NIH R34 Grants — Planning Grant
Reviewed by Dr. Meng ZhaoLast reviewed June 9, 2026Data refreshed September 5, 2026Editorial standards
Planning for clinical trials or large-scale studies
Funding
Up to $450,000 direct costs over the project
Duration
Up to 3 years
Eligibility
Investigators planning trials
Activity code
R34
What is the NIH R34 grant?
The R34 is the NIH Planning Grant — used to support the planning phase of a clinical trial or other large research effort, ahead of a full implementation grant (e.g., U01, R01).
Recent R34 awards from NIH RePORTER
Examples of funded R34 projects across the last two fiscal years. The matching-award count comes from the full result set; funding totals, averages, rankings, and examples use the first 500 records returned by NIH RePORTER. Figures reflect a snapshot last refreshed on September 5, 2026.
Example R34 projects from the sample
Establishing a Ground Truth for Inter-Areal Neuronal Communication
5R34NS143713-02Alexander Huk · UNIVERSITY OF CALIFORNIA LOS ANGELES, CA · $324,765 · awarded Aug 27, 2026 · NIHPROJECT SUMMARY/ABSTRACT This proposal focuses on the development of a powerful neural recording approach that leverages recent technical and conceptual innovations in neuroscience— and could take them to the next level for answering how neurons perform “computations” upon their inputs. Specifically, we propose to develop techniques for performing dual in…
Addressing mental health and HIV medication adherence among high-risk men in a resource-limited setting
5R34MH135806-03DON OPERARIO · EMORY UNIVERSITY, GA · $72,449 · awarded Aug 27, 2026 · NIHThis R34 application, submitted under PAR-23-060 (“Formative and Pilot Intervention Research to Optimize HIV Prevention and Care Continuum Outcomes”), proposes to develop and pilot test WeCare—a novel, integrated intervention addressing the dual and interconnected challenges of mental health and HIV medication adherence among high-risk men in…
Implementation and pilot testing of a culturally centered CBT protocol for suicidal behaviors among youth
5R34MH136224-03Yovanska DuarteVelez · EMMA PENDLETON BRADLEY HOSPITAL, RI · $112,004 · awarded Aug 26, 2026 · NIHSuicide attempts and suicide-related morbidity among Hispanic adolescents remain a significant and measurable mental health disparity in the United States. Hispanic/Latino youth experience elevated risk for suicidal ideation and suicide attempts, yet there remains a critical need for replicated, culturally responsive, suicide-specific interventions that can…
Antihypertensive self-titration to improve US blood pressure control
5R34HL178960-02Nancy Haff · BRIGHAM AND WOMEN'S HOSPITAL, MA · $263,576 · awarded Aug 26, 2026 · NIHNearly 1 in 2 US adults has hypertension, and it is a leading cause of myocardial infarction, stroke, and death. Despite the importance of hypertension and the widespread availability of medication treatment, less than half of patients have blood pressures that are controlled. This is in part due to the way in which we deliver care, and new strategies are…
Innovations for peer-delivered and family-engaged brief interventions for youth suicide in Nepal: A pilot hybrid type 2 implementation study
3R34MH136250-03S2Ashley Hagaman · YALE UNIVERSITY, CT · $11,904 · awarded Aug 25, 2026 · NIHOur proposal aims to co-design and pilot test the implementation of a package of brief, theory-driven interventions for suicide prevention among youth (12–24 years) delivered by peers (YPF-SuPP). YPF-SuPP integrates two evidence-based interventions tested in South Asia (safety planning and contact follow-up) with two core innovations: safety plans delivered…
AI-Enhanced App-based Intervention for Adolescent E-cigarette Cessation
5R34CA287720-03Eunhee Park · STATE UNIVERSITY OF NEW YORK AT BUFFALO, NY · $243,403 · awarded Aug 25, 2026 · NIHProject Summary Abstract Electronic cigarette (e-cigarette) use among adolescents is an emerging public health problem. In 2020, 19.5% of high school students and 4.7% of middle school students used e-cigarettes, even though e-cigarette use is known to be harmful to adolescent health, resulting in nicotine-related symptoms of addiction and various other…
Developing measures to improve access to integrated mental health care services in under-resourced settings
5R34MH137223-03Maria Prom de Illanes · BOSTON MEDICAL CENTER, MA · $179,308 · awarded Aug 25, 2026 · NIHMental disorders are a leading cause of morbidity and mortality, and yet there are significant gaps in accessing mental health care in under-resourced settings. It is necessary to demonstrate acceptance, feasibility, and efficacy of mental health care systems interventions prior to larger scale-up where resources are limited, as well as ongoing measurement…
Optimizing implementation strategies for guideline-concordant hypertensive disorders of pregnancy care in community clinics
1R34HL186380-01Bridgette Blebu · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER, CA · $161,500 · awarded Aug 24, 2026 · NIHABSTRACT Background: Hypertensive disorders of pregnancy (HDP), including preeclampsia, occur in 10% of pregnancies in the U.S. and contribute to maternal deaths. Preeclampsia is linked to long-term cardiovascular risk, making prevention a clinical and public health priority. Daily low-dose aspirin (LDA, 81 mg daily) in pregnancy is an effective,…
Adapting a novel mental health prevention intervention for in-transit mothers with young children
3R34MH134047-01S1Shira Goldenberg · SAN DIEGO STATE UNIVERSITY, CA · $224,318 · awarded Aug 24, 2026 · NIHThe goal of this pilot study is to adapt and pilot-test a novel mental health prevention intervention for in-transit mothers with young children (MMC). Population mobility is rising at record-high rates, with the number of women traveling with children continuing to rise. The city of Tijuana, Mexico is located at the busiest land crossing globally and faces…
EPIC-LT: Eliminating PGD through Inhibition of CCR5 in Lung Transplantation
5R34HL177405-02Daniel Calabrese · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA · $246,725 · awarded Aug 21, 2026 · NIHProject Summary Lung transplant recipient survival lags other solid organ recipients, with the main early causes of death being primary graft dysfunction (PGD). PGD occurs in up to 1/3 of all recipients, is driven by the innate immune response, and has no known medical therapies for treatment or prevention. Our group has recently shown that Natural Killer…
Planning grant to evaluate the use of pentavalent meningococcal vaccine in pregnant women in sub-Saharan Africa
1R34AI195140-01Wilbur Chen · UNIVERSITY OF MARYLAND BALTIMORE, MD · $233,250 · awarded Aug 20, 2026 · NIHProject Summary/Abstract Meningococcal disease in sub-Saharan Africa is an annually recurring and devastating public health problem. Building upon what has been observed to be the near elimination of serogroup A disease with the development and implementation of a monovalent meningococcal vaccine, MenAfriVac, a pentavalent meningococcal vaccine was…
Innovations for peer-delivered and family-engaged brief interventions for youth suicide in Nepal: A pilot hybrid type 2 implementation study
3R34MH136250-03S1Ashley Hagaman · YALE UNIVERSITY, CT · $37,495 · awarded Aug 20, 2026 · NIHOur proposal aims to co-design and pilot test the implementation of a package of brief, theory-driven interventions for suicide prevention among youth (12–24 years) delivered by peers (YPF-SuPP). YPF-SuPP integrates two evidence-based interventions tested in South Asia (safety planning and contact follow-up) with two core innovations: safety plans delivered…
Funding institutes in the sample
| Institute | Awards | Funding |
|---|---|---|
| NIH | 487 | $140.1M |
Most frequent institutions in the sample
- YALE UNIVERSITY — 21 awards
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — 19 awards
- DUKE UNIVERSITY — 17 awards
- MASSACHUSETTS GENERAL HOSPITAL — 15 awards
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — 13 awards
- UNIVERSITY OF WASHINGTON — 11 awards
- UNIV OF NORTH CAROLINA CHAPEL HILL — 10 awards
- BROWN UNIVERSITY — 10 awards
Source: NIH RePORTER. Verify any award in the official record by searching its project number. See our data methodology for how this sample is built and its limitations.
Decision guide
Choose R34 when
Choose R34 when you need 1–3 years to plan a multi-site or otherwise complex clinical trial.
Choose another mechanism when
R34 is not for executing trials, only for planning them.
Who applies for R34
Investigators planning a clinical trial that will be too large for direct R01 submission, or that requires upfront infrastructure design (data coordination, IRB harmonization, recruitment planning).
Compare nearby NIH grant mechanisms
Searchers often land on R34 while deciding between adjacent NIH activity codes. Compare scope, NIH staff involvement, budget scale, and applicant stage before choosing a funding opportunity.
Discrete, specified investigator-led research project
Investigator-led research with NIH staff substantial involvement
For broad grant lookup, use the NIH grant search to find funded examples by activity code, PI, institution, and award year.
Search tips for R34
- R34 awards often immediately precede a U01 or R01 trial implementation grant from the same PI.
Open NIH NOFOs for R34
NIH accepts R34 applications only through a notice of funding opportunity (NOFO). These 13 are open or opening soon; each page lists due dates, participating institutes, related notices, and the projects NIH funded under it.
- PAR-28-093NIDA · next due Feb 16, 2027Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials (R34 Clinical Trial Optional)
- PAR-25-358NEI · next due Feb 16, 2027NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed)
- PAR-24-329NIDA · next due Feb 16, 2027Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)
- PAR-25-284NIMH · next due Feb 16, 2027Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
- PAR-25-032NHLBI · next due Feb 16, 2027NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)
- PAR-25-100NIDA · next due Feb 16, 2027Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)
- PAR-25-288NIMH · next due Feb 16, 2027Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)
- PA-25-093NIAMS · next due Feb 16, 2027Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed)