cincinnati Children’s Hospital and the University of Cincinnati that includes the oral po...

Research Terms

<Training Programs><vaccinology>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sing Sing Way

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 50/100
Training-friendly
Solid budget
Recent
Active award
$297,400
FY 2026

Project Title

Vaccinology Training Program

Grant Number:

5T32AI165396-05

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

2/9/2022

End Date:

1/31/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

This is a new application for a T32 training program that will train the next generation of leaders in vaccine science. The Vaccinology Training Program (VTP) builds on a strong legacy of vaccine development at Cincinnati Children’s Hospital and the University of Cincinnati that includes the oral po...

Research Terms

<Training Programs><vaccinology>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

NINA S KADAN-LOTTICK

SEATTLE CHILDREN'S HOSPITAL, SEATTLE, WA

Good lead · 46/100
Likely hiring
Solid budget
Active award
$395,889
FY 2025

Project Title

Developing and Testing a Culturally Tailored Mobile Health and Social MediaPhysical Activity Intervention Among Adolescent and Young Adult ChildhoodCancer Survivors

Grant Number:

5R01CA274450-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/21/2023

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Childhood cancer survivors with Spanish ancestry, customs, and/or traditions (henceforth termed ancestry) have an increased risk of cardiometabolic dysfunction. While physical activity (PA) is associated with lower risk of cancer recurrence, cardiometabolic dysfunction, and higher quality of life, 5...

Research Terms

<Accelerometer><Adolescent and Young Adult><Adverse Late Effects><Age><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Cancer Control><Cancer Control Science><Cancer Treatment><Cancers><Cardiac Chronotropism><Cardiomyopathies><Cardiopulmonary><Children's Oncology Group><Chronic><Communication><Conditioning Therapy><Control Groups><Custom><Diet and Nutrition><Dysfunction><Dyslipidemias><Enrollment><Espanol><Evaluation><Fatigue><Feedback><Functional disorder><Funding><Future><General Population><General Public><Goals><Guidelines><Health><Health behavior><Heart Rate><Infrastructure><Instagram><Insulin Resistance><Intervention><Intervention Studies><Interview><Lack of Energy><Language><Late Effects><Maintenance><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Modeling><Modification><Myocardial Diseases><Myocardial Disorder><Myocardiopathies><Obesity><Outcome><Participant><Patient Recruitments><Patient Self-Report><Patients><Pediatric Oncology Group><Phase><Physical Function><Physical activity><Physiopathology><Population Intervention><Population Sciences><Preparation><Privatization><Process><QOL><Quality of life><Randomized><Randomized, Controlled Trials><Recommendation><Recurrent Malignant Neoplasm><Recurrent Malignant Tumor><Reporting><Research><Rest><Risk><Self-Help Groups><Self-Report><Site><Social Functioning><Spanish><Step Tests><Support Groups><Survivors><Target Populations><Test Result><Testing><Time><Treatment Efficacy><accelerometry><activity monitor><activity tracker><adiposity><adult youth><ages><anti-cancer therapy><arm><behavior intervention><behavioral intervention><cancer complication><cancer recurrence><cancer risk><cancer therapy><cancer-directed therapy><cardiometabolic><cardiometabolic risk><cardiometabolism><cardiovascular health><childhood cancer survivor><corpulence><curative intervention><curative therapeutic><curative therapy><curative treatments><customs><design><designing><develop therapy><efficacy testing><enroll><exercise intervention><fitbit><fitness><function socially><functioning social><health related behavior><health related quality of life><heart rate monitor><improved><innovate><innovation><innovative><instrument><insulin resistant><insulin tolerance><intervention design><intervention development><intervention efficacy><intervention participants><intervention research><interventional research><interventional study><interventions research><m-Health><mHealth><malignancy><mobile health><moderate-to-vigorous physical activity><myocardium disease><myocardium disorder><neoplasm/cancer><novel><participant enrollment><participant recruitment><pathophysiology><patient enrollment><pediatric cancer survivor><peer support><physical activity intervention><population based intervention><population specific intervention><portability><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><preference><preparations><prevent><preventing><primary outcome><randomisation><randomization><randomized control trial><randomly assigned><recruit><response><sedentary><self help organization><social><social media><systematic review><therapeutic efficacy><therapy design><therapy development><therapy efficacy><treatment design><treatment development><virtual><young adult><young adult age><young adulthood>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jason A Mendoza

SEATTLE CHILDREN'S HOSPITAL, SEATTLE, WA

Good lead · 46/100
Likely hiring
Solid budget
Active award
$395,889
FY 2025

Project Title

Developing and Testing a Culturally Tailored Mobile Health and Social MediaPhysical Activity Intervention Among Adolescent and Young Adult ChildhoodCancer Survivors

Grant Number:

5R01CA274450-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/21/2023

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Childhood cancer survivors with Spanish ancestry, customs, and/or traditions (henceforth termed ancestry) have an increased risk of cardiometabolic dysfunction. While physical activity (PA) is associated with lower risk of cancer recurrence, cardiometabolic dysfunction, and higher quality of life, 5...

Research Terms

<Accelerometer><Adolescent and Young Adult><Adverse Late Effects><Age><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Cancer Control><Cancer Control Science><Cancer Treatment><Cancers><Cardiac Chronotropism><Cardiomyopathies><Cardiopulmonary><Children's Oncology Group><Chronic><Communication><Conditioning Therapy><Control Groups><Custom><Diet and Nutrition><Dysfunction><Dyslipidemias><Enrollment><Espanol><Evaluation><Fatigue><Feedback><Functional disorder><Funding><Future><General Population><General Public><Goals><Guidelines><Health><Health behavior><Heart Rate><Infrastructure><Instagram><Insulin Resistance><Intervention><Intervention Studies><Interview><Lack of Energy><Language><Late Effects><Maintenance><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Modeling><Modification><Myocardial Diseases><Myocardial Disorder><Myocardiopathies><Obesity><Outcome><Participant><Patient Recruitments><Patient Self-Report><Patients><Pediatric Oncology Group><Phase><Physical Function><Physical activity><Physiopathology><Population Intervention><Population Sciences><Preparation><Privatization><Process><QOL><Quality of life><Randomized><Randomized, Controlled Trials><Recommendation><Recurrent Malignant Neoplasm><Recurrent Malignant Tumor><Reporting><Research><Rest><Risk><Self-Help Groups><Self-Report><Site><Social Functioning><Spanish><Step Tests><Support Groups><Survivors><Target Populations><Test Result><Testing><Time><Treatment Efficacy><accelerometry><activity monitor><activity tracker><adiposity><adult youth><ages><anti-cancer therapy><arm><behavior intervention><behavioral intervention><cancer complication><cancer recurrence><cancer risk><cancer therapy><cancer-directed therapy><cardiometabolic><cardiometabolic risk><cardiometabolism><cardiovascular health><childhood cancer survivor><corpulence><curative intervention><curative therapeutic><curative therapy><curative treatments><customs><design><designing><develop therapy><efficacy testing><enroll><exercise intervention><fitbit><fitness><function socially><functioning social><health related behavior><health related quality of life><heart rate monitor><improved><innovate><innovation><innovative><instrument><insulin resistant><insulin tolerance><intervention design><intervention development><intervention efficacy><intervention participants><intervention research><interventional research><interventional study><interventions research><m-Health><mHealth><malignancy><mobile health><moderate-to-vigorous physical activity><myocardium disease><myocardium disorder><neoplasm/cancer><novel><participant enrollment><participant recruitment><pathophysiology><patient enrollment><pediatric cancer survivor><peer support><physical activity intervention><population based intervention><population specific intervention><portability><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><preference><preparations><prevent><preventing><primary outcome><randomisation><randomization><randomized control trial><randomly assigned><recruit><response><sedentary><self help organization><social><social media><systematic review><therapeutic efficacy><therapy design><therapy development><therapy efficacy><treatment design><treatment development><virtual><young adult><young adult age><young adulthood>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Anupriya Agarwal

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Solid budget
Team-scale grant
$497,412
FY 2025

Project Title

The role of inflammation in driving leukemogenesis in germline predisposition syndromes

Grant Number:

5U01CA257666-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2022

End Date:

4/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Germline predisposition to hematopoietic malignancies (HMs) is more common than previously appreciated, but individuals are spread throughout the country, with few local experts. The NIH provides focused clinics for patients with germline GATA2 mutations under Drs. Holland and Hickst...

Research Terms

<AML1><AMLCR1><Acceleration><Acute T Cell Leukemia><Acute T-Cell Lymphoblastic Leukemia><Acute T-Cell Lymphocytic Leukemia><Acute T-Lymphocytic Leukemia><Adolescent><Adolescent Youth><Age><Assay><Automobile Driving><B blood cells><B cell><B cell malignancy><B cells><B lymphoid malignancy><B-Cells><B-Lymphocytes><B-cell><Basal Transcription Factor><Basal transcription factor genes><Benchmarking><Benign><Best Practice Analysis><Bioassay><Biological Assay><Blood Platelets><Blood Precursor Cell><Blood monocyte><Bone marrow failure><CBFA2><Cancers><Cell Body><Cell Communication and Signaling><Cell Differentiation><Cell Differentiation process><Cell Line><Cell Signaling><CellLine><Cells><Cellular Expansion><Cellular Growth><Characteristics><Chemotactic Cytokines><Chicago><Classification><Clinic><Clinical Evaluation><Clinical Testing><Clinical Trials><Clinical assessments><Clonal Expansion><Clonal expansion of hematopoietic cells><Clonal expansion of hematopoietic stem cells><Clonal hematopoietic expansion><Collection><Country><Cytotoxic cell><DNA mutation><Data><Defect><Dendritic Cells><Development><Differentiation and Growth><Disease><Disorder><Drug usage><Dysmyelopoietic Syndromes><EXTMR><Emberger syndrome><Extramural><Extramural Activities><Family><Fungus Diseases><GATA2 deficiency><GATA2 haploinsufficiency><Gene Alteration><Gene Mutation><General Population><General Public><General Transcription Factor Gene><General Transcription Factors><Generalized Growth><Genetic Change><Genetic defect><Genetic mutation><Germ Lines><Growth><HSC expansion><Health><Hematopoietic><Hematopoietic Cell Tumor><Hematopoietic Malignancies><Hematopoietic Neoplasms><Hematopoietic Neoplasms including Lymphomas><Hematopoietic Progenitor Cells><Hematopoietic Tumor><Hematopoietic and Lymphoid Cell Neoplasm><Hematopoietic and Lymphoid Neoplasms><Hematopoietic stem cells><Hereditary><Heterograft><Heterologous Transplantation><Homolog of Drosophila TOLL><Homologous Chemotactic Cytokines><Immune><Immunes><In Vitro><Individual><Infection><Inflammation><Inflammatory><Inflammatory Response><Inherited><Intercrines><Intracellular Communication and Signaling><Investigators><K lymphocyte><Laboratories><Ligands><Long-term infection><Malignant Hematopoietic Neoplasm><Malignant Neoplasms><Malignant Tumor><Marrow monocyte><Marrow platelet><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Mice><Mice Mammals><MonoMAC><Monosomy 7><Murine><Mus><Mutation><Mycoses><Myelodysplastic Disease><Myelodysplastic Syndromes><Myeloid Disease><Myeloid Malignancy><Myeloid Neoplasm><Myeloid Tumor><Myeloproliferative Disorders><Myeloproliferative Tumors><Myeloproliferative disease><NIH><NK Cells><National Institutes of Health><Natural Killer Cells><Oregon><PEBP2A2><PEBP2aB><Pathogenicity><Pathway interactions><Patients><Pennsylvania><Platelets><Pre-Clinical Model><Preclinical Models><Precursor T Lymphoblastic Leukemia><Predisposition><RUNX1><RUNX1 gene><Refractory Anemia with an Excess of Blasts><Refractory anaemia with excess blasts><Research Personnel><Researchers><Risk><Role><SIS cytokines><Sampling><Science><Signal Transduction><Signal Transduction Systems><Signaling><Smoldering Leukemia><Somatic Mutation><Source><Strains Cell Lines><Stromal Cells><Susceptibility><Syndrome><Systematics><T-Cell Type Acute Leukemia><T-lineage acute lymphoblastic leukemia><TLR4><TLR4 gene><Testing><Thrombocytes><Tissue Growth><Toll Homologue><Transcription Factor Proto-Oncogene><Transcription factor genes><Translational Research><Translational Science><United States National Institutes of Health><Universities><Variant><Variation><Veiled Cells><Viral><Wisconsin><Work><Xenograft><Xenograft procedure><Xenotransplantation><acute infection><ages><benchmark><biological signal transduction><biomarker identification><blood cancer><blood cell progenitor><blood progenitor><blood progenitor cell expansion><blood progenitor expansion><blood stem cell><blood stem cell expansion><blood-forming stem cell><cancer of blood><cancer of the blood><cell growth><cellular differentiation><chemoattractant cytokine><chemokine><chronic infection><clinical center><clinical test><clonal expansions in the blood><clonal hematopoiesis><clones in hematopoietic cells><cultured cell line><cytokine><derepression><design><designing><developmental><driver lesion><driver mutation><driving><drug use><fungal infection><fungus infection><gene defect><genome mutation><hematopoietic cell clones><hematopoietic progenitor><hematopoietic progenitor cell expansion><hematopoietic progenitor expansion><hematopoietic stem cell clonality><hematopoietic stem cell expansion><hematopoietic stem progenitor cell><hemopoietic><hemopoietic progenitor><hemopoietic stem cell><high risk><hypoimmunity><identification of biomarkers><identification of new biomarkers><immune deficiency><immunodeficiency><improved><inflammatory environment><inflammatory milieu><innovate><innovation><innovative><interest><juvenile><juvenile human><leukemia><leukemogenesis><malignancy><marker identification><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><monocyte><mouse model><murine model><mutant><mutant allele><mutation carrier><myelodysplasia><myeloproliferative neoplasm><neoplasm/cancer><new approaches><non-tuberculosis mycobacteria><non-tuberculosis mycobacterial><non-tuberculous mycobacteria><non-tuberculous mycobacterial><nontuberculosis mycobacterial><nontuberculous mycobacteria><nontuberculous mycobacterial><novel approaches><novel strategies><novel strategy><ontogeny><pathway><persistent infection><prevent><preventing><progenitor Cell growth><progenitor growth><programs><research clinical testing><response><social role><somatic variant><stem cell growth><systemic inflammation><systemic inflammatory response><toll-like receptor 4><transcription factor><translation research><translational investigation><unclassified variant><variant of uncertain clinical significance><variant of uncertain significance><variant of undetermined significance><variant of unknown significance><xeno-transplant><xeno-transplantation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Emery H. Bresnick

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Solid budget
Team-scale grant
$497,412
FY 2025

Project Title

The role of inflammation in driving leukemogenesis in germline predisposition syndromes

Grant Number:

5U01CA257666-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2022

End Date:

4/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Germline predisposition to hematopoietic malignancies (HMs) is more common than previously appreciated, but individuals are spread throughout the country, with few local experts. The NIH provides focused clinics for patients with germline GATA2 mutations under Drs. Holland and Hickst...

Research Terms

<AML1><AMLCR1><Acceleration><Acute T Cell Leukemia><Acute T-Cell Lymphoblastic Leukemia><Acute T-Cell Lymphocytic Leukemia><Acute T-Lymphocytic Leukemia><Adolescent><Adolescent Youth><Age><Assay><Automobile Driving><B blood cells><B cell><B cell malignancy><B cells><B lymphoid malignancy><B-Cells><B-Lymphocytes><B-cell><Basal Transcription Factor><Basal transcription factor genes><Benchmarking><Benign><Best Practice Analysis><Bioassay><Biological Assay><Blood Platelets><Blood Precursor Cell><Blood monocyte><Bone marrow failure><CBFA2><Cancers><Cell Body><Cell Communication and Signaling><Cell Differentiation><Cell Differentiation process><Cell Line><Cell Signaling><CellLine><Cells><Cellular Expansion><Cellular Growth><Characteristics><Chemotactic Cytokines><Chicago><Classification><Clinic><Clinical Evaluation><Clinical Testing><Clinical Trials><Clinical assessments><Clonal Expansion><Clonal expansion of hematopoietic cells><Clonal expansion of hematopoietic stem cells><Clonal hematopoietic expansion><Collection><Country><Cytotoxic cell><DNA mutation><Data><Defect><Dendritic Cells><Development><Differentiation and Growth><Disease><Disorder><Drug usage><Dysmyelopoietic Syndromes><EXTMR><Emberger syndrome><Extramural><Extramural Activities><Family><Fungus Diseases><GATA2 deficiency><GATA2 haploinsufficiency><Gene Alteration><Gene Mutation><General Population><General Public><General Transcription Factor Gene><General Transcription Factors><Generalized Growth><Genetic Change><Genetic defect><Genetic mutation><Germ Lines><Growth><HSC expansion><Health><Hematopoietic><Hematopoietic Cell Tumor><Hematopoietic Malignancies><Hematopoietic Neoplasms><Hematopoietic Neoplasms including Lymphomas><Hematopoietic Progenitor Cells><Hematopoietic Tumor><Hematopoietic and Lymphoid Cell Neoplasm><Hematopoietic and Lymphoid Neoplasms><Hematopoietic stem cells><Hereditary><Heterograft><Heterologous Transplantation><Homolog of Drosophila TOLL><Homologous Chemotactic Cytokines><Immune><Immunes><In Vitro><Individual><Infection><Inflammation><Inflammatory><Inflammatory Response><Inherited><Intercrines><Intracellular Communication and Signaling><Investigators><K lymphocyte><Laboratories><Ligands><Long-term infection><Malignant Hematopoietic Neoplasm><Malignant Neoplasms><Malignant Tumor><Marrow monocyte><Marrow platelet><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Mice><Mice Mammals><MonoMAC><Monosomy 7><Murine><Mus><Mutation><Mycoses><Myelodysplastic Disease><Myelodysplastic Syndromes><Myeloid Disease><Myeloid Malignancy><Myeloid Neoplasm><Myeloid Tumor><Myeloproliferative Disorders><Myeloproliferative Tumors><Myeloproliferative disease><NIH><NK Cells><National Institutes of Health><Natural Killer Cells><Oregon><PEBP2A2><PEBP2aB><Pathogenicity><Pathway interactions><Patients><Pennsylvania><Platelets><Pre-Clinical Model><Preclinical Models><Precursor T Lymphoblastic Leukemia><Predisposition><RUNX1><RUNX1 gene><Refractory Anemia with an Excess of Blasts><Refractory anaemia with excess blasts><Research Personnel><Researchers><Risk><Role><SIS cytokines><Sampling><Science><Signal Transduction><Signal Transduction Systems><Signaling><Smoldering Leukemia><Somatic Mutation><Source><Strains Cell Lines><Stromal Cells><Susceptibility><Syndrome><Systematics><T-Cell Type Acute Leukemia><T-lineage acute lymphoblastic leukemia><TLR4><TLR4 gene><Testing><Thrombocytes><Tissue Growth><Toll Homologue><Transcription Factor Proto-Oncogene><Transcription factor genes><Translational Research><Translational Science><United States National Institutes of Health><Universities><Variant><Variation><Veiled Cells><Viral><Wisconsin><Work><Xenograft><Xenograft procedure><Xenotransplantation><acute infection><ages><benchmark><biological signal transduction><biomarker identification><blood cancer><blood cell progenitor><blood progenitor><blood progenitor cell expansion><blood progenitor expansion><blood stem cell><blood stem cell expansion><blood-forming stem cell><cancer of blood><cancer of the blood><cell growth><cellular differentiation><chemoattractant cytokine><chemokine><chronic infection><clinical center><clinical test><clonal expansions in the blood><clonal hematopoiesis><clones in hematopoietic cells><cultured cell line><cytokine><derepression><design><designing><developmental><driver lesion><driver mutation><driving><drug use><fungal infection><fungus infection><gene defect><genome mutation><hematopoietic cell clones><hematopoietic progenitor><hematopoietic progenitor cell expansion><hematopoietic progenitor expansion><hematopoietic stem cell clonality><hematopoietic stem cell expansion><hematopoietic stem progenitor cell><hemopoietic><hemopoietic progenitor><hemopoietic stem cell><high risk><hypoimmunity><identification of biomarkers><identification of new biomarkers><immune deficiency><immunodeficiency><improved><inflammatory environment><inflammatory milieu><innovate><innovation><innovative><interest><juvenile><juvenile human><leukemia><leukemogenesis><malignancy><marker identification><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><monocyte><mouse model><murine model><mutant><mutant allele><mutation carrier><myelodysplasia><myeloproliferative neoplasm><neoplasm/cancer><new approaches><non-tuberculosis mycobacteria><non-tuberculosis mycobacterial><non-tuberculous mycobacteria><non-tuberculous mycobacterial><nontuberculosis mycobacterial><nontuberculous mycobacteria><nontuberculous mycobacterial><novel approaches><novel strategies><novel strategy><ontogeny><pathway><persistent infection><prevent><preventing><progenitor Cell growth><progenitor growth><programs><research clinical testing><response><social role><somatic variant><stem cell growth><systemic inflammation><systemic inflammatory response><toll-like receptor 4><transcription factor><translation research><translational investigation><unclassified variant><variant of uncertain clinical significance><variant of uncertain significance><variant of undetermined significance><variant of unknown significance><xeno-transplant><xeno-transplantation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LUCY Ann GODLEY

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Solid budget
Team-scale grant
$497,412
FY 2025

Project Title

The role of inflammation in driving leukemogenesis in germline predisposition syndromes

Grant Number:

5U01CA257666-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2022

End Date:

4/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Germline predisposition to hematopoietic malignancies (HMs) is more common than previously appreciated, but individuals are spread throughout the country, with few local experts. The NIH provides focused clinics for patients with germline GATA2 mutations under Drs. Holland and Hickst...

Research Terms

<AML1><AMLCR1><Acceleration><Acute T Cell Leukemia><Acute T-Cell Lymphoblastic Leukemia><Acute T-Cell Lymphocytic Leukemia><Acute T-Lymphocytic Leukemia><Adolescent><Adolescent Youth><Age><Assay><Automobile Driving><B blood cells><B cell><B cell malignancy><B cells><B lymphoid malignancy><B-Cells><B-Lymphocytes><B-cell><Basal Transcription Factor><Basal transcription factor genes><Benchmarking><Benign><Best Practice Analysis><Bioassay><Biological Assay><Blood Platelets><Blood Precursor Cell><Blood monocyte><Bone marrow failure><CBFA2><Cancers><Cell Body><Cell Communication and Signaling><Cell Differentiation><Cell Differentiation process><Cell Line><Cell Signaling><CellLine><Cells><Cellular Expansion><Cellular Growth><Characteristics><Chemotactic Cytokines><Chicago><Classification><Clinic><Clinical Evaluation><Clinical Testing><Clinical Trials><Clinical assessments><Clonal Expansion><Clonal expansion of hematopoietic cells><Clonal expansion of hematopoietic stem cells><Clonal hematopoietic expansion><Collection><Country><Cytotoxic cell><DNA mutation><Data><Defect><Dendritic Cells><Development><Differentiation and Growth><Disease><Disorder><Drug usage><Dysmyelopoietic Syndromes><EXTMR><Emberger syndrome><Extramural><Extramural Activities><Family><Fungus Diseases><GATA2 deficiency><GATA2 haploinsufficiency><Gene Alteration><Gene Mutation><General Population><General Public><General Transcription Factor Gene><General Transcription Factors><Generalized Growth><Genetic Change><Genetic defect><Genetic mutation><Germ Lines><Growth><HSC expansion><Health><Hematopoietic><Hematopoietic Cell Tumor><Hematopoietic Malignancies><Hematopoietic Neoplasms><Hematopoietic Neoplasms including Lymphomas><Hematopoietic Progenitor Cells><Hematopoietic Tumor><Hematopoietic and Lymphoid Cell Neoplasm><Hematopoietic and Lymphoid Neoplasms><Hematopoietic stem cells><Hereditary><Heterograft><Heterologous Transplantation><Homolog of Drosophila TOLL><Homologous Chemotactic Cytokines><Immune><Immunes><In Vitro><Individual><Infection><Inflammation><Inflammatory><Inflammatory Response><Inherited><Intercrines><Intracellular Communication and Signaling><Investigators><K lymphocyte><Laboratories><Ligands><Long-term infection><Malignant Hematopoietic Neoplasm><Malignant Neoplasms><Malignant Tumor><Marrow monocyte><Marrow platelet><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Mice><Mice Mammals><MonoMAC><Monosomy 7><Murine><Mus><Mutation><Mycoses><Myelodysplastic Disease><Myelodysplastic Syndromes><Myeloid Disease><Myeloid Malignancy><Myeloid Neoplasm><Myeloid Tumor><Myeloproliferative Disorders><Myeloproliferative Tumors><Myeloproliferative disease><NIH><NK Cells><National Institutes of Health><Natural Killer Cells><Oregon><PEBP2A2><PEBP2aB><Pathogenicity><Pathway interactions><Patients><Pennsylvania><Platelets><Pre-Clinical Model><Preclinical Models><Precursor T Lymphoblastic Leukemia><Predisposition><RUNX1><RUNX1 gene><Refractory Anemia with an Excess of Blasts><Refractory anaemia with excess blasts><Research Personnel><Researchers><Risk><Role><SIS cytokines><Sampling><Science><Signal Transduction><Signal Transduction Systems><Signaling><Smoldering Leukemia><Somatic Mutation><Source><Strains Cell Lines><Stromal Cells><Susceptibility><Syndrome><Systematics><T-Cell Type Acute Leukemia><T-lineage acute lymphoblastic leukemia><TLR4><TLR4 gene><Testing><Thrombocytes><Tissue Growth><Toll Homologue><Transcription Factor Proto-Oncogene><Transcription factor genes><Translational Research><Translational Science><United States National Institutes of Health><Universities><Variant><Variation><Veiled Cells><Viral><Wisconsin><Work><Xenograft><Xenograft procedure><Xenotransplantation><acute infection><ages><benchmark><biological signal transduction><biomarker identification><blood cancer><blood cell progenitor><blood progenitor><blood progenitor cell expansion><blood progenitor expansion><blood stem cell><blood stem cell expansion><blood-forming stem cell><cancer of blood><cancer of the blood><cell growth><cellular differentiation><chemoattractant cytokine><chemokine><chronic infection><clinical center><clinical test><clonal expansions in the blood><clonal hematopoiesis><clones in hematopoietic cells><cultured cell line><cytokine><derepression><design><designing><developmental><driver lesion><driver mutation><driving><drug use><fungal infection><fungus infection><gene defect><genome mutation><hematopoietic cell clones><hematopoietic progenitor><hematopoietic progenitor cell expansion><hematopoietic progenitor expansion><hematopoietic stem cell clonality><hematopoietic stem cell expansion><hematopoietic stem progenitor cell><hemopoietic><hemopoietic progenitor><hemopoietic stem cell><high risk><hypoimmunity><identification of biomarkers><identification of new biomarkers><immune deficiency><immunodeficiency><improved><inflammatory environment><inflammatory milieu><innovate><innovation><innovative><interest><juvenile><juvenile human><leukemia><leukemogenesis><malignancy><marker identification><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><monocyte><mouse model><murine model><mutant><mutant allele><mutation carrier><myelodysplasia><myeloproliferative neoplasm><neoplasm/cancer><new approaches><non-tuberculosis mycobacteria><non-tuberculosis mycobacterial><non-tuberculous mycobacteria><non-tuberculous mycobacterial><nontuberculosis mycobacterial><nontuberculous mycobacteria><nontuberculous mycobacterial><novel approaches><novel strategies><novel strategy><ontogeny><pathway><persistent infection><prevent><preventing><progenitor Cell growth><progenitor growth><programs><research clinical testing><response><social role><somatic variant><stem cell growth><systemic inflammation><systemic inflammatory response><toll-like receptor 4><transcription factor><translation research><translational investigation><unclassified variant><variant of uncertain clinical significance><variant of uncertain significance><variant of undetermined significance><variant of unknown significance><xeno-transplant><xeno-transplantation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

NANCY SPECK

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Solid budget
Team-scale grant
$497,412
FY 2025

Project Title

The role of inflammation in driving leukemogenesis in germline predisposition syndromes

Grant Number:

5U01CA257666-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2022

End Date:

4/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Germline predisposition to hematopoietic malignancies (HMs) is more common than previously appreciated, but individuals are spread throughout the country, with few local experts. The NIH provides focused clinics for patients with germline GATA2 mutations under Drs. Holland and Hickst...

Research Terms

<AML1><AMLCR1><Acceleration><Acute T Cell Leukemia><Acute T-Cell Lymphoblastic Leukemia><Acute T-Cell Lymphocytic Leukemia><Acute T-Lymphocytic Leukemia><Adolescent><Adolescent Youth><Age><Assay><Automobile Driving><B blood cells><B cell><B cell malignancy><B cells><B lymphoid malignancy><B-Cells><B-Lymphocytes><B-cell><Basal Transcription Factor><Basal transcription factor genes><Benchmarking><Benign><Best Practice Analysis><Bioassay><Biological Assay><Blood Platelets><Blood Precursor Cell><Blood monocyte><Bone marrow failure><CBFA2><Cancers><Cell Body><Cell Communication and Signaling><Cell Differentiation><Cell Differentiation process><Cell Line><Cell Signaling><CellLine><Cells><Cellular Expansion><Cellular Growth><Characteristics><Chemotactic Cytokines><Chicago><Classification><Clinic><Clinical Evaluation><Clinical Testing><Clinical Trials><Clinical assessments><Clonal Expansion><Clonal expansion of hematopoietic cells><Clonal expansion of hematopoietic stem cells><Clonal hematopoietic expansion><Collection><Country><Cytotoxic cell><DNA mutation><Data><Defect><Dendritic Cells><Development><Differentiation and Growth><Disease><Disorder><Drug usage><Dysmyelopoietic Syndromes><EXTMR><Emberger syndrome><Extramural><Extramural Activities><Family><Fungus Diseases><GATA2 deficiency><GATA2 haploinsufficiency><Gene Alteration><Gene Mutation><General Population><General Public><General Transcription Factor Gene><General Transcription Factors><Generalized Growth><Genetic Change><Genetic defect><Genetic mutation><Germ Lines><Growth><HSC expansion><Health><Hematopoietic><Hematopoietic Cell Tumor><Hematopoietic Malignancies><Hematopoietic Neoplasms><Hematopoietic Neoplasms including Lymphomas><Hematopoietic Progenitor Cells><Hematopoietic Tumor><Hematopoietic and Lymphoid Cell Neoplasm><Hematopoietic and Lymphoid Neoplasms><Hematopoietic stem cells><Hereditary><Heterograft><Heterologous Transplantation><Homolog of Drosophila TOLL><Homologous Chemotactic Cytokines><Immune><Immunes><In Vitro><Individual><Infection><Inflammation><Inflammatory><Inflammatory Response><Inherited><Intercrines><Intracellular Communication and Signaling><Investigators><K lymphocyte><Laboratories><Ligands><Long-term infection><Malignant Hematopoietic Neoplasm><Malignant Neoplasms><Malignant Tumor><Marrow monocyte><Marrow platelet><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Mice><Mice Mammals><MonoMAC><Monosomy 7><Murine><Mus><Mutation><Mycoses><Myelodysplastic Disease><Myelodysplastic Syndromes><Myeloid Disease><Myeloid Malignancy><Myeloid Neoplasm><Myeloid Tumor><Myeloproliferative Disorders><Myeloproliferative Tumors><Myeloproliferative disease><NIH><NK Cells><National Institutes of Health><Natural Killer Cells><Oregon><PEBP2A2><PEBP2aB><Pathogenicity><Pathway interactions><Patients><Pennsylvania><Platelets><Pre-Clinical Model><Preclinical Models><Precursor T Lymphoblastic Leukemia><Predisposition><RUNX1><RUNX1 gene><Refractory Anemia with an Excess of Blasts><Refractory anaemia with excess blasts><Research Personnel><Researchers><Risk><Role><SIS cytokines><Sampling><Science><Signal Transduction><Signal Transduction Systems><Signaling><Smoldering Leukemia><Somatic Mutation><Source><Strains Cell Lines><Stromal Cells><Susceptibility><Syndrome><Systematics><T-Cell Type Acute Leukemia><T-lineage acute lymphoblastic leukemia><TLR4><TLR4 gene><Testing><Thrombocytes><Tissue Growth><Toll Homologue><Transcription Factor Proto-Oncogene><Transcription factor genes><Translational Research><Translational Science><United States National Institutes of Health><Universities><Variant><Variation><Veiled Cells><Viral><Wisconsin><Work><Xenograft><Xenograft procedure><Xenotransplantation><acute infection><ages><benchmark><biological signal transduction><biomarker identification><blood cancer><blood cell progenitor><blood progenitor><blood progenitor cell expansion><blood progenitor expansion><blood stem cell><blood stem cell expansion><blood-forming stem cell><cancer of blood><cancer of the blood><cell growth><cellular differentiation><chemoattractant cytokine><chemokine><chronic infection><clinical center><clinical test><clonal expansions in the blood><clonal hematopoiesis><clones in hematopoietic cells><cultured cell line><cytokine><derepression><design><designing><developmental><driver lesion><driver mutation><driving><drug use><fungal infection><fungus infection><gene defect><genome mutation><hematopoietic cell clones><hematopoietic progenitor><hematopoietic progenitor cell expansion><hematopoietic progenitor expansion><hematopoietic stem cell clonality><hematopoietic stem cell expansion><hematopoietic stem progenitor cell><hemopoietic><hemopoietic progenitor><hemopoietic stem cell><high risk><hypoimmunity><identification of biomarkers><identification of new biomarkers><immune deficiency><immunodeficiency><improved><inflammatory environment><inflammatory milieu><innovate><innovation><innovative><interest><juvenile><juvenile human><leukemia><leukemogenesis><malignancy><marker identification><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><monocyte><mouse model><murine model><mutant><mutant allele><mutation carrier><myelodysplasia><myeloproliferative neoplasm><neoplasm/cancer><new approaches><non-tuberculosis mycobacteria><non-tuberculosis mycobacterial><non-tuberculous mycobacteria><non-tuberculous mycobacterial><nontuberculosis mycobacterial><nontuberculous mycobacteria><nontuberculous mycobacterial><novel approaches><novel strategies><novel strategy><ontogeny><pathway><persistent infection><prevent><preventing><progenitor Cell growth><progenitor growth><programs><research clinical testing><response><social role><somatic variant><stem cell growth><systemic inflammation><systemic inflammatory response><toll-like receptor 4><transcription factor><translation research><translational investigation><unclassified variant><variant of uncertain clinical significance><variant of uncertain significance><variant of undetermined significance><variant of unknown significance><xeno-transplant><xeno-transplantation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Daniel Conlon Brennan

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$249,378
FY 2025

Project Title

3/14 ApoL1 Long-Term Kidney Transplantation Outcomes Network (Apollo) Clinical Center

Grant Number:

5U01DK116042-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary Genetic variants in APOL1 commonly found in people of Western Sub-Saharan Africa ancestry are associated with kidney diseases such as Focal Segmental Glomerulosclerosis, Hypertension Attributed-End Stage Kidney Disease, and HIV-Associated Nephropathy. The presence of 2 APOL1- renal r...

Research Terms

<AIDS Nephropathy><AIDS-Associated Nephropathy><AIDS-Related Nephropathy><APOL-I><APOL1><APOL1 gene><Acceleration><Active Follow-up><Acute><Address><Africa South of the Sahara><African American><African ancestry><African descent><Afro American><Afroamerican><Albumins><Alleles><Allelomorphs><Allografting><American><Antibodies><Apolipoproteins><Bacterial Infections><Biological><Biopsy><Blood><Blood Reticuloendothelial System><Blood Serum><CC3><Clinical><Clinical Data><Consent><Cost Savings><Counseling><Creatinine><DNA><Data><Deoxyribonucleic Acid><Disparities><Disparity><ESKD><ESRD><Education><Educational aspects><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Enrollment><Ensure><European><Evaluation><FSGS><Face><Failure><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Future><Gene variant><Genes><Genetic><Genotype><Geography><Graft Survival><HIV-Associated Nephropathy><HIV-Related Nephropathy><HL-A Antigens><HLA Antigens><HTATIP2 gene><Health Care Costs><Health Costs><Human Immunodeficiency Virus-Associated Nephropathy><Human Leukocyte Antigens><Hypertension><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Investigators><Kidney><Kidney Diseases><Kidney Failure><Kidney Grafting><Kidney Insufficiency><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Lesion><Leukocyte Antigens><Living Donors><Long-term Follow-up><Measures><Medical><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nephropathy><Organ><Outcome><Outcome Assessment><Outcome Study><Participant><Patients><Pattern><Persons><Phase><Phenotype><Policies><Prevalence><Proteinuria><QOL><Quality of life><Recurrent disease><Registries><Relapsed Disease><Renal Disease><Renal Failure><Renal Grafting><Renal Insufficiency><Renal Transplantation><Renal Transplants><Renal function><Reporting><Research><Research Design><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Risk><Risk-associated variant><Role><Safety><Sampling><Serum><Site><Slide><Specimen><Study Type><Sub-Saharan Africa><Subsaharan Africa><TIP30><Time><Transplant Recipients><Transplantation><UNOS><United Network for Organ Sharing><United States><United States National Institutes of Health><Universities><Urine><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Viral Diseases><Virus Diseases><Vital Status><active followup><allelic variant><bacteria infection><bacterial disease><biologic><clinical center><clinical practice><cohort><deceased donor><deceased organ donors><depository><differences due to race><differences in race><differs by race><differs in race><digital pathology><enroll><ethnic difference><ethnicity difference><faces><facial><follow up><follow-up><followed up><followup><functional outcomes><gene interaction><genetic variant><genomic variant><graft failure><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><kidney allograft><kidney biopsy><kidney disorder><kidney function><kidney tx><long-term followup><novel><post-transplant><post-transplantation><posthumous donors><posthumous organ donor><posttransplant><posttransplantation><primary outcome><programs><prospective><race based differences><race differences><race related differences><racial difference><racially different><rate of change><recruit><renal><renal allograft><renal biopsy><renal disorder><repository><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><secondary outcome><social role><study design><transplant><transplant patient><viral infection><virus infection><virus-induced disease>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Krista L Lentine

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$249,378
FY 2025

Project Title

3/14 ApoL1 Long-Term Kidney Transplantation Outcomes Network (Apollo) Clinical Center

Grant Number:

5U01DK116042-09

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary Genetic variants in APOL1 commonly found in people of Western Sub-Saharan Africa ancestry are associated with kidney diseases such as Focal Segmental Glomerulosclerosis, Hypertension Attributed-End Stage Kidney Disease, and HIV-Associated Nephropathy. The presence of 2 APOL1- renal r...

Research Terms

<AIDS Nephropathy><AIDS-Associated Nephropathy><AIDS-Related Nephropathy><APOL-I><APOL1><APOL1 gene><Acceleration><Active Follow-up><Acute><Address><Africa South of the Sahara><African American><African ancestry><African descent><Afro American><Afroamerican><Albumins><Alleles><Allelomorphs><Allografting><American><Antibodies><Apolipoproteins><Bacterial Infections><Biological><Biopsy><Blood><Blood Reticuloendothelial System><Blood Serum><CC3><Clinical><Clinical Data><Consent><Cost Savings><Counseling><Creatinine><DNA><Data><Deoxyribonucleic Acid><Disparities><Disparity><ESKD><ESRD><Education><Educational aspects><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Enrollment><Ensure><European><Evaluation><FSGS><Face><Failure><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Future><Gene variant><Genes><Genetic><Genotype><Geography><Graft Survival><HIV-Associated Nephropathy><HIV-Related Nephropathy><HL-A Antigens><HLA Antigens><HTATIP2 gene><Health Care Costs><Health Costs><Human Immunodeficiency Virus-Associated Nephropathy><Human Leukocyte Antigens><Hypertension><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Investigators><Kidney><Kidney Diseases><Kidney Failure><Kidney Grafting><Kidney Insufficiency><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Lesion><Leukocyte Antigens><Living Donors><Long-term Follow-up><Measures><Medical><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nephropathy><Organ><Outcome><Outcome Assessment><Outcome Study><Participant><Patients><Pattern><Persons><Phase><Phenotype><Policies><Prevalence><Proteinuria><QOL><Quality of life><Recurrent disease><Registries><Relapsed Disease><Renal Disease><Renal Failure><Renal Grafting><Renal Insufficiency><Renal Transplantation><Renal Transplants><Renal function><Reporting><Research><Research Design><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Risk><Risk-associated variant><Role><Safety><Sampling><Serum><Site><Slide><Specimen><Study Type><Sub-Saharan Africa><Subsaharan Africa><TIP30><Time><Transplant Recipients><Transplantation><UNOS><United Network for Organ Sharing><United States><United States National Institutes of Health><Universities><Urine><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Viral Diseases><Virus Diseases><Vital Status><active followup><allelic variant><bacteria infection><bacterial disease><biologic><clinical center><clinical practice><cohort><deceased donor><deceased organ donors><depository><differences due to race><differences in race><differs by race><differs in race><digital pathology><enroll><ethnic difference><ethnicity difference><faces><facial><follow up><follow-up><followed up><followup><functional outcomes><gene interaction><genetic variant><genomic variant><graft failure><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><kidney allograft><kidney biopsy><kidney disorder><kidney function><kidney tx><long-term followup><novel><post-transplant><post-transplantation><posthumous donors><posthumous organ donor><posttransplant><posttransplantation><primary outcome><programs><prospective><race based differences><race differences><race related differences><racial difference><racially different><rate of change><recruit><renal><renal allograft><renal biopsy><renal disorder><repository><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><secondary outcome><social role><study design><transplant><transplant patient><viral infection><virus infection><virus-induced disease>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Hung N Luu

AUBURN UNIVERSITY AT AUBURN, Auburn, AL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$234,230
FY 2025

Project Title

An integrated, multi-cohort approach for cancer health disparities and risk assessment

Grant Number:

3U01CA274573-03S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2023

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

SUMMARY Of the 8,314 drug indications entering Phase II clinical trials from 2011–2020, 85% failed. This could have been greatly reduced if a drug could be administered only to the people most likely to respond. At the same time, over a million women/year receive unnecessary treatments due to breast...

Research Terms

<Abscission><Active Follow-up><Address><Bayesian Modeling><Bayesian adaptive designs><Bayesian adaptive models><Bayesian belief network><Bayesian belief updating model><Bayesian framework><Bayesian hierarchical model><Bayesian network model><Bayesian nonparametric models><Bayesian spatial data model><Bayesian spatial image models><Bayesian spatial models><Bayesian statistical models><Bayesian tracking algorithms><Big Data><BigData><Breast Cancer><Cancer Center><Cancer Prognosis><Cancers><Clinical><Clinical Research><Clinical Study><Cohort Analyses><Cohort Analysis><Controlled Study><Cox Proportional Hazards Models><DNA mutation><Data><Defense Mechanisms><Development><Diagnosis><Disparities><Disparity><Drug resistance><Drugs><Ensure><Ethnic Origin><Ethnicity><Evolution><Excision><Extirpation><Failure><Feedback><Future><Genetic Change><Genetic defect><Genetic mutation><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Goals><Grant><Groups at risk><Health><Hepatic Cancer><Hospitals><Incidence><Intervention><Investigation><Investigators><Journals><Knowledge><Letters><Location><Magazine><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of liver><Malignant neoplasm of lung><Medical center><Medication><Medicine><Messenger RNA><Meta-Analysis><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Methodist Church><Methodists><Methodology><Methods><Methylation><MicroRNAs><Molecular Fingerprinting><Molecular Profiling><Morbidity><Morbidity - disease rate><Multiomic Data><Mutation><NIH><NSCLC><NSCLC - Non-Small Cell Lung Cancer><National Institutes of Health><Neoplasm Metastasis><Network Analysis><New England><New York><Non-Small Cell Lung Cancer><Non-Small-Cell Lung Carcinoma><Northeastern United States><Parents><Pathway Analysis><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><People at risk><Persons><Persons at risk><Pharmaceutical Preparations><Phase><Phase 2 Clinical Trials><Phase II Clinical Trials><Population><Population Heterogeneity><Populations at Risk><Preventative service><Preventive service><Prognosis><Public Health><Pulmonary Cancer><Pulmonary malignant Neoplasm><Race><Races><Records><Recurrence><Recurrent><Removal><Reporting><Reproducibility><Research><Research Personnel><Researchers><Risk><Risk Assessment><Risk Factors><Secondary Neoplasm><Secondary Tumor><Sn element><Stannum><Subgroup><Surgical Removal><TCGA><Techniques><Technology><Testing><The Cancer Genome Atlas><Time><Tin><Tumor Subtype><United States National Institutes of Health><Validation><Veterans><Viet Nam><Vietnam><Woman><Work><active followup><aggressive therapy><aggressive treatment><biobank><biorepository><cBioPortal><cancer disparity><cancer health disparity><cancer metastasis><cancer-related health disparity><cohort><cost><depository><developmental><disparity in cancer><disparity in health><diverse populations><drug resistant><drug/agent><experience><follow up><follow-up><followed up><followup><genome mutation><geographic site><health disparity><heterogeneous population><high dimensionality><high risk><improved><innovate><innovation><innovative><liver cancer><liver malignancy><lung cancer><mRNA><malignancy><malignant breast tumor><malignant liver tumor><miRNA><molecular profile><molecular signature><mortality><multiomics><multiple omic data><multiple omics><neoplasm/cancer><new approaches><novel><novel approaches><novel strategies><novel strategy><panomics><parent><parent grant><pathway><patient oriented outcomes><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><phase II protocol><population diversity><programs><psychological defense mechanism><public repository><publicly accessible repository><publicly available repository><racial><racial background><racial origin><randomized, clinical trials><repository><resection><resistance to Drug><resistant to Drug><response><response to therapy><response to treatment><screening services><socio-economic><socio-economically><socioeconomically><socioeconomics><therapeutic response><therapy response><tool><treatment response><treatment responsiveness><tumor cell metastasis><unnecessary treatment><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tin C Nguyen

AUBURN UNIVERSITY AT AUBURN, Auburn, AL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$234,230
FY 2025

Project Title

An integrated, multi-cohort approach for cancer health disparities and risk assessment

Grant Number:

3U01CA274573-03S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2023

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

SUMMARY Of the 8,314 drug indications entering Phase II clinical trials from 2011–2020, 85% failed. This could have been greatly reduced if a drug could be administered only to the people most likely to respond. At the same time, over a million women/year receive unnecessary treatments due to breast...

Research Terms

<Abscission><Active Follow-up><Address><Bayesian Modeling><Bayesian adaptive designs><Bayesian adaptive models><Bayesian belief network><Bayesian belief updating model><Bayesian framework><Bayesian hierarchical model><Bayesian network model><Bayesian nonparametric models><Bayesian spatial data model><Bayesian spatial image models><Bayesian spatial models><Bayesian statistical models><Bayesian tracking algorithms><Big Data><BigData><Breast Cancer><Cancer Center><Cancer Prognosis><Cancers><Clinical><Clinical Research><Clinical Study><Cohort Analyses><Cohort Analysis><Controlled Study><Cox Proportional Hazards Models><DNA mutation><Data><Defense Mechanisms><Development><Diagnosis><Disparities><Disparity><Drug resistance><Drugs><Ensure><Ethnic Origin><Ethnicity><Evolution><Excision><Extirpation><Failure><Feedback><Future><Genetic Change><Genetic defect><Genetic mutation><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Goals><Grant><Groups at risk><Health><Hepatic Cancer><Hospitals><Incidence><Intervention><Investigation><Investigators><Journals><Knowledge><Letters><Location><Magazine><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of liver><Malignant neoplasm of lung><Medical center><Medication><Medicine><Messenger RNA><Meta-Analysis><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Methodist Church><Methodists><Methodology><Methods><Methylation><MicroRNAs><Molecular Fingerprinting><Molecular Profiling><Morbidity><Morbidity - disease rate><Multiomic Data><Mutation><NIH><NSCLC><NSCLC - Non-Small Cell Lung Cancer><National Institutes of Health><Neoplasm Metastasis><Network Analysis><New England><New York><Non-Small Cell Lung Cancer><Non-Small-Cell Lung Carcinoma><Northeastern United States><Parents><Pathway Analysis><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><People at risk><Persons><Persons at risk><Pharmaceutical Preparations><Phase><Phase 2 Clinical Trials><Phase II Clinical Trials><Population><Population Heterogeneity><Populations at Risk><Preventative service><Preventive service><Prognosis><Public Health><Pulmonary Cancer><Pulmonary malignant Neoplasm><Race><Races><Records><Recurrence><Recurrent><Removal><Reporting><Reproducibility><Research><Research Personnel><Researchers><Risk><Risk Assessment><Risk Factors><Secondary Neoplasm><Secondary Tumor><Sn element><Stannum><Subgroup><Surgical Removal><TCGA><Techniques><Technology><Testing><The Cancer Genome Atlas><Time><Tin><Tumor Subtype><United States National Institutes of Health><Validation><Veterans><Viet Nam><Vietnam><Woman><Work><active followup><aggressive therapy><aggressive treatment><biobank><biorepository><cBioPortal><cancer disparity><cancer health disparity><cancer metastasis><cancer-related health disparity><cohort><cost><depository><developmental><disparity in cancer><disparity in health><diverse populations><drug resistant><drug/agent><experience><follow up><follow-up><followed up><followup><genome mutation><geographic site><health disparity><heterogeneous population><high dimensionality><high risk><improved><innovate><innovation><innovative><liver cancer><liver malignancy><lung cancer><mRNA><malignancy><malignant breast tumor><malignant liver tumor><miRNA><molecular profile><molecular signature><mortality><multiomics><multiple omic data><multiple omics><neoplasm/cancer><new approaches><novel><novel approaches><novel strategies><novel strategy><panomics><parent><parent grant><pathway><patient oriented outcomes><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><phase II protocol><population diversity><programs><psychological defense mechanism><public repository><publicly accessible repository><publicly available repository><racial><racial background><racial origin><randomized, clinical trials><repository><resection><resistance to Drug><resistant to Drug><response><response to therapy><response to treatment><screening services><socio-economic><socio-economically><socioeconomically><socioeconomics><therapeutic response><therapy response><tool><treatment response><treatment responsiveness><tumor cell metastasis><unnecessary treatment><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Braden Kuo

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$215,000
FY 2025

Project Title

A Consortium for Gut-Brain Communication in Parkinson's Disease

Grant Number:

3U01DK140933-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract We plan to additionally support the initial participation and conduct in the NIH U01 Consortium for Gut-Brain Communication in Parkinson’s Disease (PD) (GBPDC) including contribution of PD patients across the spectrum of disease, with and without GI symptoms and age/sex matc...

Research Terms

<Affect><Age><Alimentary Canal><Anal Sphincter><Barium swallow><Biological><Brain><Brain Nervous System><CNS Nervous System><Cell Communication and Signaling><Cell Signaling><Central Nervous System><Clinical><Cohort Studies><Concurrent Studies><DA Neuron><Degenerative Neurologic Disorders><Deglutition><Dependence><Dermatologic biopsy><Development><Digestive Tract><Disease><Disorder><Dopamine neuron><Drugs><Dysfunction><Emesis><Encephalon><Esophagus><Functional disorder><Funding><Funding Opportunities><GI Tract><Gastrointestinal Tract><Gastrointestinal tract structure><General Hospitals><Health><Household><Individual><Intracellular Communication and Signaling><Manometry><Manometry Biochemistry><Massachusetts><Measures><Medication><Motility><NAC precursor><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nausea><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neuraxis><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><PARK1 protein><PARK4 protein><Paralysis Agitans><Parkinson><Parkinson Disease><Participant><Pathologic Processes><Pathological Processes><Patients><Pharmaceutical Preparations><Pharyngeal structure><Pharynx><Phenotype><Phosphorylation><Physiology><Physiopathology><Population><Primary Parkinsonism><Proctosigmoidoscopy><Protein Phosphorylation><Protocol><Protocols documentation><QOL><Quality of life><REM Behavior Disorder><REM Sleep Behavior Disorder><Rapid Eye Movement Behavior Disorder><Rapid Eye Movement Sleep Behavior Disorder><Rectum><Registries><SNCA><SNCA protein><Sampling><Sigmoid><Sigmoid colon><Sigmoidoscopy><Signal Transduction><Signal Transduction Systems><Signaling><Site><Skin><Stomach><Substantia Nigra><Substantia nigra structure><Swallowing><Symptoms><System><Throat><United States National Institutes of Health><Upper GI><Upper GI Tract><Upper Gastrointestinal Tract><Upper digestive tract structure><Vomiting><a-syn><a-synuclein><absorption><ages><alimentary tract><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><biologic><biological signal transduction><circadian><clinical research site><clinical site><cohort><cutaneous biopsy><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><developmental><digestive canal><dopaminergic neuron><drug/agent><dysmotility><dysmotility syndrome><experience><gastric><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><interest><motility disorder><motor deficit><motor symptom><neurodegenerative illness><non A-beta component of AD amyloid><non A4 component of amyloid precursor><non-motor symptom><nonmotor symptom><pathophysiology><protocol development><quality of sleep><recruit><sex><skin biopsy><sleep quality><sphincter ani muscle structure><stem><α synuclein gene><α-syn><α-synuclein>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Aleksandar Videnovic

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$215,000
FY 2025

Project Title

A Consortium for Gut-Brain Communication in Parkinson's Disease

Grant Number:

3U01DK140933-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract We plan to additionally support the initial participation and conduct in the NIH U01 Consortium for Gut-Brain Communication in Parkinson’s Disease (PD) (GBPDC) including contribution of PD patients across the spectrum of disease, with and without GI symptoms and age/sex matc...

Research Terms

<Affect><Age><Alimentary Canal><Anal Sphincter><Barium swallow><Biological><Brain><Brain Nervous System><CNS Nervous System><Cell Communication and Signaling><Cell Signaling><Central Nervous System><Clinical><Cohort Studies><Concurrent Studies><DA Neuron><Degenerative Neurologic Disorders><Deglutition><Dependence><Dermatologic biopsy><Development><Digestive Tract><Disease><Disorder><Dopamine neuron><Drugs><Dysfunction><Emesis><Encephalon><Esophagus><Functional disorder><Funding><Funding Opportunities><GI Tract><Gastrointestinal Tract><Gastrointestinal tract structure><General Hospitals><Health><Household><Individual><Intracellular Communication and Signaling><Manometry><Manometry Biochemistry><Massachusetts><Measures><Medication><Motility><NAC precursor><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nausea><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neuraxis><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><PARK1 protein><PARK4 protein><Paralysis Agitans><Parkinson><Parkinson Disease><Participant><Pathologic Processes><Pathological Processes><Patients><Pharmaceutical Preparations><Pharyngeal structure><Pharynx><Phenotype><Phosphorylation><Physiology><Physiopathology><Population><Primary Parkinsonism><Proctosigmoidoscopy><Protein Phosphorylation><Protocol><Protocols documentation><QOL><Quality of life><REM Behavior Disorder><REM Sleep Behavior Disorder><Rapid Eye Movement Behavior Disorder><Rapid Eye Movement Sleep Behavior Disorder><Rectum><Registries><SNCA><SNCA protein><Sampling><Sigmoid><Sigmoid colon><Sigmoidoscopy><Signal Transduction><Signal Transduction Systems><Signaling><Site><Skin><Stomach><Substantia Nigra><Substantia nigra structure><Swallowing><Symptoms><System><Throat><United States National Institutes of Health><Upper GI><Upper GI Tract><Upper Gastrointestinal Tract><Upper digestive tract structure><Vomiting><a-syn><a-synuclein><absorption><ages><alimentary tract><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><biologic><biological signal transduction><circadian><clinical research site><clinical site><cohort><cutaneous biopsy><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><developmental><digestive canal><dopaminergic neuron><drug/agent><dysmotility><dysmotility syndrome><experience><gastric><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><interest><motility disorder><motor deficit><motor symptom><neurodegenerative illness><non A-beta component of AD amyloid><non A4 component of amyloid precursor><non-motor symptom><nonmotor symptom><pathophysiology><protocol development><quality of sleep><recruit><sex><skin biopsy><sleep quality><sphincter ani muscle structure><stem><α synuclein gene><α-syn><α-synuclein>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christopher G. Goetz

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$214,082
FY 2025

Project Title

The Bidirectional Gut-Microbiota-Brain Axis in Parkinson’s disease: integrating mechanistic biomarkers of disease severity and progression

Grant Number:

3U01DK140923-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT This Administrative Supplement Request to U01 DK140923 at Rush University Medical Center (RUMC) / Medical University of South Carolina (MUSC) will significantly enhance the Gut Brain Parkinson's Disease Consortium (GBPDC) by integrating additional crucial gastrointestinal an...

Research Terms

<Academic Medical Centers><Acceleration><Address><Administrative Supplement><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Body Tissues><Brain><Brain Nervous System><Clinic><Clinical><Cohort Studies><Collaborations><Collection><Colon><Complement><Complement Proteins><Concurrent Studies><Data><Data Management Core><Data Set><Deglutition><Deglutition Disorders><Dermatologic biopsy><Development><Disease Progression><Dysfunction><Dysphagia><Encephalon><Ensure><Fostering><Functional disorder><Funding><General Hospitals><Goals><Grant><Household><Immune response><Individual><Infrastructure><Intestinal><Intestines><Investments><Link><Manometry><Manometry Biochemistry><Massachusetts><Measures><Medical><Modeling><NAC precursor><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Neurologic><Neurological><Outcome><Outcome Measure><PARK1 protein><PARK4 protein><Paralysis Agitans><Parents><Parkinson><Parkinson Disease><Pathogenesis><Pathology><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Peripheral><Phase><Phenotype><Physiologic><Physiological><Physiopathology><Primary Parkinsonism><Prognosis><Protocol><Protocols documentation><Role><SNCA><SNCA protein><Sample Size><Sampling><Severity of illness><Site><South Carolina><Swallowing><Swallowing Disorders><Symptoms><Testing><Time><Tissues><United States National Institutes of Health><Universities><University Medical Centers><Work><a-syn><a-synuclein><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><bio-markers><biologic marker><biological specimen repository><biomarker><biosample repository><biospecimen bank><biospecimen repository><bowel><cohort><complementation><cutaneous biopsy><data management and coordinating center><data management center><depository><design><designing><developmental><diagnostic tool><disease diagnostic><disease severity><gastrointestinal><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><host response><immune system response><immunoresponse><improved><intestinal barrier><intestinal mucosal barrier><measurable outcome><metabolism measurement><metabolomics><metabonomics><microbial consortia><microbial flora><microbiome><microbiota><microbiota-gut-brain axis><microbiota-gut-brain interactions><microbiota-gut-brain signaling><microflora><multispecies consortia><non A-beta component of AD amyloid><non A4 component of amyloid precursor><novel><outcome measurement><parent><parent award><parent project><pathophysiology><patient oriented outcomes><recruit><repository><skin biopsy><social role><specimen bank><specimen repository><therapeutic target><α synuclein gene><α-syn><α-synuclein>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALI KESHAVARZIAN

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$214,082
FY 2025

Project Title

The Bidirectional Gut-Microbiota-Brain Axis in Parkinson’s disease: integrating mechanistic biomarkers of disease severity and progression

Grant Number:

3U01DK140923-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT This Administrative Supplement Request to U01 DK140923 at Rush University Medical Center (RUMC) / Medical University of South Carolina (MUSC) will significantly enhance the Gut Brain Parkinson's Disease Consortium (GBPDC) by integrating additional crucial gastrointestinal an...

Research Terms

<Academic Medical Centers><Acceleration><Address><Administrative Supplement><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Body Tissues><Brain><Brain Nervous System><Clinic><Clinical><Cohort Studies><Collaborations><Collection><Colon><Complement><Complement Proteins><Concurrent Studies><Data><Data Management Core><Data Set><Deglutition><Deglutition Disorders><Dermatologic biopsy><Development><Disease Progression><Dysfunction><Dysphagia><Encephalon><Ensure><Fostering><Functional disorder><Funding><General Hospitals><Goals><Grant><Household><Immune response><Individual><Infrastructure><Intestinal><Intestines><Investments><Link><Manometry><Manometry Biochemistry><Massachusetts><Measures><Medical><Modeling><NAC precursor><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Neurologic><Neurological><Outcome><Outcome Measure><PARK1 protein><PARK4 protein><Paralysis Agitans><Parents><Parkinson><Parkinson Disease><Pathogenesis><Pathology><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Peripheral><Phase><Phenotype><Physiologic><Physiological><Physiopathology><Primary Parkinsonism><Prognosis><Protocol><Protocols documentation><Role><SNCA><SNCA protein><Sample Size><Sampling><Severity of illness><Site><South Carolina><Swallowing><Swallowing Disorders><Symptoms><Testing><Time><Tissues><United States National Institutes of Health><Universities><University Medical Centers><Work><a-syn><a-synuclein><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><bio-markers><biologic marker><biological specimen repository><biomarker><biosample repository><biospecimen bank><biospecimen repository><bowel><cohort><complementation><cutaneous biopsy><data management and coordinating center><data management center><depository><design><designing><developmental><diagnostic tool><disease diagnostic><disease severity><gastrointestinal><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><host response><immune system response><immunoresponse><improved><intestinal barrier><intestinal mucosal barrier><measurable outcome><metabolism measurement><metabolomics><metabonomics><microbial consortia><microbial flora><microbiome><microbiota><microbiota-gut-brain axis><microbiota-gut-brain interactions><microbiota-gut-brain signaling><microflora><multispecies consortia><non A-beta component of AD amyloid><non A4 component of amyloid precursor><novel><outcome measurement><parent><parent award><parent project><pathophysiology><patient oriented outcomes><recruit><repository><skin biopsy><social role><specimen bank><specimen repository><therapeutic target><α synuclein gene><α-syn><α-synuclein>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amol Sharma

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$214,082
FY 2025

Project Title

The Bidirectional Gut-Microbiota-Brain Axis in Parkinson’s disease: integrating mechanistic biomarkers of disease severity and progression

Grant Number:

3U01DK140923-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT This Administrative Supplement Request to U01 DK140923 at Rush University Medical Center (RUMC) / Medical University of South Carolina (MUSC) will significantly enhance the Gut Brain Parkinson's Disease Consortium (GBPDC) by integrating additional crucial gastrointestinal an...

Research Terms

<Academic Medical Centers><Acceleration><Address><Administrative Supplement><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Body Tissues><Brain><Brain Nervous System><Clinic><Clinical><Cohort Studies><Collaborations><Collection><Colon><Complement><Complement Proteins><Concurrent Studies><Data><Data Management Core><Data Set><Deglutition><Deglutition Disorders><Dermatologic biopsy><Development><Disease Progression><Dysfunction><Dysphagia><Encephalon><Ensure><Fostering><Functional disorder><Funding><General Hospitals><Goals><Grant><Household><Immune response><Individual><Infrastructure><Intestinal><Intestines><Investments><Link><Manometry><Manometry Biochemistry><Massachusetts><Measures><Medical><Modeling><NAC precursor><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Neurologic><Neurological><Outcome><Outcome Measure><PARK1 protein><PARK4 protein><Paralysis Agitans><Parents><Parkinson><Parkinson Disease><Pathogenesis><Pathology><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Peripheral><Phase><Phenotype><Physiologic><Physiological><Physiopathology><Primary Parkinsonism><Prognosis><Protocol><Protocols documentation><Role><SNCA><SNCA protein><Sample Size><Sampling><Severity of illness><Site><South Carolina><Swallowing><Swallowing Disorders><Symptoms><Testing><Time><Tissues><United States National Institutes of Health><Universities><University Medical Centers><Work><a-syn><a-synuclein><alpha synuclein><alpha synuclein gene><alphaSP22><asyn><bio-markers><biologic marker><biological specimen repository><biomarker><biosample repository><biospecimen bank><biospecimen repository><bowel><cohort><complementation><cutaneous biopsy><data management and coordinating center><data management center><depository><design><designing><developmental><diagnostic tool><disease diagnostic><disease severity><gastrointestinal><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><host response><immune system response><immunoresponse><improved><intestinal barrier><intestinal mucosal barrier><measurable outcome><metabolism measurement><metabolomics><metabonomics><microbial consortia><microbial flora><microbiome><microbiota><microbiota-gut-brain axis><microbiota-gut-brain interactions><microbiota-gut-brain signaling><microflora><multispecies consortia><non A-beta component of AD amyloid><non A4 component of amyloid precursor><novel><outcome measurement><parent><parent award><parent project><pathophysiology><patient oriented outcomes><recruit><repository><skin biopsy><social role><specimen bank><specimen repository><therapeutic target><α synuclein gene><α-syn><α-synuclein>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael Suttie

UNIVERSITY OF OXFORD, UNITED KINGDOM

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$207,399
FY 2025

Project Title

Defining Translational Approaches for the Image-based Detection of Prenatal Alcohol Exposure

Grant Number:

5U01AA014809-22

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2022

End Date:

4/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

As a constituent component of CIFASD5, this project will focus on improving the identification of individuals with prenatal alcohol exposure (PAE), across the lifespan, with the primary goal of translation for clinical application. We target two main categories outlined in the Request for Applicatio...

Research Terms

<0-11 years old><21+ years old><3-D><3-D Images><3-D Imaging><3-D image><3-Dimensional><3D><3D image><3D images><3D imaging><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Age><Agreement><Alcohol Chemical Class><Alcohols><Assessment instrument><Assessment tool><Automation><Brain><Brain Nervous System><Categories><Cell Phone><Cellular Phone><Cellular Telephone><Cephalic><Child><Child Youth><Children (0-21)><Clinic><Clinical><Clinical assessments><Cognitive><Cognitive Discrimination><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Computer software><Corpus Callosum><Corpus Callosums><Cranial><Data><Data Management Resources><Data Management System><Data Set><Devices><Diagnosis><Differences between sexes><Differs between sexes><Discrimination><Disturbance in cognition><Echography><Echotomography><Elements><Encephalon><Ensure><Ethnic Origin><Ethnicity><Evaluation><Eye Socket><FASD><Face><Feedback><Fetal Alcohol Exposure><Fetal Alcohol Spectrum Disorder><Fetal Alcohol Syndrome><Fetal ETOH Exposure><Fetal Ethanol Exposure><Fetal alcohol effects><Goals><Hypertelorism><Hypertelorism of Orbit><Image><Image Analyses><Image Analysis><Imaging Device><Imaging Instrument><Imaging Tool><Impaired cognition><In Utero Alcohol Exposure><In Utero ETOH Exposure><In Utero Ethanol Exposure><Individual><Infant><Inferior Maxillary Bone><Intervention><Intervention Studies><Leanness><Length><Life><Lip><Lip structure><Literature><MRI Scans><Machine Learning><Magnetic Resonance Imaging Scan><Mandible><Measurement><Medical Ultrasound><Methodology><Methods><Micrognathism><Mobile Phones><Morphology><NIH RFA><Neonatal><Neurocognitive><Ocular orbit><On-Line Systems><Online Systems><Orbital Cavity><Orbital separation excessive><Outcome><Output><Parents><Population><Prenatal Alcohol Exposure><Prenatal ETOH Exposure><Prenatal Ethanol Exposure><R24><Request for Applications><Research><Research Resources><Resources><Screening procedure><Secondary to><Sensitivity and Specificity><Sex Differences><Sexual differences><Shapes><Smoking><Software><Surface><System><Tablets><Techniques><Technology><Testing><Thinness><Three-Dimensional Image><Three-Dimensional Imaging><Time><Training><Translating><Trees><Ultrasonic Imaging><Ultrasonogram><Ultrasonography><Ultrasound Diagnosis><Ultrasound Medical Imaging><Ultrasound Test><Validation><Variant><Variation><Work><adulthood><ages><alcohol consumption during pregnancy><alcohol during pregnancy><alcohol exposed><alcohol exposure><alcohol intake during pregnancy><alcohol-exposed pregnancy><alcoholic embryopathy><brain morphology><brain shape><clinical applicability><clinical application><clinical diagnosis><cloud platform><cloud server><cognitive assessment><cognitive dysfunction><cognitive loss><cognitive testing><comparative><cost><deep learning><deep learning method><deep learning strategy><diagnostic ultrasound><drinking alcohol during pregnancy><embryofetal alcohol syndrome><embryopathia alcoholica><ethanol consumption during pregnancy><ethanol exposed><ethanol exposure><experience><exposed to alcohol><exposed to alcohol prenatally><exposed to ethanol><exposure to alcohol><exposure to ethanol><faces><facial><gestation ETOH exposure><gestation alcohol exposure><gestation ethanol exposure><gestational ethanol exposure><iPhone><image evaluation><image interpretation><imaging><imaging detection><imaging-based detection><imaging-based disease detection><improved><intervention research><interventional research><interventional study><interventions research><juvenile><juvenile human><kids><life span><lifespan><machine based learning><mandibular><micrognathia><midfacial hypoplasia><multiple substance use><multisubstance use><neural><neurocognitive test><offspring><online computer><orbit><parent><poly substance use><polysubstance use><pregnancy ETOH exposure><pregnancy alcohol exposure><pregnancy ethanol exposure><prenatal alcohol consumption><prenatal alcohol effect><prenatal alcohol use><prenatal drinking><prenatally alcohol exposed><prenatally exposed to alcohol><recruit><screening><screening tools><screenings><sex><sex based differences><sex dimorphism><sex-dependent differences><sex-related differences><sex-specific differences><sexual dimorphism><sexually dimorphic><skills><smart phone><smartphone><sonogram><sonography><sound measurement><three dimensional><tool><trait><translation strategy><translational approach><translational goal><translational mission><translational strategy><ultrasound><ultrasound imaging><ultrasound scanning><validations><web based><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ADAM L. BOXER

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$174,552
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S1

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bradley F Boeve

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$174,552
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S1

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HOWARD J ROSEN

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$174,552
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S1

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Brad C Astor

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$168,000
FY 2025

Project Title

1/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical Center

Grant Number:

5U01DK116092-08

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT Recipients of a kidney transplant from an African-American deceased donor have worse outcomes than their counterparts receiving an organ from a European-American deceased donor. In addition, kidney transplants from deceased donors with two apolipoprotein L1 gene (APOL1) high...

Research Terms

<Academic Medical Centers><Acceleration><Active Follow-up><Acute><Address><African American><African ancestry><African descent><Afro American><Afroamerican><Albumins><Allografting><American><Antibodies><Apolipoproteins><Bacterial Infections><Blood><Blood Reticuloendothelial System><Blood Serum><Caring><Clinic><Clinical Data><Consent><Cost Savings><Counseling><Creatinine><DNA><Data><Deoxyribonucleic Acid><Disparities><Disparity><Donor person><Education><Educational aspects><Enrollment><Ensure><Environmental Factor><Environmental Risk Factor><European><Evaluation><Face><Failure><Gene variant><Genes><Genetic><Genetic predisposing factor><Genotype><Geography><Graft Survival><HL-A Antigens><HLA Antigens><Human Leukocyte Antigens><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Injury><Intervention><Iowa><Kidney><Kidney Failure><Kidney Grafting><Kidney Insufficiency><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Lesion><Leukocyte Antigens><Living Donors><Long-term Follow-up><Measures><Medical><Minnesota><Monitor><NIH><National Institutes of Health><Nebraska><Organ><Outcome><Outcome Study><Participant><Pattern><Phase><Phenotype><Policies><Prevalence><Proteinuria><Public Health><QOL><Quality of life><Recurrent disease><Registries><Relapsed Disease><Relative Risks><Renal Failure><Renal Grafting><Renal Insufficiency><Renal Transplantation><Renal Transplants><Renal function><Reporting><Research><Risk><Risk-associated variant><Role><Safety><Serum><Time><Transplant Recipients><Transplantation><UNOS><United Network for Organ Sharing><United States National Institutes of Health><Universities><University Medical Centers><Urine><Variant><Variation><Viral Diseases><Virus Diseases><Wisconsin><active followup><allelic variant><bacteria infection><bacterial disease><base><bases><clinical center><cohort><deceased donor><deceased organ donors><differences due to race><differences in race><differs by race><differs in race><enroll><environmental risk><ethnic difference><ethnicity difference><faces><facial><follow up><follow-up><followed up><followup><gene interaction><genetic risk factor><genetic variant><genomic variant><graft failure><graft function><high risk><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><inherited factor><injuries><kidney biopsy><kidney function><kidney tx><live kidney donor><living kidney donor><long-term followup><novel><post-transplant><post-transplantation><posthumous donors><posthumous organ donor><posttransplant><posttransplantation><primary outcome><programs><prospective><race based differences><race differences><race related differences><racial difference><racially different><recruit><renal><renal biopsy><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><secondary outcome><social role><transplant><transplant donor><transplant patient><viral infection><virus infection><virus-induced disease>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Benjamin Lebwohl

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$163,367
FY 2025

Project Title

Evaluation of Novel Technologies to Improve Clinical Management of Celiac Disease: The GLUTECH Trial

Grant Number:

3U01DK136523-03S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY The proposed project addresses the need for a rigorous trial to test the effectiveness of novel gluten detection technologies as an adjunct to telemedicine to manage celiac disease in adults. Celiac disease affects about 1% of the United States (U.S.) population and seroprevalence ha...

Research Terms

<21+ years old><7S Gamma Globulin><Active Follow-up><Address><Adherence><Adoption><Adult><Adult Human><Affect><Anemia><Anti-TG2><Anti-tTG><Antibodies><Antibodies to tissue transglutaminase><Antitissue transglutaminase antibodies><Anxiety><Autoantibodies><Autoantibodies to tissue transglutaminase><Awareness><Behavioral><Blood Serum><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 antigen><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Cancers><Cannot achieve a pregnancy><Celiac Disease><Celiac Sprue><Chemistry><Clinical><Clinical Management><Clinical Trials><Coeliac Disease><Communication><Complement><Complement Proteins><Consumption><Country><Detection><Diagnosis><Dietary quality><Dietitian><Difficulty conceiving><Digestive Diseases><Digestive System Diseases><Digestive System Disorders><Disease Management><Disorder Management><Eating Behavior><Effectiveness><Evaluation><Fatigue><Food><GI tract disorder><Gastroenterology><Gliadin><Glutelin><Gluten><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Gluten-free diet><Grant><Health><Health Care Professional><Health Professional><Height><Histology><Home><IgA><IgG><Illinois><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunoglobulin A><Immunoglobulin G><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Incidence><Individual><Infertility><Infrastructure><Intervention><Lack of Energy><Link><Lymphocyte Count><Lymphocyte Number><Malignant Neoplasms><Malignant Tumor><Massachusetts><Measures><Mediator><Mental Depression><Monitor><Morbidity><Morbidity - disease rate><Motivation><Mucosa><Mucosal Tissue><Mucous Membrane><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><New York><Newly Diagnosed><Non-tropical Sprue><Nontropical Sprue><Osteoporosis><Outcome><Outcome Study><Participant><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peptide antibodies><Peptides><Performance><Persons><Physicians><Pisum sativum><Population><QOL><Quality of life><Randomized><Randomized, Controlled Trials><Recommendation><Recovery><Regimen><SARS-CoV-2 antigen><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Sample Size><Sampling><Serology><Seroprevalences><Serum><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social support><Symptoms><Technology><Telemedicine><Tennessee><Testing><Tissue Transglutaminase Antibodies><Tissue transglutaminase IgA><Tissue transglutaminase autoantibodies><Total Lymphocyte Count><Translating><United States><Urine><Videoconferencing><Villus><acceptability and feasibility><active followup><adulthood><antigen based test><antigen test><assess effectiveness><autoimmune antibody><autoreactive antibody><clinical development><comparative cost effectiveness><compare cost><compare cost effectiveness><complementation><coronavirus disease 2019 antigen><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost comparison><cost effective><cost effectiveness><deamidation><depression><determine effectiveness><diet adherence><diet quality><dietary><dietary adherence><digestive disorder><digestive tract disease><effectiveness assessment><effectiveness evaluation><effectiveness testing><evaluate effectiveness><examine effectiveness><fertility cessation><fertility loss><follow up><follow-up><followed up><followup><gastrointestinal symptom><gastrointestinal tract disease><gastrointestinal tract disorder><homes><idiopathic steatorrhea><immunogenic><improved><infertile><intraepithelial><malignancy><meeting><meetings><mortality><neoplasm/cancer><new technology><novel><novel technologies><pandemic><pandemic disease><pathway><patient oriented outcomes><pea><portability><primary end point><primary endpoint><primary outcome><psychologic><psychological><randomisation><randomization><randomized control trial><randomly assigned><rapid testing><recruit><secondary outcome><self reactive antibody><sensor><severe acute respiratory syndrome coronavirus 2 antigen><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social><social support network><standard of care><tool><validation studies><video conferencing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Randi L. Wolf

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$163,367
FY 2025

Project Title

Evaluation of Novel Technologies to Improve Clinical Management of Celiac Disease: The GLUTECH Trial

Grant Number:

3U01DK136523-03S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY The proposed project addresses the need for a rigorous trial to test the effectiveness of novel gluten detection technologies as an adjunct to telemedicine to manage celiac disease in adults. Celiac disease affects about 1% of the United States (U.S.) population and seroprevalence ha...

Research Terms

<21+ years old><7S Gamma Globulin><Active Follow-up><Address><Adherence><Adoption><Adult><Adult Human><Affect><Anemia><Anti-TG2><Anti-tTG><Antibodies><Antibodies to tissue transglutaminase><Antitissue transglutaminase antibodies><Anxiety><Autoantibodies><Autoantibodies to tissue transglutaminase><Awareness><Behavioral><Blood Serum><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 antigen><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Cancers><Cannot achieve a pregnancy><Celiac Disease><Celiac Sprue><Chemistry><Clinical><Clinical Management><Clinical Trials><Coeliac Disease><Communication><Complement><Complement Proteins><Consumption><Country><Detection><Diagnosis><Dietary quality><Dietitian><Difficulty conceiving><Digestive Diseases><Digestive System Diseases><Digestive System Disorders><Disease Management><Disorder Management><Eating Behavior><Effectiveness><Evaluation><Fatigue><Food><GI tract disorder><Gastroenterology><Gliadin><Glutelin><Gluten><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Gluten-free diet><Grant><Health><Health Care Professional><Health Professional><Height><Histology><Home><IgA><IgG><Illinois><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunoglobulin A><Immunoglobulin G><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Incidence><Individual><Infertility><Infrastructure><Intervention><Lack of Energy><Link><Lymphocyte Count><Lymphocyte Number><Malignant Neoplasms><Malignant Tumor><Massachusetts><Measures><Mediator><Mental Depression><Monitor><Morbidity><Morbidity - disease rate><Motivation><Mucosa><Mucosal Tissue><Mucous Membrane><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><New York><Newly Diagnosed><Non-tropical Sprue><Nontropical Sprue><Osteoporosis><Outcome><Outcome Study><Participant><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peptide antibodies><Peptides><Performance><Persons><Physicians><Pisum sativum><Population><QOL><Quality of life><Randomized><Randomized, Controlled Trials><Recommendation><Recovery><Regimen><SARS-CoV-2 antigen><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Sample Size><Sampling><Serology><Seroprevalences><Serum><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social support><Symptoms><Technology><Telemedicine><Tennessee><Testing><Tissue Transglutaminase Antibodies><Tissue transglutaminase IgA><Tissue transglutaminase autoantibodies><Total Lymphocyte Count><Translating><United States><Urine><Videoconferencing><Villus><acceptability and feasibility><active followup><adulthood><antigen based test><antigen test><assess effectiveness><autoimmune antibody><autoreactive antibody><clinical development><comparative cost effectiveness><compare cost><compare cost effectiveness><complementation><coronavirus disease 2019 antigen><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost comparison><cost effective><cost effectiveness><deamidation><depression><determine effectiveness><diet adherence><diet quality><dietary><dietary adherence><digestive disorder><digestive tract disease><effectiveness assessment><effectiveness evaluation><effectiveness testing><evaluate effectiveness><examine effectiveness><fertility cessation><fertility loss><follow up><follow-up><followed up><followup><gastrointestinal symptom><gastrointestinal tract disease><gastrointestinal tract disorder><homes><idiopathic steatorrhea><immunogenic><improved><infertile><intraepithelial><malignancy><meeting><meetings><mortality><neoplasm/cancer><new technology><novel><novel technologies><pandemic><pandemic disease><pathway><patient oriented outcomes><pea><portability><primary end point><primary endpoint><primary outcome><psychologic><psychological><randomisation><randomization><randomized control trial><randomly assigned><rapid testing><recruit><secondary outcome><self reactive antibody><sensor><severe acute respiratory syndrome coronavirus 2 antigen><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social><social support network><standard of care><tool><validation studies><video conferencing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Thomas G Brott

MAYO CLINIC JACKSONVILLE, JACKSONVILLE, FL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$156,497
FY 2025

Project Title

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)

Grant Number:

3U01NS080168-12S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2014

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY The Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2, U01 NS080168) consists of two parallel randomized trials in patients with asymptomatic high- grade carotid artery stenosis. One trial compares Intensive Medical Management (IMM) plu...

Research Terms

<Active Follow-up><Address><Administrative Supplement><Award><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Carotid Artery Narrowing><Carotid Artery Stenosis><Carotid Endarterectomy><Carotid Stenosis><Carotid stent><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Data Coordinating Center><Data Coordination Center><Data Set><Devices><Documentation><Endarterectomy><Enrollment><Ensure><Forensic Medicine><Forensics><Frequencies><Funding><Goals><Grant><IRB><IRBs><Informed Consent><Institutional Review Boards><International><Investigators><Knowledge><Medical><Modernization><Monitor><NIH><NINDS><National Institute of Neurological Diseases and Stroke><National Institute of Neurological Disorders and Stroke><National Institutes of Health><Outsourcing><Patients><Peer Review><Persons><Play><Policies><Process><Quality Control><Randomization trial><Reporting><Research Personnel><Researchers><Risk><Role><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Sample Size><Science><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Site><Source><Stents><Study Subject><Survey Instrument><Surveys><System><Travel><United States National Institutes of Health><Visit><active followup><carotid artery stent><carotid stenting><clinical research site><clinical site><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost effective><dashboard><data quality><data quality/integrity><data standardization><data standards><design><designing><enroll><follow up><follow-up><followed up><followup><human subject><meeting><meetings><patient safety><preference><primary end point><primary endpoint><randomized trial><remote monitoring><remote visit><revascularization><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social role><trial comparing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JAMES F MESCHIA

MAYO CLINIC JACKSONVILLE, JACKSONVILLE, FL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$156,497
FY 2025

Project Title

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)

Grant Number:

3U01NS080168-12S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2014

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY The Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2, U01 NS080168) consists of two parallel randomized trials in patients with asymptomatic high- grade carotid artery stenosis. One trial compares Intensive Medical Management (IMM) plu...

Research Terms

<Active Follow-up><Address><Administrative Supplement><Award><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Carotid Artery Narrowing><Carotid Artery Stenosis><Carotid Endarterectomy><Carotid Stenosis><Carotid stent><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Data Coordinating Center><Data Coordination Center><Data Set><Devices><Documentation><Endarterectomy><Enrollment><Ensure><Forensic Medicine><Forensics><Frequencies><Funding><Goals><Grant><IRB><IRBs><Informed Consent><Institutional Review Boards><International><Investigators><Knowledge><Medical><Modernization><Monitor><NIH><NINDS><National Institute of Neurological Diseases and Stroke><National Institute of Neurological Disorders and Stroke><National Institutes of Health><Outsourcing><Patients><Peer Review><Persons><Play><Policies><Process><Quality Control><Randomization trial><Reporting><Research Personnel><Researchers><Risk><Role><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Sample Size><Science><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Site><Source><Stents><Study Subject><Survey Instrument><Surveys><System><Travel><United States National Institutes of Health><Visit><active followup><carotid artery stent><carotid stenting><clinical research site><clinical site><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost effective><dashboard><data quality><data quality/integrity><data standardization><data standards><design><designing><enroll><follow up><follow-up><followed up><followup><human subject><meeting><meetings><patient safety><preference><primary end point><primary endpoint><randomized trial><remote monitoring><remote visit><revascularization><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social role><trial comparing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Thimmasettappa Thippeswamy

IOWA STATE UNIVERSITY, AMES, IA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$146,426
FY 2025

Project Title

Investigating the efficacy and mechanistic pathways of saracatinib, a medical countermeasure, in a pediatric rat DFP model

Grant Number:

3U01NS117284-05S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2021

End Date:

7/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Abstract The organophosphate nerve agent (OPNA) attacks in Tokyo, Syria, Malaysia, and England prove the real threat of OPNAs. Acute exposure to OPNA impacts human health globally, and we lack treatment for survivors. Until recently, preventing acute death due to OPNA exposure was a priority. Howeve...

Research Terms

<21+ years old><AD dementia><Acquired brain injury><Acute><Address><Administrative Supplement><Adult><Adult Human><After Care><After-Treatment><Aftercare><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Animal Euthanasia><Animal Mercy Killing><Animal Model><Animal Models and Related Studies><Animals><Annual Reports><Anticholinesterase Agents><Anticholinesterase Drugs><Anticholinesterases><Assay><Atropine><Behavioral><Bioassay><Biological Assay><Blood><Blood Reticuloendothelial System><Blood Serum><Brain><Brain Injuries><Brain Nervous System><Cancers><Cerebrospinal Fluid><Cessation of life><Chemicals><Chemotactic Cytokines><Childhood><Cholinesterase Inhibitors><Chronic><Clinical Data><Clinical Research><Clinical Study><Clinical Trials><Cognitive><Common Rat Strains><Data><Data Set><Death><Development><Diet><Disease><Disorder><Dose><Drug Kinetics><Drugs><Dysfunction><EDRF Synthase><Encephalon><Endothelium-Derived Growth Factor Synthase><England><Epilepsy><Epileptic Seizures><Epileptics><Euthanasia><Exposure to><FYN Protein><Federation of Malaya><Functional disorder><Funding><Future><Generalized Status Epilepticus><Goals><Guanylyl Cyclase-Activating Factor Synthase><Homologous Chemotactic Cytokines><Hospital Admission><Hospitalization><Hospitals><Hour><Human><INOS><Immunoblotting><Impairment><Inducible Nitric Oxide Synthase><Intercrines><Investigational Drugs><Investigational New Drugs><Kinases><L-Serine><L-Threonine><Long-Term Effects><Longitudinal Studies><Macrophage Nitric Oxide Synthase><Malay Federation><Malaya><Malaysia><Malignant Neoplasms><Malignant Tumor><Medication><Mercy Killing><Midazolam><Modeling><Modern Man><Modification><Molecular><Motor><NO Synthase><NOS2><NOS2A><NOS2A gene><NOS2A, Inducible, Hepatocyte><Nerve Degeneration><Neurologic><Neurologic Dysfunctions><Neurological><Neuron Degeneration><Neuroprotectants><Neuroprotective Agents><Neuroprotective Drugs><Nitric Oxide Synthase><Nitric Oxide Synthase 2A><Nitric Oxide Synthetase Inhibitor><Nitric-Oxide Synthetase><Oral><Organophosphates><Outcome><Ownership><PTK Inhibitors><Pathway interactions><Pharmaceutical Preparations><Pharmacokinetics><Phosphoproteins><Phosphorylation><Phosphotransferase Gene><Phosphotransferases><Phosphotyrosine><Physiopathology><Pre IND FDA meeting><Pre-IND mtg><Preclinical data><Primary Senile Degenerative Dementia><Process><Protein Phosphorylation><Protein Tyrosine Kinase Inhibitors><Proteins><Proto-Oncogene Proteins c-fyn><Publications><Rat><Rats Mammals><Rattus><Research><SIS cytokines><Sampling><Sarin><Scientific Publication><Secure><Seizure Disorder><Seizures><Serine><Serum><Soman><Status Epilepticus><Survivors><Symptoms><Syria><Syrian Arab Republic><TK Inhibitors><Testing><Threonine><Time><Tokyo><Transphosphorylases><Tyrosine><Tyrosine Kinase Inhibitor><Tyrosine-O-phosphate><Western Blotting><Western Immunoblotting><adulthood><behavior outcome><behavior test><behavioral outcome><behavioral test><brain damage><brain tissue><brain-injured><c-fyn protein><cerebral spinal fluid><chemoattractant cytokine><chemokine><cholinergic><co-morbid><co-morbidity><comorbidity><conventional therapy><conventional treatment><cytokine><developmental><diet control><dietary control><diets><differential expression><differentially expressed><dl-Hyoscyamine><drug detection><drug testing><drug/agent><epilepsia><epileptogenic><experiment><experimental research><experimental study><experiments><fyn tyrosine kinase><global health><inhibitor><insight><interest><kainate><kinase inhibitor><long-term study><longitudinal outcome studies><malignancy><medical countermeasure><meeting><meetings><model of animal><neoplasm/cancer><nerve agent><neural degeneration><neural inflammation><neurodegeneration><neurodegenerative><neuroinflammation><neuroinflammatory><neurological degeneration><neurological dysfunction><neuron toxicity><neuronal degeneration><neuronal toxicity><neuroprotection><neuroprotective><neurotoxicity><nitric oxide synthase inhibitor><novel><open innovation><pathophysiology><pathway><pediatric><phospho-proteomics><phosphoproteomics><post treatment><postnatal><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><pre-clinical study><preclinical findings><preclinical information><preclinical study><prevent><preventing><primary degenerative dementia><primary outcome><programs><protective effect><protein blotting><proto-oncogene protein c-syn><psychologic><psychological><senile dementia of the Alzheimer type><sex><spinal fluid><src Kinases><src Protein-Tyrosine Kinases><src Tyrosine Kinases><src-Family Kinases><src-Family Tyrosine Kinases><stressor><transcriptional differences>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Leticia Maria MARQUEZ-MAGANA

SAN FRANCISCO STATE UNIVERSITY, SAN FRANCISCO, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$125,927
FY 2025

Project Title

Examining Anti-Racist Healing in Nature to Protect Telomeres of Transitional Age BIPOC for Health Equity.

Grant Number:

3U01ES036366-03S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Summary: The overall goal of this diversity supplement to the NIEHS U01 Reclaiming Nature parent grant is to provide Dr. Ekland Abdiwahab, an African-American social epidemiologist, with training in biobehavioral research methods, career development, and mentorship to support her transition into an ...

Research Terms

<21+ years old><Acceleration><Address><Adult><Adult Human><African American><Afro American><Afroamerican><Age><BIPOC><Black, Indigenous, People of Color><Buffers><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Career Mobility><Cell Aging><Cell Senescence><Cellular Aging><Cellular Senescence><Cessation of life><Chronic><Chronic Disease><Chronic Illness><Cognitive Discrimination><Collaborations><Color><Communities><Conscious><Consciousness><Death><Decrease health disparities><Development><Discrimination><Distress><Doctor of Philosophy><Economics><Educational workshop><Emotional well being><Ensure><Epidemiologist><Event><Exposure to><Federal Government><Feels well><Funding><Goals><Green space><Group Meetings><Health Inequity><Health disparity mitigation><Health disparity reduction><Individuals from minority><Individuals of minority><Inequalities in Health><Inequities in Health><Intervention><Investigators><K-Awards><K-Series Research Career Programs><Knowledge><Length><Life><Lower health disparities><Mentorship><Methodology><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Mitigate health disparities><NIEHS><National Government><National Institute of Environmental Health Sciences><Nature><Normal mental condition><Normal mental state><Normal psyche><Parents><Ph.D.><PhD><Physical activity><Policies><Preventative measure><Preventive measure><Psychological Well Being><Public Health><Publications><Reduce health disparities><Replicative Senescence><Reporting><Research><Research Career Program><Research Methodology><Research Methods><Research Personnel><Research Priority><Research Resources><Researchers><Resources><Role><Scientific Publication><Sense of well-being><Social Psychology><Stress><Students><System><Testing><Training><United States><Well in self><Work><Workshop><Youth><Youth 10-21><adulthood><ages><anti-racism><anti-racist><biobehavior><biobehavioral><cancer disparity><cancer health disparity><cancer-related health disparity><career><career advancement><career development><career transition><chronic disorder><community engagement><coping><cost><cost effective><culturally adapted intervention><culturally appropriate intervention><culturally centered intervention><culturally focused intervention><culturally informed intervention><culturally responsive intervention><culturally tailored intervention><design><designing><developmental><disparities in race><disparity due to race><disparity in cancer><disparity in health><economic><emotional wellbeing><emotional wellness><engagement with communities><experience><experienced discrimination><greenspace><group of color><healing><health disparity><health equity><health inequalities><individual of color><inequality due to race><inequity due to race><insight><meeting><meetings><mental well-being><mental wellbeing><mental wellness><parent><parent grant><people of color><perceived discrimination><perception of discrimination><person of color><population of color><prevent><preventing><psychological wellbeing><psychological wellness><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><racism><replicative aging><research and methods><self wellness><self-reported discrimination><sense of wellbeing><social><social role><social stresses><social stressor><telomere><uptake><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Charlotte Tate

SAN FRANCISCO STATE UNIVERSITY, SAN FRANCISCO, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$125,927
FY 2025

Project Title

Examining Anti-Racist Healing in Nature to Protect Telomeres of Transitional Age BIPOC for Health Equity.

Grant Number:

3U01ES036366-03S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Summary: The overall goal of this diversity supplement to the NIEHS U01 Reclaiming Nature parent grant is to provide Dr. Ekland Abdiwahab, an African-American social epidemiologist, with training in biobehavioral research methods, career development, and mentorship to support her transition into an ...

Research Terms

<21+ years old><Acceleration><Address><Adult><Adult Human><African American><Afro American><Afroamerican><Age><BIPOC><Black, Indigenous, People of Color><Buffers><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Career Mobility><Cell Aging><Cell Senescence><Cellular Aging><Cellular Senescence><Cessation of life><Chronic><Chronic Disease><Chronic Illness><Cognitive Discrimination><Collaborations><Color><Communities><Conscious><Consciousness><Death><Decrease health disparities><Development><Discrimination><Distress><Doctor of Philosophy><Economics><Educational workshop><Emotional well being><Ensure><Epidemiologist><Event><Exposure to><Federal Government><Feels well><Funding><Goals><Green space><Group Meetings><Health Inequity><Health disparity mitigation><Health disparity reduction><Individuals from minority><Individuals of minority><Inequalities in Health><Inequities in Health><Intervention><Investigators><K-Awards><K-Series Research Career Programs><Knowledge><Length><Life><Lower health disparities><Mentorship><Methodology><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Mitigate health disparities><NIEHS><National Government><National Institute of Environmental Health Sciences><Nature><Normal mental condition><Normal mental state><Normal psyche><Parents><Ph.D.><PhD><Physical activity><Policies><Preventative measure><Preventive measure><Psychological Well Being><Public Health><Publications><Reduce health disparities><Replicative Senescence><Reporting><Research><Research Career Program><Research Methodology><Research Methods><Research Personnel><Research Priority><Research Resources><Researchers><Resources><Role><Scientific Publication><Sense of well-being><Social Psychology><Stress><Students><System><Testing><Training><United States><Well in self><Work><Workshop><Youth><Youth 10-21><adulthood><ages><anti-racism><anti-racist><biobehavior><biobehavioral><cancer disparity><cancer health disparity><cancer-related health disparity><career><career advancement><career development><career transition><chronic disorder><community engagement><coping><cost><cost effective><culturally adapted intervention><culturally appropriate intervention><culturally centered intervention><culturally focused intervention><culturally informed intervention><culturally responsive intervention><culturally tailored intervention><design><designing><developmental><disparities in race><disparity due to race><disparity in cancer><disparity in health><economic><emotional wellbeing><emotional wellness><engagement with communities><experience><experienced discrimination><greenspace><group of color><healing><health disparity><health equity><health inequalities><individual of color><inequality due to race><inequity due to race><insight><meeting><meetings><mental well-being><mental wellbeing><mental wellness><parent><parent grant><people of color><perceived discrimination><perception of discrimination><person of color><population of color><prevent><preventing><psychological wellbeing><psychological wellness><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><racism><replicative aging><research and methods><self wellness><self-reported discrimination><sense of wellbeing><social><social role><social stresses><social stressor><telomere><uptake><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ADAM L. BOXER

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$123,012
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S3

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bradley F Boeve

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$123,012
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S3

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HOWARD J ROSEN

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$123,012
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S3

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CLAUDIA R0SE BAQUET

UNIVERSITY OF MARYLAND BALTIMORE, BALTIMORE, MD

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$100,000
FY 2025

Project Title

Racial and Ethnic Minority Acceleration for Health Equity Consortium U01

Grant Number:

3U01FD007982-02S4

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

FDA

Start Date:

6/1/2023

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT This proposal responds to FDA's OMHHE desire to accelerate efforts to address racial and ethnic minority and health equity through its REACH Consortium. This two-phase “health equity acceleration” U01 application is submitted to participate in the FDA OMHHE Health Equity Inn...

View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Doratha Armenthus Byrd

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$95,364
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jane C. Figueiredo

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$95,364
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Biljana Gigic

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$95,364
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DAVID SHIBATA

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$95,364
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Adetunji T Toriola

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$95,364
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CORNELIA M ULRICH

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$95,364
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Doratha Armenthus Byrd

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$91,144
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jane C. Figueiredo

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$91,144
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Biljana Gigic

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$91,144
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DAVID SHIBATA

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$91,144
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Adetunji T Toriola

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$91,144
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CORNELIA M ULRICH

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$91,144
FY 2025

Project Title

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study

Grant Number:

3U01CA206110-10S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY. Colorectal cancer (CRC) is the second most common cancer among men and women in the U.S., leading to over 50,000 deaths per year. Research aimed at reducing CRC’s high burden, discovering/validating novel biomarkers associated with prognosis, addressing the growing epidemic of early...

Research Terms

<Active Follow-up><Address><Behavioral><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Cancer Prognosis><Cancer Survivorship><Cancers><Cessation of life><Clinical><Clinical Data><Cohort Studies><Collaborations><Collection><Colorectal Cancer><Communities><Concurrent Studies><Data><Data Banks><Data Reporting><Databanks><Death><Decision Making><Development><Diagnosis><Enrollment><Epidemic><Epidemiological data><Epidemiology data><Feces><Funding><GI microbiome><Geography><Goals><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Medical><Medical Records><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Newly Diagnosed><Outcome><Paper><Participant><Patient Outcomes Assessments><Patient Participation><Patient Recruitments><Patient Reported Measures><Patient Reported Outcomes><Patient Self-Report><Patients><Phase><Population><Prognosis><Protocol><Protocols documentation><Publishing><Questionnaires><Rectal Cancer><Rectal Carcinoma><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Science><Self-Report><Site><Standardization><Time><Tissue Sample><Tumor Tissue><Urine><Woman><active followup><anti-cancer research><bio-markers><biobank><biologic marker><biomarker><biorepository><blood-based biomarker><blood-based marker><cancer registry><cancer research><cancer resource><cohort><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><community advisory board><community advisory committee><community advisory panel><data depository><data harmonization><data repository><data representation><data representations><data set repository><data sharing><data warehouse><dataset repository><design><designing><developmental><digestive tract microbiome><early colo-rectal cancer><early colorectal cancer><early onset colo-rectal cancer><early onset colorectal cancer><enroll><enteric microbiome><epidemiologic data><experience><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><harmonized data><improved><indexing><innovate><innovation><innovative><interest><intestinal biome><intestinal microbiome><malignancy><men><microbiome><neoplasm registry><neoplasm resource><neoplasm/cancer><new drug target><new drug treatments><new druggable target><new drugs><new marker><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel biomarker><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel marker><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><participant engagement><participant recruitment><patient engagement><prospective><recruit><sample collection><specimen collection><stool><stool sample><stool specimen><survivorship><translational study><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ADAM L. BOXER

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$89,338
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S4

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bradley F Boeve

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$89,338
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S4

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HOWARD J ROSEN

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$89,338
FY 2025

Project Title

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)

Grant Number:

3U19AG063911-06S4

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2019

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT – ALLFTD2: OVERALL SECTION Frontotemporal lobar degeneration (FTLD) is an overarching term for a group of neurodegenerative disorders associated with the accumulation of toxic protein aggregates in the CNS, most commonly comprised of one of two major proteins—microtubule associated protein ...

Research Terms

<AD dementia><AD related dementia><ADRD><Abbreviations><Accuracy of Diagnosis><Achievement><Achievement Attainment><Address><Affect><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Applications Grants><Autopsy><Behavioral><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><C9ORF72><Cerebrospinal Fluid><Clinical><Clinical Data><Clinical Trials><Clinical Trials Design><Cognitive><Collection><Communities><DNA mutation><DNA-Binding Proteins><Data><Data Collection><Degenerative Neurologic Disorders><Development><Disease><Disease Progression><Disorder><Enrollment><Evaluation><FTD dementia><FTLD><Familial disease><Family><Fostering><Frontal Temporal Dementia><Frontal Temporal Lobar Degeneration><Frontotemporal Dementia><Frontotemporal Lobar Degenerations><Frontotemporal variety lobar degeneration><Funding><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Grant Proposals><Hereditary><History><Image><Individual><Industry><Infrastructure><Inherited><Knowledge><Laboratories><MAPT gene><MAPT protein><MRI Scans><MT-bound tau><MTBT1><Magnetic Resonance Imaging Scan><Manuscripts><Measurement><Measures><Methodology><Methods><Microtubule-Associated Proteins><Molecular Weight><Motor><Mutate><Mutation><NIH><National Institutes of Health><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><North America><PC cell-derived growth factor><PCDGF><PGRN gene><PGRN protein><Participant><Patients><Persons><Phase><Preparation><Primary Senile Degenerative Dementia><Progranulin><Protocol><Protocols documentation><Publishing><Recommendation><Recording of previous events><Research><Sampling><Scanning><Symptoms><Technology Assessment><Testing><Time><Tissues><United States National Institutes of Health><ages><arm><bio-markers><biologic><biologic marker><biomarker><cerebral spinal fluid><chromosome 9 open reading frame 72><cohort><computer based prediction><data sharing><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depository><design><designing><developmental><diagnostic accuracy><effective therapy><effective treatment><enroll><familial disorder><front temporal dementia><frontal lobe dementia><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobe degeneration associated with dementia><gene product><genome mutation><granulin precursor><high risk><histories><imaging><improved><insoluble aggregate><kindred><meeting><meetings><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><neural imaging><neuro-imaging><neurodegenerative illness><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><patient advocacy group><phenotypic data><postmortem><predictive modeling><preparations><prevent><preventing><primary degenerative dementia><programs><progranulin gene><progranulin protein><protein aggregate><protein aggregation><remote assessment><remote evaluation><repository><sample collection><senile dementia of the Alzheimer type><specific biomarkers><specimen collection><spinal fluid><tau><tau Proteins><tau factor><tool><treatment trial><τ Proteins>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Oliver Fiehn

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$79,380
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LEE E. GOLDSTEIN

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$79,380
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rima F Kaddurah-Daouk

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$79,380
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Wishart

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$79,380
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

FRANCINE GRODSTEIN

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$78,972
FY 2025

Project Title

Mexican Teachers Cohort Study: Genetics and Cognitive Function

Grant Number:

3U01AG084547-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

This is a resubmission of a U01 application for the “Alzheimer’s Disease Sequencing Project (ADSP) Follow- Up Study 2.0: The Diverse Population Initiative” (PAR-21-212). The overall goals are to: (i) contribute nearly 20,000 GWAS and 5000 whole genome sequences to ADSP from participants of the “Estu...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD dementia><AD related dementia><ADRD><Active Follow-up><Address><Admixture><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Amerindian><Autopsy><Blood Sample><Blood specimen><Central American><Chicanas><Chicanos><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Collaborations><Complement><Complement Proteins><Concurrent Studies><DNA><Data><Dementia><Deoxyribonucleic Acid><Diagnosis><Disturbance in cognition><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Follow-Up Studies><Followup Studies><GWA study><GWAS><Genes><Genetic><Genetic Determinism><Genetic Diversity><Genetic Variation><Genome><Genomics><Genotype><Goals><Health><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Impaired cognition><Indigenous><Individual><Investigators><Length><Linkage Disequilibrium><Maps><Measures><Mexican><Mexican Americans><Mexico><Mitochondrial DNA><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Other Genetics><Participant><Pathologic><Pathway interactions><Pattern><Phenotype><Population><Population Heterogeneity><Primary Senile Degenerative Dementia><Process><Research><Research Personnel><Research Specimen><Research Support><Researchers><Resource Sharing><Sampling><Secondary to><South American><Specimen><Testing><Time><Universities><Variant><Variation><Woman><Women's cohort><above age 65><active followup><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><ancestry analysis><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><cognitive assessment><cognitive dysfunction><cognitive function><cognitive loss><cognitive testing><cohort><cohort in women><cohort on women><complementation><data harmonization><data hub><depository><design><designing><diverse populations><entire genome><ethnic subgroup><ethnicity group><experience><female cohort><follow up><follow-up><followed up><followup><full genome><genetic determinant><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><harmonized data><heterogeneous population><heteroplasmy><human old age (65+)><improved><men><mtDNA><necropsy><neuropathologic><neuropathological><neuropathology><novel><over 65 years><pathway><population diversity><postmortem><primary degenerative dementia><recruit><repository><screening><screenings><senile dementia of the Alzheimer type><sharing hub><social health determinants><teacher><telomere><trait><whole genome><whole genome association analysis><whole genome association study><younger age><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Martin Lajous

RUSH UNIVERSITY MEDICAL CENTER, CHICAGO, IL

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$78,972
FY 2025

Project Title

Mexican Teachers Cohort Study: Genetics and Cognitive Function

Grant Number:

3U01AG084547-02S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

This is a resubmission of a U01 application for the “Alzheimer’s Disease Sequencing Project (ADSP) Follow- Up Study 2.0: The Diverse Population Initiative” (PAR-21-212). The overall goals are to: (i) contribute nearly 20,000 GWAS and 5000 whole genome sequences to ADSP from participants of the “Estu...

Research Terms

<65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD dementia><AD related dementia><ADRD><Active Follow-up><Address><Admixture><Age><Aged 65 and Over><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Amerindian><Autopsy><Blood Sample><Blood specimen><Central American><Chicanas><Chicanos><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive aging><Cognitive decline><Cognitive function abnormal><Cohort Studies><Collaborations><Complement><Complement Proteins><Concurrent Studies><DNA><Data><Dementia><Deoxyribonucleic Acid><Diagnosis><Disturbance in cognition><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Follow-Up Studies><Followup Studies><GWA study><GWAS><Genes><Genetic><Genetic Determinism><Genetic Diversity><Genetic Variation><Genome><Genomics><Genotype><Goals><Health><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Impaired cognition><Indigenous><Individual><Investigators><Length><Linkage Disequilibrium><Maps><Measures><Mexican><Mexican Americans><Mexico><Mitochondrial DNA><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Other Genetics><Participant><Pathologic><Pathway interactions><Pattern><Phenotype><Population><Population Heterogeneity><Primary Senile Degenerative Dementia><Process><Research><Research Personnel><Research Specimen><Research Support><Researchers><Resource Sharing><Sampling><Secondary to><South American><Specimen><Testing><Time><Universities><Variant><Variation><Woman><Women's cohort><above age 65><active followup><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><ancestry analysis><causal allele><causal gene><causal mutation><causal variant><causative mutation><causative variant><cognitive assessment><cognitive dysfunction><cognitive function><cognitive loss><cognitive testing><cohort><cohort in women><cohort on women><complementation><data harmonization><data hub><depository><design><designing><diverse populations><entire genome><ethnic subgroup><ethnicity group><experience><female cohort><follow up><follow-up><followed up><followup><full genome><genetic determinant><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><harmonized data><heterogeneous population><heteroplasmy><human old age (65+)><improved><men><mtDNA><necropsy><neuropathologic><neuropathological><neuropathology><novel><over 65 years><pathway><population diversity><postmortem><primary degenerative dementia><recruit><repository><screening><screenings><senile dementia of the Alzheimer type><sharing hub><social health determinants><teacher><telomere><trait><whole genome><whole genome association analysis><whole genome association study><younger age><≥65 years>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Oliver Fiehn

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$55,842
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S3

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LEE E. GOLDSTEIN

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$55,842
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S3

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rima F Kaddurah-Daouk

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$55,842
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S3

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Wishart

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$55,842
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S3

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Peter Scott Heeger

CEDARS-SINAI MEDICAL CENTER, LOS ANGELES, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$50,000
FY 2025

Project Title

Assessment of Biomarker Guided CNI Substitution in Kidney Transplantation

Grant Number:

3U01AI170424-04S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2025

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Current standard of care for kidney transplant (KTx) recipients has only modestly improved long-term aggregate graft and/or patient survival, identifying a crucial unmet medical need. As the at-risk KTx population is heterogeneous, the currently employed and relatively homogeneous therapeutic approa...

Research Terms

<1, 2-Dehydrocortisone><3-D><3-Dimensional><3D><Active Follow-up><Acute><Address><Affect><Allografting><Biological Markers><Biopsy><Calcineurin antagonist><Calcineurin inhibitor><Canada><Cessation of life><Characteristics><Clinical><Clinical Trials><Death><Dehydrocortisone><Delta(1)-Cortisone><Deltacortisone><Deltadehydrocortisone><Enrollment><Ensure><Event><FDA approved><Failure><Future><Glomerular Filtration Rate><Goals><HLA testing><HLA typing><HLA-BR><HLA-BR Antigens><HLA-D-Related Antigens><HLA-DR><HLA-DR Antigens><HLA-MT><HLA-MT Antigens><Health><Human><Imaging Procedures><Imaging Technics><Imaging Techniques><Immune><Immune Markers><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunological><Immunologically><Immunologics><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Infrastructure><Infusion><Infusion procedures><Injury><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Life><Mediating><Medical><Metacortandracin><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><Morbidity - disease rate><Multi-center studies><Multi-center trial><Multicenter Studies><Multicenter Trials><Mycophenolic Acid><NIH><National Institutes of Health><Neurocognitive><Observation research><Observation study><Observational Study><Observational research><Outcome><Outcome Measure><Pathway interactions><Patient Outcomes Assessments><Patient Participation><Patient Reported Measures><Patient Reported Outcomes><Patients><Phenotype><Population><Prednisone><Prednisonum><Productivity><Prognostic Marker><Prospective Studies><Protocol><Protocols documentation><Randomized><Randomized, Controlled Trials><Renal Grafting><Renal Transplantation><Renal Transplants><Research Design><Retrospective Studies><Risk><Safety><Self Administered><Self Administration><Stratification><Study Type><T cell receptor repertoire sequencing><T cell receptor sequencing><T-Cells><T-Lymphocyte><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><Tacrolimus><Testing><Therapeutic><Time><Toxic effect><Toxicities><Transplant Recipients><Transplantation><United States National Institutes of Health><Work><active followup><alloimmunity><antibody rejection><antibody-mediated rejection><arm><bio-markers><biologic marker><biomarker><clinical care><cohort><delta-Cortisone><design><designing><donor antibodies><donor-specific antibody><enroll><evidence base><fibrogenesis><follow up><follow-up><followed up><followup><graft function><human leukocyte antigen testing><human leukocyte antigen typing><immune suppression><immune suppressive activity><immune suppressive function><immune-based biomarkers><immunological biomarkers><immunological markers><immunosuppressed><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><improved outcome><infusions><injuries><insight><instrument><isoimmunity><kidney allograft><kidney tx><measurable outcome><molecular profile><molecular signature><novel><outcome measurement><outcome prediction><pathway><peripheral blood><post-transplant><post-transplantation><posttransplant><posttransplantation><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><primary end point><primary endpoint><prognostic biomarker><prognostic indicator><prospective><prospective test><racial diversity><racially diverse><randomisation><randomization><randomized control trial><randomly assigned><renal allograft><risk stratification><secondary end point><secondary endpoint><specific biomarkers><standard of care><stratify risk><study design><subcutaneous><subdermal><success><three dimensional><thymus derived lymphocyte><transplant><transplant patient><vascular constriction><vasoconstriction>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PETER W NICKERSON

CEDARS-SINAI MEDICAL CENTER, LOS ANGELES, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$50,000
FY 2025

Project Title

Assessment of Biomarker Guided CNI Substitution in Kidney Transplantation

Grant Number:

3U01AI170424-04S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2025

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Current standard of care for kidney transplant (KTx) recipients has only modestly improved long-term aggregate graft and/or patient survival, identifying a crucial unmet medical need. As the at-risk KTx population is heterogeneous, the currently employed and relatively homogeneous therapeutic approa...

Research Terms

<1, 2-Dehydrocortisone><3-D><3-Dimensional><3D><Active Follow-up><Acute><Address><Affect><Allografting><Biological Markers><Biopsy><Calcineurin antagonist><Calcineurin inhibitor><Canada><Cessation of life><Characteristics><Clinical><Clinical Trials><Death><Dehydrocortisone><Delta(1)-Cortisone><Deltacortisone><Deltadehydrocortisone><Enrollment><Ensure><Event><FDA approved><Failure><Future><Glomerular Filtration Rate><Goals><HLA testing><HLA typing><HLA-BR><HLA-BR Antigens><HLA-D-Related Antigens><HLA-DR><HLA-DR Antigens><HLA-MT><HLA-MT Antigens><Health><Human><Imaging Procedures><Imaging Technics><Imaging Techniques><Immune><Immune Markers><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Markers><Immunological><Immunologically><Immunologics><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Infrastructure><Infusion><Infusion procedures><Injury><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Life><Mediating><Medical><Metacortandracin><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><Morbidity><Morbidity - disease rate><Multi-center studies><Multi-center trial><Multicenter Studies><Multicenter Trials><Mycophenolic Acid><NIH><National Institutes of Health><Neurocognitive><Observation research><Observation study><Observational Study><Observational research><Outcome><Outcome Measure><Pathway interactions><Patient Outcomes Assessments><Patient Participation><Patient Reported Measures><Patient Reported Outcomes><Patients><Phenotype><Population><Prednisone><Prednisonum><Productivity><Prognostic Marker><Prospective Studies><Protocol><Protocols documentation><Randomized><Randomized, Controlled Trials><Renal Grafting><Renal Transplantation><Renal Transplants><Research Design><Retrospective Studies><Risk><Safety><Self Administered><Self Administration><Stratification><Study Type><T cell receptor repertoire sequencing><T cell receptor sequencing><T-Cells><T-Lymphocyte><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><Tacrolimus><Testing><Therapeutic><Time><Toxic effect><Toxicities><Transplant Recipients><Transplantation><United States National Institutes of Health><Work><active followup><alloimmunity><antibody rejection><antibody-mediated rejection><arm><bio-markers><biologic marker><biomarker><clinical care><cohort><delta-Cortisone><design><designing><donor antibodies><donor-specific antibody><enroll><evidence base><fibrogenesis><follow up><follow-up><followed up><followup><graft function><human leukocyte antigen testing><human leukocyte antigen typing><immune suppression><immune suppressive activity><immune suppressive function><immune-based biomarkers><immunological biomarkers><immunological markers><immunosuppressed><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><improved outcome><infusions><injuries><insight><instrument><isoimmunity><kidney allograft><kidney tx><measurable outcome><molecular profile><molecular signature><novel><outcome measurement><outcome prediction><pathway><peripheral blood><post-transplant><post-transplantation><posttransplant><posttransplantation><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><primary end point><primary endpoint><prognostic biomarker><prognostic indicator><prospective><prospective test><racial diversity><racially diverse><randomisation><randomization><randomized control trial><randomly assigned><renal allograft><risk stratification><secondary end point><secondary endpoint><specific biomarkers><standard of care><stratify risk><study design><subcutaneous><subdermal><success><three dimensional><thymus derived lymphocyte><transplant><transplant patient><vascular constriction><vasoconstriction>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Martin Cadeiras

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$47,885
FY 2025

Project Title

A prospective multiethnic HFpEF cohort from California's Central Valley

Grant Number:

3U01HL160274-05S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT This is a new U01 application to establish a Clinical Center (CC) for a prospective multiethnic HFpEF cohort from California central valley for deep phenotyping analyses. The investigative team is diverse, multidisciplinary, and complementary with investigators from School of Medicine, Coll...

Research Terms

<Age><Agriculture><Area><Atrial Fibrillation><Auricular Fibrillation><Blood flow><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Catchment Area><Center for Translational Science Activities><Central Valley><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Classification><Clinic><Clinical><Clinical Research><Clinical Sciences><Clinical Study><Community Hospitals><Complex><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Country><Coupled><Data><Data Science><Data Set><Development><Diabetes Mellitus><Diastolic heart failure><Disease><Disorder><EFRAC><Ejection Fraction><Electronic Health Record><Engineering><Enrollment><Environmental Science><Event><Funding><Generalized Growth><Genomics><Growth><HF with preserved ejection fraction><HFpEF><Health Care Technology><Health Technology><Heart><Heart Vascular><Heart failure><Heterogeneity><Hypertension><Image><Incidence><Inflammation><Inflammatory><Investigators><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Learning><Machine Learning><Metabolic><Metabolic syndrome><Mining><Molecular><Molecular Analysis><Morbidity><Morbidity - disease rate><NIH><National Institutes of Health><Obesity><Organ><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Patients><Phase><Phenotype><Plug-in><Population><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Progressive Disease><Proteomics><Pulmonary Hypertension><QOL><Quality of life><Rad.-PET><Records><Research><Research Institute><Research Personnel><Researchers><Role><Source><Syndrome><Systematics><Testing><Text><Therapeutic><Tissue Growth><United States><United States National Institutes of Health><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adiposity><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging associated disease><aging associated disorders><aging population><aging related disease><aging related disorders><atherosclerotic coronary disease><biomedical referral center><cardiac failure><cardiovascular disorder><career development><chronic kidney disease><circulatory system><clinical center><co-morbid><co-morbidity><cohort><college><collegiate><community clinic><comorbidity><connectome><coronary arterial disease><corpulence><developmental><diabetes><discovery mining><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><diverse populations><electronic data><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><functional status><heart failure and reduced ejection fraction><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart failure with reduced ejection fraction><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><indexing><innovate><innovation><innovative><insight><internet portal><literature mining><literature searching><m-Health><mHealth><machine based learning><medical college><medical schools><metabolism measurement><metabolomics><metabonomics><microbiome><minority communities><mobile health><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mortality><multi-ethnic><multidisciplinary><multiethnic><multiomics><multiple omics><next generation><novel><on-line portal><online portal><ontogeny><panomics><participant engagement><participant enrollment><patient engagement><patient enrollment><patient population><phenomics><phrases><population aging><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><preserved ejection fraction heart failure><programs><prospective><protocol development><recruit><referral center><remote monitoring><school of medicine><sex><skill acquisition><skill development><social role><text mining><text searching><translational research center><translational sciences center><web portal><web-based portal>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nipavan Chiamvimonvat

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$47,885
FY 2025

Project Title

A prospective multiethnic HFpEF cohort from California's Central Valley

Grant Number:

3U01HL160274-05S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT This is a new U01 application to establish a Clinical Center (CC) for a prospective multiethnic HFpEF cohort from California central valley for deep phenotyping analyses. The investigative team is diverse, multidisciplinary, and complementary with investigators from School of Medicine, Coll...

Research Terms

<Age><Agriculture><Area><Atrial Fibrillation><Auricular Fibrillation><Blood flow><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Catchment Area><Center for Translational Science Activities><Central Valley><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Classification><Clinic><Clinical><Clinical Research><Clinical Sciences><Clinical Study><Community Hospitals><Complex><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Country><Coupled><Data><Data Science><Data Set><Development><Diabetes Mellitus><Diastolic heart failure><Disease><Disorder><EFRAC><Ejection Fraction><Electronic Health Record><Engineering><Enrollment><Environmental Science><Event><Funding><Generalized Growth><Genomics><Growth><HF with preserved ejection fraction><HFpEF><Health Care Technology><Health Technology><Heart><Heart Vascular><Heart failure><Heterogeneity><Hypertension><Image><Incidence><Inflammation><Inflammatory><Investigators><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Learning><Machine Learning><Metabolic><Metabolic syndrome><Mining><Molecular><Molecular Analysis><Morbidity><Morbidity - disease rate><NIH><National Institutes of Health><Obesity><Organ><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Patients><Phase><Phenotype><Plug-in><Population><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Progressive Disease><Proteomics><Pulmonary Hypertension><QOL><Quality of life><Rad.-PET><Records><Research><Research Institute><Research Personnel><Researchers><Role><Source><Syndrome><Systematics><Testing><Text><Therapeutic><Tissue Growth><United States><United States National Institutes of Health><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adiposity><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging associated disease><aging associated disorders><aging population><aging related disease><aging related disorders><atherosclerotic coronary disease><biomedical referral center><cardiac failure><cardiovascular disorder><career development><chronic kidney disease><circulatory system><clinical center><co-morbid><co-morbidity><cohort><college><collegiate><community clinic><comorbidity><connectome><coronary arterial disease><corpulence><developmental><diabetes><discovery mining><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><diverse populations><electronic data><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><functional status><heart failure and reduced ejection fraction><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart failure with reduced ejection fraction><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><indexing><innovate><innovation><innovative><insight><internet portal><literature mining><literature searching><m-Health><mHealth><machine based learning><medical college><medical schools><metabolism measurement><metabolomics><metabonomics><microbiome><minority communities><mobile health><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mortality><multi-ethnic><multidisciplinary><multiethnic><multiomics><multiple omics><next generation><novel><on-line portal><online portal><ontogeny><panomics><participant engagement><participant enrollment><patient engagement><patient enrollment><patient population><phenomics><phrases><population aging><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><preserved ejection fraction heart failure><programs><prospective><protocol development><recruit><referral center><remote monitoring><school of medicine><sex><skill acquisition><skill development><social role><text mining><text searching><translational research center><translational sciences center><web portal><web-based portal>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Javier Enrique Lopez

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$47,885
FY 2025

Project Title

A prospective multiethnic HFpEF cohort from California's Central Valley

Grant Number:

3U01HL160274-05S1

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT This is a new U01 application to establish a Clinical Center (CC) for a prospective multiethnic HFpEF cohort from California central valley for deep phenotyping analyses. The investigative team is diverse, multidisciplinary, and complementary with investigators from School of Medicine, Coll...

Research Terms

<Age><Agriculture><Area><Atrial Fibrillation><Auricular Fibrillation><Blood flow><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Catchment Area><Center for Translational Science Activities><Central Valley><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Classification><Clinic><Clinical><Clinical Research><Clinical Sciences><Clinical Study><Community Hospitals><Complex><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Country><Coupled><Data><Data Science><Data Set><Development><Diabetes Mellitus><Diastolic heart failure><Disease><Disorder><EFRAC><Ejection Fraction><Electronic Health Record><Engineering><Enrollment><Environmental Science><Event><Funding><Generalized Growth><Genomics><Growth><HF with preserved ejection fraction><HFpEF><Health Care Technology><Health Technology><Heart><Heart Vascular><Heart failure><Heterogeneity><Hypertension><Image><Incidence><Inflammation><Inflammatory><Investigators><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Learning><Machine Learning><Metabolic><Metabolic syndrome><Mining><Molecular><Molecular Analysis><Morbidity><Morbidity - disease rate><NIH><National Institutes of Health><Obesity><Organ><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Patients><Phase><Phenotype><Plug-in><Population><Population Heterogeneity><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Progressive Disease><Proteomics><Pulmonary Hypertension><QOL><Quality of life><Rad.-PET><Records><Research><Research Institute><Research Personnel><Researchers><Role><Source><Syndrome><Systematics><Testing><Text><Therapeutic><Tissue Growth><United States><United States National Institutes of Health><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adiposity><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging associated disease><aging associated disorders><aging population><aging related disease><aging related disorders><atherosclerotic coronary disease><biomedical referral center><cardiac failure><cardiovascular disorder><career development><chronic kidney disease><circulatory system><clinical center><co-morbid><co-morbidity><cohort><college><collegiate><community clinic><comorbidity><connectome><coronary arterial disease><corpulence><developmental><diabetes><discovery mining><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><diverse populations><electronic data><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><functional status><heart failure and reduced ejection fraction><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart failure with reduced ejection fraction><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><indexing><innovate><innovation><innovative><insight><internet portal><literature mining><literature searching><m-Health><mHealth><machine based learning><medical college><medical schools><metabolism measurement><metabolomics><metabonomics><microbiome><minority communities><mobile health><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><mortality><multi-ethnic><multidisciplinary><multiethnic><multiomics><multiple omics><next generation><novel><on-line portal><online portal><ontogeny><panomics><participant engagement><participant enrollment><patient engagement><patient enrollment><patient population><phenomics><phrases><population aging><population diversity><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><preserved ejection fraction heart failure><programs><prospective><protocol development><recruit><referral center><remote monitoring><school of medicine><sex><skill acquisition><skill development><social role><text mining><text searching><translational research center><translational sciences center><web portal><web-based portal>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Oliver Fiehn

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$26,460
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LEE E. GOLDSTEIN

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$26,460
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rima F Kaddurah-Daouk

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$26,460
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Wishart

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$26,460
FY 2025

Project Title

The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory

Grant Number:

3U01AG088562-02S2

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

It has become increasingly clear that environmental exposures, the genome, gut microbiome, diet, and lifestyle all affect an individual’s metabolic state contributing to brain health and disease, including Alzheimer’s disease (AD) and AD-related dementia (ADRDs). Our AD Metabolomics Consortium (ADMC...

Research Terms

<AD dementia><AD diagnostic><AD related dementia><ADRD><Acceleration><Address><Administrative Supplement><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnostic><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease diagnostic><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Animal Model><Animal Models and Related Studies><Atlases><Autopsy><Big Data><BigData><Bile Acids><Biochemical><Biologic Models><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><Brain imaging><Brain region><Categories><Cell Body><Cells><Cellular Immune Function><Chemical Exposure><Chemicals><Cholesterol Homeostasis><Classification><Clinical Data><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Communities><Complex><Consensus><D-Glucose><Data><Data Bases><Data Pooling><Databases><Dementia><Dextrose><Diet><Dietary Component><Dietary Intervention><Differences between sexes><Differs between sexes><Disease><Disease Marker><Disorder><Disturbance in cognition><Drugs><Encephalon><Encephalon Diseases><Environmental Exposure><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Ethnic Origin><Ethnicity><European><Exposure to><FDG PET><Failure><Food><Funding><GI microbiome><Generations><Genetic><Genetic Risk><Genome><Genomics><Geography><Glucose><Goals><Government><Health><Human><Image><Impaired cognition><Individual><Industry><Inflammation><Infrastructure><Intervention Studies><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Investigators><Investments><Joints><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Life Style><Lifestyle><Link><Liver><Long-term cohort study><Longitudinal cohort study><Maps><Measures><Medication><Medicine><Meta-Analysis><Metabolic><Metabolic Diseases><Metabolic Disorder><Mind><Mitochondria><Model System><Modeling><Modern Man><Molecular><Molecular Disease><Neighborhoods><Netherlands><Non-Profit Organizations><Nonprofit Organizations><Nutrition Interventions><Nutritional Interventions><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Pathogenesis><Pb element><Peripheral><Pharmaceutical Preparations><Phenotype><Pilot Projects><Plasma><Plasma Serum><Play><Population Study><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative measure><Preventive measure><Primary Senile Degenerative Dementia><Process><Rad.-PET><Reporting><Research><Research Infrastructure><Research Personnel><Research Resources><Research Specimen><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Secure><Sex Differences><Sexual differences><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Specimen><System><Systematics><Technology><Testing><Thesaurismosis><Time><Toxicant exposure><Work><aged brain><aging brain><bacteria in the gut><bio-markers><biobank><biologic marker><biomarker><biorepository><brain atrophy><brain health><brain visualization><cerebral atrophy><cholesterol metabolism><cognitive change><cognitive dysfunction><cognitive function><cognitive loss><cohort><comparative><cortical atrophy><data base><data harmonization><data integration><data sharing><diet intervention><diets><digestive tract microbiome><drug/agent><enteric microbiome><environmental chemical exposure><epidemiologic investigation><epidemiology study><exposome><fluorodeoxyglucose PET><fluorodeoxyglucose positron emission tomography><gastrointestinal microbiome><gut bacteria><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><harmonized data><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><human data><imaging><immune function><in vitro Model><insight><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><life style intervention><lifestyle intervention><lipidomics><liver function><metabolic imaging><metabolism disorder><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mitochondrial><model of animal><mouse model><murine model><necropsy><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pilot study><population-based study><population-level study><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><postmortem><pre-clinical><preclinical><primary degenerative dementia><resilience><resilient><senile dementia of the Alzheimer type><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><socio-economic><socio-economic disadvantage><socio-economic position><socio-economically><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomic position><socioeconomically><socioeconomically underprivileged><socioeconomics><studies of populations><study of the population><toxic exposure><toxicant>
View Full Project Details on NIH Reporter
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Shaul Druckmann

STANFORD UNIVERSITY, STANFORD, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$1
FY 2025

Project Title

Single-neuron population dynamics in human speech motor cortex for a speech prosthesis

Grant Number:

5U01DC019430-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/2/2021

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Augmentative and alternative communication (AAC) technology for people with severe speech and motor impairment (SSMI) continues to improve, with recent advances being made in the neural control of communication devices. In prior NIDCD-supported research, our research team developed a...

Research Terms

<AAC Device><AAC Intervention><Address><Amyotrophic Lateral Sclerosis><Amyotrophic Lateral Sclerosis Motor Neuron Disease><Area><Articulators><Augmentative and Alternative Communication><Brain><Brain Nervous System><Brain Stem Infarctions><Brainstem Infarctions><Brainstem Stroke><Broca's area><Cell Communication and Signaling><Cell Signaling><Chronic><Clinical Research><Clinical Study><Clinical Trials><Communication><Computers><Custom><Degenerative Neurologic Disorders><Devices><Dimensions><Disease><Disorder><Dorsal><Electrocorticogram><Electrodes><Encephalon><Face><Functional MRI><Functional Magnetic Resonance Imaging><Gehrig's Disease><Gestures><Goals><Hand><Handwriting><Human><Impairment><Implant><Individual><Inferior Frontal Convolution><Inferior frontal gyrus><Intention><Intracellular Communication and Signaling><Investigation><Language><Learning><Locked-In Syndrome><Lou Gehrig Disease><Macaca><Macaque><Machine Learning><Methods><Microelectrodes><Miniaturized Electrodes><Modeling><Modern Man><Modernization><Motor><Motor Cortex><Movement><Muscle><Muscle Tissue><NIDCD><National Institute on Deafness and Other Communication Disorders><Nerve Cells><Nerve Unit><Nervous System Degenerative Diseases><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurologic Disorders><Neurological Disorders><Neurons><Neurosciences><Output><Palsy><Paralysed><Participant><Performance><Persons><Plegia><Population><Population Dynamics><Precentral gyrus><Preparation><Production><Prosthesis><Prosthetic device><Prosthetics><QOL><Quality of life><Reporting><Research><Research Support><Safety><Signal Transduction><Signal Transduction Systems><Signaling><Site><Speech><Speed><System><Techniques><Technology><Testing><Text><Time><Utah><Voice><Writing><accurate speech><arm><arm movement><automated speech recognition><automatic speech recognition><awake><biological signal transduction><body movement><brain computer interface><communication device><customs><data to train><dataset to train><deep learning><deep learning method><deep learning strategy><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><design><designing><dynamic system><dynamical system><electrocorticography><experience><fMRI><faces><facial><hands><improved><insight><kinematic model><kinematics><machine based learning><machine learned algorithm><machine learning algorithm><machine learning based algorithm><motor impairment><movement impairment><movement limitation><muscular><neural><neural control><neural correlate><neural mechanism><neural regulation><neurodegenerative illness><neurological disease><neuromechanism><neuromodulation><neuromodulatory><neuronal><neuroregulation><non-human primate><nonhuman primate><orofacial><paralysis><paralytic><preparations><recurrent neural network><safety assessment><speech accuracy><training data>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JAIMIE M HENDERSON

STANFORD UNIVERSITY, STANFORD, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$1
FY 2025

Project Title

Single-neuron population dynamics in human speech motor cortex for a speech prosthesis

Grant Number:

5U01DC019430-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/2/2021

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Augmentative and alternative communication (AAC) technology for people with severe speech and motor impairment (SSMI) continues to improve, with recent advances being made in the neural control of communication devices. In prior NIDCD-supported research, our research team developed a...

Research Terms

<AAC Device><AAC Intervention><Address><Amyotrophic Lateral Sclerosis><Amyotrophic Lateral Sclerosis Motor Neuron Disease><Area><Articulators><Augmentative and Alternative Communication><Brain><Brain Nervous System><Brain Stem Infarctions><Brainstem Infarctions><Brainstem Stroke><Broca's area><Cell Communication and Signaling><Cell Signaling><Chronic><Clinical Research><Clinical Study><Clinical Trials><Communication><Computers><Custom><Degenerative Neurologic Disorders><Devices><Dimensions><Disease><Disorder><Dorsal><Electrocorticogram><Electrodes><Encephalon><Face><Functional MRI><Functional Magnetic Resonance Imaging><Gehrig's Disease><Gestures><Goals><Hand><Handwriting><Human><Impairment><Implant><Individual><Inferior Frontal Convolution><Inferior frontal gyrus><Intention><Intracellular Communication and Signaling><Investigation><Language><Learning><Locked-In Syndrome><Lou Gehrig Disease><Macaca><Macaque><Machine Learning><Methods><Microelectrodes><Miniaturized Electrodes><Modeling><Modern Man><Modernization><Motor><Motor Cortex><Movement><Muscle><Muscle Tissue><NIDCD><National Institute on Deafness and Other Communication Disorders><Nerve Cells><Nerve Unit><Nervous System Degenerative Diseases><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurologic Disorders><Neurological Disorders><Neurons><Neurosciences><Output><Palsy><Paralysed><Participant><Performance><Persons><Plegia><Population><Population Dynamics><Precentral gyrus><Preparation><Production><Prosthesis><Prosthetic device><Prosthetics><QOL><Quality of life><Reporting><Research><Research Support><Safety><Signal Transduction><Signal Transduction Systems><Signaling><Site><Speech><Speed><System><Techniques><Technology><Testing><Text><Time><Utah><Voice><Writing><accurate speech><arm><arm movement><automated speech recognition><automatic speech recognition><awake><biological signal transduction><body movement><brain computer interface><communication device><customs><data to train><dataset to train><deep learning><deep learning method><deep learning strategy><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><design><designing><dynamic system><dynamical system><electrocorticography><experience><fMRI><faces><facial><hands><improved><insight><kinematic model><kinematics><machine based learning><machine learned algorithm><machine learning algorithm><machine learning based algorithm><motor impairment><movement impairment><movement limitation><muscular><neural><neural control><neural correlate><neural mechanism><neural regulation><neurodegenerative illness><neurological disease><neuromechanism><neuromodulation><neuromodulatory><neuronal><neuroregulation><non-human primate><nonhuman primate><orofacial><paralysis><paralytic><preparations><recurrent neural network><safety assessment><speech accuracy><training data>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kari A Stephens

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$9,270,394
FY 2025

Project Title

National Alzheimer's Coordinating Center

Grant Number:

5U24AG072122-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/15/2021

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project summary/abstract NACC (as U01 AG016976, at University of Washington) has been active since 1999. The existing NACC infrastructure is described in the Facilities and Resources Section of this application. The broad goals of the past funding cycles are consistent with those of the current U24 ...

Research Terms

<AD dementia><AD prevention><AD related dementia><ADRD><Acceleration><Achievement><Achievement Attainment><Adoption><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer disease prevention><Alzheimer prevention><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Applied Research><Applied Science><Area><Award><Big Data><BigData><Biological Markers><Biometrics><Biometry><Biostatistics><Collaborations><Communication><Complex><Consultations><Contracting Opportunities><Contracts><Data><Data Bases><Data Collection><Data Coordinating Center><Data Coordination Center><Data Science><Data Set><Databases><Dementia><Early Diagnosis><Enrollment><Environment><Faculty><Funding><Future><Genetic><Genetic Diseases><Genomics><Goals><Heterogeneity><History><Image><Individual><Informatics><Infrastructure><Investigators><Leadership><Link><Medicine><Methodology><Methods><Mission><Modernization><Peer Review><Position><Positioning Attribute><Primary Senile Degenerative Dementia><Publications><Recording of previous events><Research><Research Peer Review><Research Personnel><Research Resources><Research Specimen><Research Support><Researchers><Resources><Risk Factors><Sampling><Scanning><Scientific Publication><Scientist><Secure><Services><Source><Specimen><Standardization><Techniques><Technology><Testing><Time><Translational Research><Translational Science><Universities><Washington><ages><bio-markers><biologic marker><biomarker><career><clinical database><clinical exam><clinical examination><cohort><community center><community centers><consultation><data access><data base><data resource><data sharing><data storage site><data visualization><deep learning><deep learning method><deep learning strategy><depository><digital data><disease heterogeneity><e-science><early detection><enroll><escience><experience><genetic condition><genetic disorder><high standard><histories><imaging><improved><innovate><innovation><innovative><instrument><interest><interoperability><meeting><meetings><neural imaging><neuro-imaging><neuroimaging><neurological imaging><neuropathologic><neuropathological><neuropathology><novel><primary degenerative dementia><programs><repository><senile dementia of the Alzheimer type><social media><success><tool><translation research><translational health research><translational health science><translational investigation><trend><web site><website>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Damien A Fair

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,728,827
FY 2025

Project Title

Healthy Brain and Child Development National Consortium Data Coordinating Center

Grant Number:

3U24DA055330-05S1

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/30/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY The landmark Healthy Brain and Child Development (HBCD) study will provide a representative reference data resource to the scientific community enabling unprecedented investigation of neurodevelopment and the impact of environmental, genetic, and biological factors on brain and behav...

Research Terms

<0-11 years old><Administrative Supplement><Affect><Ancillary Study><Assay><Behavior assessment><Behavioral><Bioassay><Biologic Factor><Biological><Biological Assay><Biological Factors><Biological Markers><Blood><Blood Reticuloendothelial System><Brain><Brain Nervous System><Child><Child Development><Child Health><Child Youth><Childhood><Children (0-21)><Code><Coding System><Collaborations><Collection><Communities><Data><Data Collection><Data Coordinating Center><Data Coordination Center><Data Set><Detection><Development><Drugs><Dryness><ELISA><Ecological impact><Encephalon><Ensure><Environmental Factor><Environmental Impact><Environmental Risk Factor><Enzyme-Linked Immunosorbent Assay><Family><Genetic><HEAL Initiative><Health><Helping End Addiction Long-term><Helping to End Addiction Long-term><Infant and Child Development><Investigation><Laboratories><Leadership><Life><Link><Literature><Medication><Modality><NIH><Nail plate><Nails><National Institutes of Health><Neural Development><Opiate Addiction><Opiate Dependence><Opiates><Opioid><Outcome><Parents><Patient Self-Report><Pharmaceutical Preparations><Pregnant Women><Protocol><Protocols documentation><Public Health><Public Policy><Quality Control><Reproducibility><Research><Research Specimen><Sampling><Secure><Self-Report><Shapes><Site><Specimen><Speed><Spottings><Standardization><Toxicology><United States><United States National Institutes of Health><Urine><Work><analytical method><behavioral assessment><behavioral health><bio-markers><biologic><biologic marker><biomarker><brain health><clinical care><cognitive assessment><cognitive testing><cohort><computerized data processing><cost><critical period><data collection site><data harmonization><data processing><data resource><design><designing><detection limit><developmental><drug detection><drug testing><drug/agent><early life exposure><environmental risk><enzyme linked immunoassay><evidence base><expectant mother><expectant women><expecting mother><expecting women><harmonized data><improved><individuals who are pregnant><infancy><infantile><kids><longitudinal data set><longitudinal dataset><neural imaging><neuro-imaging><neurodevelopment><neuroimaging><neurological imaging><neurophysiological><neurophysiology><non-medical opioid use><nonmedical opioid use><opiate misuse><opioid addiction><opioid dependence><opioid dependent><opioid misuse><parent><pediatric><people who are pregnant><post-natal development><postnatal development><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><recruit><socio-demographics><sociodemographics><substance use><substance using><success><those who are pregnant><tool><unborn><women who are pregnant><work group><working group><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christopher Daniel Smyser

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,728,827
FY 2025

Project Title

Healthy Brain and Child Development National Consortium Data Coordinating Center

Grant Number:

3U24DA055330-05S1

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/30/2021

End Date:

6/30/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY The landmark Healthy Brain and Child Development (HBCD) study will provide a representative reference data resource to the scientific community enabling unprecedented investigation of neurodevelopment and the impact of environmental, genetic, and biological factors on brain and behav...

Research Terms

<0-11 years old><Administrative Supplement><Affect><Ancillary Study><Assay><Behavior assessment><Behavioral><Bioassay><Biologic Factor><Biological><Biological Assay><Biological Factors><Biological Markers><Blood><Blood Reticuloendothelial System><Brain><Brain Nervous System><Child><Child Development><Child Health><Child Youth><Childhood><Children (0-21)><Code><Coding System><Collaborations><Collection><Communities><Data><Data Collection><Data Coordinating Center><Data Coordination Center><Data Set><Detection><Development><Drugs><Dryness><ELISA><Ecological impact><Encephalon><Ensure><Environmental Factor><Environmental Impact><Environmental Risk Factor><Enzyme-Linked Immunosorbent Assay><Family><Genetic><HEAL Initiative><Health><Helping End Addiction Long-term><Helping to End Addiction Long-term><Infant and Child Development><Investigation><Laboratories><Leadership><Life><Link><Literature><Medication><Modality><NIH><Nail plate><Nails><National Institutes of Health><Neural Development><Opiate Addiction><Opiate Dependence><Opiates><Opioid><Outcome><Parents><Patient Self-Report><Pharmaceutical Preparations><Pregnant Women><Protocol><Protocols documentation><Public Health><Public Policy><Quality Control><Reproducibility><Research><Research Specimen><Sampling><Secure><Self-Report><Shapes><Site><Specimen><Speed><Spottings><Standardization><Toxicology><United States><United States National Institutes of Health><Urine><Work><analytical method><behavioral assessment><behavioral health><bio-markers><biologic><biologic marker><biomarker><brain health><clinical care><cognitive assessment><cognitive testing><cohort><computerized data processing><cost><critical period><data collection site><data harmonization><data processing><data resource><design><designing><detection limit><developmental><drug detection><drug testing><drug/agent><early life exposure><environmental risk><enzyme linked immunoassay><evidence base><expectant mother><expectant women><expecting mother><expecting women><harmonized data><improved><individuals who are pregnant><infancy><infantile><kids><longitudinal data set><longitudinal dataset><neural imaging><neuro-imaging><neurodevelopment><neuroimaging><neurological imaging><neurophysiological><neurophysiology><non-medical opioid use><nonmedical opioid use><opiate misuse><opioid addiction><opioid dependence><opioid dependent><opioid misuse><parent><pediatric><people who are pregnant><post-natal development><postnatal development><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><recruit><socio-demographics><sociodemographics><substance use><substance using><success><those who are pregnant><tool><unborn><women who are pregnant><work group><working group><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Henry E. Wang

OHIO STATE UNIVERSITY, Columbus, OH

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,674,796
FY 2025

Project Title

1/2 – Pediatric Prehospital Airway Resuscitation Trial

Grant Number:

5UH3HL165019-03

Activity Code:

UH3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2023

End Date:

7/31/2029

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY We aim to answer the signature question of paramedic care; “What is the best way to manage the prehospital airway in critically ill children?” Cardiac arrest, respiratory failure, and major trauma are devastating critical conditions in children. Resuscitation from critical illness r...

Research Terms

<0-11 years old><AHCPR><AHRQ><Accounting><Address><Adverse Experience><Adverse event><Age><Agency for Health Care Policy and Research><Agency for Healthcare Research and Quality><Agreement><Airway failure><Applied Research><Applied Science><Asystole><Bayesian Analysis><Bayesian computation><Bayesian inference><Bayesian network analysis><Bayesian spatial analysis><Bayesian statistical analysis><Bayesian statistical inference><Bayesian statistics><Benefits and Risks><Brain><Brain Nervous System><Cardiac Arrest><Caring><Categories><Child><Child Care><Child Health><Child Youth><Childhood><Children (0-21)><Children's Hospital><Clinical><Clinical Trials Network><Communities><Complement><Complement Proteins><Complex><Consensus><Critical Care><Critical Illness><Critically Ill><Critically ill children><Data Bases><Databases><Dedications><Devices><Disease><Disorder><Dose><ED care><ER care><Emergency Care><Emergency Department care><Emergency Room care><Emergency care research><Emergency health care><Emergency medical care><Emergency research><Encephalon><Endotracheal Intubation><Ensure><Event><Gel><Guidelines><HRSA><Health Resources and Services Administration><Heart><Heart Arrest><Hospitals><IRB><IRBs><Informed Consent><Institutional Review Boards><International><Interview><Intratracheal Intubation><Knowledge><Laryngeal><Laryngeal Mask Airway><Laryngeal Masks><Larynx><Larynx Head and Neck><Life><Lung><Lung Respiratory System><Manuals><Masks><Medical Directors><O element><O2 element><Outcome><Oxygen><Paramedic><Paramedical Personnel><Patients><Pediatric Hospitals><Phase><Physician Executives><Pre-hospital care><Pre-hospitalization care><Prehospital care><Prehospitalization care><Protocol><Protocols documentation><Public Health><Puericulture><Recommendation><Research Resources><Resources><Respiratory Failure><Resuscitation><Safety><Secure><Seizures><Survival Rate><Techniques><Testing><Training><Trauma><Traumatic injury><Tube><United States Agency for Health Care Policy and Research><United States Agency for Healthcare Research and Quality><United States Health Resources and Services Administration><Variant><Variation><ages><child health care><clinical care><community consultation><compare effectiveness><complementation><critically ill child><data base><design><designing><evidence base><experience><improved><innovate><innovation><innovative><kids><life year loss><multidisciplinary><novel><operation><operations><out-of-hospital cardiac arrest><out-of-hospital sudden cardiac arrest><pediatric><pediatric care><pediatric emergency><pediatric health care><prevent><preventing><relative effectiveness><skills><synergism><tracheal intubation><trial design><trial enrollment><ventilation><voice box><years of life lost><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lauren Averett Byers

SLOAN-KETTERING INST CAN RESEARCH, NEW YORK, NY

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,379,839
FY 2025

Project Title

Coordinating center for the NCI small cell lung cancer research consortium

Grant Number:

5U24CA213274-09

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/24/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT The overarching goal of the NCI Small Cell Lung Cancer (SCLC) Coordinating Center has been to “break the logjam” of fundamental knowledge gaps resulting in a 30+ year lack of progress on this lethal malignancy that was designated a “recalcitrant cancer” by the US Congress and NCI. Our U24 C...

Research Terms

<Address><Administrative Coordination><Advocate><Area><Award><Bioinformatics><Biological><Biological Specimen database><Biometrics><Biometry><Biostatistics><Cancer Model><CancerModel><Cancers><Cataloging><Clinical><Clinical Treatment><Clinical Trials><Collaborations><Collection><Communication><Communities><Congresses><Data><Data Analyses><Data Analysis><Data Analytics><Data Bases><Databases><Development><Disease><Disorder><Early Diagnosis><Early Intervention><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Fostering><Funding><Funding Opportunities><GEM model><GEMM model><Generalized Growth><Generations><Genetic Data Banks><Genetic Data Bases><Genetic Databanks><Genetic Databases><Genetic Information Databases><Genetically Engineered Mouse><Goals><Grant><Growth><Health><Human><Immune Surveillance><Immunochemical Immunologic><Immunologic><Immunologic Surveillance><Immunological><Immunologically><Immunologics><Immunosurveillance><Individual><Institution><Investigators><Knowledge><Leadership><MDACC><Maintenance><Malignant Neoplasms><Malignant Tumor><Metastasis Suppression><Mice><Mice Mammals><Modeling><Modern Man><Molecular and Cellular Biology><Murine><Mus><Oat cell carcinoma><Oncogenic><PDX model><Pathology><Patient derived xenograft><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peer Review><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Principal Investigator><Proteomics><Publications><Research><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Role><Rotation><Scientific Publication><Secure><Small Cell Lung Cancer><Societies><Structure><Sum><Teleconferences><Therapeutic><Therapeutic Research><Tissue Growth><Translational trial><Universities><University of Texas M D Anderson Cancer Center><University of Texas MD Anderson Cancer Center><Utah><Work><anti-cancer immunotherapy><anti-cancer research><anticancer immunotherapy><biologic><biorepository database><biosample database><biospecimen database><cancer immunotherapy><cancer research><central database><clinical intervention><clinical therapy><clinical translation><clinically translatable><cohort><comparative><data base><data interpretation><depository><design><designing><developmental><disease model><disease prevention><disorder model><disorder prevention><early detection><epigenetically><genetically engineered mouse model><genetically engineered murine model><immune-based cancer therapies><immunotherapy for cancer><immunotherapy of cancer><improved><in vitro Model><in vivo><innovate><innovation><innovative><insight><lung oat cell carcinoma><lung small cell neuroendocrine carcinoma><malignancy><meeting><meetings><member><neoplasm/cancer><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutics><novel therapy><oat cell cancer><ontogeny><patient derived xenograft model><patient oriented outcomes><pre-clinical><preclinical><repository><small cell lung carcinoma><small cell undifferentiated carcinoma><social role><specimen database><success><synergism><tissue resource><transcriptomics><trial regimen><trial treatment><tumor><virtual><web site><website>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOHN D. MINNA

SLOAN-KETTERING INST CAN RESEARCH, NEW YORK, NY

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,379,839
FY 2025

Project Title

Coordinating center for the NCI small cell lung cancer research consortium

Grant Number:

5U24CA213274-09

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/24/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT The overarching goal of the NCI Small Cell Lung Cancer (SCLC) Coordinating Center has been to “break the logjam” of fundamental knowledge gaps resulting in a 30+ year lack of progress on this lethal malignancy that was designated a “recalcitrant cancer” by the US Congress and NCI. Our U24 C...

Research Terms

<Address><Administrative Coordination><Advocate><Area><Award><Bioinformatics><Biological><Biological Specimen database><Biometrics><Biometry><Biostatistics><Cancer Model><CancerModel><Cancers><Cataloging><Clinical><Clinical Treatment><Clinical Trials><Collaborations><Collection><Communication><Communities><Congresses><Data><Data Analyses><Data Analysis><Data Analytics><Data Bases><Databases><Development><Disease><Disorder><Early Diagnosis><Early Intervention><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Fostering><Funding><Funding Opportunities><GEM model><GEMM model><Generalized Growth><Generations><Genetic Data Banks><Genetic Data Bases><Genetic Databanks><Genetic Databases><Genetic Information Databases><Genetically Engineered Mouse><Goals><Grant><Growth><Health><Human><Immune Surveillance><Immunochemical Immunologic><Immunologic><Immunologic Surveillance><Immunological><Immunologically><Immunologics><Immunosurveillance><Individual><Institution><Investigators><Knowledge><Leadership><MDACC><Maintenance><Malignant Neoplasms><Malignant Tumor><Metastasis Suppression><Mice><Mice Mammals><Modeling><Modern Man><Molecular and Cellular Biology><Murine><Mus><Oat cell carcinoma><Oncogenic><PDX model><Pathology><Patient derived xenograft><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peer Review><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Principal Investigator><Proteomics><Publications><Research><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Role><Rotation><Scientific Publication><Secure><Small Cell Lung Cancer><Societies><Structure><Sum><Teleconferences><Therapeutic><Therapeutic Research><Tissue Growth><Translational trial><Universities><University of Texas M D Anderson Cancer Center><University of Texas MD Anderson Cancer Center><Utah><Work><anti-cancer immunotherapy><anti-cancer research><anticancer immunotherapy><biologic><biorepository database><biosample database><biospecimen database><cancer immunotherapy><cancer research><central database><clinical intervention><clinical therapy><clinical translation><clinically translatable><cohort><comparative><data base><data interpretation><depository><design><designing><developmental><disease model><disease prevention><disorder model><disorder prevention><early detection><epigenetically><genetically engineered mouse model><genetically engineered murine model><immune-based cancer therapies><immunotherapy for cancer><immunotherapy of cancer><improved><in vitro Model><in vivo><innovate><innovation><innovative><insight><lung oat cell carcinoma><lung small cell neuroendocrine carcinoma><malignancy><meeting><meetings><member><neoplasm/cancer><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutics><novel therapy><oat cell cancer><ontogeny><patient derived xenograft model><patient oriented outcomes><pre-clinical><preclinical><repository><small cell lung carcinoma><small cell undifferentiated carcinoma><social role><specimen database><success><synergism><tissue resource><transcriptomics><trial regimen><trial treatment><tumor><virtual><web site><website>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Trudy Gale Oliver

SLOAN-KETTERING INST CAN RESEARCH, NEW YORK, NY

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,379,839
FY 2025

Project Title

Coordinating center for the NCI small cell lung cancer research consortium

Grant Number:

5U24CA213274-09

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/24/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT The overarching goal of the NCI Small Cell Lung Cancer (SCLC) Coordinating Center has been to “break the logjam” of fundamental knowledge gaps resulting in a 30+ year lack of progress on this lethal malignancy that was designated a “recalcitrant cancer” by the US Congress and NCI. Our U24 C...

Research Terms

<Address><Administrative Coordination><Advocate><Area><Award><Bioinformatics><Biological><Biological Specimen database><Biometrics><Biometry><Biostatistics><Cancer Model><CancerModel><Cancers><Cataloging><Clinical><Clinical Treatment><Clinical Trials><Collaborations><Collection><Communication><Communities><Congresses><Data><Data Analyses><Data Analysis><Data Analytics><Data Bases><Databases><Development><Disease><Disorder><Early Diagnosis><Early Intervention><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Fostering><Funding><Funding Opportunities><GEM model><GEMM model><Generalized Growth><Generations><Genetic Data Banks><Genetic Data Bases><Genetic Databanks><Genetic Databases><Genetic Information Databases><Genetically Engineered Mouse><Goals><Grant><Growth><Health><Human><Immune Surveillance><Immunochemical Immunologic><Immunologic><Immunologic Surveillance><Immunological><Immunologically><Immunologics><Immunosurveillance><Individual><Institution><Investigators><Knowledge><Leadership><MDACC><Maintenance><Malignant Neoplasms><Malignant Tumor><Metastasis Suppression><Mice><Mice Mammals><Modeling><Modern Man><Molecular and Cellular Biology><Murine><Mus><Oat cell carcinoma><Oncogenic><PDX model><Pathology><Patient derived xenograft><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peer Review><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Principal Investigator><Proteomics><Publications><Research><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Role><Rotation><Scientific Publication><Secure><Small Cell Lung Cancer><Societies><Structure><Sum><Teleconferences><Therapeutic><Therapeutic Research><Tissue Growth><Translational trial><Universities><University of Texas M D Anderson Cancer Center><University of Texas MD Anderson Cancer Center><Utah><Work><anti-cancer immunotherapy><anti-cancer research><anticancer immunotherapy><biologic><biorepository database><biosample database><biospecimen database><cancer immunotherapy><cancer research><central database><clinical intervention><clinical therapy><clinical translation><clinically translatable><cohort><comparative><data base><data interpretation><depository><design><designing><developmental><disease model><disease prevention><disorder model><disorder prevention><early detection><epigenetically><genetically engineered mouse model><genetically engineered murine model><immune-based cancer therapies><immunotherapy for cancer><immunotherapy of cancer><improved><in vitro Model><in vivo><innovate><innovation><innovative><insight><lung oat cell carcinoma><lung small cell neuroendocrine carcinoma><malignancy><meeting><meetings><member><neoplasm/cancer><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutics><novel therapy><oat cell cancer><ontogeny><patient derived xenograft model><patient oriented outcomes><pre-clinical><preclinical><repository><small cell lung carcinoma><small cell undifferentiated carcinoma><social role><specimen database><success><synergism><tissue resource><transcriptomics><trial regimen><trial treatment><tumor><virtual><web site><website>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Charles M. Rudin

SLOAN-KETTERING INST CAN RESEARCH, NEW YORK, NY

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,379,839
FY 2025

Project Title

Coordinating center for the NCI small cell lung cancer research consortium

Grant Number:

5U24CA213274-09

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/24/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT The overarching goal of the NCI Small Cell Lung Cancer (SCLC) Coordinating Center has been to “break the logjam” of fundamental knowledge gaps resulting in a 30+ year lack of progress on this lethal malignancy that was designated a “recalcitrant cancer” by the US Congress and NCI. Our U24 C...

Research Terms

<Address><Administrative Coordination><Advocate><Area><Award><Bioinformatics><Biological><Biological Specimen database><Biometrics><Biometry><Biostatistics><Cancer Model><CancerModel><Cancers><Cataloging><Clinical><Clinical Treatment><Clinical Trials><Collaborations><Collection><Communication><Communities><Congresses><Data><Data Analyses><Data Analysis><Data Analytics><Data Bases><Databases><Development><Disease><Disorder><Early Diagnosis><Early Intervention><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Fostering><Funding><Funding Opportunities><GEM model><GEMM model><Generalized Growth><Generations><Genetic Data Banks><Genetic Data Bases><Genetic Databanks><Genetic Databases><Genetic Information Databases><Genetically Engineered Mouse><Goals><Grant><Growth><Health><Human><Immune Surveillance><Immunochemical Immunologic><Immunologic><Immunologic Surveillance><Immunological><Immunologically><Immunologics><Immunosurveillance><Individual><Institution><Investigators><Knowledge><Leadership><MDACC><Maintenance><Malignant Neoplasms><Malignant Tumor><Metastasis Suppression><Mice><Mice Mammals><Modeling><Modern Man><Molecular and Cellular Biology><Murine><Mus><Oat cell carcinoma><Oncogenic><PDX model><Pathology><Patient derived xenograft><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peer Review><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Principal Investigator><Proteomics><Publications><Research><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Role><Rotation><Scientific Publication><Secure><Small Cell Lung Cancer><Societies><Structure><Sum><Teleconferences><Therapeutic><Therapeutic Research><Tissue Growth><Translational trial><Universities><University of Texas M D Anderson Cancer Center><University of Texas MD Anderson Cancer Center><Utah><Work><anti-cancer immunotherapy><anti-cancer research><anticancer immunotherapy><biologic><biorepository database><biosample database><biospecimen database><cancer immunotherapy><cancer research><central database><clinical intervention><clinical therapy><clinical translation><clinically translatable><cohort><comparative><data base><data interpretation><depository><design><designing><developmental><disease model><disease prevention><disorder model><disorder prevention><early detection><epigenetically><genetically engineered mouse model><genetically engineered murine model><immune-based cancer therapies><immunotherapy for cancer><immunotherapy of cancer><improved><in vitro Model><in vivo><innovate><innovation><innovative><insight><lung oat cell carcinoma><lung small cell neuroendocrine carcinoma><malignancy><meeting><meetings><member><neoplasm/cancer><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutics><novel therapy><oat cell cancer><ontogeny><patient derived xenograft model><patient oriented outcomes><pre-clinical><preclinical><repository><small cell lung carcinoma><small cell undifferentiated carcinoma><social role><specimen database><success><synergism><tissue resource><transcriptomics><trial regimen><trial treatment><tumor><virtual><web site><website>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Scott Evans

GEORGE WASHINGTON UNIVERSITY, WASHINGTON, DC

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,180,407
FY 2025

Project Title

ENICTO Consortium Coordinating Center

Grant Number:

5U24CA271246-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/8/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY ABSTRACT The goal of the Exercise and Nutrition Interventions to Improve Cancer Treatment-related Outcomes (ENICTO) Consortium is to support and enhance exercise and/or medical nutrition intervention research designed to evaluate interventions that may improve cancer treatment-relate...

Research Terms

<Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Agreement><Ancillary Study><Bacterial Drug Resistance><Biometrics><Biometry><Biostatistics><Body Composition><Cancer Treatment><Cancers><Clinical Oncology><Clinical Research><Clinical Study><Collaborations><Collection><Common Data Element><Communication><Communities><Complications of Diabetes Mellitus><Cost effectiveness research><Data><Data Collection><Data Reporting><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diet><Dietary Intervention><E-Mail><ED visit><ER visit><Educational Materials><Electronic Mail><Email><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Ensure><Epidemiology><Evaluation><Exercise><Faculty><Failure><Goals><Health Sciences><History><Hospital Admission><Hospitalization><Iatrogenic Cancer><Interest Group><Interruption><Intervention><Investigators><Ketosis-Resistant Diabetes Mellitus><Lead><Leadership><Life><MFMU network><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Malnutrition><Maternal-Fetal Medicine Units><Maternal-Fetal Medicine Units (MFMU) Network><Maternal-Fetal Medicine Units Network><Maturity-Onset Diabetes Mellitus><Medical><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition><Nutrition Interventions><Nutritional Deficiency><Nutritional Interventions><Oncology><Oncology Cancer><Outcome><Outcome Study><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Pb element><Personalized medical approach><Physical activity><Pilot Projects><Policies><Prescribed exercise><Procedures><Protocol><Protocols documentation><Public Health Schools><Publications><Qualifying><Recommendation><Recording of previous events><Reporting><Research><Research Design><Research Personnel><Research Resources><Research Support><Researchers><Resources><Role><School Health Nursing><School Nursing><Scientific Publication><Site><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Study Type><System><T2 DM><T2D><T2DM><Therapy Related Malignant Neoplasm><Therapy Related Malignant Tumor><Therapy-Associated Cancers><Therapy-Related Cancer><Training><Treatment Protocols><Treatment Regimen><Treatment Schedule><Treatment outcome><Treatment-Associated Cancer><Treatment-Related Cancer><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Undernutrition><Universities><Washington><Work><Youth><Youth 10-21><adult onset diabetes><anti-bacterial drug resistance><anti-bacterial drug resistant><anti-bacterial resistance><anti-bacterial resistant><anti-cancer therapy><cancer therapy><cancer-directed therapy><cohort><comparative effectiveness study><data driven platform><data management><data platform><data representation><data representations><data resource><data sharing><design><designing><developmental><diabetes><diabetes control><diabetes mellitus control><diabetes prevention program><diet intervention><dietary deficiency><diets><dissemination science><electronic communication><epidemiologic><epidemiological><exercise intervention><exercise prescription><experience><flexibility><flexible><heavy metal Pb><heavy metal lead><histories><implementation science><improved><individualized approach><innovate><innovation><innovative><insulin secretion><juvenile><juvenile human><ketosis resistant diabetes><lean body mass><malignancy><malnourished><maturity onset diabetes><medical college><medical schools><meeting><meetings><multidisciplinary><neoplasm/cancer><novel><nutrition deficiency><nutrition deficiency disorder><nutritional deficiency disorder><performance site><personalized approach><physical activity intervention><pilot study><precision approach><research study><resistance to anti-bacterial><resistant to anti-bacterial><school of medicine><skills><social role><study design><success><tailored approach><type 2 DM><type II DM><type two diabetes><web site><website><work group><working group><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kimberly Z Robien

GEORGE WASHINGTON UNIVERSITY, WASHINGTON, DC

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,180,407
FY 2025

Project Title

ENICTO Consortium Coordinating Center

Grant Number:

5U24CA271246-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/8/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY ABSTRACT The goal of the Exercise and Nutrition Interventions to Improve Cancer Treatment-related Outcomes (ENICTO) Consortium is to support and enhance exercise and/or medical nutrition intervention research designed to evaluate interventions that may improve cancer treatment-relate...

Research Terms

<Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Agreement><Ancillary Study><Bacterial Drug Resistance><Biometrics><Biometry><Biostatistics><Body Composition><Cancer Treatment><Cancers><Clinical Oncology><Clinical Research><Clinical Study><Collaborations><Collection><Common Data Element><Communication><Communities><Complications of Diabetes Mellitus><Cost effectiveness research><Data><Data Collection><Data Reporting><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diet><Dietary Intervention><E-Mail><ED visit><ER visit><Educational Materials><Electronic Mail><Email><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Ensure><Epidemiology><Evaluation><Exercise><Faculty><Failure><Goals><Health Sciences><History><Hospital Admission><Hospitalization><Iatrogenic Cancer><Interest Group><Interruption><Intervention><Investigators><Ketosis-Resistant Diabetes Mellitus><Lead><Leadership><Life><MFMU network><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Malnutrition><Maternal-Fetal Medicine Units><Maternal-Fetal Medicine Units (MFMU) Network><Maternal-Fetal Medicine Units Network><Maturity-Onset Diabetes Mellitus><Medical><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition><Nutrition Interventions><Nutritional Deficiency><Nutritional Interventions><Oncology><Oncology Cancer><Outcome><Outcome Study><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Pb element><Personalized medical approach><Physical activity><Pilot Projects><Policies><Prescribed exercise><Procedures><Protocol><Protocols documentation><Public Health Schools><Publications><Qualifying><Recommendation><Recording of previous events><Reporting><Research><Research Design><Research Personnel><Research Resources><Research Support><Researchers><Resources><Role><School Health Nursing><School Nursing><Scientific Publication><Site><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Study Type><System><T2 DM><T2D><T2DM><Therapy Related Malignant Neoplasm><Therapy Related Malignant Tumor><Therapy-Associated Cancers><Therapy-Related Cancer><Training><Treatment Protocols><Treatment Regimen><Treatment Schedule><Treatment outcome><Treatment-Associated Cancer><Treatment-Related Cancer><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Undernutrition><Universities><Washington><Work><Youth><Youth 10-21><adult onset diabetes><anti-bacterial drug resistance><anti-bacterial drug resistant><anti-bacterial resistance><anti-bacterial resistant><anti-cancer therapy><cancer therapy><cancer-directed therapy><cohort><comparative effectiveness study><data driven platform><data management><data platform><data representation><data representations><data resource><data sharing><design><designing><developmental><diabetes><diabetes control><diabetes mellitus control><diabetes prevention program><diet intervention><dietary deficiency><diets><dissemination science><electronic communication><epidemiologic><epidemiological><exercise intervention><exercise prescription><experience><flexibility><flexible><heavy metal Pb><heavy metal lead><histories><implementation science><improved><individualized approach><innovate><innovation><innovative><insulin secretion><juvenile><juvenile human><ketosis resistant diabetes><lean body mass><malignancy><malnourished><maturity onset diabetes><medical college><medical schools><meeting><meetings><multidisciplinary><neoplasm/cancer><novel><nutrition deficiency><nutrition deficiency disorder><nutritional deficiency disorder><performance site><personalized approach><physical activity intervention><pilot study><precision approach><research study><resistance to anti-bacterial><resistant to anti-bacterial><school of medicine><skills><social role><study design><success><tailored approach><type 2 DM><type II DM><type two diabetes><web site><website><work group><working group><youth age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lee Cooper

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,049,460
FY 2025

Project Title

Brain Digital Slide Archive: An Open Source Platform for data sharing and analysis of digital neuropathology

Grant Number:

4U24NS133949-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/19/2023

End Date:

8/31/2028

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Recent advances in machine learning and computer vision have had transformative effects on the medical imaging field. Algorithms can now automatically identify patterns and objects in images, often with a degree of precision rivaling human experts for certain tasks. Key to these advances is the avai...

Research Terms

<AD dementia><AD related dementia><ADRD><Address><Adopted><Agreement><Algorithmic Analyses><Algorithmic Analysis><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnosis><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease diagnosis><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Analyses of Algorithms><Analysis of Algorithms><Archives><Body Tissues><Brain><Brain Nervous System><Brain imaging><Brain region><California><Cancers><Categories><Clinical><Collaborations><Communities><Complement><Complement Proteins><Computer Vision Systems><Computer software><Data><Data Analyses><Data Analysis><Data Set><Development><Diagnosis><Diagnostic><Encephalon><Engineering><Ensure><Evaluation><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Foundations><Funding><General Radiology><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Geography><Grant><Heterogeneity><Histologic><Histologically><Histology><Human><Image><Image Analyses><Image Analysis><Imaging technology><Individual><Informatics><Infrastructure><Institution><Investigators><Jobs><Legal><Libraries><Link><Location><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Malignant Neoplasms><Malignant Tumor><Manuals><Manufacturer><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metadata><Methods><Microscopic><Modeling><Modern Man><Monitor><NCI Organization><NIH><NMR Imaging><NMR Tomography><Names><National Cancer Institute><National Institutes of Health><Nerve Degeneration><Neurofibrillary Tangles><Neuron Degeneration><Nomenclature><Nuclear Magnetic Resonance Imaging><Occupations><Pathology><Pattern><Peer Review><Primary Senile Degenerative Dementia><Privacy><Process><Professional Positions><Radiology><Radiology Specialty><Readability><Research><Research Personnel><Research Resources><Researchers><Resources><Running><Scheme><Science><Secure><Security><Site><Slide><Software><Staging><Staining method><Stains><Standardization><Survey Instrument><Surveys><System><TCGA><Technology><Testing><The Cancer Genome Atlas><Tissues><Training><United States National Institutes of Health><Universities><Visualization><Zeugmatography><advanced analytics><brain tissue><brain visualization><complementation><computer imaging><computer vision><data dictionary><data driven platform><data interpretation><data platform><data quality><data sharing><data standardization><data standards><design><designing><developmental><digital><digital imaging><file format><geographic site><image evaluation><image interpretation><imaging><imaging system><improved><innovate><innovation><innovative><internet based platform><internet platform><machine based learning><machine learned algorithm><machine learning algorithm><machine learning based algorithm><machine learning based model><machine learning model><malignancy><meta data><metadata standards><microscope imaging><microscopic imaging><microscopy imaging><multidisciplinary><name><named><naming><neoplasm/cancer><neural degeneration><neurodegeneration><neurodegenerative><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neurological degeneration><neuronal degeneration><neuropathologic><neuropathological><neuropathology><open source><open source tool><open source toolkit><primary degenerative dementia><public health relevance><senile dementia of the Alzheimer type><shareable platform><sharing platform><statistics><tangle><tool><web based platform><web based system><web enabled platform><web platform><web tool><web-based tool><whole slide imaging>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Brittany Nicole Dugger

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,049,460
FY 2025

Project Title

Brain Digital Slide Archive: An Open Source Platform for data sharing and analysis of digital neuropathology

Grant Number:

4U24NS133949-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/19/2023

End Date:

8/31/2028

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Recent advances in machine learning and computer vision have had transformative effects on the medical imaging field. Algorithms can now automatically identify patterns and objects in images, often with a degree of precision rivaling human experts for certain tasks. Key to these advances is the avai...

Research Terms

<AD dementia><AD related dementia><ADRD><Address><Adopted><Agreement><Algorithmic Analyses><Algorithmic Analysis><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnosis><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease diagnosis><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Analyses of Algorithms><Analysis of Algorithms><Archives><Body Tissues><Brain><Brain Nervous System><Brain imaging><Brain region><California><Cancers><Categories><Clinical><Collaborations><Communities><Complement><Complement Proteins><Computer Vision Systems><Computer software><Data><Data Analyses><Data Analysis><Data Set><Development><Diagnosis><Diagnostic><Encephalon><Engineering><Ensure><Evaluation><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Foundations><Funding><General Radiology><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Geography><Grant><Heterogeneity><Histologic><Histologically><Histology><Human><Image><Image Analyses><Image Analysis><Imaging technology><Individual><Informatics><Infrastructure><Institution><Investigators><Jobs><Legal><Libraries><Link><Location><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Malignant Neoplasms><Malignant Tumor><Manuals><Manufacturer><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metadata><Methods><Microscopic><Modeling><Modern Man><Monitor><NCI Organization><NIH><NMR Imaging><NMR Tomography><Names><National Cancer Institute><National Institutes of Health><Nerve Degeneration><Neurofibrillary Tangles><Neuron Degeneration><Nomenclature><Nuclear Magnetic Resonance Imaging><Occupations><Pathology><Pattern><Peer Review><Primary Senile Degenerative Dementia><Privacy><Process><Professional Positions><Radiology><Radiology Specialty><Readability><Research><Research Personnel><Research Resources><Researchers><Resources><Running><Scheme><Science><Secure><Security><Site><Slide><Software><Staging><Staining method><Stains><Standardization><Survey Instrument><Surveys><System><TCGA><Technology><Testing><The Cancer Genome Atlas><Tissues><Training><United States National Institutes of Health><Universities><Visualization><Zeugmatography><advanced analytics><brain tissue><brain visualization><complementation><computer imaging><computer vision><data dictionary><data driven platform><data interpretation><data platform><data quality><data sharing><data standardization><data standards><design><designing><developmental><digital><digital imaging><file format><geographic site><image evaluation><image interpretation><imaging><imaging system><improved><innovate><innovation><innovative><internet based platform><internet platform><machine based learning><machine learned algorithm><machine learning algorithm><machine learning based algorithm><machine learning based model><machine learning model><malignancy><meta data><metadata standards><microscope imaging><microscopic imaging><microscopy imaging><multidisciplinary><name><named><naming><neoplasm/cancer><neural degeneration><neurodegeneration><neurodegenerative><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neurological degeneration><neuronal degeneration><neuropathologic><neuropathological><neuropathology><open source><open source tool><open source toolkit><primary degenerative dementia><public health relevance><senile dementia of the Alzheimer type><shareable platform><sharing platform><statistics><tangle><tool><web based platform><web based system><web enabled platform><web platform><web tool><web-based tool><whole slide imaging>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Andrew Gutman

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,049,460
FY 2025

Project Title

Brain Digital Slide Archive: An Open Source Platform for data sharing and analysis of digital neuropathology

Grant Number:

4U24NS133949-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/19/2023

End Date:

8/31/2028

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Recent advances in machine learning and computer vision have had transformative effects on the medical imaging field. Algorithms can now automatically identify patterns and objects in images, often with a degree of precision rivaling human experts for certain tasks. Key to these advances is the avai...

Research Terms

<AD dementia><AD related dementia><ADRD><Address><Adopted><Agreement><Algorithmic Analyses><Algorithmic Analysis><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnosis><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease diagnosis><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Analyses of Algorithms><Analysis of Algorithms><Archives><Body Tissues><Brain><Brain Nervous System><Brain imaging><Brain region><California><Cancers><Categories><Clinical><Collaborations><Communities><Complement><Complement Proteins><Computer Vision Systems><Computer software><Data><Data Analyses><Data Analysis><Data Set><Development><Diagnosis><Diagnostic><Encephalon><Engineering><Ensure><Evaluation><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Foundations><Funding><General Radiology><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Geography><Grant><Heterogeneity><Histologic><Histologically><Histology><Human><Image><Image Analyses><Image Analysis><Imaging technology><Individual><Informatics><Infrastructure><Institution><Investigators><Jobs><Legal><Libraries><Link><Location><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Malignant Neoplasms><Malignant Tumor><Manuals><Manufacturer><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metadata><Methods><Microscopic><Modeling><Modern Man><Monitor><NCI Organization><NIH><NMR Imaging><NMR Tomography><Names><National Cancer Institute><National Institutes of Health><Nerve Degeneration><Neurofibrillary Tangles><Neuron Degeneration><Nomenclature><Nuclear Magnetic Resonance Imaging><Occupations><Pathology><Pattern><Peer Review><Primary Senile Degenerative Dementia><Privacy><Process><Professional Positions><Radiology><Radiology Specialty><Readability><Research><Research Personnel><Research Resources><Researchers><Resources><Running><Scheme><Science><Secure><Security><Site><Slide><Software><Staging><Staining method><Stains><Standardization><Survey Instrument><Surveys><System><TCGA><Technology><Testing><The Cancer Genome Atlas><Tissues><Training><United States National Institutes of Health><Universities><Visualization><Zeugmatography><advanced analytics><brain tissue><brain visualization><complementation><computer imaging><computer vision><data dictionary><data driven platform><data interpretation><data platform><data quality><data sharing><data standardization><data standards><design><designing><developmental><digital><digital imaging><file format><geographic site><image evaluation><image interpretation><imaging><imaging system><improved><innovate><innovation><innovative><internet based platform><internet platform><machine based learning><machine learned algorithm><machine learning algorithm><machine learning based algorithm><machine learning based model><machine learning model><malignancy><meta data><metadata standards><microscope imaging><microscopic imaging><microscopy imaging><multidisciplinary><name><named><naming><neoplasm/cancer><neural degeneration><neurodegeneration><neurodegenerative><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neurological degeneration><neuronal degeneration><neuropathologic><neuropathological><neuropathology><open source><open source tool><open source toolkit><primary degenerative dementia><public health relevance><senile dementia of the Alzheimer type><shareable platform><sharing platform><statistics><tangle><tool><web based platform><web based system><web enabled platform><web platform><web tool><web-based tool><whole slide imaging>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Thomas Michael Pearce

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,049,460
FY 2025

Project Title

Brain Digital Slide Archive: An Open Source Platform for data sharing and analysis of digital neuropathology

Grant Number:

4U24NS133949-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/19/2023

End Date:

8/31/2028

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Recent advances in machine learning and computer vision have had transformative effects on the medical imaging field. Algorithms can now automatically identify patterns and objects in images, often with a degree of precision rivaling human experts for certain tasks. Key to these advances is the avai...

Research Terms

<AD dementia><AD related dementia><ADRD><Address><Adopted><Agreement><Algorithmic Analyses><Algorithmic Analysis><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's diagnosis><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease diagnosis><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Analyses of Algorithms><Analysis of Algorithms><Archives><Body Tissues><Brain><Brain Nervous System><Brain imaging><Brain region><California><Cancers><Categories><Clinical><Collaborations><Communities><Complement><Complement Proteins><Computer Vision Systems><Computer software><Data><Data Analyses><Data Analysis><Data Set><Development><Diagnosis><Diagnostic><Encephalon><Engineering><Ensure><Evaluation><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Foundations><Funding><General Radiology><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Geography><Grant><Heterogeneity><Histologic><Histologically><Histology><Human><Image><Image Analyses><Image Analysis><Imaging technology><Individual><Informatics><Infrastructure><Institution><Investigators><Jobs><Legal><Libraries><Link><Location><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Malignant Neoplasms><Malignant Tumor><Manuals><Manufacturer><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metadata><Methods><Microscopic><Modeling><Modern Man><Monitor><NCI Organization><NIH><NMR Imaging><NMR Tomography><Names><National Cancer Institute><National Institutes of Health><Nerve Degeneration><Neurofibrillary Tangles><Neuron Degeneration><Nomenclature><Nuclear Magnetic Resonance Imaging><Occupations><Pathology><Pattern><Peer Review><Primary Senile Degenerative Dementia><Privacy><Process><Professional Positions><Radiology><Radiology Specialty><Readability><Research><Research Personnel><Research Resources><Researchers><Resources><Running><Scheme><Science><Secure><Security><Site><Slide><Software><Staging><Staining method><Stains><Standardization><Survey Instrument><Surveys><System><TCGA><Technology><Testing><The Cancer Genome Atlas><Tissues><Training><United States National Institutes of Health><Universities><Visualization><Zeugmatography><advanced analytics><brain tissue><brain visualization><complementation><computer imaging><computer vision><data dictionary><data driven platform><data interpretation><data platform><data quality><data sharing><data standardization><data standards><design><designing><developmental><digital><digital imaging><file format><geographic site><image evaluation><image interpretation><imaging><imaging system><improved><innovate><innovation><innovative><internet based platform><internet platform><machine based learning><machine learned algorithm><machine learning algorithm><machine learning based algorithm><machine learning based model><machine learning model><malignancy><meta data><metadata standards><microscope imaging><microscopic imaging><microscopy imaging><multidisciplinary><name><named><naming><neoplasm/cancer><neural degeneration><neurodegeneration><neurodegenerative><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neurological degeneration><neuronal degeneration><neuropathologic><neuropathological><neuropathology><open source><open source tool><open source toolkit><primary degenerative dementia><public health relevance><senile dementia of the Alzheimer type><shareable platform><sharing platform><statistics><tangle><tool><web based platform><web based system><web enabled platform><web platform><web tool><web-based tool><whole slide imaging>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

John Kubale

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,028,995
FY 2025

Project Title

Consortium Coordinating Center for Social, Behavioral, and Economic Research on Public Health Emergencies

Grant Number:

5U24AG076462-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/30/2021

End Date:

9/30/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract Over the past 60 years, the Inter-university Consortium for Political and Social Research (ICPSR) has successfully coordinated the research needs for over 800 universities and research institutes. This work has led to the expanded use of secondary data, the development of in...

Research Terms

<Access to Information><Area><Behavioral><Behavioral Sciences><Black American><Collaborations><Communication><Communities><Complex><Data><Data Science><Development><Disasters><Economics><Fostering><Funding><Generalized Growth><Generations><Goals><Growth><Health><Information Distribution><Infrastructure><Interdisciplinary Research><Interdisciplinary Study><International><Investigators><Investments><Longitudinal Studies><Methods><Michigan><Mission><Modality><Modeling><Multidisciplinary Collaboration><Multidisciplinary Research><NIH><National Institutes of Health><Pilot Projects><Play><Policies><Policy Maker><Politics><Productivity><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Reporting><Research><Research Grants><Research Institute><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Role><Running><Scientific Publication><Social Sciences><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Survey Instrument><Surveys><Tissue Growth><Training><United States National Institutes of Health><Universities><Work><behavioral and social science><data resource><data sharing><developmental><economic><information model><innovate><innovation><innovative><long-term study><longitudinal outcome studies><meeting><meetings><ontogeny><open data><open science><open-source data><outreach to information><pandemic><pandemic disease><pilot study><podcast><population based><population health><programs><public health emergency><public health research><research and methods><social><social role><statistical analysis><web site><webinar><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Margaret Catherine Levenstein

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,028,995
FY 2025

Project Title

Consortium Coordinating Center for Social, Behavioral, and Economic Research on Public Health Emergencies

Grant Number:

5U24AG076462-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/30/2021

End Date:

9/30/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract Over the past 60 years, the Inter-university Consortium for Political and Social Research (ICPSR) has successfully coordinated the research needs for over 800 universities and research institutes. This work has led to the expanded use of secondary data, the development of in...

Research Terms

<Access to Information><Area><Behavioral><Behavioral Sciences><Black American><Collaborations><Communication><Communities><Complex><Data><Data Science><Development><Disasters><Economics><Fostering><Funding><Generalized Growth><Generations><Goals><Growth><Health><Information Distribution><Infrastructure><Interdisciplinary Research><Interdisciplinary Study><International><Investigators><Investments><Longitudinal Studies><Methods><Michigan><Mission><Modality><Modeling><Multidisciplinary Collaboration><Multidisciplinary Research><NIH><National Institutes of Health><Pilot Projects><Play><Policies><Policy Maker><Politics><Productivity><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Reporting><Research><Research Grants><Research Institute><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Role><Running><Scientific Publication><Social Sciences><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Survey Instrument><Surveys><Tissue Growth><Training><United States National Institutes of Health><Universities><Work><behavioral and social science><data resource><data sharing><developmental><economic><information model><innovate><innovation><innovative><long-term study><longitudinal outcome studies><meeting><meetings><ontogeny><open data><open science><open-source data><outreach to information><pandemic><pandemic disease><pilot study><podcast><population based><population health><programs><public health emergency><public health research><research and methods><social><social role><statistical analysis><web site><webinar><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

J. Jack LEE

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,010,953
FY 2025

Project Title

PASSCODE (Pancreatic Adenocarcinoma Stromal Reprograming ConSortium COordination, Data Management and Education)

Grant Number:

7U24CA274274-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/16/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT A defining feature of Pancreatic ductal adenocarcinoma (PDAC) is the presence of a host stromal response, which is characteristically more robust (“desmoplastic”) than many solid cancers. Stromal elements, including cancer-associated fibroblasts (CAFs) and the extracellular matrix, are pivo...

Research Terms

<American><American Cancer Society><Area><Assay><Basic Research><Basic Science><Bioassay><Bioinformatics><Biological Assay><Biometrics><Biometry><Biostatistics><Body Tissues><Cancer Biology><Cancer Cause><Cancer Etiology><Cancers><Cataloging><Cell Body><Cell-Extracellular Matrix><Cells><Clinical><Clinical Trials Design><Cloud Computing><Cloud Infrastructure><Collaborations><Communication><Communities><Computational Biology><Cues><Data><Data Collection><Data Management Core><Data Science><Data Storage and Retrieval><Dedications><Desmoplastic><Desmoplastic Reaction><Diagnosis><Disease><Disease Outcome><Disorder><ECM><Ecologic Systems><Ecological Systems><Ecosystem><Education><Education and Outreach><Educational Activities><Educational aspects><Educational workshop><Elements><Ensure><Extracellular Matrix><Fibroblasts><Funding><Generalized Growth><Genetic><Goals><Group Meetings><Growth><Heterogeneity><Immune><Immunes><Infrastructure><Instruction and Outreach><Intranet><Investigators><Lymphovascular><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant neoplasm of pancreas><Mentorship><Mission><Molecular><NIH><National Institutes of Health><Outcome><Pancreas Adenocarcinoma><Pancreas Cancer><Pancreas Ductal Adenocarcinoma><Pancreatic Adenocarcinoma><Pancreatic Cancer><Pancreatic Ductal Adenocarcinoma><Pathogenesis><Pathology><Patients><Persons><Policies><Procedures><Reagent><Registries><Regulation><Research><Research Activity><Research Personnel><Researchers><Role><Secure><Site><Site Visit><Solid><Specificity><Stromal Neoplasm><Stromal Tumor><System><Therapeutic><Time><Tissue Growth><Tissues><Training and Outreach><Transfer Agreement><Translational Research><Translational Science><Tumor Cell><Tumor Promotion><Tutoring and Outreach><Twitter><Underrepresented Ethnic Minority><Underrepresented Minority><United States><United States National Institutes of Health><Workshop><analytical tool><biobank><biorepository><cancer genetics><cancer immunology><cancer microenvironment><cloud based computing><cloud computer><computational resources><computer biology><computing resources><conference><convention><data dissemination><data exchange><data harmonization><data management><data management and coordinating center><data management center><data retrieval><data storage><data transfer><data transmission><harmonized data><improved><innovate><innovation><innovative><malignancy><material transfer agreement><meeting><meetings><member><microbiome><minority trainee><molecular pathology><mortality><multi-modal data><multi-modal datasets><multidisciplinary><multimodal data><multimodal datasets><neoplasm immunology><neoplasm/cancer><neoplastic cell><ontogeny><pancreas visualization><pancreatic carcinogenesis><pancreatic malignancy><pancreatic oncogenesis><pancreatic tumorigenesis><programs><research study><response><shared data base><shared database><social media><social role><success><summit><survival outcome><symposia><symposium><translation research><translational investigation><tumor><tumor immunology><tumor microenvironment><under-representation of minorities><under-represented minority><underrepresentation of minorities><virtual><web site><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ANIRBAN MAITRA

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,010,953
FY 2025

Project Title

PASSCODE (Pancreatic Adenocarcinoma Stromal Reprograming ConSortium COordination, Data Management and Education)

Grant Number:

7U24CA274274-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/16/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT A defining feature of Pancreatic ductal adenocarcinoma (PDAC) is the presence of a host stromal response, which is characteristically more robust (“desmoplastic”) than many solid cancers. Stromal elements, including cancer-associated fibroblasts (CAFs) and the extracellular matrix, are pivo...

Research Terms

<American><American Cancer Society><Area><Assay><Basic Research><Basic Science><Bioassay><Bioinformatics><Biological Assay><Biometrics><Biometry><Biostatistics><Body Tissues><Cancer Biology><Cancer Cause><Cancer Etiology><Cancers><Cataloging><Cell Body><Cell-Extracellular Matrix><Cells><Clinical><Clinical Trials Design><Cloud Computing><Cloud Infrastructure><Collaborations><Communication><Communities><Computational Biology><Cues><Data><Data Collection><Data Management Core><Data Science><Data Storage and Retrieval><Dedications><Desmoplastic><Desmoplastic Reaction><Diagnosis><Disease><Disease Outcome><Disorder><ECM><Ecologic Systems><Ecological Systems><Ecosystem><Education><Education and Outreach><Educational Activities><Educational aspects><Educational workshop><Elements><Ensure><Extracellular Matrix><Fibroblasts><Funding><Generalized Growth><Genetic><Goals><Group Meetings><Growth><Heterogeneity><Immune><Immunes><Infrastructure><Instruction and Outreach><Intranet><Investigators><Lymphovascular><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant neoplasm of pancreas><Mentorship><Mission><Molecular><NIH><National Institutes of Health><Outcome><Pancreas Adenocarcinoma><Pancreas Cancer><Pancreas Ductal Adenocarcinoma><Pancreatic Adenocarcinoma><Pancreatic Cancer><Pancreatic Ductal Adenocarcinoma><Pathogenesis><Pathology><Patients><Persons><Policies><Procedures><Reagent><Registries><Regulation><Research><Research Activity><Research Personnel><Researchers><Role><Secure><Site><Site Visit><Solid><Specificity><Stromal Neoplasm><Stromal Tumor><System><Therapeutic><Time><Tissue Growth><Tissues><Training and Outreach><Transfer Agreement><Translational Research><Translational Science><Tumor Cell><Tumor Promotion><Tutoring and Outreach><Twitter><Underrepresented Ethnic Minority><Underrepresented Minority><United States><United States National Institutes of Health><Workshop><analytical tool><biobank><biorepository><cancer genetics><cancer immunology><cancer microenvironment><cloud based computing><cloud computer><computational resources><computer biology><computing resources><conference><convention><data dissemination><data exchange><data harmonization><data management><data management and coordinating center><data management center><data retrieval><data storage><data transfer><data transmission><harmonized data><improved><innovate><innovation><innovative><malignancy><material transfer agreement><meeting><meetings><member><microbiome><minority trainee><molecular pathology><mortality><multi-modal data><multi-modal datasets><multidisciplinary><multimodal data><multimodal datasets><neoplasm immunology><neoplasm/cancer><neoplastic cell><ontogeny><pancreas visualization><pancreatic carcinogenesis><pancreatic malignancy><pancreatic oncogenesis><pancreatic tumorigenesis><programs><research study><response><shared data base><shared database><social media><social role><success><summit><survival outcome><symposia><symposium><translation research><translational investigation><tumor><tumor immunology><tumor microenvironment><under-representation of minorities><under-represented minority><underrepresentation of minorities><virtual><web site><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Emily Baumrin

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 42/100
Training-friendly
Active award
Career award
$173,228
FY 2026

Project Title

Development and validation of a patient-reported outcome measure to improve quality of life related to cutaneous chronic GVHD

Grant Number:

5K23AR085191-02

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/2/2024

End Date:

11/30/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Candidate: I am an Assistant Professor of Dermatology and Medicine at the University of Pennsylvania and a physician-scientist with a Master of Science in Clinical Epidemiology as well as expertise caring for patients with GVHD. I have a strong track record of published research at t...

Research Terms

<Allogenic><Biometrics><Biometry><Biostatistics><Cancer Center><Cancers><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Chronic><Chronic GVHD><Client satisfaction><Clinical><Clinical Trials><Clinical Trials Design><Collection><Consensus><Cross-Sectional Studies><Cross-Sectional Survey><Cutaneous><Cutaneous Disorder><Data Set><Delphi Study><Dermatologic><Dermatological><Dermatologist><Dermatology><Dermatoses><Development><Device or Instrument Development><Dimensions><Disease><Disease Frequency Surveys><Disorder><Enrollment><FDA approved><Goals><HSC transplantation><Health><Hematopoietic Stem Cell Transplant><Hematopoietic Stem Cell Transplantation><Human><Impaired health><Impairment><Intervention><Intervention Studies><Interview><K-Awards><K-Series Research Career Programs><Label><Lived experience><Lived experiences><Malignant Neoplasms><Malignant Tumor><Manuscripts><Master of Science><Master's Degree><Measures><Medicine><Mentors><Mentorship><Methods><Modern Man><Modernization><Morbidity><Multi-center studies><Multicenter Studies><Observational Study><Outcome><Outcome Measure><Pain><Painful><Patient Care><Patient Care Delivery><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patient Satisfaction><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pennsylvania><Perception><Physical Function><Physicians><Progenitor Cell Transplantation><Property><Prospective Studies><Prospective, cohort study><Protocol><Protocols documentation><Psychometrics><Publishing><QOL><QOL improvement><Quality of life><Reporting><Research><Research Career Program><Research Methodology><Research Methods><Resistance><Risk><Sampling><Science><Scientist><Selection for Treatments><Severities><Severity of illness><Skin><Skin Diseases><Skin Diseases and Manifestations><Standardization><Stem Cell Transplantation><Stem cell transplant><Structure><Symptoms><Testing><Therapeutic><Thick><Thickness><Training><Transplantation><Treatment Efficacy><United States><Universities><Validation><Validity and Reliability><blood stem cell transplantation><burden of disease><burden of illness><care for patients><care of patients><career><caring for patients><chronic graft versus host disease><chronic graft vs host disease><chronic graft vs. host disease><chronic inflammatory skin><chronic itch><chronic pruritus><clinical epidemiology><clinical practice><cognitive interview><cost><cross-sectional research study><cutaneous disease><dermal disease><dermal disorder><design><designing><developmental><device development><disease burden><disease severity><emotional distress><enroll><ethnic diversity><ethnically diverse><experience><feeling distress><feeling upset><functional disability><health related quality of life><hematopoietic cell transplantation><hematopoietic cellular transplantation><hematopoietic progenitor cell transplantation><high risk><improved><improved outcome><improvements in QOL><improvements in quality of life><instrument><instrument development><intervention efficacy><intervention research><interventional research><interventional study><interventions research><malignancy><measurable outcome><member><mortality><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><observational research study><observational survey><outcome measurement><patient centered><patient oriented><patient oriented outcomes><predict clinical outcome><prevent><preventing><professor><progenitor transplantation><prospective><prospective research study><prospective survey><psychologic><psychological><quality of life improvement><racial diversity><racially diverse><research and methods><resistant><response><response to therapy><response to treatment><selection of treatment><skin disorder><social><sound><standard of care><stem and progenitor cell transplantations><theories><therapeutic efficacy><therapeutic response><therapy efficacy><therapy response><therapy selection><transplant><treatment response><treatment responsiveness><treatment selection><treatment strategy><validations>
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Nicole Beaulieu Perez

NEW YORK UNIVERSITY, NEW YORK, NY

Exploratory lead · 42/100
Training-friendly
Active award
Career award
$168,480
FY 2026

Project Title

Reducing Disparities in Mental and Metabolic Health among Predominantly Low-Income, Black and Hispanic Women with and without HIV

Grant Number:

5K08MD019998-03

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/21/2024

End Date:

2/28/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

ABSTRACT In the United States, Black and Hispanic women (BHW) have the greatest risks of poverty, type 2 diabetes (T2D), and depression, problems which represent overlapping and mutually reinforcing epidemics. In the context of HIV, the economic, metabolic, and mental health risks are even greater, ...

Research Terms

<AIDS Virus><Acceleration><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Adult-Onset Diabetes Mellitus><Affect><Aging><Anti-HIV Positivity><Behavioral><Bioinformatics><Biological><Biological Markers><Biology><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Causality><Clinical><Clinical Data><Cohort Studies><Collection><Communities><Critical Paths><Critical Pathways><Cross-Sectional Studies><Cross-Sectional Survey><Data><Data Collection><Decrease disparity><Development><Diagnosis><Disease Frequency Surveys><Disproportionate number of females><Disproportionate number of women><Disproportionately affects females><Disproportionately affects women><Disproportionately impacts females><Disproportionately impacts women><Disproportionately in females><Disproportionately in women><Ecological impact><Economically Deprived><Economics><Emotional Depression><Environmental Factor><Environmental Impact><Environmental Risk Factor><Epidemic><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Ethnic Origin><Ethnicity><Etiology><Exposure to><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Future><GI microbiome><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Grant><HIV><HIV Positive><HIV Positivity><HIV Seroconversion><HIV Seropositivity><HIV antibody positive><HIV disease status><HIV infection status><HIV serostatus><HIV status><HIV+><HIV1 infection status><HIV1 status><HTLV-III Seroconversion><HTLV-III Seropositivity><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Hemoglobin A(1)><Heterogeneity><Hispanic Females><Hispanic Women><Human Immunodeficiency Viruses><Impoverished><Individual><K-Awards><K-Series Research Career Programs><Ketosis-Resistant Diabetes Mellitus><LAV-HTLV-III><Link><Low income><Lower disparity><Lymphadenopathy-Associated Virus><Maps><Maturity-Onset Diabetes Mellitus><Mental Depression><Mental Health><Mental Hygiene><Mentors><Metabolic><Metabolic dysfunction><Methods><Molecular><NCMHD><NIDDM><NIH><NIMH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Mental Health><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Neurobiology><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition><Outcome><Pathway interactions><Poverty><Psyche structure><Psychological Health><Race><Races><Research><Research Career Program><Risk><Risk Factors><Role><Sentinel><Severities><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stress><Symptoms><T2 DM><T2D><T2DM><The Multi-center AIDS Cohort Study><The Multicenter AIDS Cohort Study><Training><Translating><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><United States National Institutes of Health><Variant><Variation><Virus-HIV><Woman><Women's Interagency HIV Study><Women's cohort><Work><accelerated epigenetic age><accelerated epigenetic aging><accelerated pace of epigenetic aging><acceleration in epigenetic age><adult onset diabetes><aging induced epigenetic change><aging-associated epigenetic change><aging-related epigenetic change><alter microbiome><bio-markers><biologic><biologic marker><biomarker><black female><black women><brain based><built environment><causation><co-morbid><co-morbidity><cohort><cohort in women><cohort on women><cohort research study><cohort survey><comorbidity><cross-sectional research study><depression><depression symptom><depressive><depressive symptoms><design><designing><developmental><diagnostic biomarker><diagnostic marker><digestive tract microbiome><disease causation><disparity in health><disparity reduction><early life stress><economic><economic disparity><economically disadvantaged><enteric microbiome><environmental risk><epigenetic aging><epigenetic mechanisms in aging><epigenetic modifications in aging><epigenetic regulation of aging><epigenetically><experience><fMRI><faster epigenetic aging><faster rates of epigenetic aging><female bias><female cohort><female predominance><female preponderance><food insecure><food insecurity><food scarcity><gastrointestinal microbiome><gut microbes><gut microbial species><gut microbiome><gut to brain axis><gut-associated microbiome><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><health disparity><hemoglobin A1c><improved><increased epigenetic age><increased epigenetic aging><increased rates of epigenetic aging><indexing><inflammation marker><inflammatory marker><intestinal biome><intestinal microbes><intestinal microbiome><ketosis resistant diabetes><low SES><low food security><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><maturity onset diabetes><mental><microbiome><microbiome adaptation><microbiome alteration><microbiome perturbation><mitigate disparity><multimorbidity><multiomics><multiple chronic conditions><multiple omics><neural imaging><neuro-imaging><neurobiological><neuroimaging><neurological imaging><panomics><pathway><predominance in females><predominance in women><programs><protective factors><racial><racial background><racial origin><rapid epigenetic aging><reduce disparity><reduction in disparity><social><social culture><social disadvantage><social disparities><social factors><social inequality><social role><social stress><socially stressed><socio-cultural><socio-economic><socio-economically><sociocultural><socioeconomically><socioeconomics><type 2 DM><type II DM><type two diabetes><women's predominance><women's preponderance>
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Gregory Armstrong

ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MEMPHIS, TN

Exploratory lead · 40/100
Solid budget
Recent
Active award
Team-scale grant
$325,043
FY 2026

Project Title

Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS Suppl

Grant Number:

3U24CA055727-32S1

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/20/1993

End Date:

11/30/2026

Project Abstract

ABSTRACT Mach-LETSGO leverages machine learning to improve the accuracy of chronic health condition classification in the Childhood Cancer Survivor Study (CCSS; U24 CA055727; PI: Armstrong), addressing limitations of its self- reported data. By leveraging reference-standard clinical assessments perf...

Research Terms

<21+ years old><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adverse Late Effects><Cancer Survivor><Cancers><Cardiomyopathies><Childhood><Childhood Cancer Survivor Study><Childhood Cancer Treatment><Childhood Cancers><Chronic><Classification><Clinical assessments><Complex><Data><Data Reporting><Demographic Factors><Dependence><Diabetes Mellitus><Ensure><Epidemiologic analysis><Future><Genetic><Genetic Risk><Germ Lines><Health><Hypertension><Intervention><Late Effects><Machine Learning><Malignant Childhood Neoplasm><Malignant Childhood Tumor><Malignant Neoplasms><Malignant Pediatric Neoplasm><Malignant Pediatric Tumor><Malignant Tumor><Malignant childhood cancer><Methodology><Methods><Morbidity><Myocardial Diseases><Myocardial Disorder><Myocardiopathies><Outcome><Participant><Patient Self-Report><Pattern><Pediatric Cancer Treatment><Predictive Cancer Model><Publications><QOL><Quality of life><Reference Standards><Research><Research Resources><Resources><Risk><Saint Jude><Saint Jude Children's Cancer Center><Saint Jude Children's Research Hospital><Scientific Publication><Self-Report><Source><St. Jude><St. Jude Children's Cancer Center><St. Jude Children's Research Hospital><St. Jude Children's Research Hospital Comprehensive Cancer Center><St.Jude Children's Cancer Center><St.Jude Children's Research Hospital><St.Jude Children's Research Hospital Comprehensive Cancer Center><Survey Instrument><Surveys><Survival Rate><Survivors><Systematics><Techniques><Validation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adulthood><cancer in a child><cancer in children><child with cancer><childhood cancer survivor><childhood malignancy><cohort><data representation><data representations><data to train><dataset to train><diabetes><entire genome><epidemiologic evaluation><full genome><genome sequencing><high blood pressure><high risk group><high risk individual><high risk people><high risk population><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><insight><juvenile><juvenile human><machine based learning><machine learning based method><machine learning method><machine learning methodologies><malignancy><mortality><myocardium disease><myocardium disorder><neoplasm/cancer><pediatric><pediatric cancer><pediatric cancer survivor><pediatric malignancy><recommended screening><response><screening guidelines><screening recommendations><survivorship><tool><training data><training datasets><validations><whole genome>
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KELLY KENZIK

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Exploratory lead · 40/100
Solid budget
Very recent
Active award
$324,897
FY 2026

Project Title

Understanding rural mortality disparities in cancer: a multi-level approach

Grant Number:

7R37CA266193-05

Activity Code:

R37

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Cancer mortality rates in the US declined by 26% between 1991 and 2015, but the decline has not been equal across all populations. Approximately 19% of the US population resides in rural areas; for over three decades, this population has experienced increasingly inferior outcomes when compa...

Research Terms

<Access to Care><Address><Application Context><Area><BRFSS><Behavior Risk Factor Surveillance System><Behavioral Risk Factor Surveillance System><Black><Black Populations><Black group><Black individual><Black people><Black race><Blacks><Breast Cancer><Budgets><Cancer Death Rates><Cancer Patient><Cancers><Caring><Censuses><Characteristics><Clinical Trials><Code><Coding System><Commuting><Complex><County><Data><Data Bases><Data Set><Databases><Death Rate><Diagnosis><Disparities><Disparity><ED visit><ER visit><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Evaluation><Excess Mortality><Future><Geographic Area><Geographic Factor><Geographic Locations><Geographic Region><Geographical Location><Geography><HINTS><Health><Health Care><Health Care Providers><Health Information National Trends Survey><Health Insurance><Health Personnel><Health Services Accessibility><Health behavior><Hospital Admission><Hospitalization><Impoverished><Impoverished Areas><Impoverished Regions><Individual><Inferior><Insurance><Intervention><Investigators><Link><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mediating><Mediation><Methodology><Modeling><Nature><Negotiating><Negotiation><Office Management><Outcome><Participant><Play><Policies><Policy Developments><Policy Maker><Population><Poverty><Poverty Areas><Poverty Regions><QOC><Quality of Care><Race><Races><Reasons for Geographic And Racial Differences in Stroke><Reporting><Research Personnel><Researchers><Role><Rural><Rural Population><Rural group><Rural people><SEER Program><SEER-Surveillance, Epidemiology, and End Results><Sampling><Social support><Socio-economic status><Socioeconomic Status><Specialist><Stroke Belt><Surveillance, Epidemiology and End Results><Surveillance, Epidemiology, and End Results Program><System><Transportation><Work><access to health services><access to services><access to treatment><accessibility to health services><availability of services><cancer disparity><cancer health disparity><cancer mortality rate><cancer registry><cancer related death rate><cancer related mortality rate><cancer specific mortality rate><cancer-related health disparity><care access><co-morbid><co-morbidity><cohort><comorbidity><contextual factors><data base><data registry><deprivation><develop therapy><disparities in mortality><disparity in cancer><evidence base><experience><geographic site><health care personnel><health care worker><health insurance plan><health literacy><health provider><health related behavior><health service access><health services availability><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><indexing><intervention development><malignancy><malignant breast tumor><medical care providers><medical personnel><methods to study multiple-level influences><mortality><mortality disparity><mortality rate><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><neoplasm registry><neoplasm/cancer><poverty stricken areas><primary outcome><racial><racial background><racial origin><rural area><rural disparities><rural dwelling><rural households><rural individual><rural location><rural patients><rural poverty><rural region><rural residence><rurality><screening><screenings><service availability><social role><social support network><social vulnerability><socio-demographics><socio-economic position><sociodemographics><socioeconomic position><statistics><therapy development><treatment access><treatment development><treatment provider><urban area><urban disparity><urban location><urban region><urban residence><virtual>
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AARON M MILSTONE

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 38/100
Training-friendly
Solid budget
Active award
$397,203
FY 2025

Project Title

Research Training in Pediatric Infectious Diseases

Grant Number:

5T32AI052071-23

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2002

End Date:

7/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

ABSTRACT The goal of the proposed training program is to continue to provide tailored, strong research skills and knowledge in the discipline of Pediatric Infectious Diseases for physician-scientists pursuing a career in academic Pediatrics. Our proposed training program is multidisciplinary, combin...

Research Terms

<Childhood><Communicable Diseases><Infectious Diseases><Infectious Disorder><Research Training><pediatric>
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Jennifer Rabbitts

STANFORD UNIVERSITY, STANFORD, CA

Exploratory lead · 38/100
Very recent
Active award
Career award
$175,954
FY 2026

Project Title

Preventing the Transition from Acute to Chronic Musculoskeletal Pain in Adolescents after Surgery: The Role of Sleep

Grant Number:

5K24AR080786-05

Activity Code:

K24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/1/2023

End Date:

3/31/2028

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Acute and chronic musculoskeletal (MSK) pain are important health concerns across the lifespan, and surgery is a chief inciting event for subsequent persistent pain. Eighty percent of adolescents undergoing major MSK surgery report severe acute pain, and 20% develop chronic postsurgi...

Research Terms

<12-20 years old><21+ years old><Acceleration><Active Follow-up><Acute><Acute Pain><Acutely painful><Address><Adherence><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Age><Anesthesiology><Anxiety><Applications Grants><Award><Childhood><Chronic><Clinical><Clinical Trials><Collaborations><Complementary intervention><Complementary therapies><Complementary treatment><Data><Dose><Endocrine Gland Secretion><Enrollment><Enteral><Enteric><Epidemic><Event><Fellowship><Funding><Generations><Grant Proposals><Health><Hormones><Intervention><Investigators><K24 Award><K24 Mechanism><K24 Program><Knowledge><Link><Long-term pain><Mediating><Mediator><Medicine><Melatonin><Mentors><Mentorship><Methodology><Methods><Mid-Career Clinical Scientist Award (K24)><Midcareer Investigator Award in Patient-Oriented Research><Midcareer Investigator Award in Patient-Oriented Research (K24)><Modeling><Monitor><Musculoskeletal><Musculoskeletal Pain><NIAMS><National Institute of Arthritis, and Musculoskeletal, and Skin Diseases><Needles><Operative Procedures><Operative Surgical Procedures><Outcome><Pain><Pain Research><Pain intensity><Pain interference><Painful><Parents><Pathway interactions><Perioperative><Persistent pain><Physicians><Population><Post-operative Pain><Postdoc><Postdoctoral Fellow><Postoperative><Postoperative Pain><Postoperative Period><Preventative intervention><Prevention><Psychophysics><Puberty><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reporting><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Support><Researchers><Risk><Risk Factors><Risk Marker><Role><Safety><Science><Scientist><Sleep><Sleep Wake Cycle><Sleep disturbances><Spinal Fusion><Spinal surgery><Spine surgery><Spondylosyndeses><Surgical><Surgical Interventions><Surgical Procedure><Teen><Teenagers><Testing><Time><Training><Training Programs><Universities><Washington><Youth><Youth 10-21><aberrant sleep><acceptability and feasibility><active followup><acute to chronic pain transition><adolescence (12-20)><adulthood><ages><assess effectiveness><associate faculty><associate professor><biopsychosocial><career><chronic MSK pain><chronic musculoskeletal pain><chronic pain><chronic pain transition><clinical pain><cohort><constant pain><determine effectiveness><disrupted sleep><disturbed sleep><effectiveness assessment><effectiveness evaluation><efficacy testing><efficacy trial><enroll><evaluate effectiveness><examine effectiveness><experience><feasibility trial><fibromyalgia patients><follow up><follow-up><followed up><followup><forging><health goals><health related quality of life><high risk><impaired sleep><improved><improvement on sleep><innovate><innovation><innovative><intervention for prevention><irregular sleep><juvenile><juvenile human><lasting pain><life span><lifespan><longitudinal design><longitudinal experimental design><longitudinal research design><longitudinal study design><m-Health><mHealth><malleable risk><mid-career faculty><midcareer faculty><minimal risk><mobile health><modifiable risk><next generation><non-narcotic analgesic><non-opiate analgesic><non-opioid><non-opioid analgesic><non-opioid therapeutics><nonnarcotic analgesics><nonopiate analgesic><nonopioid><nonopioid analgesics><novel><on-going pain><ongoing pain><pain after surgery><pain chronification><pain processing><pain reduction><pain sensitivity><parent><pathway><patient centered><patient oriented><patients with fibromyalgia><pediatric><pilot trial><poor health outcome><post-doc><post-doctoral><post-doctoral trainee><post-surgical pain><postsurgical pain><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary outcome><programs><psychophysical><psychosocial><quality of sleep><reduce pain><reduced health outcome><research associates><research study><resilience><resilience factor><resiliency factor><resilient><risk predictor><risk predictors><secondary outcome><sensory mechanism><sex><side effect><skills><sleep amount><sleep control><sleep disruption><sleep duration><sleep dysregulation><sleep episode><sleep improvement><sleep interval><sleep length><sleep period><sleep quality><sleep quantity><sleep regulation><sleep time><sleep to wake transition><sleep to wakefulness transition><sleep wakefulness cycle><sleep/wake disruption><sleep/wake disturbance><sleep/wake regulation><sleep/wake transitions><social role><surgery><teen years><teenage><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><training opportunity><transition to chronic pain><worse health outcome><youth age>
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Natalia E. Morone

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$810,528
FY 2025

Project Title

Creating Opportunities for Unparalleled Researchers to Achieve Growth and Excellence (COURAGE)

Grant Number:

5U24DK132733-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/15/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Obesity, nutrition, and diabetes are major areas of need for biomedical research in the United States as the prevalence of obesity and associated comorbidities – including cardiovascular disease and cancer – remains high. Early career researchers in these areas face multiple challenges in establishi...

Research Terms

<Academia><Address><Applications Grants><Area><Award><Biomedical Research><Boston><Budgets><Cancers><Cardiovascular Diseases><Career Choice><Career Mobility><Career Path><Chronic Disease><Chronic Illness><Collaborations><Communities><Complex><Country><Curriculum><Data Analyses><Data Analysis><Development Plans><Diabetes Mellitus><Discipline><Disease><Disorder><Educational Curriculum><Educational workshop><Epidemiologist><Face><Faculty><Generalized Growth><Goals><Grant><Grant Proposals><Growth><Individual><Institution><Intervention><Investigators><Lead><Leadership><Learning Skill><Malignant Neoplasms><Malignant Tumor><Manuscripts><Mediation><Medicine><Mentors><Mentorship><Modeling><Morones><NIH><National Institutes of Health><Negotiating><Negotiation><Nutrition><Obesity><Participant><Pb element><Persons><Phase><Pilot Projects><Postdoc><Postdoctoral Fellow><Preparation><Prevalence><Productivity><Program Development><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Scientific Publication><Scientist><Self Assessment><Series><Site><Talents><Testing><Time Management><Tissue Growth><Training><United States><United States National Institutes of Health><Universities><Work><Workshop><Writing><adiposity><cardiovascular disorder><career><career advancement><career aspiration><career development><career interest><career pathway><career track><career transition><chronic disorder><co-morbid><co-morbidity><cohort><college><collegiate><comorbidity><corpulence><data interpretation><diabetes><experience><faces><facial><faculty mentor><full professor><graduate school><heavy metal Pb><heavy metal lead><high school><interest><leadership development><lesson plans><malignancy><meeting><meetings><neoplasm/cancer><ontogeny><peer><peer coaching><peer instruction><peer led team learning><peer mentoring><peer networks><peer teaching><pilot study><post-doc><post-doctoral><post-doctoral trainee><preparations><programs><recruit><research associates><senior faculty><skills><success>
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Fatima Cody Stanford

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$810,528
FY 2025

Project Title

Creating Opportunities for Unparalleled Researchers to Achieve Growth and Excellence (COURAGE)

Grant Number:

5U24DK132733-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/15/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Obesity, nutrition, and diabetes are major areas of need for biomedical research in the United States as the prevalence of obesity and associated comorbidities – including cardiovascular disease and cancer – remains high. Early career researchers in these areas face multiple challenges in establishi...

Research Terms

<Academia><Address><Applications Grants><Area><Award><Biomedical Research><Boston><Budgets><Cancers><Cardiovascular Diseases><Career Choice><Career Mobility><Career Path><Chronic Disease><Chronic Illness><Collaborations><Communities><Complex><Country><Curriculum><Data Analyses><Data Analysis><Development Plans><Diabetes Mellitus><Discipline><Disease><Disorder><Educational Curriculum><Educational workshop><Epidemiologist><Face><Faculty><Generalized Growth><Goals><Grant><Grant Proposals><Growth><Individual><Institution><Intervention><Investigators><Lead><Leadership><Learning Skill><Malignant Neoplasms><Malignant Tumor><Manuscripts><Mediation><Medicine><Mentors><Mentorship><Modeling><Morones><NIH><National Institutes of Health><Negotiating><Negotiation><Nutrition><Obesity><Participant><Pb element><Persons><Phase><Pilot Projects><Postdoc><Postdoctoral Fellow><Preparation><Prevalence><Productivity><Program Development><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Scientific Publication><Scientist><Self Assessment><Series><Site><Talents><Testing><Time Management><Tissue Growth><Training><United States><United States National Institutes of Health><Universities><Work><Workshop><Writing><adiposity><cardiovascular disorder><career><career advancement><career aspiration><career development><career interest><career pathway><career track><career transition><chronic disorder><co-morbid><co-morbidity><cohort><college><collegiate><comorbidity><corpulence><data interpretation><diabetes><experience><faces><facial><faculty mentor><full professor><graduate school><heavy metal Pb><heavy metal lead><high school><interest><leadership development><lesson plans><malignancy><meeting><meetings><neoplasm/cancer><ontogeny><peer><peer coaching><peer instruction><peer led team learning><peer mentoring><peer networks><peer teaching><pilot study><post-doc><post-doctoral><post-doctoral trainee><preparations><programs><recruit><research associates><senior faculty><skills><success>
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Takara Leah Stanley

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$810,528
FY 2025

Project Title

Creating Opportunities for Unparalleled Researchers to Achieve Growth and Excellence (COURAGE)

Grant Number:

5U24DK132733-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/15/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Obesity, nutrition, and diabetes are major areas of need for biomedical research in the United States as the prevalence of obesity and associated comorbidities – including cardiovascular disease and cancer – remains high. Early career researchers in these areas face multiple challenges in establishi...

Research Terms

<Academia><Address><Applications Grants><Area><Award><Biomedical Research><Boston><Budgets><Cancers><Cardiovascular Diseases><Career Choice><Career Mobility><Career Path><Chronic Disease><Chronic Illness><Collaborations><Communities><Complex><Country><Curriculum><Data Analyses><Data Analysis><Development Plans><Diabetes Mellitus><Discipline><Disease><Disorder><Educational Curriculum><Educational workshop><Epidemiologist><Face><Faculty><Generalized Growth><Goals><Grant><Grant Proposals><Growth><Individual><Institution><Intervention><Investigators><Lead><Leadership><Learning Skill><Malignant Neoplasms><Malignant Tumor><Manuscripts><Mediation><Medicine><Mentors><Mentorship><Modeling><Morones><NIH><National Institutes of Health><Negotiating><Negotiation><Nutrition><Obesity><Participant><Pb element><Persons><Phase><Pilot Projects><Postdoc><Postdoctoral Fellow><Preparation><Prevalence><Productivity><Program Development><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Scientific Publication><Scientist><Self Assessment><Series><Site><Talents><Testing><Time Management><Tissue Growth><Training><United States><United States National Institutes of Health><Universities><Work><Workshop><Writing><adiposity><cardiovascular disorder><career><career advancement><career aspiration><career development><career interest><career pathway><career track><career transition><chronic disorder><co-morbid><co-morbidity><cohort><college><collegiate><comorbidity><corpulence><data interpretation><diabetes><experience><faces><facial><faculty mentor><full professor><graduate school><heavy metal Pb><heavy metal lead><high school><interest><leadership development><lesson plans><malignancy><meeting><meetings><neoplasm/cancer><ontogeny><peer><peer coaching><peer instruction><peer led team learning><peer mentoring><peer networks><peer teaching><pilot study><post-doc><post-doctoral><post-doctoral trainee><preparations><programs><recruit><research associates><senior faculty><skills><success>
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Jiang Bian

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$801,896
FY 2025

Project Title

ACCELERATE-BASSO: Coordinating Center for Accelerating Behavioral and Social Science through Ontology

Grant Number:

7U24AG088019-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/20/2024

End Date:

5/31/2029

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT An individual’s phenotypes related to their health conditions are associated with the complex interplay between the individual’s biological, behavioral, social, and environmental processes, including phenomena that occur both within (e.g., genetics, emotion, cognition) and external (e.g., s...

Research Terms

<Acceleration><Address><Adopted><Behavioral><Biological><Body Build><Body Types><Classification><Cognition><Collaborations><Communities><Complex><Consensus><Development><Discipline><Emotions><Engineering><Environment><Evaluation><FAIR data><FAIR guiding principles><FAIR principles><Face><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Genetic><Health><Individual><Informatics><Information Resources><Infrastructure><Institution><Knowledge><Learning><Legal><Licensing><Life Cycle><Life Cycle Stages><Maintenance><Manuals><Medicine><Modeling><NIH><National Academy of Sciences><National Institutes of Health><Ontology><Organism><Phenotype><Plug-in><Policies><Procedures><Process><Professional Organizations><R-Series Research Projects><R01 Mechanism><R01 Program><Recommendation><Records><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Resource Sharing><Resources><Science><Somatotype><Spinal Column><Spine><Standardization><System><Systematics><Technology><Training><United States National Academy of Sciences><United States National Institutes of Health><Vertebral column><Visualization><backbone><behavior study><behavioral and social science><behavioral study><biologic><biomedical ontology><data sharing networks><data sharing resource><depository><design><designing><developmental><efficacious intervention><faces><facial><health science research><improved><informatics tool><information resource><knowledge resource><knowledge resources><life course><living system><member><multidisciplinary><ontology development><operation><operations><outreach><professional association><professional membership><professional society><programs><repository><response><social><social science research><success><tool><tool development><user-friendly><work group><working group>
View Full Project Details on NIH Reporter
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Mark A Musen

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$801,896
FY 2025

Project Title

ACCELERATE-BASSO: Coordinating Center for Accelerating Behavioral and Social Science through Ontology

Grant Number:

7U24AG088019-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/20/2024

End Date:

5/31/2029

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT An individual’s phenotypes related to their health conditions are associated with the complex interplay between the individual’s biological, behavioral, social, and environmental processes, including phenomena that occur both within (e.g., genetics, emotion, cognition) and external (e.g., s...

Research Terms

<Acceleration><Address><Adopted><Behavioral><Biological><Body Build><Body Types><Classification><Cognition><Collaborations><Communities><Complex><Consensus><Development><Discipline><Emotions><Engineering><Environment><Evaluation><FAIR data><FAIR guiding principles><FAIR principles><Face><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Genetic><Health><Individual><Informatics><Information Resources><Infrastructure><Institution><Knowledge><Learning><Legal><Licensing><Life Cycle><Life Cycle Stages><Maintenance><Manuals><Medicine><Modeling><NIH><National Academy of Sciences><National Institutes of Health><Ontology><Organism><Phenotype><Plug-in><Policies><Procedures><Process><Professional Organizations><R-Series Research Projects><R01 Mechanism><R01 Program><Recommendation><Records><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Resource Sharing><Resources><Science><Somatotype><Spinal Column><Spine><Standardization><System><Systematics><Technology><Training><United States National Academy of Sciences><United States National Institutes of Health><Vertebral column><Visualization><backbone><behavior study><behavioral and social science><behavioral study><biologic><biomedical ontology><data sharing networks><data sharing resource><depository><design><designing><developmental><efficacious intervention><faces><facial><health science research><improved><informatics tool><information resource><knowledge resource><knowledge resources><life course><living system><member><multidisciplinary><ontology development><operation><operations><outreach><professional association><professional membership><professional society><programs><repository><response><social><social science research><success><tool><tool development><user-friendly><work group><working group>
View Full Project Details on NIH Reporter
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Cui Tao

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$801,896
FY 2025

Project Title

ACCELERATE-BASSO: Coordinating Center for Accelerating Behavioral and Social Science through Ontology

Grant Number:

7U24AG088019-02

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/20/2024

End Date:

5/31/2029

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT An individual’s phenotypes related to their health conditions are associated with the complex interplay between the individual’s biological, behavioral, social, and environmental processes, including phenomena that occur both within (e.g., genetics, emotion, cognition) and external (e.g., s...

Research Terms

<Acceleration><Address><Adopted><Behavioral><Biological><Body Build><Body Types><Classification><Cognition><Collaborations><Communities><Complex><Consensus><Development><Discipline><Emotions><Engineering><Environment><Evaluation><FAIR data><FAIR guiding principles><FAIR principles><Face><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Genetic><Health><Individual><Informatics><Information Resources><Infrastructure><Institution><Knowledge><Learning><Legal><Licensing><Life Cycle><Life Cycle Stages><Maintenance><Manuals><Medicine><Modeling><NIH><National Academy of Sciences><National Institutes of Health><Ontology><Organism><Phenotype><Plug-in><Policies><Procedures><Process><Professional Organizations><R-Series Research Projects><R01 Mechanism><R01 Program><Recommendation><Records><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Resource Sharing><Resources><Science><Somatotype><Spinal Column><Spine><Standardization><System><Systematics><Technology><Training><United States National Academy of Sciences><United States National Institutes of Health><Vertebral column><Visualization><backbone><behavior study><behavioral and social science><behavioral study><biologic><biomedical ontology><data sharing networks><data sharing resource><depository><design><designing><developmental><efficacious intervention><faces><facial><health science research><improved><informatics tool><information resource><knowledge resource><knowledge resources><life course><living system><member><multidisciplinary><ontology development><operation><operations><outreach><professional association><professional membership><professional society><programs><repository><response><social><social science research><success><tool><tool development><user-friendly><work group><working group>
View Full Project Details on NIH Reporter
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Ann Laura Oberg

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$659,850
FY 2025

Project Title

Management and Data Coordination Unit for PCDC

Grant Number:

5U24CA274496-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, partially owing to lack of effective biomarkers and/or screening strategies. The 5-year survival of patients with localized PDAC is 39% compared to 3% in patients diagnosed with metastatic disease, which indicates tha...

Research Terms

<Adherence><Administrative Coordination><Biological Markers><Biometrics><Biometry><Biostatistics><Blinded><Cancer Detection><Cancers><Clinic><Collaborations><Communication><Communities><Consultations><Data><Data Analyses><Data Analysis><Data Bases><Data Collection><Data Management Core><Databases><Development><Diagnosis><Disease><Disorder><Documentation><Early Diagnosis><Early Intervention><Educational workshop><Enrollment><Ensure><Evaluation Studies><Experimental Designs><Future><Goals><Grant><Human Resources><IRB><IRBs><Infrastructure><Institution><Institutional Review Boards><Investigators><Knowledge><Lead><Leadership><Lesion><Logistics><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant neoplasm of pancreas><Manpower><Monitor><NIH><National Institutes of Health><Pancreas Cancer><Pancreas Ductal Adenocarcinoma><Pancreatic Cancer><Pancreatic Ductal Adenocarcinoma><Participant><Patient Recruitments><Patients><Pb element><Phase><Policies><Population><Procedures><Process><Protocol><Protocols documentation><Randomized><Reproducibility><Research><Research Design><Research Personnel><Research Resources><Researchers><Resources><Role><Sampling><Secure><Site><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Strategic Planning><Study Type><Testing><Time><Triage><United States National Institutes of Health><Update><Validation><Work><Workshop><bio-markers><biobank><biologic marker><biomarker><biomarker discovery><biomarker validation><biorepository><case control><case-controlled><clinical relevance><clinically relevant><cohort><conference><consultation><convention><data base><data handling><data interpretation><data management><data management and coordinating center><data management center><depository><developmental><early biomarkers><early detection><early detection biomarkers><early detection markers><enroll><experience><heavy metal Pb><heavy metal lead><high risk><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><innovate><innovation><innovative><malignancy><marker validation><meeting><meetings><molecular biomarker><molecular marker><multidisciplinary><neoplasm/cancer><pancreatic malignancy><participant recruitment><personnel><programs><progression risk><prospective><protocol development><randomisation><randomization><randomly assigned><repository><research study><sample collection><screening><screenings><social role><specimen collection><statistical analysis><study design><summit><symposia><symposium><tool><validations><virtual>
View Full Project Details on NIH Reporter
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Robert Richard Freimuth

MAYO CLINIC JACKSONVILLE, JACKSONVILLE, FL

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$554,405
FY 2025

Project Title

The Data, Evaluation, and Coordination Center (DECC) for Connecting Underrepresented Populations to Clinical Trials (CUSP2CT)

Grant Number:

5U24CA277825-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/16/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Despite the decline in overall mortality and incidence of cancer in the US population, the burden of cancer care is still high. One key barrier experienced by those that have high burden of cancer is the lack of dedicated efforts employing scientifically rigorous approaches and implementation strate...

Research Terms

<Administrative Efficiency><Adopted><Award><Benchmarking><Best Practice Analysis><Cancer Burden><Cancers><Caring><Center for Cancer Research><Clinical Data><Clinical Trials><Collaborations><Common Data Element><Communication><Communities><Consensus><Data><Data Analytics><Data Collection><Data Management Core><Data Pooling><Data Science><Dedications><Department of Defense><Development><Discipline><Education and Outreach><Education for Intervention><Educational Intervention><Enrollment><Ethics><Evaluation><Fostering><Generations><Goals><Grant><Health><Human><Incidence><Infrastructure><Institution><Instruction Intervention><Instruction and Outreach><Intervention><Investigators><Leadership><Learning><Logistics><Malignant Neoplasms><Malignant Tumor><Manuscripts><Measures><Methods><Mission><Modern Man><NCATS><NCI Center for Cancer Research><National Cancer Burden><National Center for Advancing Translational Sciences><Oncology><Oncology Cancer><Outcome><Participant><Patients><Policies><Population><Position><Positioning Attribute><Procedures><Process><Program Evaluation><Protocol><Protocols documentation><Publications><Recommendation><Reporting><Research><Research Activity><Research Design><Research Personnel><Research Resources><Research Support><Researchers><Resources><Science><Scientific Publication><Secure><Services><Site><Standardization><Structure><Study Type><Terminology><Training Intervention><Training and Outreach><Tutoring and Outreach><Underrepresented Groups><Underrepresented Populations><Work><benchmark><cancer care><clinical trial participant><data exchange><data harmonization><data management><data management and coordinating center><data management center><data sharing><data transfer><data transmission><developmental><enroll><ethical><evidence base><experience><harmonized data><implementation strategy><instructional intervention><internet portal><interoperability><malignancy><meeting><meetings><member><mortality><neoplasm/cancer><on-line portal><online portal><operation><operations><patient population><privacy preservation><programs><social media><statistics><strategies for implementation><study design><tool><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><web portal><web-based portal>
View Full Project Details on NIH Reporter
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Jennifer G. Le-Rademacher

MAYO CLINIC JACKSONVILLE, JACKSONVILLE, FL

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$554,405
FY 2025

Project Title

The Data, Evaluation, and Coordination Center (DECC) for Connecting Underrepresented Populations to Clinical Trials (CUSP2CT)

Grant Number:

5U24CA277825-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/16/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Despite the decline in overall mortality and incidence of cancer in the US population, the burden of cancer care is still high. One key barrier experienced by those that have high burden of cancer is the lack of dedicated efforts employing scientifically rigorous approaches and implementation strate...

Research Terms

<Administrative Efficiency><Adopted><Award><Benchmarking><Best Practice Analysis><Cancer Burden><Cancers><Caring><Center for Cancer Research><Clinical Data><Clinical Trials><Collaborations><Common Data Element><Communication><Communities><Consensus><Data><Data Analytics><Data Collection><Data Management Core><Data Pooling><Data Science><Dedications><Department of Defense><Development><Discipline><Education and Outreach><Education for Intervention><Educational Intervention><Enrollment><Ethics><Evaluation><Fostering><Generations><Goals><Grant><Health><Human><Incidence><Infrastructure><Institution><Instruction Intervention><Instruction and Outreach><Intervention><Investigators><Leadership><Learning><Logistics><Malignant Neoplasms><Malignant Tumor><Manuscripts><Measures><Methods><Mission><Modern Man><NCATS><NCI Center for Cancer Research><National Cancer Burden><National Center for Advancing Translational Sciences><Oncology><Oncology Cancer><Outcome><Participant><Patients><Policies><Population><Position><Positioning Attribute><Procedures><Process><Program Evaluation><Protocol><Protocols documentation><Publications><Recommendation><Reporting><Research><Research Activity><Research Design><Research Personnel><Research Resources><Research Support><Researchers><Resources><Science><Scientific Publication><Secure><Services><Site><Standardization><Structure><Study Type><Terminology><Training Intervention><Training and Outreach><Tutoring and Outreach><Underrepresented Groups><Underrepresented Populations><Work><benchmark><cancer care><clinical trial participant><data exchange><data harmonization><data management><data management and coordinating center><data management center><data sharing><data transfer><data transmission><developmental><enroll><ethical><evidence base><experience><harmonized data><implementation strategy><instructional intervention><internet portal><interoperability><malignancy><meeting><meetings><member><mortality><neoplasm/cancer><on-line portal><online portal><operation><operations><patient population><privacy preservation><programs><social media><statistics><strategies for implementation><study design><tool><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><web portal><web-based portal>
View Full Project Details on NIH Reporter
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FOLAKEMI T ODEDINA

MAYO CLINIC JACKSONVILLE, JACKSONVILLE, FL

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$554,405
FY 2025

Project Title

The Data, Evaluation, and Coordination Center (DECC) for Connecting Underrepresented Populations to Clinical Trials (CUSP2CT)

Grant Number:

5U24CA277825-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/16/2022

End Date:

8/31/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Despite the decline in overall mortality and incidence of cancer in the US population, the burden of cancer care is still high. One key barrier experienced by those that have high burden of cancer is the lack of dedicated efforts employing scientifically rigorous approaches and implementation strate...

Research Terms

<Administrative Efficiency><Adopted><Award><Benchmarking><Best Practice Analysis><Cancer Burden><Cancers><Caring><Center for Cancer Research><Clinical Data><Clinical Trials><Collaborations><Common Data Element><Communication><Communities><Consensus><Data><Data Analytics><Data Collection><Data Management Core><Data Pooling><Data Science><Dedications><Department of Defense><Development><Discipline><Education and Outreach><Education for Intervention><Educational Intervention><Enrollment><Ethics><Evaluation><Fostering><Generations><Goals><Grant><Health><Human><Incidence><Infrastructure><Institution><Instruction Intervention><Instruction and Outreach><Intervention><Investigators><Leadership><Learning><Logistics><Malignant Neoplasms><Malignant Tumor><Manuscripts><Measures><Methods><Mission><Modern Man><NCATS><NCI Center for Cancer Research><National Cancer Burden><National Center for Advancing Translational Sciences><Oncology><Oncology Cancer><Outcome><Participant><Patients><Policies><Population><Position><Positioning Attribute><Procedures><Process><Program Evaluation><Protocol><Protocols documentation><Publications><Recommendation><Reporting><Research><Research Activity><Research Design><Research Personnel><Research Resources><Research Support><Researchers><Resources><Science><Scientific Publication><Secure><Services><Site><Standardization><Structure><Study Type><Terminology><Training Intervention><Training and Outreach><Tutoring and Outreach><Underrepresented Groups><Underrepresented Populations><Work><benchmark><cancer care><clinical trial participant><data exchange><data harmonization><data management><data management and coordinating center><data management center><data sharing><data transfer><data transmission><developmental><enroll><ethical><evidence base><experience><harmonized data><implementation strategy><instructional intervention><internet portal><interoperability><malignancy><meeting><meetings><member><mortality><neoplasm/cancer><on-line portal><online portal><operation><operations><patient population><privacy preservation><programs><social media><statistics><strategies for implementation><study design><tool><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><web portal><web-based portal>
View Full Project Details on NIH Reporter
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Shijing Jia

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 36/100
Training-friendly
Active award
Career award
$195,459
FY 2025

Project Title

Iron Deficiency in Cystic Fibrosis: Characterization of Clinical Impact and Treatment Effects

Grant Number:

1K23HL175126-01A1

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/1/2025

End Date:

7/31/2030

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Shijing Jia, MD, is a Pulmonary and Critical Care physician at the University of Michigan. This K23 mentored career development application includes a coordinated 5-year plan of training and research activities designed to advance Dr. Jia toward her long-term goal of becoming an ind...

Research Terms

<Achievement><Achievement Attainment><Affect><Anemia><Biological Markers><Biometrics><Biometry><Biostatistics><Blood Serum><Bowel Obstruction><CD71><CF patients><Cardiac Failure Congestive><Cessation of life><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Chronic lung disease><Clinical><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Design><Cohort Studies><Complement><Complement Proteins><Complication><Concurrent Studies><Congestive Heart Failure><Critical Care><Cystic Fibrosis><Data><Data Bases><Data Science><Databases><Death><Dedications><Development><Diagnosis><Diagnostic><Discipline><Disease><Disorder><Effectiveness><Ensure><Ethnic Origin><Ethnicity><Event><Evidence based practice guidelines><Fatigue><Fe deficiency><Fe element><Ferritin><Future><General Population><General Public><Genetic Diseases><Goals><Guidelines><Heart Decompensation><Hemoglobin><High Prevalence><Hospital Admission><Hospitalization><Inflammation><Inflammatory><Inflammatory Bowel Diseases><Inflammatory Bowel Disorder><Intestinal Obstruction><Intravenous><Investigators><Iron><Knowledge><Lack of Energy><Lead><Life Expectancy><Link><Long-term infection><Lung><Lung Diseases><Lung Respiratory System><Lung infections><Master of Science><Master's Degree><Measures><Mentors><Mentorship><Michigan><Modernization><Morbidity><Morbidity - disease rate><Mucoviscidosis><Oral><Outcome><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Pb element><Persons><Physicians><Pilot Projects><Pneumology><Pneumonology><Population><Prevalence><Provider><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Medicine><Pulmonology><Questionnaires><Race><Races><Randomization trial><Randomized><Randomized, Controlled Trials><Recommendation><Recurrence><Recurrent><Reporting><Research><Research Activity><Research Infrastructure><Research Personnel><Research Resources><Researchers><Resources><Retrospective cohort study><Risk><Scientist><Seminal><Serum><Severities><Siderophilin><Site><Subgroup><TFR gene><TFR protein><TFR1><TFRC><TFRC gene><TRFR><Training><Training Activity><Training Programs><Transferrin><Transferrin Receptor><Transferrin Receptor 1><Treatment Efficacy><Treatment outcome><Universities><Walking><Work><World Health Organization><bio-markers><biologic marker><biomarker><career development><chronic heart failure><chronic infection><chronic inflammatory disease><chronic kidney disease><chronic pulmonary disease><clinical efficacy><clinical relevance><clinically relevant><co-morbid><co-morbidity><comorbidity><comparable efficacy><comparative><comparative efficacy><comparative safety><comparative treatment><compare efficacy><complementation><cystic fibrosis patients><data base><design><designing><developmental><diagnostic criteria><disease of the lung><disorder of the lung><evidence based guidelines><evidence based recommendations><experience><functional status><gastrointestinal><genetic condition><genetic disorder><heavy metal Pb><heavy metal lead><improved><indexing><individualized management><individualized patient management><individuals with CF><individuals with cystic fibrosis><inflammatory disease of the intestine><inflammatory disorder of the intestine><intervention efficacy><intestinal autoinflammation><intestine obstruction><iron deficiency><lung disorder><lung function><mortality><patient oriented research><patient oriented study><patient population><patients with CF><patients with cystic fibrosis><persistent infection><personalized clinical management><personalized diagnosis><personalized diagnostics><personalized disease management><personalized management><pilot study><pilot trial><precise diagnostics><precision diagnostics><precision management><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><pulmonary><pulmonary function><pulmonary infections><racial><racial background><racial origin><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><routine care><side effect><specific biomarkers><success><therapeutic efficacy><therapy efficacy><training module><treatment effect><treatment guidelines>
View Full Project Details on NIH Reporter
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Martha Skiles

WASHINGTON STATE DEPARTMENT OF HEALTH, TUMWATER, WA

Exploratory lead · 34/100
Likely hiring
Team-scale grant
$175,000
FY 2025

Project Title

RFA-DP-22-001 DP006601 Component A - Core Surveillance - Washington Pregnancy Risk Assessment Monitoring System (PRAMS) RFA-DP-16-001

Grant Number:

5U01DP006601-05

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

ALLCDC

Start Date:

5/1/2021

End Date:

4/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Washington State PRAMS Core Grant –Component A Project Summary/Abstract PRAMS 2021 Grant Project Title: Pregnancy Risk Assessment Monitoring System (PRAMS) (U01) Category B. (Existing States) Washington State PRAMS 2021 Project Director: Teresa Vollan, PI/PD Address: Washington State Department of H...

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Jeong Ho Kim

TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, COLLEGE STATION, TX

Exploratory lead · 34/100
Likely hiring
Team-scale grant
$118,268
FY 2025

Project Title

Commercial Fishing Occupational Safety Research Cooperative Agreement (U01) - 2022

Grant Number:

1U01OH012969-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

ALLCDC

Start Date:

9/1/2021

End Date:

8/31/2025

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
View Full Project Details on NIH Reporter
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Larissa Benjamin

UNIVERSITY OF CALIFORNIA BERKELEY, BERKELEY, CA

Exploratory lead · 34/100
Training-friendly
Active award
$47,105
FY 2026

Project Title

Understanding the Macrosocial Drivers of Cardiovascular Health in the Rural South

Grant Number:

5F31MD020261-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

11/1/2024

End Date:

10/31/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary Rural Americans currently face a significant health crisis marked by a heightened prevalence of cardiovascular disease (CVD), the leading cause of mortality in the United States, responsible for one-third of all deaths and claiming a life every 34 seconds. Although this rural health ...

Research Terms

<21+ years old><Accounting><Address><Adult><Adult Human><Affect><Age><Alabama><Appalachia><Appalachian><Appalachian Region><Area><Automobile Driving><Black><Black race><Blood Pressure><Cardiovascular Diseases><Censuses><Cessation of life><Complex><Data><Death><Delta Region of Mississippi><Diabetes Mellitus><Disparities><Disparity><Economics><Environment><Environmental Pollution><Ethnic Group><Ethnic Origin><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity><Ethnicity People><Ethnicity Population><Face><Fellowship><Goals><Health><Health Inequity><High Prevalence><Impoverished><Incidence><Individual><Inequalities in Health><Inequities in Health><Inequity><Injury><Kentucky><Knowledge><Life><Link><Longitudinal Studies><Longitudinal Surveys><Louisiana><Measures><Mentorship><Mississippi><Mississippi Delta><Natural Disasters><Nature><Neighborhoods><Obesity><Outcome><Persons><Phase><Population><Poverty><Prevalence><Process><Public Health Practice><Public Health Schools><Race><Races><Research><Risk><Risk Factors><Role><Rural><Rural Community><Rural Health><SES disparity><Shapes><Social isolation><Socio-economic status><Socioeconomic Status><Stress><Stroke Belt><United States><Variant><Variation><Work><adiposity><adulthood><aged><ages><cardiometabolic><cardiometabolism><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><career><cohort><corpulence><deprivation><diabetes><disparities in race><disparity due to race><disparity in ethnic><driving><economic><environmental contamination><ethnic based disparity><ethnic disadvantage><ethnic disparity><ethnic inequality><ethnic inequity><ethnic subgroup><ethnicity disparity><ethnicity group><faces><facial><health equity><health inequalities><indexing><inequality due to race><inequity due to race><injuries><long-term study><longitudinal outcome studies><longitudinal research study><mortality><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial><racial background><racial disparity><racial inequality><racial inequity><racial minority group><racial minority individual><racial minority people><racial minority population><racial origin><racially unequal><recruit><residence><residential building><residential segregation><residential site><rural Americans><rural area><rural counties><rural dwelling><rural households><rural location><rural region><rural residence><rurality><segregation><social><social health determinants><social role><social vulnerability><socio-economic><socio-economic disparity><socio-economic inequality><socio-economic inequity><socio-economic position><socio-economically><socioeconomic disparity><socioeconomic inequality><socioeconomic inequity><socioeconomic position><socioeconomically><socioeconomics><urban area><urban environment><urban location><urban region><urban setting>
View Full Project Details on NIH Reporter
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Hayden B Bosworth

DURHAM VA MEDICAL CENTER, DURHAM, NC

Exploratory lead · 30/100
Very recent
Active award
$0
FY 2026

Project Title

HSR&D Senior Research Career Scientist Award

Grant Number:

5IK6HX003161-07

Activity Code:

IK6

Mechanism:

Other

Agency:

VA

Start Date:

4/1/2020

End Date:

2/28/2027

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

This renewal of a Senior Research Career Scientist (SRCS) award is to support Dr. Hayden Bosworth to further provide scientific, mentoring and service contributions to Veterans. Dr. Bosworth’s main research interests comprise 3 overarching areas that align with VA HSR&D and the VA secretary’s top pr...

Research Terms

<AIDS Virus><AIDS focused research><AIDS related research><AIDS research><AIDS science><AIDS specific research><Access to Care><Achievement><Achievement Attainment><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Adherence><Adoption><Aging><American Heart Association><Analgesic Management><Apoplexy><Area><Award><Behavior><Books><Brain Vascular Accident><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic><Chronic Care><Chronic Disease><Chronic Illness><Circulation><Clinical><Clinical Trials><Collaborations><Communication><Computerized Medical Record><Counseling><Curriculum><De-implementation><Dedications><Deimplementation><Development><Doctor of Philosophy><Educational Curriculum><Educational process of instructing><Effectiveness><Effectiveness of Interventions><Electronic Medical Record><Enrollment><Ensure><Evaluation><Faculty><Focus Groups><Foundations><Funding><Goals><Grant><Guidelines><HINTS><HIV><HIV focused research><HIV investigation><HIV related research><HIV research><HIV science><HIV specific research><Health Care Systems><Health Information National Trends Survey><Health Sciences><Health Services><Health Services Accessibility><Health Services Evaluation><Health Services Research><Health system><Heart Vascular><Heterogeneity><Home><Homogeneously Staining Region><Human Immunodeficiency Viruses><Hypertension><Improve Access><Individual><Industry><International><Intervention><Intervention Studies><Investigation on HIV><Investigator-Initiated Research><Investigators><K-Awards><K-Series Research Career Programs><K12><K12 Award><K12 Mechanism><K12 Program><Knowledge><LAV-HTLV-III><Lead><Leadership><Legislation><Low Literacy Population><Lymphadenopathy-Associated Virus><Medicaid><Medical Care Research><Medication Management><Mentored Clinical Scientist Development Program><Mentors><Mentorship><Meta-Analysis><Methodology><Methods><Mission><Modeling><Monitor><NHLBI><NIH><National Heart, Lung, and Blood Institute><National Institutes of Health><North Carolina><Outcome><Paper><Patient Education><Patient Instruction><Patient Training><Patient-Centered Care><Patients><Pb element><Peer Review><Ph.D.><PhD><Pharmacists><Pharmacologic Management><Population><Postdoc><Postdoctoral Fellow><Preventative care><Preventive care><Primary Care><Principal Investigator><Program Appropriateness><Provider><Publications><Publishing><QOC><Qualitative Methods><Quality of Care><R-Series Research Projects><R01 Mechanism><R01 Program><Recommendation><Reporting><Research><Research Associate><Research Career Program><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Risk><Risk Management><Risk Reduction><Role><Rural><Rural Health><Scholars Program><Scientific Publication><Scientist><Self Management><Service delivery model><Service model><Services><Statutes and Laws><Stroke><Study Section><System><Teaching><Technology><Telemedicine><Testing><Time><Training><Translating><United Kingdom><United States National Institutes of Health><Update><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Veterans><Virus-HIV><Work><access to health services><access to services><access to treatment><accessibility to health services><availability of services><brain attack><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><care access><care as usual><care coordination><care delivery model><career><cerebral vascular accident><cerebrovascular accident><chronic disorder><circulatory system><co-morbid><co-morbidity><comorbidity><complex chronic conditions><connected care><connected health care><coordinating care><developmental><disparity elimination><disparity in care><disparity in health care><effectiveness trial><eliminate disparities><eliminating disparities><enroll><health and care delivery><health care delivery><health care delivery model><health care disparity><health care inequality><health care inequity><health care quality><health delivery systems><health service access><health services availability><health services delivery><heavy metal Pb><heavy metal lead><high blood pressure><homes><hsr><human immunodeficiency virus research><hyperpiesia><hyperpiesis><hypertension control><hypertension management><hypertensive disease><hypertensive disorder><implementation science><improved><indexing><interest><intervention research><interventional research><interventional study><interventions research><lesson plans><medication therapy management><member><nursing intervention><operation><operations><patient response><patient specific response><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><population health><post intervention><post-doc><post-doctoral><post-doctoral trainee><pragmatic effectiveness trial><pragmatic trial><programs><qualitative reasoning><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><research addressing HIV><research associates><research in HIV><research into HIV><research into practice><research on HIV><research on human immunodeficiency virus><research study><research to address HIV><research to practice><response><response to therapy><response to treatment><responsive patient><risk-reducing><rural health care><rural locality><rural place><rural setting><science on HIV><science to address HIV><self-management program><service availability><services research><social role><stroked><strokes><studies on HIV><telephone based><therapeutic response><therapy response><treatment access><treatment as usual><treatment effect><treatment response><treatment responsiveness><uptake><usual care><virtual assessment><virtual care><virtual evaluation><virtual health care><virtual model><work group><working group>
View Full Project Details on NIH Reporter
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Laura Michelle Heath

SAGE BIONETWORKS, SEATTLE, WA

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$435,881
FY 2025

Project Title

Tox-AD: a new multi-institute tri-consortium data resource in the AD Knowledge Portal

Grant Number:

3U24AG061340-07S2

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2025

End Date:

4/30/2027

Project Abstract

Abstract This supplement will expand the AD Knowledge Portal (adknowledgeportal.org) by incorporating data being generated by a high-value set of projects that are using complementary approaches to characterize how multiple environmental toxicants, such as heavy metals, air pollution, infection, pes...

Research Terms

<AD dementia><AD related dementia><ADRD><Acceleration><Adherence><Administrative Supplement><Affect><Agreement><Air Pollution><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Biologic Models><Biological Markers><Biological Models><Body Tissues><Cell Line><CellLine><Chemical Exposure><Collaborations><Collection><Comment><Commentary><Communities><Complex><Data><Data Coordinating Center><Data Coordination Center><Data Files><Development><Disease><Disorder><Editorial Comment><Ensure><Environmental Exposure><Environmental Toxin><Ethics><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Funding><Genetic><Goals><Grant><Guidelines><Heavy Metals><Human><Individual><Infection><Infrastructure><Investigators><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Legal><Libraries><Metadata><Mice><Mice Mammals><Mission><Model System><Modern Man><Molecular><Multiomic Data><Murine><Mus><NIH><National Institute of Aging><National Institute on Aging><National Institutes of Health><Organoids><Pathway interactions><Pb element><Pesticides><Play><Policies><Primary Senile Degenerative Dementia><Process><Proteomics><Publications><Published Comment><Research><Research Activity><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Risk><Role><Science><Scientific Publication><Scientist><Strains Cell Lines><Symptoms><Systems Biology><Tissues><Toxic Environmental Agents><Toxic Environmental Substances><United States National Institutes of Health><Update><Viewpoint><bio-markers><biologic marker><biomarker><cohort><complex data><cultured cell line><curating data><cytokine><data curation><data dissemination><data diversity><data harmonization><data integration><data interoperability><data management><data modeling><data resource><data sharing><depository><developmental><dietary><diverse data><environmental toxicant><epigenomics><ethical><genomic data><genomic dataset><harmonized data><heavy metal Pb><heavy metal lead><innovate><innovation><innovative><interest><meta data><metabolism measurement><metabolomics><metabonomics><model of data><model the data><modeling of the data><multiple omic data><neuropathologic><neuropathological><neuropathology><novel><open data><open science><open-source data><pathway><prevent><preventing><primary degenerative dementia><programs><repository><response><senile dementia of the Alzheimer type><social role><transcriptomics><work group><working group>
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Susheel Varma

SAGE BIONETWORKS, SEATTLE, WA

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$435,881
FY 2025

Project Title

Tox-AD: a new multi-institute tri-consortium data resource in the AD Knowledge Portal

Grant Number:

3U24AG061340-07S2

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2025

End Date:

4/30/2027

Project Abstract

Abstract This supplement will expand the AD Knowledge Portal (adknowledgeportal.org) by incorporating data being generated by a high-value set of projects that are using complementary approaches to characterize how multiple environmental toxicants, such as heavy metals, air pollution, infection, pes...

Research Terms

<AD dementia><AD related dementia><ADRD><Acceleration><Adherence><Administrative Supplement><Affect><Agreement><Air Pollution><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Biologic Models><Biological Markers><Biological Models><Body Tissues><Cell Line><CellLine><Chemical Exposure><Collaborations><Collection><Comment><Commentary><Communities><Complex><Data><Data Coordinating Center><Data Coordination Center><Data Files><Development><Disease><Disorder><Editorial Comment><Ensure><Environmental Exposure><Environmental Toxin><Ethics><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Funding><Genetic><Goals><Grant><Guidelines><Heavy Metals><Human><Individual><Infection><Infrastructure><Investigators><Knowledge><Knowledge Portal><Knowledge base Portal><Knowledgebase Portal><Lead><Legal><Libraries><Metadata><Mice><Mice Mammals><Mission><Model System><Modern Man><Molecular><Multiomic Data><Murine><Mus><NIH><National Institute of Aging><National Institute on Aging><National Institutes of Health><Organoids><Pathway interactions><Pb element><Pesticides><Play><Policies><Primary Senile Degenerative Dementia><Process><Proteomics><Publications><Published Comment><Research><Research Activity><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Risk><Role><Science><Scientific Publication><Scientist><Strains Cell Lines><Symptoms><Systems Biology><Tissues><Toxic Environmental Agents><Toxic Environmental Substances><United States National Institutes of Health><Update><Viewpoint><bio-markers><biologic marker><biomarker><cohort><complex data><cultured cell line><curating data><cytokine><data curation><data dissemination><data diversity><data harmonization><data integration><data interoperability><data management><data modeling><data resource><data sharing><depository><developmental><dietary><diverse data><environmental toxicant><epigenomics><ethical><genomic data><genomic dataset><harmonized data><heavy metal Pb><heavy metal lead><innovate><innovation><innovative><interest><meta data><metabolism measurement><metabolomics><metabonomics><model of data><model the data><modeling of the data><multiple omic data><neuropathologic><neuropathological><neuropathology><novel><open data><open science><open-source data><pathway><prevent><preventing><primary degenerative dementia><programs><repository><response><senile dementia of the Alzheimer type><social role><transcriptomics><work group><working group>
View Full Project Details on NIH Reporter
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Qi Long

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$415,594
FY 2025

Project Title

Advancing the Coordinating Center for the Canine Cancer Immunotherapy Network

Grant Number:

5U24CA272267-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2022

End Date:

8/31/2027

Project Abstract

The primary mission of the coordinating center (CC) at the University of Pennsylvania is to facilitate the performance of immunotherapy clinical trials in dogs with cancer within the K9CIN (previously known as the Pre- medical Cancer Immunotherapy Network for Canine Trials (PRECINCT)) and to determi...

Research Terms

<Acceleration><Advisory Committees><Area><Bioinformatics><Biological Markers><Biometrics><Biometry><Biostatistics><CCOP><Cancers><Canine Species><Canis familiaris><Clinic><Clinical><Clinical Management><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Design><Clinical Trials Network><Collaborations><Combined Modality Therapy><Communication><Community Clinical Oncology Program><Community Oncology><Consultations><Correlative Study><Data><Data Analyses><Data Analysis><Data Bases><Data Collection><Data Commons><Data Element><Data Management Resources><Data Management System><Data Set><Databases><Deposit><Deposition><Development><Dogs><Dogs Mammals><Enrollment><Ensure><Fostering><Funding><Future><General Population><General Public><Goals><Home><Human><IMiD><Immune Monitoring><Immune mediated therapy><Immune modulatory therapeutic><Immune response><Immunologic Monitoring><Immunological Monitoring><Immunologically Directed Therapy><Immunologist><Immunology procedure><Immunomonitoring><Immunooncology><Immunotherapeutic agent><Immunotherapy><Infrastructure><Investigators><Laboratories><Leadership><Malignant Neoplasms><Malignant Tumor><Medical><Methods><Mission><Modern Man><Monitor><Multimodal Therapy><Multimodal Treatment><Oncology><Oncology Cancer><Patients><Pennsylvania><Performance><Procedures><Process><Production><Productivity><Quality Control><R-Series Research Projects><R01 Mechanism><R01 Program><Reagent><Registries><Reproducibility><Research><Research Design><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Specimen><Research Support><Researchers><Resources><Scientist><Secure><Services><Site><Specimen><Study Type><Task Forces><Technology><Translational Research><Translational Science><Translations><Universities><Work><advisory team><anti-cancer immunotherapy><anticancer immunotherapy><bio-markers><biologic marker><biomarker><biomarker identification><cancer clinical trial><cancer immunotherapy><canine><cloud based><combination therapy><combined modality treatment><combined treatment><comparative><consultation><curating data><data base><data curation><data interpretation><data management><data quality><data sharing><design><designing><developmental><domestic dog><enroll><experience><homes><host response><identification of biomarkers><identification of new biomarkers><immune drugs><immune modulating agents><immune modulating drug><immune modulating therapeutics><immune modulatory agents><immune modulatory drugs><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapeutics><immune-based therapies><immune-based treatments><immune-oncology><immuno oncology><immuno therapy><immunologic assay><immunologic assay/test><immunologic therapeutics><immunology oncology><immunomodulating agents><immunomodulating drugs><immunomodulator agent><immunomodulator drug><immunomodulator medication><immunomodulator prodrug><immunomodulator therapeutic><immunomodulatory agents><immunomodulatory drugs><immunomodulatory therapeutics><immunoresponse><immunotherapeutics><immunotherapy agent><immunotherapy clinical trials><immunotherapy for cancer><immunotherapy of cancer><immunotherapy trials><innovate><innovation><innovative><insight><malignancy><marker identification><meeting><meetings><member><multi-modal therapy><multi-modal treatment><neoplasm/cancer><next generation><novel><oncoimmunology><oncology clinical trial><oncology program><operation><operations><outreach><participant enrollment><patient enrollment><research study><response to therapy><response to treatment><skills><sound><study design><therapeutic response><therapy response><tool><translation><translation research><translational applications><translational investigation><translational study><treatment response><treatment responsiveness><trial design><virtual><web site><website><work group><working group>
View Full Project Details on NIH Reporter
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NICOLA J MASON

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$415,594
FY 2025

Project Title

Advancing the Coordinating Center for the Canine Cancer Immunotherapy Network

Grant Number:

5U24CA272267-04

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2022

End Date:

8/31/2027

Project Abstract

The primary mission of the coordinating center (CC) at the University of Pennsylvania is to facilitate the performance of immunotherapy clinical trials in dogs with cancer within the K9CIN (previously known as the Pre- medical Cancer Immunotherapy Network for Canine Trials (PRECINCT)) and to determi...

Research Terms

<Acceleration><Advisory Committees><Area><Bioinformatics><Biological Markers><Biometrics><Biometry><Biostatistics><CCOP><Cancers><Canine Species><Canis familiaris><Clinic><Clinical><Clinical Management><Clinical Research><Clinical Study><Clinical Trials><Clinical Trials Design><Clinical Trials Network><Collaborations><Combined Modality Therapy><Communication><Community Clinical Oncology Program><Community Oncology><Consultations><Correlative Study><Data><Data Analyses><Data Analysis><Data Bases><Data Collection><Data Commons><Data Element><Data Management Resources><Data Management System><Data Set><Databases><Deposit><Deposition><Development><Dogs><Dogs Mammals><Enrollment><Ensure><Fostering><Funding><Future><General Population><General Public><Goals><Home><Human><IMiD><Immune Monitoring><Immune mediated therapy><Immune modulatory therapeutic><Immune response><Immunologic Monitoring><Immunological Monitoring><Immunologically Directed Therapy><Immunologist><Immunology procedure><Immunomonitoring><Immunooncology><Immunotherapeutic agent><Immunotherapy><Infrastructure><Investigators><Laboratories><Leadership><Malignant Neoplasms><Malignant Tumor><Medical><Methods><Mission><Modern Man><Monitor><Multimodal Therapy><Multimodal Treatment><Oncology><Oncology Cancer><Patients><Pennsylvania><Performance><Procedures><Process><Production><Productivity><Quality Control><R-Series Research Projects><R01 Mechanism><R01 Program><Reagent><Registries><Reproducibility><Research><Research Design><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Specimen><Research Support><Researchers><Resources><Scientist><Secure><Services><Site><Specimen><Study Type><Task Forces><Technology><Translational Research><Translational Science><Translations><Universities><Work><advisory team><anti-cancer immunotherapy><anticancer immunotherapy><bio-markers><biologic marker><biomarker><biomarker identification><cancer clinical trial><cancer immunotherapy><canine><cloud based><combination therapy><combined modality treatment><combined treatment><comparative><consultation><curating data><data base><data curation><data interpretation><data management><data quality><data sharing><design><designing><developmental><domestic dog><enroll><experience><homes><host response><identification of biomarkers><identification of new biomarkers><immune drugs><immune modulating agents><immune modulating drug><immune modulating therapeutics><immune modulatory agents><immune modulatory drugs><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapeutics><immune-based therapies><immune-based treatments><immune-oncology><immuno oncology><immuno therapy><immunologic assay><immunologic assay/test><immunologic therapeutics><immunology oncology><immunomodulating agents><immunomodulating drugs><immunomodulator agent><immunomodulator drug><immunomodulator medication><immunomodulator prodrug><immunomodulator therapeutic><immunomodulatory agents><immunomodulatory drugs><immunomodulatory therapeutics><immunoresponse><immunotherapeutics><immunotherapy agent><immunotherapy clinical trials><immunotherapy for cancer><immunotherapy of cancer><immunotherapy trials><innovate><innovation><innovative><insight><malignancy><marker identification><meeting><meetings><member><multi-modal therapy><multi-modal treatment><neoplasm/cancer><next generation><novel><oncoimmunology><oncology clinical trial><oncology program><operation><operations><outreach><participant enrollment><patient enrollment><research study><response to therapy><response to treatment><skills><sound><study design><therapeutic response><therapy response><tool><translation><translation research><translational applications><translational investigation><translational study><treatment response><treatment responsiveness><trial design><virtual><web site><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Davaalkham - Dambadarjaa

UNIVERSITY OF TEXAS MED BR GALVESTON, GALVESTON, TX

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$292,714
FY 2025

Project Title

2/2 - Mongolian Center for Environmental & Occupational Health - U.S.

Grant Number:

5U2RTW012239-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

PROJECT SUMMARY/ABSTRACT This proposal builds upon more than 15 years of successful US-Mongolia research collaborations in developing an innovative research training program to build sustainable environmental and occupational research capacity in Mongolia. In recent decades, Mongolia has experienced...

Research Terms

<Advisory Committees><Air Pollution><Assay><Bioassay><Biological Assay><Collaborations><Complex><Data Analyses><Data Analysis><Doctor of Philosophy><Economics><Employment><English Language><Environmental Health><Environmental Health Science><Faculty><Fellowship><Financial Support><Fostering><Goals><Health><Health Care Professional><Health Professional><Human><Institution><Interdisciplinary Research><Interdisciplinary Study><International><Investigators><Journals><Laboratories><Magazine><Medial><Modern Man><Mongolia><Multidisciplinary Collaboration><Multidisciplinary Research><National Health Policy><Occupational><Occupational Diseases><Occupational Health><Oral><Ph.D.><PhD><Policies><Position><Positioning Attribute><Process><Publishing><Qualifying><R-Series Research Projects><R01 Mechanism><R01 Program><Reproducibility><Research><Research Ethics><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Specimen><Research Training><Researchers><Science><Specimen><Task Forces><Training><Training Programs><Training Support><Travel><Twin Multiple Birth><Twins><Universities><Viral Respiratory Tract Infection><Work><Writing><advisory team><animal research subject><career><data interpretation><economic><environmental change><experience><faculty mentor><financial assistance><innovate><innovation><innovative><interdisciplinary collaboration><member><occupational disease/disorder><occupational disorder><programs><responsible research conduct><transdisciplinary collaboration><viral respiratory infection>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gregory Charles Gray

UNIVERSITY OF TEXAS MED BR GALVESTON, GALVESTON, TX

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$292,714
FY 2025

Project Title

2/2 - Mongolian Center for Environmental & Occupational Health - U.S.

Grant Number:

5U2RTW012239-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

PROJECT SUMMARY/ABSTRACT This proposal builds upon more than 15 years of successful US-Mongolia research collaborations in developing an innovative research training program to build sustainable environmental and occupational research capacity in Mongolia. In recent decades, Mongolia has experienced...

Research Terms

<Advisory Committees><Air Pollution><Assay><Bioassay><Biological Assay><Collaborations><Complex><Data Analyses><Data Analysis><Doctor of Philosophy><Economics><Employment><English Language><Environmental Health><Environmental Health Science><Faculty><Fellowship><Financial Support><Fostering><Goals><Health><Health Care Professional><Health Professional><Human><Institution><Interdisciplinary Research><Interdisciplinary Study><International><Investigators><Journals><Laboratories><Magazine><Medial><Modern Man><Mongolia><Multidisciplinary Collaboration><Multidisciplinary Research><National Health Policy><Occupational><Occupational Diseases><Occupational Health><Oral><Ph.D.><PhD><Policies><Position><Positioning Attribute><Process><Publishing><Qualifying><R-Series Research Projects><R01 Mechanism><R01 Program><Reproducibility><Research><Research Ethics><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Specimen><Research Training><Researchers><Science><Specimen><Task Forces><Training><Training Programs><Training Support><Travel><Twin Multiple Birth><Twins><Universities><Viral Respiratory Tract Infection><Work><Writing><advisory team><animal research subject><career><data interpretation><economic><environmental change><experience><faculty mentor><financial assistance><innovate><innovation><innovative><interdisciplinary collaboration><member><occupational disease/disorder><occupational disorder><programs><responsible research conduct><transdisciplinary collaboration><viral respiratory infection>
View Full Project Details on NIH Reporter
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Habibul Ahsan

UNIVERSITY OF CHICAGO, CHICAGO, IL

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$292,583
FY 2025

Project Title

2/2 Bangladesh Center for Global Environmental and Occupational Health-US

Grant Number:

5U2RTW010122-09

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/28/2015

End Date:

2/28/2027

Project Abstract

ABSTRACT: This is the renewal U2R application for the “Bangladesh Center for Global Environmental and Occupational Health (GEOHealth)”- awarded along with the linked U01 grant in 2015 to the University of Chicago (UofC) and International Centre for Diarrheal Disease Research, Bangladesh (ICDDR,B). T...

Research Terms

<AI system><Acute><Address><Artificial Intelligence><Award><Bangladesh><Chicago><Collaborations><Computer Reasoning><Country><Curriculum><Custom><Data Science><Degree program><Educational Curriculum><Educational workshop><Ensure><Environmental Health><Environmental Health Science><Evaluation><Fellowship><Foundations><Funding><Goals><Grant><Image Analyses><Image Analysis><Influentials><Institution><Investigators><Knowledge><Link><Machine Intelligence><Machine Learning><Master of Science><Master's Degree><Medical><Mentors><Modernization><Monitor><Occupational Health><Participant><Peer Review><Phase><Postdoc><Postdoctoral Fellow><Productivity><Publications><Reporting><Research><Research Associate><Research Methodology><Research Methods><Research Personnel><Researchers><Scientific Publication><Students><System><Techniques><Technology><Training><Training Activity><Training Programs><Universities><Work><Workshop><analytical tool><career><career development><customs><design><designing><diarrheal disease><diarrheal illness><global environment><global environmental><health data><image evaluation><image interpretation><international center><lesson plans><m-Health><mHealth><machine based learning><mobile health><post-doc><post-doctoral><post-doctoral trainee><post-doctoral training><programs><research and methods><research associates><satisfaction><success><tool><training module>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RUBHANA RAQIB

UNIVERSITY OF CHICAGO, CHICAGO, IL

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$292,583
FY 2025

Project Title

2/2 Bangladesh Center for Global Environmental and Occupational Health-US

Grant Number:

5U2RTW010122-09

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/28/2015

End Date:

2/28/2027

Project Abstract

ABSTRACT: This is the renewal U2R application for the “Bangladesh Center for Global Environmental and Occupational Health (GEOHealth)”- awarded along with the linked U01 grant in 2015 to the University of Chicago (UofC) and International Centre for Diarrheal Disease Research, Bangladesh (ICDDR,B). T...

Research Terms

<AI system><Acute><Address><Artificial Intelligence><Award><Bangladesh><Chicago><Collaborations><Computer Reasoning><Country><Curriculum><Custom><Data Science><Degree program><Educational Curriculum><Educational workshop><Ensure><Environmental Health><Environmental Health Science><Evaluation><Fellowship><Foundations><Funding><Goals><Grant><Image Analyses><Image Analysis><Influentials><Institution><Investigators><Knowledge><Link><Machine Intelligence><Machine Learning><Master of Science><Master's Degree><Medical><Mentors><Modernization><Monitor><Occupational Health><Participant><Peer Review><Phase><Postdoc><Postdoctoral Fellow><Productivity><Publications><Reporting><Research><Research Associate><Research Methodology><Research Methods><Research Personnel><Researchers><Scientific Publication><Students><System><Techniques><Technology><Training><Training Activity><Training Programs><Universities><Work><Workshop><analytical tool><career><career development><customs><design><designing><diarrheal disease><diarrheal illness><global environment><global environmental><health data><image evaluation><image interpretation><international center><lesson plans><m-Health><mHealth><machine based learning><mobile health><post-doc><post-doctoral><post-doctoral trainee><post-doctoral training><programs><research and methods><research associates><satisfaction><success><tool><training module>
View Full Project Details on NIH Reporter
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WAEL K AL-DELAIMY

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$291,630
FY 2025

Project Title

2/2 GeoHealth Hub for Climate Change and Health in the Middle East and North Africa-U.S.

Grant Number:

5U2RTW012228-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

Abstract Climate change is a well-documented reality that is impacting planet earth and its inhabitants. The health impacts of climate change have been studied in terms of heat wave, air pollution, spread of vectors of infectious diseases, and extreme weather events of flooding, drought, wildfires, ...

Research Terms

<Address><Air Pollution><Area><Awareness><California><Climate><Collaborations><Communicable Diseases><Communities><Cost Effectiveness Analysis><Doctor of Philosophy><Droughts><Dust><Earth><Economic Models><Educational workshop><Environmental Health><Environmental Health Science><Event><Flooding><Floods><Grant><Health><Health Benefit><Health Policy><Health Sciences><Heat Waves><Human><Individual><Infectious Diseases><Infectious Disorder><Institution><Intervention><Jordan><Lebanon><Link><Local Government><Mental disorders><Mental health disorders><Mentors><Meteorological Climate><Middle East><Modern Man><Morocco><North Africa><Northern Africa><Ph.D.><PhD><Planet Earth><Policies><Policy Maker><Pollution><Precipitation><Psychiatric Disease><Psychiatric Disorder><Research><Research Training><Risk><Science><Technology><Training><Training Programs><Universities><Visit><Wildfire><Work><Workshop><climate and health><climate change><climate health><climate impact><climate-related health><climatic><climatic changes><conference><convention><cost efficient analysis><cost-effective analysis><dissemination science><extreme weather><global climate change><health care policy><heatwave><implementation science><institutional capacity><mental illness><precipitations><programs><psychiatric illness><psychological disorder><summit><symposia><symposium><vector><virtual><water quality><webinar><wild fire><wildland fire>
View Full Project Details on NIH Reporter
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Fayez Ahmad Abdulla

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$291,630
FY 2025

Project Title

2/2 GeoHealth Hub for Climate Change and Health in the Middle East and North Africa-U.S.

Grant Number:

5U2RTW012228-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

Abstract Climate change is a well-documented reality that is impacting planet earth and its inhabitants. The health impacts of climate change have been studied in terms of heat wave, air pollution, spread of vectors of infectious diseases, and extreme weather events of flooding, drought, wildfires, ...

Research Terms

<Address><Air Pollution><Area><Awareness><California><Climate><Collaborations><Communicable Diseases><Communities><Cost Effectiveness Analysis><Doctor of Philosophy><Droughts><Dust><Earth><Economic Models><Educational workshop><Environmental Health><Environmental Health Science><Event><Flooding><Floods><Grant><Health><Health Benefit><Health Policy><Health Sciences><Heat Waves><Human><Individual><Infectious Diseases><Infectious Disorder><Institution><Intervention><Jordan><Lebanon><Link><Local Government><Mental disorders><Mental health disorders><Mentors><Meteorological Climate><Middle East><Modern Man><Morocco><North Africa><Northern Africa><Ph.D.><PhD><Planet Earth><Policies><Policy Maker><Pollution><Precipitation><Psychiatric Disease><Psychiatric Disorder><Research><Research Training><Risk><Science><Technology><Training><Training Programs><Universities><Visit><Wildfire><Work><Workshop><climate and health><climate change><climate health><climate impact><climate-related health><climatic><climatic changes><conference><convention><cost efficient analysis><cost-effective analysis><dissemination science><extreme weather><global climate change><health care policy><heatwave><implementation science><institutional capacity><mental illness><precipitations><programs><psychiatric illness><psychological disorder><summit><symposia><symposium><vector><virtual><water quality><webinar><wild fire><wildland fire>
View Full Project Details on NIH Reporter
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Rima Habib

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/2 Global Environmental and Occupational Health Hub for Research Training in the Middle East and North Africa Region (GEOHealth MENA)

Grant Number:

5U2RTW012231-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<Agricultural Workers><Agriculture><American><Collaborations><Communities><Country><Disparity population><Doctor of Philosophy><Egypt><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Fellowship><Health><Health Sciences><Industrial Medicine><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lebanon><Medicine><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Outcome><Pathway interactions><Performance><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Practice Guidelines><Qualifying><Refugees><Regulation><Research><Research Training><Role><Safety><Scholarship><Sister><Sudan><Syrian><Training><Translating><Universities><agriculture worker><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><epidemiologic><epidemiological><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><involuntary migration><low and middle-income countries><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><social factors><social role><subgroup disparity><unequal group><unequal population>
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Hani Mowafi

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/2 Global Environmental and Occupational Health Hub for Research Training in the Middle East and North Africa Region (GEOHealth MENA)

Grant Number:

5U2RTW012231-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<Agricultural Workers><Agriculture><American><Collaborations><Communities><Country><Disparity population><Doctor of Philosophy><Egypt><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Fellowship><Health><Health Sciences><Industrial Medicine><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lebanon><Medicine><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Outcome><Pathway interactions><Performance><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Practice Guidelines><Qualifying><Refugees><Regulation><Research><Research Training><Role><Safety><Scholarship><Sister><Sudan><Syrian><Training><Translating><Universities><agriculture worker><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><epidemiologic><epidemiological><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><involuntary migration><low and middle-income countries><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><social factors><social role><subgroup disparity><unequal group><unequal population>
View Full Project Details on NIH Reporter
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IMAN A NUWAYHID

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/2 Global Environmental and Occupational Health Hub for Research Training in the Middle East and North Africa Region (GEOHealth MENA)

Grant Number:

5U2RTW012231-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<Agricultural Workers><Agriculture><American><Collaborations><Communities><Country><Disparity population><Doctor of Philosophy><Egypt><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Fellowship><Health><Health Sciences><Industrial Medicine><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lebanon><Medicine><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Outcome><Pathway interactions><Performance><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Practice Guidelines><Qualifying><Refugees><Regulation><Research><Research Training><Role><Safety><Scholarship><Sister><Sudan><Syrian><Training><Translating><Universities><agriculture worker><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><epidemiologic><epidemiological><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><involuntary migration><low and middle-income countries><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><social factors><social role><subgroup disparity><unequal group><unequal population>
View Full Project Details on NIH Reporter
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CARRIE A REDLICH

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/2 Global Environmental and Occupational Health Hub for Research Training in the Middle East and North Africa Region (GEOHealth MENA)

Grant Number:

5U2RTW012231-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<Agricultural Workers><Agriculture><American><Collaborations><Communities><Country><Disparity population><Doctor of Philosophy><Egypt><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Fellowship><Health><Health Sciences><Industrial Medicine><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lebanon><Medicine><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Outcome><Pathway interactions><Performance><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Practice Guidelines><Qualifying><Refugees><Regulation><Research><Research Training><Role><Safety><Scholarship><Sister><Sudan><Syrian><Training><Translating><Universities><agriculture worker><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><epidemiologic><epidemiological><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><involuntary migration><low and middle-income countries><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><social factors><social role><subgroup disparity><unequal group><unequal population>
View Full Project Details on NIH Reporter
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Diane S Rohlman

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/2 Global Environmental and Occupational Health Hub for Research Training in the Middle East and North Africa Region (GEOHealth MENA)

Grant Number:

5U2RTW012231-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<Agricultural Workers><Agriculture><American><Collaborations><Communities><Country><Disparity population><Doctor of Philosophy><Egypt><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Fellowship><Health><Health Sciences><Industrial Medicine><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lebanon><Medicine><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Outcome><Pathway interactions><Performance><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Practice Guidelines><Qualifying><Refugees><Regulation><Research><Research Training><Role><Safety><Scholarship><Sister><Sudan><Syrian><Training><Translating><Universities><agriculture worker><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><epidemiologic><epidemiological><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><involuntary migration><low and middle-income countries><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><social factors><social role><subgroup disparity><unequal group><unequal population>
View Full Project Details on NIH Reporter
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Carine Sakr

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$289,052
FY 2025

Project Title

2/2 Global Environmental and Occupational Health Hub for Research Training in the Middle East and North Africa Region (GEOHealth MENA)

Grant Number:

5U2RTW012231-04

Activity Code:

U2R

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Project Abstract

7. Project Summary/Abstract The Middle East and North Africa (MENA) region, especially its LMIC countries, faces a myriad of environmental and occupational health (EOH) challenges in a context of dynamic political changes, multiple concurrent humanitarian crises, weak regulations, and limited invest...

Research Terms

<Agricultural Workers><Agriculture><American><Collaborations><Communities><Country><Disparity population><Doctor of Philosophy><Egypt><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Face><Faculty><Fellowship><Health><Health Sciences><Industrial Medicine><Institution><Interdisciplinary Research><Interdisciplinary Study><Investments><Iowa><LMIC><Lebanon><Medicine><Middle East><Migrant><Multidisciplinary Collaboration><Multidisciplinary Research><North Africa><Northern Africa><Occupational Health><Occupational Medicine><Occupational or Industrial Medicine><Outcome><Pathway interactions><Performance><Pesticides><Ph.D.><PhD><Policies><Politics><Population><Practice Guidelines><Qualifying><Refugees><Regulation><Research><Research Training><Role><Safety><Scholarship><Sister><Sudan><Syrian><Training><Translating><Universities><agriculture worker><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><displaced people><displaced person><epidemiologic><epidemiological><faces><facial><forced migrant><global environment><global environmental><group disparity><group inequality><group inequity><health training><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><involuntary migration><low and middle-income countries><neurobehavioral><pathway><pesticide exposure><population inequality><population inequity><social factors><social role><subgroup disparity><unequal group><unequal population>
View Full Project Details on NIH Reporter
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Andrew Curnow

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 28/100
Training-friendly
Active award
$89,860
FY 2025

Project Title

The effect of body composition on patient-centered outcomes in advanced interstitial lung disease

Grant Number:

1F32HL182143-01

Activity Code:

F32

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

9/1/2025

End Date:

8/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary/Abstract Interstitial lung diseases (ILD) are a group of chronic lung diseases characterized by progressive fibrosis and loss of lung function over time. Prior research has appropriately focused on respiratory function and attenuation of disease progression; however, the myriad impa...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Accuracy of Diagnosis><Adult><Adult Human><Affect><Age><Age Years><Aged 65 and Over><Aging><Airway failure><American><BMI><BMI percentile><BMI z-score><Bioelectrical Impedance><Biolectric Impedance><Biometrics><Biometry><Biostatistics><Body Composition><Body Measures><Body fat><Body mass index><Body measure procedure><COPD><Categories><Cessation of life><Chest><Chronic Obstruction Pulmonary Disease><Chronic Obstructive Lung Disease><Chronic Obstructive Pulmonary Disease><Chronic lung disease><Classification><Clinical><Cross Sectional Analysis><Cross-Sectional Analyses><Cross-Sectional Studies><Cross-Sectional Survey><Data><Death><Dedications><Development and Research><Discipline><Disease><Disease Frequency Surveys><Disease Progression><Disorder><Epidemiology><Evaluation><Exclusion Criteria><Fats><Fatty acid glycerol esters><Fibrosing Alveolitis><Fibrosis><Fibrotic lesions in lung><Generalized Growth><Geriatrics><Goals><Growth><Health><Interstitial Lung Diseases><Investigators><Life Sanctities><Long-term cohort study><Longitudinal cohort study><Lung><Lung Grafting><Lung Respiratory System><Lung Transplantation><Lung scar><Lung tissue scar><Measures><Mentorship><Morbidity><Morbidity - disease rate><Muscle Atrophy><Muscle function><Muscular Atrophy><Non obese><Nonobese><Obesity><Outcome><Outcome Measure><Participant><Pathologic><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Persons><Phenotype><Physical Performance><Population><Prevalence><Progressive Disease><Prospective, cohort study><Psychometrics><Pulmonary Body System><Pulmonary Graft><Pulmonary Organ System><Pulmonary Scar><Pulmonary Tissue fibrosis><Pulmonary Transplant><Pulmonary Transplantation><QOL><Quality of life><Questionnaires><Quetelet index><R & D><R&D><Research><Research Personnel><Researchers><Respect for Life><Respiratory Failure><Respiratory System><Respiratory Tracts><Respiratory physiology><Respiratory tract structure><Risk><Risk Factors><Running><Sanctity of Life><Scarring at the lung><Scarring in the lung><Societies><Systematics><Thorace><Thoracic><Thorax><Time><Tissue Growth><Training><Transplantation><Value of Life><Visit><Walking><above age 65><adiposity><adulthood><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age associated alterations><age associated changes><age correlated alterations><age correlated changes><age dependent alterations><age dependent changes><age induced alterations><age induced changes><age of 65 years onward><age related alterations><age related changes><age specific alterations><age specific changes><aged 65 and greater><aged 65+><aged ≥65><ages><aging associated alterations><aging associated changes><aging associated disease><aging associated disorders><aging correlated alterations><aging correlated changes><aging dependent alterations><aging dependent changes><aging induced alterations><aging induced changes><aging related alterations><aging related changes><aging related disease><aging related disorders><aging specific alterations><aging specific changes><alterations with age><attenuation><career><career development><changes with age><chronic obstructive pulmonary disorder><chronic pulmonary disease><cohort><corpulence><decreased muscle mass><diagnostic accuracy><diffuse interstitial pulmonary fibrosis><disability><disease associated with aging><disease of aging><disorder of aging><disorders associated with aging><disorders related to aging><epidemiologic><epidemiological><exercise capacity><experience><fibrosing interstitial lung disease><fibrotic interstitial lung disease><fibrotic lung><frailty><functional status><geriatric medicine><health related quality of life><human old age (65+)><idiopathic pulmonary fibrosis><inclusion criteria><insight><interest><low muscle mass><lung function><lung transplant><malleable risk><measurable outcome><modifiable risk><mortality><muscle breakdown><muscle bulk><muscle degradation><muscle deterioration><muscle form><muscle loss><muscle mass><muscle wasting><natural aging><normal aging><normative aging><novel><older adult><older adulthood><ontogeny><outcome measurement><over 65 years><patient centered><patient oriented><patient oriented outcomes><physical conditioning><physical disability><physical health><physically disabled><physically handicapped><pulmonary><pulmonary function><reduced muscle mass><research and development><respiratory><respiratory function><sarcopenia><sarcopenic><sarcopenic obesity><transplant><≥65 years>
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Alea Christine Delmastro

STANFORD UNIVERSITY, STANFORD, CA

Exploratory lead · 28/100
Training-friendly
Active award
$42,574
FY 2025

Project Title

Gravidity-dependent Mechanisms of Myeloid Cell-mediated Protection against Placental Malaria

Grant Number:

1F31AI191425-01

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

9/1/2025

End Date:

8/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Malaria in pregnancy is one of the leading causes of infant death globally. Placental malaria (PM) is the main mechanism by which malaria in pregnancy causes birth complications, such as preterm birth, stillbirth, and low birth weight. During PM, Plasmodium falciparum (Pf)-i...

Research Terms

<0-11 years old><2nd trimester><7S Gamma Globulin><Affect><Africa South of the Sahara><Allogenic><Antibodies><Assay><Automobile Driving><Bioassay><Biological Assay><Birth><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood erythrocyte><Blood monocyte><Body Tissues><Cell Body><Cell Communication><Cell Interaction><Cell-Mediated Cytolysis><Cell-Mediated Lympholysis><Cell-to-Cell Interaction><Cells><Cells Placenta-Tissue><Cellular Cytotoxicity><Child><Child Youth><Children (0-21)><Chondroitin 4 Sulfate><Chondroitin Sulfate A><Clinical><Clinical Trials><Cytotoxic cell><Data><Enrollment><Equilibrium><Erythrocytes><Erythrocytic><Fetus><Gestation><Gravid><Gravidity><IgG><IgG Receptors><Immune><Immune Tolerance><Immune system><Immunes><Immunity><Immunoglobulin G><Immunoglobulin G Receptor><Immunologic Tolerance><Immunology><In Situ><Infant Mortality><Infant Mortality Total><Infection><Infiltration><Inflammation><Inflammatory><K lymphocyte><Lead><Link><Low Birth Weight Infant><Lymphocyte Cytotoxicity><Lymphocytotoxicity><Macrophage><Malaria><Marrow erythrocyte><Marrow monocyte><Maternal Mortality><Maternal-Fetal Exchange><Maternal-fetal medicine><Mediating><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Methods><Midtrimester><Modification><Myelogenous><Myeloid><Myeloid Cells><Mφ><NK Cells><Natural Killer Cells><Neonatal><Normal Placentoma><Outcome><P falciparum><P. falciparum><P.falciparum><Paludism><Parasitemia><Parturition><Pathogenesis><Pathologic><Patients><Pb element><Perinatal Mortalities><Perinatal lethality><Perinatal mortality demographics><Phagocytes><Phagocytic Cell><Phagocytosis><Phenotype><Placenta><Placenta Embryonic Tissue><Placentome><Plasma><Plasma Serum><Plasmodium Infections><Plasmodium falciparum><Pregnancy><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Production><Proteomics><Receptor Protein><Red Blood Cells><Red Cell><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Second Pregnancy Trimester><Second Trimester><Severities><Severity of illness><Shapes><Sub-Saharan Africa><Subsaharan Africa><Surface Proteins><Syncytiotrophoblast><Testing><Therapeutic><Tissue Procurements><Tissues><Transplacental Exposure><Uganda><Variant><Variation><Whole Blood><Woman><Work><acquired immunity><adverse birth outcomes><amebocyte><balance><balance function><biobank><biorepository><birth complications><blood corpuscles><cell mediated cytotoxicity><cell mediated immune response><death among infants><death in first year of life><death in infancy><death in infants><delivery complications><develop a vaccine><develop vaccines><development of a vaccine><disease severity><driving><enroll><expectant mother><expectant women><expectation><expecting mother><expecting women><gamma Fc Receptors><healthy pregnancy><heavy metal Pb><heavy metal lead><imaging approach><imaging based approach><immune system tolerance><immune unresponsiveness><immunological paralysis><improved><improved outcome><in vitro Model><individuals who are pregnant><infant death><infant demise><infantile death><insight><kids><low birth weight><low birthweight><maternal death><maternal morbidity><maternal-fetal interface><monocyte><mortality in infants><nanostring><neonatal outcome><novel><parasaetemia><people who are pregnant><perinatal deaths><perinatal morbidity><placenta infection><placental infection><placental malaria><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><preterm delivery><prevent><preventing><receptor><receptor binding><receptor bound><receptor expression><recruit><response><social role><spatial relationship><stillbirth><stillborn><those who are pregnant><transcriptomics><vaccine development><women who are pregnant><youngster>
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Christopher Kanakry

DIVISION OF BASIC SCIENCES - NCI

Exploratory lead · 24/100
Large award
$3,453,330
FY 2025

Project Title

Deciphering the efficacy of posttransplant cyclophosphamide in BMT

Grant Number:

1ZIABC011659-11

Activity Code:

ZIA

Mechanism:

Intramural Research

Agency:

NIH

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

In our work over the past several years, we have overturned the prior paradigm regarding how post-transplantation cyclophosphamide (PTCy) prevents graft-versus-host disease (GVHD) and have worked to develop a new mechanistic framework. Across several active projects, we are continuing to refine and ...

Research Terms

<Allo BMT><Allogeneic BMT><Allogeneic Bone Marrow Transplantation><B Cells Mixed T Cells><Back><Bone Marrow Grafting><Bone Marrow Transplant><Bone Marrow Transplantation><CAR T cells><CAR modified T cells><CAR-T><CAR-Ts><CTX><CYCLO-cell><Carloxan><Cell Therapy><Ciclofosfamida><Ciclofosfamide><Cicloxal><Clafen><Claphene><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Cycloblastin><Cycloblastine><Cyclophospham><Cyclophosphamide><Cyclophosphamidum><Cyclophosphan><Cyclophosphane><Cyclophosphanum><Cyclostin><Cyclostine><Cytophosphan><Cytophosphane><Cytoxan><Data><Donor Lymphocyte Infusion><Dorsum><Dose><Drug Kinetics><Endoxan><Endoxana><Enduxan><Engraftment><Enrollment><Ensure><Fosfaseron><Genoxal><Genuxal><Goals><GvHD><HL-A Antigens><HLA Antigens><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematology><Hematopoietic><Hematopoietic Cancer><Histocompatibility Complex><Histocompatibility Complices><Homologous Wasting Disease><Human><Human Leukocyte Antigens><Immune><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Institution><Laboratories><Laboratory Research><Ledoxina><Leukocyte Antigens><MLC test><MLR test><Major Histocompatibility Complex><Major Histocompatibility Complices><Malignant Hematologic Neoplasm><Marrow Transplantation><Mitoxan><Mixed Leukocyte Culture Test><Mixed Leukocyte Reaction><Mixed Lymphocyte Culture><Mixed Lymphocyte Culture Test><Mixed Lymphocyte Reaction><Modeling><Modern Man><Modification><Neosar><Non-Malignant><Outcome><PBPC transplantation><PBSC transplantation><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Peripheral Blood Progenitor Cell Transplantation><Peripheral Blood Stem Cell (PBSC) Transplantation><Peripheral Blood Stem Cell Transplantation><Peripheral Stem Cell Transplantation><Pharmacokinetics><Phase><Preparation><Procytox><Publications><Publishing><Recovery><Relapse><Risk Reduction><Runt Disease><Scientific Publication><Sendoxan><Siblings><Syklofosfamid><T cells for CAR><T-Cells><T-Lymphocyte><Toxic effect><Toxicities><Translating><Translations><Transplant-Related Disorder><Transplantation><Transplantation Conditioning><Work><Zytoxan><allogeneic bone marrow transplant><allogenic bone marrow transplant><arm><bone marrow allograft><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular therapeutic><cellular therapy><chimeric antigen T cell receptor><chimeric antigen receptor (CAR) T cells><chimeric antigen receptor T><chimeric antigen receptor T cells><chimeric antigen receptor fusion protein T-cells><chimeric antigen receptor modified T cells><clinical efficacy><clinical translation><clinical trial enrollment><clinically translatable><conditioning><disease control><disorder control><enroll><graft versus host disease><graft vs host disease><graft vs. host disease><hemopoietic><improved><improved outcome><mixed lymphocyte reaction test><mouse model><murine model><new approaches><nonmalignant><novel approaches><novel strategies><novel strategy><patient oriented outcomes><peripheral blood stem cell support><peripheral stem cell support><post-transplant><post-transplantation><posttransplant><posttransplantation><pre-clinical><preclinical><preparations><prevent><preventing><prophylactic><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><standard of care><stem><thymus derived lymphocyte><translation><transplant><transplant disease>
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Birgit Schilling

BUCK INSTITUTE FOR RESEARCH ON AGING, NOVATO, CA

Exploratory lead · 24/100
Large award
$1,759,412
FY 2025

Project Title

timsTOF fleX MALDI-2 for Spatial Molecular Imaging

Grant Number:

1S10OD038264-01

Activity Code:

S10

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2025

End Date:

3/31/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT This shared instrumentation proposal seeks funding for the purchase of a Bruker ‘timsTOF fleX MALDI-2 for Spatial Molecular Imaging’ including a bundled HTX M3+ sprayer. This new mass spectrometry (MS) platform will facilitate ongoing and future scientific research to spatia...

Research Terms

<AD dementia><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Architecture><Biology of Aging><Body Tissues><Code><Coding System><Data Bases><Databases><Decline in mobility><Decrease in mobility><Decreased mobility><Degenerative Arthritis><Degenerative polyarthritis><Diminished mobility><Engineering / Architecture><Funding><Future><Glycans><Grant><Health><Human><Huntington Chorea><Huntington Disease><Huntington's><Huntington's Disease><Huntingtons Disease><Imaging technology><Institution><Investigators><Kidney Diseases><Laser Electromagnetic><Laser Radiation><Lasers><Libraries><Lipids><MALD-MS><MALDI><MALDI-MS><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measurement><Metabolic Diseases><Metabolic Disorder><Mobility decline><Mobility impairment><Modern Man><Molecular Fingerprinting><Molecular Profiling><Monitor><NIH><National Institutes of Health><Nephropathy><Noise><Organ><Organoids><Osteoarthritis><Osteoarthrosis><Parkinsonian><Parkinsonian Condition><Parkinsonian Diseases><Parkinsonian Disorders><Parkinsonian Syndrome><Parkinsonism><Polysaccharides><Preparation><Primary Senile Degenerative Dementia><Principal Investigator><Proteins><Proteomics><Reduced mobility><Reduction in mobility><Renal Disease><Research><Research Institute><Research Personnel><Researchers><Resolution><Sampling><Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization><Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization><System><Thesaurismosis><Tissues><United States National Institutes of Health><Universities><age associated disease><age associated disorder><age associated impairment><age dependent disease><age dependent disorder><age dependent impairment><age related human disease><age-related disease><age-related disorder><age-related impairment><animal tissue><cost><data base><degenerative joint disease><equipment acquirement><equipment acquisition><equipment investment><equipment procurement><equipment purchase><equipment purchasing><healthspan><healthy life span><human tissue><hypertrophic arthritis><imaging mass spectrometry><improved><innovate><innovation><innovative><instrument acquisition><instrument investment><instrument procurement><instrument purchase><instrumentation><ion mobility><ionization><kidney disorder><lipidomics><mass spectrometric imaging><matrix assisted laser desorption ionization><metabolism disorder><metabolism measurement><metabolomics><metabonomics><meter><molecular imaging><molecular mass><molecular profile><molecular signature><molecule imaging><multiomics><multiple omics><novel><panomics><preparations><primary degenerative dementia><renal disorder><resolutions><senile dementia of the Alzheimer type><spatial molecular analysis><spatial molecular imaging><spatial molecular mapping><spatial molecular profiling>
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TERENCE S. DERMODY

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 24/100
Active award
Career award
$237,419
FY 2026

Project Title

Molecular Basis of Pediatric Disease

Grant Number:

5K12HD052892-19

Activity Code:

K12

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/10/2007

End Date:

11/30/2027

Project Abstract

This proposal requests continued Child Health Research Career Development Award (CHRCDA) support for the Molecular Basis of Pediatric Disease Training Program at the University of Pittsburgh and UPMC Children’s Hospital of Pittsburgh (CHP). The primary goal of the Molecular Basis of Pediatric Diseas...

Research Terms

<Award><Biomedical Research><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Child Health><Childhood><Children's Hospital><Dedications><Department chair><Disease><Disorder><Environment><Faculty><Fostering><Funding><Future><Goals><Grant><Individual><Investigators><K-Awards><K-Series Research Career Programs><Laboratories><Mentors><Molecular><NIH><National Institutes of Health><Outcome><Pediatric Hospitals><Pediatric Research><Physicians><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Reproducibility><Request for Proposals><Research><Research Career Program><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Scholars Program><Scientific Inquiry><Scientific Publication><Scientist><Secure><Talents><Training><Training Programs><United States National Institutes of Health><Universities><Writing><career><design><designing><experience><faculty mentor><full professor><high standard><improved><innovate><innovation><innovative><pediatric><pediatric department><peer coaching><peer instruction><peer led team learning><peer mentoring><peer teaching><programs><senior faculty><sq. ft><square foot><training opportunity>
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Bryan R Greenhouse

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 24/100
Active award
Career award
$197,626
FY 2026

Project Title

Mentoring translational scientists in international infectious disease research

Grant Number:

5K24AI144048-08

Activity Code:

K24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/22/2019

End Date:

12/31/2028

Project Abstract

Abstract Dr. Greenhouse is a physician scientist trained in internal medicine, infectious diseases, and biostatistics. Over the past 18 years, he has worked across domains of field epidemiology, laboratory science, data science, and public health to investigate the epidemiology of infectious diseas...

Research Terms

<Acceleration><Address><African><Algorithms><Anti-malarials><Area><Assay><Award><Bioassay><Bioinformatics><Biological Assay><Biometrics><Biometry><Biostatistics><Birth><Blood><Blood Plasma><Blood Reticuloendothelial System><COBRE><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Career Choice><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Career Path><Case Management><Center of Biomedical Research Excellence><Centers of Research Excellence><Circulation><Cities><Classification><Clinical><Collaborations><Communicable Diseases><Communication><Communities><Community Health><Computer Analysis><Computerized Medical Record><Country><Data><Data Analyses><Data Analysis><Data Science><Dedications><Development><Economic Income><Economical Income><Educational process of instructing><Educational workshop><Electronic Medical Record><Enrollment><Epidemiologic Research><Epidemiologic analysis><Epidemiology><Fever><Functional Metagenomics><Funding><Future><Generalized Growth><Generations><Geography><Goals><Grant><Growth><Guidelines><Health><Health Care Facility><Health Facilities><Household><Immigrant><Immigrant community><Immunity><Immunology><Income><Infectious Disease Epidemiology><Infectious Diseases><Infectious Diseases / Laboratory><Infectious Diseases Research><Infectious Disorder><Infectious Epidemiology><Infrastructure><Internal Medicine><International><Intervention><Investigators><K-Awards><K-Series Research Career Programs><K24 Award><K24 Mechanism><K24 Program><Laboratories><Learning><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Malaria><Mentors><Mentorship><Metagenomics><Methods><Mid-Career Clinical Scientist Award (K24)><Midcareer Investigator Award in Patient-Oriented Research><Midcareer Investigator Award in Patient-Oriented Research (K24)><NGS Method><NGS system><NIAID><NIH><National Institute of Allergy and Infectious Disease><National Institutes of Health><Paludism><Paper><Parturition><Peer Review><Physicians><Pilot Projects><Plasma><Plasma Serum><Plasmodium Infections><Population><Principal Investigator><Public Health><Publishing><Pyrexia><Research><Research Career Program><Research Personnel><Research Specimen><Researchers><Residual><Residual state><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Respiratory infectious agent><Respiratory tract pathogen><Reticuloendothelial System, Serum, Plasma><Risk Factors><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Sampling><San Francisco><Science><Scientist><Sentinel><Sentinel Surveillance><Sentinel Surveillances><Serology><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Site><Specimen><System><Systematics><Teaching><Technology><Testing><Time><Tissue Growth><Training><Training Programs><Translational Research><Translational Science><Transmission><Treatment Efficacy><Uganda><United States National Institutes of Health><Work><Workshop><acquired immunity><analytical method><anti-malarial agents><anti-malarial drugs><burden of disease><burden of illness><burden of infection><care facilities><career><career aspiration><career development><career interest><career pathway><career track><cohort><communicable disease transmission><community-based health><computational analyses><computational analysis><computer analyses><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><data interpretation><developmental><disease burden><disease transmission><efficacy study><enroll><epidemiologic><epidemiologic evaluation><epidemiologic investigation><epidemiological><experience><febrile><febris><field based data><field learning><field study><field test><flexibility><flexible><genetic epidemiologic study><genetic epidemiology><genomic epidemiology><improved><improved outcome><incomes><infection burden><infectious disease transmission><interdisciplinary approach><interest><intervention efficacy><investigate epidemiology><investigate longitudinal><leadership development><longitudinal investigation><longitudinal research><method development><multidisciplinary approach><new approaches><next gen sequencing><next generation><next generation sequencing><nextgen sequencing><novel approaches><novel strategies><novel strategy><ontogeny><pathogen><patient oriented research><patient oriented study><pilot study><programs><public health intervention><respiratory pathogen><respiratory virus><response><serology surveillance><serosurveillance><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><skills><study epidemiology><study longitudinal><success><survey epidemiology><survey longitudinal><therapeutic efficacy><therapy efficacy><tool><translation research><translational investigation><translational investigator><translational researcher><translational scientist><transmission process>
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Michal L Melamed

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Exploratory lead · 18/100
Active award
Career award
$165,191
FY 2025

Project Title

Mentoring in Kidney Health

Grant Number:

5K26DK138488-04

Activity Code:

K26

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/7/2023

End Date:

5/31/2028

Project Abstract

Dr. Melamed is an internationally known kidney health investigator and award-winning mentor. She has mentored 16 post-doctoral fellows in Internal Medicine and Pediatric Nephrology. Her earliest trainees currently hold R-level grants from the NIH. She has published over 140 papers in the medical lit...

Research Terms

<21+ years old><Adult><Adult Human><Advisory Committees><American><Area><Award><Baking Soda><Biological Markers><Carbonic Acid Monosodium Salt><Caring><Childhood><Cities><Clinical><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Community Health Aides><Data><Dialysis><Dialysis procedure><Educational workshop><Faculty><Fellowship Program><Funding><Grant><Health><Hematology><Hemodialyses><Hemodialysis><History><Home><Hospital Admission><Hospitalization><Institution><Internal Medicine><International><Investigators><K12><K12 Award><K12 Mechanism><K12 Program><Kidney><Kidney Diseases><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Leadership><Literature><MD students><Medical><Medical Students><Medical center><Medicine><Mentored Clinical Scientist Development Program><Mentors><Mentorship><Metabolic acidosis><Methods><Modality><Modeling><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nephrology><Nephropathy><New York><New York City><Outcome><Paper><Pathway interactions><Patients><Personal Satisfaction><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D. student><PhD student><PhD. student><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Publishing><Qualifying><Recording of previous events><Renaissance><Renal Disease><Renal Grafting><Renal Transplantation><Renal Transplants><Reporting><Research><Research Associate><Research Personnel><Research Training><Researchers><Role><Seasons><Societies><Sodium Bicarbonate><Sodium Hydrogen Carbonate><Spottings><TL1><TNF Ligand-Related Molecule 1><TNF15><TNFSF15><TNFSF15 gene><Task Forces><Time><Training><Tumor Necrosis Factor Ligand Superfamily Member 15><United States National Institutes of Health><Universities><VEGI><Vascular Endothelial Growth Inhibitor><Vascular calcification><Work><Workshop><Writing><adulthood><advisory team><bio-markers><biologic marker><biomarker><bone><bone health><career><career development><clinical epidemiology><college><collegiate><community health worker><conference><convention><design><designing><dialysis therapy><doctoral student><experience><female faculty><health and care delivery><health care delivery><health delivery systems><health services delivery><histories><homes><improved><innovate><innovation><innovative><kidney disorder><kidney tx><leadership development><medical college><medical school students><medical schools><meeting><meetings><member><next generation><novel><pathway><pediatric><peer coaching><peer instruction><peer led team learning><peer mentoring><peer teaching><post-doc><post-doctoral><post-doctoral trainee><pre-doc><pre-doctoral><programs><randomized placebo control trial><randomized placebo controlled trial><renal><renal disorder><research associates><responsible research conduct><school of medicine><secondary analysis><skills><social role><summit><symposia><symposium><undergrad><undergraduate><undergraduate student><urologic><urological><well-being><wellbeing><women faculty>
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Scott K Heysell

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

Exploratory lead · 18/100
Active award
Career award
$146,170
FY 2025

Project Title

A global Infectious diseases framework to grow interdisciplinary research

Grant Number:

1K24AI187675-01

Activity Code:

K24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/9/2025

End Date:

4/30/2030

Project Abstract

PROJECT SUMMARY / ABSTRACT In non-pandemic periods, tuberculosis (TB) is the leading killer from a single infectious pathogen, despite curative antibiotics. Malnutrition, both undernutrition and poor nutrition leading to conditions such as diabetes mellitus, is the largest risk factor for TB disease...

Research Terms

<AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Active Follow-up><Address><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Antitubercular Agents><Biological><COVID-19><CV-19><Cessation of life><Clinical><Clinical Data><Clinical Research><Clinical Study><Clinical Trials><Communicable Diseases><Communities><Coronavirus Infectious Disease 2019><Critical Illness><Critically Ill><Data Science><Death><Dedications><Development><Diabetes Mellitus><Dietary Intervention><Discipline><Disease><Disorder><Economics><Education><Educational aspects><Educational workshop><Engineering><Epidemic><Epidemiology><Evaluation><Faculty><Faculty Education><Faculty Training><Familiarity><Food><Funding><Funding Agency><Funding Source><Generalized Growth><Geography><Grant><Growth><HIV><HIV/Mtb><HIV/TB><HIV/mycobacterium tuberculosis><HIV/tuberculosis><History><Household><Human Immunodeficiency Viruses><Impoverished><Incidence><Individual><Infection><Infectious Diseases><Infectious Disorder><Interdisciplinary Research><Interdisciplinary Study><International><Intervention><Investigators><Knowledge><LAV-HTLV-III><Language><Lead><Leadership><Lymphadenopathy-Associated Virus><M tb><M tuberculosis><M tuberculosis infection><M. tb><M. tb infection><M. tuberculosis><M. tuberculosis infection><M. tuberculosis/HIV><M.tb infection><M.tuberculosis infection><MTB infection><Malnutrition><Measurement><Mentors><Mentorship><Methodology><Miscellaneous Antibiotic><Multidisciplinary Collaboration><Multidisciplinary Research><Mycobacterium tuberculosis><Mycobacterium tuberculosis (MTB) infection><Mycobacterium tuberculosis infection><NIH><Names><National Institutes of Health><Nutrition><Nutrition Interventions><Nutritional Deficiency><Nutritional Interventions><Pathway interactions><Pb element><Persons><Pharmacodynamics><Pharmacology><Phase><Physicians><Policies><Population><Population Attributable Risks><Postdoc><Postdoctoral Fellow><Poverty><Randomized><Randomized, Controlled Trials><Recording of previous events><Recovery of Function><Regimen><Regulation><Research><Research Associate><Research Personnel><Research Specimen><Researchers><Risk Factors><Role><Sanitary Engineering><Schools><Science><Scientist><South Africa><Specimen><Structure><Students><TB infection><Tanzania><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Techniques><Time><Tissue Growth><Toxic effect><Toxicities><Training><Training Programs><Treatment outcome><Tuberculosis><Tuberculostatic Agents><Undernutrition><United States National Institutes of Health><Universities><Vaccines><Virginia><Virus-HIV><Vulnerable Populations><Work><Workshop><Writing><active followup><anti-TB><anti-microbial><anti-tuberculosis><antiTB><antimicrobial><arm><assay development><attributable fraction><biologic><career><compare to control><comparison control><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><design><designing><developmental><diabetes><diagnostic assay><diagnostic development><diet intervention><dietary><dietary deficiency><disseminated TB><disseminated tuberculosis><economic><enteral pathogen><enteric dysbiosis><enteric pathogen><enteropathogen><epidemiologic><epidemiological><experience><faculty development><faculty professional development><follow up><follow-up><followed up><followup><food security><functional recovery><global health><health equity><heavy metal Pb><heavy metal lead><histories><implementation science><improved><infection due to Mycobacterium tuberculosis><innovate><innovation><innovative><instructor training><inter-institutional><interdisciplinary collaboration><intestinal pathogen><intestine pathogen><malleable risk><malnourished><metabolism measurement><metabolomics><metabonomics><modifiable risk><mtb><name><named><naming><new approaches><novel><novel approaches><novel strategies><novel strategy><nutrition deficiency><nutrition deficiency disorder><nutritional deficiency disorder><ontogeny><pathogen><pathway><patient centered><patient oriented><peer><point of care><post-doc><post-doctoral><post-doctoral trainee><programs><randomisation><randomization><randomized control trial><randomly assigned><research associates><response to therapy><response to treatment><skills><social><social role><teacher development><theories><therapeutic response><therapy response><transdisciplinary collaboration><treatment response><treatment responsiveness><tuberculosis infection><tuberculous spondyloarthropathy><vaccine efficacy><vulnerable group><vulnerable individual><vulnerable people>
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NEIL A GOLDENBERG

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 18/100
Active award
Career award
$128,052
FY 2025

Project Title

Mentorship in Investigating Novel Risk Models and Prognostic Factors in Patients Less Than 21 Years Old with Venous Thromboembolism

Grant Number:

5K24HL166791-02

Activity Code:

K24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/15/2024

End Date:

1/31/2029

Project Abstract

ABSTRACT Venous thromboembolism (VTE), consisting of deep vein thrombosis (DVT) and pulmonary embolism (PE), affects approximately 1 in 200 hospitalized patients <21 years old, and annual health care costs of pediatric VTE can be estimated at $72M in the U.S. alone. As in adults, PE can be fatal in ...

Research Terms

<0-11 years old><21 year old><21 years of age><21+ years old><AHCPR><AHRQ><Acute><Acute respiratory infection><Address><Adult><Adult Human><Affect><Agency for Health Care Policy and Research><Agency for Healthcare Research and Quality><Alabama><Anticoagulant Agents><Anticoagulant Chemotherapy><Anticoagulant Drugs><Anticoagulant therapy><Anticoagulants><Anticoagulation><Antithrombotic Agents><Antithrombotic Drugs><Assay><B cell differentiation factor><B cell stimulating factor 2><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Bayesian Method><Bayesian Methodology><Bayesian Statistical Method><Bayesian approaches><Bayesian classification method><Bayesian classification procedure><Bayesian posterior distribution><Bioassay><Biological Assay><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Bleeding><Blood Plasma><Cardiac Surgery><Cardiac Surgery procedures><Caring><Catheters><Censuses><Child><Child Youth><Childhood><Children (0-21)><Chronic><Clinical><Clinical Faculty><Clinical Nurse Educator><Clinical Research><Clinical Study><Clotting><Coagulation><Coagulation Process><Cofactor Protein S><Collaborations><Collection><Committee Members><Coupled><Critical Care><Critical Illness><Critically Ill><Critically ill children><Cytolysis><Data><Data Banks><Data Collection><Data Science><Data Set><Databanks><Deep Vein Thrombosis><Deep-Venous Thrombosis><Development><Diagnosis><Discipline><Distance Learning><Doctor of Pharmacy><Dose><Drugs><Elderly><Event><Faculty><Female><Fibrinolytic Agents><Fibrinolytic Drugs><Frequencies><Funding><Future><General Prognostic Factor><Goals><HPGF><Health Care Costs><Health Costs><Heart Surgical Procedures><Hematology><Hemorrhage><Hepatocyte-Stimulating Factor><Hereditary><Hospital Admission><Hospitalization><Hospitalized Child><Hospitals><Hybridoma Growth Factor><Hypercoagulability><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Incidence><Individual><Inflammatory><Inherited><Institution><Interdisciplinary Research><Interdisciplinary Study><Interleukin-6><International><Intervention><Investigation><Investigators><Knowledge><Laboratories><Leadership><Life><Lysis><MGI-2><Measures><Mechanical ventilation><Medication><Medication Errors><Medicine><Mentors><Mentorship><Modeling><Multi-center studies><Multi-center trial><Multicenter Studies><Multicenter Trials><Multidisciplinary Collaboration><Multidisciplinary Research><Myeloid Differentiation-Inducing Protein><NHLBI><National Heart, Lung, and Blood Institute><Nurse Educator><Nursing Faculty><Nursing Staff Developer><Nursing Staff Development Specialist><Outcome><Patients><Pharm.D.><PharmD><Pharmaceutical Preparations><Pharmacies><Pharmacy facility><Phase><Plasma><Plasma Serum><Plasmacytoma Growth Factor><Play><Population Growth><Post thrombotic syndrome><Post-phlebitic Disease><Postphlebitic Disease><Postphlebitic Syndrome><Postthrombotic syndrome><Prevention><Prognostic Factor><Prognostic Marker><Prognostic/Survival Factor><Protein C><Protein S><Protein S Deficiency><Proteomics><Public Health><Publications><Publishing><Pulmonary Embolism><R-Series Research Projects><R01 Mechanism><R01 Program><Randomization trial><Recommendation><Recurrence><Recurrent><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Reticuloendothelial System, Serum, Plasma><Risk><Risk Assessment><Risk Factors><Role><Scientific Publication><Societies><Thrombase><Thrombin><Thrombolytic Agents><Thrombolytic Drugs><Thrombophilia><Time><Tracheostomy><Tracheostomy procedure><Training><Translational Research><Translational Science><United States Agency for Health Care Policy and Research><United States Agency for Healthcare Research and Quality><Universities><Venous Insufficiency><Venous ulcer-leg syndrome><Vitamin K-Dependent Protein S><Work><adult youth><adulthood><advanced age><age 21><age 21 years><age associated><age correlated><age dependent><age linked><age related><age specific><antithrombotic medication><antithrombotics><bio-markers><biobank><biologic marker><biological specimen repository><biomarker><biomarker development><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood loss><blood thinner><career><child patients><clinical significance><clinically significant><cohort><critically ill child><cytokine><data depository><data repository><data set repository><dataset repository><developmental><drug/agent><fibrinogenase><geriatric><group of color><heart surgery><improved><indexing><individual of color><inpatient care><inpatient service><interferon beta 2><kids><knowledge base><life span><lifespan><mechanical respiratory assist><mechanically ventilated><medication administration errors><member><mid life><mid-life><middle age><middle aged><midlife><multidisciplinary><novel><older adult><older adulthood><pediatric><pediatric patients><people of color><person of color><population of color><post-phlebitic syndrome><prognosis model><prognostic biomarker><prognostic indicator><prognostic model><programs><randomized trial><randomized, clinical trials><remote learning><senior citizen><skills><social role><specimen bank><specimen repository><thrombopoiesis inhibitor><translation research><translational investigation><translational investigator><translational researcher><translational scientist><twenty-one year old><twenty-one years of age><venous thromboembolism><young adult><young adult age><young adulthood><youngster><♀>
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Akiko Okifuji

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 10/100
Active award
$163,600
FY 2025

Project Title

Metformin as a novel, mechanistic treatment of fibromyalgia; a proof of concept RCT

Grant Number:

5R21AR082574-03

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2027

Project Abstract

7. PROJECT SUMMARY This is a proof of concept pilot study, a double-blinded, randomized controlled trial (RCT) to test the effect of low dose metformin on improving pain and other symptoms in patients with the fibromyalgia syndrome (FMS). FMS is a common chronic pain disorder with no cure. Current t...

Research Terms

<(hydroxymethylglutaryl-CoA reductase (NADPH)) kinase><5'-AMP-activated protein kinase><AMP-activated kinase><AMP-activated protein kinase><AMPK enzyme><Adult-Onset Diabetes Mellitus><Affect><American><Analgesia Tests><Anxiety><Basal Transcription Factor><Basal transcription factor genes><Beta Proprotein Interleukin 1><Biochemical Markers><Blood><Blood Reticuloendothelial System><Blood leukocyte><Caring><Cell Body><Cells><Chronic><Clinical><Clinical Research><Clinical Study><Cognitive Disturbance><Cognitive Impairment><Cognitive Manifestations><Cognitive Symptoms><Cognitive decline><Cognitive function abnormal><Common Rat Strains><Complex><Consent><Data><Data Bases><Databases><Development><Diabetes Mellitus><Diffuse Myofascial Pain Syndrome><Dimethylbiguanidine><Dimethylguanylguanidine><Disturbance in cognition><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drugs><Enzyme Gene><Enzymes><FK506 Binding Protein 12-Rapamycin Associated Protein 1><FKBP12 Rapamycin Complex Associated Protein 1><FRAP1><FRAP1 gene><FRAP2><Fatigue><Fibromyalgia><Fibromyositis-Fibromyalgia Syndrome><Fibrositis><Future><Gene Expression><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Transcription><Goals><HMG CoA reductase (NADPH) kinase><HMG CoA reductase kinase><HMG coenzyme A reductase (NADPH) kinase><Harm Minimization><Harm Reduction><Health Care><Hyperalgesia><Hyperalgesic Sensations><IFN-Gamma-Inducing Factor Gene><IFN-gamma-Inducing Factor><IGIF><IGIF Gene><IL-1 Gamma><IL-1 Gamma Gene><IL-1 beta><IL-1 β><IL-1-b><IL-18><IL-18 Gene><IL-1g><IL-1g Gene><IL-1β><IL1-Beta><IL1-β><IL18><IL18 Protein><IL18 gene><IL1B Protein><IL1F2><IL1F4><IL1F4 Gene><IL1β><Immune><Immunes><Impaired cognition><Inflammasome><Inflammation><Inflammatory><Insulin Resistance><Interferon-Gamma-Inducing Factor Gene><Interferon-gamma-Inducing Factor><Interleukin 18 (Interferon-Gamma-Inducing Factor)><Interleukin 18 (Interferon-Gamma-Inducing Factor) Gene><Interleukin 18 Proprotein><Interleukin 18 Proprotein Gene><Interleukin 1beta><Interleukin-1 Gamma><Interleukin-1 Gamma Gene><Interleukin-1 beta><Interleukin-18><Interleukin-18 Precursor><Interleukin-18 Precursor Gene><Interleukin-1β><Intermediary Metabolism><Ketosis-Resistant Diabetes Mellitus><Kinases><Lack of Energy><Leukocytes><Leukocytes Reticuloendothelial System><MGC12320><MGC12320 Gene><MPD syndrome><Marrow leukocyte><Maturity-Onset Diabetes Mellitus><Mechanics><Mechanistic Target of Rapamycin><Medical><Medication><Mental Depression><Messenger RNA><Metabolic><Metabolic Processes><Metabolism><Metformin><Methods><Modeling><Muscular Rheumatism><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><Neurobehavioral Manifestations><Neurobehavioral Signs and Symptoms><Neuropathy><Nociception><Nociception Tests><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Pain><Pain Assessment><Pain Control><Pain Measurement><Pain Therapy><Pain intensity><Pain management><Pain measure><Painful><Pathway interactions><Patient Self-Report><Patients><Peripheral><Pharmaceutical Preparations><Phase 2 Clinical Trials><Phase II Clinical Trials><Phenotype><Phosphorylation><Phosphotransferase Gene><Phosphotransferases><Physical Function><Pilot Projects><Placebo Effect><Placebos><Play><Polymerase Chain Reaction><Population><Pre-Clinical Model><Preclinical Models><Preinterleukin 1 Beta><Process><Productivity><Protein Phosphorylation><Public Health><QOL><Quality of life><Questionnaires><RAFT1><RNA Expression><Randomized><Randomized, Controlled Trials><Rat><Rats Mammals><Rattus><Receptor Protein><Research><Research Resources><Resources><Role><Safety><Self-Report><Severities><Sham Treatment><Sleep disturbances><Slow-Onset Diabetes Mellitus><Spinal Cord Trauma><Spinal Trauma><Spinal cord injured><Spinal cord injury><Stable Diabetes Mellitus><Symptoms><T2 DM><T2D><T2DM><Testing><Time><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Transphosphorylases><Traumatic Myelopathy><Treatment Efficacy><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><White Blood Cells><White Cell><Work><aberrant sleep><adult onset diabetes><affective disturbance><alleviate symptom><ameliorating symptom><antinociception><antinociceptive><anxiety symptoms><anxious symptom><arm><assess effectiveness><central sensitization><chronic pain condition><chronic pain disorder><chronic painful condition><chronic widespread pain><co-morbid><co-morbidity><cognitive dysfunction><cognitive loss><comorbidity><cost><cytokine><data base><decrease disability><decrease in disability><decrease symptom><depression><determine effectiveness><developmental><diabetes><disability><disability reduction><disabling symptom><disrupted sleep><disturbance in affect><disturbed sleep><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug/agent><effective therapy><effective treatment><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><examine effectiveness><expectancy effect><expectation effect><experience><fewer symptoms><fibromyalgia patients><fibromyalgia syndrome><hydroxymethylglutaryl-CoA-reductase kinase><hyperalgia><impaired sleep><improved><insulin resistant><insulin tolerance><interest><intervention efficacy><irregular sleep><ketosis resistant diabetes><lessen disability><mRNA><mTOR><mammalian target of rapamycin><maturity onset diabetes><mechanic><mechanical><minimize disability><mitigate disability><mood alteration><mood and affect disturbance><mood disturbance><mood dysfunction><mood symptom><myofascial pain dysfunction syndrome><neural inflammation><neurobehavioral symptom><neuroinflammation><neuroinflammatory><neuropathic><nocebo><nociceptive><novel><opiate consumption><opiate drug use><opiate intake><opiate use><opioid consumption><opioid drug use><opioid intake><opioid use><pain assay><pain intervention><pain relief><pain symptom><pain treatment><painful symptom><pathway><patients with fibromyalgia><phase II protocol><pilot study><placebo response><pre-clinical><pre-clinical study><preclinical><preclinical study><primary end point><primary endpoint><prospective><randomisation><randomization><randomized control trial><randomly assigned><receptor><recruit><reduce symptoms><reduction in disability><relieve pain><relieves symptoms><secondary end point><secondary endpoint><sham therapy><sleep disruption><sleep dysregulation><sleep/wake disruption><sleep/wake disturbance><slow disability><social role><symptom alleviation><symptom reduction><symptom relief><symptom treatment><symptomatic treatment><therapeutic efficacy><therapy efficacy><transcription factor><treat symptom><type 2 DM><type II DM><type two diabetes><white blood cell><white blood corpuscle>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Norman Taylor

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 10/100
Active award
$163,600
FY 2025

Project Title

Metformin as a novel, mechanistic treatment of fibromyalgia; a proof of concept RCT

Grant Number:

5R21AR082574-03

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2027

Project Abstract

7. PROJECT SUMMARY This is a proof of concept pilot study, a double-blinded, randomized controlled trial (RCT) to test the effect of low dose metformin on improving pain and other symptoms in patients with the fibromyalgia syndrome (FMS). FMS is a common chronic pain disorder with no cure. Current t...

Research Terms

<(hydroxymethylglutaryl-CoA reductase (NADPH)) kinase><5'-AMP-activated protein kinase><AMP-activated kinase><AMP-activated protein kinase><AMPK enzyme><Adult-Onset Diabetes Mellitus><Affect><American><Analgesia Tests><Anxiety><Basal Transcription Factor><Basal transcription factor genes><Beta Proprotein Interleukin 1><Biochemical Markers><Blood><Blood Reticuloendothelial System><Blood leukocyte><Caring><Cell Body><Cells><Chronic><Clinical><Clinical Research><Clinical Study><Cognitive Disturbance><Cognitive Impairment><Cognitive Manifestations><Cognitive Symptoms><Cognitive decline><Cognitive function abnormal><Common Rat Strains><Complex><Consent><Data><Data Bases><Databases><Development><Diabetes Mellitus><Diffuse Myofascial Pain Syndrome><Dimethylbiguanidine><Dimethylguanylguanidine><Disturbance in cognition><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drugs><Enzyme Gene><Enzymes><FK506 Binding Protein 12-Rapamycin Associated Protein 1><FKBP12 Rapamycin Complex Associated Protein 1><FRAP1><FRAP1 gene><FRAP2><Fatigue><Fibromyalgia><Fibromyositis-Fibromyalgia Syndrome><Fibrositis><Future><Gene Expression><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Transcription><Goals><HMG CoA reductase (NADPH) kinase><HMG CoA reductase kinase><HMG coenzyme A reductase (NADPH) kinase><Harm Minimization><Harm Reduction><Health Care><Hyperalgesia><Hyperalgesic Sensations><IFN-Gamma-Inducing Factor Gene><IFN-gamma-Inducing Factor><IGIF><IGIF Gene><IL-1 Gamma><IL-1 Gamma Gene><IL-1 beta><IL-1 β><IL-1-b><IL-18><IL-18 Gene><IL-1g><IL-1g Gene><IL-1β><IL1-Beta><IL1-β><IL18><IL18 Protein><IL18 gene><IL1B Protein><IL1F2><IL1F4><IL1F4 Gene><IL1β><Immune><Immunes><Impaired cognition><Inflammasome><Inflammation><Inflammatory><Insulin Resistance><Interferon-Gamma-Inducing Factor Gene><Interferon-gamma-Inducing Factor><Interleukin 18 (Interferon-Gamma-Inducing Factor)><Interleukin 18 (Interferon-Gamma-Inducing Factor) Gene><Interleukin 18 Proprotein><Interleukin 18 Proprotein Gene><Interleukin 1beta><Interleukin-1 Gamma><Interleukin-1 Gamma Gene><Interleukin-1 beta><Interleukin-18><Interleukin-18 Precursor><Interleukin-18 Precursor Gene><Interleukin-1β><Intermediary Metabolism><Ketosis-Resistant Diabetes Mellitus><Kinases><Lack of Energy><Leukocytes><Leukocytes Reticuloendothelial System><MGC12320><MGC12320 Gene><MPD syndrome><Marrow leukocyte><Maturity-Onset Diabetes Mellitus><Mechanics><Mechanistic Target of Rapamycin><Medical><Medication><Mental Depression><Messenger RNA><Metabolic><Metabolic Processes><Metabolism><Metformin><Methods><Modeling><Muscular Rheumatism><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><Neurobehavioral Manifestations><Neurobehavioral Signs and Symptoms><Neuropathy><Nociception><Nociception Tests><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Pain><Pain Assessment><Pain Control><Pain Measurement><Pain Therapy><Pain intensity><Pain management><Pain measure><Painful><Pathway interactions><Patient Self-Report><Patients><Peripheral><Pharmaceutical Preparations><Phase 2 Clinical Trials><Phase II Clinical Trials><Phenotype><Phosphorylation><Phosphotransferase Gene><Phosphotransferases><Physical Function><Pilot Projects><Placebo Effect><Placebos><Play><Polymerase Chain Reaction><Population><Pre-Clinical Model><Preclinical Models><Preinterleukin 1 Beta><Process><Productivity><Protein Phosphorylation><Public Health><QOL><Quality of life><Questionnaires><RAFT1><RNA Expression><Randomized><Randomized, Controlled Trials><Rat><Rats Mammals><Rattus><Receptor Protein><Research><Research Resources><Resources><Role><Safety><Self-Report><Severities><Sham Treatment><Sleep disturbances><Slow-Onset Diabetes Mellitus><Spinal Cord Trauma><Spinal Trauma><Spinal cord injured><Spinal cord injury><Stable Diabetes Mellitus><Symptoms><T2 DM><T2D><T2DM><Testing><Time><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Transphosphorylases><Traumatic Myelopathy><Treatment Efficacy><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><White Blood Cells><White Cell><Work><aberrant sleep><adult onset diabetes><affective disturbance><alleviate symptom><ameliorating symptom><antinociception><antinociceptive><anxiety symptoms><anxious symptom><arm><assess effectiveness><central sensitization><chronic pain condition><chronic pain disorder><chronic painful condition><chronic widespread pain><co-morbid><co-morbidity><cognitive dysfunction><cognitive loss><comorbidity><cost><cytokine><data base><decrease disability><decrease in disability><decrease symptom><depression><determine effectiveness><developmental><diabetes><disability><disability reduction><disabling symptom><disrupted sleep><disturbance in affect><disturbed sleep><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug/agent><effective therapy><effective treatment><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><examine effectiveness><expectancy effect><expectation effect><experience><fewer symptoms><fibromyalgia patients><fibromyalgia syndrome><hydroxymethylglutaryl-CoA-reductase kinase><hyperalgia><impaired sleep><improved><insulin resistant><insulin tolerance><interest><intervention efficacy><irregular sleep><ketosis resistant diabetes><lessen disability><mRNA><mTOR><mammalian target of rapamycin><maturity onset diabetes><mechanic><mechanical><minimize disability><mitigate disability><mood alteration><mood and affect disturbance><mood disturbance><mood dysfunction><mood symptom><myofascial pain dysfunction syndrome><neural inflammation><neurobehavioral symptom><neuroinflammation><neuroinflammatory><neuropathic><nocebo><nociceptive><novel><opiate consumption><opiate drug use><opiate intake><opiate use><opioid consumption><opioid drug use><opioid intake><opioid use><pain assay><pain intervention><pain relief><pain symptom><pain treatment><painful symptom><pathway><patients with fibromyalgia><phase II protocol><pilot study><placebo response><pre-clinical><pre-clinical study><preclinical><preclinical study><primary end point><primary endpoint><prospective><randomisation><randomization><randomized control trial><randomly assigned><receptor><recruit><reduce symptoms><reduction in disability><relieve pain><relieves symptoms><secondary end point><secondary endpoint><sham therapy><sleep disruption><sleep dysregulation><sleep/wake disruption><sleep/wake disturbance><slow disability><social role><symptom alleviation><symptom reduction><symptom relief><symptom treatment><symptomatic treatment><therapeutic efficacy><therapy efficacy><transcription factor><treat symptom><type 2 DM><type II DM><type two diabetes><white blood cell><white blood corpuscle>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lixin Wang

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

Exploratory lead · 10/100
Active award
$155,896
FY 2025

Project Title

Definition and perturbation of cell-regulatory heterogeneities in solid tumors

Grant Number:

5R50CA265089-05

Activity Code:

R50

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/22/2021

End Date:

8/31/2026

Project Abstract

ABSTRACT Cell-state variation in cancer is important for tumor initiation–progression and creates a major hurdle to effective anticancer therapeutics. Unbiased methods are needed to monitor single-cell regulatory states of cancer cells in situ, as are approaches to analyze these data and generate ac...

Research Terms

<3D cell culture><3D culture><Acceleration><Acute><Award><Breast Epithelial Cells><Cancer Biology><Cancers><Cell Body><Cells><Collaborations><Cooperative Agreements><Data><Ensure><ErbB2 receptor><Genes><Heterogeneity><Heterograft><Heterologous Transplantation><In Situ><In vivo analysis><Lead><Ligands><Malignant Cell><Malignant Neoplasms><Malignant Tumor><Measures><Methods><Mice><Mice Mammals><Modernization><Molecular Cloning><Molecular Genetics><Monitor><Murine><Mus><Oncogene Protein HER-2><PTK Receptors><Pb element><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D. student><PhD student><PhD. student><Proto-Oncogene Protein HER-2><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Seq><RNA sequencing><RNAseq><Receptor Protein-Tyrosine Kinases><Receptor Tyrosine Kinase Gene><Research><Research Activity><Research Grants><Research Project Grants><Research Projects><Research Support><Scientist><Solid Neoplasm><Solid Tumor><Systems Biology><Techniques><Technology><Training><Transmembrane Receptor Protein Tyrosine Kinase><Tyrosine Kinase Linked Receptors><Tyrosine Kinase Receptors><U-Series Cooperative Agreements><UVA Cancer Center><Universities><University of Virginia Cancer Center><Variant><Variation><Virginia><Xenograft><Xenograft procedure><Xenotransplantation><anti-cancer research><anti-cancer therapeutic><cancer cell><cancer research><doctoral student><epigenomics><erbB-2 Proto-Oncogene Protein><erbB-2 Receptor><heavy metal Pb><heavy metal lead><in vivo evaluation><in vivo testing><laser capture microdissection><malignancy><mammary epithelial cells><mammary gland epithelial cells><neoplasm/cancer><neu Receptor><pre-doc><pre-doctoral><skills><stem><three dimensional cell culture><transcriptome profiling><transcriptome sequencing><transcriptomic profiling><transcriptomic sequencing><tumor><tumor initiation><xeno-transplant><xeno-transplantation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

THOMAS JACK SCHNITZER

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Exploratory lead · 10/100
Active award
$114,733
FY 2025

Project Title

Denosumab and sequential zoledronic acid to prevent bone loss and maintain bone mass after spinal cord injury

Grant Number:

5R34AR082859-02

Activity Code:

R34

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2024

End Date:

7/31/2026

Project Abstract

The current R34 proposal in response to NIAMS PAR-22-205 will provide us the time and resources to complete the detailed clinical trial planning necessary to meet NIAMS and NIH standards and regulatory requirements prior to submitting a U01 application for funding. Activities included in this propos...

Research Terms

<2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosphonic acid><Acute><Antibodies><Applications Grants><Biological Markers><Bisphosphonates><Blinded><Blood Serum><Bone Resorption><Booklets><Brochures><Budgets><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Case Report Form><Certification><Clinical><Clinical Trials><Communities><Complex><Computed Tomography><Conduct Clinical Trials><Consent Documents><Consent Forms><Contracting Opportunities><Contracts><Coxa><DEXA><DXA><Data><Data Analyses><Data Analysis><Data Bases><Data Collection><Databases><Development><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Ensure><Event><Failure><Fracture><Funding><Funding Opportunities><Goals><Grant><Grant Proposals><Hip><Hip region structure><IND Filing><IND application><IND package><IND submission><IRB><IRBs><IV Infusion><Image><Imaging technology><Individual><Informed Consent Documents><Informed Consent Forms><Institution><Institutional Review Boards><Intervention><Intravenous infusion procedures><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Investigators><Knee><Leadership><Lesion><Load Bearing><Lower Extremity><Lower Limb><Measurement><Measures><Mediation><Medical Rehabilitation><Membrum inferius><Mission><Monitor><NIAMS><NIH><National Institute of Arthritis, and Musculoskeletal, and Skin Diseases><National Institutes of Health><Negotiating><Negotiation><Neurologic><Neurological><ODF factor><OPGL protein><Osteoclast Differentiation Factor><Osteoclastic Bone Loss><Osteoprotegerin Ligand><Outcome><Pamphlets><Participant><Patients><Persons><Phase><Placebos><Population><Postmenopausal Osteoporosis><Preparation><Procedures><Protocol><Protocols documentation><Publishing><RANK ligand><Randomized><Receptor Activator of Nuclear Factor Kappa B Ligand><Rehabilitation><Rehabilitation therapy><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Safety><Sample Size><Sequential Treatment><Serum><Sham Treatment><Site><Spinal Cord Trauma><Spinal Trauma><Spinal cord injured><Spinal cord injury><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><TNF-Related Activation-Induced Cytokine><TRANCE protein><Testing><Time><Tomodensitometry><Training><Traumatic Myelopathy><Tumor Necrosis Factor Ligand Superfamily Member 11><United States National Institutes of Health><Weight Bearing><Weight-Bearing state><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><Zoledronic Acid><bio-markers><biologic marker><biomarker><biphosphonate><bisphosphonate><bone><bone fracture><bone loss><bone loss prevention><bone mass><bone strength><catscan><clinical decision-making><clinical efficacy><clinical research site><clinical site><comparable efficacy><comparative efficacy><compare efficacy><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><data base><data integration><data interpretation><data management><data standardization><data standards><design><designing><determine efficacy><developmental><diphosphonate><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy study><evaluate efficacy><examine efficacy><experience><fracture risk><imaging><inhibitor><intravenous administration><intravenous infusion><meeting><meetings><member><non-contrast CT><noncontrast CT><noncontrast computed tomography><operation><operations><preparations><prevent><prevent bone loss><preventing><randomisation><randomization><randomized, clinical trials><randomly assigned><recruit><rehab therapy><rehabilitative><rehabilitative therapy><response><safety study><sham therapy><skeletal><statistical analysis><timeline><trial design><trial planning>
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Prabodh Kumar Pandey

UNIVERSITY OF CALIFORNIA-IRVINE, IRVINE, CA

Exploratory lead · 10/100
Active award
$80,229
FY 2025

Project Title

Quantitative in vivo dosimetry for radiotherapy using model-based X-ray-induced acoustic computed tomography

Grant Number:

5R50CA283816-02

Activity Code:

R50

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/3/2024

End Date:

8/31/2029

Project Abstract

Abstract Accurate dose delivery at the tumor site is crucial for the success of radiotherapy (RT) for cancer treatment. However, as yet there are no techniques in clinics with the ability to monitor RT. This project proposes X-ray- induced acoustic (XA) computed tomography (XACT) to facilitate dose ...

Research Terms

<Acceleration><Acoustics><Address><Adopted><Advanced Instrumentation><Affect><Algorithms><American Cancer Society><Artifacts><Award><Biomedical Computing><Body Tissues><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Cancer Radiotherapy><Cancer Treatment><Cell Communication and Signaling><Cell Signaling><Characteristics><Clinic><Clinical><Clinical Paths><Clinical Pathways><Computed Tomography><Computer Instrumentation><Computers and Advanced Instrumentation><Creativeness><Deposit><Deposition><Dose><Funding><Goals><Grant><H+ element><Heterogeneity><Human Resources><Hydrogen Ions><Intracellular Communication and Signaling><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Manpower><Maps><Modality><Modeling><Monitor><Morphologic artifacts><NIH><National Institutes of Health><Noise><Physics><Physiologic pulse><Principal Investigator><Protons><Pulse><Qualifying><Radiation Dosimetry><Radiation therapy><Radiography><Radiometry><Radiotherapeutics><Radiotherapy><Research><Roentgen Rays><Roentgenography><Scientist><Seasons><Signal Transduction><Signal Transduction Systems><Signaling><Site><Techniques><Time><Tissues><Tomodensitometry><Transducers><Ultrasonic Transducer><Ultrasound transducer><United States National Institutes of Health><X-Radiation><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><X-Ray Radiation><X-ray><Xray><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><absorption><anti-cancer therapy><biological signal transduction><biomedical computation><biomedical imaging><cancer radiation therapy><cancer therapy><cancer-directed therapy><catscan><clinical translation><clinically translatable><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><creativity><dose information><dosimetry><experience><image construction><image generation><image reconstruction><in vivo><next generation><non-contrast CT><noncontrast CT><noncontrast computed tomography><parallelization><personnel><post-doctoral training><proton beam><proton therapy><radiation treatment><radioassay><radiological imaging><reconstruction><success><tomography><treatment with radiation><tumor>
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DINESH KHANNA

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 0/100
$99,871
FY 2025

Project Title

Planning for a Multisite Efficacy Trial of Upper Extremity Telerehabilitation for Systemic Sclerosis

Grant Number:

5R34AR082551-02

Activity Code:

R34

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/16/2024

End Date:

1/31/2026

Project Abstract

Abstract Systemic sclerosis (SSc) is a rare, chronic autoimmune connective tissue disease affecting 60,000 – 100,000 people in the US. One main driver of physical disability in patients with SSc is upper extremity (UE) limitations due to vascular and skin changes. These disease changes reduce joint ...

Research Terms

<Acceleration><Access to Care><Affect><Applications Grants><Atrophic Arthritis><Autoimmune><Blood Vessels><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Caring><Chronic><Client satisfaction><Clinical Trials><Collaborations><Communities><Comparison arm><Complication><Conduct Clinical Trials><Connective Tissue Diseases><Connective Tissue Disorder><Contracture><Cutaneous><Data><Development Plans><Diffuse><Disease><Disorder><Drug Therapy><Early Intervention><Education><Educational aspects><Effectiveness><Equity><Foundations><Geography><Goals><Grant Proposals><Hand><Health Services Accessibility><Health system><IRB><IRBs><Institutional Review Boards><Intervention><Intervention Strategies><Intervention Trial><Interventional trial><Investigators><Joints><Knowledge><Lupus><Manuals><Medical Rehabilitation><Membrum superius><Methods><Modeling><Monitor><Movement><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-site clinical trial><Multicenter clinical trial><Multisite clinical trial><Occupational Therapist><Occupational Therapy><Orphan Disease><Outcome Assessment><Pain><Painful><Patient Care><Patient Care Delivery><Patient Satisfaction><Patients><Persons><Pharmacological Treatment><Pharmacotherapy><Population><Preparation><Procedures><Process><Protocol><Protocols documentation><Provider><QOL><Quality of life><Randomized, Controlled Trials><Rare Diseases><Rare Disorder><Recommendation><Rehabilitation><Rehabilitation therapy><Reporting><Research><Research Personnel><Researchers><Rheumatoid Arthritis><Running><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Safety><Scleroderma><Self Management><Services><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severity of illness><Site><Skin><Specialist><Specialty><Structure><System><Systemic Scleroderma><Systemic Sclerosis><Testing><Therapeutic Intervention><Training><Translations><Travel><Upper Extremity><Upper Limb><Work><acceptability and feasibility><access to health services><access to services><access to treatment><accessibility to health services><arm><arm function><arm functionality><availability of services><barriers to implementation><body movement><care access><care for patients><care of patients><caring for patients><clinical practice><clinical trial protocol><community clinic><comparator arm><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><data management><delivered remotely><dermatosclerosis><design><designing><determine efficacy><disability><disease severity><drug intervention><drug treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><efficacy trial><evaluate efficacy><evidence base><examine efficacy><experience><functional improvement><functional loss><hands><health service access><health services availability><high risk><implementation barriers><implementation challenges><implementation intervention><improve function><improved><improved functional outcomes><intervention therapy><joint mobility><joint mobilization><joint movement><manage symptom><medical specialties><mobile app><mobile application><mobile device application><multi-site trial><multisite trial><operation><operations><orphan disorder><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><physical disability><physically disabled><physically handicapped><pilot test><practice setting><preparations><prevent><preventing><programs><progressive systemic sclerosis><randomized control trial><randomized, clinical trials><rare condition><rare syndrome><recruit><rehab therapy><rehabilitation service><rehabilitative><rehabilitative therapy><remote delivery><rheumatic arthritis><service availability><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><symptom management><telehealth><telerehab><telerehabilitation><translation><treatment access><vascular>
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Susan L. Murphy

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 0/100
$99,871
FY 2025

Project Title

Planning for a Multisite Efficacy Trial of Upper Extremity Telerehabilitation for Systemic Sclerosis

Grant Number:

5R34AR082551-02

Activity Code:

R34

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/16/2024

End Date:

1/31/2026

Project Abstract

Abstract Systemic sclerosis (SSc) is a rare, chronic autoimmune connective tissue disease affecting 60,000 – 100,000 people in the US. One main driver of physical disability in patients with SSc is upper extremity (UE) limitations due to vascular and skin changes. These disease changes reduce joint ...

Research Terms

<Acceleration><Access to Care><Affect><Applications Grants><Atrophic Arthritis><Autoimmune><Blood Vessels><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Caring><Chronic><Client satisfaction><Clinical Trials><Collaborations><Communities><Comparison arm><Complication><Conduct Clinical Trials><Connective Tissue Diseases><Connective Tissue Disorder><Contracture><Cutaneous><Data><Development Plans><Diffuse><Disease><Disorder><Drug Therapy><Early Intervention><Education><Educational aspects><Effectiveness><Equity><Foundations><Geography><Goals><Grant Proposals><Hand><Health Services Accessibility><Health system><IRB><IRBs><Institutional Review Boards><Intervention><Intervention Strategies><Intervention Trial><Interventional trial><Investigators><Joints><Knowledge><Lupus><Manuals><Medical Rehabilitation><Membrum superius><Methods><Modeling><Monitor><Movement><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-site clinical trial><Multicenter clinical trial><Multisite clinical trial><Occupational Therapist><Occupational Therapy><Orphan Disease><Outcome Assessment><Pain><Painful><Patient Care><Patient Care Delivery><Patient Satisfaction><Patients><Persons><Pharmacological Treatment><Pharmacotherapy><Population><Preparation><Procedures><Process><Protocol><Protocols documentation><Provider><QOL><Quality of life><Randomized, Controlled Trials><Rare Diseases><Rare Disorder><Recommendation><Rehabilitation><Rehabilitation therapy><Reporting><Research><Research Personnel><Researchers><Rheumatoid Arthritis><Running><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Safety><Scleroderma><Self Management><Services><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severity of illness><Site><Skin><Specialist><Specialty><Structure><System><Systemic Scleroderma><Systemic Sclerosis><Testing><Therapeutic Intervention><Training><Translations><Travel><Upper Extremity><Upper Limb><Work><acceptability and feasibility><access to health services><access to services><access to treatment><accessibility to health services><arm><arm function><arm functionality><availability of services><barriers to implementation><body movement><care access><care for patients><care of patients><caring for patients><clinical practice><clinical trial protocol><community clinic><comparator arm><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><data management><delivered remotely><dermatosclerosis><design><designing><determine efficacy><disability><disease severity><drug intervention><drug treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><efficacy trial><evaluate efficacy><evidence base><examine efficacy><experience><functional improvement><functional loss><hands><health service access><health services availability><high risk><implementation barriers><implementation challenges><implementation intervention><improve function><improved><improved functional outcomes><intervention therapy><joint mobility><joint mobilization><joint movement><manage symptom><medical specialties><mobile app><mobile application><mobile device application><multi-site trial><multisite trial><operation><operations><orphan disorder><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><physical disability><physically disabled><physically handicapped><pilot test><practice setting><preparations><prevent><preventing><programs><progressive systemic sclerosis><randomized control trial><randomized, clinical trials><rare condition><rare syndrome><recruit><rehab therapy><rehabilitation service><rehabilitative><rehabilitative therapy><remote delivery><rheumatic arthritis><service availability><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><symptom management><telehealth><telerehab><telerehabilitation><translation><treatment access><vascular>
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Sanja Schreiber

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 0/100
$87,372
FY 2025

Project Title

Planning grant for a randomized controlled trial of scoliosis-specific physiotherapy for adolescent idiopathic scoliosis

Grant Number:

5R34AR083625-02

Activity Code:

R34

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2026

Project Abstract

PROJECT SUMMARY/ABSTRACT Adolescent idiopathic scoliosis (AIS) is a spinal deformity of unknown etiology, resulting in rotation and abnormal curvature. Associated physical signs include uneven shoulders and waist, rib and flank protrusions, as well as hip misalignment. Scoliosis also affects psychol...

Research Terms

<0-11 years old><21+ years old><Acceleration><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Affect><Anatomic Abnormality><Anatomical Abnormality><Area><Award><Bleeding><Care Givers><Caregivers><Caring><Case Report Form><Causality><Certification><Child><Child Welfare><Child Youth><Childhood><Children (0-21)><Clinical Trials><Coxa><Data><Deceleration><Deformity><Development><Disproportionate number of females><Disproportionate number of women><Disproportionately affects females><Disproportionately affects women><Disproportionately impacts females><Disproportionately impacts women><Disproportionately in females><Disproportionately in women><Emotional well being><Etiology><Evaluation><Exercise><Family><Feels well><Female><Funding><General Radiology><Generalized Growth><Goals><Grant><Growth><Growth and Development><Growth and Development function><Health><Health Care Providers><Health Insurance><Health Personnel><Hemorrhage><Hip><Hip region structure><IRB><IRBs><Idiopathic scoliosis><Infection><Institutional Review Boards><Insurance Coverage><Insurance Status><Intervention><Investigators><Level of Evidence><Long-term Follow-up><Manuals><Measurement><Mental Health><Mental Hygiene><Modernization><Monitor><Morphology><Motor><Musculoskeletal><NIAMS><National Institute of Arthritis, and Musculoskeletal, and Skin Diseases><Nature><Neurologic><Neurological><Normal mental condition><Normal mental state><Normal psyche><Operative Procedures><Operative Surgical Procedures><Orthopedic><Orthopedic Surgical Profession><Orthopedics><Orthosis><Orthotic Devices><Outcome><Pain><Painful><Participant><Patient Observation><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Pattern><Personal awareness><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical therapy><Physiotherapy><Preparation><Procedures><Protocol><Protocols documentation><Pseudarthrosis><Pseudoarthrosis><Psychological Health><Psychological Well Being><Publishing><QOL><Quality of life><Radiology><Radiology Specialty><Randomized><Randomized, Controlled Trials><Recommendation><Reoperation><Repeat Surgery><Reporting><Research><Research Personnel><Researchers><Respiratory physiology><Ribs><Risk><Risk Reduction><Roentgen Rays><Rotation><Safety><Self Perception><Self image><Self view><Sense of well-being><Shoulder><Site><Spinal><Spinal Column><Spinal Diseases><Spinal Fusion><Spine><Spondylosyndeses><Strategic Planning><Supervision><Surgeon><Surgical><Surgical Interventions><Surgical Procedure><System><Testing><Therapeutic Intervention><Time><Tissue Growth><Traction><U.S. Preventative Services Task Force><U.S. Preventative Task Force><U.S. Preventive Services Task Force><U.S. Preventive Task Force><US Preventative Services Task Force><US Preventative Task Force><US Preventive Health Services Task Force><US Preventive Services Task Force><US Preventive Task Force><USPSTF><United States Preventative Services Task Force><United States Preventative Task Force><United States Preventive Services Task Force><United States Preventive Task Force><Vertebral column><Watchful Waiting><Well in self><X-Radiation><X-Ray Radiation><X-ray><Xray><adolescent welfare><adulthood><arm><backbone><blood loss><causation><child well being><child wellbeing><clinical trial protocol><common treatment><cost><design><designing><determine efficacy><developmental><disability><disease causation><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><electronic data><electronic data capture system><emotional wellbeing><emotional wellness><evaluate efficacy><evidence base><examine efficacy><female bias><female predominance><female preponderance><functional improvement><health care personnel><health care worker><health insurance plan><health provider><health workforce><improve function><improved><improved functional outcomes><improved outcome><intervention arm><intervention effect><intervention therapy><juvenile><juvenile human><kids><life span><lifespan><locomotor learning><long-term followup><male><medical personnel><mental well-being><mental wellbeing><mental wellness><motor control><motor learning><neglect><old age><ontogeny><orthotics><pain reduction><pediatric><predominance in females><predominance in women><preparations><prevent><preventing><primary outcome><psychological wellbeing><psychological wellness><psychosocial well-being><psychosocial wellbeing><psychosocial wellness><public health relevance><randomisation><randomization><randomized control trial><randomly assigned><recommended screening><recruit><reduce pain><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><respiratory function><rib bone structure><risk-reducing><scoliosis><screening guidelines><screening recommendations><secondary outcome><self awareness><self knowledge><self wellness><sense of wellbeing><spine disorder><standard of care><surgery><treatment arm><treatment guidelines><treatment provider><women's predominance><women's preponderance><youngster><♀><♂>
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Emily Catherine Somers

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 0/100
$87,372
FY 2025

Project Title

Planning grant for a randomized controlled trial of scoliosis-specific physiotherapy for adolescent idiopathic scoliosis

Grant Number:

5R34AR083625-02

Activity Code:

R34

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2026

Project Abstract

PROJECT SUMMARY/ABSTRACT Adolescent idiopathic scoliosis (AIS) is a spinal deformity of unknown etiology, resulting in rotation and abnormal curvature. Associated physical signs include uneven shoulders and waist, rib and flank protrusions, as well as hip misalignment. Scoliosis also affects psychol...

Research Terms

<0-11 years old><21+ years old><Acceleration><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Affect><Anatomic Abnormality><Anatomical Abnormality><Area><Award><Bleeding><Care Givers><Caregivers><Caring><Case Report Form><Causality><Certification><Child><Child Welfare><Child Youth><Childhood><Children (0-21)><Clinical Trials><Coxa><Data><Deceleration><Deformity><Development><Disproportionate number of females><Disproportionate number of women><Disproportionately affects females><Disproportionately affects women><Disproportionately impacts females><Disproportionately impacts women><Disproportionately in females><Disproportionately in women><Emotional well being><Etiology><Evaluation><Exercise><Family><Feels well><Female><Funding><General Radiology><Generalized Growth><Goals><Grant><Growth><Growth and Development><Growth and Development function><Health><Health Care Providers><Health Insurance><Health Personnel><Hemorrhage><Hip><Hip region structure><IRB><IRBs><Idiopathic scoliosis><Infection><Institutional Review Boards><Insurance Coverage><Insurance Status><Intervention><Investigators><Level of Evidence><Long-term Follow-up><Manuals><Measurement><Mental Health><Mental Hygiene><Modernization><Monitor><Morphology><Motor><Musculoskeletal><NIAMS><National Institute of Arthritis, and Musculoskeletal, and Skin Diseases><Nature><Neurologic><Neurological><Normal mental condition><Normal mental state><Normal psyche><Operative Procedures><Operative Surgical Procedures><Orthopedic><Orthopedic Surgical Profession><Orthopedics><Orthosis><Orthotic Devices><Outcome><Pain><Painful><Participant><Patient Observation><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Pattern><Personal awareness><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical therapy><Physiotherapy><Preparation><Procedures><Protocol><Protocols documentation><Pseudarthrosis><Pseudoarthrosis><Psychological Health><Psychological Well Being><Publishing><QOL><Quality of life><Radiology><Radiology Specialty><Randomized><Randomized, Controlled Trials><Recommendation><Reoperation><Repeat Surgery><Reporting><Research><Research Personnel><Researchers><Respiratory physiology><Ribs><Risk><Risk Reduction><Roentgen Rays><Rotation><Safety><Self Perception><Self image><Self view><Sense of well-being><Shoulder><Site><Spinal><Spinal Column><Spinal Diseases><Spinal Fusion><Spine><Spondylosyndeses><Strategic Planning><Supervision><Surgeon><Surgical><Surgical Interventions><Surgical Procedure><System><Testing><Therapeutic Intervention><Time><Tissue Growth><Traction><U.S. Preventative Services Task Force><U.S. Preventative Task Force><U.S. Preventive Services Task Force><U.S. Preventive Task Force><US Preventative Services Task Force><US Preventative Task Force><US Preventive Health Services Task Force><US Preventive Services Task Force><US Preventive Task Force><USPSTF><United States Preventative Services Task Force><United States Preventative Task Force><United States Preventive Services Task Force><United States Preventive Task Force><Vertebral column><Watchful Waiting><Well in self><X-Radiation><X-Ray Radiation><X-ray><Xray><adolescent welfare><adulthood><arm><backbone><blood loss><causation><child well being><child wellbeing><clinical trial protocol><common treatment><cost><design><designing><determine efficacy><developmental><disability><disease causation><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><electronic data><electronic data capture system><emotional wellbeing><emotional wellness><evaluate efficacy><evidence base><examine efficacy><female bias><female predominance><female preponderance><functional improvement><health care personnel><health care worker><health insurance plan><health provider><health workforce><improve function><improved><improved functional outcomes><improved outcome><intervention arm><intervention effect><intervention therapy><juvenile><juvenile human><kids><life span><lifespan><locomotor learning><long-term followup><male><medical personnel><mental well-being><mental wellbeing><mental wellness><motor control><motor learning><neglect><old age><ontogeny><orthotics><pain reduction><pediatric><predominance in females><predominance in women><preparations><prevent><preventing><primary outcome><psychological wellbeing><psychological wellness><psychosocial well-being><psychosocial wellbeing><psychosocial wellness><public health relevance><randomisation><randomization><randomized control trial><randomly assigned><recommended screening><recruit><reduce pain><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><respiratory function><rib bone structure><risk-reducing><scoliosis><screening guidelines><screening recommendations><secondary outcome><self awareness><self knowledge><self wellness><sense of wellbeing><spine disorder><standard of care><surgery><treatment arm><treatment guidelines><treatment provider><women's predominance><women's preponderance><youngster><♀><♂>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Aliza Pham Wingo

VA NORTHERN CALIFORNIA HEALTH CARE SYS, MATHER, CA

Exploratory lead · 0/100
$0
FY 2025

Project Title

BLR&D Research Career Development Transition Award Application

Grant Number:

5IK4BX005219-06

Activity Code:

IK4

Mechanism:

Other

Agency:

VA

Start Date:

10/1/2020

End Date:

9/30/2025

Project Abstract

The applicant, Aliza Wingo, M.D., M.Sc., is a board-certified psychiatrist and principal investigator at the Atlanta VA Medical Center. The first focus of Dr. Wingo’s research is to identify the genetic and molecular contributors to psychological resilience, PTSD, and depression, respectively. She i...

Research Terms

<AD dementia><Address><Affect><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Amentia><Anxiety><Area><Autopsy><Award><Awareness><Behavioral><Biologic Models><Biologic Psychiatry><Biological Models><Biological Psychiatry><Blood><Blood Reticuloendothelial System><Board Certification><Brain><Brain Nervous System><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Causality><Chromosome 1><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Communication><Complex><DICER Gene><DICER1><DICER1 gene><Data><Data Set><Dementia><Development><Disturbance in cognition><Doctor of Medicine><Elderly><Elderly depression><Encephalon><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Etiology><Event><Female><Formulation><Funding><Future><GWA study><GWAS><Gene variant><Genes><Genetic><Genetic study><Genomic medicine><Genotype><Goals><HERNA><Health><Health Care><Helicase with RNase Motif><Helicase-MOI><Human><Impaired cognition><Individual><Intervention><Investigators><Journals><K-Awards><K-Series Research Career Programs><K12H4.8-Like><KIAA0928><Life><Life Experience><M.D.><Magazine><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Meaning and purpose><Medical center><Mental Depression><Messenger RNA><Meta-Analysis><MicroRNAs><Model System><Modeling><Modern Man><Molecular><Multiomic Data><NIH><NIMH><National Institute of Mental Health><National Institutes of Health><Nature><Neurobiology><Outcome><PTSD><Paper><Participant><Pathway interactions><Patient Care><Patient Care Delivery><Post-Traumatic Neuroses><Post-Traumatic Stress Disorders><Posttraumatic Neuroses><Prefrontal Cortex><Pregnant Women><Primary Senile Degenerative Dementia><Principal Investigator><Proteins><Proteome><Proteomics><Psyche structure><Psychiatrist><Psychiatry><Publications><Publishing><Regulation><Research><Research Career Program><Research Personnel><Research Priority><Researchers><Role><Scientific Publication><Seminal><Shapes><Stress><Symptoms><Systems Biology><Techniques><Transition Career Development Award><Transition Career Development Award (K22)><Translating><Trauma><United States National Institutes of Health><Veterans><Weight><Woman><Work><advanced age><allelic variant><brain tissue><build resilience><build resiliency><care for patients><care of patients><career><caring for patients><causation><co-morbid depression><co-morbid with depression><co-morbidity with depression><cognitive dysfunction><cognitive loss><comorbid depression><comorbid with depression><comorbidity with depression><coping><dementia risk><depression><depression co-morbidity><depression comorbidity><develop resilience><develop resiliency><developmental><disease causation><effective intervention><enhance resilience><enhance resiliency><epidemiologic investigation><epidemiology study><expectant mother><expectant women><expecting mother><expecting women><experience><facilitate resilience><genetic variant><genome medicine><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic variant><geriatric><geriatric depression><global gene expression><global transcription profile><high risk><improve resilience><improve resiliency><increase resilience><increase resiliency><indicators of resilience><individuals who are pregnant><innovate><innovation><innovative><intergenerational><late life depression><later in life><later life><mRNA><mRNA Expression><marker of biological resilience><markers underlying resilience><mental><miRNA><multiomics><multiple omic data><multiple omics><necropsy><neurobiological><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutics><new therapy><new therapy approaches><new treatment approach><new treatment strategy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutics><novel therapy><novel therapy approach><offspring><panomics><pathway><people who are pregnant><positive emotion><positive emotional state><post-trauma stress disorder><postmortem><posttrauma stress disorder><pregnant females><pregnant mothers><pregnant people><pregnant populations><primary degenerative dementia><programs><promote resilience><promote resiliency><protective effect><protein expression><psychologic><psychological><resilience><resilience biomarker><resilience development><resilience marker><resilient><risk factor for dementia><risk for dementia><senile dementia of the Alzheimer type><senior citizen><signatures of resilience><social role><statistics><those who are pregnant><transcriptome><transcriptomics><traumatic neurosis><weights><whole genome association analysis><whole genome association study><women who are pregnant><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Search NIH grants by PI name

Looking for a specific principal investigator? The keyword search above looks up funded projects by topic. To search NIH grants by PI name (last name, first + last name, or partial name) and see every active and recent NIH award for that researcher, use the dedicated PI Funding Status tool.

How to Use PI Funding Data for Career Decisions

Finding the right principal investigator is one of the most important decisions in an academic career. Whether you are a postdoc looking for a mentor, a graduate student choosing a rotation lab, or a collaborator seeking a co-PI, NIH funding data provides objective signals about which investigators have active research programs and resources to support new team members.

A PI with a recently awarded R01 or equivalent grant is more likely to have budget for new personnel than one whose funding ended two years ago. The activity code tells you the type of grant: R01 and R35 awards typically support multiple lab members, while K-series awards are individual career development grants that may not fund additional positions. Understanding these distinctions helps you interpret search results accurately.

Look beyond the dollar amount. A $500,000 per year R01 at a high-cost institution may support fewer positions than a $300,000 award at a university with lower overhead rates. The project abstract and public health relevance statement reveal whether the PI's research direction aligns with your interests and expertise.

Understanding PI Grant Portfolios

A PI's grant portfolio reveals more than individual awards. Investigators with multiple active grants often run larger labs with more diverse projects, which can mean more opportunities for trainees. However, a PI with a single well-funded grant may offer more focused mentorship and a clearer path to publications.

Multi-PI grants (those with more than one principal investigator listed) indicate collaborative research and may involve trainees from multiple institutions. These can be excellent opportunities for interdisciplinary training but may also mean split attention from any single mentor.

Pay attention to the timing of awards. A PI who just received a new five-year R01 is in a different position than one whose grant ends next year. New awards often correspond to lab expansion and active recruiting, making them ideal targets for job seekers. The start and end dates shown in each result help you assess this timing.

Best Practices for Contacting Funded PIs

Once you identify a promising PI through this tool, the next step is outreach. NIH public records do not include email addresses, but you can usually find contact information through the PI's institutional profile page, lab website, or recent publications. Google Scholar, PubMed, and the PI's department website are reliable starting points.

When reaching out, reference the specific grant that caught your attention. Mentioning the project title and explaining how your skills relate to the funded work shows that you have done your homework. Keep your initial message concise: introduce yourself, explain your interest, attach your CV, and ask whether they anticipate openings.

Timing matters. Contacting a PI within the first year of a new award is ideal, as this is when they are most likely to be recruiting. If you find multiple promising PIs in the same field, prioritize those with the most recent award notices and activity codes that support trainee positions such as R01, U01, or P-series grants.

Frequently Asked Questions About PI Search

What does the opportunity score mean?

The opportunity score is a heuristic that combines award recency, funding amount, activity code type, and project characteristics to estimate how actionable a result might be for job seekers or collaborators. Higher scores suggest stronger signals, but always verify by reading the abstract and checking the PI's current lab page.

Why can't I find a PI I know has funding?

Name variations are the most common cause. Try searching with just the last name, or use different formats like "Smith, John" versus "John Smith." Some PIs also publish under different name variations or may have awards under a previous institutional affiliation.

Does this tool show all NIH-funded PIs?

The tool searches NIH RePORTER data for the keyword and year range you specify. It returns PIs whose funded projects match your search terms. PIs with grants in unrelated areas or whose projects use different terminology will not appear in keyword-filtered results.

What is the difference between "Likely hiring" and "Training-friendly" filters?

"Likely hiring" flags PIs with large new awards or activity codes typically associated with lab expansion. "Training-friendly" identifies awards that include training components or are at institutions known for postdoctoral programs. Both are heuristic filters to help prioritize your outreach.

How to use this well

Start broad, then narrow. Search a field first, then refine by timeframe once you understand who is currently active.

After you find a promising PI, cross-check them in Check PI Funding and review their institution, mechanism type, and project abstracts before reaching out.

What a match means

A result means the keyword appears relevant to the funded project data we searched. It does not guarantee the PI is hiring or that the grant is still active.

Use the abstract, award year, mechanism, and organization context to decide whether the record is strategically relevant.

Data limits

NIH records can lag, institutional names can vary, and some investigators publish or file awards under multiple name formats.

For details on source coverage and refresh cadence, read Data & Methodology.

Related guides

Companion guides for turning a PI search result into useful outreach or a job lead.

Career Guide8 min read

How Postdocs Can Find PIs with New NIH Funding

A tactical job-search guide for identifying recently funded labs, judging fit, and timing outreach to principal investigators.

Read guide
Career Guide7 min read

How to Contact a PI: Finding Emails and Crafting the Perfect Message

Emailing strategies, outreach examples, and a workflow for turning NIH funding signals into focused PI conversations.

Read guide
Career Guide10 min read

How to Read a New NIH Award Like a Hiring Signal

A practical framework for using newly funded NIH awards to judge whether a lab may be expanding, hiring, or worth contacting now.

Read guide
Funding Strategy16 min read

How to Find NIH Funding Opportunities: A Step-by-Step Guide for Researchers

Learn how to find NIH funding opportunities using the NIH Guide, Grants.gov, FOAs, NIH RePORTER, and program officer outreach.

Read guide

Recently Funded Labs in Trending Areas

Principal investigators who received NIH awards in the last 90 days, organized by research area. Use this as a starting point for postdoc searches, collaborator outreach, or competitor scans. Counts and labs refresh daily.

Alzheimer's disease

Neurodegeneration, biomarkers, and disease-modifying therapies.

  • Carlos Cruchaga — WASHINGTON UNIVERSITY, MO
    CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"
    $101,153 · awarded Feb 25, 2026 · 3U01AG084514-01A1S1
  • Carlos Cruchaga — WASHINGTON UNIVERSITY, MO
    CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"
    $3,086,339 · awarded Feb 19, 2026 · 1U01AG084514-01A1
  • HARALD SONTHEIMER — UNIVERSITY OF VIRGINIA, VA
    Extracellular matrix and memory impairments in Alzheimer disease
    $709,066 · awarded Apr 7, 2026 · 5R01AG085359-03
  • Keith Josephs — MAYO CLINIC ROCHESTER, MN
    The neurobiology of two distinct subtypes of neurodegenerative apraxia of speech: phenotypes of Alzheimer disease related 4-repeat tauopathies
    $643,670 · awarded Apr 1, 2026 · 5R01DC014942-09
  • DMITRIY YABLONSKIY — WASHINGTON UNIVERSITY, MO
    Deep-Learning-Augmented Quantitative Gradient Recalled Echo (DLA-qGRE) MRI for in vivo Clinical Evaluation of Brain Microstructural Neurodegeneration in Alzheimer Disease
    $661,985 · awarded Mar 3, 2026 · 4R01AG082030-02
Search more PIs in Alzheimer's disease →

CRISPR & gene editing

Therapeutic gene editing, base editing, and prime editing.

  • Changchun Liu — UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT
    Asymmetric CRISPR Approach for Nucleic Acid Quantification
    $643,849 · awarded Mar 30, 2026 · 2R01EB023607-06A1
  • William Pu — BOSTON CHILDREN'S HOSPITAL, MA
    A modular system for murine CRISPR genome and epigenome editing
    $267,000 · awarded Mar 27, 2026 · 5R21OD037909-02
  • Naama Aviram — SLOAN-KETTERING INST CAN RESEARCH, NY
    Molecular mechanisms of memory formation and tolerance in CRISPR-Cas systems
    $249,000 · awarded Apr 2, 2026 · 5R00GM148720-04
  • Mats Ljungman — UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
    Precision targeting of bladder cancer using CRISPR
    $582,849 · awarded Feb 17, 2026 · 5R01CA285730-03
  • Shannon Miller — SCRIPPS RESEARCH INSTITUTE, THE, CA
    Development of potent and safe CRISPR tools for in vivo gene editing using directed evolution
    $230,000 · awarded May 5, 2026 · 5R21EB036298-03
Search more PIs in CRISPR & gene editing →

Cancer immunotherapy

Checkpoint inhibitors, CAR-T, TIL therapy, and beyond.

  • TERRY SHEPPARD — KEYSTONE SYMPOSIA, CO
    Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations
    $5,000 · awarded Mar 3, 2026 · 1R13CA310704-01
  • Veronika Fedirko — UNIVERSITY OF TX MD ANDERSON CAN CTR, TX
    Gut Microbiome and Cancer Immunotherapy Outcomes in Advanced Renal Cell Carcinoma
    $927,329 · awarded Mar 3, 2026 · 5R01CA255322-05
  • Yuwen Zhu — UNIVERSITY OF COLORADO DENVER, CO
    The GPR171 pathway in cancer immunotherapy
    $355,706 · awarded Apr 2, 2026 · 5R01CA279398-04
  • ANDREW WIEMER — UNIVERSITY OF CONNECTICUT STORRS, CT
    Synthesis and evaluation of BTN3A1 ligands for cancer immunotherapy
    $374,171 · awarded May 1, 2026 · 5R01CA266138-05
  • Wei Hu — YALE UNIVERSITY, CT
    Novel Treg inactivating approach for cancer immunotherapy via targeted protein degradation
    $482,312 · awarded Apr 6, 2026 · 1R01CA295942-01A1
Search more PIs in Cancer immunotherapy →

GLP-1 & metabolic disease

Diabetes, obesity, and weight-loss therapeutic mechanisms.

  • ZHIPING PANG — RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ
    Synaptic and circuit mechanisms of central GLP-1 signaling in energy balance
    $479,051 · awarded Apr 23, 2026 · 5R01DK131452-05
  • Madhusmita Misra — UNIVERSITY OF VIRGINIA, VA
    Bone metabolism in adolescents undergoing GLP-1 receptor agonist therapy
    $471,776 · awarded Apr 24, 2026 · 5R01HD118635-07
  • STEVEN SCHWENDEMAN — UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
    Remote Loading of Melanocortin and GLP-1 Peptides in Polymers for Treatment of Obesity
    $231,000 · awarded Apr 17, 2026 · 1R56DK141545-01A1
  • Jessica Barson — DREXEL UNIVERSITY, PA
    Suppression of ethanol dependence-induced maladaptive appetitive and consummatory behavior by the GLP-1 system
    $564,306 · awarded May 5, 2026 · 1R01AA031732-01A1
  • MICHAEL CAMILLERI — MAYO CLINIC ROCHESTER, MN
    A Randomized, placebo-controlled trial of the effects of Long-Acting GLP-1 or Dual Incretin (GLP-1 and GIP) Modulation on Gastrointestinal Functions and Relationship to Weight Loss
    $322,800 · awarded Apr 9, 2026 · 5R01DK142606-02
Search more PIs in GLP-1 & metabolic disease →

Long COVID

Post-acute sequelae and chronic infection-driven illness.

  • Alexei Tumanov — UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX
    Lymphotoxin-dependent control of long COVID
    $234,715 · awarded Feb 13, 2026 · 1R21AI185790-01A1
  • Amal Amer — OHIO STATE UNIVERSITY, OH
    Role of the Non-canonical Inflammasome in SARS-CoV-2-mediated Pathology and Coagulopathy
    $2,974,582 · awarded Apr 21, 2026 · 5P01AI175399-03
  • Alba Azola — JOHNS HOPKINS UNIVERSITY, MD
    Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 onset ME/CFS versus Pre-Pandemic ME/CFS Patients
    $633,378 · awarded Apr 17, 2026 · 1R01NS147100-01
  • DANIELLE REED — MONELL CHEMICAL SENSES CENTER, PA
    Inflammation and chemosensory loss
    $2,654,249 · awarded Feb 26, 2026 · 1P50DC022549-01A1
  • Jarred Younger — UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL
    Low-dose naltrexone (LDN) for the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
    $556,686 · awarded Mar 6, 2026 · 1UG3NS141843-01A1
Search more PIs in Long COVID →