David Alan Kass

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

High-opportunity lead · 80/100

Likely hiring

Large award

Very recent

Active award

$1,089,224

FY 2026

Project Title

Intersection of Obesity and Heart Failure with Preserved Ejection Fraction

Grant Number:

5R35HL166565-04

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/20/2023

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

This project will elucidate the biological mechanisms by which obesity alters the myocardium in patients with heart failure and a preserved ejection fraction (HFpEF) to ultimately derive sorely needed precision- guided therapies. HFpEF currently represents more than half of all heart failure worldwi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael W Schwartz

UNIVERSITY OF WASHINGTON, SEATTLE, WA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$888,773

FY 2026

Project Title

Defining the contributions of hypothalamic microglia and perineuronal nets to obesity pathogenesis

Grant Number:

1R01DK140210-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary An emerging model of obesity pathogenesis posits a central role for the inflammatory activation of hypothalamic microglia localized to the arcuate nucleus (ARC, a key brain area for the control of food intake and body weight) in the pathogenesis of diet-induced obesity (DIO), a findi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOSHUA P THALER

UNIVERSITY OF WASHINGTON, SEATTLE, WA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$888,773

FY 2026

Project Title

Defining the contributions of hypothalamic microglia and perineuronal nets to obesity pathogenesis

Grant Number:

1R01DK140210-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary An emerging model of obesity pathogenesis posits a central role for the inflammatory activation of hypothalamic microglia localized to the arcuate nucleus (ARC, a key brain area for the control of food intake and body weight) in the pathogenesis of diet-induced obesity (DIO), a findi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jeanie Beatrice Tryggestad

UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OKLAHOMA CITY, OK

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$825,450

FY 2026

Project Title

Identifying Metabolic and Psychosocial Antecedents and Characteristics of youth-onset Type 2 diabetes (IMPACT DM)

Grant Number:

5U01DK135007-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/23/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><9 year old><9 years of age><Abdominal obesity><Active Follow-up><Address><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Aeroseb-HC><Affect><Age><Algorithms><Android fat distribution><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Biometrics><Biometry><Biostatistics><Blood Pressure><Blood Serum><Body Composition><Body mass index><C-Peptide><Catchment Area><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Center for Translational Science Activities><Central obesity><Centripetal obesity><Cetacort><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Children's Hospital><Chronic stress><Clinic><Clinical><Collaborations><Colorado><Complications of Diabetes Mellitus><Consensus><Continuous Glucose Monitor><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Coupled><D-Glucose><D-Isoglucosamine><Dermacort><Development><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diagnosis><Diet><Disease><Disease Progression><Disorder><Dysfunction><Early identification><Eldecort><Endocrine Gland Secretion><Energy Expenditure><Energy Metabolism><Enrollment><Environment><Epidemiology><Ethnic Origin><Ethnicity><Event><Exposure to><Failure><Family><Family Medical History><Family Medical History Epidemiology><Family history of><Fats><Fatty acid glycerol esters><Feedback><Free Fatty Acids><Fructosamine><Functional disorder><Funding><Future><GI microbiome><Genetic Materials><Geography><Gestation><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><HDL Cholesterol><HDL Cholesterol Lipoproteins><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Hemoglobin A(1)><High Density Lipoprotein Cholesterol><Hispanic><Hispanic Americans><History><Hormones><Hour><Humulin R><Hydrocortisone><Hydrocortone><Hypertension><Hytone><IRB><IRBs><Infrastructure><Institutional Review Boards><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Latino><Leadership><Life Style><Lifestyle><Maturity-Onset Diabetes Mellitus><Measurable><Measures><Mediating><Medical><Medical History><Medicine><Mental Depression><Metabolic><MicroRNAs><Microvascular Dysfunction><Modeling><NIDDK><NIDDM><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Native American group><Native American individual><Native American people><Native American population><Native Americans><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nutracort><OGTT><Obesity><Obesity Epidemic><Oklahoma><Onset of illness><Oral Glucose Tolerance Test><Overweight><Pancreas><Pancreatic><Participant><Patient Recruitments><Pattern><Pediatric Hospitals><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Position><Positioning Attribute><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Value><Pregnancy><Prevalence><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Proctocort><Proinsulin><Proteins><Protocol><Protocols documentation><Provider><Psychosocial Factor><Psychosocial Stress><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Recording of previous events><Records><Regression Analyses><Regression Analysis><Regression Diagnostics><Regular Insulin><Reporting><Research><Research Personnel><Researchers><Rest><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Salivary><Sampling><Serum><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Statistical Regression><Stress><Subcellular Process><T2 DM><T2D><T2DM><Testing><Therapeutic Hormone><Time><Translational Research><Translational Science><Truncal obesity><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Universities><Urban Population><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Visit><Youth><Youth 10-21><active followup><adipocytokines><adipokines><adiposity><adolescent minority><adult onset diabetes><adverse childhood events><adverse childhood experiences><age 9><age 9 years><ages><alpha-Lipoprotein Cholesterol><at risk behavior><bio-markers><biobank><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><boys><cardiometabolic><cardiometabolism><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical translation><clinically translatable><cohort><computer based prediction><connecting peptide><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><cytokine><demographics><depression><deprivation><design><designing><developmental><diabetes><diabetes risk><diets><digestive tract microbiome><disease onset><disorder onset><effective therapy><effective treatment><enroll><enteric microbiome><epidemiologic><epidemiological><exercise capacity><experience><exposed in utero><fasting glucose><fetal exposure><follow up><follow-up><followed up><followup><gastrointestinal microbiome><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><gut microbiome><gut-associated microbiome><hemoglobin A1c><high blood pressure><high risk><histories><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><impaired glucose tolerance><improved><in utero><in utero exposure><indexing><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><intra-uterine environmental exposure><intrauterine environmental exposure><juvenile><juvenile human><ketosis resistant diabetes><kids><malleable risk><maternal adiposity><maternal obesity><maturity onset diabetes><miRNA><microvascular complications><microvascular disease><minority children><minority youth><modifiable risk><new marker><nine year old><nine years of age><novel><novel biomarker><novel marker><obese children><obesity during childhood><obesity in children><obesity intervention><obesity therapy><obesity treatment><participant recruitment><pathophysiology><patient population><patient retention><pediatric><pediatric minority><pediatric obesity><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><predictive modeling><prenatal exposure><prenatally exposed><preservation><prevent><preventing><primary care practice><primary end point><primary endpoint><programs><progression risk><psychologic><psychological><psychosocial><psychosocial stresses><psychosocial stressors><psychosocial variables><public health relevance><racial minority><recruit><rural patients><safety net><screening><screenings><secondary end point><secondary endpoint><social><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><specimen bank><specimen repository><success><therapeutic target><therapy optimization><timeline><translation research><translational investigation><translational research center><translational sciences center><treatment optimization><treatment program><treatment strategy><type 2 DM><type II DM><type two diabetes><urban group><urban individual><urban people><visceral obesity><young minority><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MICHAEL D. JENSEN

MAYO CLINIC ROCHESTER, ROCHESTER, MN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$758,143

FY 2026

Project Title

Regional Fatty Acid Metabolism In Humans

Grant Number:

5R01DK045343-33

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/1992

End Date:

3/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Our goal is to understand the why obesity, and specifically upper body/visceral obesity (UBO), causes insulin resistance, Type 2 Diabetes and the other health problems. We study what regulates the storage of fat in adipose tissue and release of free fatty acids (FFA) from a...

Research Terms

<21+ years old><Abdomen><Abdominal obesity><Adipocytes><Adipose Cell><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Android fat distribution><Area><Biological><Biology><Blood><Blood Circulation><Blood Pressure><Blood Reticuloendothelial System><Blood Serum><Bloodstream><Body Tissues><Body Weight decreased><Body fat><Causality><Central obesity><Centripetal obesity><Characteristics><Data><Diabetes Mellitus><Diet><Dietary Fats><Disease><Disorder><Enzyme Gene><Enzymes><Equilibrium><Etiology><Fat Cells><Fats><Fatty Acid Metabolism Pathway><Fatty Acids><Fatty Tissue><Fatty acid glycerol esters><Female><Female Health><Free Fatty Acids><Future><Gene Action Regulation><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Goals><Gonadal Steroid Hormones><Grant><Health><Health Benefit><Heterogeneity><Human><Individual><Individual Differences><Inflammation><Insulin Resistance><Intervention><Ketosis-Resistant Diabetes Mellitus><Leg><Life Style><Lifestyle><Lifestyle Therapy><Link><Lipids><Lipocytes><Lipolysis><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Measures><Menopause><Metabolic><Modern Man><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Outcome><Persons><Phenotype><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Pre-Menopause><Pre-menopausal Period><Premenopausal><Premenopausal Period><Premenopause><Publications><Regulation><Rest><Risk><Scientific Publication><Serum><Sex Hormones><Sex Steroid Hormones><Skin><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Techniques><Therapeutic><Tissues><Truncal obesity><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><Visceral fat><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Woman><Women's Health><abdominal adiposity><abdominal fat><adipose><adiposity><adult adiposity><adult obesity><adult onset diabetes><adulthood><adults with obesity><after menopause><balance><balance function><biologic><body weight gain><body weight increase><body weight loss><causation><corpulence><diabetes><dietary lipid><dietary restriction><diets><differences in health><disease causation><energy balance><excessive weight gain><experiment><experimental research><experimental study><experiments><extreme weight gain><fatty acid metabolism><following menopause><gonadal steroids><health difference><improved><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><men><novel><past menopause><post-menopausal><postmenopausal><postmenopausal status><pre-menopausal><premenopausal status><response><restricted diet><serious weight gain><severe weight gain><sex steroid><subcutaneous><subdermal><sugar><type 2 DM><type II DM><type two diabetes><visceral obesity><weight loss intervention><weight loss program><weight loss programming><weight loss therapy><weight loss treatment><weights><white adipose tissue><wt gain><wt-loss><yellow adipose tissue><♀>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ASHLESHA DATAR

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$756,550

FY 2026

Project Title

The Impact of Improvements in Built and Social Environments and Housing on Obesity in Public Housing Residents: Evidence from a Natural Experiment

Grant Number:

2R01CA228058-06A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2018

End Date:

3/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Obesity continues to increase in disadvantaged populations. Neighborhood revitalization efforts in low- income communities have sought to reverse these trends. One such effort is currently underway in Watts, Los Angeles, where the Jordan Downs (JD) public housing site, an obsolete project ...

Research Terms

<21+ years old><Abdominal obesity><Active Follow-up><Address><Adult><Adult Human><Android fat distribution><Area><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Bicycling><Biological Markers><Black><Black race><Blood Glucose><Blood Sugar><Body Weight decreased><Body mass index><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Central obesity><Centripetal obesity><Cohort Studies><Communities><Data><Data Collection><Development><Disparity population><Dose><Economic Income><Economical Income><Elements><Environment><Exercise><Exposure to><Funding><Green space><Habits><Health><Healthy Eating><Heterogeneity><Hispanic><Household><Housing><Income><Intake><Interdisciplinary Research><Interdisciplinary Study><Jordan><Light><Los Angeles><Low income><Methods><Multidisciplinary Collaboration><Multidisciplinary Research><Natural experiment><Neighborhoods><Obesity><Outcome><Overweight><Parents><Pathway interactions><Perception><Phase><Photoradiation><Physical activity><Population Research><Population-based research><Population-level research><Prevalence><Public Health><Public Housing><Quasi-experiment><Quasi-experimental analysis><Quasi-experimental approach><Quasi-experimental design><Quasi-experimental methods><Quasi-experimental research><Quasi-experimental study><Quasi-experimental technique><Quetelet index><Reporting><Risk Factors><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Site><Sleep><Social Environment><Stress><Subgroup><Supermarket><Survey Instrument><Surveys><Testing><Time><Truncal obesity><Typology><Variant><Variation><Weight Loss><Weight Reduction><active followup><adiposity><adulthood><behavior change><bio-markers><biologic marker><biomarker><body weight loss><building design><built environment><cohort><cohort investigation><cohort research><cohort research study><cohort survey><community center><community centers><community intervention><community level intervention><community partnership><community-based intervention><comparator group><comparison group><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><corpulence><design><designing><developmental><dietary><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><experience><follow up><follow-up><followed up><followup><greenspace><group disparity><group inequality><group inequity><high risk group><high risk individual><high risk people><high risk population><improved><incomes><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><insight><investigate cohort><investigate population><minority communities><novel><pandemic effect><pandemic impact><pandemic outcome><pandemic repercussions><parent><parent grant><pathway><population inequality><population inequity><population investigation><population level investigation><population specific research><prevent><preventing><public health priorities><recruit><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social><social climate><social context><social health determinants><social space><socio-economic><socio-economically><socioeconomically><socioeconomics><socioenvironment><socioenvironmental><stress reduction><studies of populations><study cohort><study of the population><study population><subgroup disparity><sugar><survey cohort><survey population><trend><unequal group><unequal population><visceral obesity><walkability><walkable><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jonathan E Posner

DUKE UNIVERSITY, DURHAM, NC

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$741,700

FY 2026

Project Title

Prenatal maternal obesity and neurodevelopment: The mediating role of the microbiome and metabolome

Grant Number:

5R01MH133313-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Impaired emotion regulation (ER) is a risk factor for a wide range of neuropsychiatric conditions and safeguarding its development could have important implications on mental health. Pre-pregnancy obesity has long been associated with indicators of impaired ER in children – e.g., ele...

Research Terms

<0-11 years old><12 year old><12 years of age><1st trimester><3rd trimester><5-HT><5-Hydroxytryptamine><5HT><AD/HD><ADHD><Address><Affect><Ammon Horn><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Anxiety Disorders><Attention deficit hyperactivity disorder><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Behavioral Assay><Birth><Blood><Blood Reticuloendothelial System><Body mass index><Brain><Brain Nervous System><Central Lobe><Child><Child Nutrition><Child Rearing><Child Youth><Children (0-21)><Clinical><Code><Coding System><Collection><Cornu Ammonis><Cross-Product Ratio><Data><Depressive Syndromes><Depressive disorder><Development><Diffusion><Discipline of obstetrics><Dopamine><Early Placental Phase><Eating Disorders><Emotional><Encephalon><Enrollment><Enteramine><Enzyme Gene><Enzymes><Exposure to><Feces><First Pregnancy Trimester><First Trimester><Functional MRI><Functional Magnetic Resonance Imaging><GI microbiome><Genes><Genetic><Gestation><Health><Hippocampus><Hippophaine><Human><Hydroxytyramine><Impairment><Individual><Individuals from minority><Individuals of minority><Infant><Inflammation><Insula><Insula of Reil><Intermediary Metabolism><Island of Reil><L-Tryptophan><Laboratories><Last Trimester><Levotryptophan><Life><Link><Low income><MR Imaging><MR Tomography><MRI><MRI Scans><MRIs><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Measures><Mediating><Mediation><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical Records><Mental Depression><Mental Health><Mental Hygiene><Mental disorders><Mental health disorders><Metabolic><Metabolic Pathway><Metabolic Processes><Metabolism><Minority Groups><Minority People><Minority Population><Minority individual><Modern Man><Mothers><NMR Imaging><NMR Tomography><Negotiating><Negotiation><Neural Development><Nuclear Magnetic Resonance Imaging><Obesity><Obstetrics><Odds Ratio><Parenting><Parenting behavior><Parturition><Pathway interactions><Perinatal><Peripartum><Position><Positioning Attribute><Predominantly Hyperactive-Impulsive Type Attention-Deficit Disorder><Predominantly Hyperactive-Impulsive Type Hyperactivity Disorder><Prefrontal Cortex><Pregnancy><Pregnancy Trimesters><Pregnant Women><Prevention><Psychiatric Disease><Psychiatric Disorder><Psychological Health><Psychopathology><Quetelet index><Relative Odds><Research><Rest><Risk><Risk Factors><Risk Ratio><Rodent Model><Role><Sampling><Serotonin><System><Temperament><Testing><Third Pregnancy Trimester><Third Trimester><Time><Tryptophan><Tryptophan Metabolism><Tryptophan Metabolism Pathway><Tyrosine><Tyrosine Metabolism><Tyrosine Metabolism Pathway><Universities><Vertical Transmission><Zeugmatography><abnormal psychology><adiposity><age 12><age 12 years><amygdaloid nuclear complex><birth cohort study><birth cohort survey><brain MR imaging><brain MRI><brain magnetic resonance imaging><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><childrearing><cohort><comparing females and males><comparing women and men><corpulence><depression><design><designing><developmental><diffused><diffuses><diffusing><diffusions><digestive tract microbiome><emotion regulation><emotional regulation><enroll><enteric microbiome><epidemiology research study><epidemiology study><epidemiology survey><expectant mother><expectant women><expecting mother><expecting women><experience><fMRI><females compared to males><females compared with males><females versus males><females vs. males><fetal><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><high risk group><high risk individual><high risk people><high risk population><hippocampal><in utero><individuals who are pregnant><innovate><innovation><innovative><intestinal biome><intestinal microbiome><kids><longitudinal design><longitudinal experimental design><longitudinal research design><longitudinal study design><maternal GI tract><maternal adiposity><maternal gut><maternal microbiome><maternal obesity><maternal serum><maternal stress><mental illness><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><metagenome><microbial><microbiome><mood symptom><mother's gut><mouse model><multi-modality><multimodality><murine model><neural imaging><neuro-imaging><neurodevelopment><neuroimaging><neurological imaging><neuropsychiatric><neuropsychiatry><offspring><pathway><pediatric nutrition><people who are pregnant><postnatal><pre-clinical><pre-clinical research><preclinical><preclinical research><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prepregnancy><prepregnancy obesity><psychiatric illness><psychological disorder><sex><social role><stool><stressed mothers><those who are pregnant><tractography><twelve year old><twelve years of age><unborn><women compared to men><women compared with men><women versus men><women vs. men><women who are pregnant><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

YUN WANG

DUKE UNIVERSITY, DURHAM, NC

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$741,700

FY 2026

Project Title

Prenatal maternal obesity and neurodevelopment: The mediating role of the microbiome and metabolome

Grant Number:

5R01MH133313-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Impaired emotion regulation (ER) is a risk factor for a wide range of neuropsychiatric conditions and safeguarding its development could have important implications on mental health. Pre-pregnancy obesity has long been associated with indicators of impaired ER in children – e.g., ele...

Research Terms

<0-11 years old><12 year old><12 years of age><1st trimester><3rd trimester><5-HT><5-Hydroxytryptamine><5HT><AD/HD><ADHD><Address><Affect><Ammon Horn><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Anxiety Disorders><Attention deficit hyperactivity disorder><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Behavioral Assay><Birth><Blood><Blood Reticuloendothelial System><Body mass index><Brain><Brain Nervous System><Central Lobe><Child><Child Nutrition><Child Rearing><Child Youth><Children (0-21)><Clinical><Code><Coding System><Collection><Cornu Ammonis><Cross-Product Ratio><Data><Depressive Syndromes><Depressive disorder><Development><Diffusion><Discipline of obstetrics><Dopamine><Early Placental Phase><Eating Disorders><Emotional><Encephalon><Enrollment><Enteramine><Enzyme Gene><Enzymes><Exposure to><Feces><First Pregnancy Trimester><First Trimester><Functional MRI><Functional Magnetic Resonance Imaging><GI microbiome><Genes><Genetic><Gestation><Health><Hippocampus><Hippophaine><Human><Hydroxytyramine><Impairment><Individual><Individuals from minority><Individuals of minority><Infant><Inflammation><Insula><Insula of Reil><Intermediary Metabolism><Island of Reil><L-Tryptophan><Laboratories><Last Trimester><Levotryptophan><Life><Link><Low income><MR Imaging><MR Tomography><MRI><MRI Scans><MRIs><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Measures><Mediating><Mediation><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical Records><Mental Depression><Mental Health><Mental Hygiene><Mental disorders><Mental health disorders><Metabolic><Metabolic Pathway><Metabolic Processes><Metabolism><Minority Groups><Minority People><Minority Population><Minority individual><Modern Man><Mothers><NMR Imaging><NMR Tomography><Negotiating><Negotiation><Neural Development><Nuclear Magnetic Resonance Imaging><Obesity><Obstetrics><Odds Ratio><Parenting><Parenting behavior><Parturition><Pathway interactions><Perinatal><Peripartum><Position><Positioning Attribute><Predominantly Hyperactive-Impulsive Type Attention-Deficit Disorder><Predominantly Hyperactive-Impulsive Type Hyperactivity Disorder><Prefrontal Cortex><Pregnancy><Pregnancy Trimesters><Pregnant Women><Prevention><Psychiatric Disease><Psychiatric Disorder><Psychological Health><Psychopathology><Quetelet index><Relative Odds><Research><Rest><Risk><Risk Factors><Risk Ratio><Rodent Model><Role><Sampling><Serotonin><System><Temperament><Testing><Third Pregnancy Trimester><Third Trimester><Time><Tryptophan><Tryptophan Metabolism><Tryptophan Metabolism Pathway><Tyrosine><Tyrosine Metabolism><Tyrosine Metabolism Pathway><Universities><Vertical Transmission><Zeugmatography><abnormal psychology><adiposity><age 12><age 12 years><amygdaloid nuclear complex><birth cohort study><birth cohort survey><brain MR imaging><brain MRI><brain magnetic resonance imaging><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><childrearing><cohort><comparing females and males><comparing women and men><corpulence><depression><design><designing><developmental><diffused><diffuses><diffusing><diffusions><digestive tract microbiome><emotion regulation><emotional regulation><enroll><enteric microbiome><epidemiology research study><epidemiology study><epidemiology survey><expectant mother><expectant women><expecting mother><expecting women><experience><fMRI><females compared to males><females compared with males><females versus males><females vs. males><fetal><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><high risk group><high risk individual><high risk people><high risk population><hippocampal><in utero><individuals who are pregnant><innovate><innovation><innovative><intestinal biome><intestinal microbiome><kids><longitudinal design><longitudinal experimental design><longitudinal research design><longitudinal study design><maternal GI tract><maternal adiposity><maternal gut><maternal microbiome><maternal obesity><maternal serum><maternal stress><mental illness><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><metagenome><microbial><microbiome><mood symptom><mother's gut><mouse model><multi-modality><multimodality><murine model><neural imaging><neuro-imaging><neurodevelopment><neuroimaging><neurological imaging><neuropsychiatric><neuropsychiatry><offspring><pathway><pediatric nutrition><people who are pregnant><postnatal><pre-clinical><pre-clinical research><preclinical><preclinical research><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prepregnancy><prepregnancy obesity><psychiatric illness><psychological disorder><sex><social role><stool><stressed mothers><those who are pregnant><tractography><twelve year old><twelve years of age><unborn><women compared to men><women compared with men><women versus men><women vs. men><women who are pregnant><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CHARLES R FLYNN

MIDWESTERN UNIVERSITY, DOWNERS GROVE, IL

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$710,812

FY 2026

Project Title

Intrinsic Primary Afferent Neurons in regulation of intestinal nutrient sensing and obesity

Grant Number:

1R01DK143216-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

1/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Intestinal nutrient sensing is dysregulated in obesity and associated comorbidities including type 2 diabetes (T2D) which feed into the vicious cycle of maladaptive response and nutrient excess. While enteroendocrine mediated nutrient sensing has been studied, the role of gut’s neura...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sinju Sundaresan

MIDWESTERN UNIVERSITY, DOWNERS GROVE, IL

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$710,812

FY 2026

Project Title

Intrinsic Primary Afferent Neurons in regulation of intestinal nutrient sensing and obesity

Grant Number:

1R01DK143216-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

1/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Intestinal nutrient sensing is dysregulated in obesity and associated comorbidities including type 2 diabetes (T2D) which feed into the vicious cycle of maladaptive response and nutrient excess. While enteroendocrine mediated nutrient sensing has been studied, the role of gut’s neura...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amy Christine Arnold

PENNSYLVANIA STATE UNIV HERSHEY MED CTR, HERSHEY, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$706,467

FY 2026

Project Title

Angiotensin-(1-7) and Cardiovascular Derangements in Obesity Hypertension

Grant Number:

5R01HL170140-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Obesity is a global epidemic that is associated with sympathetic overactivation, endothelial dysfunction, and insulin resistance; all of which can contribute to hypertension development. Despite well-established clinical associations, the mechanisms connecting obesity with hypertensi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alfredo Gamboa

PENNSYLVANIA STATE UNIV HERSHEY MED CTR, HERSHEY, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$706,467

FY 2026

Project Title

Angiotensin-(1-7) and Cardiovascular Derangements in Obesity Hypertension

Grant Number:

5R01HL170140-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Obesity is a global epidemic that is associated with sympathetic overactivation, endothelial dysfunction, and insulin resistance; all of which can contribute to hypertension development. Despite well-established clinical associations, the mechanisms connecting obesity with hypertensi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DAVID A FIELDS

JOSLIN DIABETES CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$631,027

FY 2026

Project Title

Maternal exercise during lactation to ignite infant metabolism

Grant Number:

5R01HD117197-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/22/2025

End Date:

3/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Breastfeeding reduces risk of childhood obesity and diabetes, but the mechanisms remain unclear. We recently identified that 12,13-diHOME, a signaling lipid crucial for activating brown adipocyte thermogenesis, is present in human milk. We reported that higher concentration ...

Research Terms

<2-ketoglutarate><2-oxoglutarate><3 Hydroxybutyrate><Acute><Adipocytes><Adipose Cell><Adipose tissue><Affect><Anatomic Sites><Anatomic structures><Anatomy><BMI><BMI percentile><BMI z-score><Blood Plasma><Blood Serum><Body Composition><Body mass index><Breast Epithelial Cells><Breast Feeding><Breast Milk><Breastmilk><Brown Adipose Tissue><Brown Fat><Cell Communication and Signaling><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cell Signaling><Childhood diabetes><Chronic><Clinical Trials><Collection><Consumption><Control Groups><DEXA><DXA><Data><Development><Diet><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Exclusive Breastfeeding><Exercise><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Gene Transcription><Generalized Growth><Genetic Transcription><Goals><Growth><Heat Production><Heel><Hibernating Gland><Human Milk><Human Mother's Milk><Indirect Calorimetry><Infant><Infant Development><Intermediary Metabolism><Intervention><Intracellular Communication and Signaling><Lactation><Life><Link><Linoleic Acids><Lipids><Lipocytes><Mammary Gland Milk><Mature Lipocyte><Mature fat cell><Measures><Mediating><Messenger RNA><Metabolic><Metabolic Processes><Metabolism><Milk><Moderate Exercise><Modification><Monitor><Mother's Milk><Mothers><Nucleotide Metabolism - Reference Pathway><Nucleotide Metabolism Pathway><Nucleotide Sugars Metabolism><Nucleotide Sugars Metabolism Pathway><Nucleotides><Obesity><Outcome><Participant><Pathway interactions><Patient Recruitments><Pilot Projects><Pisum sativum><Plasma><Plasma Serum><Postpartum Period><Proteins><Quetelet index><RNA Expression><Randomized><Regulation><Reporting><Respiration Calorimetry><Rest><Reticuloendothelial System, Serum, Plasma><Risk Reduction><Sampling><Serum><Signal Transduction><Signal Transduction Pathway><Signal Transduction Systems><Signaling><Standardization><Testing><Thermogenesis><Thermographies><Thermography><Time><Tissue Growth><Transcription><Weight><adipogenesis><adipose><adiposity><alpha ketoglutarate><beta-Hydroxybutyrate><biological signal transduction><cell sorting><child adiposity><child obesity><childhood adiposity><childhood obesity><compare intervention><comparison intervention><corpulence><developmental><diabetes during childhood><diabetes in childhood><diabetes in children><diets><exercise intervention><experiment><experimental research><experimental study><experiments><fat metabolism><feeding><glucose metabolism><high BMI><high body mass index><lactating><lactational><lipid biosynthesis><lipid metabolism><lipidome><lipidomics><lipogenesis><mRNA><mammary epithelial cells><mammary gland epithelial cells><maternal adiposity><maternal milk><maternal obesity><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><moderate physical activity><obese children><obesity during childhood><obesity in children><obesity risk><ontogeny><participant recruitment><pathway><pea><pediatric diabetes><pediatric obesity><physical activity intervention><pilot study><post-partum><programs><protective effect><randomisation><randomization><randomly assigned><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><standard of care><sugar nucleotide><thermographic imaging><weights><white adipose tissue><yellow adipose tissue><α-ketoglutarate><α-oxoglutarate><αKG><β-Hydroxybutyrate>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Elvira Marie Isganaitis

JOSLIN DIABETES CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$631,027

FY 2026

Project Title

Maternal exercise during lactation to ignite infant metabolism

Grant Number:

5R01HD117197-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/22/2025

End Date:

3/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Breastfeeding reduces risk of childhood obesity and diabetes, but the mechanisms remain unclear. We recently identified that 12,13-diHOME, a signaling lipid crucial for activating brown adipocyte thermogenesis, is present in human milk. We reported that higher concentration ...

Research Terms

<2-ketoglutarate><2-oxoglutarate><3 Hydroxybutyrate><Acute><Adipocytes><Adipose Cell><Adipose tissue><Affect><Anatomic Sites><Anatomic structures><Anatomy><BMI><BMI percentile><BMI z-score><Blood Plasma><Blood Serum><Body Composition><Body mass index><Breast Epithelial Cells><Breast Feeding><Breast Milk><Breastmilk><Brown Adipose Tissue><Brown Fat><Cell Communication and Signaling><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cell Signaling><Childhood diabetes><Chronic><Clinical Trials><Collection><Consumption><Control Groups><DEXA><DXA><Data><Development><Diet><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Exclusive Breastfeeding><Exercise><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Gene Transcription><Generalized Growth><Genetic Transcription><Goals><Growth><Heat Production><Heel><Hibernating Gland><Human Milk><Human Mother's Milk><Indirect Calorimetry><Infant><Infant Development><Intermediary Metabolism><Intervention><Intracellular Communication and Signaling><Lactation><Life><Link><Linoleic Acids><Lipids><Lipocytes><Mammary Gland Milk><Mature Lipocyte><Mature fat cell><Measures><Mediating><Messenger RNA><Metabolic><Metabolic Processes><Metabolism><Milk><Moderate Exercise><Modification><Monitor><Mother's Milk><Mothers><Nucleotide Metabolism - Reference Pathway><Nucleotide Metabolism Pathway><Nucleotide Sugars Metabolism><Nucleotide Sugars Metabolism Pathway><Nucleotides><Obesity><Outcome><Participant><Pathway interactions><Patient Recruitments><Pilot Projects><Pisum sativum><Plasma><Plasma Serum><Postpartum Period><Proteins><Quetelet index><RNA Expression><Randomized><Regulation><Reporting><Respiration Calorimetry><Rest><Reticuloendothelial System, Serum, Plasma><Risk Reduction><Sampling><Serum><Signal Transduction><Signal Transduction Pathway><Signal Transduction Systems><Signaling><Standardization><Testing><Thermogenesis><Thermographies><Thermography><Time><Tissue Growth><Transcription><Weight><adipogenesis><adipose><adiposity><alpha ketoglutarate><beta-Hydroxybutyrate><biological signal transduction><cell sorting><child adiposity><child obesity><childhood adiposity><childhood obesity><compare intervention><comparison intervention><corpulence><developmental><diabetes during childhood><diabetes in childhood><diabetes in children><diets><exercise intervention><experiment><experimental research><experimental study><experiments><fat metabolism><feeding><glucose metabolism><high BMI><high body mass index><lactating><lactational><lipid biosynthesis><lipid metabolism><lipidome><lipidomics><lipogenesis><mRNA><mammary epithelial cells><mammary gland epithelial cells><maternal adiposity><maternal milk><maternal obesity><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><moderate physical activity><obese children><obesity during childhood><obesity in children><obesity risk><ontogeny><participant recruitment><pathway><pea><pediatric diabetes><pediatric obesity><physical activity intervention><pilot study><post-partum><programs><protective effect><randomisation><randomization><randomly assigned><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><standard of care><sugar nucleotide><thermographic imaging><weights><white adipose tissue><yellow adipose tissue><α-ketoglutarate><α-oxoglutarate><αKG><β-Hydroxybutyrate>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael C. Rudolph

JOSLIN DIABETES CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$631,027

FY 2026

Project Title

Maternal exercise during lactation to ignite infant metabolism

Grant Number:

5R01HD117197-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/22/2025

End Date:

3/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Breastfeeding reduces risk of childhood obesity and diabetes, but the mechanisms remain unclear. We recently identified that 12,13-diHOME, a signaling lipid crucial for activating brown adipocyte thermogenesis, is present in human milk. We reported that higher concentration ...

Research Terms

<2-ketoglutarate><2-oxoglutarate><3 Hydroxybutyrate><Acute><Adipocytes><Adipose Cell><Adipose tissue><Affect><Anatomic Sites><Anatomic structures><Anatomy><BMI><BMI percentile><BMI z-score><Blood Plasma><Blood Serum><Body Composition><Body mass index><Breast Epithelial Cells><Breast Feeding><Breast Milk><Breastmilk><Brown Adipose Tissue><Brown Fat><Cell Communication and Signaling><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cell Signaling><Childhood diabetes><Chronic><Clinical Trials><Collection><Consumption><Control Groups><DEXA><DXA><Data><Development><Diet><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Exclusive Breastfeeding><Exercise><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Gene Transcription><Generalized Growth><Genetic Transcription><Goals><Growth><Heat Production><Heel><Hibernating Gland><Human Milk><Human Mother's Milk><Indirect Calorimetry><Infant><Infant Development><Intermediary Metabolism><Intervention><Intracellular Communication and Signaling><Lactation><Life><Link><Linoleic Acids><Lipids><Lipocytes><Mammary Gland Milk><Mature Lipocyte><Mature fat cell><Measures><Mediating><Messenger RNA><Metabolic><Metabolic Processes><Metabolism><Milk><Moderate Exercise><Modification><Monitor><Mother's Milk><Mothers><Nucleotide Metabolism - Reference Pathway><Nucleotide Metabolism Pathway><Nucleotide Sugars Metabolism><Nucleotide Sugars Metabolism Pathway><Nucleotides><Obesity><Outcome><Participant><Pathway interactions><Patient Recruitments><Pilot Projects><Pisum sativum><Plasma><Plasma Serum><Postpartum Period><Proteins><Quetelet index><RNA Expression><Randomized><Regulation><Reporting><Respiration Calorimetry><Rest><Reticuloendothelial System, Serum, Plasma><Risk Reduction><Sampling><Serum><Signal Transduction><Signal Transduction Pathway><Signal Transduction Systems><Signaling><Standardization><Testing><Thermogenesis><Thermographies><Thermography><Time><Tissue Growth><Transcription><Weight><adipogenesis><adipose><adiposity><alpha ketoglutarate><beta-Hydroxybutyrate><biological signal transduction><cell sorting><child adiposity><child obesity><childhood adiposity><childhood obesity><compare intervention><comparison intervention><corpulence><developmental><diabetes during childhood><diabetes in childhood><diabetes in children><diets><exercise intervention><experiment><experimental research><experimental study><experiments><fat metabolism><feeding><glucose metabolism><high BMI><high body mass index><lactating><lactational><lipid biosynthesis><lipid metabolism><lipidome><lipidomics><lipogenesis><mRNA><mammary epithelial cells><mammary gland epithelial cells><maternal adiposity><maternal milk><maternal obesity><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><moderate physical activity><obese children><obesity during childhood><obesity in children><obesity risk><ontogeny><participant recruitment><pathway><pea><pediatric diabetes><pediatric obesity><physical activity intervention><pilot study><post-partum><programs><protective effect><randomisation><randomization><randomly assigned><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><standard of care><sugar nucleotide><thermographic imaging><weights><white adipose tissue><yellow adipose tissue><α-ketoglutarate><α-oxoglutarate><αKG><β-Hydroxybutyrate>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Caitlin Grace Howe

DARTMOUTH COLLEGE, HANOVER, NH

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$630,055

FY 2026

Project Title

Metal Impacts on miRNAs in Human Milk and Contributions to Early Childhood Growth

Grant Number:

5R01ES036661-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/12/2025

End Date:

2/28/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Accelerated growth in early childhood increases risk for obesity, a leading cause of morbidity and mortality. Identifying factors that influence early programming of growth and adiposity is critical for addressing the current obesity epidemic. This is especially important for rural p...

Research Terms

<0-11 years old><21+ years old><3 year old><3 years of age><Acceleration><Address><Adult><Adult Human><Affect><Animals><Archives><Arsenic><Autoregulation><BMI><BMI percentile><BMI z-score><Biology><Birth><Body Composition><Body Tissues><Body mass index><Breast Feeding><Breast Milk><Breastmilk><California><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cessation of life><Child><Child Youth><Childhood><Children (0-21)><Chronic Disease><Chronic Illness><Circulation><Clinical><Clip><Conceptions><Consumption><DEXA><DNA Methylation><DXA><Data><Death><Development><Digestion><Disparities><Disparity><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Endocrine><Endocrine disruption><Environmental Health><Environmental Health Science><Environmental Toxin><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Fats><Fatty acid glycerol esters><Gene Expression><Generalized Growth><Gestation><Growth><Guidelines><Health><High Prevalence><Homeostasis><Housing><Human Milk><Human Mother's Milk><In Vitro><Individual><Infant><Intervention><Intracellular Communication and Signaling><Lactation><Latino><Leanness><Length><Life><Longitudinal Studies><Longitudinal Surveys><Macronutrients><Macronutrients Nutrition><Mammary Gland Milk><Mammary gland><Measures><Mediating><Metabolic><Metal exposure><Metals><Methods><Methylation><MicroRNAs><Milk><Modeling><Morbidity><Mother's Milk><Mothers><NICHD><NIEHS><NIH><National Institute of Child Health and Human Development><National Institute of Environmental Health Sciences><National Institutes of Health><New England><New Hampshire><Northeastern United States><Nutrition Research><Nutritional Study><Obesity><Obesity Epidemic><Overweight><Participant><Parturition><Pattern><Peripheral><Physiological Homeostasis><Pilot Projects><Play><Population><Postpartum Period><Predisposition><Pregnancy><Prevalence><Preventative intervention><Privatization><Quetelet index><RNA Seq><RNA sequencing><RNAseq><Regulation><Reporting><Research><Role><Rural><Rural Population><Rural group><Rural people><Sampling><Sea-Food><Seafood><Signal Transduction><Signal Transduction Systems><Signaling><Source><Strategic Planning><Structure of nail of toe><Susceptibility><Systems Biology><Testing><Thinness><Time><Tissue Growth><Tissues><Toe Nail><Toenail><Toxic Environmental Agents><Toxic Environmental Substances><Toxicant exposure><United States National Institutes of Health><Validation><Weight><adipogenesis><adiposity><adulthood><age 3><age 3 years><arsenics><biological signal transduction><birth cohort study><birth cohort survey><breast epithelium><child adiposity><child obesity><childhood adiposity><childhood obesity><chronic disorder><cohort><corpulence><developmental><drinking water><early childhood><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><endocrine disrupting><energy balance><environmental toxicant><epigenetically><experiment><experimental research><experimental study><experiments><exposed in utero><exposure to metal><extracellular vesicles><fetal exposure><genome scale><genome-wide><genomewide><improved><in utero exposure><infancy><infantile><intervention for prevention><intra-uterine environmental exposure><intrauterine environmental exposure><kids><lactating><lactational><lipid biosynthesis><lipogenesis><long-term study><longitudinal outcome studies><longitudinal research study><mammary><mammary epithelium><maternal milk><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><miRNA><microbiome><mortality><novel><obese children><obesity during childhood><obesity in children><obesity risk><offspring><ontogeny><particle><pediatric><pediatric obesity><pilot study><post-partum><pregnant><premature><prematurity><prenatal exposure><prenatally exposed><prevention intervention><preventional intervention strategy><preventive intervention><risk for obesity><risk of obesity><rural area><rural individual><rural location><rural region><screening><screenings><social role><three year old><three years of age><toxic exposure><toxicant><transcriptome sequencing><transcriptomic sequencing><urban disparity><validations><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LINDA Anne BARBOUR

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$628,340

FY 2026

Project Title

Triglycerides as a Predictor of Newborn Subcutaneous and Liver Fat: Contributors to Fetal Fat Accretion in Obese Pregnancies

Grant Number:

5R01HD102726-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/7/2021

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Despite more than 40 RCT interventional trials in pregnant women at risk for delivering large-for-gestational age (LGA) infants, there is currently no clearly effective treatment to reduce fetal overgrowth in overweight/obesity (OW/OB), which account for ~70% of pregnancies....

Research Terms

<0-4 weeks old><Accounting><Address><Adipocytes><Adipose Cell><Adverse Late Effects><Air><Attenuated><BMI><BMI percentile><BMI z-score><Birth><Birth Weight><Body mass index><C-Peptide><Cells Placenta-Tissue><Childhood><Chronologic Fetal Maturity><Clinical><Communities><Continuous Glucose Monitor><Cord Blood><D-Glucose><DEXA><DXA><Data><Development><Dextrose><Diabetes Mellitus><Diagnosis><Diet><Differences between sexes><Differs between sexes><Discipline of obstetrics><Dose><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Exhibits><Fasting><Fat Cells><Fat progenitor cell><Fat stem cell><Fats><Fatty Acids><Fatty acid glycerol esters><Fetal Age><Fetal Growth><Fetal Macrosomia><Fetal Macrosomias><Fetus><Future><Generalized Growth><Gestation><Gestational Age><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Goals><Growth><High Risk Woman><Humulin R><Hyperinsulinemia><Hyperinsulinism><Infant><Insulin><Insulin Resistance><Intermediary Metabolism><Intervention Trial><Interventional trial><Late Effects><Late pregnancy><Life><Lipase><Lipid Trafficking><Lipids><Lipocytes><Liver><MR Spectroscopy><Magnetic Resonance Spectroscopy><Mature Lipocyte><Mature fat cell><Measures><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Monitor><Mothers><N-3 polyunsaturated fatty acid><NAFLD><Newborn Infant><Newborns><Non-Polyadenylated RNA><Normal Placentoma><Novolin R><Obesity><Obstetrics><Omega-3 Fatty Acids><Omega-3 PUFA><Omega-3 Polyunsaturated Fatty Acid><Outcome><Overweight><Pancreas><Pancreatic><Parturition><Pathway interactions><Placenta><Placenta Embryonic Tissue><Placentome><Plethysmography><Predictive Value><Pregnancy><Pregnancy-Induced Diabetes><Pregnant Women><Production><Progenitor Cells><Prospective cohort><Quetelet index><RNA><RNA Gene Products><Regular Insulin><Resistance profile><Resistant profile><Ribonucleic Acid><Risk><Risk Factors><Risk Reduction><Role><Sampling><Sex Differences><Sexual differences><Testing><Thesaurismosis><Time><Tissue Growth><Triacylglycerol><Triacylglycerol Hydrolase><Triacylglycerol Lipase><Triacylglycerol acylhydrolase><Tributyrinase><Triglyceridase><Triglyceride Lipase><Triglycerides><Triolean Hydrolase><Umbilical Cord><Umbilical Cord Blood><Umbilical Region><Umbilical cord structure><Umbilicus><Weight><Weight Gain><Weight Increase><Woman><Work><adipocyte progenitors><adipocyte stem cell><adipocyte-derived stem cell><adipose derived stem cell><adipose progenitor><adipose stem cell><adipose tissue derived stem cell><adipose tissue stem cells><adiposity><at-risk females><at-risk women><attenuate><attenuates><body weight gain><body weight increase><boys><child adiposity><child obesity><childhood adiposity><childhood obesity><connecting peptide><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><developmental><diabetes><diets><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><effective intervention><effective therapy><effective treatment><expectant mother><expectant women><expecting mother><expecting women><fasted><fasts><fat derived stem cell><fatty acid oxidation><fatty acid transport><females at high risk><fetal><fetal cord blood><fetal overgrowth><girls><glucometer><glucose meter><glucose monitor><hepatic body system><hepatic organ system><high risk females><in utero><individuals who are pregnant><insulin resistant><insulin tolerance><intergenerational><intra-uterine growth><intrahepatic><intrauterine growth><investigate retrospective><lipid transport><lipidomics><maternal adiposity><maternal obesity><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><metabolism disorder><meter><n-3 Fatty Acids><n-3 PUFA><neonatal adiposity><new approaches><newborn adiposity><newborn child><newborn children><newborn obesity><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-human primate><nonalcoholic fatty liver disease><nonhuman primate><novel approaches><novel strategies><novel strategy><obese children><obese mothers><obesity during childhood><obesity during pregnancy><obesity in children><obesity in pregnancy><obesity risk><omega-3><omega-3s><ontogeny><pathway><pediatric><pediatric obesity><people who are pregnant><portability><pregnancy diabetes><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><retrospective investigation><retrospective research><risk for obesity><risk of obesity><risk-reducing><sex><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><stem cells><study retrospective><subcutaneous><subdermal><survey retrospective><synergism><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><those who are pregnant><tributyrase><weights><women at high risk><women who are pregnant><wt gain>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Teri L Hernandez

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$628,340

FY 2026

Project Title

Triglycerides as a Predictor of Newborn Subcutaneous and Liver Fat: Contributors to Fetal Fat Accretion in Obese Pregnancies

Grant Number:

5R01HD102726-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/7/2021

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Despite more than 40 RCT interventional trials in pregnant women at risk for delivering large-for-gestational age (LGA) infants, there is currently no clearly effective treatment to reduce fetal overgrowth in overweight/obesity (OW/OB), which account for ~70% of pregnancies....

Research Terms

<0-4 weeks old><Accounting><Address><Adipocytes><Adipose Cell><Adverse Late Effects><Air><Attenuated><BMI><BMI percentile><BMI z-score><Birth><Birth Weight><Body mass index><C-Peptide><Cells Placenta-Tissue><Childhood><Chronologic Fetal Maturity><Clinical><Communities><Continuous Glucose Monitor><Cord Blood><D-Glucose><DEXA><DXA><Data><Development><Dextrose><Diabetes Mellitus><Diagnosis><Diet><Differences between sexes><Differs between sexes><Discipline of obstetrics><Dose><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Exhibits><Fasting><Fat Cells><Fat progenitor cell><Fat stem cell><Fats><Fatty Acids><Fatty acid glycerol esters><Fetal Age><Fetal Growth><Fetal Macrosomia><Fetal Macrosomias><Fetus><Future><Generalized Growth><Gestation><Gestational Age><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Goals><Growth><High Risk Woman><Humulin R><Hyperinsulinemia><Hyperinsulinism><Infant><Insulin><Insulin Resistance><Intermediary Metabolism><Intervention Trial><Interventional trial><Late Effects><Late pregnancy><Life><Lipase><Lipid Trafficking><Lipids><Lipocytes><Liver><MR Spectroscopy><Magnetic Resonance Spectroscopy><Mature Lipocyte><Mature fat cell><Measures><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Monitor><Mothers><N-3 polyunsaturated fatty acid><NAFLD><Newborn Infant><Newborns><Non-Polyadenylated RNA><Normal Placentoma><Novolin R><Obesity><Obstetrics><Omega-3 Fatty Acids><Omega-3 PUFA><Omega-3 Polyunsaturated Fatty Acid><Outcome><Overweight><Pancreas><Pancreatic><Parturition><Pathway interactions><Placenta><Placenta Embryonic Tissue><Placentome><Plethysmography><Predictive Value><Pregnancy><Pregnancy-Induced Diabetes><Pregnant Women><Production><Progenitor Cells><Prospective cohort><Quetelet index><RNA><RNA Gene Products><Regular Insulin><Resistance profile><Resistant profile><Ribonucleic Acid><Risk><Risk Factors><Risk Reduction><Role><Sampling><Sex Differences><Sexual differences><Testing><Thesaurismosis><Time><Tissue Growth><Triacylglycerol><Triacylglycerol Hydrolase><Triacylglycerol Lipase><Triacylglycerol acylhydrolase><Tributyrinase><Triglyceridase><Triglyceride Lipase><Triglycerides><Triolean Hydrolase><Umbilical Cord><Umbilical Cord Blood><Umbilical Region><Umbilical cord structure><Umbilicus><Weight><Weight Gain><Weight Increase><Woman><Work><adipocyte progenitors><adipocyte stem cell><adipocyte-derived stem cell><adipose derived stem cell><adipose progenitor><adipose stem cell><adipose tissue derived stem cell><adipose tissue stem cells><adiposity><at-risk females><at-risk women><attenuate><attenuates><body weight gain><body weight increase><boys><child adiposity><child obesity><childhood adiposity><childhood obesity><connecting peptide><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><developmental><diabetes><diets><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><effective intervention><effective therapy><effective treatment><expectant mother><expectant women><expecting mother><expecting women><fasted><fasts><fat derived stem cell><fatty acid oxidation><fatty acid transport><females at high risk><fetal><fetal cord blood><fetal overgrowth><girls><glucometer><glucose meter><glucose monitor><hepatic body system><hepatic organ system><high risk females><in utero><individuals who are pregnant><insulin resistant><insulin tolerance><intergenerational><intra-uterine growth><intrahepatic><intrauterine growth><investigate retrospective><lipid transport><lipidomics><maternal adiposity><maternal obesity><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><metabolism disorder><meter><n-3 Fatty Acids><n-3 PUFA><neonatal adiposity><new approaches><newborn adiposity><newborn child><newborn children><newborn obesity><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-human primate><nonalcoholic fatty liver disease><nonhuman primate><novel approaches><novel strategies><novel strategy><obese children><obese mothers><obesity during childhood><obesity during pregnancy><obesity in children><obesity in pregnancy><obesity risk><omega-3><omega-3s><ontogeny><pathway><pediatric><pediatric obesity><people who are pregnant><portability><pregnancy diabetes><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><retrospective investigation><retrospective research><risk for obesity><risk of obesity><risk-reducing><sex><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social role><stem cells><study retrospective><subcutaneous><subdermal><survey retrospective><synergism><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><those who are pregnant><tributyrase><weights><women at high risk><women who are pregnant><wt gain>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stacey Lynn Simon

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$625,508

FY 2026

Project Title

Mitigating cardiometabolic risk by improving sleep health and circadian timing in adolescents with overweight/obesity

Grant Number:

1R01DK142774-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The unique interplay of physiological, psychosocial, and behavioral factors of adolescence that result in circadian misalignment and dramatically insufficient sleep may confer a notable risk towards cardiometabolic impairment in youth. Our work and others have demonstrated that circa...

Research Terms

<12-20 years old><Actinotherapy><Acute><Adolescence><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Appetite><BMI><BMI percentile><BMI z-score><Beds><Behavioral><Biological><Blood Sample><Blood specimen><Body mass index><Caloric Intake><Cardiovascular Diseases><Circadian Rhythms><Circadian desynchrony><Continuous Glucose Monitor><Cross-Over Trials><Crossover Trials><D-Glucose><Data><Desire for food><Dextrose><Diet Records><Dietary Records><Dietary intake><Disinhibition><Dose><Eating><Endocrine Gland Secretion><Energy Expenditure><Energy Intake><Energy Metabolism><Environment><Exposure to><Fasting><Food Diaries><Food Intake><Future><Glass><Glucose><Health><Hormones><Hour><Hunger><Impairment><Insulin Resistance><Intake><Intervention><Ketosis-Resistant Diabetes Mellitus><L-tyrosyl-L-tyrosine><Laboratories><Light><Light Therapy><Maturity-Onset Diabetes Mellitus><Melatonin><Methodology><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nyctohemeral Rhythm><Obesity><Outcome><Overweight><PYY Peptide><Participant><Peptide YY><Phase><Photography><Photoradiation><Photoradiation Therapy><Phototherapy><Physiologic><Physiological><Prevention><Quetelet index><Randomized><Reporting><Risk><Risk Factors><Satiation><Schools><Sleep><Sleep Deprivation><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Testing><Therapeutic Hormone><Time><Total Daily Energy Expenditure><Twenty-Four Hour Rhythm><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Tyr-Tyr><Visit><Work><Youth><Youth 10-21><adequate sleep><adiposity><adolescence (12-20)><adult onset diabetes><awake><biologic><caloric dietary content><cardiometabolic><cardiometabolic risk><cardiometabolism><cardiovascular disorder><circadian><circadian clock><circadian desynchronization><circadian misalignment><circadian pacemaker><circadian process><circadian rhythmicity><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><daily biorhythm><deficient sleep><doubly-labeled water><eating in absence of hunger><energy balance><experience><fasted><fasts><ghrelin><high risk group><high risk individual><high risk people><high risk population><home based monitoring><home monitoring><improved><improvement on sleep><inadequate sleep><insufficient sleep><insulin resistant><insulin sensitivity><insulin tolerance><juvenile><juvenile human><ketosis resistant diabetes><life span><lifespan><light intervention><light treatment><maturity onset diabetes><novel><peptide tyrosine-tyrosine><portability><prevent><preventing><psychosocial><randomisation><randomization><randomly assigned><satiety><sleep amount><sleep debt><sleep deficiency><sleep deficit><sleep duration><sleep episode><sleep health><sleep hygiene><sleep improvement><sleep insufficiency><sleep interval><sleep length><sleep loss><sleep period><sleep quantity><sleep time><sleep wellness><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><tool><total energy expenditure><trial design><type 2 DM><type II DM><type two diabetes><tyrosyltyrosine><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bethany Barone Gibbs

UNIVERSITY OF IOWA, IOWA CITY, IA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$623,719

FY 2026

Project Title

Sedentary behavior, physical activity, and 24-hour behavior in pregnancy and offspring health: the Pregnancy 24/7 Offspring Study

Grant Number:

5R01HL164662-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/17/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Over the past three decades, there has been an alarming increase in the incidence of childhood obesity. Childhood obesity leads to early onset of cardiovascular risk factors, and both obesity and cardiovascular risk factors track into adulthood and contribute to the epidemic of cardiovascul...

Research Terms

<0-11 years old><1st trimester><21+ years old><Address><Adult><Adult Human><BMI><BMI percentile><BMI z-score><Behavior><Behavior assessment><Birth><Blood Pressure><Body mass index><Breast Feeding><Cardiovascular Diseases><Cause of Death><Child><Child Health><Child Youth><Childhood><Children (0-21)><Cohort Studies><Data><Data Analyses><Data Analysis><Development><Diet><Disease><Disorder><Early Placental Phase><Enrollment><Epidemic><Fetal Growth><First Pregnancy Trimester><First Trimester><Future><Generalized Growth><Gestation><Goals><Growth><Health><Home environment><Hour><Hypertension><Incidence><Intervention><Late pregnancy><Link><Maternal Behavior><Maternal Exposure><Maternal Health><Measurement><Measures><Medical Records><Methods><Modeling><Monitor><NHLBI><National Heart, Lung, and Blood Institute><Obesity><Outcome><Participant><Parturition><Pattern><Persons><Physical activity><Physiologic><Physiologic pulse><Physiological><Pregnancy><Pregnancy Trimesters><Pregnant Women><Preventative intervention><Prevention><Primary Prevention><Pulse><Questionnaires><Quetelet index><Research><Risk><Risk Factors><Risk Reduction><Role><Sedentary behavior><Sedentary life-style><Site><Sleep><Smoking><Statistical Methods><Time><Tissue Growth><Unhealthy Diet><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular aging><Visit><Woman><adiposity><adulthood><adverse pregnancy outcome><after pregnancy><behavioral assessment><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical relevance><clinically relevant><cohort research study><cohort survey><corpulence><data interpretation><developmental><diets><early childhood><early onset><enroll><expectant mother><expectant women><expecting mother><expecting women><exposed in utero><fetal exposure><fetal programming><gestational weight gain><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><in utero><in utero exposure><individuals who are pregnant><interest><intervention for prevention><intra-uterine environmental exposure><intra-uterine growth><intrauterine environmental exposure><intrauterine growth><kids><later in life><later life><life span><lifespan><modifiable behavior><novel><obese children><obesity during childhood><obesity in children><obesity risk><observational cohort study><offspring><offspring obesity><ontogeny><pediatric><pediatric obesity><people who are pregnant><poor diet><poor sleep><post pregnancy><postnatal><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prenatal exposure><prenatally exposed><prepregnancy obesity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary outcome><prospective><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><sedentary lifestyle><social role><statistic methods><theories><those who are pregnant><unborn><vasculature aging><vigorous intensity><women who are pregnant><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kara Marie Whitaker

UNIVERSITY OF IOWA, IOWA CITY, IA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$623,719

FY 2026

Project Title

Sedentary behavior, physical activity, and 24-hour behavior in pregnancy and offspring health: the Pregnancy 24/7 Offspring Study

Grant Number:

5R01HL164662-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/17/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Over the past three decades, there has been an alarming increase in the incidence of childhood obesity. Childhood obesity leads to early onset of cardiovascular risk factors, and both obesity and cardiovascular risk factors track into adulthood and contribute to the epidemic of cardiovascul...

Research Terms

<0-11 years old><1st trimester><21+ years old><Address><Adult><Adult Human><BMI><BMI percentile><BMI z-score><Behavior><Behavior assessment><Birth><Blood Pressure><Body mass index><Breast Feeding><Cardiovascular Diseases><Cause of Death><Child><Child Health><Child Youth><Childhood><Children (0-21)><Cohort Studies><Data><Data Analyses><Data Analysis><Development><Diet><Disease><Disorder><Early Placental Phase><Enrollment><Epidemic><Fetal Growth><First Pregnancy Trimester><First Trimester><Future><Generalized Growth><Gestation><Goals><Growth><Health><Home environment><Hour><Hypertension><Incidence><Intervention><Late pregnancy><Link><Maternal Behavior><Maternal Exposure><Maternal Health><Measurement><Measures><Medical Records><Methods><Modeling><Monitor><NHLBI><National Heart, Lung, and Blood Institute><Obesity><Outcome><Participant><Parturition><Pattern><Persons><Physical activity><Physiologic><Physiologic pulse><Physiological><Pregnancy><Pregnancy Trimesters><Pregnant Women><Preventative intervention><Prevention><Primary Prevention><Pulse><Questionnaires><Quetelet index><Research><Risk><Risk Factors><Risk Reduction><Role><Sedentary behavior><Sedentary life-style><Site><Sleep><Smoking><Statistical Methods><Time><Tissue Growth><Unhealthy Diet><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular aging><Visit><Woman><adiposity><adulthood><adverse pregnancy outcome><after pregnancy><behavioral assessment><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical relevance><clinically relevant><cohort research study><cohort survey><corpulence><data interpretation><developmental><diets><early childhood><early onset><enroll><expectant mother><expectant women><expecting mother><expecting women><exposed in utero><fetal exposure><fetal programming><gestational weight gain><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><in utero><in utero exposure><individuals who are pregnant><interest><intervention for prevention><intra-uterine environmental exposure><intra-uterine growth><intrauterine environmental exposure><intrauterine growth><kids><later in life><later life><life span><lifespan><modifiable behavior><novel><obese children><obesity during childhood><obesity in children><obesity risk><observational cohort study><offspring><offspring obesity><ontogeny><pediatric><pediatric obesity><people who are pregnant><poor diet><poor sleep><post pregnancy><postnatal><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prenatal exposure><prenatally exposed><prepregnancy obesity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary outcome><prospective><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><sedentary lifestyle><social role><statistic methods><theories><those who are pregnant><unborn><vasculature aging><vigorous intensity><women who are pregnant><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

anne peery

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$616,937

FY 2026

Project Title

A prospective cohort study to determine the role of obesity in diverticulitis

Grant Number:

5R01DK132050-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Colonic diverticulitis is a common (209 cases per 100,000 person-years) disease that is responsible for $5.5 billion dollars in health care expenditures annually. Diverticulitis is a leading indication for operations, hospital admissions, and ambulatory visits, with a greater burden ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michal Laniado Schwartzman

NEW YORK MEDICAL COLLEGE, VALHALLA, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$538,812

FY 2026

Project Title

GPR75 in obesity-driven cardiovascular and metabolic complications

Grant Number:

5R01HL168056-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Summary Obesity and the associated metabolic complications including metabolic syndrome and diabetes significantly contribute to cardiovascular morbidities. The overall goal of this proposal is aimed at identifying cellular mechanisms that link activation of the G-protein coupled receptor ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Adolfo Cuevas

NEW YORK UNIVERSITY, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$533,097

FY 2026

Project Title

Assessing the impact of exogenous stressors on obesity and pro-inflammatory gene expression

Grant Number:

5R01DK137246-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Obesity has been a persistent public health issue for decades. People with obesity experience higher risk of chronic diseases, such as diabetes, chronic kidney disease, hypertension, coronary heart disease, and stroke. Approximately 42% of adults in the United States currently have obesity. Yet, we ...

Research Terms

<21+ years old><Add Health><Address><Adipose tissue><Adolescent><Adolescent Youth><Adult><Adult Human><Affect><Aging><Apoplexy><BMI><BMI percentile><BMI z-score><Biologic Factor><Biological><Biological Factors><Biology><Blood leukocyte><Body Measures><Body mass index><Body measure procedure><Brain Vascular Accident><Buffers><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Cohort Studies><Coronary Disease><Coronary heart disease><Data><Development><Diabetes Mellitus><Dimensions><Etiology><Exposure to><Expression Signature><Fatty Tissue><Future><Gene Expression><Gene Expression Profile><Gene Transcription><Genetic Transcription><Goals><Health><Health and Retirement Study><High Prevalence><Hypertension><Individual><Inflammatory><Intervention><Investigators><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Life Cycle><Life Cycle Stages><Longitudinal Studies><Longitudinal Surveys><Marrow leukocyte><Measures><Mediating><Mediator><Metabolic><Molecular><Morbidity><National Longitudinal Study of Adolescent Health><National Longitudinal Survey of Adolescent to Adult Health><Obesity><Obesity associated disease><Obesity related disease><Outcome><Pathway interactions><Persons><Physiologic><Physiological><Play><Population><Preventative strategy><Prevention strategy><Preventive strategy><Process><Public Health><Quetelet index><RNA Expression><Research><Research Personnel><Researchers><Risk><Risk Reduction><Role><Sampling><Science><Shapes><Stress><Stroke><Subgroup><Testing><Transcription><United States><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><White Blood Cells><White Cell><Work><adipose><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><age associated><age associated disease><age associated disorder><age associated impairment><age correlated><age dependent><age dependent disease><age dependent disorder><age dependent impairment><age linked><age related><age related human disease><age specific><age-related disease><age-related disorder><age-related impairment><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><aging population><biologic><brain attack><causation><cerebral vascular accident><cerebrovascular accident><chronic disorder><chronic kidney disease><cohort><cohort research study><cohort survey><coronary disorder><corpulence><design><designing><developmental><diabetes><disease causation><excessive weight gain><experience><extreme weight gain><gene expression pattern><gene expression signature><healthy weight><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><inflammation marker><inflammatory marker><juvenile><juvenile human><life course><long-term study><longitudinal outcome studies><longitudinal research study><mid life><mid-life><middle age><middle aged><midlife><molecular biomarker><molecular marker><mortality><novel><obesigenic><obesity prevention><obesity risk><obesogenic><older adult><older adulthood><pathway><population aging><population based><prevent obesity><protective factors><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><serious weight gain><severe weight gain><social role><stem><stressor><stroked><strokes><transcriptional profile><transcriptional signature><treatment strategy><waist circumference><white adipose tissue><white blood cell><white blood corpuscle><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Linus Tzu-Yen Tsai

BETH ISRAEL DEACONESS MEDICAL CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$514,655

FY 2026

Project Title

The role of interferon regulatory factors in tanycytes during HFD-induced inflammation, obesity and glucose dysregulation

Grant Number:

5R01DK128406-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Abstract The arcuate nucleus-median eminence complex (Arc-ME) is an evolutionarily conserved region of the hypothalamus that plays important roles in physiology and behavior, including control of appetite, energy balance, insulin sensitivity, fertility and lactation. In rodent models, the in...

Research Terms

<21+ years old><ATAC sequencing><ATAC-seq><ATACseq><Address><Adult><Adult Human><Anatomic Sites><Anatomic structures><Anatomy><Appetite><Arcuate Nucleus><Assay for Transposase-Accessible Chromatin using sequencing><Astrocytes><Astrocytus><Astroglia><Atlases><Autopsy><Autoregulation><Behavior><Blood - brain barrier anatomy><Blood Circulation><Blood-Brain Barrier><Bloodstream><Body Tissues><Brain><Brain Nervous System><C-jun Amino-Terminal Kinase><C-jun Kinase-1><C-jun N-Terminal Kinase 1><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><CUT&RUN><Cas nuclease technology><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Function><Cell Interaction><Cell Line><Cell Physiology><Cell Process><Cell Signaling><Cell-to-Cell Interaction><CellLine><Cells><Cellular Function><Cellular Physiology><Cellular Process><Ceramides><Circulation><Cleavage Targets and Release Using Nuclease><Cleavage Under Targets and Release Using Nuclease><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Communication><Complex><Continuous Capillary><Cues><D-Glucose><Data><Desire for food><Dextrose><Disparate><Drug Therapy><ER stress><Encephalon><Endothelium><Ependymal Cell><Ependymocyte><Epidemic><Face><Fecundability><Fecundity><Fenestrated Capillary><Fertility><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Genes><Genetic Models><Genetic study><Glucose><Health Care Systems><Hemato-Encephalic Barrier><High Fat Diet><Homeostasis><Homolog of Drosophila TOLL><Hortega cell><Human><Hypothalamic structure><Hypothalamus><IFN><IFN activation><IFN-regulatory factor 3><IRF-3 protein><IRF3><IRF3 gene><Infiltration><Inflammation><Inflammatory><Inflammatory Response><Infundibular Nucleus><Insulin Resistance><Interferon Activation><Interferon Regulatory Factor 3><Interferons><Intracellular Communication and Signaling><JN Kinase><JNK><JNK Mitogen-Activated Protein Kinases><JNK1><JNK1 Kinase><JNK1 protein><JNK1A2><JNK21B1/2><Lactation><Life><Location><LoxP-flanked allele><MAP Kinase 8><MAP Kinase 8 Gene><MAPK8><MAPK8 Mitogen-Activated Protein Kinase><MAPK8 gene><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Mediating><Mediator><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic dysfunction><Methods><Mice><Mice Mammals><Microglia><Mitogen-Activated Protein Kinase 8><Modeling><Modern Man><Molecular><Molecular Target><Murine><Mus><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Network Analysis><Neural Cell><Neurocyte><Neurons><Non-Polyadenylated RNA><Nuclear Magnetic Resonance Imaging><Nutritional><Obesity><Overnutrition><PRKM8><Participant><Pathologic><Pathway Analysis><Pathway interactions><Peripheral><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiologic><Physiological><Physiological Homeostasis><Physiology><Play><Position><Positioning Attribute><Process><RNA><RNA Gene Products><RNA Seq><RNA sequencing><RNAseq><Receptor Protein><Regulation><Regulatory Element><Ribonucleic Acid><Rodent Model><Role><SAP Kinase-1><SAPK/JNK><SAPK1 Mitogen-Activated Protein Kinase><SAPK1/JNK><Sentinel><Side><Signal Transduction><Signal Transduction Systems><Signaling><Single cell seq><Single-Nucleus Sequencing><Strains Cell Lines><Stress-Activated Protein Kinase JNK1><Stress-Activated Protein Kinase gamma><Structure of nucleus infundibularis hypothalami><Subcellular Process><TLR4><TLR4 gene><Testing><Therapeutic><Tissues><Toll Homologue><Transcript Expression Analyses><Transcript Expression Analysis><Transcription Activation><Transcriptional Activation><Ventricular><Weight Gain><Weight Increase><Work><Zeugmatography><adiposity><adulthood><analyze gene expression><assay for transposase accessible chromatin followed by sequencing><assay for transposase accessible chromatin seq><assay for transposase accessible chromatin sequencing><assay for transposase-accessible chromatin with sequencing><astrocytic glia><biological signal transduction><bloodbrain barrier><body weight gain><body weight increase><brain parenchyma><c-jun N-Terminal Kinase><cell type><combat><constitutive expression><constitutive gene expression><corpulence><cultured cell line><design><designing><drug intervention><drug treatment><endoplasmic reticulum stress><energy balance><epigenome profiling><epigenomic profiling><faces><facial><floxed><floxed allele><gene expression analysis><gene expression assay><gitter cell><glucose metabolism><hypothalamic><improved><insulin resistant><insulin sensitivity><insulin tolerance><jun-NH2-Terminal Kinase><knockout gene><lactating><lactational><median eminence><mesoglia><metabolic phenotype><metabotype><microglial cell><microgliocyte><necropsy><neurogenesis><neuronal><nutritious><obesity-promoting diet><obesogenic Western-style diet><obesogenic diet><obesogenic high fat diet><obesogenic western diet><passive transport><pathway><peripheral blood><perivascular glial cell><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><postmortem><pro-obesity diet><progenitor cell niche><progenitor niche><programs><receptor><response><sNuc-Seq><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell next generation sequencing><single cell sequencing><single cell transcriptomic profiling><single nucleus RNA-sequencing><single nucleus seq><single-cell RNA sequencing><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><social role><stem and progenitor cell niche><stem cell niche><stress-activated protein kinase 1><toll-like receptor 4><transcriptional profiling><transcriptome sequencing><transcriptomic sequencing><wt gain>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ashley Nicole Battarbee

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,934,914

FY 2026

Project Title

10-Year Follow-Up of the Medical Optimization and Management of Pregnancies with Overt Type 2 Diabetes (MOMPOD FU) Study

Grant Number:

1R01DK145796-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/4/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

In the U.S., more than 1 in 5 children have obesity, and 1 in 5 adolescents have prediabetes, with rapidly rising rates of youth-onset type 2 diabetes (T2D) and significant impacts on long-term health and mortality. One of the key risk factors for development of childhood obesity and diabetes is exp...

Research Terms

<0-11 years old><10 year old><10 years of age><11 year old><11 years of age><2 year old><2 years of age><21+ years old><5 year old><5 years of age><ACOG><Active Follow-up><Address><Adjuvant Therapy><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><BMI><BMI percentile><BMI z-score><Beta Cell><Birth Weight><Black><Black race><Blinded><Blood><Blood Pressure><Blood Reticuloendothelial System><Body mass index><Cardiometabolic Disease><Cardiometabolic Disorder><Cell Function><Cell Physiology><Cell Process><Cells Placenta-Tissue><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Health><Child Youth><Childhood><Childhood diabetes><Children (0-21)><Chronologic Fetal Maturity><Collaborations><Continuous Glucose Monitor><D-Glucose><DEXA><DXA><Data><Data Coordinating Center><Data Coordination Center><Development><Dextrose><Diabetes Mellitus><Diagnosis><Dimethylbiguanidine><Dimethylguanylguanidine><Drugs><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Effectiveness><Eligibility><Eligibility Determination><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Fasting><Fats><Fatty acid glycerol esters><Female><Fetal Age><Follow-Up Studies><Foundations><Functional disorder><Future><Gestation><Gestational Age><Glucose><Goals><Government><HDL Cholesterol><HDL Cholesterol Lipoproteins><Health><High Density Lipoprotein Cholesterol><High Prevalence><Hispanic><Hour><Humulin R><Hyperglycemia><Image><Incidence><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insurance><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Long-Term Effects><Longitudinal Studies><Longitudinal Surveys><Low Birth Weight Infant><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medication><Metabolic syndrome><Metformin><Methodology><Muscle><Muscle Tissue><N,N-dimethyl-imidodicarbonimidic diamide><NHANES><NIDDM><National Health and Nutrition Examination Survey><Neonatal><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Novolin R><OGTT><Obesity><Oral Glucose Tolerance Test><Outcome><Participant><Persons><Pharmaceutical Preparations><Phenotype><Physiopathology><Placebos><Placenta><Placenta Embryonic Tissue><Placentome><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy><Pregnancy in Diabetes><Pregnancy in Diabetics><Pregnant Women><Protocol Screening><Quetelet index><Randomized><Recommendation><Regular Insulin><Research><Research Specimen><Risk><Risk Factors><Safety><Sham Treatment><Shapes><Site><Skinfold Thickness><Slow-Onset Diabetes Mellitus><Specimen><Stable Diabetes Mellitus><Subcellular Process><T2 DM><T2D><T2DM><Test Result><Testing><Thinness><Time><Transmission><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Woman><Youth><Youth 10-21><active followup><adiposity><adjuvant treatment><adult onset diabetes><adult youth><adulthood><age 10><age 10 years><age 11><age 11 years><age 2><age 2 years><age 5><age 5 years><aged 2 years><aged two years><ages><alpha-Lipoprotein Cholesterol><cardiometabolic><cardiometabolism><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><design><designing><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug/agent><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><eleven year old><eleven years of age><enroll><epigenetically><expectant mother><expectant women><expecting mother><expecting women><experience><fasted><fasting glucose><fasts><five year old><five years of age><follow up><follow-up><follow-up research study><follow-up survey><followed up><followup><glycemic control><high BMI><high body mass index><hyperglycemic><imaging><improved><improved outcome><in utero><individuals who are pregnant><innovate><innovation><innovative><insight><insulin resistant><insulin tolerance><intergenerational><juvenile><juvenile human><ketosis resistant diabetes><kids><long-term study><longitudinal outcome studies><longitudinal research study><low birth weight><low birthweight><male><maternal condition><maturity onset diabetes><mortality><multidisciplinary><muscular><neonatal morbidity><neonate><newborn morbidity><obese children><obesity during childhood><obesity in children><offspring><pathophysiology><pediatric><pediatric diabetes><pediatric obesity><people who are pregnant><pre-diabetes><pre-diabetic><prediabetic><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><programs><randomisation><randomization><randomly assigned><sex><sham therapy><skin fold measurement><skin fold thickness><skinfold measurement><study with follow-up><ten year old><ten years of age><those who are pregnant><transmission process><treatment trial><two year old><two years of age><type 2 DM><type II DM><type two diabetes><waist circumference><women who are pregnant><young adult><young adult age><young adulthood><youngster><youth age><β-cell><β-cells><βCell><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Paula Catherine Chandler-Laney

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,934,914

FY 2026

Project Title

10-Year Follow-Up of the Medical Optimization and Management of Pregnancies with Overt Type 2 Diabetes (MOMPOD FU) Study

Grant Number:

1R01DK145796-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/4/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

In the U.S., more than 1 in 5 children have obesity, and 1 in 5 adolescents have prediabetes, with rapidly rising rates of youth-onset type 2 diabetes (T2D) and significant impacts on long-term health and mortality. One of the key risk factors for development of childhood obesity and diabetes is exp...

Research Terms

<0-11 years old><10 year old><10 years of age><11 year old><11 years of age><2 year old><2 years of age><21+ years old><5 year old><5 years of age><ACOG><Active Follow-up><Address><Adjuvant Therapy><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><BMI><BMI percentile><BMI z-score><Beta Cell><Birth Weight><Black><Black race><Blinded><Blood><Blood Pressure><Blood Reticuloendothelial System><Body mass index><Cardiometabolic Disease><Cardiometabolic Disorder><Cell Function><Cell Physiology><Cell Process><Cells Placenta-Tissue><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Health><Child Youth><Childhood><Childhood diabetes><Children (0-21)><Chronologic Fetal Maturity><Collaborations><Continuous Glucose Monitor><D-Glucose><DEXA><DXA><Data><Data Coordinating Center><Data Coordination Center><Development><Dextrose><Diabetes Mellitus><Diagnosis><Dimethylbiguanidine><Dimethylguanylguanidine><Drugs><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Effectiveness><Eligibility><Eligibility Determination><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Fasting><Fats><Fatty acid glycerol esters><Female><Fetal Age><Follow-Up Studies><Foundations><Functional disorder><Future><Gestation><Gestational Age><Glucose><Goals><Government><HDL Cholesterol><HDL Cholesterol Lipoproteins><Health><High Density Lipoprotein Cholesterol><High Prevalence><Hispanic><Hour><Humulin R><Hyperglycemia><Image><Incidence><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insurance><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Long-Term Effects><Longitudinal Studies><Longitudinal Surveys><Low Birth Weight Infant><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medication><Metabolic syndrome><Metformin><Methodology><Muscle><Muscle Tissue><N,N-dimethyl-imidodicarbonimidic diamide><NHANES><NIDDM><National Health and Nutrition Examination Survey><Neonatal><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Novolin R><OGTT><Obesity><Oral Glucose Tolerance Test><Outcome><Participant><Persons><Pharmaceutical Preparations><Phenotype><Physiopathology><Placebos><Placenta><Placenta Embryonic Tissue><Placentome><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy><Pregnancy in Diabetes><Pregnancy in Diabetics><Pregnant Women><Protocol Screening><Quetelet index><Randomized><Recommendation><Regular Insulin><Research><Research Specimen><Risk><Risk Factors><Safety><Sham Treatment><Shapes><Site><Skinfold Thickness><Slow-Onset Diabetes Mellitus><Specimen><Stable Diabetes Mellitus><Subcellular Process><T2 DM><T2D><T2DM><Test Result><Testing><Thinness><Time><Transmission><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Woman><Youth><Youth 10-21><active followup><adiposity><adjuvant treatment><adult onset diabetes><adult youth><adulthood><age 10><age 10 years><age 11><age 11 years><age 2><age 2 years><age 5><age 5 years><aged 2 years><aged two years><ages><alpha-Lipoprotein Cholesterol><cardiometabolic><cardiometabolism><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><design><designing><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug/agent><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><eleven year old><eleven years of age><enroll><epigenetically><expectant mother><expectant women><expecting mother><expecting women><experience><fasted><fasting glucose><fasts><five year old><five years of age><follow up><follow-up><follow-up research study><follow-up survey><followed up><followup><glycemic control><high BMI><high body mass index><hyperglycemic><imaging><improved><improved outcome><in utero><individuals who are pregnant><innovate><innovation><innovative><insight><insulin resistant><insulin tolerance><intergenerational><juvenile><juvenile human><ketosis resistant diabetes><kids><long-term study><longitudinal outcome studies><longitudinal research study><low birth weight><low birthweight><male><maternal condition><maturity onset diabetes><mortality><multidisciplinary><muscular><neonatal morbidity><neonate><newborn morbidity><obese children><obesity during childhood><obesity in children><offspring><pathophysiology><pediatric><pediatric diabetes><pediatric obesity><people who are pregnant><pre-diabetes><pre-diabetic><prediabetic><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><programs><randomisation><randomization><randomly assigned><sex><sham therapy><skin fold measurement><skin fold thickness><skinfold measurement><study with follow-up><ten year old><ten years of age><those who are pregnant><transmission process><treatment trial><two year old><two years of age><type 2 DM><type II DM><type two diabetes><waist circumference><women who are pregnant><young adult><young adult age><young adulthood><youngster><youth age><β-cell><β-cells><βCell><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jeff M Szychowski

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,934,914

FY 2026

Project Title

10-Year Follow-Up of the Medical Optimization and Management of Pregnancies with Overt Type 2 Diabetes (MOMPOD FU) Study

Grant Number:

1R01DK145796-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/4/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

In the U.S., more than 1 in 5 children have obesity, and 1 in 5 adolescents have prediabetes, with rapidly rising rates of youth-onset type 2 diabetes (T2D) and significant impacts on long-term health and mortality. One of the key risk factors for development of childhood obesity and diabetes is exp...

Research Terms

<0-11 years old><10 year old><10 years of age><11 year old><11 years of age><2 year old><2 years of age><21+ years old><5 year old><5 years of age><ACOG><Active Follow-up><Address><Adjuvant Therapy><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><BMI><BMI percentile><BMI z-score><Beta Cell><Birth Weight><Black><Black race><Blinded><Blood><Blood Pressure><Blood Reticuloendothelial System><Body mass index><Cardiometabolic Disease><Cardiometabolic Disorder><Cell Function><Cell Physiology><Cell Process><Cells Placenta-Tissue><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Health><Child Youth><Childhood><Childhood diabetes><Children (0-21)><Chronologic Fetal Maturity><Collaborations><Continuous Glucose Monitor><D-Glucose><DEXA><DXA><Data><Data Coordinating Center><Data Coordination Center><Development><Dextrose><Diabetes Mellitus><Diagnosis><Dimethylbiguanidine><Dimethylguanylguanidine><Drugs><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Effectiveness><Eligibility><Eligibility Determination><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Fasting><Fats><Fatty acid glycerol esters><Female><Fetal Age><Follow-Up Studies><Foundations><Functional disorder><Future><Gestation><Gestational Age><Glucose><Goals><Government><HDL Cholesterol><HDL Cholesterol Lipoproteins><Health><High Density Lipoprotein Cholesterol><High Prevalence><Hispanic><Hour><Humulin R><Hyperglycemia><Image><Incidence><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insurance><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Long-Term Effects><Longitudinal Studies><Longitudinal Surveys><Low Birth Weight Infant><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medication><Metabolic syndrome><Metformin><Methodology><Muscle><Muscle Tissue><N,N-dimethyl-imidodicarbonimidic diamide><NHANES><NIDDM><National Health and Nutrition Examination Survey><Neonatal><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Novolin R><OGTT><Obesity><Oral Glucose Tolerance Test><Outcome><Participant><Persons><Pharmaceutical Preparations><Phenotype><Physiopathology><Placebos><Placenta><Placenta Embryonic Tissue><Placentome><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy><Pregnancy in Diabetes><Pregnancy in Diabetics><Pregnant Women><Protocol Screening><Quetelet index><Randomized><Recommendation><Regular Insulin><Research><Research Specimen><Risk><Risk Factors><Safety><Sham Treatment><Shapes><Site><Skinfold Thickness><Slow-Onset Diabetes Mellitus><Specimen><Stable Diabetes Mellitus><Subcellular Process><T2 DM><T2D><T2DM><Test Result><Testing><Thinness><Time><Transmission><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Woman><Youth><Youth 10-21><active followup><adiposity><adjuvant treatment><adult onset diabetes><adult youth><adulthood><age 10><age 10 years><age 11><age 11 years><age 2><age 2 years><age 5><age 5 years><aged 2 years><aged two years><ages><alpha-Lipoprotein Cholesterol><cardiometabolic><cardiometabolism><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><design><designing><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug/agent><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><eleven year old><eleven years of age><enroll><epigenetically><expectant mother><expectant women><expecting mother><expecting women><experience><fasted><fasting glucose><fasts><five year old><five years of age><follow up><follow-up><follow-up research study><follow-up survey><followed up><followup><glycemic control><high BMI><high body mass index><hyperglycemic><imaging><improved><improved outcome><in utero><individuals who are pregnant><innovate><innovation><innovative><insight><insulin resistant><insulin tolerance><intergenerational><juvenile><juvenile human><ketosis resistant diabetes><kids><long-term study><longitudinal outcome studies><longitudinal research study><low birth weight><low birthweight><male><maternal condition><maturity onset diabetes><mortality><multidisciplinary><muscular><neonatal morbidity><neonate><newborn morbidity><obese children><obesity during childhood><obesity in children><offspring><pathophysiology><pediatric><pediatric diabetes><pediatric obesity><people who are pregnant><pre-diabetes><pre-diabetic><prediabetic><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><programs><randomisation><randomization><randomly assigned><sex><sham therapy><skin fold measurement><skin fold thickness><skinfold measurement><study with follow-up><ten year old><ten years of age><those who are pregnant><transmission process><treatment trial><two year old><two years of age><type 2 DM><type II DM><type two diabetes><waist circumference><women who are pregnant><young adult><young adult age><young adulthood><youngster><youth age><β-cell><β-cells><βCell><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Brigid Ellen Gregg

LURIE CHILDREN'S HOSPITAL OF CHICAGO, CHICAGO, IL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,816,987

FY 2026

Project Title

The GROWTH Study, Glycemia Range and Offspring Weight and adiposity in response To Human milk

Grant Number:

5R01HD109260-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Maternal metabolism during pregnancy is a key contributor to developmental origins of metabolic disease. Offspring exposed to maternal hyperglycemia and obesity have increased rates of obesity and disordered glucose metabolism. The lactation period is also a critical window for programming....

Research Terms

<0-11 years old><2 year old><2 years of age><Accounting><Address><Adipocyte precursor><Adipocytes><Adipose Cell><Anabolism><Ancillary Study><BMI><BMI percentile><BMI z-score><Beta Cell><Body Composition><Body fat><Body mass index><Breast Epithelial Cells><Breast Feeding><Breast Milk><Breastmilk><Categories><Cell Body><Cells><Child><Child Youth><Childhood><Children (0-21)><D-Glucose><Development><Dextrose><Diet><Dissection><Dysfunction><Enrollment><Environment><Exposure to><Expression Signature><Fat Cells><Fatty Acids><Follow-Up Studies><Food><Functional disorder><Funding><Gene Expression><Gene Expression Profile><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Glucose Metabolic Disorders><Glucose Metabolism Disorders><Goals><Growth><Health><Hexadecanoic Acid><Human><Human Milk><Human Mother's Milk><Hyperglycemia><Hypertrophy><Infant><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intermediary Metabolism><Intervention><Knowledge><Lactation><Length><Linoleic Acids><Linolenic Acids><Lipids><Lipocytes><Mammary Gland Milk><Maternal Nutrition><Maternal diet><Mature Lipocyte><Mature fat cell><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Milk><Modeling><Modern Man><Mother's Milk><Mothers><NICHD><NIH><National Institute of Child Health and Human Development><National Institutes of Health><Nutrient><Nutrition><Obesity><Octadecatrienoic Acid><Outcome><Palmitic Acids><Pathologic><Pathway interactions><Phenotype><Physiopathology><Postpartum Period><Preadipocytes><Precursor to adipocyte><Predisposition><Pregnancy><Pregnancy-Induced Diabetes><Public Health><Quetelet index><Regulation><Reproducibility><Research><Risk><Risk Reduction><Sampling><Scientist><Shapes><Susceptibility><Testing><Thesaurismosis><Time><Tissue Growth><Translational Research><Translational Science><United States National Institutes of Health><Validation><Variant><Variation><Weight><Woman><adipocyte development><adipocyte differentiation><adipogenesis><adiposity><adverse pregnancy outcome><after pregnancy><age 2><age 2 years><aged 2 years><aged two years><biosynthesis><cardiometabolic risk><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><developmental><diets><early childhood><enroll><experience><exposed in utero><fat cell precursor><fetal exposure><follow-up research study><follow-up survey><gene expression pattern><gene expression signature><high BMI><high body mass index><hyperglycemic><improved><in utero><in utero exposure><in vitro testing><infant adiposity><infant obesity><infantile obesity><insulin resistant><insulin tolerance><inter-individual variability><inter-individual variation><intra-uterine environmental exposure><intrauterine environmental exposure><kids><lactating><lactation period><lactational><lactogenesis><lactogenic><lipid biosynthesis><lipogenesis><mammary epithelial cells><mammary gland development><mammary gland epithelial cells><mammary gland morphogenesis><mammary morphogenesis><maternal adiposity><maternal condition><maternal diabetes><maternal hyperglycemia><maternal milk><maternal nutrition during pregnancy><maternal obesity><metabolic phenotype><metabolism disorder><metabotype><mother nutrition><novel><obese children><obesity among infants><obesity during childhood><obesity in children><obesity in infants><offspring><ontogeny><pathophysiology><pathway><pediatric><pediatric obesity><post pregnancy><post-partum><pregnancy diabetes><prenatal exposure><prenatally exposed><prospective><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk-reducing><screening><screenings><study with follow-up><transcriptional profile><transcriptional signature><transcriptomics><translation research><translational investigation><translational study><two year old><two years of age><validations><weights><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jami L Josefson

LURIE CHILDREN'S HOSPITAL OF CHICAGO, CHICAGO, IL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,816,987

FY 2026

Project Title

The GROWTH Study, Glycemia Range and Offspring Weight and adiposity in response To Human milk

Grant Number:

5R01HD109260-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Maternal metabolism during pregnancy is a key contributor to developmental origins of metabolic disease. Offspring exposed to maternal hyperglycemia and obesity have increased rates of obesity and disordered glucose metabolism. The lactation period is also a critical window for programming....

Research Terms

<0-11 years old><2 year old><2 years of age><Accounting><Address><Adipocyte precursor><Adipocytes><Adipose Cell><Anabolism><Ancillary Study><BMI><BMI percentile><BMI z-score><Beta Cell><Body Composition><Body fat><Body mass index><Breast Epithelial Cells><Breast Feeding><Breast Milk><Breastmilk><Categories><Cell Body><Cells><Child><Child Youth><Childhood><Children (0-21)><D-Glucose><Development><Dextrose><Diet><Dissection><Dysfunction><Enrollment><Environment><Exposure to><Expression Signature><Fat Cells><Fatty Acids><Follow-Up Studies><Food><Functional disorder><Funding><Gene Expression><Gene Expression Profile><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Glucose Metabolic Disorders><Glucose Metabolism Disorders><Goals><Growth><Health><Hexadecanoic Acid><Human><Human Milk><Human Mother's Milk><Hyperglycemia><Hypertrophy><Infant><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intermediary Metabolism><Intervention><Knowledge><Lactation><Length><Linoleic Acids><Linolenic Acids><Lipids><Lipocytes><Mammary Gland Milk><Maternal Nutrition><Maternal diet><Mature Lipocyte><Mature fat cell><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Milk><Modeling><Modern Man><Mother's Milk><Mothers><NICHD><NIH><National Institute of Child Health and Human Development><National Institutes of Health><Nutrient><Nutrition><Obesity><Octadecatrienoic Acid><Outcome><Palmitic Acids><Pathologic><Pathway interactions><Phenotype><Physiopathology><Postpartum Period><Preadipocytes><Precursor to adipocyte><Predisposition><Pregnancy><Pregnancy-Induced Diabetes><Public Health><Quetelet index><Regulation><Reproducibility><Research><Risk><Risk Reduction><Sampling><Scientist><Shapes><Susceptibility><Testing><Thesaurismosis><Time><Tissue Growth><Translational Research><Translational Science><United States National Institutes of Health><Validation><Variant><Variation><Weight><Woman><adipocyte development><adipocyte differentiation><adipogenesis><adiposity><adverse pregnancy outcome><after pregnancy><age 2><age 2 years><aged 2 years><aged two years><biosynthesis><cardiometabolic risk><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><developmental><diets><early childhood><enroll><experience><exposed in utero><fat cell precursor><fetal exposure><follow-up research study><follow-up survey><gene expression pattern><gene expression signature><high BMI><high body mass index><hyperglycemic><improved><in utero><in utero exposure><in vitro testing><infant adiposity><infant obesity><infantile obesity><insulin resistant><insulin tolerance><inter-individual variability><inter-individual variation><intra-uterine environmental exposure><intrauterine environmental exposure><kids><lactating><lactation period><lactational><lactogenesis><lactogenic><lipid biosynthesis><lipogenesis><mammary epithelial cells><mammary gland development><mammary gland epithelial cells><mammary gland morphogenesis><mammary morphogenesis><maternal adiposity><maternal condition><maternal diabetes><maternal hyperglycemia><maternal milk><maternal nutrition during pregnancy><maternal obesity><metabolic phenotype><metabolism disorder><metabotype><mother nutrition><novel><obese children><obesity among infants><obesity during childhood><obesity in children><obesity in infants><offspring><ontogeny><pathophysiology><pathway><pediatric><pediatric obesity><post pregnancy><post-partum><pregnancy diabetes><prenatal exposure><prenatally exposed><prospective><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk-reducing><screening><screenings><study with follow-up><transcriptional profile><transcriptional signature><transcriptomics><translation research><translational investigation><translational study><two year old><two years of age><validations><weights><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Daniel T. Robinson

LURIE CHILDREN'S HOSPITAL OF CHICAGO, CHICAGO, IL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,816,987

FY 2026

Project Title

The GROWTH Study, Glycemia Range and Offspring Weight and adiposity in response To Human milk

Grant Number:

5R01HD109260-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Maternal metabolism during pregnancy is a key contributor to developmental origins of metabolic disease. Offspring exposed to maternal hyperglycemia and obesity have increased rates of obesity and disordered glucose metabolism. The lactation period is also a critical window for programming....

Research Terms

<0-11 years old><2 year old><2 years of age><Accounting><Address><Adipocyte precursor><Adipocytes><Adipose Cell><Anabolism><Ancillary Study><BMI><BMI percentile><BMI z-score><Beta Cell><Body Composition><Body fat><Body mass index><Breast Epithelial Cells><Breast Feeding><Breast Milk><Breastmilk><Categories><Cell Body><Cells><Child><Child Youth><Childhood><Children (0-21)><D-Glucose><Development><Dextrose><Diet><Dissection><Dysfunction><Enrollment><Environment><Exposure to><Expression Signature><Fat Cells><Fatty Acids><Follow-Up Studies><Food><Functional disorder><Funding><Gene Expression><Gene Expression Profile><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Glucose Metabolic Disorders><Glucose Metabolism Disorders><Goals><Growth><Health><Hexadecanoic Acid><Human><Human Milk><Human Mother's Milk><Hyperglycemia><Hypertrophy><Infant><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intermediary Metabolism><Intervention><Knowledge><Lactation><Length><Linoleic Acids><Linolenic Acids><Lipids><Lipocytes><Mammary Gland Milk><Maternal Nutrition><Maternal diet><Mature Lipocyte><Mature fat cell><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Milk><Modeling><Modern Man><Mother's Milk><Mothers><NICHD><NIH><National Institute of Child Health and Human Development><National Institutes of Health><Nutrient><Nutrition><Obesity><Octadecatrienoic Acid><Outcome><Palmitic Acids><Pathologic><Pathway interactions><Phenotype><Physiopathology><Postpartum Period><Preadipocytes><Precursor to adipocyte><Predisposition><Pregnancy><Pregnancy-Induced Diabetes><Public Health><Quetelet index><Regulation><Reproducibility><Research><Risk><Risk Reduction><Sampling><Scientist><Shapes><Susceptibility><Testing><Thesaurismosis><Time><Tissue Growth><Translational Research><Translational Science><United States National Institutes of Health><Validation><Variant><Variation><Weight><Woman><adipocyte development><adipocyte differentiation><adipogenesis><adiposity><adverse pregnancy outcome><after pregnancy><age 2><age 2 years><aged 2 years><aged two years><biosynthesis><cardiometabolic risk><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><developmental><diets><early childhood><enroll><experience><exposed in utero><fat cell precursor><fetal exposure><follow-up research study><follow-up survey><gene expression pattern><gene expression signature><high BMI><high body mass index><hyperglycemic><improved><in utero><in utero exposure><in vitro testing><infant adiposity><infant obesity><infantile obesity><insulin resistant><insulin tolerance><inter-individual variability><inter-individual variation><intra-uterine environmental exposure><intrauterine environmental exposure><kids><lactating><lactation period><lactational><lactogenesis><lactogenic><lipid biosynthesis><lipogenesis><mammary epithelial cells><mammary gland development><mammary gland epithelial cells><mammary gland morphogenesis><mammary morphogenesis><maternal adiposity><maternal condition><maternal diabetes><maternal hyperglycemia><maternal milk><maternal nutrition during pregnancy><maternal obesity><metabolic phenotype><metabolism disorder><metabotype><mother nutrition><novel><obese children><obesity among infants><obesity during childhood><obesity in children><obesity in infants><offspring><ontogeny><pathophysiology><pathway><pediatric><pediatric obesity><post pregnancy><post-partum><pregnancy diabetes><prenatal exposure><prenatally exposed><prospective><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk-reducing><screening><screenings><study with follow-up><transcriptional profile><transcriptional signature><transcriptomics><translation research><translational investigation><translational study><two year old><two years of age><validations><weights><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Craig Evan Pollack

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,585,406

FY 2026

Project Title

The Mobility Opportunity Voucher to Eliminate Diabetes and obesity (MOVED) Study

Grant Number:

5R01DK136610-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Modified Project Summary An estimated 41% of adults in the US and one in five of children are estimated to have obesity; over 37 million Americans have diabetes and 96 million adults have prediabetes. The prevalence of these conditions continue to grow, highlighting the need for policies addressing...

Research Terms

<0-11 years old><21+ years old><Accelerometer><Active Follow-up><Address><Adult><Adult Human><American><Application Context><BMI><BMI percentile><BMI z-score><Behavioral><Body mass index><Characteristics><Child><Child Youth><Children (0-21)><Chronic><Chronic Disease><Chronic Illness><Collaborations><Communities><Congresses><Control Groups><Data><Data Collection><Deposit><Deposition><Diabetes Mellitus><Diet><Enrollment><Exhibits><Experimental Designs><Family><Federal Government><Fees><Food><Funding><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Benefit><Hemoglobin A(1)><Household><Housing><Impoverished><Impoverished Areas><Impoverished Regions><Intervention><Interview><Knowledge><Literature><Low Income Population><Low income><Low income group><Measures><Mediating><Mental Health><Mental Hygiene><National Government><Neighborhoods><Obesity><Outcome><Participant><Pathway interactions><Persons><Physical activity><Play><Policies><Poverty><Poverty Areas><Poverty Regions><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Psychological Health><Psychosocial Factor><Questionnaires><Quetelet index><Randomized><Randomized, Controlled Trials><Research><Role><Sampling><Security><Services><Shapes><Site><Sleep><Social support><Survey Instrument><Surveys><Testing><Time><accelerometry><access to health care><accessibility of health care><accessibility to health care><active followup><activity monitor><activity tracker><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><arm><barriers to implementation><child adiposity><child obesity><childhood adiposity><childhood obesity><chronic disorder><compare to control><comparison control><contextual factors><corpulence><design><designing><diabetes><diabetes risk><diets><disease risk><disorder risk><enroll><experience><experiment><experimental research><experimental study><experiments><falls><follow up><follow-up><followed up><followup><health care access><health care availability><health care service access><health care service availability><hemoglobin A1c><hospitalization rates><implementation barriers><implementation challenges><improved><innovate><innovation><innovative><kids><life style intervention><lifestyle intervention><low income individual><low income people><lower income families><obese children><obesity during childhood><obesity in children><obesity risk><outreach><pathway><pediatric obesity><poverty stricken areas><pre-diabetes><pre-diabetic><prediabetic><programs><psychosocial><psychosocial variables><randomisation><randomization><randomized control trial><randomly assigned><recruit><risk for obesity><risk of obesity><social><social role><social support network><treatment group><voucher><walkability><walkable><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kathleen Alanna Page

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$845,922

FY 2026

Project Title

The Role of Gut-Brain Pathways on Childhood Obesity and Type 2 Diabetes Development

Grant Number:

1R01DK145940-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Childhood obesity and youth-onset type 2 diabetes (T2D) are increasing at an alarming rate, yet the underlying mechanisms remain poorly understood. Gut-derived hormones, including glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), peptide YY...

Research Terms

<0-11 years old><12-20 years old><21+ years old><7 year old><7 years of age><Address><Adolescence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Ammon Horn><Appetite><Appetite Regulation><BMI><BMI percentile><BMI z-score><Beta Cell><Body mass index><Brain><Brain Nervous System><Brain imaging><Brain region><Caloric Intake><Caring><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cellular Function><Cellular Physiology><Cellular Process><Central Lobe><Child><Child Youth><Childhood><Children (0-21)><Cornu Ammonis><Corpus Striatum><Corpus striatum structure><D-Glucose><Data><Desire for food><Development><Dextrose><Diabetes Mellitus><Diet><Dysfunction><Early Intervention><Encephalon><Endocrine Gland Secretion><Energy Intake><Exposure to><Female><Foundations><Functional disorder><Funding><GIP receptor><GLP-1><Gestational Diabetes><Gestational Diabetes Mellitus><Glp-1><Glucose><Glucose-Dependent Insulinotropic Polypeptide><Goals><Health><Hippocampus><Hormone secretion><Hormones><Hypothalamic structure><Hypothalamus><Impairment><Insula><Insula of Reil><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intervention><Intracellular Communication and Signaling><Island of Reil><Ketosis-Resistant Diabetes Mellitus><L-tyrosyl-L-tyrosine><Life Style><Lifestyle><Link><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Maturity-Onset Diabetes Mellitus><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Modeling><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrient><OGTT><Obesity><Oral><Oral Glucose Tolerance Test><Outcome><PYY Peptide><Participant><Pathway interactions><Peptide YY><Physical activity><Physiopathology><Play><Pregnancy-Induced Diabetes><Process><Quetelet index><Research><Research Design><Rewards><Risk><Risk Factors><Role><Satiation><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Striate Body><Striatum><Study Type><Subcellular Process><T2 DM><T2D><T2DM><Testing><Therapeutic Hormone><Thesaurismosis><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Tyr-Tyr><Weight Gain><Weight Increase><Work><Youth><Youth 10-21><adiposity><adolescence (12-20)><adult onset diabetes><adulthood><age 7><age 7 years><behavior influence><behavioral influence><biological signal transduction><body weight gain><body weight increase><brain pathway><brain visualization><caloric dietary content><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><critical period><cue reactivity><developmental><developmental plasticity><diabetes><diabetes risk><diets><eating cues><exposed in utero><fetal exposure><food cues><gastric inhibitory polypeptide receptor><ghrelin><glucagon-like peptide 1><glucose metabolism><glucose-dependent insulinotropic polypeptide receptor><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><hippocampal><hormonal secretion><hunger cues><hypothalamic><in utero exposure><insight><insulin resistant><insulin tolerance><intergenerational><intra-uterine environmental exposure><intrauterine environmental exposure><ketosis resistant diabetes><kids><life-style data><life-style factor><lifestyle data><lifestyle factors><long-term study><longitudinal outcome studies><longitudinal research study><maturity onset diabetes><metabolism disorder><modifiable lifestyle factors><neural><neural imaging><neural mechanism><neuro-imaging><neuroimaging><neurological imaging><neuromechanism><novel><obese children><obesity during childhood><obesity in children><obesity prevention><obesity risk><offspring><pathophysiology><pathway><pediatric><pediatric obesity><peptide tyrosine-tyrosine><precision medicine><precision-based medicine><pregnancy diabetes><prenatal><prenatal exposure><prenatal influence><prenatally exposed><prepregnancy><prevent obesity><recruit><response><risk for obesity><risk of obesity><satiety><seven year old><seven years of age><social role><striatal><study design><type 2 DM><type II DM><type two diabetes><tyrosyltyrosine><unborn><wt gain><youngster><youth age><β-cell><β-cells><βCell><♀>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ANNY H XIANG

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$845,922

FY 2026

Project Title

The Role of Gut-Brain Pathways on Childhood Obesity and Type 2 Diabetes Development

Grant Number:

1R01DK145940-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Childhood obesity and youth-onset type 2 diabetes (T2D) are increasing at an alarming rate, yet the underlying mechanisms remain poorly understood. Gut-derived hormones, including glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), peptide YY...

Research Terms

<0-11 years old><12-20 years old><21+ years old><7 year old><7 years of age><Address><Adolescence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Ammon Horn><Appetite><Appetite Regulation><BMI><BMI percentile><BMI z-score><Beta Cell><Body mass index><Brain><Brain Nervous System><Brain imaging><Brain region><Caloric Intake><Caring><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cellular Function><Cellular Physiology><Cellular Process><Central Lobe><Child><Child Youth><Childhood><Children (0-21)><Cornu Ammonis><Corpus Striatum><Corpus striatum structure><D-Glucose><Data><Desire for food><Development><Dextrose><Diabetes Mellitus><Diet><Dysfunction><Early Intervention><Encephalon><Endocrine Gland Secretion><Energy Intake><Exposure to><Female><Foundations><Functional disorder><Funding><GIP receptor><GLP-1><Gestational Diabetes><Gestational Diabetes Mellitus><Glp-1><Glucose><Glucose-Dependent Insulinotropic Polypeptide><Goals><Health><Hippocampus><Hormone secretion><Hormones><Hypothalamic structure><Hypothalamus><Impairment><Insula><Insula of Reil><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intervention><Intracellular Communication and Signaling><Island of Reil><Ketosis-Resistant Diabetes Mellitus><L-tyrosyl-L-tyrosine><Life Style><Lifestyle><Link><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Maturity-Onset Diabetes Mellitus><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Modeling><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrient><OGTT><Obesity><Oral><Oral Glucose Tolerance Test><Outcome><PYY Peptide><Participant><Pathway interactions><Peptide YY><Physical activity><Physiopathology><Play><Pregnancy-Induced Diabetes><Process><Quetelet index><Research><Research Design><Rewards><Risk><Risk Factors><Role><Satiation><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Striate Body><Striatum><Study Type><Subcellular Process><T2 DM><T2D><T2DM><Testing><Therapeutic Hormone><Thesaurismosis><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Tyr-Tyr><Weight Gain><Weight Increase><Work><Youth><Youth 10-21><adiposity><adolescence (12-20)><adult onset diabetes><adulthood><age 7><age 7 years><behavior influence><behavioral influence><biological signal transduction><body weight gain><body weight increase><brain pathway><brain visualization><caloric dietary content><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><critical period><cue reactivity><developmental><developmental plasticity><diabetes><diabetes risk><diets><eating cues><exposed in utero><fetal exposure><food cues><gastric inhibitory polypeptide receptor><ghrelin><glucagon-like peptide 1><glucose metabolism><glucose-dependent insulinotropic polypeptide receptor><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><hippocampal><hormonal secretion><hunger cues><hypothalamic><in utero exposure><insight><insulin resistant><insulin tolerance><intergenerational><intra-uterine environmental exposure><intrauterine environmental exposure><ketosis resistant diabetes><kids><life-style data><life-style factor><lifestyle data><lifestyle factors><long-term study><longitudinal outcome studies><longitudinal research study><maturity onset diabetes><metabolism disorder><modifiable lifestyle factors><neural><neural imaging><neural mechanism><neuro-imaging><neuroimaging><neurological imaging><neuromechanism><novel><obese children><obesity during childhood><obesity in children><obesity prevention><obesity risk><offspring><pathophysiology><pathway><pediatric><pediatric obesity><peptide tyrosine-tyrosine><precision medicine><precision-based medicine><pregnancy diabetes><prenatal><prenatal exposure><prenatal influence><prenatally exposed><prepregnancy><prevent obesity><recruit><response><risk for obesity><risk of obesity><satiety><seven year old><seven years of age><social role><striatal><study design><type 2 DM><type II DM><type two diabetes><tyrosyltyrosine><unborn><wt gain><youngster><youth age><β-cell><β-cells><βCell><♀>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

STEPHEN ROBERT FARMER

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$817,498

FY 2026

Project Title

Vasculature and Beige Remodeling of Obese Adipose Tissue

Grant Number:

1R01DK143245-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/18/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Adipose tissue (AT) remodeling plays a key role in metabolic homeostasis and healthy expansion of AT is required to preserve insulin sensitivity. Pathological consequences of dysfunctional AT remodeling include chronic inflammation and fibrosis that contribute to the adverse outcomes of obesity. Bei...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Katrin Jennifer Svensson

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$782,886

FY 2026

Project Title

Control of obesity by an appetite-suppressing peptide

Grant Number:

1R01DK142416-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/18/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY There is an urgent need for new therapies for metabolic disorders, including obesity, which is associated with a significant decrease in life expectancy by 5–10 years and increased mortality resulting from diabetes and cardiovascular diseases. Peptide hormones comprise a class of small (<100...

Research Terms

<3'5'-cyclic ester of AMP><ATRA><Acute><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Amino Acids><Anxiety><Appetite><Area><Autoregulation><Binding><Biochemical><Biological><Biological Function><Biological Process><Biology><Blood Glucose><Blood Sugar><Body Weight><Brain><Brain Nervous System><CREB><CREB1><CREB1 gene><Cardiovascular Diseases><Causality><Cell Body><Cell Communication and Signaling><Cell Line><Cell Nucleus><Cell Signaling><CellLine><Cells><Cerebrospinal Fluid><Collaborations><Cyclic AMP><D-Glucose><Data><Defect><Desire for food><Dextrose><Diabetes Mellitus><Dose><Eating><Encephalon><Energy Expenditure><Energy Metabolism><Etiology><Feeding behaviors><Food Intake><Food Intake Regulation><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G-Protein-Coupled Receptors><GPCR><Gene Transcription><Genetic><Genetic Transcription><Glucose><Grant><Health><Homeostasis><Human><Humulin R><Hypothalamic structure><Hypothalamus><Ingestive Behavior><Insulin><Intracellular Communication and Signaling><KO mice><Knock-out Mice><Knockout Mice><Life Expectancy><Ligands><Link><Locomotor Activity><Maps><Mediating><Mental Depression><Metabolic><Metabolic Control><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Methodology><Methods><Mice><Mice Mammals><Modern Man><Molecular Interaction><Motor Activity><Murine><Mus><Names><Nerve Cells><Nerve Unit><Neural Cell><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurocyte><Neurons><Novolin R><Nucleus><Null Mouse><Nutrient><Obesity><Organism-Level Process><Organismal Process><Orphan><Pathway interactions><Peptide Fragments><Peptide Hormone Gene><Peptide Library><Peptide Signal Sequences><Peptides><Physiologic><Physiologic Processes><Physiological><Physiological Homeostasis><Physiological Processes><Production><Protein Precursors><Proteins><Proteolytic Clipping><Proteolytic Processing><RNA Expression><Receptor Protein><Regular Insulin><Regulation><Resistance><Retinoic Acid><Saccharose><Signal Pathway><Signal Peptide><Signal Sequences><Signal Transduction><Signal Transduction Systems><Signaling><Site><Strains Cell Lines><Structure-Activity Relationship><Sucrose><Testing><Thesaurismosis><Trans Vitamin A Acid><Transcription><Tretinoin><Tretinoinum><Universities><Vitamin A Acid><Water Intake><Water consumption><adenosine 3'5' monophosphate><adiposity><all-trans-Retinoic Acid><all-trans-Vitamin A acid><aminoacid><biologic><biological signal transduction><cAMP><cAMP Response Element-Binding Protein 1><cardiovascular disorder><causation><cell type><cellular targeting><cerebral spinal fluid><chemical structure function><combat><corpulence><cultured cell line><depression><diabetes><disease causation><experiment><experimental research><experimental study><experiments><feeding><feeding-related behaviors><hypothalamic><in vitro Model><in vivo><innovate><innovation><innovative><intraperitoneal><metabolism disorder><mortality><mutant><name><named><naming><nano-molar><nanomolar><neural><neuronal><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><nutrient intake activity><pathway><peptide hormone><preference><prohormone><protein signal sequence><receptor><resistant><response><screening><screenings><spinal fluid><structure function relationship><tool><trans-Retinoic Acid>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ZHENQI LIU

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$782,459

FY 2026

Project Title

Impact of obesity on microvascular insulin action and cardiorespiratory fitness in Type 1 Diabetes

Grant Number:

1R01DK141617-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract The overall relative risk of cardiovascular disease (CVD) remains 3- to 10-fold higher in individuals with type 1 diabetes (T1D), despite intensive glycemic control and traditional CVD risk management. Epidemiologic studies indicate that more than 60% of individuals with T1D...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jun Hua

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$778,400

FY 2026

Project Title

Dysfunction of brain microvascular and lymphatic vessels in obesity-linked cognitive impairment

Grant Number:

5R01AG089247-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2025

End Date:

2/28/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Cognitive impairment is a common symptom in aging and associated neurological disorders such as Alzheimer’s disease (AD) and dementia, significantly reducing quality of life and causing a heavy burden on our health care system and society in general. Associations between obesity and impaired cogniti...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

WANLI W SMITH

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$778,400

FY 2026

Project Title

Dysfunction of brain microvascular and lymphatic vessels in obesity-linked cognitive impairment

Grant Number:

5R01AG089247-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2025

End Date:

2/28/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Cognitive impairment is a common symptom in aging and associated neurological disorders such as Alzheimer’s disease (AD) and dementia, significantly reducing quality of life and causing a heavy burden on our health care system and society in general. Associations between obesity and impaired cogniti...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Aaron S Kelly

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$759,944

FY 2026

Project Title

A Biologically Based Approach to Prevent Obesity in Older Adolescents and Young Adults

Grant Number:

1R01DK142604-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/6/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Once obesity develops and becomes entrenched, achieving sustained weight loss is extremely difficult. Thus, preventing the accumulation of excess adiposity in high-risk individuals is the ideal course of action. Adolescents/young adults (AYAs) are high-risk individuals, as this is a life st...

Research Terms

<2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate><21+ years old><Acceleration><Address><Adipose tissue><Adolescent><Adolescent Youth><Adolescent and Young Adult><Adult><Adult Human><Appetite><Appetite stimulated><Approaches to prevention><Automobile Driving><BMI><BMI percentile><BMI z-score><Basal Metabolism><Basal metabolic rate><Behavior><Biological><Biological Function><Biological Process><Body Weight><Body Weight decreased><Body fat><Body mass index><Calories><Classification><Clinical Trials><Consumption><Controlled Clinical Trials><Counseling><Desire for food><Dietary quality><Dose><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drops><Drug Therapy><Drugs><Dysfunction><Early identification><Eating Behavior><Eating Disorders><Energy Expenditure><Energy Metabolism><Failure><Family Medical History><Family Medical History Epidemiology><Family history of><Fatty Tissue><Food><Functional disorder><Incidence><Increased food appetite><Individual><Life><Life Style><Lifestyle><Medical><Medication><Morbid Obesity><Obesity><Oral><Organism-Level Process><Organismal Process><Overweight><Parents><Participant><Pathway interactions><Pharmaceutical Preparations><Pharmacological Treatment><Pharmacotherapy><Phentermine><Physiologic><Physiologic Processes><Physiological><Physiological Processes><Physiology><Physiopathology><Placebo Control><Placebos><Predisposition><Preventative intervention><Prevention><Prevention approach><Preventive><Quetelet index><Randomized><Regulation><Reporting><Risk><Risk Factors><Route><Satiation><Science><Severe obesity><Sham Treatment><Susceptibility><System><Systematics><Time><Visceral><Visceral fat><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><adipose><adiposity><adult youth><adulthood><alpha,alpha-dimethyl-benzeneethanamine><biologic><body weight gain><body weight increase><body weight loss><calorie><cardiometabolic risk><compare cost><corpulence><cost comparison><cost effective><craving><diet quality><driving><drug intervention><drug treatment><drug/agent><excessive weight gain><experience><extreme obesity><extreme weight gain><flexibility><flexible><high risk><high risk group><high risk individual><high risk people><high risk population><improved><increased appetite><increased hunger><intervention for prevention><juvenile><juvenile human><obesity prevention><parent><pathophysiology><pathway><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><placebo controlled><placebo group><prevent><prevent obesity><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary end point><primary endpoint><randomisation><randomization><randomly assigned><resting metabolic rate><risk minimization><satiety><serious weight gain><severe weight gain><sham group><sham therapy><symptomatology><topiramate><weight gain prevention><weights><white adipose tissue><wt gain><wt-loss><yellow adipose tissue><young adult><young adult age><young adulthood>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David J Fulton

AUGUSTA UNIVERSITY, AUGUSTA, GA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$751,582

FY 2026

Project Title

Skeletal Muscle Health Protects Vascular Function in Obesity

Grant Number:

5R01HL176793-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity remains the most persistent threat to cardiovascular health in the United States. Exercise mitigates much of this risk, but the therapeutic benefits of exercise are frequently beyond the capabilities of the aged, the very obese or those with prior injuries. Understanding the...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David W Stepp

AUGUSTA UNIVERSITY, AUGUSTA, GA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$751,582

FY 2026

Project Title

Skeletal Muscle Health Protects Vascular Function in Obesity

Grant Number:

5R01HL176793-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity remains the most persistent threat to cardiovascular health in the United States. Exercise mitigates much of this risk, but the therapeutic benefits of exercise are frequently beyond the capabilities of the aged, the very obese or those with prior injuries. Understanding the...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Roscoe O. Brady

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$746,926

FY 2026

Project Title

Validation of a novel cerebellar-striatal satiety circuit in human

Grant Number:

5R01DK137856-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT The goal of this project is to test the hypothesis that a cerebellar-striatal circuit regulates satiety in humans. Obesity currently affects 42% of U.S. adults, with projections that by 2030, 50% of U.S. adults will have obesity. These trends forecast a parallel increase in risk of obesity-...

Research Terms

<21+ years old><Acute><Adult><Adult Human><Affect><Animal Feed><Animal Model><Animal Models and Related Studies><Animals><Appetite><Appetitive Behavior><Attention><Attenuated><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Biological><Body mass index><Brain><Brain Nervous System><Brain region><Cerebellar Cortex><Cerebellum><Clinical Trials><Complex><Corpus Striatum><Corpus striatum structure><Data><Desire for food><Development><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Eating><Encephalon><Fasting><Feeding behaviors><Food><Food Deprivation><Food Intake><Food deprivation (experimental)><Functional MRI><Functional Magnetic Resonance Imaging><Future><Goals><H2O syndrome><Human><Human Characteristics><Human Nature><Hypothalamic structure><Hypothalamus><Individual><Ingestive Behavior><Intake><Intervention><Labhart-Willi Syndrome><Labhart-Willi-Prader-Fanconi Syndrome><Link><Measures><Mental Depression><Mice><Mice Mammals><Modern Man><Morbidity><Murine><Mus><Neurobiology><Neurosciences><Obesity><Participant><Pathway interactions><Population><Prader-Labhart-Willi (PLW) syndrome><Prader-Labhart-Willi syndrome><Prader-Labhart-Willi-Fanconi syndrome><Prader-Willi Syndrome><Prader-Willi syndrome (PWS)><Preclinical data><Prevalence><Protocol><Protocols documentation><Public Health><Quetelet index><Randomized><Regulation><Rewards><Role><Satiation><Satiety Response><Severities><Source><Specificity><Striate Body><Striatum><Symptoms><System><Task Performances><Techniques><Testing><Therapeutic><Therapeutic Intervention><Time><Transcranial magnetic stimulation><Translating><Translations><Validation><Ventral Striatum><addiction><addictive disorder><adiposity><adulthood><advanced system><alleviate symptom><ameliorating symptom><animal data><animal food><attenuate><attenuates><attenuation><behavior measurement><behavior response><behavioral measure><behavioral measurement><behavioral response><biologic><blood oxygen level dependent><blood oxygenation level dependent><brain behavior><brain circuitry><cardiorespiratory syndrome of obesity in child><computerized><corpulence><craving><decrease symptom><depression><deprived of food><design><designing><developmental><eating cues><effective therapy><effective treatment><experiment><experimental research><experimental study><experiments><fMRI><fasted><fasts><feeding-related behaviors><fewer symptoms><food Ingestion><food consumption><food craving><food cues><healthy weight><human data><hunger cues><hypogenital dystrophy with diabetic tendency syndrome><hypothalamic><hypotonia-hypogonadism-obesity syndrome><hypotonia-hypopigmentia-hypogonadism-obesity (HHHO) syndrome><hypotonia-hypopigmentia-hypogonadism-obesity syndrome><hypotonia-obesity-hypogonadism-mental retardation syndrome><innovate><innovation><innovative><insight><intervention therapy><model of animal><mortality><network dysfunction><neural><neural circuit><neural circuitry><neural control><neural imaging><neural regulation><neuro-imaging><neurobehavioral><neurobiological><neurocircuitry><neuroimaging><neurological imaging><neuromodulation><neuromodulatory><neuropsychiatric><neuropsychiatry><neuroregulation><novel><nutrient intake activity><obesity development><obesity intervention><obesity risk><obesity therapy><obesity treatment><pathway><patient population><preclinical findings><preclinical information><randomisation><randomization><randomly assigned><reduce symptoms><relieves symptoms><response><risk for obesity><risk of obesity><satiety><social role><striatal><success><symptom alleviation><symptom reduction><symptom relief><synaptic circuit><synaptic circuitry><therapeutic target><tool><translation><translation strategy><translational approach><translational strategy><trend><validations>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LAURA McGrath HOLSEN

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$746,926

FY 2026

Project Title

Validation of a novel cerebellar-striatal satiety circuit in human

Grant Number:

5R01DK137856-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT The goal of this project is to test the hypothesis that a cerebellar-striatal circuit regulates satiety in humans. Obesity currently affects 42% of U.S. adults, with projections that by 2030, 50% of U.S. adults will have obesity. These trends forecast a parallel increase in risk of obesity-...

Research Terms

<21+ years old><Acute><Adult><Adult Human><Affect><Animal Feed><Animal Model><Animal Models and Related Studies><Animals><Appetite><Appetitive Behavior><Attention><Attenuated><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Biological><Body mass index><Brain><Brain Nervous System><Brain region><Cerebellar Cortex><Cerebellum><Clinical Trials><Complex><Corpus Striatum><Corpus striatum structure><Data><Desire for food><Development><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Eating><Encephalon><Fasting><Feeding behaviors><Food><Food Deprivation><Food Intake><Food deprivation (experimental)><Functional MRI><Functional Magnetic Resonance Imaging><Future><Goals><H2O syndrome><Human><Human Characteristics><Human Nature><Hypothalamic structure><Hypothalamus><Individual><Ingestive Behavior><Intake><Intervention><Labhart-Willi Syndrome><Labhart-Willi-Prader-Fanconi Syndrome><Link><Measures><Mental Depression><Mice><Mice Mammals><Modern Man><Morbidity><Murine><Mus><Neurobiology><Neurosciences><Obesity><Participant><Pathway interactions><Population><Prader-Labhart-Willi (PLW) syndrome><Prader-Labhart-Willi syndrome><Prader-Labhart-Willi-Fanconi syndrome><Prader-Willi Syndrome><Prader-Willi syndrome (PWS)><Preclinical data><Prevalence><Protocol><Protocols documentation><Public Health><Quetelet index><Randomized><Regulation><Rewards><Role><Satiation><Satiety Response><Severities><Source><Specificity><Striate Body><Striatum><Symptoms><System><Task Performances><Techniques><Testing><Therapeutic><Therapeutic Intervention><Time><Transcranial magnetic stimulation><Translating><Translations><Validation><Ventral Striatum><addiction><addictive disorder><adiposity><adulthood><advanced system><alleviate symptom><ameliorating symptom><animal data><animal food><attenuate><attenuates><attenuation><behavior measurement><behavior response><behavioral measure><behavioral measurement><behavioral response><biologic><blood oxygen level dependent><blood oxygenation level dependent><brain behavior><brain circuitry><cardiorespiratory syndrome of obesity in child><computerized><corpulence><craving><decrease symptom><depression><deprived of food><design><designing><developmental><eating cues><effective therapy><effective treatment><experiment><experimental research><experimental study><experiments><fMRI><fasted><fasts><feeding-related behaviors><fewer symptoms><food Ingestion><food consumption><food craving><food cues><healthy weight><human data><hunger cues><hypogenital dystrophy with diabetic tendency syndrome><hypothalamic><hypotonia-hypogonadism-obesity syndrome><hypotonia-hypopigmentia-hypogonadism-obesity (HHHO) syndrome><hypotonia-hypopigmentia-hypogonadism-obesity syndrome><hypotonia-obesity-hypogonadism-mental retardation syndrome><innovate><innovation><innovative><insight><intervention therapy><model of animal><mortality><network dysfunction><neural><neural circuit><neural circuitry><neural control><neural imaging><neural regulation><neuro-imaging><neurobehavioral><neurobiological><neurocircuitry><neuroimaging><neurological imaging><neuromodulation><neuromodulatory><neuropsychiatric><neuropsychiatry><neuroregulation><novel><nutrient intake activity><obesity development><obesity intervention><obesity risk><obesity therapy><obesity treatment><pathway><patient population><preclinical findings><preclinical information><randomisation><randomization><randomly assigned><reduce symptoms><relieves symptoms><response><risk for obesity><risk of obesity><satiety><social role><striatal><success><symptom alleviation><symptom reduction><symptom relief><synaptic circuit><synaptic circuitry><therapeutic target><tool><translation><translation strategy><translational approach><translational strategy><trend><validations>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mark A Halko

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$746,926

FY 2026

Project Title

Validation of a novel cerebellar-striatal satiety circuit in human

Grant Number:

5R01DK137856-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT The goal of this project is to test the hypothesis that a cerebellar-striatal circuit regulates satiety in humans. Obesity currently affects 42% of U.S. adults, with projections that by 2030, 50% of U.S. adults will have obesity. These trends forecast a parallel increase in risk of obesity-...

Research Terms

<21+ years old><Acute><Adult><Adult Human><Affect><Animal Feed><Animal Model><Animal Models and Related Studies><Animals><Appetite><Appetitive Behavior><Attention><Attenuated><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Biological><Body mass index><Brain><Brain Nervous System><Brain region><Cerebellar Cortex><Cerebellum><Clinical Trials><Complex><Corpus Striatum><Corpus striatum structure><Data><Desire for food><Development><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Eating><Encephalon><Fasting><Feeding behaviors><Food><Food Deprivation><Food Intake><Food deprivation (experimental)><Functional MRI><Functional Magnetic Resonance Imaging><Future><Goals><H2O syndrome><Human><Human Characteristics><Human Nature><Hypothalamic structure><Hypothalamus><Individual><Ingestive Behavior><Intake><Intervention><Labhart-Willi Syndrome><Labhart-Willi-Prader-Fanconi Syndrome><Link><Measures><Mental Depression><Mice><Mice Mammals><Modern Man><Morbidity><Murine><Mus><Neurobiology><Neurosciences><Obesity><Participant><Pathway interactions><Population><Prader-Labhart-Willi (PLW) syndrome><Prader-Labhart-Willi syndrome><Prader-Labhart-Willi-Fanconi syndrome><Prader-Willi Syndrome><Prader-Willi syndrome (PWS)><Preclinical data><Prevalence><Protocol><Protocols documentation><Public Health><Quetelet index><Randomized><Regulation><Rewards><Role><Satiation><Satiety Response><Severities><Source><Specificity><Striate Body><Striatum><Symptoms><System><Task Performances><Techniques><Testing><Therapeutic><Therapeutic Intervention><Time><Transcranial magnetic stimulation><Translating><Translations><Validation><Ventral Striatum><addiction><addictive disorder><adiposity><adulthood><advanced system><alleviate symptom><ameliorating symptom><animal data><animal food><attenuate><attenuates><attenuation><behavior measurement><behavior response><behavioral measure><behavioral measurement><behavioral response><biologic><blood oxygen level dependent><blood oxygenation level dependent><brain behavior><brain circuitry><cardiorespiratory syndrome of obesity in child><computerized><corpulence><craving><decrease symptom><depression><deprived of food><design><designing><developmental><eating cues><effective therapy><effective treatment><experiment><experimental research><experimental study><experiments><fMRI><fasted><fasts><feeding-related behaviors><fewer symptoms><food Ingestion><food consumption><food craving><food cues><healthy weight><human data><hunger cues><hypogenital dystrophy with diabetic tendency syndrome><hypothalamic><hypotonia-hypogonadism-obesity syndrome><hypotonia-hypopigmentia-hypogonadism-obesity (HHHO) syndrome><hypotonia-hypopigmentia-hypogonadism-obesity syndrome><hypotonia-obesity-hypogonadism-mental retardation syndrome><innovate><innovation><innovative><insight><intervention therapy><model of animal><mortality><network dysfunction><neural><neural circuit><neural circuitry><neural control><neural imaging><neural regulation><neuro-imaging><neurobehavioral><neurobiological><neurocircuitry><neuroimaging><neurological imaging><neuromodulation><neuromodulatory><neuropsychiatric><neuropsychiatry><neuroregulation><novel><nutrient intake activity><obesity development><obesity intervention><obesity risk><obesity therapy><obesity treatment><pathway><patient population><preclinical findings><preclinical information><randomisation><randomization><randomly assigned><reduce symptoms><relieves symptoms><response><risk for obesity><risk of obesity><satiety><social role><striatal><success><symptom alleviation><symptom reduction><symptom relief><synaptic circuit><synaptic circuitry><therapeutic target><tool><translation><translation strategy><translational approach><translational strategy><trend><validations>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Qi Zhao

UNIVERSITY OF TENNESSEE HEALTH SCI CTR, MEMPHIS, TN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$736,009

FY 2026

Project Title

Prenatal Longitudinal Metabolomics Profiling for Early Childhood Growth Trajectories and Obesity Risk in a US Biracial Birth Cohort

Grant Number:

5R01DK134937-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Childhood obesity remains one of the most serious public health challenges because of its persistent high prevalence and adverse health consequences. There is an urgent need for novel biomarkers which can predict and provide effective interventional targets for the early prevention of childhood obes...

Research Terms

<0-11 years old><2nd trimester><3rd trimester><4 year old><4 years of age><Active Follow-up><Adult-Onset Diabetes Mellitus><Affect><African American><Afro American><Afroamerican><Alcohol Drinking><Alcohol consumption><American><Assay><Beginning of Life><Bioassay><Biological><Biological Assay><Biological Function><Biological Process><Birth><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood specimen><Body Tissues><Caloric Intake><Cardiovascular Diseases><Child><Child Youth><Childhood><Children (0-21)><Clinical><Clinical Data><Collection><Cord Blood><County><Development><Diet><Dietary Factors><Dietary Practices><Disease><Disorder><Endogenous Factors><Energy Intake><Environmental Exposure><Epidemic><EtOH drinking><EtOH use><European><Exogenous Factors><Future><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Goals><Growth><Health><High Prevalence><Individual><Intervention><Investigation><Ketosis-Resistant Diabetes Mellitus><LC/MS><Last Trimester><Learning><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Link><Live Birth><Maturity-Onset Diabetes Mellitus><Measurement><Measures><Mediation><Mendelian randomization><Methods><Midtrimester><Molecular Weight><Morbidity><Mothers><NIDDM><Negotiating><Negotiation><Neurocognitive><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obesity Epidemic><Organism-Level Process><Organismal Process><Outcome><Overweight><Participant><Parturition><Physiologic Processes><Physiological Processes><Plasma><Plasma Serum><Predicting Risk><Pregnancy><Pregnancy-Induced Diabetes><Pregnant Women><Prevention><Public Health><Race><Races><Reticuloendothelial System, Serum, Plasma><Risk Factors><Sampling><Second Pregnancy Trimester><Second Trimester><Slow-Onset Diabetes Mellitus><Smoking><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Technology><Tennessee><Testing><Third Pregnancy Trimester><Third Trimester><Time><Tissue Growth><Tissues><Translational Research><Translational Science><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Umbilical Cord><Umbilical Cord Blood><Umbilical cord structure><Validation><Visit><Weight Gain><Weight Increase><active followup><adiposity><adult adiposity><adult obesity><adult onset diabetes><adults with obesity><adverse consequence><adverse outcome><age 4><age 4 years><alcohol ingestion><alcohol intake><alcohol product use><alcohol use><alcoholic beverage consumption><alcoholic drink intake><bi-racial><biologic><biracial><body weight gain><body weight increase><caloric dietary content><cardiovascular disorder><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><developmental><dietary pattern><diets><early biomarkers><early childhood><early detection biomarkers><early detection markers><effective intervention><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol use><expectant mother><expectant women><expecting mother><expecting women><exposure to environmental agents><exposure to environmental factors><exposure to environmental stimuli><exposure to environmental substances><fast weight gain><fetal><fetal cord blood><follow up><follow-up><followed up><followup><forecasting risk><four year old><four years of age><gestational weight gain><individuals who are pregnant><innovate><innovation><innovative><insight><ketosis resistant diabetes><kids><later in life><later life><life course><life span><lifespan><liquid chromatography mass spectrometry><malleable risk><maternal condition><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><modifiable risk><new marker><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><novel biomarker><novel marker><obese children><obesity during childhood><obesity in children><obesity risk><offspring><offspring obesity><ontogeny><overweight child><overweight childhood><pediatric><pediatric obesity><people who are pregnant><personalized health intervention><personalized intervention><precision interventions><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><predictive risk><predicts risk><pregnancy diabetes><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prenatal risk factor><prepregnancy obesity><prevent><preventing><psychologic><psychological><racial><racial background><racial origin><rapid growth><rapid weight gain><recruit><risk for obesity><risk of obesity><risk prediction><risk predictions><sex><sudden weight gain><those who are pregnant><tool><translation research><translational investigation><type 2 DM><type II DM><type two diabetes><unborn><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><validations><women who are pregnant><wt gain><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

James C Lo

WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$730,588

FY 2026

Project Title

Mechanisms of Obesity-induced Atrial Fibrillation

Grant Number:

5R01HL177651-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/22/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract Atrial fibrillation (AF) is the most common sustained arrhythmia with approximately one quarter of all adults developing AF by the age of 80. AF can be symptomatic with people experiencing palpitations, racing heart, syncope, congestive heart failure, and cardioembolic stro...

Research Terms

<21+ years old><3-Pyridinecarboxamide><AF 2><AF2><ATF6><ATF6 gene><Accessory Sinuses><Activating Transcription Factor 6><Active Follow-up><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><Aging><American><American Heart Association><Apoplexy><Arrhythmia><Atrial><Atrial Fibrillation><Auricular Fibrillation><Autoregulation><Biochemical><Blood Glucose><Blood Sugar><Brain Vascular Accident><Cardiac><Cardiac Arrhythmia><Cardiac Atrium><Cardiac Failure Congestive><Cardiology><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic><Clinical><Clinical Management><Congestive Heart Failure><Cytometry><Data><Development><Diabetes Mellitus><Dihydronicotinamide Adenine Dinucleotide><Dilatation><Dilatation - action><Diphosphopyridine Nucleotide><Disease><Disorder><Dysfunction><ER stress><Epidemic><Epidemiology><Fainting><Fatty Tissue><Fibrosis><Foundations><Functional disorder><Genes><Goals><Guidelines><Health><Heart><Heart Arrhythmias><Heart Atrium><Heart Decompensation><Heart Vascular><Homeostasis><Image><Incidence><Inflammation><Intermediary Metabolism><Ion Transport><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Link><Maps><Maturity-Onset Diabetes Mellitus><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolic dysfunction><Metabolic syndrome><Metabolism><Mice><Mice Mammals><Molecular><Murine><Mus><Muscle Cells><Muscle Disease><Muscle Disorders><Muscular Diseases><Myocytes><Myopathic Conditions><Myopathic Diseases and Syndromes><Myopathic disease or syndrome><Myopathy><NIDDM><Nadide><Nasal Sinuses><Nasal cavity/Paranasal><Nasal cavity/Paranasal sinuses><Niacinamide><Nicotinamide><Nicotinamide adenine dinucleotide><Nicotinamide-Adenine Dinucleotide><Nicotinamidum><Nicotinic acid amide><Nicotylamide><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Palpitations><Paranasal Sinuses><Pathogenesis><Pathologic><Pathway interactions><Pellagra-Preventing Factor><Persons><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Population><Pre-Clinical Model><Preclinical Models><Prevalence><Proteins><Race><Races><Risk><Risk Factors><Role><SIRT1><SIRT1 gene><Severities><Sinus><Sirtuin 1><Slow-Onset Diabetes Mellitus><Societies><Stable Diabetes Mellitus><Stroke><Syncope><T2 DM><T2D><T2DM><Testing><Thesaurismosis><Transgenic Mice><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Vitamin B 3><Vitamin B3><Vitamin PP><Work><active followup><adipose><adiposity><adult onset diabetes><adulthood><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><atrium><blood glucose regulation><brain attack><cardiac metabolism><cardiac rhythm><cardiovascular disorder><cerebral vascular accident><cerebrovascular accident><chronic heart failure><circulatory system><college><collegiate><compare to control><comparison control><corpulence><developmental><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><early onset><endoplasmic reticulum stress><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><glucose control><glucose homeostasis><glucose regulation><heart metabolism><heart rhythm><imaging><insight><ketosis resistant diabetes><life-time risk><lifetime risk><man><maturity onset diabetes><metabolism disorder><metabolism measurement><metabolomics><metabonomics><mouse model><murine model><muscular disorder><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><nicotinamide ribonucleoside><nicotinamide ribose><nicotinamide riboside><nicotinamide-beta-riboside><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><older women><pathophysiology><pathway><population aging><prevent><preventing><protection pathway><protective pathway><public health relevance><racial><racial background><racial origin><renal><response><social role><stroked><strokes><synergism><transcriptomics><type 2 DM><type II DM><type two diabetes><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Iris Z Jaffe

TUFTS MEDICAL CENTER, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$729,769

FY 2026

Project Title

Smooth Muscle Mineralocorticoid Receptor in Obesity-Induced Vascular Stiffness

Grant Number:

5R01HL119290-10

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/5/2014

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity impacts 42% of US adults with greater prevalence in women. Obesity is associated with increased risk of cardiovascular (CV) disease. Elevated body mass index strongly correlates with large vessel vascular stiffness which increases cardiac work and damages small vessels, thereby also correlat...

Research Terms

<21+ years old><Actins><Adipose tissue><Adult><Adult Human><Age><Aging><Aldosterone><Aldosterone Receptor><Animal Model><Animal Models and Related Studies><Aorta><Apoplexy><Atomic Force Microscopy><Automobile Driving><Award><BMI><BMI percentile><BMI z-score><BP homeostasis><BP regulation><Basal Transcription Factor><Basal transcription factor genes><Binding><Binding Sites><Blood Pressure><Blood Vessels><Body mass index><Brain Vascular Accident><CRISPR><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas system><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cardiac><Cardiac health><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cas nuclease technology><Cell Anoxia><Cell Hypoxia><Cellular Anoxia><Cellular Hypoxia><Cellular Matrix><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><ChIP Sequencing><ChIP assay><ChIP-seq><ChIPseq><Chromatin><Clustered Regularly Interspaced Short Palindromic Repeats><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Combining Site><Confocal Microscopy><Cytoskeletal System><Cytoskeleton><Data><Diet><Differences between sexes><Differs between sexes><Drugs><Dysfunction><Elastin><FDA approved><Fats><Fatty Tissue><Fatty acid glycerol esters><Female><Fibrosis><Fibrosis in the heart><Fibrosis in the myocardium><Fibrosis within the heart><Fibrosis within the myocardium><Fibrotic myocardium><Force Microscopy><Functional disorder><Gene Action Regulation><Gene Expression><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Transcription><Genome><Goals><HIF 1 alpha><HIF-1alpha><HIF1-Alpha><HIF1A><HIF1A gene><HIF1α><Heart><Heart Hypertrophy><Heart Vascular><Heart failure><Heart health><High Fat Diet><Histology><Human><Hypertension><Immunoblotting><In Situ Hybridization><In Vitro><Inflammation><Inflammatory><Integrins><Integrins Extracellular Matrix><Involuntary Muscle><Isoforms><KO mice><Kidney><Kidney Failure><Kidney Insufficiency><Kidney Urinary System><Knock-in><Knock-out Mice><Knockout Mice><Lead><Leanness><Leiomyocyte><Lung><Lung Respiratory System><MOP1><Measurement><Measures><Mediating><Medical><Medication><Messenger RNA><Mice><Mice Mammals><Mineralocorticoid Receptor><Modern Man><Molecular><Molecular Interaction><Murine><Mus><Myocardial Infarct><Myocardial Infarction><Myocardial depression><Myocardial dysfunction><Non-Polyadenylated RNA><Null Mouse><Obesity><Organ><Outcome><Oxidative Stress><Pb element><Pharmaceutical Preparations><Physiologic pulse><Physiopathology><Population><Process><Protein Isoforms><Proteins><Publishing><Pulse><Pulse Pressure><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><Quetelet index><RNA><RNA Expression><RNA Gene Products><Race><Races><Reactive Site><Receptor Protein><Renal Failure><Renal Insufficiency><Ribonucleic Acid><Risk><Role><Scanning Force Microscopy><Sex Differences><Sexual differences><Smooth Muscle><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Stroke><Structure><Telemetries><Telemetry><Testing><Thinness><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Transcriptional Control><Transcriptional Regulation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular Smooth Muscle><Vascular aging><Weight><Western Blotting><Western Immunoblotting><Woman><Women's prevalence><Work><adipose><adiposity><adulthood><adverse consequence><adverse outcome><ages><aging associated><aging related><antagonism><antagonist><blood pressure homeostasis><blood pressure regulation><brain attack><cardiac dysfunction><cardiac failure><cardiac fibrosis><cardiac function><cardiac hypertrophy><cardiac infarct><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular effects><cardiovascular function><cardiovascular health><cerebral vascular accident><cerebrovascular accident><chromatin immunoprecipitation><chromatin immunoprecipitation coupled with sequencing><chromatin immunoprecipitation followed by sequencing><chromatin immunoprecipitation with sequencing><chromatin immunoprecipitation-seq><chromatin immunoprecipitation-sequencing><circulatory system><comparing females and males><comparing women and men><coronary attack><coronary fibrosis><coronary infarct><coronary infarction><corpulence><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><driving><drug/agent><female prevalence><females compared to males><females compared with males><females versus males><females vs. males><fibrotic heart><function of the heart><gene locus><genetic locus><genomic location><genomic locus><heart attack><heart dysfunction><heart fibrosis><heart function><heart infarct><heart infarction><heavy metal Pb><heavy metal lead><high blood pressure><high risk><human female><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><in situ Hybridization Genetics><in situ Hybridization Staining Method><in vivo><innovate><innovation><innovative><interest><intracellular skeleton><knockin><loss of function><mRNA><male><men><model of animal><mouse model><murine model><myocardial fibrosis><novel><obese individuals><obese people><obese person><obese population><obese subjects><pathophysiology><precision medicine><precision-based medicine><prevalence among females><prevalence among women><prevalence in females><prevalence in women><prevalent among females><prevalent among women><prevalent in females><prevalent in women><prevent><preventing><promoter><promotor><protein blotting><qRTPCR><racial><racial background><racial origin><receptor><receptor expression><regulate BP><regulate blood pressure><renal><response><sex><sex based differences><sex dimorphism><sex-dependent differences><sex-related differences><sex-specific differences><sexual dimorphism><sexually dimorphic><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stroked><strokes><telemetric><transcription factor><vascular><vascular inflammation><vasculature aging><weights><white adipose tissue><women compared to men><women compared with men><women versus men><women vs. men><yellow adipose tissue><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yingchang Lu

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$728,959

FY 2026

Project Title

Virtual systemic identification of drug targets of obesity candidate genes

Grant Number:

5R01DK135938-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over 40% of adults are obese in the US. Although reducing caloric intake and/or increasing physical activity can lead to weight loss in the short to medium term in some people, they lose efficacy in the long term. Bariatric surgeries are currently the most durable and effective treatment for obesity...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jonathan Mark Brown

CLEVELAND CLINIC LERNER COM-CWRU, CLEVELAND, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$728,435

FY 2026

Project Title

Gut Microbe-Derived Lipids Shape Chronic Inflammation in Cardiometabolic Disease

Grant Number:

5R01HL179780-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Recent evidence has emerged that microbes resident in the human intestine represent a key transmissible environmental factor contributing to a number of human diseases including obesity, diabetes, atherosclerotic cardiovascular disease. However, mechanisms by which gut microbial- derived fa...

Research Terms

<2-amino-1,3-propanediol><APOE><ASCVD><Active Follow-up><Address><Adipose tissue><Adult-Onset Diabetes Mellitus><Amides><Antiinflammatory Effect><Apo-E><ApoE protein><Apolipoprotein E><Assay><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Bioassay><Biological Assay><Blood><Blood Reticuloendothelial System><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><C57BL/6 Mouse><Cardiac Diseases><Cardiac Disorders><Cardiometabolic Disease><Cardiometabolic Disorder><Cell Communication and Signaling><Cell Signaling><Chronic><Chronotherapy><Circadian Dysregulation><Circulation><Clinical><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dose><Drug Targeting><Endocrine Gland Secretion><Endocrinology><Environmental Factor><Environmental Risk Factor><Enzyme Gene><Enzymes><Fats><Fatty Tissue><Fatty acid glycerol esters><Foam Cells><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G-Protein-Coupled Receptors><GI microbiome><GPCR><GPR119><GPR119 receptor><Genes><Gnotobiotic><Gnotobiotics><Goals><Heart Diseases><Heart failure><High Fat Diet><Hormonal><Hormones><Human><Humulin R><Inflammasome><Inflammation><Inflammatory><Inflammatory Response><Innate Immune Response><Insulin><Insulin Resistance><Intermediary Metabolism><Intestinal><Intestines><Intracellular Communication and Signaling><Isotopes><Jet Lag><Jet Lag Syndrome><Jetlag><Jetlag Syndrome><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out Mice><Knockout Mice><L Cells><Leptin><Libraries><Light><Link><Lipids><MEFV gene product><Macrophage><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Metabolic><Metabolic Pathway><Metabolic Processes><Metabolism><Metabolism and Endocrinology><Methods><Mice><Mice Mammals><Microbe><Modeling><Modern Man><Molecular><Murine><Mus><Mφ><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Null Mouse><Ob Gene Product><Ob Protein><Obese Gene Product><Obese Protein><Obesity><Pathway interactions><Pattern><Pattern recognition receptor><Peripheral><Phase><Photoradiation><Pollution><Probiotics><Production><Proteins><Receptor Cross-Talk><Receptor Protein><Regular Insulin><Sampling><Shapes><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Sterols><System><T2 DM><T2D><T2DM><Testing><Therapeutic><Therapeutic Hormone><Time Zone Change Syndrome><Time Zone Syndrome><Tissues><Transplantation><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><active followup><adipose><adiposity><adult onset diabetes><anti-inflammatory effect><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><bacteria in the gut><biological signal transduction><bowel><cardiac failure><circadian abnormality><circadian clock><circadian disruption><circadian disturbance><circadian dysfunction><circadian impairment><circadian pacemaker><commensal bacteria><commensal bacterial species><corpulence><cytokine><day shift><developmental><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><digestive tract microbiome><disease phenotype><enteric microbiome><environmental risk><experiment><experimental research><experimental study><experiments><fecal sample><follow up><follow-up><followed up><followup><gain of function><gastrointestinal microbiome><gut bacteria><gut microbes><gut microbial species><gut microbiome><gut-associated microbiome><heart disorder><host microbiota><host microflora><human disease><improved><in vivo><innovate><innovation><innovative><insulin resistant><insulin tolerance><intestinal biome><intestinal microbes><intestinal microbiome><ketosis resistant diabetes><marenostrin><maturity onset diabetes><microbial><microbiome community><mouse model><murine model><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><night shift><night work><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><overexpress><overexpression><pathway><pre-clinical><preclinical><prevent><preventing><probiotic therapeutic><probiotic therapy><probiotic treatment><public health relevance><pyrin><receptor><resident microbes><resident microflora><serinol><shift work><shiftwork><stool sample><stool specimen><transplant><type 2 DM><type II DM><type two diabetes><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrea E Cassidy-Bushrow

MICHIGAN STATE UNIVERSITY, EAST LANSING, MI

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$727,383

FY 2026

Project Title

A Pre-, Peri-, and Post-natal Approach to Understanding the Risk and Mechanisms for Obesity

Grant Number:

5R01DK135054-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Although obesity is a serious threat to the nation’s health, little progress has been made in its prevention. Infancy may be an opportune time to prevent its development since the sooner the trajectory towards obesity is halted, the less likely that negative health consequences will ...

Research Terms

<0-11 years old><1 year of age><1 year old><2 year old><2 years of age><Acceleration><Adipose tissue><Affect><Age Months><Alimentary Canal><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Antimicrobial Resistance><BMI><BMI percentile><BMI z-score><Bacteria><Biochemical Pathway><Bioinformatics><Biological><Birth><Blood Glucose><Blood Pressure><Blood Sugar><Body Size><Body mass index><Caloric Intake><Categories><Causality><Child><Child Youth><Children (0-21)><Communities><Data><Data Set><Deposit><Deposition><Development><Diet><Digestive Tract><Dimensions><Energy Intake><Energy harvesting><Enrollment><Environment><Etiology><Exclusion><Fatty Tissue><Feces><Future><GI Tract><GI microbiota><Gastrointestinal Tract><Gastrointestinal microbiota><Gastrointestinal tract structure><Gene Expression><Generalized Growth><Gestation><Growth><Health><Infant><Intervention><Intervention Strategies><Knowledge><Life><Maternal Nutrition><Maternal diet><Measures><Medical Records><Meta-Analysis><Metabolic><Metabolic Networks><Methods><Michigan><Microbe><Miscellaneous Antibiotic><Mothers><Obesity><Obesity Epidemic><Overweight><Parturition><Pathogenicity><Pathway interactions><Perinatal><Peripartum><Phenotype><Pregnancy><Prevention><Public Health><Quetelet index><Recommendation><Research><Risk><Risk Factors><Sampling><Shotguns><Subgroup><Testing><Time><Tissue Growth><Underweight><Unplanned pregnancy><Weight><Weight Gain><Weight Increase><Woman><adipose><adiposity><age 1><age 1 year><age 2><age 2 years><aged 1 year><aged 2 years><aged one year><aged two years><alimentary tract><anti-microbial><anti-microbial resistant><antimicrobial><bacterial community><before conception><biologic><blood pressure elevation><body weight gain><body weight increase><caloric dietary content><cardiometabolic><cardiometabolism><causal diagram><causal model><causation><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><combat><corpulence><developmental><dietary><diets><digestive canal><disease causation><effective intervention><elevated blood pressure><enroll><enteric microbial community><enteric microbiota><experiment><experimental research><experimental study><experiments><falls><fasting blood glucose level><fecal sample><gastrointestinal><gastrointestinal microbial flora><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiota><gut microbiotic><gut microflora><increase in blood pressure><increased blood pressure><infancy><infantile><intestinal flora><intestinal microbiota><intestinal microflora><intestinal tract microflora><kids><later in life><later life><maternal adiposity><maternal nutrition during pregnancy><maternal obesity><maternal weight><member><metabolic phenotype><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><metabotype><metagenome sequencing><metagenomic sequencing><microbial><microbiota composition><mother nutrition><obese children><obesity during childhood><obesity in children><obesity prevention><obesity risk><offspring><offspring obesity><one year of age><one year old><ontogeny><pathway><pediatric obesity><postnatal><preconception><prenatal><prepregnancy><prepregnancy obesity><prevent><prevent obesity><preventing><prior to conception><prospective><recruit><resistance gene><resistance locus><resistance to anti-microbial><resistant gene><resistant to antimicrobial><risk for obesity><risk of obesity><shot gun><stool><stool sample><stool specimen><two year old><two years of age><unborn><unintended pregnancy><urinary><weights><white adipose tissue><wt gain><yellow adipose tissue><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sarah S. Comstock

MICHIGAN STATE UNIVERSITY, EAST LANSING, MI

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$727,383

FY 2026

Project Title

A Pre-, Peri-, and Post-natal Approach to Understanding the Risk and Mechanisms for Obesity

Grant Number:

5R01DK135054-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Although obesity is a serious threat to the nation’s health, little progress has been made in its prevention. Infancy may be an opportune time to prevent its development since the sooner the trajectory towards obesity is halted, the less likely that negative health consequences will ...

Research Terms

<0-11 years old><1 year of age><1 year old><2 year old><2 years of age><Acceleration><Adipose tissue><Affect><Age Months><Alimentary Canal><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Antimicrobial Resistance><BMI><BMI percentile><BMI z-score><Bacteria><Biochemical Pathway><Bioinformatics><Biological><Birth><Blood Glucose><Blood Pressure><Blood Sugar><Body Size><Body mass index><Caloric Intake><Categories><Causality><Child><Child Youth><Children (0-21)><Communities><Data><Data Set><Deposit><Deposition><Development><Diet><Digestive Tract><Dimensions><Energy Intake><Energy harvesting><Enrollment><Environment><Etiology><Exclusion><Fatty Tissue><Feces><Future><GI Tract><GI microbiota><Gastrointestinal Tract><Gastrointestinal microbiota><Gastrointestinal tract structure><Gene Expression><Generalized Growth><Gestation><Growth><Health><Infant><Intervention><Intervention Strategies><Knowledge><Life><Maternal Nutrition><Maternal diet><Measures><Medical Records><Meta-Analysis><Metabolic><Metabolic Networks><Methods><Michigan><Microbe><Miscellaneous Antibiotic><Mothers><Obesity><Obesity Epidemic><Overweight><Parturition><Pathogenicity><Pathway interactions><Perinatal><Peripartum><Phenotype><Pregnancy><Prevention><Public Health><Quetelet index><Recommendation><Research><Risk><Risk Factors><Sampling><Shotguns><Subgroup><Testing><Time><Tissue Growth><Underweight><Unplanned pregnancy><Weight><Weight Gain><Weight Increase><Woman><adipose><adiposity><age 1><age 1 year><age 2><age 2 years><aged 1 year><aged 2 years><aged one year><aged two years><alimentary tract><anti-microbial><anti-microbial resistant><antimicrobial><bacterial community><before conception><biologic><blood pressure elevation><body weight gain><body weight increase><caloric dietary content><cardiometabolic><cardiometabolism><causal diagram><causal model><causation><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><combat><corpulence><developmental><dietary><diets><digestive canal><disease causation><effective intervention><elevated blood pressure><enroll><enteric microbial community><enteric microbiota><experiment><experimental research><experimental study><experiments><falls><fasting blood glucose level><fecal sample><gastrointestinal><gastrointestinal microbial flora><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiota><gut microbiotic><gut microflora><increase in blood pressure><increased blood pressure><infancy><infantile><intestinal flora><intestinal microbiota><intestinal microflora><intestinal tract microflora><kids><later in life><later life><maternal adiposity><maternal nutrition during pregnancy><maternal obesity><maternal weight><member><metabolic phenotype><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><metabotype><metagenome sequencing><metagenomic sequencing><microbial><microbiota composition><mother nutrition><obese children><obesity during childhood><obesity in children><obesity prevention><obesity risk><offspring><offspring obesity><one year of age><one year old><ontogeny><pathway><pediatric obesity><postnatal><preconception><prenatal><prepregnancy><prepregnancy obesity><prevent><prevent obesity><preventing><prior to conception><prospective><recruit><resistance gene><resistance locus><resistance to anti-microbial><resistant gene><resistant to antimicrobial><risk for obesity><risk of obesity><shot gun><stool><stool sample><stool specimen><two year old><two years of age><unborn><unintended pregnancy><urinary><weights><white adipose tissue><wt gain><yellow adipose tissue><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JUDITH K OCKENE

UNIV OF MASSACHUSETTS MED SCH WORCESTER, WORCESTER, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$723,065

FY 2026

Project Title

MRWeight: Medical Residents Learning Weight Management Counseling Skills -- A Multi-Modal, Technology-Assisted, Spaced Education Program

Grant Number:

5R01DK134372-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/2/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

7. Project Summary/Abstract Overweight and obesity have reached epidemic proportions in the United States, proving to be a very difficult health challenge for both patients and the physicians who care for them. Excess weight is a major contributor to heart disease, stroke, and type 2 diabetes. Addre...

Research Terms

<21+ years old><Active Follow-up><Address><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Advocate><Affect><American><American Heart Association><Apoplexy><Assessment instrument><Assessment tool><Behavior><Brain Vascular Accident><Cardiac Diseases><Cardiac Disorders><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Chronic Disease><Chronic Illness><Clinical><Communication><Comparison arm><Complex><Counseling><Curriculum><Diet><Dissemination and Implementation><E-Mail><Education><Educational Curriculum><Educational aspects><Educational process of instructing><Effectiveness of Interventions><Electronic Mail><Email><Epidemic><Evaluation><Feedback><Future><Guidelines><Health><Heart Diseases><History><Intention><Internal Medicine><Intervention><Ketosis-Resistant Diabetes Mellitus><Knowledge><Learning><Matched Group><Maturity-Onset Diabetes Mellitus><Mediating><Mediator><Medical><Medical Education><Medical Examiners><Methods><NIDDM><NIH><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obesity Epidemic><Obesity associated disease><Obesity related disease><Outcome><Overweight><Patient Care><Patient Care Delivery><Patient Self-Report><Patients><Physical activity><Physicians><Pilot Projects><Play><Post Graduate Year><Primary Care><Process><Process Measure><Program Appropriateness><Psychological reinforcement><Public Health><Publishing><Randomization trial><Randomized, Controlled Trials><Recommendation><Recording of previous events><Reinforcement><Reporting><Residencies><Risk><Self-Report><Self-reflection><Site><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><T2 DM><T2D><T2DM><Teaching><Technology><Technology Assessment><Testing><Text><Time><Training><Training Programs><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><United States National Institutes of Health><Visit><Weight><Weight maintenance regimen><active followup><adiposity><adult onset diabetes><adulthood><analog><assess effectiveness><brain attack><care for patients><care of patients><caring for patients><cerebral vascular accident><cerebrovascular accident><chronic disorder><clinical implementation><clinical practice><cohort><comparator arm><compare intervention><comparison intervention><corpulence><crowd source><crowd-sourcing><crowdsource><crowdsourcing><design><designing><determine effectiveness><diets><effectiveness assessment><effectiveness evaluation><electronic communication><evaluate effectiveness><evidence base><examine effectiveness><follow up><follow-up><followed up><followup><foundational course><gateway course><heart disorder><histories><innovative technologies><intervention effect><ketosis resistant diabetes><lesson plans><maturity onset diabetes><medical college><medical schools><multi-modality><multimodality><novel><obesity intervention><obesity prevention><obesity therapy><obesity treatment><patient centered><patient oriented><pilot study><prevent obesity><primary care setting><primary care visit><programs><randomized control trial><randomized trial><response><school of medicine><sex><skill acquisition><skill development><skills><social cognitive theory><social learning theory><stroked><strokes><type 2 DM><type II DM><type two diabetes><uptake><weight control><weight management><weights>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rajani Sadasivam

UNIV OF MASSACHUSETTS MED SCH WORCESTER, WORCESTER, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$723,065

FY 2026

Project Title

MRWeight: Medical Residents Learning Weight Management Counseling Skills -- A Multi-Modal, Technology-Assisted, Spaced Education Program

Grant Number:

5R01DK134372-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/2/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

7. Project Summary/Abstract Overweight and obesity have reached epidemic proportions in the United States, proving to be a very difficult health challenge for both patients and the physicians who care for them. Excess weight is a major contributor to heart disease, stroke, and type 2 diabetes. Addre...

Research Terms

<21+ years old><Active Follow-up><Address><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Advocate><Affect><American><American Heart Association><Apoplexy><Assessment instrument><Assessment tool><Behavior><Brain Vascular Accident><Cardiac Diseases><Cardiac Disorders><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Chronic Disease><Chronic Illness><Clinical><Communication><Comparison arm><Complex><Counseling><Curriculum><Diet><Dissemination and Implementation><E-Mail><Education><Educational Curriculum><Educational aspects><Educational process of instructing><Effectiveness of Interventions><Electronic Mail><Email><Epidemic><Evaluation><Feedback><Future><Guidelines><Health><Heart Diseases><History><Intention><Internal Medicine><Intervention><Ketosis-Resistant Diabetes Mellitus><Knowledge><Learning><Matched Group><Maturity-Onset Diabetes Mellitus><Mediating><Mediator><Medical><Medical Education><Medical Examiners><Methods><NIDDM><NIH><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obesity Epidemic><Obesity associated disease><Obesity related disease><Outcome><Overweight><Patient Care><Patient Care Delivery><Patient Self-Report><Patients><Physical activity><Physicians><Pilot Projects><Play><Post Graduate Year><Primary Care><Process><Process Measure><Program Appropriateness><Psychological reinforcement><Public Health><Publishing><Randomization trial><Randomized, Controlled Trials><Recommendation><Recording of previous events><Reinforcement><Reporting><Residencies><Risk><Self-Report><Self-reflection><Site><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><T2 DM><T2D><T2DM><Teaching><Technology><Technology Assessment><Testing><Text><Time><Training><Training Programs><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><United States National Institutes of Health><Visit><Weight><Weight maintenance regimen><active followup><adiposity><adult onset diabetes><adulthood><analog><assess effectiveness><brain attack><care for patients><care of patients><caring for patients><cerebral vascular accident><cerebrovascular accident><chronic disorder><clinical implementation><clinical practice><cohort><comparator arm><compare intervention><comparison intervention><corpulence><crowd source><crowd-sourcing><crowdsource><crowdsourcing><design><designing><determine effectiveness><diets><effectiveness assessment><effectiveness evaluation><electronic communication><evaluate effectiveness><evidence base><examine effectiveness><follow up><follow-up><followed up><followup><foundational course><gateway course><heart disorder><histories><innovative technologies><intervention effect><ketosis resistant diabetes><lesson plans><maturity onset diabetes><medical college><medical schools><multi-modality><multimodality><novel><obesity intervention><obesity prevention><obesity therapy><obesity treatment><patient centered><patient oriented><pilot study><prevent obesity><primary care setting><primary care visit><programs><randomized control trial><randomized trial><response><school of medicine><sex><skill acquisition><skill development><skills><social cognitive theory><social learning theory><stroked><strokes><type 2 DM><type II DM><type two diabetes><uptake><weight control><weight management><weights>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lisa Goldman Rosas

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$713,083

FY 2026

Project Title

Effectiveness of Recipe4Health on Obesity and Cardiometabolic Health: A natural experiment

Grant Number:

5R01DK140186-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Improving food security in the US is a fundamental strategy to promoting health for all populations. Food insecurity – the lack of consistent access to sufficient quantities of healthy food – leads to nutrition-sensitive chronic conditions like obesity, diabetes, and heart disease. To address the in...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

June M Tester

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$713,083

FY 2026

Project Title

Effectiveness of Recipe4Health on Obesity and Cardiometabolic Health: A natural experiment

Grant Number:

5R01DK140186-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Improving food security in the US is a fundamental strategy to promoting health for all populations. Food insecurity – the lack of consistent access to sufficient quantities of healthy food – leads to nutrition-sensitive chronic conditions like obesity, diabetes, and heart disease. To address the in...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DARA L KRAITCHMAN

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$690,951

FY 2026

Project Title

Image-guided Bariatric Arterial Embolization (BAE) for the Treatment of Obesity

Grant Number:

5R01DK135399-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2013

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over 40% of Americans are obese, with the prevalence of obesity continuing to rise. Obesity negatively affects general health and has been attributed to an increasing incidence of diabetes, heart disease, vascular disease, joint stress, lumbar spine disorders, liver and biliary disease, and various ...

Research Terms

<90Y><Address><Affect><American><Animal Model><Animal Models and Related Studies><Animals><Appetite><Appetite stimulated><Arterial Embolization><Arteries><Attenuated><BMI><BMI percentile><BMI z-score><Bariatrics><Biliary><Blood Vessels><Body Weight decreased><Body mass index><Brain><Brain Nervous System><Cancer Treatment><Cancers><Canine Species><Canis familiaris><Cardiac Diseases><Cardiac Disorders><Catheters><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Client><Clinical><Clinical Trials><Complex><Cranial Nerve X><Cryoablation><Cryosurgery><Data><Desire for food><Diabetes Mellitus><Diameter><Disease><Disorder><Dogs><Dogs Mammals><Early-Stage Clinical Trials><Embolism><Embolization Therapy><Embolotherapy><Embolus><Encapsulated><Encephalon><Endocrine><Endocrine Gland Secretion><Equipment><Esophagogastric Junction><Family suidae><Feeling><Funding><Fundus><GLP-1><Gastric Inflammation><Gastric ulcer><Gastrins><Gastritis><Gastroesophageal Junction><Glp-1><Goals><Grant><Health><Heart Diseases><Hormonal><Hormones><Human><Hunger><Hyperthermia><Image><Imaging Device><Imaging Instrument><Imaging Procedures><Imaging Technics><Imaging Techniques><Imaging Tool><Incidence><Increased food appetite><Injury><Intervention><Intestinal><Intestines><Intracellular Communication and Signaling><Ischemia><Label><Liver><Location><Magnetism><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Medical Care Costs><Microbeads><Microfluidic Device><Microfluidic Lab-On-A-Chip><Microfluidic Microchips><Microfluidics><Microspheres><Modeling><Modern Man><Morbid Obesity><Obesity><Operative Procedures><Operative Surgical Procedures><Organ><Overweight><Pancreas><Pancreatic><Patients><Perforation><Persons><Phase 1 Clinical Trials><Phase I Clinical Trials><Pigs><Pneumogastric Nerve><Prevalence><Procedures><Production><Progress Reports><Quetelet index><Radioactive><Radioembolization><Radiolabeled><Reflux><Risk><Safety><Satiation><Serious Adverse Event><Severe Adverse Event><Severe obesity><Signal Transduction><Signal Transduction Systems><Signaling><Spinal Diseases><Spleen><Spleen Reticuloendothelial System><Stomach><Stomach Ulcer><Structure><Suidae><Surgical><Surgical Interventions><Surgical Procedure><Swine><Techniques><Tenth Cranial Nerve><Testing><Therapeutic Embolization><Therapeutic Hormone><Translating><Translations><Ulcer><Ulceration><United States><Vagus Nerve><Vagus nerve structure><Vascular Diseases><Vascular Disorder><Vascular blood supply><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Y-90><Yttrium 90><adiposity><anti-cancer therapy><appetite loss><attenuate><attenuates><bariatric surgery><biological signal transduction><blood supply><blood vessel disorder><body weight gain><body weight increase><body weight loss><bowel><cancer therapy><cancer-directed therapy><canine><canine animal model><canine model><clinical hyperthermia><clinical relevance><clinically relevant><cone-beam CT><cone-beam computed tomography><corpulence><cost><diabetes><dog model><domestic dog><embolization><esophagogastric sphincter><extreme obesity><feelings><gastric><gastric artery><gastric banding><gastric bypass surgery><gastric fundus><ghrelin><glucagon-like peptide 1><heart disorder><heat injury><hepatic body system><hepatic organ system><hyperthermia therapy><hyperthermia treatment><image guidance><image guided><image guided therapy><imaging><implantable gastric stimulation banding><improved><increased appetite><increased hunger><injuries><iron oxide nano particle><iron oxide nanoparticle><joint stress><magnetic><malignancy><medical costs><medical expenses><meter><microfluidic chip><minimally invasive><model of animal><neoplasm/cancer><new approaches><novel><novel approaches><novel strategies><novel strategy><obese patients><obesity intervention><obesity surgery><obesity therapy><obesity treatment><patients with obesity><phase I protocol><porcine><radiolabeling><radiologically labeled><reconstruction><satiety><serious adverse experience><serious adverse reaction><site targeted delivery><soft tissue><spine disorder><stomach fundus><stomach stapling><success><suid><surgery><targeted delivery><thermal injury><translation><translation to humans><tumor><vascular><vascular dysfunction><vascular supply><vasculopathy><volume CT><volume computed tomography><volumetric computed tomography><weight loss surgery><weights><wt gain><wt-loss><µfluidic>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Clifford Raabe Weiss

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$690,951

FY 2026

Project Title

Image-guided Bariatric Arterial Embolization (BAE) for the Treatment of Obesity

Grant Number:

5R01DK135399-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2013

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over 40% of Americans are obese, with the prevalence of obesity continuing to rise. Obesity negatively affects general health and has been attributed to an increasing incidence of diabetes, heart disease, vascular disease, joint stress, lumbar spine disorders, liver and biliary disease, and various ...

Research Terms

<90Y><Address><Affect><American><Animal Model><Animal Models and Related Studies><Animals><Appetite><Appetite stimulated><Arterial Embolization><Arteries><Attenuated><BMI><BMI percentile><BMI z-score><Bariatrics><Biliary><Blood Vessels><Body Weight decreased><Body mass index><Brain><Brain Nervous System><Cancer Treatment><Cancers><Canine Species><Canis familiaris><Cardiac Diseases><Cardiac Disorders><Catheters><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Client><Clinical><Clinical Trials><Complex><Cranial Nerve X><Cryoablation><Cryosurgery><Data><Desire for food><Diabetes Mellitus><Diameter><Disease><Disorder><Dogs><Dogs Mammals><Early-Stage Clinical Trials><Embolism><Embolization Therapy><Embolotherapy><Embolus><Encapsulated><Encephalon><Endocrine><Endocrine Gland Secretion><Equipment><Esophagogastric Junction><Family suidae><Feeling><Funding><Fundus><GLP-1><Gastric Inflammation><Gastric ulcer><Gastrins><Gastritis><Gastroesophageal Junction><Glp-1><Goals><Grant><Health><Heart Diseases><Hormonal><Hormones><Human><Hunger><Hyperthermia><Image><Imaging Device><Imaging Instrument><Imaging Procedures><Imaging Technics><Imaging Techniques><Imaging Tool><Incidence><Increased food appetite><Injury><Intervention><Intestinal><Intestines><Intracellular Communication and Signaling><Ischemia><Label><Liver><Location><Magnetism><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Medical Care Costs><Microbeads><Microfluidic Device><Microfluidic Lab-On-A-Chip><Microfluidic Microchips><Microfluidics><Microspheres><Modeling><Modern Man><Morbid Obesity><Obesity><Operative Procedures><Operative Surgical Procedures><Organ><Overweight><Pancreas><Pancreatic><Patients><Perforation><Persons><Phase 1 Clinical Trials><Phase I Clinical Trials><Pigs><Pneumogastric Nerve><Prevalence><Procedures><Production><Progress Reports><Quetelet index><Radioactive><Radioembolization><Radiolabeled><Reflux><Risk><Safety><Satiation><Serious Adverse Event><Severe Adverse Event><Severe obesity><Signal Transduction><Signal Transduction Systems><Signaling><Spinal Diseases><Spleen><Spleen Reticuloendothelial System><Stomach><Stomach Ulcer><Structure><Suidae><Surgical><Surgical Interventions><Surgical Procedure><Swine><Techniques><Tenth Cranial Nerve><Testing><Therapeutic Embolization><Therapeutic Hormone><Translating><Translations><Ulcer><Ulceration><United States><Vagus Nerve><Vagus nerve structure><Vascular Diseases><Vascular Disorder><Vascular blood supply><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Y-90><Yttrium 90><adiposity><anti-cancer therapy><appetite loss><attenuate><attenuates><bariatric surgery><biological signal transduction><blood supply><blood vessel disorder><body weight gain><body weight increase><body weight loss><bowel><cancer therapy><cancer-directed therapy><canine><canine animal model><canine model><clinical hyperthermia><clinical relevance><clinically relevant><cone-beam CT><cone-beam computed tomography><corpulence><cost><diabetes><dog model><domestic dog><embolization><esophagogastric sphincter><extreme obesity><feelings><gastric><gastric artery><gastric banding><gastric bypass surgery><gastric fundus><ghrelin><glucagon-like peptide 1><heart disorder><heat injury><hepatic body system><hepatic organ system><hyperthermia therapy><hyperthermia treatment><image guidance><image guided><image guided therapy><imaging><implantable gastric stimulation banding><improved><increased appetite><increased hunger><injuries><iron oxide nano particle><iron oxide nanoparticle><joint stress><magnetic><malignancy><medical costs><medical expenses><meter><microfluidic chip><minimally invasive><model of animal><neoplasm/cancer><new approaches><novel><novel approaches><novel strategies><novel strategy><obese patients><obesity intervention><obesity surgery><obesity therapy><obesity treatment><patients with obesity><phase I protocol><porcine><radiolabeling><radiologically labeled><reconstruction><satiety><serious adverse experience><serious adverse reaction><site targeted delivery><soft tissue><spine disorder><stomach fundus><stomach stapling><success><suid><surgery><targeted delivery><thermal injury><translation><translation to humans><tumor><vascular><vascular dysfunction><vascular supply><vasculopathy><volume CT><volume computed tomography><volumetric computed tomography><weight loss surgery><weights><wt gain><wt-loss><µfluidic>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Susan Carnell

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$679,560

FY 2026

Project Title

Neural and behavioral mechanisms of obesity development from infancy through childhood

Grant Number:

5R01DK136602-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity risk shows individual variation such that some children are more likely than others to gain excess weight. One potential reason is that, due to genetic and environmental factors, individuals vary in appetitive behaviors that drive food intake and weight. However, the neurode...

Research Terms

<0-11 years old><21+ years old><6-11 years old><Acceleration><Address><Adult><Adult Human><Age><Appetite><Appetitive Behavior><Behavior><Behavioral><Behavioral Mechanisms><Body Weight><Brain><Brain Nervous System><CNS Nervous System><Central Nervous System><Child><Child Youth><Childhood><Children (0-21)><Corpus Striatum><Corpus striatum structure><Data><Data Analyses><Data Analysis><Data Set><Desire for food><Development><Diet Habits><Dietary Factors><Dietary Habits><Early Intervention><Eating><Eating Behavior><Encephalon><Environmental Factor><Environmental Risk Factor><Family Research><Food><Food Intake><Foundations><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Gene variant><Genetic><Genetic predisposing factor><Gliosis><Goals><Health><Home><Hypothalamic structure><Hypothalamus><Individual><Inflammatory Response><Intake><Intervention><Lead><Life><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Mechanisms of Behavior and Behavior Change><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Methods><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Nervous System Finding><Neuraxis><Neurologic Finding><Neurological observations><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><Parents><Participant><Pathogenesis><Pattern><Pb element><Performance><Reporting><Research><Rewards><Risk Factors><Role><Striate Body><Striatum><Structure><Testing><Time><United States National Institutes of Health><Variant><Variation><Weight><Weights and Measures><Zeugmatography><adiposity><adulthood><ages><allelic variant><behavior mechanism><child adiposity><child obesity><childhood adiposity><childhood obesity><cognitive control><cohort><corpulence><cue reactivity><data interpretation><developmental><discounting><early childhood><eating habit><environmental risk><excessive weight gain><extreme weight gain><fMRI><family based research><family centered research><family focused research><family investigation><feeding><food environment><genetic risk factor><genetic variant><genomic variant><gray matter><heavy metal Pb><heavy metal lead><homes><hypothalamic><individual heterogeneity><individual variability><individual variation><infancy><infantile><inherited factor><inter-individual variability><inter-individual variation><investigate family><kids><later in life><later life><middle childhood><myelination><neural mechanism><neurobehavioral><neuromechanism><obese children><obesigenic><obesity development><obesity during childhood><obesity in children><obesity prevention><obesity risk><obesogenic><parent><pediatric><pediatric obesity><postnatal><pre-clinical research><preclinical research><prenatal><prepregnancy obesity><prevent><prevent obesity><preventing><protective factors><reward processing><risk for obesity><risk of obesity><serious weight gain><severe weight gain><social role><striatal><study family><substantia grisea><survey family><unborn><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Viren Andrew D'Sa

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$679,560

FY 2026

Project Title

Neural and behavioral mechanisms of obesity development from infancy through childhood

Grant Number:

5R01DK136602-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity risk shows individual variation such that some children are more likely than others to gain excess weight. One potential reason is that, due to genetic and environmental factors, individuals vary in appetitive behaviors that drive food intake and weight. However, the neurode...

Research Terms

<0-11 years old><21+ years old><6-11 years old><Acceleration><Address><Adult><Adult Human><Age><Appetite><Appetitive Behavior><Behavior><Behavioral><Behavioral Mechanisms><Body Weight><Brain><Brain Nervous System><CNS Nervous System><Central Nervous System><Child><Child Youth><Childhood><Children (0-21)><Corpus Striatum><Corpus striatum structure><Data><Data Analyses><Data Analysis><Data Set><Desire for food><Development><Diet Habits><Dietary Factors><Dietary Habits><Early Intervention><Eating><Eating Behavior><Encephalon><Environmental Factor><Environmental Risk Factor><Family Research><Food><Food Intake><Foundations><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Gene variant><Genetic><Genetic predisposing factor><Gliosis><Goals><Health><Home><Hypothalamic structure><Hypothalamus><Individual><Inflammatory Response><Intake><Intervention><Lead><Life><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Mechanisms of Behavior and Behavior Change><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Methods><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Nervous System Finding><Neuraxis><Neurologic Finding><Neurological observations><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><Parents><Participant><Pathogenesis><Pattern><Pb element><Performance><Reporting><Research><Rewards><Risk Factors><Role><Striate Body><Striatum><Structure><Testing><Time><United States National Institutes of Health><Variant><Variation><Weight><Weights and Measures><Zeugmatography><adiposity><adulthood><ages><allelic variant><behavior mechanism><child adiposity><child obesity><childhood adiposity><childhood obesity><cognitive control><cohort><corpulence><cue reactivity><data interpretation><developmental><discounting><early childhood><eating habit><environmental risk><excessive weight gain><extreme weight gain><fMRI><family based research><family centered research><family focused research><family investigation><feeding><food environment><genetic risk factor><genetic variant><genomic variant><gray matter><heavy metal Pb><heavy metal lead><homes><hypothalamic><individual heterogeneity><individual variability><individual variation><infancy><infantile><inherited factor><inter-individual variability><inter-individual variation><investigate family><kids><later in life><later life><middle childhood><myelination><neural mechanism><neurobehavioral><neuromechanism><obese children><obesigenic><obesity development><obesity during childhood><obesity in children><obesity prevention><obesity risk><obesogenic><parent><pediatric><pediatric obesity><postnatal><pre-clinical research><preclinical research><prenatal><prepregnancy obesity><prevent><prevent obesity><preventing><protective factors><reward processing><risk for obesity><risk of obesity><serious weight gain><severe weight gain><social role><striatal><study family><substantia grisea><survey family><unborn><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Daphne Koinis Mitchell

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$679,560

FY 2026

Project Title

Neural and behavioral mechanisms of obesity development from infancy through childhood

Grant Number:

5R01DK136602-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity risk shows individual variation such that some children are more likely than others to gain excess weight. One potential reason is that, due to genetic and environmental factors, individuals vary in appetitive behaviors that drive food intake and weight. However, the neurode...

Research Terms

<0-11 years old><21+ years old><6-11 years old><Acceleration><Address><Adult><Adult Human><Age><Appetite><Appetitive Behavior><Behavior><Behavioral><Behavioral Mechanisms><Body Weight><Brain><Brain Nervous System><CNS Nervous System><Central Nervous System><Child><Child Youth><Childhood><Children (0-21)><Corpus Striatum><Corpus striatum structure><Data><Data Analyses><Data Analysis><Data Set><Desire for food><Development><Diet Habits><Dietary Factors><Dietary Habits><Early Intervention><Eating><Eating Behavior><Encephalon><Environmental Factor><Environmental Risk Factor><Family Research><Food><Food Intake><Foundations><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Gene variant><Genetic><Genetic predisposing factor><Gliosis><Goals><Health><Home><Hypothalamic structure><Hypothalamus><Individual><Inflammatory Response><Intake><Intervention><Lead><Life><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Mechanisms of Behavior and Behavior Change><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Methods><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Nervous System Finding><Neuraxis><Neurologic Finding><Neurological observations><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><Parents><Participant><Pathogenesis><Pattern><Pb element><Performance><Reporting><Research><Rewards><Risk Factors><Role><Striate Body><Striatum><Structure><Testing><Time><United States National Institutes of Health><Variant><Variation><Weight><Weights and Measures><Zeugmatography><adiposity><adulthood><ages><allelic variant><behavior mechanism><child adiposity><child obesity><childhood adiposity><childhood obesity><cognitive control><cohort><corpulence><cue reactivity><data interpretation><developmental><discounting><early childhood><eating habit><environmental risk><excessive weight gain><extreme weight gain><fMRI><family based research><family centered research><family focused research><family investigation><feeding><food environment><genetic risk factor><genetic variant><genomic variant><gray matter><heavy metal Pb><heavy metal lead><homes><hypothalamic><individual heterogeneity><individual variability><individual variation><infancy><infantile><inherited factor><inter-individual variability><inter-individual variation><investigate family><kids><later in life><later life><middle childhood><myelination><neural mechanism><neurobehavioral><neuromechanism><obese children><obesigenic><obesity development><obesity during childhood><obesity in children><obesity prevention><obesity risk><obesogenic><parent><pediatric><pediatric obesity><postnatal><pre-clinical research><preclinical research><prenatal><prepregnancy obesity><prevent><prevent obesity><preventing><protective factors><reward processing><risk for obesity><risk of obesity><serious weight gain><severe weight gain><social role><striatal><study family><substantia grisea><survey family><unborn><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jennifer A. Emond

DARTMOUTH COLLEGE, HANOVER, NH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$673,972

FY 2026

Project Title

Characterizing the relationships of genetic risk and parental coercive feeding practices with appetitive traits and adiposity gain across early life.

Grant Number:

5R01DK136698-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY The preschool years (2-5 years of age) is a critical timeframe to shape the lifetime risk of obesity. While the causes of obesity are complex, appetitive traits related to overeating, such as high food approach and low food avoidance, are robustly associated with a greater BMI among ...

Research Terms

<0-11 years old><2 year old><2 years of age><5 year old><5 years of age><Age><Appetite><Area><BMI><BMI percentile><BMI z-score><Behavioral><Body mass index><Causality><Child><Child Rearing><Child Youth><Children (0-21)><Complex><Consumption><Data><Desire for food><Development><Dietary intake><Eating><Eating Behavior><Emotional><Emotions><Enrollment><Etiology><Exhibits><Family><Food><Food Intake><Future><Genetic><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Risk><Genetic Susceptibility><Genetic predisposing factor><Genetic propensity><Goals><Healthy Eating><Heterogeneity><Hyperphagia><Informal Social Control><Inherited Predisposition><Inherited Susceptibility><Intake><Intervention Strategies><Life><Longitudinal Studies><Longitudinal Surveys><Measurement><Measures><Mediating><Mediation><Modeling><Modification><Needs Assessment><Negotiating><Negotiation><Neurobiology><Nursery Schools><Obesity><Overeating><Parenting><Parenting behavior><Parents><Predisposition><Prevention program><Quetelet index><Research><Risk Factors><Self Regulation><Shapes><Single Base Polymorphism><Single Nucleotide Polymorphism><Stimulus><Susceptibility><Testing><Time><Work><adiposity><age 2><age 2 years><age 5><age 5 years><aged 2 years><aged two years><ages><attentional bias><causation><child adiposity><child obesity><childhood adiposity><childhood obesity><childrearing><cohort><corpulence><design><designing><developmental><disease causation><early childhood><eating in absence of hunger><enroll><eye tracking><feeding><five year old><five years of age><food avoidance><genetic risk factor><genetic vulnerability><genetically predisposed><inherited factor><kids><life-time risk><lifetime risk><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal research study><longitudinal study design><neurobiological><new approaches><novel><novel approaches><novel strategies><novel strategy><obese children><obesigenic><obesity during childhood><obesity genetics><obesity in children><obesity prevention><obesity risk><obesogenic><parent><pediatric obesity><polygenetic risk scores><polygenic risk score><polyphagia><pre-k><pre-kindergarten><preschool><prevent obesity><prospective><prospective test><response><risk for obesity><risk of obesity><single nucleotide variant><skills><theories><trait><two year old><two years of age><visual tracking><younger age><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Diane Ihn Ae Gilbert-Diamond

DARTMOUTH COLLEGE, HANOVER, NH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$673,972

FY 2026

Project Title

Characterizing the relationships of genetic risk and parental coercive feeding practices with appetitive traits and adiposity gain across early life.

Grant Number:

5R01DK136698-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY The preschool years (2-5 years of age) is a critical timeframe to shape the lifetime risk of obesity. While the causes of obesity are complex, appetitive traits related to overeating, such as high food approach and low food avoidance, are robustly associated with a greater BMI among ...

Research Terms

<0-11 years old><2 year old><2 years of age><5 year old><5 years of age><Age><Appetite><Area><BMI><BMI percentile><BMI z-score><Behavioral><Body mass index><Causality><Child><Child Rearing><Child Youth><Children (0-21)><Complex><Consumption><Data><Desire for food><Development><Dietary intake><Eating><Eating Behavior><Emotional><Emotions><Enrollment><Etiology><Exhibits><Family><Food><Food Intake><Future><Genetic><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Risk><Genetic Susceptibility><Genetic predisposing factor><Genetic propensity><Goals><Healthy Eating><Heterogeneity><Hyperphagia><Informal Social Control><Inherited Predisposition><Inherited Susceptibility><Intake><Intervention Strategies><Life><Longitudinal Studies><Longitudinal Surveys><Measurement><Measures><Mediating><Mediation><Modeling><Modification><Needs Assessment><Negotiating><Negotiation><Neurobiology><Nursery Schools><Obesity><Overeating><Parenting><Parenting behavior><Parents><Predisposition><Prevention program><Quetelet index><Research><Risk Factors><Self Regulation><Shapes><Single Base Polymorphism><Single Nucleotide Polymorphism><Stimulus><Susceptibility><Testing><Time><Work><adiposity><age 2><age 2 years><age 5><age 5 years><aged 2 years><aged two years><ages><attentional bias><causation><child adiposity><child obesity><childhood adiposity><childhood obesity><childrearing><cohort><corpulence><design><designing><developmental><disease causation><early childhood><eating in absence of hunger><enroll><eye tracking><feeding><five year old><five years of age><food avoidance><genetic risk factor><genetic vulnerability><genetically predisposed><inherited factor><kids><life-time risk><lifetime risk><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal research study><longitudinal study design><neurobiological><new approaches><novel><novel approaches><novel strategies><novel strategy><obese children><obesigenic><obesity during childhood><obesity genetics><obesity in children><obesity prevention><obesity risk><obesogenic><parent><pediatric obesity><polygenetic risk scores><polygenic risk score><polyphagia><pre-k><pre-kindergarten><preschool><prevent obesity><prospective><prospective test><response><risk for obesity><risk of obesity><single nucleotide variant><skills><theories><trait><two year old><two years of age><visual tracking><younger age><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

John M Jakicic

UNIVERSITY OF KANSAS MEDICAL CENTER, KANSAS CITY, KS

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$672,748

FY 2026

Project Title

Effectiveness of the Addition of Yoga to a Behavioral Weight Loss Intervention for Adults with Overweight or Obesity

Grant Number:

5R01DK135735-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Overweight and obesity are public health problems and contribute to numerous chronic diseases. Most Behavioral Weight Loss Interventions (BWI) have typically included aerobic forms of exercise (e.g., brisk walking) and have shown that this form of physical activity enhances weight loss compared to d...

Research Terms

<21+ years old><Acute><Adult><Adult Human><Advisory Committees><Aerobic><Affect><BMI><BMI percentile><BMI z-score><Behavioral><Blood Pressure><Body Composition><Body Weight Changes><Body Weight decreased><Body mass index><Chronic><Chronic Disease><Chronic Illness><Clinical Trials Design><Data><Diet><Distress><Eating><Eating Behavior><Effectiveness><Eligibility><Eligibility Determination><Emotional Depression><Energy Expenditure><Energy Metabolism><Ethnic Origin><Ethnicity><Exercise><Focus Groups><Food Intake><Guidelines><Health><Health Benefit><Hunger><Intervention><Measures><Mental Depression><Mental Health><Mental Hygiene><Methodology><Mind-Body Intervention><Mind-Body Medicine><Moods><Muscle><Muscle Tissue><Obesity><Outcome><Overweight><Participant><Patients><Pattern><Physical activity><Pilot Projects><Process Measure><Protocol Screening><Psychological Health><Public Health><Quetelet index><Race><Races><Randomization trial><Randomized><Recommendation><Reducing diet><Reporting><Research><Research Design><Rest><Safety><Satiation><Science><Sedentary behavior><Sedentary life-style><Sleep><Stress><Study Type><Task Forces><Walking><Weight Change><Weight Loss><Weight Reduction><Work><Yoga><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><advisory team><body weight loss><cardiorespiratory fitness><cardiorespiratory health><chronic disorder><corpulence><depression><depression symptom><depressive><depressive symptoms><dietary approach><diets><effective intervention><evidence base><fitness><high standard><improved><light intensity><mind body approach><mind body medicine skills><mind body techniques><mind body therapy><mind body treatments><mind body wellness><mindfulness><moderate-to-vigorous physical activity><muscular><novel><nutritional approach><obese patients><patients with obesity><perceived stress><perception of stress><pilot study><primary outcome><progression risk><psychologic><psychological><racial><racial background><racial origin><randomisation><randomization><randomized trial><randomized, clinical trials><randomly assigned><response><satiety><secondary outcome><sedentary lifestyle><self-reported stress><sex><stress perception><study design><systematic review><trial design><vigorous intensity><weight loss intervention><weight loss therapy><weight loss treatment><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kristina H Lewis

HARVARD PILGRIM HEALTH CARE, INC., Canton, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$670,441

FY 2026

Project Title

Comparative effectiveness of anti-obesity medications for cardiometabolic health outcomes and health services use

Grant Number:

5R01HL171293-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Over 40% of US adults have obesity, many with weight-related complications such as hypertension and diabetes. Current clinical guidelines suggest lifestyle change as the first-line obesity treatment approach, but this does not produce sustained clinically-significant weight ...

Research Terms

<2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate><21+ years old><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Age><Agonist><American><Amfebutamone><Anti-Obesity Agents><Anti-Obesity Drugs><Apoplexy><Arrhythmia><BMI><BMI percentile><BMI z-score><Bariatrics><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body Weight><Body Weight decreased><Body mass index><Brain Vascular Accident><Bupropion><Cardiac Arrhythmia><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Chronic Disease><Chronic Illness><Clinical><Clinical Research><Clinical Services><Clinical Study><Clinical Trials><Comparative Effectiveness Research><Complication><Conditioning Therapy><Data><Data Set><Development><Diabetes Mellitus><Drug Prescribing><Drug Prescriptions><Drug Therapy><Drugs><Dyslipidemias><ED visit><ER visit><Economics><Effectiveness><Eligibility><Eligibility Determination><Emergencies><Emergency Situation><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Epidemiology><Event><FDA approved><GLP-1><Glp-1><Guidelines><Head><Health><Health Care><Health Care Costs><Health Care Utilization><Health Costs><Health Insurance><Health Services><Heart Arrhythmias><Heart Vascular><Heart failure><Hospital Admission><Hospitalization><Hypertension><Incidence><Individual><Intention><Intervention><Ketosis-Resistant Diabetes Mellitus><Lead><Length of Stay><Life Style><Lifestyle><Maturity-Onset Diabetes Mellitus><Measures><Medical Care Costs><Medication><Medicine><Morbid Obesity><Myocardial Infarct><Myocardial Infarction><NIDDM><Nalorex><Naltrexone><Nemexin><New Agents><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Number of Days in Hospital><Obesity><Obesity Epidemic><Out-patients><Outcome><Outpatients><Patients><Pb element><Pharmaceutical Preparations><Pharmacies><Pharmacological Treatment><Pharmacotherapy><Pharmacy facility><Phentermine><Physicians><Policies><Procedures><Protocol Screening><Provider><Qualifying><Quetelet index><ReVia><Recommendation><Research><Risk><Safety><Severe obesity><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><T2 DM><T2D><T2DM><Techniques><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Update><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Visit><Vivitrol><Weight><Weight Loss><Weight Reduction><Wellbutrin><active followup><adiposity><adult onset diabetes><adulthood><ages><alpha,alpha-dimethyl-benzeneethanamine><anti-obesity compounds><anti-obesity medications><anti-obesity therapeutics><bariatric surgery><behavior intervention><behavioral intervention><body weight loss><brain attack><buproprion><cardiac failure><cardiac infarct><cardiometabolic><cardiometabolism><cerebral vascular accident><cerebrovascular accident><chronic disorder><circulatory system><clinical practice><clinical significance><clinically significant><co-morbid><co-morbidity><cohort><comorbidity><comparative><comparative effectiveness><comparative effectiveness study><coronary attack><coronary infarct><coronary infarction><corpulence><cost><customized therapy><customized treatment><design><designing><developmental><diabetes><drug intervention><drug treatment><drug/agent><economic><epidemiologic><epidemiological><extreme obesity><follow up><follow-up><followed up><followup><gastric banding><gastric bypass surgery><glucagon-like peptide 1><health care service use><health care service utilization><health insurance plan><health service use><health service utilization><heart attack><heart infarct><heart infarction><heavy metal Pb><heavy metal lead><high blood pressure><hospital days><hospital length of stay><hospital stay><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><implantable gastric stimulation banding><improved><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><insurance claims><ketosis resistant diabetes><life style intervention><lifestyle intervention><liraglutide><maturity onset diabetes><medical costs><medical expenses><medication prescription><obese patients><obesity intervention><obesity surgery><obesity therapy><obesity treatment><patient specific therapies><patient specific treatment><patients with obesity><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><pharmacy benefit><prescribed medication><programs><revascularization><sex><stomach stapling><stroked><strokes><tailored medical treatment><tailored therapy><tailored treatment><topiramate><treatment choice><type 2 DM><type II DM><type two diabetes><unique treatment><weight loss surgery><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Darren Toh

HARVARD PILGRIM HEALTH CARE, INC., Canton, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$670,441

FY 2026

Project Title

Comparative effectiveness of anti-obesity medications for cardiometabolic health outcomes and health services use

Grant Number:

5R01HL171293-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Over 40% of US adults have obesity, many with weight-related complications such as hypertension and diabetes. Current clinical guidelines suggest lifestyle change as the first-line obesity treatment approach, but this does not produce sustained clinically-significant weight ...

Research Terms

<2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate><21+ years old><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Age><Agonist><American><Amfebutamone><Anti-Obesity Agents><Anti-Obesity Drugs><Apoplexy><Arrhythmia><BMI><BMI percentile><BMI z-score><Bariatrics><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body Weight><Body Weight decreased><Body mass index><Brain Vascular Accident><Bupropion><Cardiac Arrhythmia><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Chronic Disease><Chronic Illness><Clinical><Clinical Research><Clinical Services><Clinical Study><Clinical Trials><Comparative Effectiveness Research><Complication><Conditioning Therapy><Data><Data Set><Development><Diabetes Mellitus><Drug Prescribing><Drug Prescriptions><Drug Therapy><Drugs><Dyslipidemias><ED visit><ER visit><Economics><Effectiveness><Eligibility><Eligibility Determination><Emergencies><Emergency Situation><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Epidemiology><Event><FDA approved><GLP-1><Glp-1><Guidelines><Head><Health><Health Care><Health Care Costs><Health Care Utilization><Health Costs><Health Insurance><Health Services><Heart Arrhythmias><Heart Vascular><Heart failure><Hospital Admission><Hospitalization><Hypertension><Incidence><Individual><Intention><Intervention><Ketosis-Resistant Diabetes Mellitus><Lead><Length of Stay><Life Style><Lifestyle><Maturity-Onset Diabetes Mellitus><Measures><Medical Care Costs><Medication><Medicine><Morbid Obesity><Myocardial Infarct><Myocardial Infarction><NIDDM><Nalorex><Naltrexone><Nemexin><New Agents><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Number of Days in Hospital><Obesity><Obesity Epidemic><Out-patients><Outcome><Outpatients><Patients><Pb element><Pharmaceutical Preparations><Pharmacies><Pharmacological Treatment><Pharmacotherapy><Pharmacy facility><Phentermine><Physicians><Policies><Procedures><Protocol Screening><Provider><Qualifying><Quetelet index><ReVia><Recommendation><Research><Risk><Safety><Severe obesity><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><T2 DM><T2D><T2DM><Techniques><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Update><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Visit><Vivitrol><Weight><Weight Loss><Weight Reduction><Wellbutrin><active followup><adiposity><adult onset diabetes><adulthood><ages><alpha,alpha-dimethyl-benzeneethanamine><anti-obesity compounds><anti-obesity medications><anti-obesity therapeutics><bariatric surgery><behavior intervention><behavioral intervention><body weight loss><brain attack><buproprion><cardiac failure><cardiac infarct><cardiometabolic><cardiometabolism><cerebral vascular accident><cerebrovascular accident><chronic disorder><circulatory system><clinical practice><clinical significance><clinically significant><co-morbid><co-morbidity><cohort><comorbidity><comparative><comparative effectiveness><comparative effectiveness study><coronary attack><coronary infarct><coronary infarction><corpulence><cost><customized therapy><customized treatment><design><designing><developmental><diabetes><drug intervention><drug treatment><drug/agent><economic><epidemiologic><epidemiological><extreme obesity><follow up><follow-up><followed up><followup><gastric banding><gastric bypass surgery><glucagon-like peptide 1><health care service use><health care service utilization><health insurance plan><health service use><health service utilization><heart attack><heart infarct><heart infarction><heavy metal Pb><heavy metal lead><high blood pressure><hospital days><hospital length of stay><hospital stay><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><implantable gastric stimulation banding><improved><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><insurance claims><ketosis resistant diabetes><life style intervention><lifestyle intervention><liraglutide><maturity onset diabetes><medical costs><medical expenses><medication prescription><obese patients><obesity intervention><obesity surgery><obesity therapy><obesity treatment><patient specific therapies><patient specific treatment><patients with obesity><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><pharmacy benefit><prescribed medication><programs><revascularization><sex><stomach stapling><stroked><strokes><tailored medical treatment><tailored therapy><tailored treatment><topiramate><treatment choice><type 2 DM><type II DM><type two diabetes><unique treatment><weight loss surgery><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Elissa S. Epel

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$663,833

FY 2026

Project Title

Multi-Level Trial of a Workplace Sales Ban of Sugary Beverages and Brief Motivational Counseling Intervention on Adiposity

Grant Number:

5R01DK132870-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Sugar-sweetened beverages (SSBs, e.g., sodas, sports drinks, “fruit” drinks, bottled teas, coffees) have emerged as a key dietary risk factor for obesity and type 2 diabetes. We propose a double-randomized controlled trial of a multilevel workplace intervention that combines an employer-sp...

Research Terms

<21+ years old><Abdominal obesity><Adopted><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Alcohol Chemical Class><Alcohols><American><American diet><Android fat distribution><Attention><BMI><BMI percentile><BMI z-score><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Beverages><Blood><Blood Reticuloendothelial System><Blood Sample><Blood Serum><Blood specimen><Body mass index><California><Calories><Central obesity><Centripetal obesity><Clinical Trials><Coffee><Conditioning Therapy><Consumption><Counseling><Cues><Data><Diabetes Mellitus><Diet Composition><Dietary Assessment><Employee><Enrollment><Exposure to><Food Preferences><Fruit><Health><Health Care Costs><Health Care Systems><Health Costs><Health Food><Health system><Home><Hospitals><Hour><Incentives><Individual><Intake><Intervention><Investments><Job Location><Job Place><Job Setting><Job Site><Ketosis-Resistant Diabetes Mellitus><Knowledge><Lipids><Liquid substance><Low income><Magic><Maturity-Onset Diabetes Mellitus><Mediating><Mediation><Metabolic><Metabolic Diseases><Metabolic Disorder><Modeling><Motivation><NIDDM><Negotiating><Negotiation><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutritious food><Obesity><Occupational Status><Outcome><Participant><Pilot Projects><Policies><Prevention><Public Health><Quetelet index><Randomization trial><Randomized><Randomized, Controlled Trials><Research><Risk><Risk Factors><Role><Sales><Schools><Science><Self Administered><Self Administration><Serum><Site><Slow-Onset Diabetes Mellitus><Source><Sports><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Tea><Testing><Thesaurismosis><Tobacco><Truncal obesity><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Work><Work Location><Work Place><Work-Site><Workplace><Worksite><adiposity><adult onset diabetes><adulthood><assess effectiveness><behavior change><behavior intervention><behavioral intervention><brief intervention><brief therapy><brief treatment><calorie><corpulence><cost><craving><delivered remotely><determine effectiveness><diabetes><diet choice><diet preference><dietary><dietary choice><dietary composition><dietary fruit><dietary preferences><drinking><effectiveness assessment><effectiveness evaluation><enroll><ethnic minority><evaluate effectiveness><examine effectiveness><experience><fluid><food choice><food environment><healthy food><high risk><high risk group><high risk individual><high risk people><high risk population><homes><improved><insulin sensitivity><intervention design><ketosis resistant diabetes><liquid><maturity onset diabetes><metabolism disorder><obesity prevention><pilot study><prevent obesity><primary outcome><programs><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><remote assessment><remote delivery><remote evaluation><secondary outcome><social role><soda><soft drink><sugar><sweetened beverage><synergism><therapy design><treatment design><type 2 DM><type II DM><type two diabetes><visceral obesity><waist circumference><work setting>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Laura A Schmidt

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$663,833

FY 2026

Project Title

Multi-Level Trial of a Workplace Sales Ban of Sugary Beverages and Brief Motivational Counseling Intervention on Adiposity

Grant Number:

5R01DK132870-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Sugar-sweetened beverages (SSBs, e.g., sodas, sports drinks, “fruit” drinks, bottled teas, coffees) have emerged as a key dietary risk factor for obesity and type 2 diabetes. We propose a double-randomized controlled trial of a multilevel workplace intervention that combines an employer-sp...

Research Terms

<21+ years old><Abdominal obesity><Adopted><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Alcohol Chemical Class><Alcohols><American><American diet><Android fat distribution><Attention><BMI><BMI percentile><BMI z-score><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Beverages><Blood><Blood Reticuloendothelial System><Blood Sample><Blood Serum><Blood specimen><Body mass index><California><Calories><Central obesity><Centripetal obesity><Clinical Trials><Coffee><Conditioning Therapy><Consumption><Counseling><Cues><Data><Diabetes Mellitus><Diet Composition><Dietary Assessment><Employee><Enrollment><Exposure to><Food Preferences><Fruit><Health><Health Care Costs><Health Care Systems><Health Costs><Health Food><Health system><Home><Hospitals><Hour><Incentives><Individual><Intake><Intervention><Investments><Job Location><Job Place><Job Setting><Job Site><Ketosis-Resistant Diabetes Mellitus><Knowledge><Lipids><Liquid substance><Low income><Magic><Maturity-Onset Diabetes Mellitus><Mediating><Mediation><Metabolic><Metabolic Diseases><Metabolic Disorder><Modeling><Motivation><NIDDM><Negotiating><Negotiation><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutritious food><Obesity><Occupational Status><Outcome><Participant><Pilot Projects><Policies><Prevention><Public Health><Quetelet index><Randomization trial><Randomized><Randomized, Controlled Trials><Research><Risk><Risk Factors><Role><Sales><Schools><Science><Self Administered><Self Administration><Serum><Site><Slow-Onset Diabetes Mellitus><Source><Sports><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Tea><Testing><Thesaurismosis><Tobacco><Truncal obesity><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Work><Work Location><Work Place><Work-Site><Workplace><Worksite><adiposity><adult onset diabetes><adulthood><assess effectiveness><behavior change><behavior intervention><behavioral intervention><brief intervention><brief therapy><brief treatment><calorie><corpulence><cost><craving><delivered remotely><determine effectiveness><diabetes><diet choice><diet preference><dietary><dietary choice><dietary composition><dietary fruit><dietary preferences><drinking><effectiveness assessment><effectiveness evaluation><enroll><ethnic minority><evaluate effectiveness><examine effectiveness><experience><fluid><food choice><food environment><healthy food><high risk><high risk group><high risk individual><high risk people><high risk population><homes><improved><insulin sensitivity><intervention design><ketosis resistant diabetes><liquid><maturity onset diabetes><metabolism disorder><obesity prevention><pilot study><prevent obesity><primary outcome><programs><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><remote assessment><remote delivery><remote evaluation><secondary outcome><social role><soda><soft drink><sugar><sweetened beverage><synergism><therapy design><treatment design><type 2 DM><type II DM><type two diabetes><visceral obesity><waist circumference><work setting>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Allison Sylvetsky

GEORGE WASHINGTON UNIVERSITY, WASHINGTON, DC

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$662,577

FY 2026

Project Title

Effects of a non-nutritive sweetener reduction intervention in pregnancy and lactation on maternal and infant outcomes (the SWEETPEA trial)

Grant Number:

5R01HD107427-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Increasing evidence demonstrates that suboptimal conditions in the womb, including poor maternal nutrition, contributes to obesity and cardiometabolic disease risk. One potential contributor to poor maternal nutrition is chronic consumption of non-nutritive sweeteners (NNS). Studies indicat...

Research Terms

<21+ years old><Adherence><Adult><Adult Human><Affect><Age Months><Air><Automobile Driving><BMI><BMI percentile><BMI z-score><Beverages><Blood Glucose><Blood Sugar><Body Composition><Body fat><Body mass index><Breast Milk><Breastmilk><Cardiometabolic Disease><Cardiometabolic Disorder><Childhood><Chronic><Cohort Studies><Consultations><Consumption><Control Groups><Counseling><Data><Development><Dietitian><Disease><Disorder><Ethics><Exclusive Breastfeeding><Exposure to><Fats><Fatty acid glycerol esters><Feces><Food><Functional Metagenomics><Future><GI microbiome><GI microbiota><Gastrointestinal microbiota><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose Intolerance><Growth><Guidelines><Health><Home><Hour><Human><Human Characteristics><Human Milk><Human Mother's Milk><Human Nature><Hypoglycemia><Infant><Infant Health><Inflammation><Inflammatory><Intake><Intervention><Lactation><Leanness><Life><Mammary Gland Milk><Maternal Health><Maternal Nutrition><Maternal diet><Measures><Metabolic><Metagenomics><Mice><Mice Mammals><Microbe><Modern Man><Mother's Milk><Mothers><Murine><Mus><OGTT><Obesity><Observational Study><Oral Glucose Tolerance Test><Outcome><Pathway interactions><Physiologic><Physiological><Plethysmography><Postpartum Period><Pregnancy><Pregnancy-Induced Diabetes><Pregnant Women><Prospective, cohort study><Quetelet index><Randomized><Randomized, Controlled Trials><Recommendation><Reporting><Research><Risk Factors><Rodent><Rodent Model><Rodentia><Rodents Mammals><Safety><Shapes><Solid><Sweeteners><Sweetening Agents><Thinness><Tissue Growth><Toxicology><Transmission><United States><Urine><Uterus><Weight><Woman><adiposity><adulthood><blood glucose regulation><cardiometabolic risk><cohort research study><cohort survey><consultation><corpulence><developmental><diabetes risk><dietary><digestive tract microbiome><disease risk><disorder risk><dosage><driving><early life exposure><enteric microbial community><enteric microbiome><enteric microbiota><ethical><expectant mother><expectant women><expecting mother><expecting women><exposed in utero><fetal><fetal exposure><gastrointestinal microbial flora><gastrointestinal microbiome><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><gut community><gut dysbiosis><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiome><gut microbiome of infant><gut microbiota><gut microbiotic><gut microflora><gut-associated microbiome><homes><hypoglycemic><hypoglycemic episodes><improved><in utero><in utero exposure><individuals who are pregnant><infant adiposity><infant gut microbiome><infant obesity><infant outcome><infantile obesity><insulin sensitivity><intergenerational><intestinal biome><intestinal flora><intestinal microbiome><intestinal microbiota><intestinal microflora><intestinal tract microflora><intra-uterine environmental exposure><intrauterine environmental exposure><lactating><lactational><maternal milk><maternal nutrition during pregnancy><maternal outcome><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mother nutrition><mother outcome><neonate gut microbiome><newborn gut microbiome><obesity among infants><obesity in infants><observational research study><observational survey><offspring><offspring obesity><ontogeny><pathway><pediatric><people who are pregnant><post-partum><postnatal><pregnancy diabetes><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prenatal exposure><prenatally exposed><randomisation><randomization><randomized control trial><randomly assigned><recruit><stool><those who are pregnant><transmission process><unborn><weights><womb><women who are pregnant>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Eric Arterburn

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$649,786

FY 2026

Project Title

Comparative Effectiveness and Safety of Metabolic/Bariatric Surgery, GLP-1, and SGLT-2 Medications for Patients with Obesity and Type 2 Diabetes

Grant Number:

5R01DK135515-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/6/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY More than 12 million Americans currently live with both obesity and type 2 diabetes (T2D), putting them in one of the highest risk groups for developing serious microvascular and macrovascular complications. The Ameri- can Diabetes Association’s clinical practice guidelines recommend...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rozalina Grubina McCoy

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$649,786

FY 2026

Project Title

Comparative Effectiveness and Safety of Metabolic/Bariatric Surgery, GLP-1, and SGLT-2 Medications for Patients with Obesity and Type 2 Diabetes

Grant Number:

5R01DK135515-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/6/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY More than 12 million Americans currently live with both obesity and type 2 diabetes (T2D), putting them in one of the highest risk groups for developing serious microvascular and macrovascular complications. The Ameri- can Diabetes Association’s clinical practice guidelines recommend...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

BRENDA M DAVY

VIRGINIA POLYTECHNIC INST AND ST UNIV, BLACKSBURG, VA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$648,013

FY 2026

Project Title

Water Intake and Weight Control in Older Adults

Grant Number:

5R01DK135410-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract The lack of practical and effective strategies to manage hunger and adhere to a weight management intervention represents a critical barrier to the weight management field. In proof-of-concept efficacy studies, we have demonstrated that premeal water consumption (500 ml) acu...

Research Terms

<21+ years old><Acute><Address><Adherence><Adult><Adult Human><American><Appetite><Appetite Regulation><Area><Attention><Behavior><Behavioral Mechanisms><Blood Serum><Body Weight decreased><Caloric Intake><Clinical><Clinical Practice Guideline><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Consumption><Control Groups><Decline in mobility><Decrease in mobility><Decreased mobility><Dehydration><Desire for food><Diet><Diminished mobility><Disease><Disorder><Disturbance in cognition><Endocrine Gland Secretion><Energy Intake><Esthesia><Evaluation><Evidence based practice guidelines><Face><Goals><Health Benefit><High Prevalence><Hormones><Humulin R><Hunger><Hydration><Hydration status><Hydrogen Oxide><Impaired cognition><Instruction><Insulin><Intervention><Intervention Trial><Interventional trial><Kidney Calculi><Kidney Stones><Link><Maintenance><Measures><Mechanisms of Behavior and Behavior Change><Mediating><Mediator><Medical Care Costs><Mobility decline><Mobility impairment><NIH><National Institutes of Health><Novolin R><Nutrition Research><Nutritional Study><Obesity><Osmolalities><Outcome><Overweight><Participant><Performance><Phase><Population><Randomized, Controlled Trials><Recommendation><Reduced mobility><Reduction in mobility><Regular Insulin><Renal Calculi><Renal Stone><Research><Satiation><Sensation><Serum><Stomach><Strategic Planning><Therapeutic Hormone><Time><United States National Institutes of Health><Urinary tract infection><Urinary tract infectious disease><Urine><Water><Water Intake><Water consumption><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Weight maintenance regimen><Woman><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><aged><attentional control><behavior mechanism><body water dehydration><body weight gain><body weight increase><body weight loss><caloric dietary content><care as usual><clinical practice and guidelines><cognitive dysfunction><cognitive function><cognitive loss><compare to control><comparison control><corpulence><cost><diet adherence><dietary><dietary adherence><dietary guidelines><diets><disability risk><drinking water><efficacy study><evidence base><evidence based guidelines><evidence based recommendations><executive control><executive function><faces><facial><fasting glucose><gastric><healthy lifestyle><improved><life style intervention><lifestyle intervention><medical costs><medical expenses><men><mid life><mid-life><middle age><middle aged><midlife><nutritional guideline><obesity intervention><obesity risk><obesity therapy><obesity treatment><older adult><older adulthood><overweight adults><prevent><preventing><randomized control trial><randomized controlled design><risk for obesity><risk of obesity><satiety><success><treatment as usual><trial design><urinary infection><usual care><usual care arm><usual care control group><weight control><weight maintenance><weight management><weights><work group><working group><wt gain><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Elizabeth Anne Thomas

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$645,432

FY 2026

Project Title

Effects of early vs. late time restricted eating vs. daily caloric restriction on weight loss and metabolic outcomes in adults with obesity

Grant Number:

5R01DK132372-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/5/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The goal of this proposal is to determine the optimal time restricted eating (TRE) window to produce weight loss in adults with overweight or obesity. Daily caloric restriction (DCR), the current standard of care dietary strategy for weight loss, produces 5-7% weight loss in the context of a guideli...

Research Terms

<21+ years old><Active Follow-up><Adherence><Adult><Adult Human><Appetite><Attention><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Blood Pressure><Body Composition><Body Weight><Body Weight Changes><Body Weight decreased><Caloric Intake><Caloric Restriction><Clinical Data><Conditioning Therapy><D-Glucose><Desire for food><Dextrose><Diet><Dietary Intervention><Dietary quality><Eating><Effectiveness><Energy Intake><Failure><Fats><Fatty acid glycerol esters><Food Intake><Glucose><Goals><Guidelines><Health><Hour><Individual><Intervention Trial><Interventional trial><Literature><Metabolic><Nutrition Interventions><Nutritional><Nutritional Interventions><Obesity><Outcome><Overweight><Participant><Persons><Physical activity><Pilot Projects><Public Health><Randomized><Recommendation><Sample Size><Sleep><Time><Time-restricted eating><Time-restricted feeding><Weight><Weight Change><Weight Loss><Weight Reduction><active followup><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><assess effectiveness><behavior intervention><behavioral intervention><blood lipid><body weight loss><caloric dietary content><calorie restriction><cardiometabolic><cardiometabolism><clinical significance><clinically significant><corpulence><design><designing><determine effectiveness><diet adherence><diet intervention><diet quality><dietary><dietary adherence><dietary restriction><diets><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><evidence base><examine effectiveness><follow up><follow-up><followed up><followup><food restriction><improved><improvement on sleep><insight><insulin sensitivity><novel><nutritious><obesity intervention><obesity therapy><obesity treatment><pilot study><pre-clinical><preclinical><primary outcome><randomisation><randomization><randomly assigned><restricted diet><sedentary><sleep amount><sleep duration><sleep episode><sleep improvement><sleep interval><sleep length><sleep period><sleep quantity><sleep time><standard of care><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><treatment guidelines><trial design><weight loss program><weight loss programming><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sean Hartig

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$642,578

FY 2026

Project Title

Molecular regulation of leptin bioavailability

Grant Number:

5R01DK138018-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/20/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT The obesity epidemic contributes to the increased health burden of chronic inflammatory conditions, including insulin resistance, type 2 diabetes mellitus (T2DM), fatty liver, and cardiovascular disease. New strategies for prevention and treatment are crucial to improve the quality of life ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Robert G Weaver

UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, COLUMBIA, SC

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$642,017

FY 2026

Project Title

Increasing Low-income Children's Access to Healthy Structured Programming to Reduce Obesity

Grant Number:

5R01DK133169-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Disparities in overweight and obesity (OWOB) prevalence between children (ages 5-11) from low- and middle-to- high-income families persist. The structured days hypothesis posits that structure within a day, defined as a pre- planned, segmented, and adult-supervised compulsory environment (like a sch...

Research Terms

<0-11 years old><21+ years old><4th grade><5 year old><5 years of age><Address><Administrator><Adult><Adult Human><BMI><BMI percentile><BMI z-score><Behavior><Body fat><Body mass index><Calendar><Child><Child Youth><Children (0-21)><Communities><Decrease disparity><Diet><Disparities><Disparity><Economic Income><Economical Income><Effectiveness><Environment><Family><Fats><Fatty acid glycerol esters><Fee-for-Service Plans><Fees for Service><Food><Food Stamps><Health><Healthy diet><History><Hour><Household><Incentives><Income><Intervention><Intervention Strategies><Interview><Learning><Literature><Low income><Lower disparity><Obesity><Outcome><Overweight><Parents><Participant><Physical activity><Play><Policies><Prevalence><Public Health><Quetelet index><Randomized><Recording of previous events><Reporting><Role><Schools><Services><Side><Sleep><Sleep disturbances><Structure><Supplemental Nutrition Assistance Program><Testing><Time><US Department of Agriculture><USDA><United States><United States Department of Agriculture><Weight><Weight Gain><Weight Increase><aberrant sleep><adiposity><adulthood><after-school program><afterschool program><age 5><age 5 years><assessing cost effectiveness><balanced diet><barriers to implementation><body weight gain><body weight increase><child adiposity><child obesity><childhood adiposity><childhood obesity><corpulence><cost><cost-effectiveness evaluation><design><designing><determine cost effectiveness><diets><disparities in income><disparity reduction><disrupted sleep><disturbed sleep><evaluate cost-effectiveness><examine cost effectiveness><excessive weight gain><experience><extreme weight gain><five year old><five years of age><food insecure><food insecurity><food scarcity><fourth grade><good diet><histories><impaired sleep><implementation barriers><implementation challenges><income disparities><incomes><innovate><innovation><innovative><irregular sleep><kids><learning community><low food security><lower income families><mitigate disparity><novel><obese children><obesigenic><obesity during childhood><obesity in children><obesity intervention><obesity therapy><obesity treatment><obesogenic><parent><pediatric obesity><prevent><preventing><primary outcome><program costs><programs><randomisation><randomization><randomly assigned><reduce disparity><reduction in disparity><secondary outcome><serious weight gain><severe weight gain><sleep disruption><sleep dysregulation><sleep pattern><sleep routine><sleep schedule><sleep/wake disruption><sleep/wake disturbance><sleep/wake patterns><social role><summer program><summer session><systematic review><treatment program><voucher><weights><wt gain><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LICY LORENA YANES CARDOZO

UNIVERSITY OF MISSISSIPPI MED CTR, JACKSON, MS

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$638,534

FY 2026

Project Title

Role of obesity in blood pressure regulation and insulin resistance in Polycystic Ovary Syndrome

Grant Number:

5R01HL171494-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in reproductive-age women. PCOS is diagnosed by elevated androgens, ovulatory dysfunction, and polycystic ovaries. Women with PCOS have a high prevalence of cardiovascular risk factors (CRFs), such as obesity, insulin resistance ...

Research Terms

<3-D><3-Dimensional><3D><3D cell culture><3D culture><5 alpha-Dihydrotestosterone><5-alpha-DHT><ACE2><ACRP30 protein><Address><Adipocytes><Adipose Cell><Adipose tissue><Adverse effects><Affect><Agonist><Androgenic Agents><Androgenic Compounds><Androgens><Androstanolone><AngII><Angiotensin AT1 Receptor><Angiotensin Converting Enzyme><Angiotensin I-Converting Enzyme><Angiotensin II><Angiotensin II Type 1 Receptor><Angiotensins><Animal Model><Animal Models and Related Studies><Applications Grants><Autocrine Systems><BP control><BP homeostasis><BP management><BP reduction><BP regulation><Blood Plasma><Blood Pressure><Body Weight decreased><CD143 Antigens><Carboxycathepsin><Cardiovascular Diseases><Cell Communication and Signaling><Cell Culture Techniques><Cell Signaling><Common Rat Strains><Control Groups><Data><Diagnosis><Dihydrotestosterone><Dipeptidyl Peptidase A><Dysfunction><Enacard><Enalapril><Endocrine Diseases><Endocrine Diseases and Manifestations><Endocrine Gland Secretion><Endocrine System Diseases><Enzyme Inhibition><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Female><Functional disorder><Goals><Grant Proposals><Health><High Prevalence><Hormones><Human><Humulin R><Hyperandrogenemia><Image><Impairment><In Vitro><Insulin><Insulin Resistance><Intracellular Communication and Signaling><KO mice><Kininase A><Kininase II><Knock-out Mice><Knockout Mice><Knowledge><Laboratories><Lead><Leanness><Lipocytes><Mature Lipocyte><Mature fat cell><Measurement><Measures><Mediating><Metabolic><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Molecular Target><Murine><Mus><Novolin R><Null Mouse><Obesity><Pathway interactions><Pb element><Peptides><Peptidyl-Dipeptidase A><Physiologic><Physiological><Physiopathology><Plasma><Plasma Serum><Play><Polycystic Ovarian Disease><Polycystic Ovarian Syndrome><Polycystic Ovary Syndrome><Rat><Rats Mammals><Rattus><Receptor Protein><Receptor, Angiotensin, Type 1><Regular Insulin><Renin-Angiotensin System><Renitec><Renitek><Research><Research Proposals><Reticuloendothelial System, Serum, Plasma><Role><Sclerocystic Ovarian Degeneration><Sclerocystic Ovary Syndrome><Signal Transduction><Signal Transduction Systems><Signaling><Stanolone><System><Testing><Testosterone><Therapeutic Agents><Therapeutic Androgen><Therapeutic Androstanolone><Therapeutic Hormone><Therapeutic Testosterone><Thinness><Trans-Testosterone><Translating><Vasotec><Visceral><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Woman><adipocyte complement-related protein 30-kDa><adipocyte, C1q and collagen domain containing protein><adipocytokines><adipokines><adiponectin><adipose><adiposity><androgen excess><angiotensin II type I receptor><angiotensin converting enzyme 2><angiotensin converting enzyme II><apM-1 protein><apM1 (adipose-specific) protein><arm><autocrine><biological signal transduction><blood pressure control><blood pressure elevation><blood pressure homeostasis><blood pressure management><blood pressure reduction><blood pressure regulation><body weight gain><body weight increase><body weight loss><cardiometabolic><cardiometabolism><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><cell culture><cell cultures><childbearing age><clinical relevance><clinically relevant><compare to control><comparison control><corpulence><elevated blood pressure><endocrine disorder><feeding><fertile age><heavy metal Pb><heavy metal lead><imaging><implantation><improved><in vivo><increase in blood pressure><increased blood pressure><innovate><innovation><innovative><insulin resistant><insulin tolerance><lower BP><lower blood pressure><lowers blood pressure><male><model of animal><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><ovarian dysfunction><ovulatory dysfunction><paracrine><pathophysiology><pathway><pharmacologic><polycystic ovary><polycystic ovary disease><polycystic ovary disorder><prevent><preventing><receptor><reduce BP><reduce blood pressure><reduction in BP><reduction in blood pressure><regulate BP><regulate blood pressure><reproductive age><reproductive years><response><social role><subcutaneous><subdermal><therapeutically effective><three dimensional><three dimensional cell culture><white adipose tissue><wt gain><wt-loss><yellow adipose tissue><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jerica M Berge

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$634,951

FY 2026

Project Title

Examining How Psychosocial Stress Gets "Under the Skin" and Leads to Cardiovascular Disease Risk in Diverse Children: A Mixed-Methods Study

Grant Number:

5R01HL156994-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Recent reports from the American Journal of Public Health and the American Psychological Association identified a critical need to examine mechanisms by which exposure to psychosocial stress in childhood increases the risk for obesity and cardiovascular disease (CVD) in adulthood. Given the...

Research Terms

<0-11 years old><12-20 years old><13 year old><13 years of age><21+ years old><5 year old><5 years of age><6-11 years old><9 year old><9 years of age><Accelerometer><Active Follow-up><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Aeroseb-HC><Affect><African American><Afro American><Afroamerican><American><American Psychological Association><BMI><BMI percentile><BMI z-score><Behavioral><Biologic Factor><Biological><Biological Factors><Biological Markers><Blood Pressure><Body Composition><Body mass index><COVID-19><CV-19><Cardiac Chronotropism><Cardiovascular Diseases><Cetacort><Child><Child Behavior><Child Health><Child Rearing><Child Youth><Childhood><Children (0-21)><Cohort Studies><Coronavirus Infectious Disease 2019><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Data><Data Collection><Dermacort><Development><Dietary quality><Dimensions><Disadvantaged><Disease><Disorder><Disparities><Disparity><Ecological momentary assessment><Eldecort><Epidemiology><Ethnic Group><Ethnic Origin><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity><Ethnicity People><Ethnicity Population><Exposure to><Family><Family Life Cycle><Field Reports><Focus Groups><Frequencies><HPA axis><Hair><Heart Rate><Hispanic><Household><Hydrocortisone><Hydrocortone><Hytone><Immigrant><Individual><Individuals from minority><Individuals of minority><Interruption><Intervention><Investigators><Journals><Lead><Life Cycle><Life Cycle Stages><Magazine><Measures><Methods><Minority Groups><Minority People><Minority Population><Minority individual><NIH><National Institutes of Health><Native American><Neighborhoods><Nutracort><Obesity><Parenting><Parenting behavior><Parents><Pathway interactions><Pb element><Phase><Politics><Process><Proctocort><Psychosocial Stress><Puberty><Public Health><Quetelet index><Race><Races><Racial Group><Refugees><Reporting><Research Personnel><Researchers><Role><Severities><Skin><Stress><Structural Racism><Survey Instrument><Surveys><Time><United States National Institutes of Health><Weight><accelerometry><active followup><activity monitor><activity tracker><adiposity><adolescence (12-20)><adulthood><age 13><age 13 years><age 5><age 5 years><age 9><age 9 years><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><bio-markers><biologic><biologic marker><biomarker><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><child adiposity><child obesity><childhood adiposity><childhood obesity><childrearing><cohort research study><cohort survey><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><corpulence><design><designing><developmental><diet quality><dietary><disparities in race><disparity due to race><early experience><epidemiologic><epidemiological><ethnic subgroup><ethnicity group><experience><feeding><five year old><five years of age><follow up><follow-up><followed up><followup><heavy metal Pb><heavy metal lead><high risk><human centered design><hypothalamic-pituitary-adrenal (HPA) axis><hypothalamic-pituitary-adrenal axis><hypothalmus-pituitary-adrenal axis><improved><indexing><inequality due to race><inequity due to race><innovate><innovation><innovative><juvenile><juvenile human><kids><life course><middle childhood><nine year old><nine years of age><novel><obese children><obesity during childhood><obesity in children><obesity risk><parent><pathway><pediatric><pediatric obesity><prospective><psychosocial stresses><psychosocial stressors><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial><racial background><racial disparities in health><racial disparity><racial health disparity><racial inequality><racial inequity><racial origin><racial population><racial subgroup><racially unequal><resilience><resilient><retention rate><retention strategy><risk for obesity><risk mitigation><risk of obesity><social role><thirteen year old><thirteen years of age><waist circumference><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JENNIFER ORLET FISHER

TEMPLE UNIV OF THE COMMONWEALTH, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$634,462

FY 2026

Project Title

Deconstructing food parenting approaches to obesity prevention for the highly food motivated child

Grant Number:

5R01DK132642-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

High levels of food motivation among young children are heritable, track over time, and associated with elevated risks of unhealthy eating and obesity. Despite significant growth of family-based obesity prevention efforts, the evidence base is remarkably scant on parenting highly food motivated chil...

Research Terms

<0-11 years old><Address><Authoritarianism><BMI><BMI percentile><BMI z-score><Basic Behavioral Science><Basic Research><Basic Science><Behavioral Research><Body mass index><Care Givers><Caregivers><Child><Child Rearing><Child Youth><Children (0-21)><Consumption><Diet Habits><Dietary Habits><Dietary intake><Dietary quality><Dimensions><Eating><Eating Behavior><Ecological momentary assessment><Equilibrium><Family><Food><Food Intake><Foundations><Generalized Growth><Goals><Growth><Healthy Eating><Heritability><Hyperphagia><Individual Differences><Intake><Intervention><Investigation><Knowledge><Light><Literature><Measures><Methods><Motivation><Nursery Schools><Obesity><Outcome><Overeating><Parenting><Parenting behavior><Parents><Photoradiation><Population Group><Prevention><Prevention Research><Proliferating><Prospective cohort><Quetelet index><Recommendation><Research><Risk><Role><STEM research><Specificity><Structure><Time><Tissue Growth><Unhealthy Diet><Weight><Work><adiposity><authoritarian><balance><balance function><childrearing><corpulence><design><designing><diet quality><dietary><dietary excess><eating habit><eating in absence of hunger><elementary school><evidence base><experience><feeding><goal oriented behavior><grade school><kids><motivated behavior><obesity prevention><obesity risk><ontogeny><parent><parent influence><parental influence><polyphagia><poor diet><pre-k><pre-kindergarten><preschool><prevent><prevent obesity><preventing><primary care giver><primary caregiver><programs><prospective><recruit><risk for obesity><risk of obesity><saturated dietary fat><saturated dietary lipid><saturated fat><saturated lipid><science, technology, engineering and math research><science, technology, engineering and mathematics research><social role><success><sugar><theories><trait><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SHERYL O HUGHES

TEMPLE UNIV OF THE COMMONWEALTH, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$634,462

FY 2026

Project Title

Deconstructing food parenting approaches to obesity prevention for the highly food motivated child

Grant Number:

5R01DK132642-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

High levels of food motivation among young children are heritable, track over time, and associated with elevated risks of unhealthy eating and obesity. Despite significant growth of family-based obesity prevention efforts, the evidence base is remarkably scant on parenting highly food motivated chil...

Research Terms

<0-11 years old><Address><Authoritarianism><BMI><BMI percentile><BMI z-score><Basic Behavioral Science><Basic Research><Basic Science><Behavioral Research><Body mass index><Care Givers><Caregivers><Child><Child Rearing><Child Youth><Children (0-21)><Consumption><Diet Habits><Dietary Habits><Dietary intake><Dietary quality><Dimensions><Eating><Eating Behavior><Ecological momentary assessment><Equilibrium><Family><Food><Food Intake><Foundations><Generalized Growth><Goals><Growth><Healthy Eating><Heritability><Hyperphagia><Individual Differences><Intake><Intervention><Investigation><Knowledge><Light><Literature><Measures><Methods><Motivation><Nursery Schools><Obesity><Outcome><Overeating><Parenting><Parenting behavior><Parents><Photoradiation><Population Group><Prevention><Prevention Research><Proliferating><Prospective cohort><Quetelet index><Recommendation><Research><Risk><Role><STEM research><Specificity><Structure><Time><Tissue Growth><Unhealthy Diet><Weight><Work><adiposity><authoritarian><balance><balance function><childrearing><corpulence><design><designing><diet quality><dietary><dietary excess><eating habit><eating in absence of hunger><elementary school><evidence base><experience><feeding><goal oriented behavior><grade school><kids><motivated behavior><obesity prevention><obesity risk><ontogeny><parent><parent influence><parental influence><polyphagia><poor diet><pre-k><pre-kindergarten><preschool><prevent><prevent obesity><preventing><primary care giver><primary caregiver><programs><prospective><recruit><risk for obesity><risk of obesity><saturated dietary fat><saturated dietary lipid><saturated fat><saturated lipid><science, technology, engineering and math research><science, technology, engineering and mathematics research><social role><success><sugar><theories><trait><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RONALD A COHEN

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$628,834

FY 2026

Project Title

WISE II - Obesity and Type-2 Diabetes: Bariatric Surgery Effects on Brain Function

Grant Number:

5R01DK099334-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/25/2014

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The obesity epidemic is a major public health problem, contributing to various comorbid medical conditions, including diabetes, cardiovascular disease, and brain disturbances. The proposed project is designed to delineate mechanisms underlying the effects of severe obesity on brain health and cognit...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eric Porges

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$628,834

FY 2026

Project Title

WISE II - Obesity and Type-2 Diabetes: Bariatric Surgery Effects on Brain Function

Grant Number:

5R01DK099334-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/25/2014

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The obesity epidemic is a major public health problem, contributing to various comorbid medical conditions, including diabetes, cardiovascular disease, and brain disturbances. The proposed project is designed to delineate mechanisms underlying the effects of severe obesity on brain health and cognit...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

John B Williamson

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$628,834

FY 2026

Project Title

WISE II - Obesity and Type-2 Diabetes: Bariatric Surgery Effects on Brain Function

Grant Number:

5R01DK099334-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/25/2014

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The obesity epidemic is a major public health problem, contributing to various comorbid medical conditions, including diabetes, cardiovascular disease, and brain disturbances. The proposed project is designed to delineate mechanisms underlying the effects of severe obesity on brain health and cognit...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

STEPHEN ROBERT FARMER

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$625,033

FY 2026

Project Title

Deconstructing the diet-induced remodeling of adipose tissue

Grant Number:

5R01DK134534-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Obesity is a major risk factor for several metabolic diseases most notably diabetes and cardiovascular disease. During diet-induced obesity, visceral white adipose tissue (vWAT) responds to caloric excess through the recruitment of new fat cells (hyperplasia) and enlargement of exist...

Research Terms

<2aR phosphoprotein I><2ar peptide><Actins><Adhesion Plaques><Adipocytes><Adipose Cell><Adipose tissue><Adult-Onset Diabetes Mellitus><Anti-Obesity Agents><Anti-Obesity Drugs><Basal Transcription Factor><Basal transcription factor genes><Blood Vessels><Body Tissues><CD140a Antigens><CSAID-Binding Protein 1><CSAID-Binding Protein 2><CSBP2><Calories><Cancers><Cardiovascular Diseases><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Compartmentation><Cell Compartmentations><Cell Count><Cell Interaction><Cell Number><Cell Signaling><Cell-Extracellular Matrix><Cell-Matrix Adherens Junctions><Cell-to-Cell Interaction><Cells><Cellular Matrix><Chromatin><Chronic><Collagen Type VI><Consumption><Cytokine-Suppressive Antiinflammatory Drug-Binding Protein 1><Cytokine-Suppressive Antiinflammatory Drug-Binding protein 2><Cytoskeletal Gene><Cytoskeletal Proteins><Cytoskeletal System><Cytoskeleton><Data><Deposit><Deposition><Development><Diabetes Mellitus><Diet><Dysfunction><ECM><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Eta-1 protein><Eta-1-Op protein><Expression Signature><Extracellular Matrix><Extracellular Signal-Regulated Kinase Gene><Fat Cells><Fat progenitor cell><Fat stem cell><Fatty Tissue><Fibrosis><Focal Adhesions><Focal Contacts><Functional disorder><Gene Expression><Gene Expression Profile><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genetic Transcription><Goals><High Fat Diet><Hyperplasia><Hyperplastic><Hypertrophy><Hypoxia><Hypoxic><Immune><Immunes><In Vitro><Incidence><Inflammation><Inflammatory Infiltrate><Integrins><Integrins Extracellular Matrix><Intermediary Metabolism><Intima Collagen><Intracellular Communication and Signaling><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Lipocytes><MAP Kinase Gene><MAPK><MAPK14><MAPK14 Mitogen-Activated Protein Kinase><MAPK14 gene><MEKs><Macrophage><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Mechanical Stress><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolic dysfunction><Metabolism><Mitogen-Activated Protein Kinase 14><Mitogen-Activated Protein Kinase Gene><Mxi2><Mφ><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obese Mice><Obesity><Oxygen Deficiency><PDGF alpha Receptor><PDGF receptor α><PDGF-R-alpha><PDGFR-α><PDGFRα><Pathologic><Pathway interactions><Phenotype><Physiopathology><Platelet-Derived Growth Factor Receptor Alpha Polypeptide><Platelet-Derived Growth Factor alpha Receptor><Population><Production><Progenitor Cells><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Risk Factors><Role><SAPK2A><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Single-Nucleus Sequencing><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stress-Activated Protein Kinase 2A><T2 DM><T2D><T2DM><Thesaurismosis><Thinness><Time><Tissues><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Type VI (Intima) Collagen><Visceral><adipocyte progenitors><adipocyte stem cell><adipocyte-derived stem cell><adipogenesis><adipose><adipose derived stem cell><adipose progenitor><adipose stem cell><adipose tissue derived stem cell><adipose tissue stem cells><adiposity><adult onset diabetes><angiogenesis><anti-obesity compounds><anti-obesity medications><anti-obesity therapeutics><biological signal transduction><bone sialoprotein 1><bone sialoprotein I><calorie><cardiovascular disorder><cell type><cofactor><collagen 6><collagen Type 6><collagen VI><corpulence><design><designing><developmental><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><early T-lympocyte activation-1 protein><energy balance><epigenetically><fat derived stem cell><fibrogenesis><gene expression pattern><gene expression signature><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><intracellular skeleton><ketosis resistant diabetes><lipid biosynthesis><lipogenesis><malignancy><maturity onset diabetes><mechanical cue><mechanical signal><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><metabolism disorder><myocardin><neoplasm/cancer><ob/ob mouse><osteopontin><p38><p38 MAP Kinase><p38 MAPK Gene><p38 Mitogen Activated Protein Kinase><p38 Protein Kinase><p38 SAPK><p38-Alpha><p38Alpha><pandemic><pandemic disease><pathophysiology><pathway><platelet-derived growth factor receptor α><progenitor><progenitor cell fate><progenitor fate><programs><recruit><response><sNuc-Seq><scRNA sequencing><scRNA-seq><secreted phosphoprotein 1><senescence><senescent><sialoprotein 1><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single nucleus RNA-sequencing><single nucleus seq><single-cell RNA sequencing><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><social role><stem and progenitor cell fate><stem cell fate><stem cells><transcription factor><transcriptional profile><transcriptional signature><transcriptome sequencing><transcriptomic sequencing><type 2 DM><type II DM><type two diabetes><vascular><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MATTHEW D LAYNE

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$625,033

FY 2026

Project Title

Deconstructing the diet-induced remodeling of adipose tissue

Grant Number:

5R01DK134534-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Obesity is a major risk factor for several metabolic diseases most notably diabetes and cardiovascular disease. During diet-induced obesity, visceral white adipose tissue (vWAT) responds to caloric excess through the recruitment of new fat cells (hyperplasia) and enlargement of exist...

Research Terms

<2aR phosphoprotein I><2ar peptide><Actins><Adhesion Plaques><Adipocytes><Adipose Cell><Adipose tissue><Adult-Onset Diabetes Mellitus><Anti-Obesity Agents><Anti-Obesity Drugs><Basal Transcription Factor><Basal transcription factor genes><Blood Vessels><Body Tissues><CD140a Antigens><CSAID-Binding Protein 1><CSAID-Binding Protein 2><CSBP2><Calories><Cancers><Cardiovascular Diseases><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Compartmentation><Cell Compartmentations><Cell Count><Cell Interaction><Cell Number><Cell Signaling><Cell-Extracellular Matrix><Cell-Matrix Adherens Junctions><Cell-to-Cell Interaction><Cells><Cellular Matrix><Chromatin><Chronic><Collagen Type VI><Consumption><Cytokine-Suppressive Antiinflammatory Drug-Binding Protein 1><Cytokine-Suppressive Antiinflammatory Drug-Binding protein 2><Cytoskeletal Gene><Cytoskeletal Proteins><Cytoskeletal System><Cytoskeleton><Data><Deposit><Deposition><Development><Diabetes Mellitus><Diet><Dysfunction><ECM><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Eta-1 protein><Eta-1-Op protein><Expression Signature><Extracellular Matrix><Extracellular Signal-Regulated Kinase Gene><Fat Cells><Fat progenitor cell><Fat stem cell><Fatty Tissue><Fibrosis><Focal Adhesions><Focal Contacts><Functional disorder><Gene Expression><Gene Expression Profile><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genetic Transcription><Goals><High Fat Diet><Hyperplasia><Hyperplastic><Hypertrophy><Hypoxia><Hypoxic><Immune><Immunes><In Vitro><Incidence><Inflammation><Inflammatory Infiltrate><Integrins><Integrins Extracellular Matrix><Intermediary Metabolism><Intima Collagen><Intracellular Communication and Signaling><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Lipocytes><MAP Kinase Gene><MAPK><MAPK14><MAPK14 Mitogen-Activated Protein Kinase><MAPK14 gene><MEKs><Macrophage><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Mechanical Stress><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolic dysfunction><Metabolism><Mitogen-Activated Protein Kinase 14><Mitogen-Activated Protein Kinase Gene><Mxi2><Mφ><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obese Mice><Obesity><Oxygen Deficiency><PDGF alpha Receptor><PDGF receptor α><PDGF-R-alpha><PDGFR-α><PDGFRα><Pathologic><Pathway interactions><Phenotype><Physiopathology><Platelet-Derived Growth Factor Receptor Alpha Polypeptide><Platelet-Derived Growth Factor alpha Receptor><Population><Production><Progenitor Cells><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Risk Factors><Role><SAPK2A><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Single-Nucleus Sequencing><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stress-Activated Protein Kinase 2A><T2 DM><T2D><T2DM><Thesaurismosis><Thinness><Time><Tissues><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Type VI (Intima) Collagen><Visceral><adipocyte progenitors><adipocyte stem cell><adipocyte-derived stem cell><adipogenesis><adipose><adipose derived stem cell><adipose progenitor><adipose stem cell><adipose tissue derived stem cell><adipose tissue stem cells><adiposity><adult onset diabetes><angiogenesis><anti-obesity compounds><anti-obesity medications><anti-obesity therapeutics><biological signal transduction><bone sialoprotein 1><bone sialoprotein I><calorie><cardiovascular disorder><cell type><cofactor><collagen 6><collagen Type 6><collagen VI><corpulence><design><designing><developmental><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><early T-lympocyte activation-1 protein><energy balance><epigenetically><fat derived stem cell><fibrogenesis><gene expression pattern><gene expression signature><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><intracellular skeleton><ketosis resistant diabetes><lipid biosynthesis><lipogenesis><malignancy><maturity onset diabetes><mechanical cue><mechanical signal><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><metabolism disorder><myocardin><neoplasm/cancer><ob/ob mouse><osteopontin><p38><p38 MAP Kinase><p38 MAPK Gene><p38 Mitogen Activated Protein Kinase><p38 Protein Kinase><p38 SAPK><p38-Alpha><p38Alpha><pandemic><pandemic disease><pathophysiology><pathway><platelet-derived growth factor receptor α><progenitor><progenitor cell fate><progenitor fate><programs><recruit><response><sNuc-Seq><scRNA sequencing><scRNA-seq><secreted phosphoprotein 1><senescence><senescent><sialoprotein 1><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single nucleus RNA-sequencing><single nucleus seq><single-cell RNA sequencing><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><social role><stem and progenitor cell fate><stem cell fate><stem cells><transcription factor><transcriptional profile><transcriptional signature><transcriptome sequencing><transcriptomic sequencing><type 2 DM><type II DM><type two diabetes><vascular><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Shan Luo

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$616,930

FY 2026

Project Title

Effects of Maternal Diabetes on early brain development

Grant Number:

5R01DK137899-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary One in every five youth are living with obesity, placing them at increased risk for developing diabetes and cardiovascular disease. Identifying risk factors contributing to obesity is extremely critical so that prevention strategies can be taken early to mitigate the obesity risk. Ma...

Research Terms

<0-11 years old><2 year old><2 years of age><3 year old><3 years of age><Accounting><Adolescent obesity><Affect><Ammon Horn><Area><Behavioral Mechanisms><Big Data><BigData><Biochemical Pathway><Birth><Body Weight><Brain><Brain Mapping><Brain Nervous System><Brain region><Cardiovascular Diseases><Causality><Child><Child Youth><Children (0-21)><Classification><Cohort Studies><Cornu Ammonis><Country><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Analyses><Data Analysis><Data Set><Development><Diabetes Mellitus><Diffusion><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Early Intervention><Economic Burden><Encephalon><Etiology><Exposure to><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Future><Generalized Growth><Genetic><Genomics><Gestation><Goals><Growth><Health Care Costs><Health Costs><Hippocampus><Hypothalamic structure><Hypothalamus><Image><Individual><Infant><Intervention><Knowledge><Length><Life><Link><Maps><Measures><Mechanisms of Behavior and Behavior Change><Meta-Analysis><Metabolic><Metabolic Networks><Modeling><Multimodal Imaging><NIH><National Institutes of Health><Neurosciences><Obesity><Overweight><Parturition><Pathway interactions><Perinatal Exposure><Population><Pregnancy><Pregnancy in Diabetes><Pregnancy in Diabetics><Preventative strategy><Prevention strategy><Preventive strategy><Public Health><Reproducibility><Research Resources><Resources><Rest><Rewards><Risk><Risk Factors><Site><Structure><Surface><Systematics><Techniques><Testing><Thick><Thickness><Tissue Growth><Treatment Efficacy><Uncertainty><United States National Institutes of Health><Work><Youth><Youth 10-21><adiposity><age 2><age 2 years><age 3><age 3 years><aged 2 years><aged two years><behavior mechanism><brain abnormalities><brain based><cardiovascular disorder><causation><child adiposity><child obesity><childhood adiposity><childhood obesity><cognitive control><cohort><cohort research study><cohort survey><computer based prediction><corpulence><critical period><dMRI><data analysis pipeline><data harmonization><data interpretation><data processing pipeline><deep learning based model><deep learning model><design><designing><developmental><diabetes><diffused><diffuses><diffusing><diffusion tensor imaging><diffusions><disease causation><doubt><early childhood><exposed in utero><fMRI><fetal exposure><harmonized data><health economics><high risk><hippocampal><hypothalamic><image-based method><imaging><imaging method><imaging modality><in utero exposure><infancy><infantile><innovate><innovation><innovative><insight><intervention efficacy><intra-uterine environmental exposure><intrauterine environmental exposure><kids><later in life><later life><machine learned algorithm><machine learning algorithm><machine learning based algorithm><maternal adiposity><maternal diabetes><maternal obesity><multi-modal imaging><multi-modal neuro-imaging><multi-modality><multi-modality imaging><multimodal neuroimaging><multimodality><multimodality imaging><neonate><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><obese adolescents><obese children><obesity among adolescents><obesity development><obesity during adolescence><obesity during childhood><obesity in adolescence><obesity in adolescents><obesity in children><obesity risk><offspring><offspring obesity><ontogeny><pathway><pediatric obesity><predictive biological marker><predictive biomarkers><predictive marker><predictive modeling><predictive molecular biomarker><predictive signature><prenatal exposure><prenatally exposed><prepregnancy obesity><risk for obesity><risk of obesity><socio-economic><socio-economically><socioeconomically><socioeconomics><therapeutic efficacy><therapy efficacy><three year old><three years of age><two year old><two years of age><youngster><youth adiposity><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Deborah B Jacobvitz

UNIVERSITY OF TEXAS AT AUSTIN, AUSTIN, TX

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$609,354

FY 2026

Project Title

Mothers and CareGivers Investing in Children: A virtual intervention to support healthy growth in infants and toddlers

Grant Number:

5R01DK135947-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Childhood obesity remains a significant public health problem and obesity risk begins early in life. There is a need for accessible and comprehensive interventions focused on modifiable behaviors in infancy. This proposal is an efficacy trial for the virtual Mothers and CareGivers In...

Research Terms

<0-11 years old><3 year old><3 years of age><Active Follow-up><Adherence><Anthropometry><Application Context><Area><BMI><BMI percentile><BMI z-score><Behavior><Behavior assessment><Body Composition><Body Weight Changes><Body fat><Body mass index><Bottle feeding><Breast><Breast Feeding><Care Givers><Caregivers><Characteristics><Child><Child Youth><Children (0-21)><Clinical><Complementary Feeding><Cues><Curriculum><DEXA><DXA><Diet><Diet Habits><Dietary Habits><Dietary quality><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Eating><Educational Curriculum><Effectiveness><Enrollment><Family><Feeding behaviors><Food><Food Intake><Food Preferences><Fostering><Generalized Growth><Growth><Health><Healthy Eating><Hispanic><Individual><Infant><Informal Social Control><Ingestive Behavior><Intervention><Investments><Knowledge><Life><Life Cycle><Life Cycle Stages><Low income><Maintenance><Measurement><Measures><Mediation><Mental Depression><Modeling><Mothers><Negotiating><Negotiation><Newsletter><Nutrition><Obesity><PRISM framework><PRISM model><Participant><Pathway interactions><Patient Self-Report><Pattern><Persons><Practical Robust Implementation and Sustainability Model><Pragmatic, Robust Implementation and Sustainability Model><Prevalence><Public Health><Quetelet index><RE-AIM><Randomized><Randomized, Controlled Trials><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Research><Role><Safety><Self Regulation><Self-Report><Stress><Supplementary Feedings><Temperament><Testing><Text Messaging><Tissue Growth><Toddler><Underinsured><Uninsured><Visit><Weight><Weight Change><Work><active followup><adiposity><age 3><age 3 years><arm><attentional control><behavioral assessment><care giving><caregiving><child adiposity><child obesity><childhood adiposity><childhood obesity><contextual factors><corpulence><depression><design><designing><determine efficacy><diet choice><diet preference><diet quality><dietary choice><dietary guidelines><dietary preferences><diets><eat less><eating habit><eating in absence of hunger><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><efficacy trial><enroll><evaluate efficacy><examine efficacy><excessive weight gain><extreme weight gain><feeding><feeding-related behaviors><follow up><follow-up><followed up><followup><food choice><food insecure><food insecurity><food scarcity><healthy weight><implementation fidelity><improved><infancy><infantile><injury prevention><innovate><innovation><innovative><intervention effect><intervention program><kids><lesson plans><life course><low food security><lower income families><modifiable behavior><novel><nutrient intake activity><nutritional guideline><obese children><obesity during childhood><obesity in children><obesity prevention><obesity risk><ontogeny><pathway><pediatric obesity><pragmatic effectiveness trial><pragmatic trial><prevent><prevent obesity><preventing><primary care giver><primary caregiver><primary outcome><programs><quality of sleep><randomisation><randomization><randomized control trial><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><reduced eating><reduced food intake><risk for obesity><risk of obesity><satisfaction><serious weight gain><severe weight gain><short message service><skills><sleep quality><sms messaging><social role><successful intervention><texting><three year old><three years of age><trial design><virtual><virtual intervention><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Elizabeth Marie Widen

UNIVERSITY OF TEXAS AT AUSTIN, AUSTIN, TX

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$609,354

FY 2026

Project Title

Mothers and CareGivers Investing in Children: A virtual intervention to support healthy growth in infants and toddlers

Grant Number:

5R01DK135947-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Childhood obesity remains a significant public health problem and obesity risk begins early in life. There is a need for accessible and comprehensive interventions focused on modifiable behaviors in infancy. This proposal is an efficacy trial for the virtual Mothers and CareGivers In...

Research Terms

<0-11 years old><3 year old><3 years of age><Active Follow-up><Adherence><Anthropometry><Application Context><Area><BMI><BMI percentile><BMI z-score><Behavior><Behavior assessment><Body Composition><Body Weight Changes><Body fat><Body mass index><Bottle feeding><Breast><Breast Feeding><Care Givers><Caregivers><Characteristics><Child><Child Youth><Children (0-21)><Clinical><Complementary Feeding><Cues><Curriculum><DEXA><DXA><Diet><Diet Habits><Dietary Habits><Dietary quality><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Eating><Educational Curriculum><Effectiveness><Enrollment><Family><Feeding behaviors><Food><Food Intake><Food Preferences><Fostering><Generalized Growth><Growth><Health><Healthy Eating><Hispanic><Individual><Infant><Informal Social Control><Ingestive Behavior><Intervention><Investments><Knowledge><Life><Life Cycle><Life Cycle Stages><Low income><Maintenance><Measurement><Measures><Mediation><Mental Depression><Modeling><Mothers><Negotiating><Negotiation><Newsletter><Nutrition><Obesity><PRISM framework><PRISM model><Participant><Pathway interactions><Patient Self-Report><Pattern><Persons><Practical Robust Implementation and Sustainability Model><Pragmatic, Robust Implementation and Sustainability Model><Prevalence><Public Health><Quetelet index><RE-AIM><Randomized><Randomized, Controlled Trials><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Research><Role><Safety><Self Regulation><Self-Report><Stress><Supplementary Feedings><Temperament><Testing><Text Messaging><Tissue Growth><Toddler><Underinsured><Uninsured><Visit><Weight><Weight Change><Work><active followup><adiposity><age 3><age 3 years><arm><attentional control><behavioral assessment><care giving><caregiving><child adiposity><child obesity><childhood adiposity><childhood obesity><contextual factors><corpulence><depression><design><designing><determine efficacy><diet choice><diet preference><diet quality><dietary choice><dietary guidelines><dietary preferences><diets><eat less><eating habit><eating in absence of hunger><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><efficacy trial><enroll><evaluate efficacy><examine efficacy><excessive weight gain><extreme weight gain><feeding><feeding-related behaviors><follow up><follow-up><followed up><followup><food choice><food insecure><food insecurity><food scarcity><healthy weight><implementation fidelity><improved><infancy><infantile><injury prevention><innovate><innovation><innovative><intervention effect><intervention program><kids><lesson plans><life course><low food security><lower income families><modifiable behavior><novel><nutrient intake activity><nutritional guideline><obese children><obesity during childhood><obesity in children><obesity prevention><obesity risk><ontogeny><pathway><pediatric obesity><pragmatic effectiveness trial><pragmatic trial><prevent><prevent obesity><preventing><primary care giver><primary caregiver><primary outcome><programs><quality of sleep><randomisation><randomization><randomized control trial><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><reduced eating><reduced food intake><risk for obesity><risk of obesity><satisfaction><serious weight gain><severe weight gain><short message service><skills><sleep quality><sms messaging><social role><successful intervention><texting><three year old><three years of age><trial design><virtual><virtual intervention><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ERIC M STICE

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$605,651

FY 2026

Project Title

Effects of Processed Foods on Brain Reward Circuitry and Food Cue Learning

Grant Number:

5R01DK136030-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Obesity is the second leading cause of premature death. Consumption of ultra-processed foods is theorized to be a key cause of obesity. Ultra-processed foods are formulations of cheap industrial sources of dietary energy and nutrients plus additives such as fat, sugar, and flavors that enha...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KAREN R JONSCHER

UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OKLAHOMA CITY, OK

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$602,977

FY 2026

Project Title

Evaluating PQQ for preventing maternal obesity-induced fetal programming of juvenile NAFLD in Papio anubis

Grant Number:

5R01DK139443-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. NOTE: You must submit in Word format, not PDF, for eRA to update all the systems. Maternal obesity (MO) affects >60% of pregnancies in the US and is associated with fe...

Research Terms

<1 year of age><1 year old><21+ years old><Abdominal Delivery><Acceleration><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Affect><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Antioxidants><Anubis baboon><Ascorbic Acid><Attenuated><Automobile Driving><Baboons><Biochemical><Biological Markers><Blood Plasma><Blood Precursor Cell><Blood Serum><Blood flow><Blood monocyte><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><C section><CD14><CD14 gene><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cells Placenta-Tissue><Cesarean><Cesarean section><Chemotactic Cytokines><Cholesterol><Chromatin><Clinical><Coenzyme PQQ><Cord Blood><D-Glucose><DNA Methylation><Data><Defect><Dehydrogenases><Development><Dextrose><Diabetes Mellitus><Diathesis><Diet><Disease Marker><Disease susceptibility><Doguera baboon><Doppler Ultrasound><Dose><Drug Therapy><Dysfunction><Endotoxemia><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exhibits><Feces><Female><Fetal Liver><Fetus><Food Supplements><Functional Metagenomics><Functional disorder><GI commensal><GI microbiome><Gene Transcription><Genetic Transcription><Genus Hippocampus><Gestation><Glucose><HDL><HDL Lipoproteins><Health><Health Promotion><Heavy Lipoproteins><Hematopoietic Progenitor Cells><Hematopoietic stem cells><Hepatic Cells><Hepatic Disorder><Hepatic Parenchymal Cell><Hepatic Transplantation><Hepatocyte><High Density Lipoproteins><Histopathology><Homologous Chemotactic Cytokines><Human><Humulin R><Hypoxia><Hypoxic><IVGTT><Immune><Immune system><Immunes><Immunofluorescence><Immunofluorescence Immunologic><Immunologic Subtyping><Immunomodulation><Immunophenotyping><Impairment><In Vitro><Infant><Inflammation><Inflammatory><Insulin><Intercrines><Intermediary Metabolism><Interruption><Intervention><Intracellular Communication and Signaling><Kenya baboon><Kupffer Cells><LDL><LDL Lipoproteins><Large-Scale Sequencing><Link><Lipids><Liver><Liver Cells><Liver Grafting><Liver Transplant><Liver diseases><Low-Density Lipoproteins><Macrophage><Marrow monocyte><Measures><Mediator><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Metagenomics><Methoxatin><Mice><Mice Mammals><MicroRNAs><Mitochondria><Modeling><Modern Man><Molecular><Murine><Mus><Mφ><NAFLD><NHP models><Non-pharmacologic Therapy><Nonpharmacologic Intervention><Nonpharmacologic Therapy><Nonpharmacologic approach><Nonpharmacologic treatment><Normal Placentoma><Novolin R><Nutrient><Obesity><Olive Baboon><Oxidative Stress><Oxidoreductase><Oxidoreductase Gene><Oxygen Deficiency><PQQ Cofactor><Papio><Papio anubis><Pathway interactions><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiopathology><Placenta><Placenta Embryonic Tissue><Placentome><Plasma><Plasma Serum><Pre-Clinical Model><Prebeta-Lipoproteins><Preclinical Models><Predisposition><Pregnancy><Primates><Primates Mammals><Production><Property><Publishing><Pyrrolo-Quinoline Quinone><Pyrroloquinoline Quinone><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Recommendation><Reductases><Regular Insulin><Reticuloendothelial System, Serum, Plasma><Rodent><Rodentia><Rodents Mammals><SIS cytokines><Safety><Salutogenesis><Savanna Baboons><Seahorse><Serum><Signal Transduction><Signal Transduction Systems><Signaling><Stellate Sinusoidal Macrophage><Structure><Supplementation><Susceptibility><System><TBARs><Testing><Text><Therapeutic><Thesaurismosis><Thiobarbituric Acid Reactive Substances><Tissues><Transcription><Translations><Transmission><Umbilical Cord><Umbilical Cord Blood><Umbilical cord structure><Update><VIT C><VLDL><VLDL Lipoproteins><Venous><Very low density lipoprotein><Vitamin C><Vulnerable Populations><Woman><Youth><Youth 10-21><adiposity><adulthood><age 1><age 1 year><aged 1 year><aged one year><alpha-Lipoproteins><alter microbiome><attenuate><attenuates><beta-Lipoproteins><bio-markers><biologic marker><biological signal transduction><biomarker><blood cell progenitor><blood progenitor><blood stem cell><blood-forming stem cell><chemoattractant cytokine><chemokine><cofactor><commensal bacteria in the gastrointestinal tract><commensal bacteria in the gut><commensal bacteria in the intestine><corpulence><cytokine><density><developmental><diabetes><dietary antioxidant><diets><digestive tract microbiome><disease phenotype><disease risk><disorder risk><driving><drug intervention><drug treatment><enteric commensal><enteric microbiome><epigenetically><epigenomics><fat metabolism><fetal><fetal cord blood><fetal programming><gastrointestinal commensal><gastrointestinal microbiome><global gene expression><global transcription profile><gut commensal><gut microbiome><gut-associated microbiome><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic progenitor><hemopoietic stem cell><hepatic body system><hepatic disease><hepatic organ system><hepatopathy><hepatoprotection><hepatoprotective><high risk><immune modulation><immune regulation><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><improved><in utero><intestinal biome><intestinal commensal><intestinal microbiome><intravenous glucose tolerance><intravenous glucose tolerance test><juvenile><juvenile human><liability to disease><lipid metabolism><lipidomics><liver disorder><liver macrophage><liver transplantation><maternal GI tract><maternal adiposity><maternal gut><maternal obesity><metabolism disorder><metaproteomics><meter><methylation pattern><miRNA><microbial><microbiome><microbiome adaptation><microbiome alteration><microbiome community composition><microbiome composition><microbiome perturbation><microbiome species composition><microbiome structure><mitochondrial><monocyte><mother's gut><next generation><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-drug therapy><non-drug treatment><non-human primate><nonalcoholic fatty liver disease><nondrug therapy><nondrug treatment><nonhuman primate><nonhuman primate models><novel><obese mothers><obesity during pregnancy><obesity in pregnancy><offspring><offspring obesity><one year of age><one year old><pathophysiology><pathway><pediatric NAFLD><pediatric non-alcoholic fatty liver disease><pediatric nonalcoholic fatty liver disease><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><polyphenol><prevent><preventing><programs><promoting health><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stool><systemic inflammation><systemic inflammatory response><therapeutic evaluation><therapeutic testing><therapeutically effective><transcriptome><transcriptome sequencing><transcriptomic sequencing><translation><transmission process><trophoblast><vulnerable group><vulnerable individual><vulnerable people><western diet><western-style diet><western-type diet><youth age><♀>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DEAN MYERS

UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OKLAHOMA CITY, OK

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$602,977

FY 2026

Project Title

Evaluating PQQ for preventing maternal obesity-induced fetal programming of juvenile NAFLD in Papio anubis

Grant Number:

5R01DK139443-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. NOTE: You must submit in Word format, not PDF, for eRA to update all the systems. Maternal obesity (MO) affects >60% of pregnancies in the US and is associated with fe...

Research Terms

<1 year of age><1 year old><21+ years old><Abdominal Delivery><Acceleration><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Affect><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Antioxidants><Anubis baboon><Ascorbic Acid><Attenuated><Automobile Driving><Baboons><Biochemical><Biological Markers><Blood Plasma><Blood Precursor Cell><Blood Serum><Blood flow><Blood monocyte><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><C section><CD14><CD14 gene><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cells Placenta-Tissue><Cesarean><Cesarean section><Chemotactic Cytokines><Cholesterol><Chromatin><Clinical><Coenzyme PQQ><Cord Blood><D-Glucose><DNA Methylation><Data><Defect><Dehydrogenases><Development><Dextrose><Diabetes Mellitus><Diathesis><Diet><Disease Marker><Disease susceptibility><Doguera baboon><Doppler Ultrasound><Dose><Drug Therapy><Dysfunction><Endotoxemia><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exhibits><Feces><Female><Fetal Liver><Fetus><Food Supplements><Functional Metagenomics><Functional disorder><GI commensal><GI microbiome><Gene Transcription><Genetic Transcription><Genus Hippocampus><Gestation><Glucose><HDL><HDL Lipoproteins><Health><Health Promotion><Heavy Lipoproteins><Hematopoietic Progenitor Cells><Hematopoietic stem cells><Hepatic Cells><Hepatic Disorder><Hepatic Parenchymal Cell><Hepatic Transplantation><Hepatocyte><High Density Lipoproteins><Histopathology><Homologous Chemotactic Cytokines><Human><Humulin R><Hypoxia><Hypoxic><IVGTT><Immune><Immune system><Immunes><Immunofluorescence><Immunofluorescence Immunologic><Immunologic Subtyping><Immunomodulation><Immunophenotyping><Impairment><In Vitro><Infant><Inflammation><Inflammatory><Insulin><Intercrines><Intermediary Metabolism><Interruption><Intervention><Intracellular Communication and Signaling><Kenya baboon><Kupffer Cells><LDL><LDL Lipoproteins><Large-Scale Sequencing><Link><Lipids><Liver><Liver Cells><Liver Grafting><Liver Transplant><Liver diseases><Low-Density Lipoproteins><Macrophage><Marrow monocyte><Measures><Mediator><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Metagenomics><Methoxatin><Mice><Mice Mammals><MicroRNAs><Mitochondria><Modeling><Modern Man><Molecular><Murine><Mus><Mφ><NAFLD><NHP models><Non-pharmacologic Therapy><Nonpharmacologic Intervention><Nonpharmacologic Therapy><Nonpharmacologic approach><Nonpharmacologic treatment><Normal Placentoma><Novolin R><Nutrient><Obesity><Olive Baboon><Oxidative Stress><Oxidoreductase><Oxidoreductase Gene><Oxygen Deficiency><PQQ Cofactor><Papio><Papio anubis><Pathway interactions><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiopathology><Placenta><Placenta Embryonic Tissue><Placentome><Plasma><Plasma Serum><Pre-Clinical Model><Prebeta-Lipoproteins><Preclinical Models><Predisposition><Pregnancy><Primates><Primates Mammals><Production><Property><Publishing><Pyrrolo-Quinoline Quinone><Pyrroloquinoline Quinone><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Recommendation><Reductases><Regular Insulin><Reticuloendothelial System, Serum, Plasma><Rodent><Rodentia><Rodents Mammals><SIS cytokines><Safety><Salutogenesis><Savanna Baboons><Seahorse><Serum><Signal Transduction><Signal Transduction Systems><Signaling><Stellate Sinusoidal Macrophage><Structure><Supplementation><Susceptibility><System><TBARs><Testing><Text><Therapeutic><Thesaurismosis><Thiobarbituric Acid Reactive Substances><Tissues><Transcription><Translations><Transmission><Umbilical Cord><Umbilical Cord Blood><Umbilical cord structure><Update><VIT C><VLDL><VLDL Lipoproteins><Venous><Very low density lipoprotein><Vitamin C><Vulnerable Populations><Woman><Youth><Youth 10-21><adiposity><adulthood><age 1><age 1 year><aged 1 year><aged one year><alpha-Lipoproteins><alter microbiome><attenuate><attenuates><beta-Lipoproteins><bio-markers><biologic marker><biological signal transduction><biomarker><blood cell progenitor><blood progenitor><blood stem cell><blood-forming stem cell><chemoattractant cytokine><chemokine><cofactor><commensal bacteria in the gastrointestinal tract><commensal bacteria in the gut><commensal bacteria in the intestine><corpulence><cytokine><density><developmental><diabetes><dietary antioxidant><diets><digestive tract microbiome><disease phenotype><disease risk><disorder risk><driving><drug intervention><drug treatment><enteric commensal><enteric microbiome><epigenetically><epigenomics><fat metabolism><fetal><fetal cord blood><fetal programming><gastrointestinal commensal><gastrointestinal microbiome><global gene expression><global transcription profile><gut commensal><gut microbiome><gut-associated microbiome><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic progenitor><hemopoietic stem cell><hepatic body system><hepatic disease><hepatic organ system><hepatopathy><hepatoprotection><hepatoprotective><high risk><immune modulation><immune regulation><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><improved><in utero><intestinal biome><intestinal commensal><intestinal microbiome><intravenous glucose tolerance><intravenous glucose tolerance test><juvenile><juvenile human><liability to disease><lipid metabolism><lipidomics><liver disorder><liver macrophage><liver transplantation><maternal GI tract><maternal adiposity><maternal gut><maternal obesity><metabolism disorder><metaproteomics><meter><methylation pattern><miRNA><microbial><microbiome><microbiome adaptation><microbiome alteration><microbiome community composition><microbiome composition><microbiome perturbation><microbiome species composition><microbiome structure><mitochondrial><monocyte><mother's gut><next generation><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-drug therapy><non-drug treatment><non-human primate><nonalcoholic fatty liver disease><nondrug therapy><nondrug treatment><nonhuman primate><nonhuman primate models><novel><obese mothers><obesity during pregnancy><obesity in pregnancy><offspring><offspring obesity><one year of age><one year old><pathophysiology><pathway><pediatric NAFLD><pediatric non-alcoholic fatty liver disease><pediatric nonalcoholic fatty liver disease><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><polyphenol><prevent><preventing><programs><promoting health><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stool><systemic inflammation><systemic inflammatory response><therapeutic evaluation><therapeutic testing><therapeutically effective><transcriptome><transcriptome sequencing><transcriptomic sequencing><translation><transmission process><trophoblast><vulnerable group><vulnerable individual><vulnerable people><western diet><western-style diet><western-type diet><youth age><♀>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KAMAL RAHMOUNI

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$585,994

FY 2026

Project Title

Role of FGF21 Action in Hypothalamic Neurons in Obesity-Associated Hypertension

Grant Number:

5R01HL162773-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary / Abstract Hypertension affects one billion people and is a principal reversible risk factor for cardiovascular disease. Obesity which has become common in the US and throughout the world is a major cause of hypertension, but the mechanisms underlying the relationship between obesity...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amber Fyfe-Johnson

WASHINGTON STATE UNIVERSITY, PULLMAN, WA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$583,253

FY 2026

Project Title

Childhood Obesity: the role of the gut Microbiome, outdoor Time, and Stress(COMETS)

Grant Number:

5R01HL168373-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT One third of US children have overweight or obesity; children are developing obesity at higher rates than at any other time in human history. Social determinants of health (SDoH) are strong and especially intractable risk factors for childhood obesity, creating a structural ...

Research Terms

<0-11 years old><21+ years old><5 year old><5 years of age><Adult><Adult Human><Aeroseb-HC><Affect><Alimentary Canal><Application Context><Area><Assay><BMI><BMI percentile><BMI z-score><Behavior><Bioassay><Biological><Biological Assay><Biological Markers><Body mass index><Budgets><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cetacort><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Chronic stress><Communities><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Cost Effectiveness Analysis><Cost-Benefit Analysis><Country><Cross-Sectional Studies><Cross-Sectional Survey><Curriculum><Dermacort><Digestive Tract><Disease Frequency Surveys><Economic Income><Economical Income><Educational Curriculum><Effectiveness><Eldecort><Eligibility><Eligibility Determination><Enrollment><Environmental Factor><Environmental Risk Factor><Epidemiologic Research><Exhibits><Exposure to><Family><GI Tract><GI microbiome><Gastrointestinal Tract><Gastrointestinal tract structure><Green space><Health><Health Status Index><Health Status Indicators><Heart Vascular><History><Household><Human><Hydrocortisone><Hydrocortone><Hytone><Income><Individual><Individual Adjustment><Inequity><Influentials><Intervention><Investments><Learning><Life><Link><Location><Mediation><Mediator><Microbe><Modeling><Modern Man><NHLBI><National Heart, Lung, and Blood Institute><Natural experiment><Nature><Negotiating><Negotiation><Neighborhoods><Nursery Schools><Nutracort><Obesity><Obesity Epidemic><Outcome><Outcome Measure><Overweight><Performance><Persons><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Physical activity><Physiologic><Physiological><Play><Policies><Population><Prevention><Proctocort><Protocol><Protocol Screening><Protocols documentation><Public Health><Quetelet index><Recording of previous events><Research><Risk Factors><Role><Sample Size><Sampling><Socio-economic status><Socioeconomic Status><Socioeconomically disadvantaged><Soil><Spottings><Stress><Students><Testing><Time><Trees><Visit><Waiting Lists><adiposity><adulthood><age 5><age 5 years><alimentary tract><bio-markers><biologic><biologic marker><biomarker><build resilience><build resiliency><built environment><child adiposity><child obesity><childhood adiposity><childhood obesity><circulatory system><contextual factors><corpulence><cost benefit economics><cost benefit effectiveness><cost efficient analysis><cost-effective analysis><critical period><cross-sectional research study><develop resilience><develop resiliency><digestive canal><digestive tract microbiome><early childhood><economic security><economic self-sufficiency><economic stability><economic well-being><education access><enhance resilience><enhance resiliency><enroll><enteric microbiome><environmental risk><epidemiologic investigation><experiment><experimental research><experimental study><experiments><facilitate resilience><fecal sample><financial security><financial stability><financial well-being><five year old><five years of age><gastrointestinal microbiome><greenspace><gut microbiome><gut-associated microbiome><histories><improve resilience><improve resiliency><improved><incomes><increase resilience><increase resiliency><indexing><innovate><innovation><innovative><intestinal biome><intestinal microbiome><investigate epidemiology><kids><lesson plans><life span><lifespan><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><measurable outcome><metropolitan><microbial><microorganism><mortality><novel><obese children><obesigenic><obesity during childhood><obesity in children><obesity management><obesity prevention><obesogenic><outcome measurement><pediatric><pediatric obesity><pre-k><pre-kindergarten><preschool><prevent><prevent obesity><preventing><primary outcome><programs><promote resilience><promote resiliency><prospective><psychologic><psychological><recruit><resilience><resilience development><resilient><secondary outcome><social><social health determinants><social role><social structural><social structure><socio-economic disadvantage><socio-economic position><socio-economically disadvantaged><socio-economically underprivileged><socio-structural><socioeconomic disadvantage><socioeconomic position><socioeconomically underprivileged><sociostructural><stool sample><stool specimen><stress reduction><study epidemiology><survey epidemiology><urban environment><urban setting><waitlist><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Esther M Leerkes

UNIVERSITY OF NORTH CAROLINA GREENSBORO, GREENSBORO, NC

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$579,603

FY 2026

Project Title

Food and Non-Food Self-Regulation in Children's Obesity Risk: A Biopsychosocial Perspective

Grant Number:

5R01HD110470-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Childhood obesity remains a significant public health crisis. Most children with obesity are likely to remain obese as they mature and are at risk to experience significantly more lifelong physical and mental health issues, creating significant economic and public health consequences. Thus, identifi...

Research Terms

<0-11 years old><11 year old><11 years of age><12-20 years old><19 year old><19 years of age><2 year old><2 years of age><21+ years old><3 year old><3 years of age><5 year old><5 years of age><6-11 years old><Active Follow-up><Address><Adolescence><Adult><Adult Human><Adverse effects><Advocate><Appetite><Appetitive Behavior><Applied Research><Applied Science><BMI><BMI percentile><BMI z-score><Basic Research><Basic Science><Behavior><Behavioral><Biological><Body mass index><Buffers><Characteristics><Child><Child Rearing><Child Youth><Childhood><Children (0-21)><Collaborations><Complex><Data><Desire for food><Development><Dimensions><Discipline><Eating><Economics><Emotional><Endocrine Gland Secretion><Energy Expenditure><Energy Metabolism><Environmental Factor><Environmental Risk Factor><Ethnic Origin><Ethnicity><Food><Food Intake><Future><Health><Home><Home environment><Hormonal><Hormones><Individual><Infant><Inflammation><Influentials><Informal Social Control><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigators><Knowledge><Life><Life Style><Lifestyle><Longitudinal Studies><Longitudinal Surveys><Maternal Behavior><Measurement><Measures><Mental Health><Mental Hygiene><Methodology><Methods><Modeling><Morbid Obesity><Mothers><Multidisciplinary Collaboration><Multidisciplinary Research><NICHD><NIDDK><National Institute of Child Health and Human Development><National Institute of Diabetes and Digestive and Kidney Diseases><Nursery Schools><Nutritional Science><Obesity><Parent-Child Relations><Parent-Child Relationship><Parenting><Parenting behavior><Physiologic><Physiological><Prevalence><Preventative intervention><Prevention><Process><Psychological Health><Public Health><Public Policy><Quetelet index><Race><Races><Regulation><Research><Research Personnel><Researchers><Risk><Risk Factors><Role><Sampling><Satiation><Self Regulation><Severe obesity><Social Processes><Socio-economic status><Socioeconomic Status><Solid><Structure><Testing><Therapeutic Hormone><Time><Weight><Work><active followup><adiposity><adolescence (12-20)><adulthood><age 11><age 11 years><age 19><age 19 years><age 2><age 2 years><age 3><age 3 years><age 5><age 5 years><aged 2 years><aged two years><biologic><biopsychosocial><child adiposity><child obesity><childhood adiposity><childhood obesity><childrearing><computer based prediction><corpulence><cue reactivity><developmental><early childhood><eating cues><economic><eleven year old><eleven years of age><environmental risk><experience><extreme obesity><feeding><five year old><five years of age><follow up><follow-up><followed up><followup><food cues><homes><hunger cues><indexing><infancy><infantile><innovate><innovation><innovative><intervention for prevention><kids><long-term study><longitudinal outcome studies><longitudinal research study><middle childhood><multidisciplinary><nineteen year old><nineteen years old><nutrition science><obese children><obesigenic><obesity development><obesity during childhood><obesity in children><obesity intervention><obesity prevention><obesity risk><obesity therapy><obesity treatment><obesogenic><parent child interaction><parent offspring interaction><pediatric><pediatric obesity><physical conditioning><physical health><policy implication><pre-k><pre-kindergarten><predictive modeling><prenatal><preschool><prevent><prevent obesity><preventing><prevention intervention><preventional intervention strategy><preventive intervention><protective factors><psychologic><psychological><psychosocial><racial><racial background><racial origin><recruit><response><risk for obesity><risk of obesity><satiety><skills><social><social role><socio-economic position><socioeconomic position><three year old><three years of age><trait><two year old><two years of age><unborn><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALLISON Deborah FRYER

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$576,359

FY 2026

Project Title

Insulin increases nerve-mediated bronchoconstriction in obesity-related asthma

Grant Number:

5R01HL163087-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Obesity increases both the incidence and severity of asthma. Obesity-related asthma is associated with more frequent symptom exacerbations and hospitalizations, which respond poorly to current asthma medications leading to increased healthcare costs and decreased quality of life. The...

Research Terms

<3-D><3-Dimensional><3D><5-HT><5-Hydroxytryptamine><5HT><Acetylcholine><Acute><Afferent Neurons><Airway Hyper-responsiveness><Animals><Anti-Cholinergics><Anticholinergic Agents><Anticholinergics><Architecture><Asthma><Body Tissues><Bronchial Asthma><Bronchial Constriction><Bronchial-Dilating Agents><Bronchoconstriction><Bronchodilator Agents><Bronchodilators><Cell Communication and Signaling><Cell Signaling><Chimera Protein><Chimeric Proteins><Common Rat Strains><Computer Assisted><Cranial Nerve X><Data><Disease Management><Disorder Management><Drugs><Engineering / Architecture><Enteramine><Epithelium><Fusion Protein><Goals><Health Care Costs><Health Costs><Hippophaine><Hospital Admission><Hospitalization><Human><Humulin R><Hyperinsulinemia><Hyperinsulinism><In Vitro><In vivo analysis><Incidence><Inhalation><Inhaling><Insulin><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin-Dependent Tyrosine Protein Kinase><Intracellular Communication and Signaling><Involuntary Muscle><Light><Link><Lung><Lung Respiratory System><M2 receptor><M3 receptor><Measures><Mediating><Medication><Medicine><Methods><Mice><Mice Mammals><Modern Man><Molecular><Murine><Mus><Muscarinic M2 Receptor><Muscarinic M3 Receptor><Muscle Cell Contraction><Muscle Contraction><Muscular Contraction><Nerve><Nerve Cells><Nerve Transmitter Substances><Nerve Unit><Neural Cell><Neurocyte><Neuronal Dysfunction><Neurons><Neurotransmitters><Novolin R><Obese Mice><Obesity><Pathway interactions><Patients><Peripheral><Pharmaceutical Preparations><Photoradiation><Pneumogastric Nerve><Prevalence><Prevention><QOL><Quality of life><Rat><Rats Mammals><Rattus><Reflex><Reflex action><Regular Insulin><Research><Respiratory Epithelium><Role><STZ><Sensory><Sensory Neurons><Serotonin><Severities><Severity of illness><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Smooth Muscle><Streptozocin><Streptozotocin><Structure><Structure of respiratory epithelium><Symptoms><Techniques><Tenth Cranial Nerve><Testing><Tissues><Trachea><Trachea Proper><Transgenic Mice><Treatment Cost><Vagotomy><Vagus Nerve><Vagus nerve structure><Zanosar><adiposity><afferent nerve><airway epithelium><airway hyper-reactivity><airway hyperactivity><airway hyperreactivity><airway hyperresponsiveness><airway hypersensitivity><airway smooth muscle><arm><asthmatic><biological signal transduction><cholinergic><computer aided><corpulence><density><disease severity><drug/agent><effective therapy><effective treatment><in vivo evaluation><in vivo testing><innervation><innovate><innovation><innovative><lumen dilator><nerve supply><neural><neural control><neural dysfunction><neural regulation><neuromodulation><neuromodulatory><neuronal><neuroregulation><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><ob/ob mouse><obese asthma><obese individuals><obese patients><obese people><obese person><obese population><obese subjects><obesity intervention><obesity therapy><obesity treatment><obesity-associated asthma><obesity-related asthma><optogenetics><pathway><patients with obesity><prevent><preventing><receptor expression><reconstruction><respiratory smooth muscle><respiratory tract epithelium><sensory nerve><social role><three dimensional><windpipe>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Zhenying Nie

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$576,359

FY 2026

Project Title

Insulin increases nerve-mediated bronchoconstriction in obesity-related asthma

Grant Number:

5R01HL163087-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Obesity increases both the incidence and severity of asthma. Obesity-related asthma is associated with more frequent symptom exacerbations and hospitalizations, which respond poorly to current asthma medications leading to increased healthcare costs and decreased quality of life. The...

Research Terms

<3-D><3-Dimensional><3D><5-HT><5-Hydroxytryptamine><5HT><Acetylcholine><Acute><Afferent Neurons><Airway Hyper-responsiveness><Animals><Anti-Cholinergics><Anticholinergic Agents><Anticholinergics><Architecture><Asthma><Body Tissues><Bronchial Asthma><Bronchial Constriction><Bronchial-Dilating Agents><Bronchoconstriction><Bronchodilator Agents><Bronchodilators><Cell Communication and Signaling><Cell Signaling><Chimera Protein><Chimeric Proteins><Common Rat Strains><Computer Assisted><Cranial Nerve X><Data><Disease Management><Disorder Management><Drugs><Engineering / Architecture><Enteramine><Epithelium><Fusion Protein><Goals><Health Care Costs><Health Costs><Hippophaine><Hospital Admission><Hospitalization><Human><Humulin R><Hyperinsulinemia><Hyperinsulinism><In Vitro><In vivo analysis><Incidence><Inhalation><Inhaling><Insulin><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin-Dependent Tyrosine Protein Kinase><Intracellular Communication and Signaling><Involuntary Muscle><Light><Link><Lung><Lung Respiratory System><M2 receptor><M3 receptor><Measures><Mediating><Medication><Medicine><Methods><Mice><Mice Mammals><Modern Man><Molecular><Murine><Mus><Muscarinic M2 Receptor><Muscarinic M3 Receptor><Muscle Cell Contraction><Muscle Contraction><Muscular Contraction><Nerve><Nerve Cells><Nerve Transmitter Substances><Nerve Unit><Neural Cell><Neurocyte><Neuronal Dysfunction><Neurons><Neurotransmitters><Novolin R><Obese Mice><Obesity><Pathway interactions><Patients><Peripheral><Pharmaceutical Preparations><Photoradiation><Pneumogastric Nerve><Prevalence><Prevention><QOL><Quality of life><Rat><Rats Mammals><Rattus><Reflex><Reflex action><Regular Insulin><Research><Respiratory Epithelium><Role><STZ><Sensory><Sensory Neurons><Serotonin><Severities><Severity of illness><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Smooth Muscle><Streptozocin><Streptozotocin><Structure><Structure of respiratory epithelium><Symptoms><Techniques><Tenth Cranial Nerve><Testing><Tissues><Trachea><Trachea Proper><Transgenic Mice><Treatment Cost><Vagotomy><Vagus Nerve><Vagus nerve structure><Zanosar><adiposity><afferent nerve><airway epithelium><airway hyper-reactivity><airway hyperactivity><airway hyperreactivity><airway hyperresponsiveness><airway hypersensitivity><airway smooth muscle><arm><asthmatic><biological signal transduction><cholinergic><computer aided><corpulence><density><disease severity><drug/agent><effective therapy><effective treatment><in vivo evaluation><in vivo testing><innervation><innovate><innovation><innovative><lumen dilator><nerve supply><neural><neural control><neural dysfunction><neural regulation><neuromodulation><neuromodulatory><neuronal><neuroregulation><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><ob/ob mouse><obese asthma><obese individuals><obese patients><obese people><obese person><obese population><obese subjects><obesity intervention><obesity therapy><obesity treatment><obesity-associated asthma><obesity-related asthma><optogenetics><pathway><patients with obesity><prevent><preventing><receptor expression><reconstruction><respiratory smooth muscle><respiratory tract epithelium><sensory nerve><social role><three dimensional><windpipe>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David Andrew Hill

CHILDREN'S HOSP OF PHILADELPHIA, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$566,515

FY 2026

Project Title

Impact of Obesity on Lung Macrophage Metabolism and Inflammation

Grant Number:

5R01HL162715-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2022

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Obesity increases the risk of developing asthma in children and adults, and obesity-associated asthma (OAA) is often more severe and more difficult to treat than atopic asthma. These poor clinical outcomes may stem from OAA’s distinct immunopathology that includes difference...

Research Terms

<(TNF)-α><21+ years old><ASCVD><Address><Adipose tissue><Adopted><Adult><Adult Human><Allergic asthma><Apoptosis-Related Cysteine Protease Caspase 1><Asthma><Asthma in Children><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Biologic Models><Biological Models><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Body Tissues><Bronchial Asthma><Bronchioalveolar Lavage><Bronchoalveolar Lavage><Bronchopulmonary Lavage><CASP-1><CASP1><CASP1 gene><Cachectin><Caspase-1><Caspase-1 Gene><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Characteristics><Childhood><Childhood Asthma><Clinical><Collaborations><Culture Techniques><Data><Deposit><Deposition><Development><Drugs><Event><Extrinsic asthma><Fatty Acids><Fatty Tissue><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Future><Genetic><Grant><Human><ICE Protease><IL-1 alpha><IL-1 beta Convertase><IL-1 beta-Converting Enzyme><IL-1-a><IL-1A><IL-1BC><IL-1alpha><IL-1b Converting Enzyme><IL-1α><IL1-Alpha><IL1-α><IL1A Protein><IL1B-Convertase><IL1BC><IL1BCE><IL1F1><Immune><Immune response><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><In Vitro><Inflammasome><Inflammation><Inflammation Mediators><Inflammatory><Interleukin 1-B Converting Enzyme><Interleukin 1-Beta Convertase><Interleukin 1alpha><Interleukin-1 Beta Converting Enzyme><Interleukin-1 Converting Enzyme><Interleukin-1 alpha><Intermediary Metabolism><Intracellular Communication and Signaling><Knowledge><Leanness><Lipids><Lung><Lung Inflammation><Lung Lavage><Lung Parenchyma><Lung Respiratory System><Lung Tissue><Macrophage><Macrophage Activation><Macrophage-Derived TNF><Marrow Neutrophil><Measures><Mediating><Medication><Metabolic><Metabolic Pathway><Metabolic Processes><Metabolism><Mice><Mice Mammals><Model System><Modeling><Modern Man><Monocyte-Derived TNF><Murine><Mus><Mφ><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Obese Mice><Obesity><Obesity associated disease><Obesity related disease><Octadecanoates><Outcome><Pathogenesis><Pathway interactions><Patients><Pediatric asthma><Pharmaceutical Preparations><Phenotype><Pneumonitis><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Population><Preinterleukin 1 Alpha><Preventive><Process><Proteins><Publishing><Pulmonary Inflammation><RNA Seq><RNA sequencing><RNAseq><Reporter><Research Resources><Resources><Risk><Sampling><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Societies><Stearates><Steatohepatitis><Stimulus><Structure of parenchyma of lung><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Techniques><Testing><Therapeutic><Thinness><Tissues><Translating><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Work><adipose><adiposity><adulthood><airway epithelium inflammation><airway inflammation><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><atopic asthma><biological signal transduction><bronchiolar alveolar lavage><bronchopulmonary lavage therapy><corpulence><developmental><drug/agent><extrinsic allergic asthma><flow cytophotometry><host response><immune system response><immunopathology><immunoresponse><in vivo><inflammatory lung disease><inflammatory mediator><innovate><innovation><innovative><insight><lipidome><lipidomics><mouse model><murine model><neutrophil><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><ob/ob mouse><obese asthma><obese individuals><obese people><obese person><obese population><obese subjects><obesity-associated asthma><obesity-related asthma><pathway><pediatric><programs><respiratory inflammation><respiratory tract inflammation><response><stem><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic agent development><therapeutic development><transcriptome sequencing><transcriptomic sequencing><transcriptomics><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Matthew S Rodeheffer

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$562,800

FY 2026

Project Title

Defining the role of an endothelial-adipocyte precursor axis in adipocyte hyperplasia

Grant Number:

5R01DK132563-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/22/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Obesity, which is defined as the excess accumulation of white adipose tissue (WAT) is associated with the development of numerous metabolic, inflammatory, and cardiovascular derangements. However, it is the accumulation of visceral adipose (VWAT) that is associated with metabolic di...

Research Terms

<21+ years old><ARO><ARO1><Adipocyte precursor><Adipocytes><Adipose Cell><Adipose tissue><Adult><Adult Human><Aromatase><Biology><CPV1><CYAR><CYP 19><CYP19><CYP19A1><CYP19A1 gene><Cancers><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Communication and Signaling><Cell Signaling><Classification><Cytochrome P-450 CYP19><Cytochrome P450 19><Cytochrome P450 19A1><Data><Development><Diabetes Mellitus><Disease><Disorder><Endothelial Cells><Endothelium><Estrogen Synthase><Estrogen Synthetase><Estrogen decline><Estrogens><Estrone sulfotransferase><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Female><Glucocorticoid Receptor><Glucocorticoids><Gonadal Steroid Hormones><HPA axis><Heart Vascular><Hyperplasia><Hyperplastic><Imaging Procedures><Imaging Technics><Imaging Techniques><Inflammatory><Intracellular Communication and Signaling><KO mice><Knock-out Mice><Knockout Mice><Link><Lipocytes><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Mice><Mice Mammals><Modeling><Molecular><Murine><Mus><Null Mouse><Obesity><Obesity associated disease><Obesity related disease><Oophorectomy><Ovariectomy><P-450AROM><P450AROM><Pathology><Pathway interactions><Pattern><Play><Population><Preadipocytes><Precursor to adipocyte><Process><Production><Public Health><Receptor Signaling><Regulation><Role><Sex Hormones><Sex Steroid Hormones><Signal Transduction><Signal Transduction Systems><Signaling><Systematics><Therapeutic Estrogen><Thesaurismosis><Visceral><Visceral fat><Work><adipogenesis><adipose><adiposity><adulthood><biological signal transduction><cardiovascular disorder><circulatory system><corpulence><decline in estrogen><decrease estrogen><decrease in estrogen><developmental><diabetes><estrogen sulfotransferase><fat cell precursor><female gonadectomy><gonadal steroids><hypothalamic-pituitary-adrenal (HPA) axis><hypothalamic-pituitary-adrenal axis><hypothalmus-pituitary-adrenal axis><lipid biosynthesis><lipogenesis><male><malignancy><metabolism disorder><multiplexed imaging><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><obesigenic><obesity development><obesogenic><pathway><reduced estrogen><response><scRNA sequencing><scRNA-seq><sex><sex steroid><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><subcutaneous><subdermal><white adipose tissue><yellow adipose tissue><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PETER J TONTONOZ

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$553,800

FY 2026

Project Title

Lipid storage and utilization in physiology and obesity

Grant Number:

5R01DK136150-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT A major goal of our laboratory is to delineate regulatory mechanisms that control adipocyte development and systemic physiology in obesity and diabetes. This proposal will address a new regulatory pathway involved in adipose tissue adipose depot-specific energy expenditure. Understanding h...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Orlando Paul Simonetti

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$549,267

FY 2026

Project Title

Development and validation of cardiovascular MRI techniques on a low-field, ultra-wide bore system to assess patients with severe obesity

Grant Number:

5R01HL161618-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract Obesity has reached epidemic proportions in the USA, with more than 40% of the population classified as obese (body mass index (BMI) > 30 kg/m2), and nearly 10% as severely obese (BMI > 40 kg/m2). Cardiovascular disease (CVD), especially heart failure, is highly associated w...

Research Terms

<21+ years old><Accuracy of Diagnosis><Address><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><American Heart Association><Apoplexy><Artifacts><BMI><BMI percentile><BMI z-score><Body mass index><Brain Vascular Accident><Breathing><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Diagnostic Technics><Cardiovascular Diagnostic Techniques><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cell Communication and Signaling><Cell Signaling><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Clinical Management><Compensation><Computed Tomography><Development><Diagnostic><Diagnostic Imaging><Diameter><Dyslipidemias><Echocardiogram><Echocardiography><Epidemic><Equipment><Face><Fatty Tissue><Functional impairment><General Radiology><Goals><Health Care><Heart Diseases><Heart Muscle tissue><Heart Vascular><Heart failure><Hispanic male><Hispanic men><Hypertension><Image><Image Enhancement><Incidence><Individual><Institution><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Link><MR Imaging><MR Tomography><MRI><MRI biomarker><MRI marker><MRIs><Machine Learning><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Modality><Morbid Obesity><Morphologic artifacts><Myocardial tissue><NIDDM><NMR Imaging><NMR Tomography><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Magnetic Resonance Imaging><Obesity><Obesity Epidemic><Outcome><Patients><Physiologic><Physiologic pulse><Physiological><Population><Prevalence><Prognosis><Protocol><Protocols documentation><Pulse><Quetelet index><Radiation><Radiation Dose><Radiation Dose Unit><Radiology><Radiology Specialty><Reference Standards><Reporting><Reproducibility><Respiratory Aspiration><Respiratory Inspiration><Risk><Risk Factors><SPECT><SPECT imaging><Safety><Scanning><Severe obesity><Severities><Signal Transduction><Signal Transduction Systems><Signaling><Single-Photon Emission-Computed Radionuclide Tomography><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><Structure><Symptoms><System><Systematics><T2 DM><T2D><T2DM><Techniques><Testing><Tomodensitometry><Transthoracic Echocardiography><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><Validation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Walking><Weight><Work><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><Zeugmatography><absorption><accurate diagnosis><adipose><adiposity><adult onset diabetes><adulthood><attenuation><biological signal transduction><biomedical implant><black female><black women><brain attack><cardiac MRI><cardiac failure><cardiac magnetic resonance imaging><cardiovascular disease diagnosis><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder diagnosis><cardiovascular disorder risk><cardiovascular imaging><catscan><cerebral vascular accident><cerebrovascular accident><circulatory system><clinical care><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><corpulence><data acquisition><data acquisitions><de-noising><death risk><denoising><design><designing><determine efficacy><developmental><diagnostic ability><diagnostic accuracy><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><experience><extreme obesity><faces><facial><flexibility><flexible><head-to-head analysis><head-to-head comparison><healthy volunteer><heart disorder><heart sonography><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><image construction><image generation><image reconstruction><image-based method><imaging><imaging method><imaging modality><imaging system><implant device><implantable device><indwelling device><innovate><innovation><innovative><inspiration><interest><ketosis resistant diabetes><life-time risk><lifetime risk><machine based learning><magnetic field><magnetic resonance imaging biomarker><magnetic resonance imaging marker><maturity onset diabetes><mortality risk><non-contrast CT><non-invasive imaging><noncontrast CT><noncontrast computed tomography><noninvasive imaging><novel><obese patients><patients with obesity><prognostic ability><prognostic power><prognostic utility><prognostic value><reconstruction><single photon emission computed tomography><statistics><stroked><strokes><tool><type 2 DM><type II DM><type two diabetes><ultrasound><validations><weights><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Arta Monir Monjazeb

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$539,696

FY 2026

Project Title

The Impact of Obesity on Radiotherapy Anti-Tumor Effects

Grant Number:

5R01CA240751-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Obesity has reached pandemic levels in the United States and will soon surpass smoking as the number one cause of preventable cancer. Understanding how to best treat obese cancer patients is a critical unmet need. Preclinical data from our lab show increased resistance to radiotherapy (RT) ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael J Daniels

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$531,474

FY 2026

Project Title

Bayesian machine learning for complex missing data and causal inference with a focus on cardiovascular and obesity studies

Grant Number:

5R01HL166324-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary This proposal will develop Bayesian machine learning approaches via Bayesian nonparametrics (BNP) to handle nonignorable missingness (in outcomes and covariates) and conduct causal inference for electronic health records (EHRs), to address missingness in multivariate longitudinal dat...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

YUGUANG SHI

UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, SAN ANTONIO, TX

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$528,581

FY 2026

Project Title

Cellular mechanisms of NLRP3 activation by ALCAT1 in diet-induced obesity

Grant Number:

5R01DK133463-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/19/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity causes chronic “sterile” inflammation, which is implicated in insulin resistance and other metabolic complications. NLRP3 (NLR family pyrin domain containing 3) is an intracellular sensor for various “danger” signals from microbial infection and metabolic stress. Activation of NLRP3 inflamma...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MATTHEW LEBOWITZ

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$527,164

FY 2026

Project Title

GENETIC ATTRIBUTIONS AND PERCEPTIONS OF OBESITY

Grant Number:

5R01HG012868-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/20/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity is widespread in the United States and is a risk factor for chronic illness, impaired quality of life, and mortality. While increased rates of obesity are most plausibly attributed to social, economic, and environmental factors, genetic explanations for obesity have often been emphasized. Th...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rebecca L Pearl

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$527,164

FY 2026

Project Title

GENETIC ATTRIBUTIONS AND PERCEPTIONS OF OBESITY

Grant Number:

5R01HG012868-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/20/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity is widespread in the United States and is a risk factor for chronic illness, impaired quality of life, and mortality. While increased rates of obesity are most plausibly attributed to social, economic, and environmental factors, genetic explanations for obesity have often been emphasized. Th...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CAROLYN M TUCKER

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$527,164

FY 2026

Project Title

GENETIC ATTRIBUTIONS AND PERCEPTIONS OF OBESITY

Grant Number:

5R01HG012868-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/20/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity is widespread in the United States and is a risk factor for chronic illness, impaired quality of life, and mortality. While increased rates of obesity are most plausibly attributed to social, economic, and environmental factors, genetic explanations for obesity have often been emphasized. Th...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andres Cardenas

UNIVERSITY OF CALIFORNIA BERKELEY, BERKELEY, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$526,536

FY 2026

Project Title

Common and Distinct Influences of Prenatal and Postnatal Early-Life Adversity on Epigenomic Trajectories in Mexican American Children

Grant Number:

5R01MD016595-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/13/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Childhood obesity is a growing public health epidemic that is disproportionally affecting Hispanic children and associated with morbidity and downstream health disparities. Early-life adversity and childhood psychosocial stressors have been shown to contribute to obesity risk, with s...

Research Terms

<0-11 years old><12-20 years old><14 year old><14 years of age><18 year old><18 years of age><2 year old><2 years of age><Acceleration><Address><Adolescence><Affect><Aging><Biological><Biological Markers><Biological Testing><Birth><Blood><Blood Reticuloendothelial System><Body Tissues><California><Candidate Disease Gene><Candidate Gene><Cell Components><Cell Differentiation><Cell Differentiation process><Cell Lineage><Cell Structure><Cellular Structures><Chicanas><Chicanos><Child><Child Youth><Childhood><Children (0-21)><Chronic><Communities><Cues><DNA Markers><DNA Methylation><DNA biomarkers><Data><Developing fetus><Development><Disease><Disorder><Embryo Development><Embryogenesis><Embryonic Development><Environment><Epidemic><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Face><Fetal Development><Future><Gene Expression><Genes><Genetic><Genotype><Goals><GrimAge clock><Hannum clock><Health><Hispanic><Horvath clock><Household><Immune system><Individual><Individuals from minority><Individuals of minority><Inflammatory><Latine><Latinx><Life><Longitudinal Studies><Longitudinal Surveys><Low income><Measurement><Measures><Mediating><Mediation><Mediator><Mendelian randomization><Metabolic><Methods><Methylation><Mexican Americans><Minority><Minority Groups><Minority People><Minority Population><Minority individual><Modeling><Morbidity><Mothers><Negotiating><Negotiation><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Obesity><Obesity Epidemic><Overweight><Parturition><Pathway interactions><Pattern><Phase><PhenoAge clocks><Physiologic><Physiological><Predisposition><Prevalence><Psychosocial Factor><Public Health><RNA Seq><RNA sequencing><RNAseq><Reporting><Research><Risk><Risk Factors><Role><Salinas Valley><Sampling><Social Environment><Statistical Methods><Susceptibility><Testing><Tissues><Transcriptional Control><Transcriptional Regulation><Variant><Variation><Writing><accelerated epigenetic age><accelerated epigenetic aging><accelerated pace of epigenetic aging><acceleration in epigenetic age><adiposity><adolescence (12-20)><age 14><age 14 years><age 18><age 18 years><age 2><age 2 years><age clock><aged 2 years><aged two years><aging biological marker><aging biomarker><aging clocks><aging induced epigenetic change><aging marker><aging-associated epigenetic change><aging-related epigenetic change><bio-markers><biologic><biologic marker><biological adaptation to stress><biomarker><cellular differentiation><child adiposity><child obesity><childhood adiposity><childhood obesity><clock measuring biological age><clock measuring biological aging><clock of biological aging><cohort><corpulence><developmental><disparities in race><disparity due to race><disparity in health><early adversity><early biomarkers><early childhood><early childhood adversity><early detection biomarkers><early detection markers><early life adversity><eighteen year old><eighteen years of age><epigenetic age clocks><epigenetic aging><epigenetic biomarker><epigenetic clock><epigenetic marker><epigenetic mechanisms in aging><epigenetic modifications in aging><epigenetic molecular clocks><epigenetic regulation of aging><epigenetically><epigenome><epigenomics><faces><facial><faster epigenetic aging><faster rates of epigenetic aging><fetal><fourteen year old><fourteen years of age><health assessment><health disparity><increased epigenetic age><increased epigenetic aging><increased rates of epigenetic aging><inequality due to race><inequity due to race><kids><long-term study><longitudinal outcome studies><longitudinal research study><machine learning based method><machine learning method><machine learning methodologies><methylation biomarker><methylation clock><methylation marker><methylation pattern><methylome><minority communities><novel><obese children><obesity during childhood><obesity in children><obesity risk><offspring><pace of aging><pace of biological aging><pathway><pediatric><pediatric obesity><post-natal period><postnatal><postnatal period><prenatal><prenatal influence><prenatal screening><prenatal testing><programs><prospective><psychosocial stresses><psychosocial stressors><psychosocial variables><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><rapid epigenetic aging><rate of aging><rate of biological aging><reactioncrisis><response><risk for obesity><risk of obesity><social><social adversity><social climate><social context><social role><socioenvironment><socioenvironmental><speed of aging><speed of the aging><statistic methods><stress response><stressreaction><stressor><transcriptome sequencing><transcriptomic sequencing><transcriptomics><two year old><two years of age><unborn><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Julianna Deardorff

UNIVERSITY OF CALIFORNIA BERKELEY, BERKELEY, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$526,536

FY 2026

Project Title

Common and Distinct Influences of Prenatal and Postnatal Early-Life Adversity on Epigenomic Trajectories in Mexican American Children

Grant Number:

5R01MD016595-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/13/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Childhood obesity is a growing public health epidemic that is disproportionally affecting Hispanic children and associated with morbidity and downstream health disparities. Early-life adversity and childhood psychosocial stressors have been shown to contribute to obesity risk, with s...

Research Terms

<0-11 years old><12-20 years old><14 year old><14 years of age><18 year old><18 years of age><2 year old><2 years of age><Acceleration><Address><Adolescence><Affect><Aging><Biological><Biological Markers><Biological Testing><Birth><Blood><Blood Reticuloendothelial System><Body Tissues><California><Candidate Disease Gene><Candidate Gene><Cell Components><Cell Differentiation><Cell Differentiation process><Cell Lineage><Cell Structure><Cellular Structures><Chicanas><Chicanos><Child><Child Youth><Childhood><Children (0-21)><Chronic><Communities><Cues><DNA Markers><DNA Methylation><DNA biomarkers><Data><Developing fetus><Development><Disease><Disorder><Embryo Development><Embryogenesis><Embryonic Development><Environment><Epidemic><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Face><Fetal Development><Future><Gene Expression><Genes><Genetic><Genotype><Goals><GrimAge clock><Hannum clock><Health><Hispanic><Horvath clock><Household><Immune system><Individual><Individuals from minority><Individuals of minority><Inflammatory><Latine><Latinx><Life><Longitudinal Studies><Longitudinal Surveys><Low income><Measurement><Measures><Mediating><Mediation><Mediator><Mendelian randomization><Metabolic><Methods><Methylation><Mexican Americans><Minority><Minority Groups><Minority People><Minority Population><Minority individual><Modeling><Morbidity><Mothers><Negotiating><Negotiation><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Obesity><Obesity Epidemic><Overweight><Parturition><Pathway interactions><Pattern><Phase><PhenoAge clocks><Physiologic><Physiological><Predisposition><Prevalence><Psychosocial Factor><Public Health><RNA Seq><RNA sequencing><RNAseq><Reporting><Research><Risk><Risk Factors><Role><Salinas Valley><Sampling><Social Environment><Statistical Methods><Susceptibility><Testing><Tissues><Transcriptional Control><Transcriptional Regulation><Variant><Variation><Writing><accelerated epigenetic age><accelerated epigenetic aging><accelerated pace of epigenetic aging><acceleration in epigenetic age><adiposity><adolescence (12-20)><age 14><age 14 years><age 18><age 18 years><age 2><age 2 years><age clock><aged 2 years><aged two years><aging biological marker><aging biomarker><aging clocks><aging induced epigenetic change><aging marker><aging-associated epigenetic change><aging-related epigenetic change><bio-markers><biologic><biologic marker><biological adaptation to stress><biomarker><cellular differentiation><child adiposity><child obesity><childhood adiposity><childhood obesity><clock measuring biological age><clock measuring biological aging><clock of biological aging><cohort><corpulence><developmental><disparities in race><disparity due to race><disparity in health><early adversity><early biomarkers><early childhood><early childhood adversity><early detection biomarkers><early detection markers><early life adversity><eighteen year old><eighteen years of age><epigenetic age clocks><epigenetic aging><epigenetic biomarker><epigenetic clock><epigenetic marker><epigenetic mechanisms in aging><epigenetic modifications in aging><epigenetic molecular clocks><epigenetic regulation of aging><epigenetically><epigenome><epigenomics><faces><facial><faster epigenetic aging><faster rates of epigenetic aging><fetal><fourteen year old><fourteen years of age><health assessment><health disparity><increased epigenetic age><increased epigenetic aging><increased rates of epigenetic aging><inequality due to race><inequity due to race><kids><long-term study><longitudinal outcome studies><longitudinal research study><machine learning based method><machine learning method><machine learning methodologies><methylation biomarker><methylation clock><methylation marker><methylation pattern><methylome><minority communities><novel><obese children><obesity during childhood><obesity in children><obesity risk><offspring><pace of aging><pace of biological aging><pathway><pediatric><pediatric obesity><post-natal period><postnatal><postnatal period><prenatal><prenatal influence><prenatal screening><prenatal testing><programs><prospective><psychosocial stresses><psychosocial stressors><psychosocial variables><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><rapid epigenetic aging><rate of aging><rate of biological aging><reactioncrisis><response><risk for obesity><risk of obesity><social><social adversity><social climate><social context><social role><socioenvironment><socioenvironmental><speed of aging><speed of the aging><statistic methods><stress response><stressreaction><stressor><transcriptome sequencing><transcriptomic sequencing><transcriptomics><two year old><two years of age><unborn><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yuwei Jiang

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$519,151

FY 2026

Project Title

Regulation of beige adipocyte maintenance and its impact on metabolic outcomes

Grant Number:

5R01DK132398-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Title: Regulation of beige adipocyte maintenance and its impact on metabolic outcomes Project Summary/Abstract A potential therapeutic target to curb the global obesity and diabetes epidemic is thermogenic beige fat within white adipose tissue (WAT). Unlike white adipocyte which stores fat, beige ad...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marcus DaSilva Goncalves

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$513,702

FY 2026

Project Title

The role of PKM2 in dietary lipid absorption and fructose-induced obesity

Grant Number:

5R01DK132427-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The increasing prevalence of obesity has been paralleled by a rise in the consumption of caloric sweeteners over the past five decades. All of the most common caloric sweeteners contain a significant proportion of fructose, including table sugar (sucrose), honey, and high-fructose corn syrup (HFCS)....

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Apoplexy><Biochemical><Brain Vascular Accident><Calories><Cardiac Diseases><Cardiac Disorders><Cell Growth in Number><Cell Locomotion><Cell Migration><Cell Movement><Cell Multiplication><Cell Proliferation><Cell Survival><Cell Viability><Cellular Migration><Cellular Motility><Cellular Proliferation><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Chylomicrons><Consumption><Cost of Illness><Data><Death><Diet><Dietary Fats><Dietary Intervention><Dietary Sucrose><Disease Costs><Drug Therapy><Eating><Energy Expenditure><Energy Metabolism><Enterocytes><Enzyme Gene><Enzymes><Exercise><Exposure to><Fats><Fatty acid glycerol esters><Feces><Food Intake><Fructose><Genetic><Genetic Models><Glucose Intolerance><Goals><Heart Diseases><High Fat Diet><Honey><Human><Hyperinsulinemia><Hyperinsulinism><Hyperplasia><Hyperplastic><Hypertrophy><Intermediary Metabolism><Intervention><Intestinal><Intestines><Isocaloric><Isoenzymes><Isoforms><Isotopes><Isozymes><Ketohexokinase><Ketosis-Resistant Diabetes Mellitus><Length><Levulose><Link><Lipid Trafficking><Lipids><Lipoproteins><Liver><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Maturity-Onset Diabetes Mellitus><Measures><Mediator><Metabolic><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modality><Modern Man><Morbid Obesity><Murine><Mus><NIDDM><Nature><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition Interventions><Nutritional Interventions><Obese Mice><Obesity><Obesity Epidemic><Organoids><Pharmacological Treatment><Pharmacotherapy><Physical activity><Play><Prevalence><Prospective Studies><Protein Isoforms><Pyruvate Kinase><Research><Risk><Role><Saccharose><Science><Severe obesity><Sickness Cost><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><Sucrose><Sweeteners><Sweetening Agents><T2 DM><T2D><T2DM><Table Sugar><Testing><Time><Tracer><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Villous><Villus><Weight Gain><Weight Increase><Western World><Wild Type Mouse><Work><absorption><adipogenesis><adiposity><adult onset diabetes><adulthood><beta-D-fructopyranose 1-phosphate><body weight gain><body weight increase><bowel><brain attack><calorie><cancer type><cell motility><cerebral vascular accident><cerebrovascular accident><clinical development><combat><corpulence><diet intervention><diet-associated obesity><diet-induced obesity><diet-related obesity><dietary><dietary lipid><dietary restriction><diets><drug intervention><drug treatment><experiment><experimental research><experimental study><experiments><extreme obesity><fat metabolism><fructose-1-phosphate><heart disorder><hepatic body system><hepatic organ system><improved><inhibitor><intestinal epithelium><ketosis resistant diabetes><lipid biosynthesis><lipid mediator><lipid metabolism><lipid transport><lipogenesis><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><nutrient absorption><ob/ob mouse><obese patients><obesigenic><obesity intervention><obesity prevention><obesity risk><obesity therapy><obesity treatment><obesogenic><patients with obesity><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><phosphoenol transphosphorylase><phosphoenolpyruvate kinase><pre-clinical><preclinical><premature><prematurity><prevent><prevent obesity><preventing><prospective research study><prospective survey><response><restricted diet><risk for obesity><risk of obesity><social role><stool><stroked><strokes><sugar><treatment strategy><type 2 DM><type II DM><type two diabetes><uptake><wildtype mouse><wt gain>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Farnaz Shamsi

NEW YORK UNIVERSITY, NEW YORK, NY

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$485,211

FY 2026

Project Title

Mechanisms of slits3 signaling in thermogenic adipose tissue

Grant Number:

5R01DK136724-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/5/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary The regulation of body temperature, thermoregulation, is a fundamental homeostatic process in warm-blooded organisms. Brown adipose tissue (BAT) plays an important role in the control of body temperature by generating heat in cold environments. BAT is functionally distinct from white...

Research Terms

<21+ years old><Address><Adipocytes><Adipose Cell><Adipose tissue><Adult><Adult Human><Affect><Anti-diabetic Agents><Anti-diabetic Drugs><BMP-1><Biological><Blood Vessels><Body Temperature><Body Temperature Regulation><Body Thermoregulation><Body Tissues><Brown Adipose Tissue><Brown Fat><C-terminal><Cardiometabolic Disease><Cardiometabolic Disorder><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chemicals><Chronic><Communication><Communities><Coupled><Data><Development><Endothelial Cells><Energy Expenditure><Energy Metabolism><Engineering><Environment><Esteroproteases><Exhibits><Fat Cells><Fat progenitor cell><Fat stem cell><Fatty Tissue><Gene Transcription><Genetic Transcription><Health><Health Care><Health Priorities><Heat Production><Hibernating Gland><House mice><Human><Intermediary Metabolism><Intracellular Communication and Signaling><Laboratories><Length><Ligands><Lipids><Lipocytes><Mature Lipocyte><Mature fat cell><Mediating><Metabolic><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Morbidity><Murine><Mus><Mus musculus><N-terminal><NH2-terminal><Nerve><Nerve Cells><Nerve Unit><Neural Cell><Neurites><Neurocyte><Neurons><Obesity><Organism><Outcome><Pathway interactions><Peptidases><Peptide Hydrolases><Physiologic Thermoregulation><Play><Preventative strategy><Prevention strategy><Preventive strategy><Process><Property><Protease Gene><Proteases><Proteinases><Proteolytic Clipping><Proteolytic Enzymes><Proteolytic Processing><RNA Expression><Reagent><Receptor Protein><Regulation><Research><Risk Factors><Rodent><Rodentia><Rodents Mammals><Role><Series><Signal Transduction><Signal Transduction Systems><Signaling><Site><Temperature><Testing><Thermogenesis><Thermoregulation><Tissues><Transcription><Type I procollagen carboxyl-terminal proteinase><Work><adipocyte progenitors><adipocyte stem cell><adipocyte-derived stem cell><adipocytokines><adipogenesis><adipokines><adipose><adipose derived stem cell><adipose progenitor><adipose stem cell><adipose tissue derived stem cell><adipose tissue stem cells><adiposity><adulthood><angiogenesis><anti-diabetic><axon growth cone guidance><axon guidance><biologic><biological signal transduction><bone morphogenetic protein 1><bone morphogenic protein 1><cardiometabolic><cardiometabolism><cell type><chemoproteomics><combat><corpulence><density><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><experiment><experimental research><experimental study><experiments><fat derived stem cell><fat metabolism><gain of function><glucose metabolism><improved><in vivo><innervation><innovate><innovation><innovative><interest><knock-down><knockdown><lipid biosynthesis><lipid metabolism><lipogenesis><living system><loss of function><mortality><mouse model><murine model><mutant><nerve supply><neuro-vascular><neuronal><neurovascular><obesigenic><obesity intervention><obesity therapy><obesity treatment><obesogenic><overexpress><overexpression><pathway><preservation><prevent><preventing><procollagen C-endopeptidase><procollagen C-protease><procollagen C-proteinase><receptor><receptor binding><receptor bound><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><transcriptomics><treatment strategy><vascular><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael A HILL

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$484,616

FY 2026

Project Title

Epithelial sodium channels in endothelial cells and arterial stiffening

Grant Number:

5R01HL172875-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Epidemiological data have established an increased incidence of cardiovascular disease events in obese individuals, with these events being strongly associated with excessive arterial stiffness. Elevated aldosterone levels and activation of vascular mineralocorticoid recept...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Guanghong Jia

UNIVERSITY OF MISSOURI-COLUMBIA, COLUMBIA, MO

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$484,616

FY 2026

Project Title

Epithelial sodium channels in endothelial cells and arterial stiffening

Grant Number:

5R01HL172875-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Epidemiological data have established an increased incidence of cardiovascular disease events in obese individuals, with these events being strongly associated with excessive arterial stiffness. Elevated aldosterone levels and activation of vascular mineralocorticoid recept...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jorge Augusto Castorena

TULANE UNIVERSITY OF LOUISIANA, NEW ORLEANS, LA

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$468,142

FY 2026

Project Title

Trpv4 regulation of lymphatic vascular function: Implications in metabolic syndrome

Grant Number:

5R01HL168568-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/20/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY A major function of the lymphatic system is fluid transport, which is critical for fluid homeostasis, lipid transport and metabolism, and the transport of immune cells and pro-inflammatory molecules. Lymphatic vessels contract spontaneously to pump fluid, while intraluminal one-way v...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARK WILLIAM DI FRANCESCO

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$451,149

FY 2026

Project Title

Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit

Grant Number:

5R01NS125316-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY There is a critical need to determine whether premature vascular disease observed in youth with type 2 diabetes (T2D) extends to the brain. This proposal builds on exciting data generated by our team showing differences in brain structure and clinically meaningful declines in neuroc...

Research Terms

<21+ years old><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><BBB permeabilization><BBB permeable><BMI><BMI percentile><BMI z-score><Blood Plasma><Blood Pressure><Blood Vessels><Body Tissues><Body Weight decreased><Body mass index><Brain><Brain Nervous System><Brain Vascular><Brain Vascular reactivity><Caring><Cerebrovascular Circulation><Cerebrovascular system><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Control Groups><Data><Development><Diabetes Mellitus><Disease><Disorder><Disturbance in cognition><Encephalon><Exercise><Eye><Eyeball><Foundations><Glia><Glial Cells><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Heart><Hemoglobin A(1)><IQ Deficit><Immediate Memory><Impaired cognition><Impairment><Intervention><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Knowledge><Kolliker's reticulum><Laboratories><Leanness><Lipids><Lupus Erythematosus Disseminatus><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Monitor><Morbidity><Morphology><NIDDM><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Neural Cell><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurocognition><Neurocognitive><Neurocognitive Deficit><Neurocyte><Neuroglia><Neuroglial Cells><Neurons><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-neuronal cell><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonneuronal cell><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><Physiologic><Physiological><Plasma><Plasma Serum><Population><Position><Positioning Attribute><Property><Quetelet index><Race><Races><Reporting><Research><Reticuloendothelial System, Serum, Plasma><Risk Factors><SLE><Short-Term Memory><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><T2 DM><T2D><T2DM><Teen><Teenagers><Testing><Thinness><Time><Tissues><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Unit of Measure><Vascular Diseases><Vascular Disorder><Weight Loss><Weight Reduction><Youth><Youth 10-21><Zeugmatography><abnormal brain function><adiposity><adult onset diabetes><adulthood><ages><arterial spin labeling><arterial spin tagging><blood flow in brain><blood vessel disorder><blood vessels in the brain><blood-brain barrier permeabilization><blood-brain barrier permeable><bloodbrain barrier permeabilization><bloodbrain barrier permeable><body weight loss><brain abnormalities><brain behavior><brain blood circulation><brain blood flow><brain blood vessels><brain dysfunction><brain health><brain impairment><brain tissue><brain vascular health><brain vasculature><brain volume><cerebral blood flow><cerebral blood vessel><cerebral circulation><cerebral vascular><cerebral vascular reactivity><cerebral vasculature><cerebro-vascular><cerebrocirculation><cerebrovascular><cerebrovascular blood flow><cerebrovascular health><cerebrovascular reactivity><cerebrovascular vessels><cerebrovasculature><cognitive dysfunction><cognitive loss><cognitive performance><cohort><corpulence><critical period><daily functioning><developmental><diabetes><disseminated lupus erythematosus><dysfunctional brain><experience><glycemic control><gray matter><hemoglobin A1c><image-based method><imaging biomarker><imaging marker><imaging method><imaging modality><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><intelligence quotient deficit><intervention design><juvenile><juvenile human><ketosis resistant diabetes><malleable risk><maturity onset diabetes><member><modifiable risk><mortality><nerve cement><neural imaging><neuro-imaging><neuro-vascular unit><neurocognitive decline><neurocognitive impairment><neuroimaging><neurological imaging><neuronal><neurovascular unit><non-diabetic><non-invasive imaging><nondiabetic><noninvasive imaging><participant retention><peer><premature><prematurity><prevent><preventing><racial><racial background><racial origin><rate of change><recruit><renal><research study><sex><substantia grisea><systemic lupus erythematosis><teen years><teenage><therapy design><treatment design><type 2 DM><type II DM><type two diabetes><vascular><vascular dysfunction><vascular risk factor><vasculopathy><working memory><wt-loss><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

AMY SANGHAVI SHAH

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$451,149

FY 2026

Project Title

Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit

Grant Number:

5R01NS125316-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY There is a critical need to determine whether premature vascular disease observed in youth with type 2 diabetes (T2D) extends to the brain. This proposal builds on exciting data generated by our team showing differences in brain structure and clinically meaningful declines in neuroc...

Research Terms

<21+ years old><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><BBB permeabilization><BBB permeable><BMI><BMI percentile><BMI z-score><Blood Plasma><Blood Pressure><Blood Vessels><Body Tissues><Body Weight decreased><Body mass index><Brain><Brain Nervous System><Brain Vascular><Brain Vascular reactivity><Caring><Cerebrovascular Circulation><Cerebrovascular system><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Control Groups><Data><Development><Diabetes Mellitus><Disease><Disorder><Disturbance in cognition><Encephalon><Exercise><Eye><Eyeball><Foundations><Glia><Glial Cells><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Heart><Hemoglobin A(1)><IQ Deficit><Immediate Memory><Impaired cognition><Impairment><Intervention><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Knowledge><Kolliker's reticulum><Laboratories><Leanness><Lipids><Lupus Erythematosus Disseminatus><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Monitor><Morbidity><Morphology><NIDDM><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Neural Cell><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurocognition><Neurocognitive><Neurocognitive Deficit><Neurocyte><Neuroglia><Neuroglial Cells><Neurons><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-neuronal cell><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonneuronal cell><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><Physiologic><Physiological><Plasma><Plasma Serum><Population><Position><Positioning Attribute><Property><Quetelet index><Race><Races><Reporting><Research><Reticuloendothelial System, Serum, Plasma><Risk Factors><SLE><Short-Term Memory><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><T2 DM><T2D><T2DM><Teen><Teenagers><Testing><Thinness><Time><Tissues><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Unit of Measure><Vascular Diseases><Vascular Disorder><Weight Loss><Weight Reduction><Youth><Youth 10-21><Zeugmatography><abnormal brain function><adiposity><adult onset diabetes><adulthood><ages><arterial spin labeling><arterial spin tagging><blood flow in brain><blood vessel disorder><blood vessels in the brain><blood-brain barrier permeabilization><blood-brain barrier permeable><bloodbrain barrier permeabilization><bloodbrain barrier permeable><body weight loss><brain abnormalities><brain behavior><brain blood circulation><brain blood flow><brain blood vessels><brain dysfunction><brain health><brain impairment><brain tissue><brain vascular health><brain vasculature><brain volume><cerebral blood flow><cerebral blood vessel><cerebral circulation><cerebral vascular><cerebral vascular reactivity><cerebral vasculature><cerebro-vascular><cerebrocirculation><cerebrovascular><cerebrovascular blood flow><cerebrovascular health><cerebrovascular reactivity><cerebrovascular vessels><cerebrovasculature><cognitive dysfunction><cognitive loss><cognitive performance><cohort><corpulence><critical period><daily functioning><developmental><diabetes><disseminated lupus erythematosus><dysfunctional brain><experience><glycemic control><gray matter><hemoglobin A1c><image-based method><imaging biomarker><imaging marker><imaging method><imaging modality><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><intelligence quotient deficit><intervention design><juvenile><juvenile human><ketosis resistant diabetes><malleable risk><maturity onset diabetes><member><modifiable risk><mortality><nerve cement><neural imaging><neuro-imaging><neuro-vascular unit><neurocognitive decline><neurocognitive impairment><neuroimaging><neurological imaging><neuronal><neurovascular unit><non-diabetic><non-invasive imaging><nondiabetic><noninvasive imaging><participant retention><peer><premature><prematurity><prevent><preventing><racial><racial background><racial origin><rate of change><recruit><renal><research study><sex><substantia grisea><systemic lupus erythematosis><teen years><teenage><therapy design><treatment design><type 2 DM><type II DM><type two diabetes><vascular><vascular dysfunction><vascular risk factor><vasculopathy><working memory><wt-loss><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Qingchun Tong

UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, HOUSTON, TX

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$447,317

FY 2026

Project Title

Neural pathways for obesity development by AgRP neurons

Grant Number:

5R01DK136284-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/19/2023

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary The development of therapeutic drugs to cure obesity has not been successful due to unwanted side effects and limited efficacy. My long-term research goal is to delineate neural pathways responsible for body weight homeostasis, and provide a framework for effective and specific thera...

Research Terms

<21+ years old><4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><ACTH-beta-Lipotropin Precursor><AGRP protein><ART protein><Ablation><Acute><Address><Adult><Adult Human><Aminalon><Aminalone><Animal Model><Animal Models and Related Studies><Area><Autoregulation><Bacteria><Bed Nucleus of Stria Terminalis><Biologic Nutritional Availability><Body Weight><Brain><Brain Nervous System><Chronic><Corticotropin-beta-Lipotropin Precursor><Cues><Development><Diet><Drugs><Dysfunction><Encephalon><Endorphin-ACTH Precursor><Energy Expenditure><Energy Metabolism><Exhibits><Feeding behaviors><Foundations><Functional disorder><GABA><Goals><Hind Brain><Homeostasis><HuB219><Hypothalamic structure><Hypothalamus><Individual><Ingestive Behavior><Investigation><Knowledge><LEP-R><LEPR Protein><Lateral Hypothalamic Area><Leptin><Leptin deficiency><Mediating><Mediator><Medication><Mesencephalic Central Gray><Mice><Mice Mammals><Midbrain Central Gray><Modeling><Murine><Mus><Neonatal><Nerve Cells><Nerve Transmitter Substances><Nerve Unit><Neural Cell><Neural Pathways><Neurocyte><Neurons><Neuropeptide Tyrosine><Neurotransmitters><Nutritional Availability><Nutritional Biological Availability><Nutritive Value><OB Receptor><OB-R><Ob Gene Product><Ob Protein><Obese Gene Product><Obese Mice><Obese Protein><Obesity><Obesity Epidemic><Pathway interactions><Periaqueductal Gray><Pharmaceutical Preparations><Physiological Homeostasis><Physiopathology><Play><Pro-ACTH-Endorphin><Pro-Opio-Melanocortin><Pro-Opiocortin><Pro-Opiomelanocortin><Proopiocortin><Proopiomelanocortin><Regulation><Research><Rhombencephalon><Rodent><Rodentia><Rodents Mammals><Role><Site><Sodium Channel><Sodium Ion Channels><Stria Terminalis Nucleus><Structure of terminal stria nuclei of preoptic region><Subgroup><Thalamic structure><Thalamus><Therapeutic><Viral><adiposity><adulthood><agouti-related protein><annulus of the aqueduct><corpulence><design><designing><developmental><diets><drug/agent><effective therapy><effective treatment><feeding><feeding-related behaviors><gamma-Aminobutyric Acid><hindbrain><hypothalamic><leptin receptor><leptin-binding protein><midbrain central gray substance><model of animal><mouse genetics><mouse model><murine model><neonate><neuronal><neuropeptide Y><neurotransmitter release><nutrient bioavailability><nutrient intake activity><ob/ob mouse><obesity development><overexpress><overexpression><parabrachial nucleus><pathophysiology><pathway><periaqueductal gray matter><pharmacologic><receptor expression><segregation><side effect><social role><thalamic><therapeutic agent development><therapeutic development><γ-Aminobutyric Acid>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Shaoning Jiang

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$443,946

FY 2026

Project Title

Macrophage miR-130b/301b and beige adipogenesis

Grant Number:

5R01DK138986-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Obesityis a global health problem that increases the risk of type 2 diabetes, cardiovascular diseases,and cancer. As the main inducible thermogenic cell type capable of improving energy homeostasis in humans, beige adipocytes are a potential therapeutic target to combat obesity and r...

Research Terms

<(hydroxymethylglutaryl-CoA reductase (NADPH)) kinase><5'-AMP-activated protein kinase><AMP-activated kinase><AMP-activated protein kinase><AMPK enzyme><Adipocytes><Adipose Cell><Adipose tissue><Adult-Onset Diabetes Mellitus><Alcoholic><Autoregulation><Back><Boozer><Cancers><Cardiovascular Diseases><Cell Body><Cell Differentiation><Cell Differentiation process><Cells><Circulation><Co-culture><Cocultivation><Coculture><Coculture Techniques><Data><Data Analyses><Data Analysis><Dependent drinker><Disease><Disorder><Dorsum><Energy Expenditure><Energy Metabolism><Fat Cells><Fat progenitor cell><Fat stem cell><Fats><Fatty Tissue><Fatty acid glycerol esters><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Functional RNA><Gene Expression><Gene Targeting><Genes><Glucose Intolerance><Goals><HMG CoA reductase (NADPH) kinase><HMG CoA reductase kinase><HMG coenzyme A reductase (NADPH) kinase><Hepatic Disorder><High Fat Diet><Homeostasis><Human><Impairment><In Vitro><Inflammation><Insulin Resistance><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out Mice><Knockout Mice><Knowledge><Lipocytes><Liver diseases><Macrophage><Macrophage Activation><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Mediating><Metabolic dysfunction><Metabolic stress><Mice><Mice Mammals><MicroRNAs><Mitochondria><Modern Man><Molecular><Murine><Mus><Myelogenous><Myeloid><Myeloid Cells><Mφ><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noncoding RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nontranslated RNA><Null Mouse><Obesity><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><Pathway interactions><Physiological Homeostasis><Production><Progenitor Cells><Publishing><RNA Seq><RNA sequencing><RNAseq><Regulation><Risk><Role><Signal Pathway><Slow-Onset Diabetes Mellitus><Source><Stable Diabetes Mellitus><Stimulus><Stromal Cells><T2 DM><T2D><T2DM><Testing><Therapeutic><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Untranslated RNA><adipocyte development><adipocyte differentiation><adipocyte progenitors><adipocyte stem cell><adipocyte-derived stem cell><adipogenesis><adipose><adipose derived stem cell><adipose progenitor><adipose stem cell><adipose tissue derived stem cell><adipose tissue stem cells><adiposity><adult onset diabetes><cardiovascular disorder><cell type><cellular differentiation><co-morbid><co-morbidity><combat><comorbidity><corpulence><data interpretation><diabetes risk><diet-associated obesity><diet-induced obesity><diet-related obesity><extracellular vesicles><fat derived stem cell><flow cytophotometry><gene network><global health><hepatic disease><hepatopathy><human model><hydroxymethylglutaryl-CoA-reductase kinase><improved><in vivo><inhibitor><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><lipid biosynthesis><lipogenesis><liver disorder><malignancy><maturity onset diabetes><miRNA><mitochondrial><mitochondrial metabolism><model of human><mouse model><murine model><neoplasm/cancer><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><noncoding><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><overexpress><overexpression><pathway><posttranscriptional><problem drinker><protective effect><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><stem><stem cells><subcutaneous><subdermal><therapeutic biomarker><therapeutic marker><therapeutic target><transcriptome sequencing><transcriptomic sequencing><transcriptomics><type 2 DM><type II DM><type two diabetes><uptake><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Julien Albert Sebag

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$442,837

FY 2026

Project Title

Investigating the requirement of MRAP2 for ghrelin function

Grant Number:

5R01DK115567-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2025

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Ghrelin is secreted by the stomach and act on hypothalamic AGRP neurons to promote food intake. Due to the potent orexigenic action of ghrelin, the ghrelin receptor GHSR1a is considered a promising target for the treatment of obesity. Our discoveries made during the first period of t...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

William Kenkel

UNIVERSITY OF DELAWARE, Newark, DE

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$337,817

FY 2026

Project Title

Avoiding Cesarean-induced Obesity Through Hormone Rescue

Grant Number:

5R01HD111737-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary / Abstract Delivery via cesarean section (CS) now makes up roughly one third of all births in the United States. After CS delivery, newborns experience lower levels of several ‘birth signaling hormones’ such as oxytocin, vasopressin, and corticosteroids. Birth is a sensitive period ...

Research Terms

<0-11 years old><0-4 weeks old><21+ years old><Abdominal Delivery><Adrenal Cortex Hormones><Adult><Adult Human><Affect><Anatomic Sites><Anatomic structures><Anatomy><Animals><Antidiuretic Hormone><Appetite><Arginine Vasopressin><Argipressin><Behavior><Birth><Body Composition><Body Temperature><Body Temperature Regulation><Body Thermoregulation><Brain><Brain Nervous System><Brain region><Budgets><C section><Cardiac Chronotropism><Cell Communication and Signaling><Cell Signaling><Cesarean><Cesarean section><Child><Child Youth><Childhood><Children (0-21)><Chronic><Complement><Complement Proteins><Corticoids><Corticosteroids><Corticosterone><Dangerousness><Desire for food><Developing fetus><Development><Eating><Encephalon><Endocrine><Endocrine Gland Secretion><Energy Expenditure><Energy Metabolism><Equilibrium><Fetal Development><Food Intake><Health><Heart Rate><Histology><Home><Hormones><Housing><Human><Hypothalamic structure><Hypothalamus><Implant><Intermediary Metabolism><Intervention><Intracellular Communication and Signaling><Life><Ligands><Locomotor Activity><Mammalia><Mammals><Measures><Metabolic><Metabolic Processes><Metabolism><Microtus><Modeling><Modern Man><Motor Activity><Nature><Neuroendocrine><Neuroendocrine System><Neuroendocrinology><Neuropeptides><Neurosecretory Systems><Newborn Infant><Newborns><Obesity><Ocytocin><Outcome><Oxytocin><Parturition><Physiologic Thermoregulation><Physiology><Play><Population><Prevalence><Public Health><Recombinant Oxytocin><Regulation><Research><Rest><Rewards><Risk><Risk Factors><Rodent><Rodent Model><Rodentia><Rodents Mammals><Role><Saccharose><Signal Transduction><Signal Transduction Systems><Signaling><Social Behavior><Sucrose><Survey Instrument><Surveys><System><Technology><Temperature><Testing><Therapeutic Hormone><Thermoregulation><United States><Vaginal delivery><Vaginal delivery procedure><Vasopressin-Neurophysin II-Copeptin><Vasopressins><Visceral><Vole><Weight Gain><Weight Increase><Work><adiposity><adulthood><balance><balance function><beta-Hypophamine><biological signal transduction><body weight gain><body weight increase><child adiposity><child obesity><childhood adiposity><childhood obesity><cold stress><complementation><corpulence><corticosterone receptor><cost effective><data streams><deliver vaginally><developmental><energy balance><experience><field mouse><food Ingestion><food consumption><homes><hormonal regulation><hormonal signals><hormone regulation><hormone signals><hypothalamic><improved><kids><later in life><later life><lens><lenses><morphometry><neural control><neural imaging><neural regulation><neuro-imaging><neuroimaging><neurological imaging><neuromodulation><neuromodulatory><neuroregulation><newborn child><newborn children><novel><obese children><obesity development><obesity during childhood><obesity in children><obesity risk><offspring><pediatric><pediatric obesity><pharmacologic><prairie vole><preference><risk for obesity><risk of obesity><social role><sociobehavior><sociobehavioral><wt gain><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Chantelle Nobile Hart

TEMPLE UNIV OF THE COMMONWEALTH, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$315,875

FY 2026

Project Title

Feasibility and Preliminary Efficacy of a Brief Behavioral Sleep Intervention for Excessive Weight Gain Prevention in Primary Care

Grant Number:

5R01DK139665-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Pediatric obesity is an epidemic with striking disparities by socioeconomic status (SES) and race/ethnicity. Thus, there is a need to identify novel approaches for obesity prevention, particularly for those at greatest risk. Primary care may be an ideal setting for obesity prevention given the high ...

Research Terms

<0-11 years old><21+ years old><6-11 years old><Accelerometer><Active Follow-up><Address><Adoption><Adult><Adult Human><African American><Afro American><Afroamerican><Approaches to prevention><Asthma><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Black><Black race><Bronchial Asthma><Caring><Cell Communication and Signaling><Cell Signaling><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Chronic><Clinical><Clinical Trials><Communities><Conditioning Therapy><Data><Disease><Disease Management><Disorder><Disorder Management><Disparities><Disparity><Eating><Eating Behavior><Education><Educational Background><Educational aspects><Effectiveness><Enrollment><Epidemic><Ethnic Origin><Ethnicity><Family><Food Intake><Goals><Health><Health Care><Health Promotion><Health care promotion><Height><Hour><Intervention><Intracellular Communication and Signaling><Life Style><Lifestyle><Maintenance><Measures><Mission><Modeling><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Obesity><Outcome><Personal Satisfaction><Phone><Physical activity><Preventative intervention><Prevention approach><Primary Care><Primary Health Care><Public Health><R.N.><RE-AIM><Race><Races><Randomized><Randomized, Controlled Trials><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Recommendation><Registered nurse><Regulation><Research Resources><Resources><Risk><Risk Factors><SES disparity><Salutogenesis><School-Age Population><Signal Transduction><Signal Transduction Systems><Signaling><Sleep><Sleep Deprivation><Socio-economic status><Socioeconomic Status><Telephone><Translations><Weight><Weight Gain><Weight Increase><Well Child Visits><Well child checks><Well child checkups><Well child exam><accelerometry><acceptability and feasibility><actigraph><actigraphy><active followup><activity monitor><activity tracker><adiposity><adulthood><allied health professional><behavior intervention><behavioral health><behavioral intervention><behavioral sleep health intervention><behavioral sleep health program><behavioral sleep intervention><behavioral sleep strategies><behavioral sleep therapy><behavioral sleep treatment><biological signal transduction><body weight gain><body weight increase><care as usual><child adiposity><child health care provider><child obesity><child routine wellness visits><child wellness visit><childhood adiposity><childhood obesity><corpulence><deficient sleep><dietary><enroll><excessive weight gain><experience><experiment><experimental research><experimental study><experiments><extreme weight gain><flexibility><flexible><follow up><follow-up><followed up><followup><healthy weight><improved><inadequate sleep><innovate><innovation><innovative><insufficient sleep><intervention delivery><intervention for prevention><kids><malleable risk><middle childhood><modifiable risk><new approaches><novel><novel approaches><novel strategies><novel strategy><obese children><obesity during childhood><obesity in children><obesity intervention><obesity prevention><obesity therapy><obesity treatment><pediatric><pediatric care provider><pediatric health care provider><pediatric obesity><pediatric preventive visit><pediatric provider><pediatric well visit><pediatrician><prevent obesity><prevention intervention><preventional intervention strategy><preventive intervention><primary care setting><profession allied to medicine><promoting health><racial><racial background><racial origin><randomisation><randomization><randomized control trial><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><response><routine child health visit><satisfaction><school age><serious weight gain><severe weight gain><sleep amount><sleep debt><sleep deficiency><sleep deficit><sleep duration><sleep episode><sleep insufficiency><sleep interval><sleep length><sleep loss><sleep period><sleep quantity><sleep time><socio-economic><socio-economic disparity><socio-economic inequality><socio-economic inequity><socio-economic position><socio-economically><socioeconomic disparity><socioeconomic inequality><socioeconomic inequity><socioeconomic position><socioeconomically><socioeconomics><staff intervention><synergism><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><translation><translational opportunities><translational potential><treatment as usual><usual care><weight gain prevention><weights><well-being><wellbeing><wt gain><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christie Befort

UNIVERSITY OF KANSAS MEDICAL CENTER, KANSAS CITY, KS

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$900,212

FY 2026

Project Title

Rural Engagement in TelemedTeam for Options in Obesity Treatment Solutions (RE-TOOL)

Grant Number:

5R01CA268034-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Obesity increases risk for 13 types of cancer and now affects over 40% of the U.S. adult population, with even higher prevalence among rural Americans. Most worrisome, the prevalence of class 3 obesity (BMI ≥ 40), which contributes the highest cancer risk, is increasing at a...

Research Terms

<21+ years old><Address><Adoption><Adult><Adult Human><Affect><Area><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Body Weight decreased><Body mass index><Caloric Intake><Cancer Cause><Cancer Etiology><Cancers><Cessation of life><Clinic><Clinic Visits><Code><Coding System><Communities><Commuting><Consumption><County><Data><Death><Dietary quality><Disparities><Disparity><Drug Therapy><Drugs><Energy Intake><Environment><Evaluation><Evidence based treatment><Exercise><Fats><Fatty acid glycerol esters><Food><Geography><Guidelines><Health><High Prevalence><High-Risk Cancer><Home><Human Resources><Improve Access><Individual><Intervention><Kansas><Knowledge><Life Style><Lifestyle><Maintenance><Malignant Neoplasms><Malignant Tumor><Manpower><Measures><Medical><Medication><Obesity><Obesity associated cancer><Obesity related cancer><Office Visits><Operative Procedures><Operative Surgical Procedures><Outcome><Participant><Patients><Pharmaceutical Preparations><Pharmacological Treatment><Pharmacotherapy><Phone><Physical activity><Plant-Based Diet><Population><Prediction of Response to Therapy><Prevalence><Primary Care><Primary Care Physician><Process><Publishing><QOL><Quality of life><Quetelet index><RE-AIM><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Recommendation><Research Resources><Resources><Risk><Rural><Rural Community><Rural Population><Rural group><Rural people><Surgical><Surgical Interventions><Surgical Procedure><Telemedicine><Telephone><Testing><Time><Tobacco><Transportation><Visit><Walking><Weight><Weight Loss><Weight Reduction><Weight maintenance regimen><adiposity><adulthood><arm><assess effectiveness><bariatric surgery><body weight loss><built environment><caloric dietary content><cancer risk><cancer type><care as usual><co-morbid><co-morbidity><comorbidity><corpulence><design><designing><determine effectiveness><diabetes prevention program><diet quality><diet rich in plants><drug intervention><drug treatment><drug/agent><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><examine effectiveness><experience><gastric banding><gastric bypass surgery><healthy lifestyle><homes><implantable gastric stimulation banding><implementation outcomes><improved><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><malignancy><neoplasm/cancer><novel><obesigenic><obesity intervention><obesity surgery><obesity therapy><obesity treatment><obesogenic><participant engagement><patient engagement><patient-clinician communication><patient-doctor communication><patient-provider communication><personnel><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><physician office visit><plant diet><plant focused diet><plant rich diet><plant-centered diet><predict therapeutic response><predict therapy response><prevent><preventing><primary care clinic><primary care provider><programs><providers from primary care><providers of primary care><reach, efficacy, adoption, implementation, and maintenance><rural Americans><rural area><rural clinic><rural dwellers><rural health clinic><rural individual><rural locality><rural location><rural place><rural region><rural resident><rural setting><secondary outcome><social culture><social disadvantage><social disparities><social inequality><socio-cultural><socio-demographic factors><sociocultural><sociodemographic factors><stomach stapling><support network><surgery><team-based care><therapy prediction><treatment as usual><treatment effect><treatment prediction><treatment response prediction><treatment trial><uptake><urban area><urban location><urban region><usual care><weight control><weight loss surgery><weight maintenance><weight management><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MOSHE LEVI

GEORGETOWN UNIVERSITY, WASHINGTON, DC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$831,580

FY 2026

Project Title

Role of Glycosphingolipids in Kidney Disease in Diabetes and Obesity

Grant Number:

5R01DK139676-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/20/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity and diabetes continue to be leading causes of chronic kidney disease (CKD). In our models of diabetes and obesity, we have found increased renal glycosphingolipids which are associated with impaired mitochondrial function, increased inflammatory T cells (Th17 cells), and progression of renal...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph A. Baur

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$776,955

FY 2026

Project Title

Targeting NAD Metabolism to Improve Glucose Homeostasis in Obesity and Aging

Grant Number:

5R01DK098656-11

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2013

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Targeting NAD Metabolism to Improve Glucose Homeostasis in Obesity and Aging We are testing the hypothesis that nicotinamide adenine dinucleotide (NAD+) metabolism can be targeted to improve physiology in aged and obese individuals. NAD+ is a ubiquitous molecule that is required as a redox cofactor ...

Research Terms

<3-Pyridinecarboxamide><3-Pyridinecarboxylic Acid><ADP Ribose Transferases><ADP-Ribosyltransferase><ADPRTs><ART Transferases><ARTases><Age><Aging><Amentia><Attention><Award><BBB penetration><Biochemical Pathway><Biochemical Reaction><Biological Markers><Biology><Blood><Blood Circulation><Blood Reticuloendothelial System><Bloodstream><Body Tissues><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cessation of life><Clinical><Clinical Research><Clinical Study><Consumption><Data><Death><Dementia><Dermatitis><Diarrhea><Dihydronicotinamide Adenine Dinucleotide><Diphosphopyridine Nucleotide><Disease><Disease Outcome><Disorder><Distal><Dose><Drug Kinetics><Electron Transport><Electrons><Enzymatic Reaction><Enzyme Gene><Enzymes><Formulation><Future><General Population><General Public><Generations><Genetic><Genetic Models><Grant><Health><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><Heterozygote><Human><Impairment><Injury><Intermediary Metabolism><Interphase Cell><Intestinal><Intestines><Intracellular Communication and Signaling><Isotope Labeling><Isotopes><Kidney><Kidney Urinary System><Knock-out><Knockout><L-Tryptophan><Learning><Levotryptophan><Literature><Liver><Liver Cells><Maps><Marketing><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measurement><Measures><Metabolic><Metabolic Networks><Metabolic Processes><Metabolism><Mice><Mice Mammals><Mitochondria><Modeling><Modern Man><Molecular><Murine><Mus><NADH><Nadide><Natural regeneration><Negative Beta Particle><Negatrons><Niacin><Niacinamide><Nicotinamide><Nicotinamide Mononucleotide><Nicotinamide adenine dinucleotide><Nicotinamide-Adenine Dinucleotide><Nicotinamidum><Nicotinic Acids><Nicotinic acid amide><Nicotylamide><Non-dividing Cell><Nondividing Cell><Nutraceutical><Obesity><Oral><Outcome><Oxidation-Reduction><Pathogenesis><Pellagra><Pellagra-Preventing Factor><Pharmacokinetics><Phenotype><Physiologic><Physiological><Physiology><Process><Publishing><Radioisotope Dilution Technic><Radioisotope Dilution Technique><Reaction><Redox><Regeneration><Resting Cell><Rodent Model><Role><Signal Transduction><Signal Transduction Systems><Signaling><Silent Mating Type Information Regulator 2-like Proteins><Sir2-like Proteins><Sirtuins><Site><Skeletal Muscle><Supplementation><Techniques><Testing><Therapeutic><Therapeutic Effect><Tissues><Tryptophan><Vitamin B 3><Vitamin B3><Vitamin PP><Voluntary Muscle><Work><adiposity><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><amidation><bio-markers><biologic marker><biological signal transduction><biomarker><blood glucose regulation><blood-brain barrier penetration><bloodbrain barrier penetration><bowel><cofactor><corpulence><deamidation><dietary><disease model><disorder model><electron energy><electron transfer><falls><glucose control><glucose homeostasis><glucose metabolism><glucose regulation><head-to-head analysis><head-to-head comparison><hepatic body system><hepatic organ system><heterozygosity><improved><in vivo><injuries><interest><isotope dilution method><mitochondrial><natural aging><nicotinamide ribonucleoside><nicotinamide ribose><nicotinamide riboside><nicotinamide-beta-riboside><normal aging><normative aging><obese individuals><obese people><obese person><obese population><obese subjects><overexpress><overexpression><oxidation><oxidation reduction reaction><population aging><pre-clinical><pre-clinical study><preclinical><preclinical study><regenerate><renal><riboside><social role><therapeutically effective><uptake><western diet><western-style diet><western-type diet>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Enrique Saez

SCRIPPS RESEARCH INSTITUTE, THE, LA JOLLA, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$766,207

FY 2026

Project Title

Pharmacologic targeting of the UPR in obesity-linked liver dysfunction

Grant Number:

5R01DK137470-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/15/2024

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY Unhealthy diets and increasingly sedentary lifestyles have led to an epidemic rise in obesity and obesity-related disorders such as Type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD), the latter of which can progress to the more severe condition nonalcoholic steatohepatitis (...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rockland Luke Wiseman

SCRIPPS RESEARCH INSTITUTE, THE, LA JOLLA, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$766,207

FY 2026

Project Title

Pharmacologic targeting of the UPR in obesity-linked liver dysfunction

Grant Number:

5R01DK137470-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/15/2024

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY Unhealthy diets and increasingly sedentary lifestyles have led to an epidemic rise in obesity and obesity-related disorders such as Type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD), the latter of which can progress to the more severe condition nonalcoholic steatohepatitis (...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nancie MacIver

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$753,296

FY 2026

Project Title

Identifying mechanisms by which metformin regulates T cell responses in obesity

Grant Number:

5R01DK139107-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/20/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity is associated with chronic inflammation and an impaired immune response to infection from select viruses, including influenza and SARS-CoV-2, leading to increased morbidity and mortality. Many studies have demonstrated a critical role for CD4+ and CD8+ T cells in this setting...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><3'5'-cyclic ester of AMP><3,5 cyclic AMP synthetase><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine Receptors><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Adenyl Cyclase><Adenylate Cyclase><Adenylyl Cyclase><Adipose tissue><Affect><Animals><Attenuated><Blood Serum><Body Tissues><Body Weight decreased><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><COVID-19><COVID-19 virus><COVID19 virus><CV-19><Caloric Restriction><Cell Body><Cell Function><Cell Isolation><Cell Physiology><Cell Process><Cell Respiration><Cell Segregation><Cell Separation><Cell Separation Technology><Cells><Cellular Function><Cellular Metabolic Process><Cellular Physiology><Cellular Process><Cellular Respiration><Chronic><CoV-2><CoV2><Communicable Diseases><Coronaviridae><Coronavirus><Coronavirus Infectious Disease 2019><Cryofixation><Cryopreservation><Cyclic AMP><Data><Diabetes Mellitus><Dimethylbiguanidine><Dimethylguanylguanidine><Disease><Disorder><Drugs><Dysfunction><Equilibrium><Eragrostis><Fatty Tissue><Functional disorder><Funding><G-Proteins><GI microbiome><GTP-Binding Proteins><GTP-Regulatory Proteins><Grippe><Guanine Nucleotide Coupling Protein><Guanine Nucleotide Regulatory Proteins><High Prevalence><History><Human><Immune><Immune response><Immunes><Impairment><In Vitro><Infection><Infectious Diseases><Infectious Disorder><Inflammation><Inflammatory><Influenza><Influenza Virus><Leanness><Link><Medication><Memory><Metabolic dysfunction><Metformin><Mice><Mice Mammals><Mitochondria><Modern Man><Molecular><Monitor><Morbidity><Murine><Mus><N,N-dimethyl-imidodicarbonimidic diamide><NIH><National Institutes of Health><Obese Mice><Obesity><Observational Study><Orthocoronavirinae><Outcome><P1 Purinoceptors><PBMC><Patients><Peripheral Blood Mononuclear Cell><Pharmaceutical Preparations><Physiopathology><Production><Purinergic P1 Receptors><Receptor Signaling><Recording of previous events><Regulatory T-Lymphocyte><Retrospective Studies><Role><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Sampling><Serum><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Severity of illness><Signal Induction><Subcellular Process><T cell response><T memory cell><T-Cell Activation><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><T8 Cells><T8 Lymphocytes><Teff><Teff cell><Testing><Thinness><Tissues><Treg><United States National Institutes of Health><Viral Diseases><Virus><Virus Diseases><Vulnerable Populations><Weight><Weight Loss><Weight Reduction><Wuhan coronavirus><activate T cells><adenosine 3'5' monophosphate><adipose><adiposity><aerobic metabolism><aerobic respiration><attenuate><attenuates><balance><balance function><bariatric surgery><biobank><biorepository><body weight loss><cAMP><calorie restriction><cell metabolism><cell sorting><cellular metabaolism><clinical relevance><clinically relevant><cold preservation><cold storage><corona virus><coronavirus disease 2019><coronavirus disease 2019 virus><coronavirus disease-19><coronavirus disease-19 virus><coronavirus infectious disease-19><corpulence><cytokine><diabetes><digestive tract microbiome><disease severity><drug discovery><drug/agent><effector T cell><enteric microbiome><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><flu infection><flu virus infection><flu virus pandemic><gastric banding><gastric bypass surgery><gastrointestinal microbiome><glucose uptake><gut microbiome><gut-associated microbiome><hCoV19><high risk group><high risk individual><high risk people><high risk population><histories><host response><human subject><immune system response><immunoresponse><implantable gastric stimulation banding><improved><infected with flu><infected with flu virus><infected with influenza><infected with influenza virus><influenza infection><influenza virus infection><influenza virus pandemic><influenzavirus><intestinal biome><intestinal microbiome><memory T lymphocyte><metabolic phenotype><metabolic profile><metabotype><mitochondrial><mortality><mouse model><murine model><nCoV2><new approaches><novel><novel approaches><novel strategies><novel strategy><ob/ob mouse><obese individuals><obese patients><obese people><obese person><obese population><obese subjects><obesity intervention><obesity surgery><obesity therapy><obesity treatment><observational research study><observational survey><oxidation><oxidative metabolism><pandemic flu><pandemic influenza><pandemic strain of influenza><pathophysiology><patients with obesity><regulatory T-cells><response><retrospective research study><retrospective survey><seasonal flu><seasonal influenza><social role><stomach stapling><systemic inflammation><systemic inflammatory response><thymus derived lymphocyte><viral infection><virus infection><virus-induced disease><vulnerable group><vulnerable individual><vulnerable people><weight loss surgery><weights><white adipose tissue><wt-loss><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph A. Baur

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$752,121

FY 2026

Project Title

Role of Activin Type II Receptor Signaling in Muscle Hypertrophy, Obesity, and Weight Loss

Grant Number:

5R01DK139663-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary GLP-1 receptor agonists and GLP-1/GIP dual agonists profoundly decrease body weight in association with significant cardiometabolic benefits. These therapeutic agents are being widely adopted for obesity treatment in the U.S. Certainly, lowering fat mass is metabolically advantageous...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Patrick Seale

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$752,121

FY 2026

Project Title

Role of Activin Type II Receptor Signaling in Muscle Hypertrophy, Obesity, and Weight Loss

Grant Number:

5R01DK139663-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary GLP-1 receptor agonists and GLP-1/GIP dual agonists profoundly decrease body weight in association with significant cardiometabolic benefits. These therapeutic agents are being widely adopted for obesity treatment in the U.S. Certainly, lowering fat mass is metabolically advantageous...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Candida Joan Rebello

LSU PENNINGTON BIOMEDICAL RESEARCH CTR, BATON ROUGE, LA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$749,481

FY 2026

Project Title

Lifestyle intervention to improve muscle function in older adults

Grant Number:

1R01AG092725-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2026

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT In the United States, nearly one third of adults over 60 years of age have sarcopenic obesity which encompasses the combined effect of muscle impairment and obesity. Inducing loss of fat mass while slowing or preventing loss of skeletal muscle mass and quality are critical f...

Research Terms

<21+ years old><Adherence><Adult><Adult Human><Aerobic Activity><Aerobic Exercise><Aerobic Training><Aerobic fitness><Aeroseb-HC><Age><Age Years><Aging><Behavioral><Biological><Body Composition><Body Weight><Body Weight decreased><Body fat><Caloric Intake><Caloric Restriction><Calorimetry><Carbohydrates><Cetacort><Conscious><Consciousness><Consumption><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Creatine><Dermacort><Diet><Diet Composition><Dietary quality><Drug Therapy><Eating><Eldecort><Endocrine Gland Secretion><Energy Intake><Equation><Equilibrium><Excretory function><Exercise><Fats><Fatty acid glycerol esters><Food><Food Intake><GLP-1><Gastric Inhibitory Polypeptide><Glp-1><Glucose-Dependent Insulin-Releasing Peptide><Glucose-Dependent Insulinotropic Peptide><Grip strength><Hand><Hand Strength><Health><Hormones><Hydrocortisone><Hydrocortone><Hytone><Impairment><Incidence><Inpatients><Insulin Resistance><Isokinetic Exercise><Isokinetics><Isometric Exercise><Isometrics><Isotonic Exercise><Isotonics><Knee><Leanness><Leptin><Macronutrients><Macronutrients Nutrition><Measures><Mental Health><Mental Hygiene><Metabolic><Methods><Modeling><Muscle><Muscle Tissue><Muscle function><Muscle-Setting Exercise><Musculoskeletal><Nutracort><Ob Gene Product><Ob Protein><Obese Gene Product><Obese Protein><Obesity><Outcome><Participant><Persons><Pharmacological Treatment><Pharmacotherapy><Physical Performance><Pilot Projects><Proctocort><Proteins><Psychological Health><Randomized><Randomized, Controlled Trials><Research><Roentgen Rays><Role><Skeletal Muscle><Static Exercise><Supervision><Testing><Therapeutic Hormone><Thinness><United States><VO2 max><VO2max><Voluntary Muscle><Walking><Weight><Weight Loss><Weight Reduction><X-Radiation><X-Ray Radiation><X-ray><Xray><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><balance><balance function><biologic><body weight loss><caloric dietary content><calorie restriction><cardiometabolic><cardiometabolism><cardiorespiratory fitness><cardiorespiratory health><cognitive benefits><corpulence><diet and exercise><diet quality><dietary><dietary composition><diets><doubly-labeled water><drug intervention><drug treatment><energy balance><energy density><excretion><exercise intervention><exercise program><feeding><fitness program><frailty><gastric inhibitory peptide><glucagon-like peptide 1><hands><high risk><improved><insight><insulin resistant><insulin sensitivity><insulin tolerance><lean body mass><life style intervention><lifestyle intervention><maximal oxygen uptake><muscle bulk><muscle form><muscle mass><muscle strength><muscular><neurocognitive disorder><older adult><older adulthood><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><physical activity intervention><physical conditioning><physical health><pilot study><population aging><preservation><prevent><preventing><randomisation><randomization><randomized control trial><randomly assigned><resistance exercise><resistance training><sarcopenic obesity><secondary analysis><skeletal muscle atrophy><skeletal muscle breakdown><skeletal muscle loss><skeletal muscle protein loss><skeletal muscle wasting><social role><trend><week trial><weight loss program><weight loss programming><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jennifer CF Leng

SLOAN-KETTERING INST CAN RESEARCH, NEW YORK, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$748,501

FY 2026

Project Title

Family COMIDA (Consumo de Opciones Más Ideales De Alimentos) (Eating More Ideal Food Options)

Grant Number:

5R01MD020111-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/29/2025

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Modified Project Summary/Abstract Section Family COMIDA (Consumo de Opciones Más Ideales De Alimentos) (Eating More Ideal Food Options) targets the obesity epidemic in the U.S., and was developed for the Hispanic population, a community at increased risk for obesity and its associated adverse health...

Research Terms

<0-11 years old><10 year old><10 years of age><21+ years old><8 year old><8 years of age><Address><Adoption><Adult><Adult Human><Application Context><Attitude><BMI><BMI percentile><BMI z-score><Behavior><Belief><Body Weight decreased><Body mass index><Care Givers><Caregivers><Chicanas><Chicanos><Child><Child Youth><Children (0-21)><Cities><Collaborations><Communities><Counseling><Data><Devices><Diet><Dietary intake><Eating><Education><Educational aspects><Effectiveness of Interventions><Espanol><Expectancy><Faith-based organization><Family><Focus Groups><Food><Food Intake><Future><Genetic><Goals><Government><Health><Health Benefit><Health Promotion><Health behavior><Health system><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Home environment><Individual><Intake><Intervention><Knowledge><Linguistic><Linguistics><Link><Literature><Low income><Maintenance><Measures><Mediation><Mediator><Methodology><Mexican><Mexican Americans><Mobile Health Units><Modeling><Monitor><Motivation><Negotiating><Negotiation><New York><New York City><Non obese><Non-Hispanic><Nonhispanic><Nonobese><Not Hispanic or Latino><Nutrition><Obesity><Obesity Epidemic><Outcome><Outcome Study><Overweight><Parents><Participant><Patient Self-Report><Phone><Physical activity><Population><Preventative intervention><Privatization><Quetelet index><Randomized><Risk><Salutogenesis><Schools><Self Efficacy><Self-Help Groups><Self-Report><Site><Spanish><Subgroup><Support Groups><Systems Theory><Telephone><Text Messaging><Time><Trust><Weight><Weight Loss><Weight Reduction><Work><Writing><Youth><Youth 10-21><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><age 10><age 10 years><age 8><age 8 years><behavior change><body weight loss><child adiposity><child obesity><childhood adiposity><childhood obesity><community setting><contextual factors><corpulence><cost><cost effective><cost estimate><cost estimation><diets><digital><disease prevention><disorder prevention><eight year old><eight years of age><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><experiment><experimental research><experimental study><experiments><health disparity community><health disparity group><health disparity populations><health related behavior><hispanic community><incremental cost-effectiveness><incrementally cost effective><innovate><innovation><innovative><intervention for prevention><kids><m-Health><mHealth><mobile health><multiphase optimization strategy><obese children><obesity during childhood><obesity in children><obesity intervention><obesity prevention><obesity risk><obesity therapy><obesity treatment><parent><pediatric obesity><prevent obesity><prevention intervention><preventional intervention strategy><preventive intervention><primary outcome><programs><promoting health><public health relevance><randomisation><randomization><randomly assigned><recruit><risk for obesity><risk of obesity><safety net><scale up><secondary outcome><self help organization><short message service><sms messaging><social><social cognitive theory><social learning theory><ten year old><ten years of age><texting><tool><uptake><waist circumference><weights><wt-loss><youngster><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mark Daniel Benson

BETH ISRAEL DEACONESS MEDICAL CENTER, BOSTON, MA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$731,254

FY 2026

Project Title

CYP4F Enzymes Regulate N-Acyl Amino Acid Signaling in Humans

Grant Number:

5R01DK137983-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity and obesity-related type 2 diabetes (T2D) pose major health threats in the US, however the early pathophysiology of these diseases remain incompletely defined. Blood-borne lipid signaling molecules called lipokines are an emerging class of endocrine factors that control syste...

Research Terms

<(hydroxymethylglutaryl-CoA reductase (NADPH)) kinase><5'-AMP-activated protein kinase><AMP-activated kinase><AMP-activated protein kinase><AMPK enzyme><Acids><Address><Adult-Onset Diabetes Mellitus><Amino Acids><Animal Model><Animal Models and Related Studies><Anti-diabetic Agents><Anti-diabetic Drugs><Arachidonic Acids><Autoregulation><Biochemical><Biologic Models><Biological><Biological Markers><Biological Models><Blood><Blood Plasma><Blood Reticuloendothelial System><Body Tissues><Body Weight><CYP4F11><CYP4F11 gene><Cardiometabolic Disease><Cardiometabolic Disorder><Catabolism><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell model><Cells><Cellular model><Coronary Disease><Coronary heart disease><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 Family Gene><Cytochrome P450, Family 4, Subfamily F, Polypeptide 11><Cytochrome P450, Subfamily IVF, Polypeptide 11><D-Glucose><Data><Dextrose><Diabetes Mellitus><Disease><Disorder><Dysfunction><Eicosanoids><Endocrine><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Family><Family member><Fatty Acid Metabolism Pathway><Fatty Acids><Functional disorder><Future><GWA study><GWAS><Genetic Determinism><Genomics><Glucose><Goals><HMG CoA reductase (NADPH) kinase><HMG CoA reductase kinase><HMG coenzyme A reductase (NADPH) kinase><Health><Heart failure><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><Homeostasis><Human><Human Biology><Hydroxylases><Hydroxylation><In Vitro><Individual><Insulin homeostasis><Intermediary Metabolism><Intracellular Communication and Signaling><Investigation><Isotope Labeling><Jackson Heart Study><Ketosis-Resistant Diabetes Mellitus><Laboratories><Leucine><Lipids><Liver Cells><Maps><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Maturity-Onset Diabetes Mellitus><Measures><Mendelian randomization><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Methods><Mice><Mice Mammals><Mitochondria><Mixed Function Oxidases><Mixed Function Oxygenases><Model System><Modeling><Modern Man><Monooxygenases><Multi-Ethnic Study of Atherosclerosis><Murine><Mus><N hydroxylation><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><P450><Participant><Pathway interactions><Phenotype><Phenylalanine><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Plasma><Plasma Serum><Play><Prevention><Property><Proteins><Reaction><Recombinants><Respiration><Reticuloendothelial System, Serum, Plasma><Risk><Rodent><Rodentia><Rodents Mammals><Role><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><System><T2 DM><T2D><T2DM><Testing><Therapeutic><Thesaurismosis><Tissues><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><adiposity><adult onset diabetes><aminoacid><anti-diabetic><arachidonic metabolism><bio-markers><biologic><biologic marker><biological signal transduction><biomarker><blood glucose regulation><cardiac failure><cardiometabolic><cardiometabolism><cell type><coronary disorder><corpulence><diabetes><disease model><disorder model><eicosanoid metabolism><fatty acid metabolism><gene locus><genetic determinant><genetic locus><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><human population study><hydroxy fatty acid><hydroxymethylglutaryl-CoA-reductase kinase><improved><inhibitor><insight><insulin balance><insulin control><ketosis resistant diabetes><lipophilicity><maturity onset diabetes><metabolism disorder><metabolism measurement><metabolomics><metabonomics><mitochondrial><model of animal><mouse model><murine model><novel><obesity intervention><obesity prevention><obesity therapy><obesity treatment><oxidation><pathophysiology><pathway><peroxisome><pharmacologic><prevent obesity><respiratory mechanism><social role><therapeutic target><treatment strategy><type 2 DM><type II DM><type two diabetes><whole genome association analysis><whole genome association study>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Meera Goh Nair

UNIVERSITY OF CALIFORNIA RIVERSIDE, RIVERSIDE, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$728,966

FY 2026

Project Title

Sex-dependent innate immune mechanisms in type 2 immunity and obesity

Grant Number:

5R01AI191470-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/2/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity is a rising public health concern linked to multiple preventable comorbidities, such as worse infection outcomes, inflammatory disorders, and type 2 diabetes. Obesity affects the immune system, and the underlying immune response is a critical regulator of its outcome. A more common type 1 (T...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LAURIE J GOODYEAR

JOSLIN DIABETES CENTER, BOSTON, MA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$716,991

FY 2026

Project Title

Novel Mechanisms of Exercise Training Effects on Glucose Homeostasis

Grant Number:

5R01DK099511-12

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2014

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it has long been established that exercise training can have profound effects on systemic glucose homeostasis and skeletal muscle metabolism, more recent research has demonstrated that adipose tissues also play an important role in mediating the benefits of exercise on...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rachel A Ross

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$702,078

FY 2026

Project Title

Top Down Regulation of Feeding-related Behavior

Grant Number:

5R01DK141837-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/20/2024

End Date:

11/20/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity is one of the greatest public health concerns facing our country. The condition is linked to deficits in specific domains of cognitive function, namely working memory and behavior inhibition, which can affect food seeking and food intake behavior. Melanocortin peptides in th...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mandar Deepak Muzumdar

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$692,948

FY 2026

Project Title

Targeting pancreatic endocrine-exocrine signaling in cancer development with incretin mimetics

Grant Number:

5R01CA296916-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Incretin mimetics, such as glucagon-like peptide-1 receptor agonists (GLP-1RAs), have revolutionized obesity and diabetes treatment, become first-line anti-obesity medications, and may soon be more widely used for other indications including cardiovascular and renal disease ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Justin R. Ryder

LURIE CHILDREN'S HOSPITAL OF CHICAGO, CHICAGO, IL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$691,697

FY 2026

Project Title

Adaptive Mechanisms Responsible for Weight Regain in Youth with Obesity and the Influence of Sex

Grant Number:

5R01DK127991-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary / Abstract Pediatric obesity is a pervasive problem in the United States. While short-term weight loss can be achieved in a high proportion of adolescents with obesity the ability to prevent subsequent weight and fat mass regain long-term is extremely challenging. The mechanisms und...

Research Terms

<0-11 years old><12-20 years old><15 year old><15 years of age><19 year old><19 years of age><21+ years old><Address><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Appetite><Automobile Driving><Autoregulation><BMI><BMI percentile><BMI z-score><Behavioral><Biological><Biology><Body Weight decreased><Body mass index><Characteristics><Child><Child Youth><Children (0-21)><DEXA><DXA><Desire for food><Development><Dietary intake><Differences between sexes><Differs between sexes><Disease remission><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Eating Behavior><Endocrine Gland Secretion><Energy Expenditure><Energy Metabolism><Fats><Fatty acid glycerol esters><Female><Female Adolescents><Gastric Inhibitory Polypeptide><Generalized Growth><Glucose-Dependent Insulin-Releasing Peptide><Glucose-Dependent Insulinotropic Peptide><Gonadal Steroid Hormones><Growth><Health behavior><Homeostasis><Hormonal><Hormonal Change><Hormones><Human Development><Indirect Calorimetry><Individual><Insulinoma amyloid peptide><Intervention><Intervention Strategies><L-tyrosyl-L-tyrosine><Leptin><Life Style Modification><Maintenance><Measures><Mediating><Metabolic><Neuroendocrine><Neuroendocrine System><Neurosecretory Systems><Ob Gene Product><Ob Protein><Obese Gene Product><Obese Protein><Obesity><PYY Peptide><Pediatrics><Peptide YY><Phase><Physical activity><Physiological Homeostasis><Play><Population><Prevention><Process><Protocol><Protocols documentation><Puberty><Questionnaires><Quetelet index><Regulation><Remission><Replacement Therapy><Respiration Calorimetry><Rest><Role><Satiation><Sex Differences><Sex Hormones><Sex Steroid Hormones><Sexual differences><Testing><Therapeutic Hormone><Tissue Growth><Total Daily Energy Expenditure><Tyr-Tyr><United States><Weight><Weight Loss><Weight Reduction><Work><Youth><Youth 10-21><actigraph><actigraphy><adiposity><adolescence (12-20)><adolescent girl><adulthood><age 15><age 15 years><age 19><age 19 years><amlintide><amylin><behavior phenotype><behavioral phenotyping><biologic><body weight loss><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical care><corpulence><customized therapy><customized treatment><developmental><diabetes associated peptide><doubly-labeled water><driving><driving behavior><energy balance><energy efficiency><experience><fifteen year old><fifteen years of age><gastric inhibitory peptide><ghrelin><gonadal steroids><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><health related behavior><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><insulinoma amyloid polypeptide><islet amyloid polypeptide><juvenile><juvenile human><kids><life span><lifespan><lifestyle modification><male><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><nineteen year old><nineteen years old><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><obese children><obesity during childhood><obesity in children><ontogeny><pancreatic amylin><patient specific therapies><patient specific treatment><pediatric obesity><peptide tyrosine-tyrosine><premature><prematurity><preservation><prevent><preventing><primary outcome><psychosocial><public health relevance><reproductive><response><satiety><sex><sex based differences><sex steroid><sex-dependent differences><sex-related differences><sex-specific differences><social role><success><tailored medical treatment><tailored therapy><tailored treatment><total energy expenditure><tyrosyltyrosine><unique treatment><weight maintenance><weights><wt-loss><youngster><youth age><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LIANGYOU RUI

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$684,895

FY 2026

Project Title

Role of hypothalamic SH2B1 neurocircuits and SH2B1 signal transduction pathways in obesity and metabolic disease

Grant Number:

5R01DK141559-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract (Description) SH2B1 is an adaptor protein that mediates signal transduction in response to a range of ligands, including brain-derived neurotrophic factor (BDNF). SH2B1 defends against energy imbalance and obesity in both humans and mice. We reported that systemic deletion of Sh2b1 results ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alexandra Gold DiFeliceantonio

VIRGINIA POLYTECHNIC INST AND ST UNIV, BLACKSBURG, VA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$683,750

FY 2026

Project Title

Sub-second catecholamine dynamics underlying food reward in humans

Grant Number:

5R01DK141764-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2025

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY The prevalence of obesity in the United States (US) has been consistently rising. For individuals with obesity the lifetime risk of developing type 2 diabetes (T2D) is 3-7 times greater than for those without. Despite substantial advances in obesity treatment, obesity and T2D remain global p...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

William Matthew Howe

VIRGINIA POLYTECHNIC INST AND ST UNIV, BLACKSBURG, VA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$683,750

FY 2026

Project Title

Sub-second catecholamine dynamics underlying food reward in humans

Grant Number:

5R01DK141764-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2025

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY The prevalence of obesity in the United States (US) has been consistently rising. For individuals with obesity the lifetime risk of developing type 2 diabetes (T2D) is 3-7 times greater than for those without. Despite substantial advances in obesity treatment, obesity and T2D remain global p...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

P Read Montague

VIRGINIA POLYTECHNIC INST AND ST UNIV, BLACKSBURG, VA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$683,750

FY 2026

Project Title

Sub-second catecholamine dynamics underlying food reward in humans

Grant Number:

5R01DK141764-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2025

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY The prevalence of obesity in the United States (US) has been consistently rising. For individuals with obesity the lifetime risk of developing type 2 diabetes (T2D) is 3-7 times greater than for those without. Despite substantial advances in obesity treatment, obesity and T2D remain global p...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Paulette B. Goforth

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$674,229

FY 2026

Project Title

Defining roles for area postrema neuron cell types in food intake and nausea

Grant Number:

5R01DK132008-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2023

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Obesity contributes to the development of type 2 diabetes and other chronic diseases, while weight loss ameliorates the risk for these maladies. Current medical therapies remain inadequate to combatting the ongoing US obesity epidemic, however- in part because some of the most promising obe...

Research Terms

<4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><Adult-Onset Diabetes Mellitus><Affect><Agonist><Aminalon><Aminalone><Anorectic Drug><Anorectic agent><Anorectics><Anorexia><Anorexiant><Anorexic Drugs><Anorexient Agent><Anorexient Drug><Anorexigenic Drugs><Appetite><Appetite Depressants><Appetite Suppressants><Appetite-Depressing Drugs><Appetite-Suppressant Drugs><Area Postrema><Assay><Aversive Stimulus><Behavioral><Behavioral Assay><Bioassay><Biological Assay><Blood - brain barrier anatomy><Blood-Brain Barrier><Body Weight decreased><Brain><Brain Nervous System><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic Disease><Chronic Illness><Common Rat Strains><Complex><DREADDs><Data><Desire for food><Development><Dorsal><Drugs><Eating><Electrophysiology><Electrophysiology (science)><Encephalon><Food Intake><GABA><GDF15><GDF15 gene><GIPR><GIPR gene><Gene Modified><Genetic><Glutamates><Hemato-Encephalic Barrier><Human><IAPP receptor><Image><Individual><Injections><Insulinoma amyloid peptide><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><L-Glutamate><MIC-1 gene product><MIC1><Macrophage Inhibitory Cytokine-1><Mammalian Genetics><Maturity-Onset Diabetes Mellitus><Mediating><Medical><Medication><Methods><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><NAG-1 protein><NAG1><NIDDM><NSAID activated gene-1 product><NSAID-Activated Protein 1><NSAID-Regulated Protein 1><Nausea><Nausea and Vomiting><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurophysiology / Electrophysiology><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonsteroidal Anti-Inflammatory Drug-Activated Protein 1><Nutrient><Obesity><Obesity Epidemic><PLAB><PLAB Protein><PTGF-Beta><Pathologic><Pattern><Pharmaceutical Preparations><Physiologic><Physiological><Placental Bone Morphogenic Protein><Placental TGF-Beta><Population><Prostate Differentiation Factor><RAMP3><Rat><Rats Mammals><Rattus><Receptor Protein><Regulation><Reporter><Risk><Role><Satiation><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure of area postrema><System><T2 DM><T2D><T2DM><Therapeutic><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight Loss><Weight Reduction><adiposity><adult onset diabetes><amlintide><amylin><amylin receptor><anorexic agent><biological signal transduction><bloodbrain barrier><body weight loss><cell type><chronic disorder><combat><corpulence><design><designer receptors exclusively activated by designer drugs><designing><detection of nutrient><developmental><diabetes associated peptide><drug/agent><electrophysiological><feeding><gamma-Aminobutyric Acid><gene modification><genetically modified><glutamatergic><growth differentiation factor 15><imaging><improved><insulinoma amyloid polypeptide><islet amyloid polypeptide><islet amyloid polypeptide receptor><ketosis resistant diabetes><maturity onset diabetes><neural><neuronal><novel><nutrient sensing><obesity intervention><obesity therapy><obesity treatment><pancreatic amylin><parabrachial nucleus><perception of nutrients><pharmacologic><rational design><receptor><response><satiety><single cell analysis><social role><type 2 DM><type II DM><type two diabetes><weight loss intervention><weight loss therapy><weight loss treatment><wt-loss><γ-Aminobutyric Acid>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Martin G Myers

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$674,229

FY 2026

Project Title

Defining roles for area postrema neuron cell types in food intake and nausea

Grant Number:

5R01DK132008-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2023

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Obesity contributes to the development of type 2 diabetes and other chronic diseases, while weight loss ameliorates the risk for these maladies. Current medical therapies remain inadequate to combatting the ongoing US obesity epidemic, however- in part because some of the most promising obe...

Research Terms

<4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><Adult-Onset Diabetes Mellitus><Affect><Agonist><Aminalon><Aminalone><Anorectic Drug><Anorectic agent><Anorectics><Anorexia><Anorexiant><Anorexic Drugs><Anorexient Agent><Anorexient Drug><Anorexigenic Drugs><Appetite><Appetite Depressants><Appetite Suppressants><Appetite-Depressing Drugs><Appetite-Suppressant Drugs><Area Postrema><Assay><Aversive Stimulus><Behavioral><Behavioral Assay><Bioassay><Biological Assay><Blood - brain barrier anatomy><Blood-Brain Barrier><Body Weight decreased><Brain><Brain Nervous System><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic Disease><Chronic Illness><Common Rat Strains><Complex><DREADDs><Data><Desire for food><Development><Dorsal><Drugs><Eating><Electrophysiology><Electrophysiology (science)><Encephalon><Food Intake><GABA><GDF15><GDF15 gene><GIPR><GIPR gene><Gene Modified><Genetic><Glutamates><Hemato-Encephalic Barrier><Human><IAPP receptor><Image><Individual><Injections><Insulinoma amyloid peptide><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><L-Glutamate><MIC-1 gene product><MIC1><Macrophage Inhibitory Cytokine-1><Mammalian Genetics><Maturity-Onset Diabetes Mellitus><Mediating><Medical><Medication><Methods><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><NAG-1 protein><NAG1><NIDDM><NSAID activated gene-1 product><NSAID-Activated Protein 1><NSAID-Regulated Protein 1><Nausea><Nausea and Vomiting><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurophysiology / Electrophysiology><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonsteroidal Anti-Inflammatory Drug-Activated Protein 1><Nutrient><Obesity><Obesity Epidemic><PLAB><PLAB Protein><PTGF-Beta><Pathologic><Pattern><Pharmaceutical Preparations><Physiologic><Physiological><Placental Bone Morphogenic Protein><Placental TGF-Beta><Population><Prostate Differentiation Factor><RAMP3><Rat><Rats Mammals><Rattus><Receptor Protein><Regulation><Reporter><Risk><Role><Satiation><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure of area postrema><System><T2 DM><T2D><T2DM><Therapeutic><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight Loss><Weight Reduction><adiposity><adult onset diabetes><amlintide><amylin><amylin receptor><anorexic agent><biological signal transduction><bloodbrain barrier><body weight loss><cell type><chronic disorder><combat><corpulence><design><designer receptors exclusively activated by designer drugs><designing><detection of nutrient><developmental><diabetes associated peptide><drug/agent><electrophysiological><feeding><gamma-Aminobutyric Acid><gene modification><genetically modified><glutamatergic><growth differentiation factor 15><imaging><improved><insulinoma amyloid polypeptide><islet amyloid polypeptide><islet amyloid polypeptide receptor><ketosis resistant diabetes><maturity onset diabetes><neural><neuronal><novel><nutrient sensing><obesity intervention><obesity therapy><obesity treatment><pancreatic amylin><parabrachial nucleus><perception of nutrients><pharmacologic><rational design><receptor><response><satiety><single cell analysis><social role><type 2 DM><type II DM><type two diabetes><weight loss intervention><weight loss therapy><weight loss treatment><wt-loss><γ-Aminobutyric Acid>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RANDY J SEELEY

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$674,229

FY 2026

Project Title

Defining roles for area postrema neuron cell types in food intake and nausea

Grant Number:

5R01DK132008-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2023

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Obesity contributes to the development of type 2 diabetes and other chronic diseases, while weight loss ameliorates the risk for these maladies. Current medical therapies remain inadequate to combatting the ongoing US obesity epidemic, however- in part because some of the most promising obe...

Research Terms

<4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><Adult-Onset Diabetes Mellitus><Affect><Agonist><Aminalon><Aminalone><Anorectic Drug><Anorectic agent><Anorectics><Anorexia><Anorexiant><Anorexic Drugs><Anorexient Agent><Anorexient Drug><Anorexigenic Drugs><Appetite><Appetite Depressants><Appetite Suppressants><Appetite-Depressing Drugs><Appetite-Suppressant Drugs><Area Postrema><Assay><Aversive Stimulus><Behavioral><Behavioral Assay><Bioassay><Biological Assay><Blood - brain barrier anatomy><Blood-Brain Barrier><Body Weight decreased><Brain><Brain Nervous System><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic Disease><Chronic Illness><Common Rat Strains><Complex><DREADDs><Data><Desire for food><Development><Dorsal><Drugs><Eating><Electrophysiology><Electrophysiology (science)><Encephalon><Food Intake><GABA><GDF15><GDF15 gene><GIPR><GIPR gene><Gene Modified><Genetic><Glutamates><Hemato-Encephalic Barrier><Human><IAPP receptor><Image><Individual><Injections><Insulinoma amyloid peptide><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><L-Glutamate><MIC-1 gene product><MIC1><Macrophage Inhibitory Cytokine-1><Mammalian Genetics><Maturity-Onset Diabetes Mellitus><Mediating><Medical><Medication><Methods><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><NAG-1 protein><NAG1><NIDDM><NSAID activated gene-1 product><NSAID-Activated Protein 1><NSAID-Regulated Protein 1><Nausea><Nausea and Vomiting><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurophysiology / Electrophysiology><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonsteroidal Anti-Inflammatory Drug-Activated Protein 1><Nutrient><Obesity><Obesity Epidemic><PLAB><PLAB Protein><PTGF-Beta><Pathologic><Pattern><Pharmaceutical Preparations><Physiologic><Physiological><Placental Bone Morphogenic Protein><Placental TGF-Beta><Population><Prostate Differentiation Factor><RAMP3><Rat><Rats Mammals><Rattus><Receptor Protein><Regulation><Reporter><Risk><Role><Satiation><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure of area postrema><System><T2 DM><T2D><T2DM><Therapeutic><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight Loss><Weight Reduction><adiposity><adult onset diabetes><amlintide><amylin><amylin receptor><anorexic agent><biological signal transduction><bloodbrain barrier><body weight loss><cell type><chronic disorder><combat><corpulence><design><designer receptors exclusively activated by designer drugs><designing><detection of nutrient><developmental><diabetes associated peptide><drug/agent><electrophysiological><feeding><gamma-Aminobutyric Acid><gene modification><genetically modified><glutamatergic><growth differentiation factor 15><imaging><improved><insulinoma amyloid polypeptide><islet amyloid polypeptide><islet amyloid polypeptide receptor><ketosis resistant diabetes><maturity onset diabetes><neural><neuronal><novel><nutrient sensing><obesity intervention><obesity therapy><obesity treatment><pancreatic amylin><parabrachial nucleus><perception of nutrients><pharmacologic><rational design><receptor><response><satiety><single cell analysis><social role><type 2 DM><type II DM><type two diabetes><weight loss intervention><weight loss therapy><weight loss treatment><wt-loss><γ-Aminobutyric Acid>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Monique Marie Hedderson

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$671,519

FY 2026

Project Title

Comparing the effects of pharmacological treatment for gestational diabetes on long-term maternal and child health outcomes

Grant Number:

5R01DK138135-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/20/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Gestational diabetes mellitus (GDM) is among the most common complications of pregnancy and it increases the risk of perinatal complications and long-term sequelae for both the mother (subsequent diabetes) and the exposed child (obesity). Up to 50% of women with GDM require the addition of ...

Research Terms

<0-11 years old><10 year old><10 years of age><ACOG><Active Follow-up><Affect><American><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><Beta Cell><California><Cardiovascular Diseases><Cells Placenta-Tissue><Child><Child Youth><Children (0-21)><Clinical><Clinical Data><Cohort Studies><Data><Demography><Diabetes Mellitus><Diagnosis><Diet therapy><Dimethylbiguanidine><Dimethylguanylguanidine><Dose><Drug Kinetics><Drug Therapy><Drugs><Electronic Health Record><Exclusion Criteria><Exposure to><Fetal Tissues><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glibenclamide><Glybenclamide><Glyburide><Growth><Guidelines><Health><Humulin R><Hypertension><Hypoglycemic Agents><Hypoglycemic Drugs><Hypoglycemics><Incidence><Infant><Insulin><Insulin Cell><Insulin Secreting Cell><Intention><Knowledge><Long-Term Effects><Long-term Follow-up><Long-term cohort study><Longitudinal cohort study><Machine Learning><Maternal and Child Health><Medical><Medication><Metabolic><Metformin><Methodology><Methods><Micronase><Modernization><Mothers><N,N-dimethyl-imidodicarbonimidic diamide><Neonatal Hypoglycemia><Normal Placentoma><Novolin R><Nutritional Support><Obesity><Observational Study><Oral><Outcome><Patients><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Placenta><Placenta Embryonic Tissue><Placentome><Population><Population Heterogeneity><Population Research><Population-based research><Population-level research><Postpartum Period><Pregnancy><Pregnancy Complications><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Preventative strategy><Prevention strategy><Preventive strategy><Property><Protocol><Protocols documentation><Randomized, Controlled Trials><Recommendation><Regimen><Regular Insulin><Risk><Risk Factors><Risk Reduction><Safety><Sample Size><Selection Bias><Series><Severities><Site><Specific qualifier value><Specified><Statistical Methods><Time><Tissue Growth><Treatment Protocols><Treatment Regimen><Treatment Schedule><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><active comparator><active comparison control><active followup><adiposity><after pregnancy><age 10><age 10 years><antihyperglycemic><cardiometabolic><cardiometabolism><cardiovascular disorder><care as usual><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical practice><cohort research study><cohort survey><complications during pregnancy><corpulence><cost><data collected in real world><diabetes><diabetes risk><diagnosis among females><diagnosis among women><diagnosis in females><diagnosis in women><diagnosis within females><diagnosis within women><dietary therapy><diverse populations><drug intervention><drug treatment><drug/agent><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><exhaustion><expectant mother><expectant women><expecting mother><expecting women><female diagnosis><fetus tissue><follow up><follow-up><followed up><followup><glycemic control><head-to-head analysis><head-to-head comparison><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><individuals who are pregnant><infantile hypoglycemia><investigate population><kids><long-term followup><long-term sequelae><machine based learning><maternal diabetes><maternal risk><member><nutritional care><nutritional therapy><obese children><obesity during childhood><obesity in children><obesity risk><observational research study><observational survey><ontogeny><optimal therapies><optimal treatments><overweight child><overweight childhood><pediatric obesity><people who are pregnant><perinatal complications><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><population diversity><population investigation><population level investigation><population specific research><post pregnancy><post-partum><pragmatic randomized trial><pregnancy diabetes><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prepregnancy obesity><preterm delivery><randomized control trial><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk for obesity><risk of obesity><risk-reducing><statistic methods><studies of populations><study of the population><study population><survey population><ten year old><ten years of age><those who are pregnant><treatment as usual><treatment strategy><trial comparing><usual care><women who are pregnant><women's diagnosis><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Romain Neugebauer

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$671,519

FY 2026

Project Title

Comparing the effects of pharmacological treatment for gestational diabetes on long-term maternal and child health outcomes

Grant Number:

5R01DK138135-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/20/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Gestational diabetes mellitus (GDM) is among the most common complications of pregnancy and it increases the risk of perinatal complications and long-term sequelae for both the mother (subsequent diabetes) and the exposed child (obesity). Up to 50% of women with GDM require the addition of ...

Research Terms

<0-11 years old><10 year old><10 years of age><ACOG><Active Follow-up><Affect><American><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><Beta Cell><California><Cardiovascular Diseases><Cells Placenta-Tissue><Child><Child Youth><Children (0-21)><Clinical><Clinical Data><Cohort Studies><Data><Demography><Diabetes Mellitus><Diagnosis><Diet therapy><Dimethylbiguanidine><Dimethylguanylguanidine><Dose><Drug Kinetics><Drug Therapy><Drugs><Electronic Health Record><Exclusion Criteria><Exposure to><Fetal Tissues><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glibenclamide><Glybenclamide><Glyburide><Growth><Guidelines><Health><Humulin R><Hypertension><Hypoglycemic Agents><Hypoglycemic Drugs><Hypoglycemics><Incidence><Infant><Insulin><Insulin Cell><Insulin Secreting Cell><Intention><Knowledge><Long-Term Effects><Long-term Follow-up><Long-term cohort study><Longitudinal cohort study><Machine Learning><Maternal and Child Health><Medical><Medication><Metabolic><Metformin><Methodology><Methods><Micronase><Modernization><Mothers><N,N-dimethyl-imidodicarbonimidic diamide><Neonatal Hypoglycemia><Normal Placentoma><Novolin R><Nutritional Support><Obesity><Observational Study><Oral><Outcome><Patients><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Placenta><Placenta Embryonic Tissue><Placentome><Population><Population Heterogeneity><Population Research><Population-based research><Population-level research><Postpartum Period><Pregnancy><Pregnancy Complications><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Preventative strategy><Prevention strategy><Preventive strategy><Property><Protocol><Protocols documentation><Randomized, Controlled Trials><Recommendation><Regimen><Regular Insulin><Risk><Risk Factors><Risk Reduction><Safety><Sample Size><Selection Bias><Series><Severities><Site><Specific qualifier value><Specified><Statistical Methods><Time><Tissue Growth><Treatment Protocols><Treatment Regimen><Treatment Schedule><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><active comparator><active comparison control><active followup><adiposity><after pregnancy><age 10><age 10 years><antihyperglycemic><cardiometabolic><cardiometabolism><cardiovascular disorder><care as usual><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical practice><cohort research study><cohort survey><complications during pregnancy><corpulence><cost><data collected in real world><diabetes><diabetes risk><diagnosis among females><diagnosis among women><diagnosis in females><diagnosis in women><diagnosis within females><diagnosis within women><dietary therapy><diverse populations><drug intervention><drug treatment><drug/agent><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><exhaustion><expectant mother><expectant women><expecting mother><expecting women><female diagnosis><fetus tissue><follow up><follow-up><followed up><followup><glycemic control><head-to-head analysis><head-to-head comparison><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><individuals who are pregnant><infantile hypoglycemia><investigate population><kids><long-term followup><long-term sequelae><machine based learning><maternal diabetes><maternal risk><member><nutritional care><nutritional therapy><obese children><obesity during childhood><obesity in children><obesity risk><observational research study><observational survey><ontogeny><optimal therapies><optimal treatments><overweight child><overweight childhood><pediatric obesity><people who are pregnant><perinatal complications><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><population diversity><population investigation><population level investigation><population specific research><post pregnancy><post-partum><pragmatic randomized trial><pregnancy diabetes><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prepregnancy obesity><preterm delivery><randomized control trial><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk for obesity><risk of obesity><risk-reducing><statistic methods><studies of populations><study of the population><study population><survey population><ten year old><ten years of age><those who are pregnant><treatment as usual><treatment strategy><trial comparing><usual care><women who are pregnant><women's diagnosis><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ANNY H XIANG

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$671,519

FY 2026

Project Title

Comparing the effects of pharmacological treatment for gestational diabetes on long-term maternal and child health outcomes

Grant Number:

5R01DK138135-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/20/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Gestational diabetes mellitus (GDM) is among the most common complications of pregnancy and it increases the risk of perinatal complications and long-term sequelae for both the mother (subsequent diabetes) and the exposed child (obesity). Up to 50% of women with GDM require the addition of ...

Research Terms

<0-11 years old><10 year old><10 years of age><ACOG><Active Follow-up><Affect><American><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><Beta Cell><California><Cardiovascular Diseases><Cells Placenta-Tissue><Child><Child Youth><Children (0-21)><Clinical><Clinical Data><Cohort Studies><Data><Demography><Diabetes Mellitus><Diagnosis><Diet therapy><Dimethylbiguanidine><Dimethylguanylguanidine><Dose><Drug Kinetics><Drug Therapy><Drugs><Electronic Health Record><Exclusion Criteria><Exposure to><Fetal Tissues><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glibenclamide><Glybenclamide><Glyburide><Growth><Guidelines><Health><Humulin R><Hypertension><Hypoglycemic Agents><Hypoglycemic Drugs><Hypoglycemics><Incidence><Infant><Insulin><Insulin Cell><Insulin Secreting Cell><Intention><Knowledge><Long-Term Effects><Long-term Follow-up><Long-term cohort study><Longitudinal cohort study><Machine Learning><Maternal and Child Health><Medical><Medication><Metabolic><Metformin><Methodology><Methods><Micronase><Modernization><Mothers><N,N-dimethyl-imidodicarbonimidic diamide><Neonatal Hypoglycemia><Normal Placentoma><Novolin R><Nutritional Support><Obesity><Observational Study><Oral><Outcome><Patients><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Placenta><Placenta Embryonic Tissue><Placentome><Population><Population Heterogeneity><Population Research><Population-based research><Population-level research><Postpartum Period><Pregnancy><Pregnancy Complications><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Preventative strategy><Prevention strategy><Preventive strategy><Property><Protocol><Protocols documentation><Randomized, Controlled Trials><Recommendation><Regimen><Regular Insulin><Risk><Risk Factors><Risk Reduction><Safety><Sample Size><Selection Bias><Series><Severities><Site><Specific qualifier value><Specified><Statistical Methods><Time><Tissue Growth><Treatment Protocols><Treatment Regimen><Treatment Schedule><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><active comparator><active comparison control><active followup><adiposity><after pregnancy><age 10><age 10 years><antihyperglycemic><cardiometabolic><cardiometabolism><cardiovascular disorder><care as usual><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical practice><cohort research study><cohort survey><complications during pregnancy><corpulence><cost><data collected in real world><diabetes><diabetes risk><diagnosis among females><diagnosis among women><diagnosis in females><diagnosis in women><diagnosis within females><diagnosis within women><dietary therapy><diverse populations><drug intervention><drug treatment><drug/agent><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><exhaustion><expectant mother><expectant women><expecting mother><expecting women><female diagnosis><fetus tissue><follow up><follow-up><followed up><followup><glycemic control><head-to-head analysis><head-to-head comparison><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><individuals who are pregnant><infantile hypoglycemia><investigate population><kids><long-term followup><long-term sequelae><machine based learning><maternal diabetes><maternal risk><member><nutritional care><nutritional therapy><obese children><obesity during childhood><obesity in children><obesity risk><observational research study><observational survey><ontogeny><optimal therapies><optimal treatments><overweight child><overweight childhood><pediatric obesity><people who are pregnant><perinatal complications><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><population diversity><population investigation><population level investigation><population specific research><post pregnancy><post-partum><pragmatic randomized trial><pregnancy diabetes><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prepregnancy obesity><preterm delivery><randomized control trial><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk for obesity><risk of obesity><risk-reducing><statistic methods><studies of populations><study of the population><study population><survey population><ten year old><ten years of age><those who are pregnant><treatment as usual><treatment strategy><trial comparing><usual care><women who are pregnant><women's diagnosis><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rebecca A. Krukowski

UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, COLUMBIA, SC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$667,573

FY 2026

Project Title

Addressing Rural Health Disparities by Optimizing "High Touch" Intervention Components in Digital Obesity Treatment

Grant Number:

5R01DK135227-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over 130 million individuals in the US have overweight and obesity, and rural communities experience significantly higher rates of obesity and related chronic diseases. Fortunately, weight losses of as little as 5-7% can ameliorate obesity-associated co-morbidities. Although lifestyle interventions ...

Research Terms

<21+ years old><Accountability><Address><Adult><Adult Human><After Care><After-Treatment><Aftercare><Age><Area><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body Weight decreased><Centers for Medicare and Medicaid Services><Chronic Disease><Chronic Illness><Clinical><Communities><Conditioning Therapy><Congresses><Counselor><County><Diabetes Mellitus><Dietary intake><E-Mail><Effectiveness><Electronic Mail><Elements><Email><Enrollment><Ethnic Origin><Ethnicity><Feedback><Geography><Health Care Financing Administration><Human><Human Resources><Individual><Informal Social Control><Internet><Intervention><Life Style><Lifestyle><Manpower><Mediator><Minority><Modern Man><Monitor><Motivation><Needles><Obesity><Outcome><Overweight><Participant><Persons><Physical activity><Pilot Projects><Policies><Population><Problem Solving><Process><Professional counselor><Public Health><Race><Races><Randomized><Research><Research Resources><Resources><Risk><Rural><Rural Community><Rural Population><Rural group><Rural people><Self Regulation><Site><Social support><Subgroup><Testing><Time><Touch><Touch sensation><United States><United States Centers for Medicare and Medicaid Services><United States Health Care Financing Administration><WWW><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Weight maintenance regimen><adiposity><adulthood><ages><behavior intervention><behavioral intervention><body weight gain><body weight increase><body weight loss><chronic disorder><co-morbid><co-morbidity><coaching calls><comorbidity><corpulence><cost><delivered remotely><diabetes><diabetes prevention program><digital><digital delivery><digital intervention><digital therapeutics><digital therapy><digital treatment><digitally deliver><disparity in health><electronic communication><enroll><ethnic minority><evidence base><experience><experiment><experimental research><experimental study><experiments><health disparity><implementation cost><implementation investment><life style intervention><lifestyle intervention><male><multiphase optimization strategy><obesity intervention><obesity therapy><obesity treatment><online intervention><personnel><phone coach><pilot study><post treatment><prevent><preventing><programs><racial><racial background><racial minority><racial origin><randomisation><randomization><randomly assigned><recruit><remote delivery><rural area><rural counties><rural dwellers><rural health disparities><rural individual><rural locality><rural location><rural place><rural region><rural resident><rural setting><sex><social support network><tactile sensation><telephone based coaching><telephone coaching><telephone counseling><therapy optimization><treatment optimization><treatment program><under served community><underserved community><video based session><video session><web><weight control><weight loss intervention><weight loss therapy><weight loss treatment><weight management><weights><world wide web><wt gain><wt-loss><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DELIA SMITH WEST

UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, COLUMBIA, SC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$667,573

FY 2026

Project Title

Addressing Rural Health Disparities by Optimizing "High Touch" Intervention Components in Digital Obesity Treatment

Grant Number:

5R01DK135227-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over 130 million individuals in the US have overweight and obesity, and rural communities experience significantly higher rates of obesity and related chronic diseases. Fortunately, weight losses of as little as 5-7% can ameliorate obesity-associated co-morbidities. Although lifestyle interventions ...

Research Terms

<21+ years old><Accountability><Address><Adult><Adult Human><After Care><After-Treatment><Aftercare><Age><Area><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body Weight decreased><Centers for Medicare and Medicaid Services><Chronic Disease><Chronic Illness><Clinical><Communities><Conditioning Therapy><Congresses><Counselor><County><Diabetes Mellitus><Dietary intake><E-Mail><Effectiveness><Electronic Mail><Elements><Email><Enrollment><Ethnic Origin><Ethnicity><Feedback><Geography><Health Care Financing Administration><Human><Human Resources><Individual><Informal Social Control><Internet><Intervention><Life Style><Lifestyle><Manpower><Mediator><Minority><Modern Man><Monitor><Motivation><Needles><Obesity><Outcome><Overweight><Participant><Persons><Physical activity><Pilot Projects><Policies><Population><Problem Solving><Process><Professional counselor><Public Health><Race><Races><Randomized><Research><Research Resources><Resources><Risk><Rural><Rural Community><Rural Population><Rural group><Rural people><Self Regulation><Site><Social support><Subgroup><Testing><Time><Touch><Touch sensation><United States><United States Centers for Medicare and Medicaid Services><United States Health Care Financing Administration><WWW><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Weight maintenance regimen><adiposity><adulthood><ages><behavior intervention><behavioral intervention><body weight gain><body weight increase><body weight loss><chronic disorder><co-morbid><co-morbidity><coaching calls><comorbidity><corpulence><cost><delivered remotely><diabetes><diabetes prevention program><digital><digital delivery><digital intervention><digital therapeutics><digital therapy><digital treatment><digitally deliver><disparity in health><electronic communication><enroll><ethnic minority><evidence base><experience><experiment><experimental research><experimental study><experiments><health disparity><implementation cost><implementation investment><life style intervention><lifestyle intervention><male><multiphase optimization strategy><obesity intervention><obesity therapy><obesity treatment><online intervention><personnel><phone coach><pilot study><post treatment><prevent><preventing><programs><racial><racial background><racial minority><racial origin><randomisation><randomization><randomly assigned><recruit><remote delivery><rural area><rural counties><rural dwellers><rural health disparities><rural individual><rural locality><rural location><rural place><rural region><rural resident><rural setting><sex><social support network><tactile sensation><telephone based coaching><telephone coaching><telephone counseling><therapy optimization><treatment optimization><treatment program><under served community><underserved community><video based session><video session><web><weight control><weight loss intervention><weight loss therapy><weight loss treatment><weight management><weights><world wide web><wt gain><wt-loss><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

WENDONG HUANG

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$665,898

FY 2026

Project Title

Targeting bile acid composition to treat metabolic diseases

Grant Number:

5R01DK138665-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/19/2024

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY In the US, 42.4% of the adults are classified as obese. Obesity associated metabolic diseases, including type 2 diabetes (T2D), nonalcoholic fatty liver disease (NAFLD) and its progressive stage nonalcoholic steatohepatitis (NASH), severely impact human quality of life and mortality....

Research Terms

<21+ years old><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affinity><Applications Grants><Assay><Bile Acids><Binding><Bioassay><Biochemical><Biological Assay><Body Weight decreased><CYP12><CYP8B1><CYP8B1 gene><Cell Communication and Signaling><Cell Function><Cell Line><Cell Physiology><Cell Process><Cell Signaling><CellLine><Cellular Function><Cellular Physiology><Cellular Process><Classification><Clinical><Coupled><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 Family Gene><Cytochrome P450, Subfamily VIIIB, Polypeptide 1><Detection><Drug Therapy><Drugs><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Epidemic><FDA licensed drugs><FDA-approved agents><FDA-approved drug><FDA-approved medications><FDA-approved pharmaceuticals><FDA-approved therapeutic agent><Family><Fatty Liver><Fatty Tissue><Food and Drug Administration approved drug><Food and Drug Administration approved medications><Food and Drug Administration approved pharmaceuticals><G-Proteins><GI microbiome><GPBAR1><GPBAR1 gene><GTP-Binding Proteins><GTP-Regulatory Proteins><Generalized Growth><Goals><Grant Proposals><Growth><Guanine Nucleotide Coupling Protein><Guanine Nucleotide Regulatory Proteins><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><High Throughput Assay><Human><Hydroxylation><Inflammation><Intestinal><Intestines><Intracellular Communication and Signaling><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Knowledge><Lead><Libraries><Liver><Liver Cells><Liver Steatosis><Maturity-Onset Diabetes Mellitus><Mediating><Medication><Metabolic><Metabolic Diseases><Metabolic Disorder><Methods><Mice><Mice Mammals><Mission><Modeling><Modern Man><Molecular Interaction><Murine><Mus><NAFLD><NASH><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non obese><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonobese><Null Mouse><Obesity><Outcome><Overweight><P450><Pb element><Persons><Pharmaceutical Agent><Pharmaceutical Preparations><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Pharmacological Treatment><Pharmacotherapy><Play><Production><Property><Proteins><Public Health><QOL><Quality of life><Receptor Protein><Research><Role><Safety><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Sterol 12-alpha-Hydroxylase><Strains Cell Lines><Structure><Structure-Activity Relationship><Subcellular Process><Systematics><T2 DM><T2D><T2DM><TGR5><Testing><Therapeutic Effect><Thesaurismosis><Tissue Growth><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Validation><Weight Loss><Weight Reduction><Wild Type Mouse><adipose><adiposity><adult onset diabetes><adulthood><biological signal transduction><body weight loss><bowel><candidate identification><chemical structure function><corpulence><cultured cell line><diabetic><diet-associated obesity><diet-induced obesity><diet-related obesity><digestive tract microbiome><disease model><disorder model><drug candidate><drug development><drug intervention><drug treatment><drug/agent><effective therapy><effective treatment><enteric microbiome><fat metabolism><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><gastrointestinal microbiome><glucose metabolism><gut microbiome><gut-associated microbiome><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><hepatic steatosis><hepatosteatosis><high throughput screening><hydrophilicity><improved><in vivo><inhibitor><inhibitor drug><inhibitor therapeutic><inhibitor therapy><innovate><innovation><innovative><insulin sensitivity><intestinal barrier><intestinal biome><intestinal microbiome><intestinal mucosal barrier><ketosis resistant diabetes><knock-down><knockdown><lead candidate><lipid metabolism><maturity onset diabetes><metabolism disorder><mortality><mouse model><murine model><non-alcohol fatty liver disease><non-alcohol induced steatohepatitis><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic fatty liver disease><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><novel><obesity intervention><obesity therapy><obesity treatment><ontogeny><pharmaceutical><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><polypeptide><receptor><side effect><social role><structure function relationship><therapeutic target><tool><treatment effect><type 2 DM><type II DM><type two diabetes><validations><white adipose tissue><wildtype mouse><wt-loss><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

John Jefferson Perry

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$665,898

FY 2026

Project Title

Targeting bile acid composition to treat metabolic diseases

Grant Number:

5R01DK138665-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/19/2024

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY In the US, 42.4% of the adults are classified as obese. Obesity associated metabolic diseases, including type 2 diabetes (T2D), nonalcoholic fatty liver disease (NAFLD) and its progressive stage nonalcoholic steatohepatitis (NASH), severely impact human quality of life and mortality....

Research Terms

<21+ years old><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affinity><Applications Grants><Assay><Bile Acids><Binding><Bioassay><Biochemical><Biological Assay><Body Weight decreased><CYP12><CYP8B1><CYP8B1 gene><Cell Communication and Signaling><Cell Function><Cell Line><Cell Physiology><Cell Process><Cell Signaling><CellLine><Cellular Function><Cellular Physiology><Cellular Process><Classification><Clinical><Coupled><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 Family Gene><Cytochrome P450, Subfamily VIIIB, Polypeptide 1><Detection><Drug Therapy><Drugs><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Epidemic><FDA licensed drugs><FDA-approved agents><FDA-approved drug><FDA-approved medications><FDA-approved pharmaceuticals><FDA-approved therapeutic agent><Family><Fatty Liver><Fatty Tissue><Food and Drug Administration approved drug><Food and Drug Administration approved medications><Food and Drug Administration approved pharmaceuticals><G-Proteins><GI microbiome><GPBAR1><GPBAR1 gene><GTP-Binding Proteins><GTP-Regulatory Proteins><Generalized Growth><Goals><Grant Proposals><Growth><Guanine Nucleotide Coupling Protein><Guanine Nucleotide Regulatory Proteins><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><High Throughput Assay><Human><Hydroxylation><Inflammation><Intestinal><Intestines><Intracellular Communication and Signaling><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Knowledge><Lead><Libraries><Liver><Liver Cells><Liver Steatosis><Maturity-Onset Diabetes Mellitus><Mediating><Medication><Metabolic><Metabolic Diseases><Metabolic Disorder><Methods><Mice><Mice Mammals><Mission><Modeling><Modern Man><Molecular Interaction><Murine><Mus><NAFLD><NASH><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non obese><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonobese><Null Mouse><Obesity><Outcome><Overweight><P450><Pb element><Persons><Pharmaceutical Agent><Pharmaceutical Preparations><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Pharmacological Treatment><Pharmacotherapy><Play><Production><Property><Proteins><Public Health><QOL><Quality of life><Receptor Protein><Research><Role><Safety><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Sterol 12-alpha-Hydroxylase><Strains Cell Lines><Structure><Structure-Activity Relationship><Subcellular Process><Systematics><T2 DM><T2D><T2DM><TGR5><Testing><Therapeutic Effect><Thesaurismosis><Tissue Growth><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Validation><Weight Loss><Weight Reduction><Wild Type Mouse><adipose><adiposity><adult onset diabetes><adulthood><biological signal transduction><body weight loss><bowel><candidate identification><chemical structure function><corpulence><cultured cell line><diabetic><diet-associated obesity><diet-induced obesity><diet-related obesity><digestive tract microbiome><disease model><disorder model><drug candidate><drug development><drug intervention><drug treatment><drug/agent><effective therapy><effective treatment><enteric microbiome><fat metabolism><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><gastrointestinal microbiome><glucose metabolism><gut microbiome><gut-associated microbiome><heavy metal Pb><heavy metal lead><hepatic body system><hepatic organ system><hepatic steatosis><hepatosteatosis><high throughput screening><hydrophilicity><improved><in vivo><inhibitor><inhibitor drug><inhibitor therapeutic><inhibitor therapy><innovate><innovation><innovative><insulin sensitivity><intestinal barrier><intestinal biome><intestinal microbiome><intestinal mucosal barrier><ketosis resistant diabetes><knock-down><knockdown><lead candidate><lipid metabolism><maturity onset diabetes><metabolism disorder><mortality><mouse model><murine model><non-alcohol fatty liver disease><non-alcohol induced steatohepatitis><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic fatty liver disease><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><novel><obesity intervention><obesity therapy><obesity treatment><ontogeny><pharmaceutical><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><polypeptide><receptor><side effect><social role><structure function relationship><therapeutic target><tool><treatment effect><type 2 DM><type II DM><type two diabetes><validations><white adipose tissue><wildtype mouse><wt-loss><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marian L. Fitzgibbon

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$665,368

FY 2026

Project Title

Weight management and Black American women: Targeting social networks as a strategy to improve outcomes

Grant Number:

5R01CA296842-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Obesity is linked with a variety of cancer types and is particularly prevalent among Black American (BA) women compared to other subgroups (57.2 5% for BAs). In weight management interventions, BA participants lose less weight than non-Hispanic whites. Obesity interventions co-created with ...

Research Terms

<21+ years old><Address><Adult><Adult Human><Age><Anatomic Sites><Anatomic structures><Anatomy><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Black American><Body Composition><Body Weight><Body Weight decreased><Body fat><Body mass index><Breast Cancer Risk Factor><Cancers><Characteristics><Communities><Data><Diet><Dietary quality><Disparities><Disparity><Education for Intervention><Educational Intervention><Evidence based intervention><Family><Friends><Gender><Health><Inequity><Information Dissemination><Information Management><Instruction Intervention><Intervention><Knowledge><Life Style><Lifestyle><Link><Malignant Neoplasms><Malignant Tumor><Mediterranean Diet><Methods><Modality><Modeling><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Obesity><Obesity associated cancer><Obesity related cancer><Outcome><Participant><Physical activity><Pilot Projects><Population><Position><Positioning Attribute><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Quetelet index><Race><Races><Randomized><Randomized, Controlled Trials><Research><Risk Behaviors><Risky Behavior><Role><Self Efficacy><Social Environment><Social Network><Subgroup><Survey Instrument><Surveys><Testing><Trainers Training><Training><Training Intervention><Weight><Weight Loss><Weight Reduction><Weight maintenance regimen><Woman><Work><acceptability and feasibility><adiposity><adulthood><after menopause><aged><ages><analytical method><at risk behavior><behavior change><body weight loss><breast cancer risk><cancer disparity><cancer health disparity><cancer prevention><cancer risk><cancer type><cancer-related health disparity><corpulence><cultural values><density><diet quality><diets><disparity in cancer><dissemination of results><evidence base><experience><following menopause><improved><improved outcome><information seeking behavior><innovate><innovation><innovative><instructional intervention><intervention design><intervention effect><intervention participants><interventions leveraging social networks><malignancy><member><neoplasm/cancer><new approaches><novel approaches><novel strategies><novel strategy><obesity intervention><obesity therapy><obesity treatment><older adult><older adulthood><participant engagement><past menopause><patient engagement><pilot study><post intervention><post-menopausal><postmenopausal><postmenopausal status><racial><racial background><racial origin><randomisation><randomization><randomized control trial><randomly assigned><response to therapy><response to treatment><self reported behavior><skills><social><social climate><social context><social network based intervention><social network intervention><social role><socioenvironment><socioenvironmental><therapeutic response><therapy design><therapy response><treatment design><treatment response><treatment responsiveness><trial comparing><weight control><weight loss intervention><weight loss therapy><weight loss treatment><weight management><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yamile Molina

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$665,368

FY 2026

Project Title

Weight management and Black American women: Targeting social networks as a strategy to improve outcomes

Grant Number:

5R01CA296842-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Obesity is linked with a variety of cancer types and is particularly prevalent among Black American (BA) women compared to other subgroups (57.2 5% for BAs). In weight management interventions, BA participants lose less weight than non-Hispanic whites. Obesity interventions co-created with ...

Research Terms

<21+ years old><Address><Adult><Adult Human><Age><Anatomic Sites><Anatomic structures><Anatomy><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Black American><Body Composition><Body Weight><Body Weight decreased><Body fat><Body mass index><Breast Cancer Risk Factor><Cancers><Characteristics><Communities><Data><Diet><Dietary quality><Disparities><Disparity><Education for Intervention><Educational Intervention><Evidence based intervention><Family><Friends><Gender><Health><Inequity><Information Dissemination><Information Management><Instruction Intervention><Intervention><Knowledge><Life Style><Lifestyle><Link><Malignant Neoplasms><Malignant Tumor><Mediterranean Diet><Methods><Modality><Modeling><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Obesity><Obesity associated cancer><Obesity related cancer><Outcome><Participant><Physical activity><Pilot Projects><Population><Position><Positioning Attribute><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Quetelet index><Race><Races><Randomized><Randomized, Controlled Trials><Research><Risk Behaviors><Risky Behavior><Role><Self Efficacy><Social Environment><Social Network><Subgroup><Survey Instrument><Surveys><Testing><Trainers Training><Training><Training Intervention><Weight><Weight Loss><Weight Reduction><Weight maintenance regimen><Woman><Work><acceptability and feasibility><adiposity><adulthood><after menopause><aged><ages><analytical method><at risk behavior><behavior change><body weight loss><breast cancer risk><cancer disparity><cancer health disparity><cancer prevention><cancer risk><cancer type><cancer-related health disparity><corpulence><cultural values><density><diet quality><diets><disparity in cancer><dissemination of results><evidence base><experience><following menopause><improved><improved outcome><information seeking behavior><innovate><innovation><innovative><instructional intervention><intervention design><intervention effect><intervention participants><interventions leveraging social networks><malignancy><member><neoplasm/cancer><new approaches><novel approaches><novel strategies><novel strategy><obesity intervention><obesity therapy><obesity treatment><older adult><older adulthood><participant engagement><past menopause><patient engagement><pilot study><post intervention><post-menopausal><postmenopausal><postmenopausal status><racial><racial background><racial origin><randomisation><randomization><randomized control trial><randomly assigned><response to therapy><response to treatment><self reported behavior><skills><social><social climate><social context><social network based intervention><social network intervention><social role><socioenvironment><socioenvironmental><therapeutic response><therapy design><therapy response><treatment design><treatment response><treatment responsiveness><trial comparing><weight control><weight loss intervention><weight loss therapy><weight loss treatment><weight management><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SHARON Marie DONOVAN

UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, CHAMPAIGN, IL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$660,357

FY 2026

Project Title

Elucidating Gene-Environment-Behavior Interactions to Uncover Causal Mechanisms for Obesity in Early Life

Grant Number:

5R01DK138032-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Trajectories leading to childhood obesity result from multifactorial Gene x Environment x Behavior interactions during a period of high developmental plasticity. Defining the causal mechanisms that mediate risk for obesity development in early life and how risk can be modified by psychosocial, conte...

Research Terms

<0-11 years old><5-HT><5-HT pathway><5-HT system><5-Hydroxytryptamine><5HT><5HT transporter><5HTT protein><Adipose tissue><Affect><Application Context><Bayesian Network><Behavior><Behavioral><Biological><Biological Markers><Birth><Body Composition><Child><Child Youth><Childhood><Children (0-21)><Computational Biology><Data><Data Set><Development><Diet><Diet Composition><Dietary Component><Dietary intake><Dimensions><EWAS><Eating><Eating Behavior><Emotional><Emotions><Enteramine><Environment><Environmental Factor><Environmental Risk Factor><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Evidence based practice guidelines><Exhibits><Fatty Tissue><Firmicutes><Food Intake><GI microbiome><GWA study><GWAS><Generalized Growth><Genes><Genetic><Genetic Diversity><Genetic Risk><Genetic Variation><Genome><Growth><Health><Hippophaine><Human><Individual><Inflammation><Informal Social Control><Intervention><Knowledge><Life><Link><Maps><Measures><Mediating><Methylation><Modeling><Modern Man><Network Analysis><Nutrition><Obesity><Outcome><Parturition><Pathway Analysis><Pathway interactions><Phenotype><Phylogenetic Analysis><Phylogenetics><Predisposition><Process><Psychosocial Factor><Questionnaires><Regulation><Research><Risk><Risk Factors><Risk-associated variant><Sampling><Self Regulation><Serotonergic System><Serotonin><Susceptibility><System><Systems Biology><Temperament><Testing><Time><Tissue Growth><Training><Tryptophan Metabolism><Tryptophan Metabolism Pathway><Variant><Variation><Weight><Weight Gain><Weight Increase><adipose><adiposity><algorithm development><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><body weight gain><body weight increase><child adiposity><child obesity><childhood adiposity><childhood obesity><cognitive control><cohort><community microbes><computer biology><contextual factors><corpulence><data integration><developmental><developmental plasticity><dietary><dietary composition><diets><digestive tract microbiome><dopamine system><dysbacteriosis><dysbiosis><dysbiotic><early childhood><early-life nutrition><enteric microbiome><environmental risk><epigenetically><epigenome><epigenome wide association analysis><epigenome-wide association studies><evidence based guidelines><evidence based recommendations><executive control><executive function><fast weight gain><fecal microbial community><fecal microbiota><gastrointestinal microbiome><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><gut microbiome><gut-associated microbiome><improved><indexing><individualized predictions><infancy><infantile><intestinal biome><intestinal microbiome><kids><microbe community><microbial><microbial community><microbial imbalance><microbiome><microbiome community composition><microbiome composition><microbiome species composition><microbiome structure><microbiota composition><microorganism community><network models><neural network><new approaches><novel><novel approaches><novel strategies><novel strategy><obese children><obesity development><obesity during childhood><obesity in children><obesity risk><ontogeny><pathway><pediatric><pediatric obesity><personalized predictions><polymicrobial community><precision nutrition><predict responsiveness><predicting response><prediction algorithm><prevent><preventing><psychosocial variables><rapid growth><rapid weight gain><risk allele><risk for obesity><risk gene><risk genotype><risk loci><risk locus><risk of obesity><risk variant><serotonergic pathway><serotonin pathway><serotonin system><serotonin transporter><sodium-dependent serotonin transporter><sudden weight gain><theories><weights><white adipose tissue><whole genome association analysis><whole genome association study><wt gain><yellow adipose tissue><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Fajun James Yang

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$655,481

FY 2026

Project Title

Regulation of adipose tissue remodeling by the CCNC-Mediator

Grant Number:

5R01DK139610-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract: Obesity has become a major health problem. In contrast to pathologic obesity, “metabolically healthy obesity” features less insulin resistance with more small adipocytes in subcutaneous adipose tissues. The inability to increase the adipocyte number has been proposed as a ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Judith Korner

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$653,119

FY 2026

Project Title

Association of genetic variation near the dopamine D2 receptor gene and other polymorphisms that modulate dopaminergic and opioid signaling on the weight loss response to naltrexone/bupropion

Grant Number:

5R01DK132527-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT The cornerstone of obesity therapy - diet, physical activity and behavioral modification - fails to produce sufficient long-term weight loss in most individuals. Clinical guidelines recommend the addition of anti-obesity medication (AOM) when conservative methods are less th...

Research Terms

<21+ years old><ACTH-beta-Lipotropin Precursor><ANK Domain><ANK Repeat><Address><Adult><Adult Human><Affect><Alleles><Allelomorphs><Amfebutamone><Ankyrin Repeat><Ankyrin Repeat Domain><Anti-Obesity Agents><Anti-Obesity Drugs><Appetite><BMI><BMI percentile><BMI z-score><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Binding><Biological Markers><Blood Serum><Body Weight><Body Weight decreased><Body mass index><Brain><Brain Nervous System><Bupropion><Causality><Cell Communication and Signaling><Cell Signaling><Clinical><Clinical Trials><Combined Modality Therapy><Conditioning Therapy><Corticotropin-beta-Lipotropin Precursor><Counseling><D(2) Dopamine Receptor Gene><D2 receptor><D2DR><D2DR Gene><D2R><D2R Gene><DRD2><DRD2 Receptor><DRD2 gene><Desire for food><Diet><Diet therapy><Dopamine><Dopamine D2 Receptor><Dopamine Receptor D2 Gene><Drug Therapy><Drugs><Eating><Encephalon><Endorphin-ACTH Precursor><Energy Expenditure><Energy Metabolism><Enrollment><Esthesia><Etiology><Exposure to><FDA approved><Food Intake><Gene variant><Genes><Genetic><Genetic Diversity><Genetic Markers><Genetic Polymorphism><Genetic Variation><Genotype><Goals><Guidelines><Heritability><Heterogeneity><Hydroxytyramine><Individual><Individual Differences><Intermediary Metabolism><Intracellular Communication and Signaling><Kinases><Knowledge><Learning><Levarterenol><Levonorepinephrine><Mammotropin><Measures><Medication><Medicine><Metabolic Processes><Metabolism><Methods><Molecular Interaction><Multimodal Therapy><Multimodal Treatment><Nalorex><Naltrexone><Nemexin><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Noradrenaline><Norepinephrine><Obesity><Opiate Receptors><Opiates><Opioid><Opioid Receptor><Other Genetics><Outcome><Participant><Patients><Pharmaceutical Preparations><Pharmacogenetics><Pharmacological Treatment><Pharmacotherapy><Phase><Phosphotransferase Gene><Phosphotransferases><Physical activity><Pilot Projects><Pituitary Lactogenic Hormone><Pituitary Mammotropic Hormone><Population><Pro-ACTH-Endorphin><Pro-Opio-Melanocortin><Pro-Opiocortin><Pro-Opiomelanocortin><Prolactin><Proopiocortin><Proopiomelanocortin><Proteins><Questionnaires><Quetelet index><ReVia><Recommendation><Rewards><Risk-associated variant><Sensation><Serum><Signal Transduction><Signal Transduction Systems><Signaling><Testing><Time><Transphosphorylases><Vivitrol><Weight><Weight Loss><Weight Reduction><Wellbutrin><adiposity><adulthood><allelic variant><antagonism><antagonist><anti-obesity compounds><anti-obesity medications><anti-obesity therapeutics><behavior intervention><behavior phenotype><behavioral intervention><behavioral phenotyping><bio-markers><biologic marker><biological signal transduction><biomarker><body weight loss><buproprion><causation><clinical significance><clinically significant><co-morbid><co-morbidity><combination therapy><combined modality treatment><combined treatment><comorbidity><corpulence><cost><density><dietary therapy><diets><disease causation><drug intervention><drug response prediction><drug treatment><drug/agent><enroll><fat and obesity-associated protein><fat mass and obesity-associated><fat mass and obesity-associated protein><gene biomarker><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic variant><improved><individual patient><individual response><individualized response><luteotropic hormone><luteotropin><multi-modal therapy><multi-modal treatment><neuronal><obesity intervention><obesity therapy><obesity treatment><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><pilot study><polymorphism><prevent><preventing><primary end point><primary endpoint><prospective><responders and non-responders><responders from non-responders><responders or non-responders><responders versus non-responders><responders vs non-responders><responders/nonresponders><response><reuptake><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><side effect><weight maintenance><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Julia Yue Cui

OREGON STATE UNIVERSITY, CORVALLIS, OR

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$645,113

FY 2026

Project Title

Developmental flame retardant exposure, gut microbiome, and obesity

Grant Number:

5R01ES030197-09

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/12/2025

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity and type-II diabetes are a pandemic, causing grave social and economic burdens in the United States. Epidemiological and animal studies showed that the flame retardants polybrominated diphenyl ethers (PBDEs) and a most widely used current PBDE-alternative – tetrabromobispheno...

Research Terms

<2,3,7,8-Tetrachlorodibenzo-p-dioxin Receptors><21+ years old><AH Receptors><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Animal Model><Animal Models and Related Studies><Animals><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-diabetic Agents><Anti-diabetic Drugs><Anti-inflammatory><Aryl Hydrocarbon Receptor><Behavioral><Blood Serum><CP34><CYP3><CYP3A><CYP3A4><CYP3A4 gene><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><ChIP Sequencing><ChIP-seq><ChIPseq><Chemicals><Complex><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 3A4><Cytochrome P450 Family Gene><Cytochrome P450, Subfamily IIIA, Polypeptide 4><Cytochrome P450PCN1><Development><Diabetes Mellitus><Diet><Dietary Factors><Dioxin Receptors><Disease><Disorder><Economic Burden><Effectiveness><Endocrine><Endocrine disruption><Environmental Factor><Environmental Risk Factor><Epidemiology><Exposure to><FAMILY III P450><Fire Retardants><Flame Retardants><Functional Metagenomics><GI microbiome><GI microbiota><Gastrointestinal microbiota><Gene Expression><Gene Modified><Genes><Genetic><Genotype><Germ-Free><Gestation><Glucocorticoid-Inducible P450><Grant><Hepatic><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><High Fat Diet><Human><Immune><Immunes><Indoles><Industrialization><Inflammation><Inflammatory><Injury to Liver><Intermediary Metabolism><Intervention><Intestinal><Intestinal Content><Intestinal Leakage><Intestines><Intracellular Communication and Signaling><Isotopes><Ketosis-Resistant Diabetes Mellitus><L-Tryptophan><Leaky Gut><Levotryptophan><Life><Link><Liver><Liver Cells><Maturity-Onset Diabetes Mellitus><Mediating><Mediator><Metabolic Processes><Metabolism><Metagenomics><Mice><Mice Mammals><Microbe><Modern Man><Murine><Mus><NIDDM><Nifedipine Oxidase><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Receptors><Nuclear Translocator><Obesity><Oral><Organ><Outcome><P450><P450C3><P450PCN1><PXR receptor><Pancreas><Pancreatic><Pathogenesis><Phenotype><Physiologic><Physiological><Polyaromatic Hydrocarbon Receptors><Pregnancy><Prevalence><Propionic Acids><Receptor Activation><Receptor Protein><Receptor Signaling><Research><Risk Factors><Role><Sampling><Serum><Short-Chain Fatty Acids><Shotgun Sequencing><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Steroid-Inducible P450- III><T2 DM><T2D><T2DM><TCDD Receptors><Testing><Thyroid Gland Hormone><Thyroid Hormones><Time><Transgenic Mice><Tryptophan><Tryptophan Metabolism><Tryptophan Metabolism Pathway><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Volatile Fatty Acids><Weaning><adiposity><adult adiposity><adult obesity><adult onset diabetes><adulthood><adults with obesity><ahr ligand><anti-diabetic><aryl hydrocarbon receptor ligand><biological signal transduction><bowel><bowel inflammation><cell type><chromatin immunoprecipitation coupled with sequencing><chromatin immunoprecipitation followed by sequencing><chromatin immunoprecipitation with sequencing><chromatin immunoprecipitation-seq><chromatin immunoprecipitation-sequencing><constitutive androstane receptor><corpulence><developmental><diabetes><diabetic><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><digestive tract microbiome><dysbacteriosis><dysbiosis><dysbiotic><early life exposure><endocrine disrupting><enteric microbial community><enteric microbiome><enteric microbiota><environmental risk><epidemiologic><epidemiological><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><gastrointestinal microbial flora><gastrointestinal microbiome><gene modification><genetically modified><gut community><gut dysbiosis><gut flora><gut inflammation><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiome><gut microbiota><gut microbiotic><gut microflora><gut-associated microbiome><gut-liver axis><hepatic body system><hepatic damage><hepatic injury><hepatic organ system><high risk><hormone metabolism><human model><inflamed bowel><inflamed gut><inflamed intestine><inflammation marker><inflammatory marker><intestinal biome><intestinal flora><intestinal inflammation><intestinal microbiome><intestinal microbiota><intestinal microflora><intestinal tract microflora><ketosis resistant diabetes><later in life><later life><lens><lenses><liver damage><liver injury><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><microbial><microbial imbalance><microbial signature><microbiome><mimicry><model of animal><model of human><mouse model><murine model><novel><obesigenic><obesogenic><offspring><pandemic><pandemic disease><polybrominated biphenyl ether><polybrominated diphenyl ether><postnatal><pregnane X receptor><prevent><preventing><propanoic acid><pup><receptor><remediation><response><social><social role><species difference><tetrabromobisphenol A><transcriptomics><type 2 DM><type II DM><type two diabetes><western diet><western-style diet><western-type diet>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Haiwei Gu

OREGON STATE UNIVERSITY, CORVALLIS, OR

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$645,113

FY 2026

Project Title

Developmental flame retardant exposure, gut microbiome, and obesity

Grant Number:

5R01ES030197-09

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/12/2025

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity and type-II diabetes are a pandemic, causing grave social and economic burdens in the United States. Epidemiological and animal studies showed that the flame retardants polybrominated diphenyl ethers (PBDEs) and a most widely used current PBDE-alternative – tetrabromobispheno...

Research Terms

<2,3,7,8-Tetrachlorodibenzo-p-dioxin Receptors><21+ years old><AH Receptors><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Animal Model><Animal Models and Related Studies><Animals><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-diabetic Agents><Anti-diabetic Drugs><Anti-inflammatory><Aryl Hydrocarbon Receptor><Behavioral><Blood Serum><CP34><CYP3><CYP3A><CYP3A4><CYP3A4 gene><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><ChIP Sequencing><ChIP-seq><ChIPseq><Chemicals><Complex><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 3A4><Cytochrome P450 Family Gene><Cytochrome P450, Subfamily IIIA, Polypeptide 4><Cytochrome P450PCN1><Development><Diabetes Mellitus><Diet><Dietary Factors><Dioxin Receptors><Disease><Disorder><Economic Burden><Effectiveness><Endocrine><Endocrine disruption><Environmental Factor><Environmental Risk Factor><Epidemiology><Exposure to><FAMILY III P450><Fire Retardants><Flame Retardants><Functional Metagenomics><GI microbiome><GI microbiota><Gastrointestinal microbiota><Gene Expression><Gene Modified><Genes><Genetic><Genotype><Germ-Free><Gestation><Glucocorticoid-Inducible P450><Grant><Hepatic><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><High Fat Diet><Human><Immune><Immunes><Indoles><Industrialization><Inflammation><Inflammatory><Injury to Liver><Intermediary Metabolism><Intervention><Intestinal><Intestinal Content><Intestinal Leakage><Intestines><Intracellular Communication and Signaling><Isotopes><Ketosis-Resistant Diabetes Mellitus><L-Tryptophan><Leaky Gut><Levotryptophan><Life><Link><Liver><Liver Cells><Maturity-Onset Diabetes Mellitus><Mediating><Mediator><Metabolic Processes><Metabolism><Metagenomics><Mice><Mice Mammals><Microbe><Modern Man><Murine><Mus><NIDDM><Nifedipine Oxidase><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Receptors><Nuclear Translocator><Obesity><Oral><Organ><Outcome><P450><P450C3><P450PCN1><PXR receptor><Pancreas><Pancreatic><Pathogenesis><Phenotype><Physiologic><Physiological><Polyaromatic Hydrocarbon Receptors><Pregnancy><Prevalence><Propionic Acids><Receptor Activation><Receptor Protein><Receptor Signaling><Research><Risk Factors><Role><Sampling><Serum><Short-Chain Fatty Acids><Shotgun Sequencing><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Steroid-Inducible P450- III><T2 DM><T2D><T2DM><TCDD Receptors><Testing><Thyroid Gland Hormone><Thyroid Hormones><Time><Transgenic Mice><Tryptophan><Tryptophan Metabolism><Tryptophan Metabolism Pathway><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Volatile Fatty Acids><Weaning><adiposity><adult adiposity><adult obesity><adult onset diabetes><adulthood><adults with obesity><ahr ligand><anti-diabetic><aryl hydrocarbon receptor ligand><biological signal transduction><bowel><bowel inflammation><cell type><chromatin immunoprecipitation coupled with sequencing><chromatin immunoprecipitation followed by sequencing><chromatin immunoprecipitation with sequencing><chromatin immunoprecipitation-seq><chromatin immunoprecipitation-sequencing><constitutive androstane receptor><corpulence><developmental><diabetes><diabetic><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><digestive tract microbiome><dysbacteriosis><dysbiosis><dysbiotic><early life exposure><endocrine disrupting><enteric microbial community><enteric microbiome><enteric microbiota><environmental risk><epidemiologic><epidemiological><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><gastrointestinal microbial flora><gastrointestinal microbiome><gene modification><genetically modified><gut community><gut dysbiosis><gut flora><gut inflammation><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiome><gut microbiota><gut microbiotic><gut microflora><gut-associated microbiome><gut-liver axis><hepatic body system><hepatic damage><hepatic injury><hepatic organ system><high risk><hormone metabolism><human model><inflamed bowel><inflamed gut><inflamed intestine><inflammation marker><inflammatory marker><intestinal biome><intestinal flora><intestinal inflammation><intestinal microbiome><intestinal microbiota><intestinal microflora><intestinal tract microflora><ketosis resistant diabetes><later in life><later life><lens><lenses><liver damage><liver injury><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><microbial><microbial imbalance><microbial signature><microbiome><mimicry><model of animal><model of human><mouse model><murine model><novel><obesigenic><obesogenic><offspring><pandemic><pandemic disease><polybrominated biphenyl ether><polybrominated diphenyl ether><postnatal><pregnane X receptor><prevent><preventing><propanoic acid><pup><receptor><remediation><response><social><social role><species difference><tetrabromobisphenol A><transcriptomics><type 2 DM><type II DM><type two diabetes><western diet><western-style diet><western-type diet>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sridhar Mani

OREGON STATE UNIVERSITY, CORVALLIS, OR

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$645,113

FY 2026

Project Title

Developmental flame retardant exposure, gut microbiome, and obesity

Grant Number:

5R01ES030197-09

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/12/2025

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Obesity and type-II diabetes are a pandemic, causing grave social and economic burdens in the United States. Epidemiological and animal studies showed that the flame retardants polybrominated diphenyl ethers (PBDEs) and a most widely used current PBDE-alternative – tetrabromobispheno...

Research Terms

<2,3,7,8-Tetrachlorodibenzo-p-dioxin Receptors><21+ years old><AH Receptors><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Animal Model><Animal Models and Related Studies><Animals><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-diabetic Agents><Anti-diabetic Drugs><Anti-inflammatory><Aryl Hydrocarbon Receptor><Behavioral><Blood Serum><CP34><CYP3><CYP3A><CYP3A4><CYP3A4 gene><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><ChIP Sequencing><ChIP-seq><ChIPseq><Chemicals><Complex><Cytochrome P-450><Cytochrome P-450 Enzyme System><Cytochrome P450><Cytochrome P450 3A4><Cytochrome P450 Family Gene><Cytochrome P450, Subfamily IIIA, Polypeptide 4><Cytochrome P450PCN1><Development><Diabetes Mellitus><Diet><Dietary Factors><Dioxin Receptors><Disease><Disorder><Economic Burden><Effectiveness><Endocrine><Endocrine disruption><Environmental Factor><Environmental Risk Factor><Epidemiology><Exposure to><FAMILY III P450><Fire Retardants><Flame Retardants><Functional Metagenomics><GI microbiome><GI microbiota><Gastrointestinal microbiota><Gene Expression><Gene Modified><Genes><Genetic><Genotype><Germ-Free><Gestation><Glucocorticoid-Inducible P450><Grant><Hepatic><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><High Fat Diet><Human><Immune><Immunes><Indoles><Industrialization><Inflammation><Inflammatory><Injury to Liver><Intermediary Metabolism><Intervention><Intestinal><Intestinal Content><Intestinal Leakage><Intestines><Intracellular Communication and Signaling><Isotopes><Ketosis-Resistant Diabetes Mellitus><L-Tryptophan><Leaky Gut><Levotryptophan><Life><Link><Liver><Liver Cells><Maturity-Onset Diabetes Mellitus><Mediating><Mediator><Metabolic Processes><Metabolism><Metagenomics><Mice><Mice Mammals><Microbe><Modern Man><Murine><Mus><NIDDM><Nifedipine Oxidase><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Receptors><Nuclear Translocator><Obesity><Oral><Organ><Outcome><P450><P450C3><P450PCN1><PXR receptor><Pancreas><Pancreatic><Pathogenesis><Phenotype><Physiologic><Physiological><Polyaromatic Hydrocarbon Receptors><Pregnancy><Prevalence><Propionic Acids><Receptor Activation><Receptor Protein><Receptor Signaling><Research><Risk Factors><Role><Sampling><Serum><Short-Chain Fatty Acids><Shotgun Sequencing><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Steroid-Inducible P450- III><T2 DM><T2D><T2DM><TCDD Receptors><Testing><Thyroid Gland Hormone><Thyroid Hormones><Time><Transgenic Mice><Tryptophan><Tryptophan Metabolism><Tryptophan Metabolism Pathway><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Volatile Fatty Acids><Weaning><adiposity><adult adiposity><adult obesity><adult onset diabetes><adulthood><adults with obesity><ahr ligand><anti-diabetic><aryl hydrocarbon receptor ligand><biological signal transduction><bowel><bowel inflammation><cell type><chromatin immunoprecipitation coupled with sequencing><chromatin immunoprecipitation followed by sequencing><chromatin immunoprecipitation with sequencing><chromatin immunoprecipitation-seq><chromatin immunoprecipitation-sequencing><constitutive androstane receptor><corpulence><developmental><diabetes><diabetic><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><digestive tract microbiome><dysbacteriosis><dysbiosis><dysbiotic><early life exposure><endocrine disrupting><enteric microbial community><enteric microbiome><enteric microbiota><environmental risk><epidemiologic><epidemiological><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><gastrointestinal microbial flora><gastrointestinal microbiome><gene modification><genetically modified><gut community><gut dysbiosis><gut flora><gut inflammation><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiome><gut microbiota><gut microbiotic><gut microflora><gut-associated microbiome><gut-liver axis><hepatic body system><hepatic damage><hepatic injury><hepatic organ system><high risk><hormone metabolism><human model><inflamed bowel><inflamed gut><inflamed intestine><inflammation marker><inflammatory marker><intestinal biome><intestinal flora><intestinal inflammation><intestinal microbiome><intestinal microbiota><intestinal microflora><intestinal tract microflora><ketosis resistant diabetes><later in life><later life><lens><lenses><liver damage><liver injury><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><microbial><microbial imbalance><microbial signature><microbiome><mimicry><model of animal><model of human><mouse model><murine model><novel><obesigenic><obesogenic><offspring><pandemic><pandemic disease><polybrominated biphenyl ether><polybrominated diphenyl ether><postnatal><pregnane X receptor><prevent><preventing><propanoic acid><pup><receptor><remediation><response><social><social role><species difference><tetrabromobisphenol A><transcriptomics><type 2 DM><type II DM><type two diabetes><western diet><western-style diet><western-type diet>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

VICTORIA A CATENACCI

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$644,770

FY 2026

Project Title

Novel dietary interventions for reducing obesity-associated breast cancer

Grant Number:

5R01CA258766-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Despite new treatment modalities, the incidence of breast cancer has remained steady in recent years with >250,000 new diagnoses and >40,000 deaths annually in the US. Concurrently, the proportion of US women with overweight or obesity continues to rise, and is approaching 70%. Obesi...

Research Terms

<21+ years old><Acceleration><Adherence><Adipocytes><Adipose Cell><Adult><Adult Human><Adverse effects><Affect><Age><Anti-estrogen Therapy><Attention><Attenuated><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biological><Biological Markers><Body Weight decreased><Breast Cancer><Breast Cancer Patient><Breast Cancer Prevention><Breast Cancer Risk Factor><Breast Cancer survivor><Breast Neoplasms><Breast PDX models><Breast Tumor Patient><Breast Tumors><Caloric Restriction><Cancer Control><Cancer Control Science><Cancers><Cell Body><Cell-Extracellular Matrix><Cells><Cessation of life><Characteristics><Clinical><Clinical Research><Clinical Study><Conditioning Therapy><Data><Death><Development><Diathesis><Dietary Intervention><Disease><Disease susceptibility><Disorder><ECM><ER Positive><ER+><Endocrine Therapy><Estrogen receptor positive><Estrogens><Extracellular Matrix><Face><Fat Cells><Fibroblasts><Foundations><Future><Generalized Growth><Growth><Health><Health Benefit><Hormonal Therapy><Human><Immune><Immunes><Incidence><Individual><Inflammatory><Intermittent fasting><Intervention><Intervention Studies><Intervention Trial><Interventional trial><Investigators><Lead><Leanness><Life Style><Lifestyle><Lipocytes><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mammary Cancer><Mammary Neoplasms><Mature Lipocyte><Mature fat cell><Mediator><Medical Oncology><Menopausal Status><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Modality><Modeling><Modern Man><Neoplasm Metastasis><Newly Diagnosed><Nutrition><Nutrition Interventions><Nutritional Interventions><Obesity><Outcome><Overweight><PDX model><Patient derived xenograft><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patient-derived xenograft models of breast cancer><Patients><Pb element><Persons><Phase><Play><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Pre-Menopause><Pre-menopausal Period><Predisposition><Premenopausal><Premenopausal Period><Premenopause><Prognosis><Protein Secretion><QOL><Quality of life><Randomized><Research Personnel><Researchers><Resistance development><Resistant development><Risk><Role><Science><Secondary Neoplasm><Secondary Tumor><Specific qualifier value><Specified><Stromal Cells><Structure><Susceptibility><TNBC><Therapeutic Estrogen><Thesaurismosis><Thinness><Time><Time-restricted eating><Time-restricted feeding><Tissue Growth><Translating><Tumor Promotion><Tumor Subtype><Weight><Weight Loss><Weight Reduction><Woman><Work><adiposity><adulthood><after menopause><ages><attenuate><attenuates><behavior intervention><behavioral intervention><bio-markers><biologic><biologic marker><biomarker><body weight loss><breast cancer PDX><breast cancer diagnosis><breast cancer patient-derived xenograft><breast cancer progression><breast cancer risk><calorie restriction><cancer metastasis><cancer microenvironment><cancer progression><cancer risk><cancer sub-types><cancer subtypes><circulating biomarkers><circulating markers><clinical relevance><clinically relevant><common treatment><corpulence><developing resistance><developmental><diet intervention><dietary><efficacy trial><epidemiology research study><epidemiology study><epidemiology survey><faces><facial><female outcomes><following menopause><heavy metal Pb><heavy metal lead><hormone therapy><improved><improved outcome><individuals with breast cancer><innovate><innovation><innovative><interdisciplinary collaboration><intervention delivery><intervention refinement><intervention research><interventional research><interventional study><interventions research><liability to disease><malignancy><malignant breast tumor><mammary><mammary cancer prevention><mammary tumor><mammary tumor prevention><metabolism disorder><neoplasm progression><neoplasm/cancer><neoplastic progression><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><obesity intervention><obesity therapy><obesity treatment><ontogeny><outcomes among females><outcomes among women><outcomes in females><outcomes in women><past menopause><patient derived xenograft model><patient oriented outcomes><patient population><patients with breast cancer><person with breast cancer><post-menopausal><postmenopausal><postmenopausal status><pre-clinical study><pre-menopausal><preclinical study><premenopausal status><prevent breast cancer><randomisation><randomization><randomly assigned><social role><therapeutic outcome><therapy outcome><transdisciplinary collaboration><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor cell metastasis><tumor microenvironment><tumor progression><weight loss intervention><weight loss therapy><weight loss treatment><weights><women's outcomes><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Peter Kabos

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$644,770

FY 2026

Project Title

Novel dietary interventions for reducing obesity-associated breast cancer

Grant Number:

5R01CA258766-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Despite new treatment modalities, the incidence of breast cancer has remained steady in recent years with >250,000 new diagnoses and >40,000 deaths annually in the US. Concurrently, the proportion of US women with overweight or obesity continues to rise, and is approaching 70%. Obesi...

Research Terms

<21+ years old><Acceleration><Adherence><Adipocytes><Adipose Cell><Adult><Adult Human><Adverse effects><Affect><Age><Anti-estrogen Therapy><Attention><Attenuated><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biological><Biological Markers><Body Weight decreased><Breast Cancer><Breast Cancer Patient><Breast Cancer Prevention><Breast Cancer Risk Factor><Breast Cancer survivor><Breast Neoplasms><Breast PDX models><Breast Tumor Patient><Breast Tumors><Caloric Restriction><Cancer Control><Cancer Control Science><Cancers><Cell Body><Cell-Extracellular Matrix><Cells><Cessation of life><Characteristics><Clinical><Clinical Research><Clinical Study><Conditioning Therapy><Data><Death><Development><Diathesis><Dietary Intervention><Disease><Disease susceptibility><Disorder><ECM><ER Positive><ER+><Endocrine Therapy><Estrogen receptor positive><Estrogens><Extracellular Matrix><Face><Fat Cells><Fibroblasts><Foundations><Future><Generalized Growth><Growth><Health><Health Benefit><Hormonal Therapy><Human><Immune><Immunes><Incidence><Individual><Inflammatory><Intermittent fasting><Intervention><Intervention Studies><Intervention Trial><Interventional trial><Investigators><Lead><Leanness><Life Style><Lifestyle><Lipocytes><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mammary Cancer><Mammary Neoplasms><Mature Lipocyte><Mature fat cell><Mediator><Medical Oncology><Menopausal Status><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Modality><Modeling><Modern Man><Neoplasm Metastasis><Newly Diagnosed><Nutrition><Nutrition Interventions><Nutritional Interventions><Obesity><Outcome><Overweight><PDX model><Patient derived xenograft><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patient-derived xenograft models of breast cancer><Patients><Pb element><Persons><Phase><Play><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Pre-Menopause><Pre-menopausal Period><Predisposition><Premenopausal><Premenopausal Period><Premenopause><Prognosis><Protein Secretion><QOL><Quality of life><Randomized><Research Personnel><Researchers><Resistance development><Resistant development><Risk><Role><Science><Secondary Neoplasm><Secondary Tumor><Specific qualifier value><Specified><Stromal Cells><Structure><Susceptibility><TNBC><Therapeutic Estrogen><Thesaurismosis><Thinness><Time><Time-restricted eating><Time-restricted feeding><Tissue Growth><Translating><Tumor Promotion><Tumor Subtype><Weight><Weight Loss><Weight Reduction><Woman><Work><adiposity><adulthood><after menopause><ages><attenuate><attenuates><behavior intervention><behavioral intervention><bio-markers><biologic><biologic marker><biomarker><body weight loss><breast cancer PDX><breast cancer diagnosis><breast cancer patient-derived xenograft><breast cancer progression><breast cancer risk><calorie restriction><cancer metastasis><cancer microenvironment><cancer progression><cancer risk><cancer sub-types><cancer subtypes><circulating biomarkers><circulating markers><clinical relevance><clinically relevant><common treatment><corpulence><developing resistance><developmental><diet intervention><dietary><efficacy trial><epidemiology research study><epidemiology study><epidemiology survey><faces><facial><female outcomes><following menopause><heavy metal Pb><heavy metal lead><hormone therapy><improved><improved outcome><individuals with breast cancer><innovate><innovation><innovative><interdisciplinary collaboration><intervention delivery><intervention refinement><intervention research><interventional research><interventional study><interventions research><liability to disease><malignancy><malignant breast tumor><mammary><mammary cancer prevention><mammary tumor><mammary tumor prevention><metabolism disorder><neoplasm progression><neoplasm/cancer><neoplastic progression><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><obesity intervention><obesity therapy><obesity treatment><ontogeny><outcomes among females><outcomes among women><outcomes in females><outcomes in women><past menopause><patient derived xenograft model><patient oriented outcomes><patient population><patients with breast cancer><person with breast cancer><post-menopausal><postmenopausal><postmenopausal status><pre-clinical study><pre-menopausal><preclinical study><premenopausal status><prevent breast cancer><randomisation><randomization><randomly assigned><social role><therapeutic outcome><therapy outcome><transdisciplinary collaboration><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor cell metastasis><tumor microenvironment><tumor progression><weight loss intervention><weight loss therapy><weight loss treatment><weights><women's outcomes><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Paul S. Maclean

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$644,770

FY 2026

Project Title

Novel dietary interventions for reducing obesity-associated breast cancer

Grant Number:

5R01CA258766-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Despite new treatment modalities, the incidence of breast cancer has remained steady in recent years with >250,000 new diagnoses and >40,000 deaths annually in the US. Concurrently, the proportion of US women with overweight or obesity continues to rise, and is approaching 70%. Obesi...

Research Terms

<21+ years old><Acceleration><Adherence><Adipocytes><Adipose Cell><Adult><Adult Human><Adverse effects><Affect><Age><Anti-estrogen Therapy><Attention><Attenuated><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biological><Biological Markers><Body Weight decreased><Breast Cancer><Breast Cancer Patient><Breast Cancer Prevention><Breast Cancer Risk Factor><Breast Cancer survivor><Breast Neoplasms><Breast PDX models><Breast Tumor Patient><Breast Tumors><Caloric Restriction><Cancer Control><Cancer Control Science><Cancers><Cell Body><Cell-Extracellular Matrix><Cells><Cessation of life><Characteristics><Clinical><Clinical Research><Clinical Study><Conditioning Therapy><Data><Death><Development><Diathesis><Dietary Intervention><Disease><Disease susceptibility><Disorder><ECM><ER Positive><ER+><Endocrine Therapy><Estrogen receptor positive><Estrogens><Extracellular Matrix><Face><Fat Cells><Fibroblasts><Foundations><Future><Generalized Growth><Growth><Health><Health Benefit><Hormonal Therapy><Human><Immune><Immunes><Incidence><Individual><Inflammatory><Intermittent fasting><Intervention><Intervention Studies><Intervention Trial><Interventional trial><Investigators><Lead><Leanness><Life Style><Lifestyle><Lipocytes><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mammary Cancer><Mammary Neoplasms><Mature Lipocyte><Mature fat cell><Mediator><Medical Oncology><Menopausal Status><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Modality><Modeling><Modern Man><Neoplasm Metastasis><Newly Diagnosed><Nutrition><Nutrition Interventions><Nutritional Interventions><Obesity><Outcome><Overweight><PDX model><Patient derived xenograft><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patient-derived xenograft models of breast cancer><Patients><Pb element><Persons><Phase><Play><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Pre-Menopause><Pre-menopausal Period><Predisposition><Premenopausal><Premenopausal Period><Premenopause><Prognosis><Protein Secretion><QOL><Quality of life><Randomized><Research Personnel><Researchers><Resistance development><Resistant development><Risk><Role><Science><Secondary Neoplasm><Secondary Tumor><Specific qualifier value><Specified><Stromal Cells><Structure><Susceptibility><TNBC><Therapeutic Estrogen><Thesaurismosis><Thinness><Time><Time-restricted eating><Time-restricted feeding><Tissue Growth><Translating><Tumor Promotion><Tumor Subtype><Weight><Weight Loss><Weight Reduction><Woman><Work><adiposity><adulthood><after menopause><ages><attenuate><attenuates><behavior intervention><behavioral intervention><bio-markers><biologic><biologic marker><biomarker><body weight loss><breast cancer PDX><breast cancer diagnosis><breast cancer patient-derived xenograft><breast cancer progression><breast cancer risk><calorie restriction><cancer metastasis><cancer microenvironment><cancer progression><cancer risk><cancer sub-types><cancer subtypes><circulating biomarkers><circulating markers><clinical relevance><clinically relevant><common treatment><corpulence><developing resistance><developmental><diet intervention><dietary><efficacy trial><epidemiology research study><epidemiology study><epidemiology survey><faces><facial><female outcomes><following menopause><heavy metal Pb><heavy metal lead><hormone therapy><improved><improved outcome><individuals with breast cancer><innovate><innovation><innovative><interdisciplinary collaboration><intervention delivery><intervention refinement><intervention research><interventional research><interventional study><interventions research><liability to disease><malignancy><malignant breast tumor><mammary><mammary cancer prevention><mammary tumor><mammary tumor prevention><metabolism disorder><neoplasm progression><neoplasm/cancer><neoplastic progression><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><obesity intervention><obesity therapy><obesity treatment><ontogeny><outcomes among females><outcomes among women><outcomes in females><outcomes in women><past menopause><patient derived xenograft model><patient oriented outcomes><patient population><patients with breast cancer><person with breast cancer><post-menopausal><postmenopausal><postmenopausal status><pre-clinical study><pre-menopausal><preclinical study><premenopausal status><prevent breast cancer><randomisation><randomization><randomly assigned><social role><therapeutic outcome><therapy outcome><transdisciplinary collaboration><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor cell metastasis><tumor microenvironment><tumor progression><weight loss intervention><weight loss therapy><weight loss treatment><weights><women's outcomes><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christopher A Gaulke

UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, CHAMPAIGN, IL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$643,212

FY 2026

Project Title

Defining the impact of developmental herbicide exposures on gut microbiome physiology and interactions with health

Grant Number:

5R01ES036174-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/5/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

This project will define how interactions between herbicide exposure, the microbiome, and the host promote adiposity. Billions worldwide are overweight or obese. The gut microbiota regulate host energy metabolism, and imbalance in these communities correlates with increased body mass, adiposity, and...

Research Terms

<2,4-D><2,4-Dichlorophenoxyacetic Acid><Acceleration><Acute><Agricultural Chemicals><Agrochemicals><Animals><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Atrazine><Awareness><BMI><BMI percentile><BMI z-score><Body mass index><Brachydanio rerio><Caloric Intake><Cell Culture Techniques><Chemicals><Communities><Danio rerio><Data><Development><Developmental Diagnostic><Dose><Drug Metabolic Detoxication><Drug Metabolic Detoxification><Early Diagnosis><Early Intervention><Endocrine disruption><Energy Expenditure><Energy Intake><Energy Metabolism><Environment><Exposure to><Functional Metagenomics><GI microbiome><GI microbiota><Gastrointestinal microbiota><Genes><Germ-Free><Gnotobiotic><Gnotobiotics><Goals><Health><Herbicides><Image><Individual><Intermediary Metabolism><Life><Link><Mammalia><Mammalian Cell><Mammals><Measurement><Measures><Mediating><Mediation><Metabolic Drug Detoxications><Metabolic Processes><Metabolism><Metabolism of Toxic Agents><Metagenomics><Microbe><Microbiomics><Miscellaneous Antibiotic><Modeling><Molecular><Multiomic Data><N-(phosphonomethyl)glycine><Negotiating><Negotiation><Obesity><Overweight><PPAR gamma><PPAR-g><PPAR-γ><PPARgamma><PPARγ><Pathway interactions><Pattern><Peroxisome Proliferative Activated Receptor Gamma><Peroxisome Proliferator-Activated Receptor gamma><Peroxisome Proliferator-Activated Receptor γ><Persons><Phenotype><Physiologic><Physiological><Physiology><Quetelet index><Research><Resistance><Role><Sample Size><Series><Shapes><Shotguns><System><Testing><Therapeutic><Thiazolidinedione Receptor><Toxicology><Weight><Weight Gain><Weight Increase><Weights and Measures><Work><Zebra Danio><Zebra Fish><Zebrafish><acute toxicity><adipogenesis><adiposity><body weight gain><body weight increase><caloric dietary content><candidate identification><cell culture><cell cultures><community microbes><corpulence><detoxification><developmental><diagnostic biomarker><diagnostic marker><diet-associated obesity><diet-induced obesity><diet-related obesity><digestive tract microbiome><early detection><early life exposure><endocrine disrupting><enteric microbial community><enteric microbiome><enteric microbiota><experiment><experimental research><experimental study><experiments><fat metabolism><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><gastrointestinal microbial flora><gastrointestinal microbiome><gliphosate><glyphosate><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiome><gut microbiota><gut microbiotic><gut microflora><gut-associated microbiome><hazard><imaging><in vitro Assay><in vivo><innovate><innovation><innovative><insight><intestinal biome><intestinal flora><intestinal microbiome><intestinal microbiota><intestinal microflora><intestinal tract microflora><later in life><later life><life span><lifespan><lipid biosynthesis><lipid metabolism><lipogenesis><metabolism measurement><metabolomics><metabonomics><metagenome sequencing><metagenomic sequencing><metatranscriptomics><microbe community><microbial><microbial community><microbial consortia><microbial flora><microbial genomics><microbial products><microbiome><microbiome research><microbiome science><microbiome studies><microbiome transplant><microbiome transplantation><microbiota><microbiota transplant><microbiota transplantation><microflora><microorganism community><multiomics><multiple omic data><multiple omics><multispecies consortia><obese individuals><obese people><obese person><obese population><obese subjects><obesigenic><obesity development><obesity management><obesity prevention><obesity risk><obesogenic><operation><operations><panomics><pathway><polymicrobial community><prevent><prevent obesity><preventing><resilience><resilient><resistant><risk for obesity><risk mitigation><risk of obesity><shot gun><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><weights><wt gain>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stephen D Hursting

PURDUE UNIVERSITY, WEST LAFAYETTE, IN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$641,634

FY 2026

Project Title

Impact of hypoxia on lipid metabolism in obesity-driven breast cancer progression

Grant Number:

5R01CA271597-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/28/2022

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY While significant evidence has demonstrated that obesity increases the risk of metastasis, the molecular mechanisms by which obesity contributes to the metastatic progression of breast cancer are unclear. Furthermore, recent research in cancer development and progression has highligh...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dorothy Teegarden

PURDUE UNIVERSITY, WEST LAFAYETTE, IN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$641,634

FY 2026

Project Title

Impact of hypoxia on lipid metabolism in obesity-driven breast cancer progression

Grant Number:

5R01CA271597-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/28/2022

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY While significant evidence has demonstrated that obesity increases the risk of metastasis, the molecular mechanisms by which obesity contributes to the metastatic progression of breast cancer are unclear. Furthermore, recent research in cancer development and progression has highligh...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael Keith Wendt

PURDUE UNIVERSITY, WEST LAFAYETTE, IN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$641,634

FY 2026

Project Title

Impact of hypoxia on lipid metabolism in obesity-driven breast cancer progression

Grant Number:

5R01CA271597-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/28/2022

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY While significant evidence has demonstrated that obesity increases the risk of metastasis, the molecular mechanisms by which obesity contributes to the metastatic progression of breast cancer are unclear. Furthermore, recent research in cancer development and progression has highligh...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KAREN C JOHNSON

UNIVERSITY OF TENNESSEE HEALTH SCI CTR, MEMPHIS, TN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$639,038

FY 2026

Project Title

Managing Obesity by Leveraging Health Information Technology to Lower Cancer Risk

Grant Number:

5R01CA267643-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/14/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity is an important risk factor for many serious diseases including many types of cancer.2-36 In the United States, obesity disproportionally affects different population groups such as racial and ethnic minorities, persons with lower socioeconomic status, and persons living in rural areas.1,37,...

Research Terms

<21+ years old><Address><Adult><Adult Human><Affect><Area><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body Weight Changes><Body Weight decreased><Cancers><Clinical Practice Guideline><Clinical Trials><Collaborations><Communities><Conditioning Therapy><Diabetes Mellitus><Diet><Disease><Disorder><Effectiveness><Electronic Health Record><Enrollment><Funding><Goals><Group Practice><Guidelines><Health><Health Care Providers><Health Care Systems><Health Personnel><Health Sciences><Incidence><Individuals from minority><Individuals of minority><Intervention><Intervention Studies><Investigators><Knowledge><Low income><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Malignant Neoplasms><Malignant Tumor><Managed Care><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Modeling><NIH><National Institutes of Health><Obesity><Obesity associated cancer><Obesity related cancer><Outcome><Overweight><Participant><Patients><Persons><Phone><Physical activity><Physicians><Population><Population Group><Protocol><Protocols documentation><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Recommendation><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Proposals><Research Resources><Researchers><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Resources><Risk><Risk Factors><Risk Reduction><Site><Social Support System><Support System><System><Target Populations><Technology><Telephone><Tennessee><Testing><Time><Touch><Touch sensation><Training><Translating><United States><United States National Institutes of Health><Universities><Weight Change><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Weight maintenance regimen><Work><access to health care><accessibility of health care><accessibility to health care><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><behavior change><behavior intervention><behavioral intervention><body weight gain><body weight increase><body weight loss><cancer risk><cancer type><care resources><clinical practice><clinical practice and guidelines><comparator group><compare intervention><comparison group><comparison intervention><corpulence><cost effective><diabetes><diets><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><ethnic minority><formative assessment><formative evaluation><group intervention><health IT><health care access><health care availability><health care personnel><health care resources><health care service access><health care service availability><health care worker><health determinants><health information technology><health provider><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><healthy lifestyle><high risk><innovate><innovation><innovative><intervention refinement><intervention research><interventional research><interventional study><interventions research><life style intervention><lifestyle intervention><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><malignancy><medical care providers><medical personnel><neoplasm/cancer><obesity intervention><obesity management><obesity risk><obesity therapy><obesity treatment><patient health information><patient health record><patient medical record><patient portal><primary care setting><primary outcome><racial minority><randomisation><randomization><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk for obesity><risk of obesity><risk-reducing><rural area><rural locality><rural location><rural place><rural region><rural setting><success><tactile sensation><tool><treatment provider><uptake><urban area><urban environment><urban location><urban region><urban setting><weight control><weight loss intervention><weight loss program><weight loss programming><weight loss therapy><weight loss treatment><weight management><wt gain><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PHYLLIS A RICHEY

UNIVERSITY OF TENNESSEE HEALTH SCI CTR, MEMPHIS, TN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$639,038

FY 2026

Project Title

Managing Obesity by Leveraging Health Information Technology to Lower Cancer Risk

Grant Number:

5R01CA267643-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/14/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity is an important risk factor for many serious diseases including many types of cancer.2-36 In the United States, obesity disproportionally affects different population groups such as racial and ethnic minorities, persons with lower socioeconomic status, and persons living in rural areas.1,37,...

Research Terms

<21+ years old><Address><Adult><Adult Human><Affect><Area><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body Weight Changes><Body Weight decreased><Cancers><Clinical Practice Guideline><Clinical Trials><Collaborations><Communities><Conditioning Therapy><Diabetes Mellitus><Diet><Disease><Disorder><Effectiveness><Electronic Health Record><Enrollment><Funding><Goals><Group Practice><Guidelines><Health><Health Care Providers><Health Care Systems><Health Personnel><Health Sciences><Incidence><Individuals from minority><Individuals of minority><Intervention><Intervention Studies><Investigators><Knowledge><Low income><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Malignant Neoplasms><Malignant Tumor><Managed Care><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Modeling><NIH><National Institutes of Health><Obesity><Obesity associated cancer><Obesity related cancer><Outcome><Overweight><Participant><Patients><Persons><Phone><Physical activity><Physicians><Population><Population Group><Protocol><Protocols documentation><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Recommendation><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Proposals><Research Resources><Researchers><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Resources><Risk><Risk Factors><Risk Reduction><Site><Social Support System><Support System><System><Target Populations><Technology><Telephone><Tennessee><Testing><Time><Touch><Touch sensation><Training><Translating><United States><United States National Institutes of Health><Universities><Weight Change><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Weight maintenance regimen><Work><access to health care><accessibility of health care><accessibility to health care><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><behavior change><behavior intervention><behavioral intervention><body weight gain><body weight increase><body weight loss><cancer risk><cancer type><care resources><clinical practice><clinical practice and guidelines><comparator group><compare intervention><comparison group><comparison intervention><corpulence><cost effective><diabetes><diets><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><ethnic minority><formative assessment><formative evaluation><group intervention><health IT><health care access><health care availability><health care personnel><health care resources><health care service access><health care service availability><health care worker><health determinants><health information technology><health provider><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><healthy lifestyle><high risk><innovate><innovation><innovative><intervention refinement><intervention research><interventional research><interventional study><interventions research><life style intervention><lifestyle intervention><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><malignancy><medical care providers><medical personnel><neoplasm/cancer><obesity intervention><obesity management><obesity risk><obesity therapy><obesity treatment><patient health information><patient health record><patient medical record><patient portal><primary care setting><primary outcome><racial minority><randomisation><randomization><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk for obesity><risk of obesity><risk-reducing><rural area><rural locality><rural location><rural place><rural region><rural setting><success><tactile sensation><tool><treatment provider><uptake><urban area><urban environment><urban location><urban region><urban setting><weight control><weight loss intervention><weight loss program><weight loss programming><weight loss therapy><weight loss treatment><weight management><wt gain><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tanya Lynn Alderete

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$632,567

FY 2026

Project Title

Perfluoroalkyl Substances and the Gut Microbiome and Fecal Metabolome: Implications for Obesity Risk in Hispanic Children

Grant Number:

5R01ES035035-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Childhood obesity is a high priority public health issue as it increases the risk of co-morbid diseases, including cardiovascular disease, fatty liver disease, and type 2 diabetes. An improved understanding of the factors that trigger the development of early life obesity is urgently needed...

Research Terms

<0-11 years old><0-4 weeks old><2 year old><2 years of age><21+ years old><Actinomyces><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><Age Months><Amino Acids><Archives><BMI><BMI percentile><BMI z-score><Bacteria><Bacteroides><Bile Acids><Biological><Blood><Blood Reticuloendothelial System><Body mass index><Breast Cancer Detection><Breast Feeding><Breast Milk><Breast cancer screening><Breast screening><Breastmilk><California><Canada><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Chemicals><Child><Child Youth><Childhood><Children (0-21)><Data><Development><Disease><Disorder><Dryness><Event><Excretory function><Exposure to><Feeding behaviors><Functional Metagenomics><Funding><Future><GI microbiome><GI microbiota><Gastrointestinal microbiota><Generalized Growth><Gestation><Goals><Growth><Heart Vascular><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Human><Human Milk><Human Mother's Milk><Individuals from minority><Individuals of minority><Infant><Ingestive Behavior><Intervention><Investigators><Ketosis-Resistant Diabetes Mellitus><Lactation><Lactobacillus><Life><Link><Lipids><Literature><Longitudinal Studies><Longitudinal Surveys><Mammary Gland Milk><Maternal Health><Maturity-Onset Diabetes Mellitus><Measures><Metabolic Pathway><Metabolic syndrome><Metagenomics><Milk><Minority Groups><Minority People><Minority Population><Minority individual><Modality><Modern Man><Mother's Milk><Mothers><NIDDM><NIH><National Institutes of Health><Newborn Infant><Newborns><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obesity Epidemic><PFAS><Physical activity><Poly-fluoroalkyl substances><Predisposition><Pregnancy><Preventative measure><Preventive measure><Probiotics><Production><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Sampling><Short-Chain Fatty Acids><Slow-Onset Diabetes Mellitus><Source><Spottings><Stable Diabetes Mellitus><Subgroup><Susceptibility><T2 DM><T2D><T2DM><Testing><Tissue Growth><Transmission><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Unhealthy Diet><United States National Institutes of Health><Volatile Fatty Acids><Weight><Youth><Youth 10-21><adipogenesis><adiposity><adult onset diabetes><adulthood><age 2><age 2 years><aged 2 years><aged two years><ages><aminoacid><bacteria in the gut><bile acid metabolism><bile metabolism><biologic><cardiovascular disorder><child adiposity><child obesity><childhood adiposity><childhood obesity><circulatory system><co-morbid><co-morbidity><cohort><comorbidity><corpulence><critical period><developmental><digestive tract microbiome><drinking water><early life exposure><early-onset obesity><energy balance><enteric microbial community><enteric microbiome><enteric microbiota><environmental chemical><excretion><experiment><experimental research><experimental study><experiments><exposed human population><exposed in utero><fatty liver disease><fecal metabolome><fecal sample><feeding-related behaviors><fetal exposure><gastrointestinal microbial flora><gastrointestinal microbiome><gut bacteria><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiome><gut microbiome of infant><gut microbiota><gut microbiotic><gut microflora><gut-associated microbiome><high risk><human exposure><improved><in utero exposure><infancy><infant gut microbiome><infantile><insight><intestinal biome><intestinal flora><intestinal microbiome><intestinal microbiota><intestinal microflora><intestinal tract microflora><intra-uterine environmental exposure><intrauterine environmental exposure><ketosis resistant diabetes><kids><lack of physical activity><lactating><lactational><later in life><later life><lipid biosynthesis><lipogenesis><long-term study><longitudinal outcome studies><longitudinal research study><mammary cancer detection><mammary screening><maternal milk><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><microbial><multidisciplinary><multiomics><multiple omics><neonate gut microbiome><newborn child><newborn children><newborn gut microbiome><novel><nutrient intake activity><obese children><obesigenic><obesity during childhood><obesity in children><obesity intervention><obesity prevention><obesity risk><obesity therapy><obesity treatment><obesogenic><ontogeny><panomics><pediatric><pediatric obesity><perfluorinated alkyl substances><perfluoroalkyl substances><perfluoroalkylated substances><physical inactivity><polyfluorinated alkyl substances><polyfluoroalkyl substances><poor diet><postnatal><prenatal><prenatal exposure><prenatally exposed><prevent><prevent obesity><preventing><public health priorities><rapid growth><rapid infant weight gain><risk for obesity><risk of obesity><screening><screenings><stool sample><stool specimen><transmission process><two year old><two years of age><type 2 DM><type II DM><type two diabetes><unborn><under served community><underserved community><weights><youngster><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Erik A Willis

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$621,124

FY 2026

Project Title

My weight-their weight: eHealth intervention for managing obesity in child care settings

Grant Number:

5R01DK128174-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Child care centers ─ and their providers ─ are critical partners in public health efforts to address today’s obesity epidemic. Diet and physical activity (PA) habits are formed early, influencing immediate and long-term obesity risk, and both centers and providers play key roles in forming ...

Research Terms

<0-11 years old><5 year old><5 years of age><Address><Adopted><BMI><BMI percentile><BMI z-score><Behavior><Body mass index><Caring><Child><Child Care><Child Youth><Children (0-21)><Cluster randomization trial><Cluster randomized trial><Data><Diet><Dietary intake><Dietary quality><Eating><Effectiveness><Enrollment><Environment><Evaluation><Food Intake><Habits><Health><Health Care Providers><Health Personnel><Health Promotion><Health and Behavior in Children><Health behavior><Healthy Eating><High Prevalence><Instruction><Intervention><Knowledge><Modeling><Nutrition><Obesity><Obesity Epidemic><Organizational Change><Outcome><Outcome Measure><Physical activity><Play><Policies><Prevention program><Process><Provider><Public Health><Puericulture><Quetelet index><RE-AIM><Randomization trial><Randomized><Randomized, Controlled Trials><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Research><Salutogenesis><Specific qualifier value><Specified><Testing><Weight><Weight maintenance regimen><adiposity><age 5><age 5 years><arm><behavior change><care providers><child adiposity><child health care provider><child obesity><childhood adiposity><childhood obesity><clinician behavior><corpulence><diet quality><dietary><diets><e-Health><eHealth><early childhood><electronic health><enroll><evidence base><five year old><five years of age><health care personnel><health care worker><health provider><health related behavior><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><healthy lifestyle><healthy weight><improved><interest><kids><measurable outcome><medical care providers><medical personnel><meeting><meetings><obese children><obesity during childhood><obesity in children><obesity management><obesity prevention><obesity risk><outcome measurement><pediatric care provider><pediatric health care provider><pediatric obesity><pediatric provider><pediatrician><physician behavior><prevent obesity><programs><promoting health><provider behavior><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><recruit><risk for obesity><risk of obesity><secondary analysis><treatment provider><weight control><weight loss intervention><weight loss therapy><weight loss treatment><weight management><weights><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Hollie A Raynor

UNIVERSITY OF TENNESSEE KNOXVILLE, KNOXVILLE, TN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$607,676

FY 2026

Project Title

Effect of time-based energy intake goals on weight loss during obesity treatment.

Grant Number:

5R01DK137752-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/10/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Obesity is a complex disease, and innovative treatments that enhance initial and long-term weight loss are needed. One novel treatment approach uses a biobehavioral framework, focusing on time-based energy intake goals (how energy intake is distributed across the day). Time-...

Research Terms

<21+ years old><Address><Adult><Adult Human><Appetite Regulation><Biological><Body Weight Changes><Body Weight decreased><Caloric Intake><Cell Phone><Cellular Phone><Cellular Telephone><Characteristics><Circadian Rhythms><Cognition Therapy><Cognitive Psychotherapy><Cognitive Therapy><Cognitive treatment><Complex><Consumption><Continuous Glucose Monitor><Diet><Dietary Fats><Disease><Disorder><Eating><Ecological momentary assessment><Energy Intake><Fats><Fatty acid glycerol esters><Food Intake><Goals><Health Benefit><Hunger><Individual><Intake><Intervention><Investigation><Length><Literature><Long-Term Effects><Maintenance><Measures><Mediating><Mediator><Mobile Phones><NIH><National Institutes of Health><Nutrition><Nyctohemeral Rhythm><Obesity><Outcome><Overweight><Participant><Patient Self-Report><Pattern><Physical activity><Randomized><Randomized, Controlled Trials><Self-Report><Sleep><Strategic Planning><Testing><Time><Twenty-Four Hour Rhythm><United States National Institutes of Health><Weight Change><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Work><actigraph><actigraphy><adiposity><adulthood><biobehavior><biobehavioral><biologic><body weight gain><body weight increase><body weight loss><caloric dietary content><circadian><circadian behavioral rhythms><circadian process><circadian rhythmicity><cognitive behavior intervention><cognitive behavior modification><cognitive behavior therapy><cognitive behavioral intervention><cognitive behavioral modification><cognitive behavioral therapy><cognitive behavioral treatment><computer imaging><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><daily biorhythm><dietary><dietary lipid><diets><digital imaging><fall asleep><iPhone><innovate><innovation><innovative><life style intervention><lifestyle intervention><novel><obesity intervention><obesity therapy><obesity treatment><precision nutrition><randomisation><randomization><randomized control trial><randomly assigned><sleep onset><smart phone><smartphone><trial design><vigorous intensity><wt gain><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Leonard H Epstein

STATE UNIVERSITY OF NEW YORK AT BUFFALO, AMHERST, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$589,877

FY 2026

Project Title

Developmental trajectories of reinforcer pathology and childhood obesity

Grant Number:

5R01DK139258-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2025

End Date:

1/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT The percentage of children with obesity increases throughout development. Obesity results from a positive energy balance, which suggests the energy balance gap increases as children age. Reward systems that drive the motivation to eat or be physically active, conceptualized as food and act...

Research Terms

<0-11 years old><12 year old><12 years of age><12-20 years old><16 year old><16 years of age><2 year old><2 years of age><21+ years old><9 year old><9 years of age><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Affect><Age><Behavior><Body fat><Brain><Brain Nervous System><Caloric Intake><Child><Child Youth><Childhood><Children (0-21)><Decision Making><Demographic Factors><Development><Dietary intake><Drops><Eating><Ecologic Monitoring><Ecological Monitoring><Economic Income><Economical Income><Encephalon><Energy Expenditure><Energy Intake><Energy Metabolism><Engineering><Environment><Environmental Monitoring><Equilibrium><Expenditure><Family><Food><Food Intake><Food Supply><Future><Goals><Grant><Home><Income><Individual><Learning><Low income><Measures><Motivation><Nutrition><Obesity><Pathology><Pathway interactions><Pattern><Persons><Physical activity><Play><Prevalence><Process><Psychological reinforcement><Reinforcement><Research><Research Resources><Resources><Rewards><Sedentary behavior><Sedentary life-style><Services><Socioeconomic Factors><Stream><System><Testing><Time><Weight Gain><Weight Increase><Youth><Youth 10-21><adiposity><adolescence (12-20)><adult youth><adulthood><age 12><age 12 years><age 16><age 16 years><age 2><age 2 years><age 9><age 9 years><aged 2 years><aged two years><ages><balance><balance function><behavior phenotype><behavioral economics><behavioral phenotyping><body weight gain><body weight increase><caloric dietary content><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><design><designing><developmental><discount><discounting><early adulthood><early childhood><emerging adult><energy balance><environmental testing><executive control><executive function><food environment><food insecure><food insecurity><food scarcity><high risk><homes><improved><incomes><innovate><innovation><innovative><juvenile><juvenile human><kids><low food security><lower income families><nine year old><nine years of age><novel><obese children><obesigenic><obesity development><obesity during childhood><obesity in children><obesity intervention><obesity risk><obesity therapy><obesity treatment><obesogenic><pathway><pediatric><pediatric obesity><preference><recruit><reinforcer><risk for obesity><risk of obesity><sedentary lifestyle><sixteen year old><sixteen years of age><social factors><social influence><social media><social media platform><social platform><socio-economic factors><theories><twelve year old><twelve years of age><two year old><two years of age><wt gain><young adult><young adult age><young adulthood><youngster><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Takahisa Nakamura

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$584,778

FY 2026

Project Title

RNA silencing machinery in extracellular vesicle-mediated immunometabolic regulation

Grant Number:

5R01DK134646-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2023

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Obesity has solid inflammatory underpinnings, which are risk factors for various chronic inflammatory and metabolic diseases such as type 2 diabetes (T2D). However, how obesity provokes aberrant inflammation remains to be defined. Recent studies indicate that small extracellular vesi...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dale S Bond

HARTFORD HOSPITAL, HARTFORD, CT

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$573,183

FY 2026

Project Title

Using Acceptance and Commitment Therapy to Promote Autonomous Motivation for Increased Physical Activity and Improved Weight Loss Maintenance in Bariatric Surgery Patients: A Randomized Trial

Grant Number:

5R01DK135463-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Nearly one in five U.S. adults have severe obesity (Body Mass Index ≥ 35 kg/m2), which is related to numerous comorbidities and reduced life expectancy. Metabolic and bariatric surgery (MBS) reliably produces substantial, durable weight loss and health improvements for a majority of patients with se...

Research Terms

<21+ years old><Active Follow-up><Adherence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Analgesic Management><BMI><BMI percentile><BMI z-score><Bariatrics><Behavior><Behavioral><Body Weight decreased><Body mass index><COVID-19><CV-19><Clinical><Complication><Coronavirus Infectious Disease 2019><Data><Devices><Dietary intake><E-Mail><Education><Educational aspects><Educational workshop><Electronic Mail><Email><Emotions><Feedback><Future><Goals><Guidelines><Health><Health Promotion><Health behavior><Health behavior change><Hour><Individual><Intervention><Ketosis-Resistant Diabetes Mellitus><Life Expectancy><Link><Maintenance><Maturity-Onset Diabetes Mellitus><Measures><Mediator><Medication Management><Mental Health><Mental Hygiene><Metabolic><Morbid Obesity><Motivation><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Operative Procedures><Operative Surgical Procedures><Outcome><Participant><Patients><Performance><Persons><Pharmacologic Management><Phone><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical activity><Physical therapy><Physiotherapy><Postoperative><Postoperative Period><Prevention><Procedures><Psyche structure><Psychological Health><QOL><Quality of life><Quetelet index><Randomization trial><Randomized><Reporting><Risk><Salutogenesis><Severe obesity><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Surgical><Surgical Interventions><Surgical Procedure><T2 DM><T2D><T2DM><Telephone><Testing><Thinking><Time><Touch><Touch sensation><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Videoconferencing><Weight><Weight Loss><Weight Reduction><Work><Workshop><active followup><adiposity><adult adiposity><adult obesity><adult onset diabetes><adulthood><adults with obesity><bariatric surgery><body weight loss><clinical practice><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><corpulence><effective intervention><effective therapy><effective treatment><electronic communication><exercise intervention><experience><extreme obesity><follow up><follow-up><followed up><followup><gastric banding><gastric bypass surgery><health related behavior><implantable gastric stimulation banding><improved><intervention design><ketosis resistant diabetes><maturity onset diabetes><medication therapy management><mental><obesity intervention><obesity management><obesity surgery><obesity therapy><obesity treatment><physical activity intervention><physical conditioning><physical health><physical impairment><pilot test><prevent><preventing><primary outcome><promoting health><psychosocial><randomisation><randomization><randomized trial><randomly assigned><secondary outcome><stomach stapling><success><surgery><tactile sensation><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><theories><therapy design><thoughts><treatment design><treatment effect><type 2 DM><type II DM><type two diabetes><video conferencing><vigorous intensity><weight loss surgery><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JASON LILLIS

HARTFORD HOSPITAL, HARTFORD, CT

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$573,183

FY 2026

Project Title

Using Acceptance and Commitment Therapy to Promote Autonomous Motivation for Increased Physical Activity and Improved Weight Loss Maintenance in Bariatric Surgery Patients: A Randomized Trial

Grant Number:

5R01DK135463-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Nearly one in five U.S. adults have severe obesity (Body Mass Index ≥ 35 kg/m2), which is related to numerous comorbidities and reduced life expectancy. Metabolic and bariatric surgery (MBS) reliably produces substantial, durable weight loss and health improvements for a majority of patients with se...

Research Terms

<21+ years old><Active Follow-up><Adherence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Analgesic Management><BMI><BMI percentile><BMI z-score><Bariatrics><Behavior><Behavioral><Body Weight decreased><Body mass index><COVID-19><CV-19><Clinical><Complication><Coronavirus Infectious Disease 2019><Data><Devices><Dietary intake><E-Mail><Education><Educational aspects><Educational workshop><Electronic Mail><Email><Emotions><Feedback><Future><Goals><Guidelines><Health><Health Promotion><Health behavior><Health behavior change><Hour><Individual><Intervention><Ketosis-Resistant Diabetes Mellitus><Life Expectancy><Link><Maintenance><Maturity-Onset Diabetes Mellitus><Measures><Mediator><Medication Management><Mental Health><Mental Hygiene><Metabolic><Morbid Obesity><Motivation><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Operative Procedures><Operative Surgical Procedures><Outcome><Participant><Patients><Performance><Persons><Pharmacologic Management><Phone><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical activity><Physical therapy><Physiotherapy><Postoperative><Postoperative Period><Prevention><Procedures><Psyche structure><Psychological Health><QOL><Quality of life><Quetelet index><Randomization trial><Randomized><Reporting><Risk><Salutogenesis><Severe obesity><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Surgical><Surgical Interventions><Surgical Procedure><T2 DM><T2D><T2DM><Telephone><Testing><Thinking><Time><Touch><Touch sensation><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Videoconferencing><Weight><Weight Loss><Weight Reduction><Work><Workshop><active followup><adiposity><adult adiposity><adult obesity><adult onset diabetes><adulthood><adults with obesity><bariatric surgery><body weight loss><clinical practice><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><corpulence><effective intervention><effective therapy><effective treatment><electronic communication><exercise intervention><experience><extreme obesity><follow up><follow-up><followed up><followup><gastric banding><gastric bypass surgery><health related behavior><implantable gastric stimulation banding><improved><intervention design><ketosis resistant diabetes><maturity onset diabetes><medication therapy management><mental><obesity intervention><obesity management><obesity surgery><obesity therapy><obesity treatment><physical activity intervention><physical conditioning><physical health><physical impairment><pilot test><prevent><preventing><primary outcome><promoting health><psychosocial><randomisation><randomization><randomized trial><randomly assigned><secondary outcome><stomach stapling><success><surgery><tactile sensation><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><theories><therapy design><thoughts><treatment design><treatment effect><type 2 DM><type II DM><type two diabetes><video conferencing><vigorous intensity><weight loss surgery><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alma D Guerrero

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$569,859

FY 2026

Project Title

A Hybrid Mobile Phone Family Intervention to Prevent Childhood Obesity

Grant Number:

5R01MD016135-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/13/2022

End Date:

10/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Child obesity disproportionately impacts young Latino children. Obesity interventions focusing on 2- to 5- year-olds are critical as excessive weight gain during this period increases the risk of adolescent and adult overweight and has important implications for later health problem...

Research Terms

<0-11 years old><21+ years old><5 year old><5 years of age><Academy><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Age><Agreement><American><Attenuated><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Body Weight Changes><Body mass index><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Care Givers><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caregivers><Cell Phone><Cellular Phone><Cellular Telephone><Child><Child Care><Child Development><Child Health><Child Rearing><Child Youth><Children (0-21)><Clinical Trials><Collaborations><Consumption><Control Groups><County><Curriculum><Data><Dietary Practices><Educational Curriculum><Effectiveness><Effectiveness of Interventions><Family><Family Care Giver><Family Caregiver><Family member><Fathers><Foundations><Guidelines><Health><Health Benefit><Heart Vascular><Home><Household><Hybrids><Infant Care><Infant and Child Development><Intake><Intervention><K-Awards><K-Series Research Career Programs><Language><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Length><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Los Angeles><Low income><Mediating><Mediator><Methods><Mobile Phones><Mothers><NIH><National Institutes of Health><Nutritional><Obesity><Outcome><Parenting><Parenting behavior><Parents><Pattern><Pediatrics><Persons><Physical activity><Play><Preparation><Prevalence><Protocol><Protocols documentation><Public Health><Puericulture><Quetelet index><Randomized><Research Career Program><Research Design><Research Resources><Resources><Risk><Role><Schools><Shapes><Socialization><Special Supplemental Nutrition Program for Women, Infants, and Children><Study Type><Survey Instrument><Surveys><Systems Theory><Television><Time><Travel><United States National Institutes of Health><WIC><WIC program><Weight><Weight Change><Weight Gain><Weight Increase><Woman><Women, Infants and Children><Work><Youth><Youth 10-21><adiposity><adulthood><age 5><age 5 years><ages><arm><assess effectiveness><attenuate><attenuates><baby care><body weight gain><body weight increase><cardiovascular risk><cardiovascular risk factor><care as usual><child adiposity><child obesity><childhood adiposity><childhood obesity><childrearing><circulatory system><community intervention><community level intervention><community setting><community-based intervention><corpulence><cultural values><design><designing><determine effectiveness><dietary><dietary pattern><disparities in race><disparity due to race><disparity in ethnic><early childhood><effectiveness assessment><effectiveness evaluation><ethnic based disparity><ethnic disadvantage><ethnic disparity><ethnic inequality><ethnic inequity><ethnicity disparity><evaluate effectiveness><evidence base><examine effectiveness><excessive weight gain><experience><extreme weight gain><feasibility testing><feeding><five year old><five years of age><grandchild><grandparent><group intervention><health communication><homes><iPhone><improved><inequality due to race><inequity due to race><infant health care><intervention effect><juvenile><juvenile human><kids><lesson plans><life course><mHealth therapeutic><mHealth therapy><mHealth treatment><mhealth interventions><mobile health intervention><mobile health therapeutic><mobile health therapy><mobile health treatment><newborn care><nutritious><obese children><obesigenic><obesity during childhood><obesity in children><obesity intervention><obesity risk><obesity therapy><obesity treatment><obesogenic><overweight adults><overweight child><overweight childhood><parent><pediatric obesity><post intervention><preparations><prevent><preventing><primary outcome><prospective><race based disparity><race based inequality><race based inequity><race disparity><race related disparity><race related inequality><race related inequity><racial disparity><racial inequality><racial inequity><racially unequal><randomisation><randomization><randomly assigned><recruit><risk for obesity><risk of obesity><role model><scale up><secondary outcome><serious weight gain><severe weight gain><skills><smart phone><smartphone><social influence><social role><study design><sweetened beverage><theories><treatment as usual><treatment site><usual care><weights><wt gain><youngster><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dan Winer

BUCK INSTITUTE FOR RESEARCH ON AGING, NOVATO, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$566,346

FY 2026

Project Title

The B Cell Insulin Receptor in Health and in Insulin Resistance

Grant Number:

5R01DK128435-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2021

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY / ABSTRACT Obesity is a major global health concern. When people become obese, the body fails to respond well to insulin, called insulin resistance. This process can lead to high blood sugar triggering type 2 diabetes, though the underlying causes are poorly understood. We have shown...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><7S Gamma Globulin><Ab response><Activities of Daily Living><Activities of everyday life><Acute><Adipose tissue><Adjuvant><Adult-Onset Diabetes Mellitus><Aging><Antibodies><Antibody Formation><Antibody Production><Automobile Driving><Autoregulation><B-Cell Activation><B-Cells><B-Lymphocytes><B-cell><Behavior><Beta Cell><Binding><Blood Glucose><Blood Sugar><Body Tissues><Brain><Brain Nervous System><COVID-19><COVID-19 related risk><COVID-19 risk><COVID-19 risk factor><COVID-19 virus><COVID19 virus><CV-19><Cell Body><Cell Communication and Signaling><Cell Function><Cell Nucleus><Cell Physiology><Cell Process><Cell Signaling><Cell Survival><Cell Viability><Cells><Cellular Function><Cellular Metabolic Process><Cellular Physiology><Cellular Process><Cellular biology><Chronic><CoV-2><CoV2><Communication><Coronaviridae><Coronavirus><Coronavirus Infectious Disease 2019><D-Glucose><Development><Dextrose><Diabetes Mellitus><Disease><Disorder><Docking><Dysfunction><Encephalon><Environment><Fats><Fatty Tissue><Fatty acid glycerol esters><Frequencies><Functional disorder><GEM model><GEMM model><Gene Transcription><Genes><Genetic Transcription><Genetically Engineered Mouse><Glucose><Grippe><Health><High Fat Diet><Homeostasis><Human><Humulin R><Hyperinsulinemia><Hyperinsulinism><IgG><Immune><Immune Targeting><Immune system><Immunes><Immunity><Immunochemical Immunologic><Immunoglobulin G><Immunologic><Immunological><Immunologically><Immunologics><Immunology><Immunomodulation><Infection><Inflammation><Inflammatory><Inflammatory Response><Influenza><Insulin><Insulin Cell><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin Resistance><Insulin Secreting Cell><Insulin Signaling Pathway><Insulin homeostasis><Insulin-Dependent Tyrosine Protein Kinase><Intermediary Metabolism><Intracellular Communication and Signaling><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out Mice><Knockout Mice><Knowledge><Length of Life><Link><Lipids><Liver><Longevity><Lung><Lung Respiratory System><Lung infections><Maps><Maturity-Onset Diabetes Mellitus><Metabolic><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modern Man><Molecular Interaction><Murine><Mus><Muscle><Muscle Tissue><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nuclear Translocation><Nucleus><Null Mouse><Obese Mice><Obesity><Organism><Orthocoronavirinae><Pathogenicity><Pathway interactions><Pattern><Persons><Physiological Homeostasis><Physiopathology><Play><Process><Production><Proliferating><Proteins><RNA Expression><Receptor Protein><Receptor Signaling><Regular Insulin><Reporting><Research Proposals><Resistance><Risk Factors><Role><SARS><SARS corona virus 2><SARS coronavirus disease><SARS-CO-V2><SARS-COVID-2><SARS-CoV disease><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV disease><Severe Acute Respiratory Syndrome coronavirus disease><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Site><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Subcellular Process><T-Cells><T-Lymphocyte><T2 DM><T2D><T2DM><TLR protein><Time><Tissues><Toll-Like Receptor Family Gene><Toll-like receptors><Transcription><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Viral><Viral Diseases><Virus><Virus Diseases><Visceral><Work><Wuhan coronavirus><activated B cells><adipose><adiposity><adult onset diabetes><antibody biosynthesis><biological signal transduction><cell biology><cell metabolism><cellular metabaolism><corona virus><coronavirus disease 2019><coronavirus disease 2019 risk><coronavirus disease 2019 risk factor><coronavirus disease 2019 virus><coronavirus disease-19><coronavirus disease-19 virus><coronavirus infectious disease-19><corpulence><current pandemic><cytokine><daily living function><daily living functionality><death risk><developmental><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><driving><experiment><experimental research><experimental study><experiments><fighting><flu infection><flu virus infection><functional ability><functional capacity><genetically engineered mouse model><genetically engineered murine model><global health><hCoV19><hepatic body system><hepatic organ system><high risk><immune modulation><immune regulation><immunoglobulin biosynthesis><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><improved><infected with flu><infected with flu virus><infected with influenza><infected with influenza virus><influenza infection><influenza virus infection><insight><insulin balance><insulin control><insulin resistant><insulin signaling><insulin tolerance><ketosis resistant diabetes><living system><maturity onset diabetes><mortality risk><mouse model><murine model><muscular><nCoV2><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><ob/ob mouse><obesity-promoting diet><obesogenic Western-style diet><obesogenic diet><obesogenic high fat diet><obesogenic western diet><pathophysiology><pathway><present pandemic><pro-obesity diet><pulmonary infections><receptor><resistant><response><risk associated with COVID-19><risk factor associated with COVID-19><risk factor related to COVID-19><risk related to COVID-19><social role><thymus derived lymphocyte><type 2 DM><type II DM><type two diabetes><viral infection><virus infection><virus-induced disease><white adipose tissue><yellow adipose tissue><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Maribel Rios

TUFTS UNIVERSITY BOSTON, BOSTON, MA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$561,761

FY 2026

Project Title

Alpha2/delta1- thrombospondin-3 signaling in the central control of metabolic function

Grant Number:

5R01DK138586-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/20/2024

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Brain-derived neurotrophic factor (BDNF) and its receptor TrkB play essential roles in the central regulation of energy and glucose homeostasis. BDNF signaling greatly influences many aspects of neuronal function, including survival, differentiation and synaptic plasticity and transm...

Research Terms

<21+ years old><3-isobutyl GABA><Adult><Adult Human><Affect><Agreement><Analgesic Agents><Analgesic Drugs><Analgesic Preparation><Analgesics><Animals><Anodynes><Anti-epileptic><Antinociceptive Agents><Antinociceptive Drugs><Astrocytes><Astrocytus><Astroglia><Autoregulation><BDNF><BDNF Receptor><BDNF/NT-3 Growth Factors Receptor><Behavior><Binding><Body Weight><Brain><Brain Nervous System><Brain region><Brain-Derived Neurotrophic Factor><Brain-Derived Neurotrophic Factor Receptor><CD36 Antigens><CD36 Fatty Acid Transporter><Calcium><Calcium Channel><Calcium Channel Antagonist Receptor><Calcium Channel Blocker Receptors><Calcium Ion Channels><Cardiovascular Diseases><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell surface><Cells><Clinical><D-Glucose><Data><Deposit><Deposition><Dextrose><Diabetes Mellitus><Diet><Disease><Disorder><Drugs><Dyslipidemias><Eating><Electrophysiology><Electrophysiology (science)><Encephalon><Energy Expenditure><Energy Metabolism><Epidemic><Equilibrium><Excitatory Synapse><Exhibits><Fasting><Fats><Fatty Liver><Fatty acid glycerol esters><Fiber><Food Intake><GP145-TRKB><GPIV Platelet Glycoprotein><Genetic><Glucose><Glucose Intolerance><Health><Hepatic><High Fat Diet><Homeostasis><Human><Hyperphagia><Hypothalamic structure><Hypothalamus><Individual><Insulin Resistance><Intracellular Communication and Signaling><Investigation><Link><Lipids><Liver><Liver Steatosis><Maps><Measures><Mediating><Medication><Metabolic><Metabolic Control><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Mice><Mice Mammals><Modeling><Modern Man><Molecular Interaction><Monitor><Morbid Obesity><Murine><Mus><NTRK2 Receptor><Nerve Cells><Nerve Unit><Neural Cell><Neural Transmission><Neurocyte><Neurons><Neurontin><Neurophysiology / Electrophysiology><Neurotrophic Tyrosine Kinase Receptor Type 2><Obesity><Output><Overeating><Overweight><Pathologic><Pathway interactions><Pharmaceutical Preparations><Photometry><Physiological Homeostasis><Physiology><Play><Population><Predisposition><Receptor Protein><Regulation><Risk Factors><Rodent><Rodentia><Rodents Mammals><Role><Severe obesity><Signal Transduction><Signal Transduction Systems><Signaling><Susceptibility><Synapses><Synaptic><Synaptic Transmission><Synaptic plasticity><TRKB Tyrosine Kinase><TSP-3><TSP3><Testing><Thesaurismosis><Thrombospondin Receptors><Thrombospondins><United States><VDCC><Variant><Variation><Viral><Voltage-Dependent Calcium Channels><adiposity><adulthood><anti-epileptic agents><anti-epileptic drugs><astrocytic glia><balance><balance function><biological signal transduction><blood glucose regulation><cardiovascular disorder><corpulence><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><dietary><diets><drug/agent><electrophysiological><energy balance><extreme obesity><fasted><fasts><fat metabolism><feeding><gabapentin><gain of function><glucose control><glucose homeostasis><glucose metabolism><glucose regulation><glycemic control><hepatic body system><hepatic organ system><hepatic steatosis><hepatosteatosis><hypothalamic><improved><in vivo><insulin resistant><insulin tolerance><knock-down><knockdown><lipid metabolism><male><medical complication><metabolism disorder><mutant><neuronal><neuronal survival><neurotransmitter release><neurotrophic factor><neurotrophin><neutrophin><novel><obesigenic><obesity intervention><obesity therapy><obesity treatment><obesogenic><pain killer><pain medication><pain reliever><painkiller><pathway><polyphagia><pregabalin><prevent><preventing><receptor><response><social role><synapse><synapse formation><synaptogenesis><thrombospondin 3><trkB Receptor><trkB(gp145) Protein><voltage><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nicholas Broskey

EAST CAROLINA UNIVERSITY, GREENVILLE, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$552,661

FY 2026

Project Title

Effect of Maternal Exercise in Women with Obesity on Offspring Mesenchymal Stem Cell Metabolism

Grant Number:

5R01DK137945-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/9/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Obesity in pregnancy increases the risk for excessive adiposity in offspring, which tracks into adulthood and can perpetuate across generations. Our preliminary data and published studies indicate that exercise initiated during pregnancy in sedentary women with obesity lowers infant ...

Research Terms

<(hydroxymethylglutaryl-CoA reductase (NADPH)) kinase><21+ years old><5 year old><5 years of age><5'-AMP-activated protein kinase><ACOG><AMP-activated kinase><AMP-activated protein kinase><AMPK enzyme><Adipocytes><Adipose Cell><Adult><Adult Human><Adverse effects><Aerobic Activity><Aerobic Exercise><Aerobic Training><Aerobic fitness><Affect><Age Months><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><Ancillary Study><BMI><BMI percentile><BMI z-score><Basal Metabolism><Basal metabolic rate><Beta Cell><Bioenergetics><Blood><Blood Reticuloendothelial System><Body Composition><Body Tissues><Body fat><Body mass index><Candidate Disease Gene><Candidate Gene><Cellular Metabolic Process><D-Glucose><DEXA><DXA><Data><Deposit><Deposition><Dextrose><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Energy Expenditure><Energy Metabolism><Enrollment><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exercise><Exposure to><Fat Cells><Fats><Fatty acid glycerol esters><GSK-3beta><GSK-3β><Generations><Genes><Gestation><Glucose><HMG CoA reductase (NADPH) kinase><HMG CoA reductase kinase><HMG coenzyme A reductase (NADPH) kinase><Health><Human><Humulin R><Indirect Calorimetry><Infant><Infant Health><Insulin><Insulin Cell><Insulin Secreting Cell><Intermediary Metabolism><Investigators><Life><Lipids><Lipocytes><Long-term prospective studies><Mature Lipocyte><Mature fat cell><Measures><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Mesoderm Cell><Mesodermal Cell><Metabolic><Metabolic Processes><Metabolism><Mitochondria><Modeling><Modern Man><Mothers><Muscle Cells><Myocytes><Novolin R><Obesity><Outcome><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><Parents><Pathway interactions><Phenotype><Pregnancy><Pregnant Women><Production><Proteins><Publishing><Quetelet index><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Recommendation><Regular Insulin><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Respiration Calorimetry><Rest><Risk><Role><Testing><Tissues><Translating><Triacylglycerol><Triglycerides><Umbilical Cord><Umbilical cord structure><Weight><Woman><Work><adipogenesis><adiposity><adulthood><adverse consequence><adverse outcome><age 5><age 5 years><candidate identification><care as usual><cell metabolism><cell type><cellular metabaolism><child adiposity><child obesity><childhood adiposity><childhood obesity><corpulence><enroll><epigenetically><exercise modalities><expectant mother><expectant women><expecting mother><expecting women><fetal><five year old><five years of age><glycogen synthase kinase 3 beta><glycogen synthase kinase 3β><hydroxymethylglutaryl-CoA-reductase kinase><improved><indexing><individuals who are pregnant><insulin sensitivity><life style intervention><lifestyle intervention><lipid biosynthesis><lipogenesis><longitudinal, prospective study><maternal adiposity><maternal obesity><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><metabolic profile><metabolism measurement><metabolomics><metabonomics><methylation pattern><mitochondrial><mode of exercise><multiomics><multiple omics><myogenesis><obese children><obesity during childhood><obesity during pregnancy><obesity in children><obesity in pregnancy><obesity risk><offspring><oxidation><panomics><parent><parent grant><pathway><pediatric obesity><people who are pregnant><postnatal><pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><progenitor cell model><progenitor model><randomisation><randomization><randomly assigned><resistance exercise><resistance training><respiratory><resting metabolic rate><risk for obesity><risk of obesity><sedentary><social role><stem and progenitor cell model><stem cell based model><stem cell derived model><stem cell model><those who are pregnant><treatment as usual><usual care><weights><women who are pregnant><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tanja V.E. Kral

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$551,488

FY 2026

Project Title

Role of energy balance behaviors in modifying biobehavioral risk factors for childhood obesity

Grant Number:

5R01DK134371-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity is a multifactorial disease which results from complex interactions among multiple genes, behaviors, and environmental factors. A heightened genetic risk does not always translate to the development of obesity among children, which points to the presence of risk-modifying factors that likely...

Research Terms

<0-11 years old><21+ years old><5 year old><5 years of age><Address><Adult><Adult Human><Appetite><Appetitive Behavior><Area><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Biology><Body fat><Body mass index><Caloric Intake><Calories><Child><Child Rearing><Child Youth><Childhood><Children (0-21)><Chronic Disease><Chronic Illness><Circadian Rhythms><Complex><Consumption><DNA><Deoxyribonucleic Acid><Desire for food><Diet><Dietary intake><Dietary quality><Disease><Disorder><Eating><Eating Behavior><Energy Expenditure><Energy Intake><Energy Metabolism><Environment><Environmental Factor><Environmental Risk Factor><Family><Family Characteristics><Food><Food Intake><Genes><Genetic><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Risk><Genetic Susceptibility><Genetic predisposing factor><Genetic propensity><Genotype><Glean><Goals><Heritability><Household><Individual><Inherited Predisposition><Inherited Susceptibility><Intervention><Knowledge><Learning><Literature><Measures><NIH><National Institutes of Health><Nutrition Research><Nutritional Study><Nyctohemeral Rhythm><Obesity><Outcome><Parenting><Parenting behavior><Parents><Pattern><Phenotype><Physical activity><Prevention><Prospective Studies><Quetelet index><Research><Research Resources><Resources><Rest><Risk><Risk Factors><Role><Sampling><Single Base Polymorphism><Single Nucleotide Polymorphism><Sleep><Socio-economic status><Socioeconomic Status><Strategic Planning><Stress><System><Testing><Time><Translating><Twenty-Four Hour Rhythm><United States><United States National Institutes of Health><Variant><Variation><Weight><Youth><Youth 10-21><adiposity><adolescent minority><adulthood><age 5><age 5 years><behavior phenotype><behavioral phenotyping><biobehavior><biobehavioral><caloric dietary content><calorie><child adiposity><child obesity><childhood adiposity><childhood obesity><childrearing><chronic disorder><circadian process><circadian rhythmicity><corpulence><daily biorhythm><diet quality><diets><disparity in health><early childhood><eating in absence of hunger><energy balance><environmental risk><family influence><feeding><fighting><five year old><five years of age><genetic risk factor><genetic vulnerability><genetically predisposed><health disparity><high risk><inherited factor><kids><minority children><minority youth><obese children><obesity development><obesity during childhood><obesity in children><obesity prevention><obesity risk><parent><pediatric><pediatric minority><pediatric obesity><precision nutrition><prevent obesity><primary outcome><prospective><prospective research study><prospective survey><protective factors><public health relevance><racial diversity><racially diverse><risk for obesity><risk mitigation><risk of obesity><single nucleotide variant><sleep amount><sleep duration><sleep episode><sleep interval><sleep length><sleep period><sleep quantity><sleep time><social role><socio-economic position><socioeconomic position><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><trait><waist circumference><weights><young minority><youngster><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Erin Giles

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$550,649

FY 2026

Project Title

Obesity, body fat distribution, and breast cancer risk: is visceral fat the culprit after menopause?

Grant Number:

5R01CA269726-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT The mechanisms that underlie the emergence of an obesity-associated increased risk in breast cancer after menopause are not fully understood. Increased adipose-derived estrogens certainly contribute to obesity-associated postmenopausal breast cancer, but additional mechanism...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Zobeida Cruz-Monserrate

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$525,748

FY 2026

Project Title

Contributions of the Adipose Tissue to the Development of Pancreatic Cancer

Grant Number:

5R01CA279707-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/8/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Obesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), a cancer that has a dismal 5-year survival rate due to limitations in prevention and treatment. Obesity promotes PDAC tumorigenesis and worsens survival by increasing systemic inflammation, metabolic dysfunction, a...

Research Terms

<92-kDa Gelatinase><92-kDa Type IV Collagenase><Adipocytes><Adipose Cell><Adipose tissue><Anabolism><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Arachidonic Acids><Binding><Blood Plasma><Body Composition><Body Tissues><COX-2 protein><COX2 enzyme><Cancers><Cardiolipins><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell secretion><Cells><Cellular Secretion><Chemoresistance><Clinical><Co-culture><Cocultivation><Coculture><Coculture Techniques><Complex><Cyclo-Oxygenase-2><Data><Development><Early Diagnosis><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Fat Cells><Fatty Acid Metabolism Pathway><Fatty Acids><Fatty Tissue><Future><GEM model><GEMM model><Gelatinase B><Generalized Growth><Genetically Engineered Mouse><Goals><Growth><Health><Immune><Immune infiltrates><Immunes><Inflammation><Inflammatory><Intermediary Metabolism><Intracellular Communication and Signaling><Knowledge><LCN2><LCN2 gene><Leanness><Ligands><Linoleic Acids><Lipid Binding><Lipocalin 2><Lipocytes><MMP-9><MMP-9 Protein><Macrophage Gelatinase><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant neoplasm of pancreas><Matrix Metalloproteinase-9><Mature Lipocyte><Mature fat cell><Measures><Metabolic Pathway><Metabolic Processes><Metabolic dysfunction><Metabolism><Mice><Mice Mammals><Mitochondria><Modeling><Molecular><Molecular Interaction><Monitor><Murine><Mus><NGAL><Neutrophil Gelatinase-Associated Lipocalin><Obesity><Obesity Epidemic><Obesity associated cancer><Obesity related cancer><Oncogenesis><Oncogenic Lipocalin 24P3><Organoids><PBMC><PDA model><PDAC Model><PGH Synthase 2><PGHS2><PHS II><Pancreas Cancer><Pancreas Ductal Adenocarcinoma><Pancreatic Cancer><Pancreatic Ductal Adenocarcinoma><Pathway interactions><Patients><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Process><Prostaglandin G/H Synthase 2><Prostaglandin H2 Synthase 2><Prostaglandin-Endoperoxide Synthase 2><Prostaglandins><Prostanoids><Receptor Protein><Reticuloendothelial System, Serum, Plasma><Risk Factors><Signal Transduction><Signal Transduction Systems><Signaling><Skeletal Muscle><Stromal Cells><Stromal Neoplasm><Stromal Tumor><Supplementation><Survival Rate><Testing><Thinness><Tissue Growth><Tissues><Tumor Promotion><Tumor Tissue><Tumor-Derived><Type V Collagenase><Uterocalin><Voluntary Muscle><Work><adipocytokines><adipokines><adipose><adiposity><biological signal transduction><biosynthesis><cancer microenvironment><cancer progression><chemoresistant><chemotherapy resistance><chemotherapy resistant><corpulence><cyclo-oxygenase II><cyclooxygenase 2><cytokine><developmental><dietary><early detection><fatty acid metabolism><genetically engineered mouse model><genetically engineered murine model><immune cell infiltrate><improved><insight><insulin sensitivity><lipid bound><lipidomics><malignancy><mitochondrial><neoplasm progression><neoplasm/cancer><neoplastic progression><novel><obese individuals><obese people><obese person><obese population><obese subjects><obesity development><ontogeny><pancreas development><pancreatic ductal adenocarcinoma model><pancreatic malignancy><pancreatic stellate cell><pathway><prevent><preventing><prostaglandin H synthase-2><protein complex><receptor><systemic inflammation><systemic inflammatory response><treatment strategy><tumor><tumor microenvironment><tumor progression><tumorigenesis><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph A. Baur

UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, SAN ANTONIO, TX

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$524,931

FY 2026

Project Title

Mechanisms and therapeutic potential of blocking the mitochondrial Mg2+ channel Mrs2 in obesity and NAFLD

Grant Number:

5R01DK135179-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Aberrant hepatic glucose and lipid metabolism is a feature of several prevalent metabolic disorders, including obesity, type 2 diabetes (T2DM) and nonalcoholic fatty liver disease (NAFLD). Increased hepatic glucose production directly contributes to hyperglycemia in patients with T2DM, and ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MADESH MUNISWAMY

UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, SAN ANTONIO, TX

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$524,931

FY 2026

Project Title

Mechanisms and therapeutic potential of blocking the mitochondrial Mg2+ channel Mrs2 in obesity and NAFLD

Grant Number:

5R01DK135179-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Aberrant hepatic glucose and lipid metabolism is a feature of several prevalent metabolic disorders, including obesity, type 2 diabetes (T2DM) and nonalcoholic fatty liver disease (NAFLD). Increased hepatic glucose production directly contributes to hyperglycemia in patients with T2DM, and ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Rodney E Infante

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$516,395

FY 2026

Project Title

LIFR-alpha/JAK/STAT3-dependent Adipose Inflammation Contributes to Obesity-Associated NAFLD - Resubmissi

Grant Number:

5R01DK128166-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Although adipose inflammation is associated with obesity, its role in reprogramming adipocytes and other cells in adipose towards the development of obesity’s metabolic comorbidities including steatosis remain unclear. The complex intracellular (stromal, vascular, immune, and adipocyte) ...

Research Terms

<3'5'-cyclic ester of AMP><3,5 cyclic AMP synthetase><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Adenyl Cyclase><Adenylate Cyclase><Adenylyl Cyclase><Adipocytes><Adipose Cell><Adipose tissue><Affect><Animals><Atlases><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Blood Vessels><Cell Body><Cell Communication and Signaling><Cell Line><Cell Signaling><CellLine><Cells><Cholinergic Differentiation Factor><Complex><Cyclic AMP><Cytokine Signal Transduction><Cytokine Signaling><D-Factor><Data><Dependence><Development><Diet><Equilibrium><Family><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Genetic><Genetic Models><HPGF><Hepatic><Hepatocyte-Stimulating Factor><High Fat Diet><Hybridoma Growth Factor><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Immune><Immune signaling><Immunes><Inflammation><Inflammatory><Interleukin-6><Intracellular Communication and Signaling><KO mice><Knock-out Mice><Knockout Mice><LIF><LIF gene><LIF receptor><LIF-R><LIF-binding protein><LIFR><LIFR gene><Lipid Mobilization><Lipocytes><Lipolysis><Liver><MGI-2><Mature Lipocyte><Mature fat cell><Mediating><Mediator><Messenger RNA><Metabolic><Mice><Mice Mammals><Modeling><Molecular><Murine><Mus><Myeloid Differentiation-Inducing Protein><NAFLD><Null Mouse><Obesity><Pathway interactions><Phenotype><Phosphorylation><Plasmacytoma Growth Factor><Protein Phosphorylation><RNA Seq><RNA sequencing><RNAseq><Receptor Protein><Recombinants><Regulation><Resolution><Role><STAT3><STAT3 gene><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Steatohepatitis><Strains Cell Lines><Techniques><Triacylglycerol><Triglycerides><Wild Type Mouse><adenosine 3'5' monophosphate><adipocytokines><adipokines><adipose><adiposity><balance><balance function><biological signal transduction><cAMP><cell type><co-morbid><co-morbidity><comorbidity><compare to control><comparison control><corpulence><counterregulation><cultured cell line><cytokine><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><global gene expression><global transcription profile><hepatic body system><hepatic organ system><in vitro Assay><inhibitor><interferon beta 2><leukemia inhibitor factor><leukemia inhibitory factor><leukemia inhibitory factor receptor><mRNA><mouse model><murine model><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><obesity development><pathway><programs><receptor><resolutions><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><transcriptome><transcriptome sequencing><transcriptomic sequencing><vascular><white adipose tissue><wildtype mouse><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Puneeth Iyengar

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$516,395

FY 2026

Project Title

LIFR-alpha/JAK/STAT3-dependent Adipose Inflammation Contributes to Obesity-Associated NAFLD - Resubmissi

Grant Number:

5R01DK128166-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Although adipose inflammation is associated with obesity, its role in reprogramming adipocytes and other cells in adipose towards the development of obesity’s metabolic comorbidities including steatosis remain unclear. The complex intracellular (stromal, vascular, immune, and adipocyte) ...

Research Terms

<3'5'-cyclic ester of AMP><3,5 cyclic AMP synthetase><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Adenyl Cyclase><Adenylate Cyclase><Adenylyl Cyclase><Adipocytes><Adipose Cell><Adipose tissue><Affect><Animals><Atlases><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Blood Vessels><Cell Body><Cell Communication and Signaling><Cell Line><Cell Signaling><CellLine><Cells><Cholinergic Differentiation Factor><Complex><Cyclic AMP><Cytokine Signal Transduction><Cytokine Signaling><D-Factor><Data><Dependence><Development><Diet><Equilibrium><Family><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Genetic><Genetic Models><HPGF><Hepatic><Hepatocyte-Stimulating Factor><High Fat Diet><Hybridoma Growth Factor><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Immune><Immune signaling><Immunes><Inflammation><Inflammatory><Interleukin-6><Intracellular Communication and Signaling><KO mice><Knock-out Mice><Knockout Mice><LIF><LIF gene><LIF receptor><LIF-R><LIF-binding protein><LIFR><LIFR gene><Lipid Mobilization><Lipocytes><Lipolysis><Liver><MGI-2><Mature Lipocyte><Mature fat cell><Mediating><Mediator><Messenger RNA><Metabolic><Mice><Mice Mammals><Modeling><Molecular><Murine><Mus><Myeloid Differentiation-Inducing Protein><NAFLD><Null Mouse><Obesity><Pathway interactions><Phenotype><Phosphorylation><Plasmacytoma Growth Factor><Protein Phosphorylation><RNA Seq><RNA sequencing><RNAseq><Receptor Protein><Recombinants><Regulation><Resolution><Role><STAT3><STAT3 gene><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Steatohepatitis><Strains Cell Lines><Techniques><Triacylglycerol><Triglycerides><Wild Type Mouse><adenosine 3'5' monophosphate><adipocytokines><adipokines><adipose><adiposity><balance><balance function><biological signal transduction><cAMP><cell type><co-morbid><co-morbidity><comorbidity><compare to control><comparison control><corpulence><counterregulation><cultured cell line><cytokine><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><global gene expression><global transcription profile><hepatic body system><hepatic organ system><in vitro Assay><inhibitor><interferon beta 2><leukemia inhibitor factor><leukemia inhibitory factor><leukemia inhibitory factor receptor><mRNA><mouse model><murine model><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><obesity development><pathway><programs><receptor><resolutions><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><transcriptome><transcriptome sequencing><transcriptomic sequencing><vascular><white adipose tissue><wildtype mouse><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Anutosh Chakraborty

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$514,813

FY 2026

Project Title

Determining hepatocyte-specific mechanisms by which Ube4A regulates NAFLD/NASH

Grant Number:

7R01DK132162-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project summary Obesity is a major risk factor for NAFLD/NASH. In obesity, energy accumulation causes metabolic dysfunction and endoplasmic reticulum (ER) and oxidative stress, leading to tissue inflammation and injury, which are hallmarks of NASH. The DNA damage response and unfolded protein respon...

Research Terms

<2-Methyl-1,4-naphthalenedione><2-Methyl-1,4-naphthoquinone><2-Methylnaphthoquinone><APF-1><ATP-Dependent Proteolysis Factor 1><Adeno-Associated Viruses><Adipocytes><Adipose Cell><Assay><Autoregulation><Bioassay><Biological Assay><Body Tissues><Cancers><Caspase><Caspase Gene><Cell Body><Cell Death><Cell Death Induction><Cell Survival><Cell Viability><Cell-Death Protease><Cells><Cellular Metabolic Process><Cellular Stress><Cellular Stress Response><Cessation of life><Chiro-Inositol><Cirrhosis><Cysteine Endopeptidases><Cysteine Protease><Cysteine Proteinases><DNA Damage><DNA Injury><Death><Dependoparvovirus><Dependovirus><Development><Diphosphates><Disease><Disorder><Drug Therapy><E3 Ligase><E3 Ubiquitin Ligase><ER stress><Economics><Endoplasmic Reticulum><Energy Expenditure><Energy Metabolism><Enzyme Gene><Enzymes><Ergastoplasm><Fat Cells><Fatty Acids><Fatty Liver><Genome><Glycolysis><Goals><HMG-20><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><Hexadecanoates><High Mobility Protein 20><Homeostasis><Human><Hyperinsulinemia><Hyperinsulinism><ICE-like protease><Impairment><In Vitro><Inflammation><Injury><Injury to Liver><Inositol><Insulin Resistance><Intermediary Metabolism><KO mice><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Link><Lipocytes><Liver><Liver Cells><Liver Steatosis><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Mediating><Mediator><Menadione><Mesoinositol><Metabolic><Metabolic Processes><Metabolic Protein Degradation><Metabolic dysfunction><Metabolism><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Mutate><NAFLD><NASH><Nuclear><Null Mouse><Obese Mice><Obesity><Oxidative Stress><Oxidative Stress Induction><Oxygen Consumption><Palmitates><Pathway interactions><Patients><Pharmacological Treatment><Pharmacotherapy><Physiological Homeostasis><Process><Production><Protein Turnover><Proteins><Proteome><Public Health><Pyrophosphates><RNA Seq><RNA sequencing><RNAseq><Regulation><Regulatory Protein Degradation><Research><Risk Factors><Role><Site><Stress><System><Testing><Therapeutic><Tissues><Tunicamycin><Ubiquitilation><Ubiquitin><Ubiquitin Protein Ligase><Ubiquitin-Protein Ligase Complexes><Ubiquitin-Protein Ligase E3><Ubiquitination><Ubiquitinoylation><Vitamin K 3><Vitamin K3><adeno associated virus group><adenoviral mediated><adenovirus-mediated><adiposity><cell metabolism><cell stress><cellular metabaolism><cirrhotic><corpulence><cystein protease><cystein proteinase><cysteine endopeptidase><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><drug intervention><drug treatment><economic><endoplasmic reticulum stress><glucose uptake><hepatic body system><hepatic damage><hepatic injury><hepatic organ system><hepatic steatosis><hepatosteatosis><in vivo><inhibitor><injuries><innovate><innovation><innovative><insulin resistant><insulin sensitivity><insulin signaling><insulin tolerance><liver damage><liver injury><malignancy><mutant><necrocytosis><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutics><new therapy><new therapy approaches><new treatment approach><new treatment strategy><next generation therapeutics><non-alcohol fatty liver disease><non-alcohol induced steatohepatitis><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic fatty liver disease><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutics><novel therapy><novel therapy approach><ob/ob mouse><obese individuals><obese people><obese person><obese population><obese subjects><obesigenic><obesogenic><overexpress><overexpression><pathway><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><prevent><preventing><protein degradation><protein homeostasis><proteostasis><response><social><social role><stressor><tool><transcriptome sequencing><transcriptomic sequencing><ubiquination><ubiquitin conjugation><ubiquitin-protein ligase><uptake><western diet><western-style diet><western-type diet>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jeffrey David Roizen

CHILDREN'S HOSP OF PHILADELPHIA, PHILADELPHIA, PA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$509,945

FY 2026

Project Title

Vitamin D control of calorie allocation to muscle

Grant Number:

5R01DK134717-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Obesity causes the greatest proportional risk for diabetes, heart disease, and cancer and is resistant to current treatments despite being a focus of intense research. Obesity occurs because the body stores surplus calories as fat, which in turn drives the health risks assoc...

Research Terms

<1,25-Dihydroxycholecalciferol Receptors><1,25-Dihydroxyvitamin D 3 Receptors><1,25-Dihydroxyvitamin D3 Receptors><25-Hydroxycholecalciferol><25-Hydroxyvitamin D 3><25-Hydroxyvitamin D3><25-hydroxy-D3><Area><Assay><Binding><Binding Sites><Bioassay><Biological Assay><Blood Serum><Body Weight decreased><Calcidiol><Calcifediol><Calcitriol><Calcitriol Receptors><Calcium><Caloric Restriction><Calories><Cancers><Cardiac Diseases><Cardiac Disorders><Cell Communication and Signaling><Cell Culture Techniques><Cell Signaling><Cholecalciferol Receptors><Combining Site><DNA Binding><DNA Binding Interaction><DNA bound><Data><Dedications><Development><Diabetes Mellitus><Disease><Disorder><Dose><Elements><Enzyme Gene><Enzymes><Exercise><Fats><Fatty acid glycerol esters><GEM model><GEMM model><Gene Expression><Gene Transcription><Generations><Genes><Genetic Transcription><Genetically Engineered Mouse><Goals><Grip strength><Hand Strength><Health><Heart Diseases><Hydroxylases><Hydroxylation><In Vitro><Incidence><Intermediary Metabolism><Intracellular Communication and Signaling><Investigators><KO mice><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Leanness><Length of Life><Longevity><Malignant Neoplasms><Malignant Tumor><Maps><Measures><Mediating><Metabolic Processes><Metabolism><Mice><Mice Mammals><Mitochondria><Mixed Function Oxidases><Mixed Function Oxygenases><Modeling><Molecular Interaction><Monooxygenases><Murine><Mus><Muscle><Muscle Mitochondria><Muscle Tissue><Muscle function><Null Mouse><Obese Mice><Obesity><Output><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><Pathway interactions><Pennsylvania><QOL><Qualifying><Quality of life><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Reactive Site><Receptor Signaling><Research><Research Personnel><Researchers><Resistance><Risk><Role><Running><Sarcosomes><Serum><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Testing><Therapeutic><Thinness><Time><Transcription><Transcriptional Control><Transcriptional Regulation><Universities><VIT D><Vitamin D><Vitamin D 3 Receptors><Vitamin D Receptors><Vitamin D Response Element><Vitamin D3 Receptor><Weight Loss><Weight Reduction><Work><adiposity><biological signal transduction><body weight loss><calorie><calorie restriction><career><cell culture><cell cultures><corpulence><daily functioning><developmental><diabetes><diabetes risk><dietary><genetically engineered mouse model><genetically engineered murine model><genome scale><genome wide analysis><genome wide studies><genome-wide><genome-wide analysis><genome-wide identification><genomewide><global gene expression><global transcription profile><heart disorder><improved><in vivo><malignancy><mitochondrial><mouse model><murine model><muscle bulk><muscle form><muscle mass><muscle physiology><muscular><neoplasm/cancer><new drug target><new druggable target><new pharmacotherapy target><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutic target><new therapy approaches><new therapy target><new treatment approach><new treatment strategy><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutic target><novel therapy approach><novel therapy target><ob/ob mouse><obesity intervention><obesity risk><obesity therapy><obesity treatment><pathway><prevent><preventing><professor><receptor binding><receptor bound><resistant><response><risk for obesity><risk of obesity><side effect><social role><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><tenure process><tenure track><transcriptome><transcriptome sequencing><transcriptomic sequencing><treadmill><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alexxai V Kravitz

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$502,361

FY 2026

Project Title

Accumbal adaptations that contribute to weight regain after weight loss

Grant Number:

5R01DK138131-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract Losing weight can be life saving for people with obesity. However, among patients that do lose significant weight, most have trouble keeping the weight off. People with obesity that lose weight experience physiological, neural, and behavioral changes that drive weight regain...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Laura J. den Hartigh

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$485,375

FY 2026

Project Title

Distinct functions of adipocyte-derived FGF21 in obesity

Grant Number:

5R01DK135756-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Title: Distinct functions of adipocyte-derived FGF21 in obesity Summary Obesity is rapidly reaching epidemic proportions, with an urgent need for novel strategies for weight loss. Fibroblast growth factor 21 (FGF21) is a hormone derived from the liver and adipose tissue that plays a beneficial role ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gina Marie Leinninger

MICHIGAN STATE UNIVERSITY, EAST LANSING, MI

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$484,739

FY 2026

Project Title

Role of Lateral Hypothalamic Neurotensin Neurons in Energy Balance

Grant Number:

5R01DK103808-12

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2014

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Obesity and chronic pain frequently occur together, which is exacerbated by current pain medications that induce further weight gain. Our limited understanding of the common neurobiological factor(s) underlying obesity and pain is a major knowledge gap preventing design of effective ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Anthony W Ferrante

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$484,185

FY 2026

Project Title

IgG and Adipose Pathological Remodeling

Grant Number:

5R01DK134471-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/6/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Obesity is responsible for numerous, highly prevalent comorbidities such as insulin resistance, type 2 diabetes, cardiovascular diseases (CVDs), dyslipidemia, liver diseases, and cancers - all of which are indispensably related to adipose tissue pathologies. Adipose tissue is vital f...

Research Terms

<7S Gamma Globulin><Address><Adipocyte precursor><Adipocytes><Adipose Cell><Adipose tissue><Adult-Onset Diabetes Mellitus><Aging><Antibodies><Antisense Agent><Antisense Oligonucleotides><Automobile Driving><Autoregulation><Biochemical><Body Tissues><Caloric Restriction><Cancers><Cardiovascular Diseases><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic><Data><Dependence><Development><Drug or chemical Tissue Distribution><Dysfunction><Dyslipidemias><Fat Cells><Fat progenitor cell><Fat stem cell><Fatty Tissue><FcRn><FcRn neonatal transfer protein><Fibrosis><Functional disorder><Genes><Half-Life><Health><Hepatic Disorder><High Fat Diet><Homeostasis><Homolog of Drosophila TOLL><Hypertrophy><IgG><Immune><Immune Regulators><Immunes><Immunoglobulin G><Immunologic Factors><Immunological Factors><Immunomodulators><Impairment><Inflammation><Inflammatory><Insulin Resistance><Intermediary Metabolism><Intracellular Communication and Signaling><JV15-2><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Label><Leanness><Ligands><Light><Lipocytes><Liver diseases><LoxP-flanked allele><MADH3><MADH3 gene><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Mediator><Medical><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolic dysfunction><Metabolism><Mice><Mice Mammals><Modeling><Molecular><Mothers Against Decapentaplegic, Drosophila, Homolog of, 3><Murine><Mus><Myeloid Cells><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Null Mouse><Obese Mice><Obesity><PPAR><Pathogenicity Factors><Pathologic><Pathology><Peroxisome Proliferator-Activated Receptors><Phenotype><Photoradiation><Physiological Homeostasis><Physiopathology><Preadipocytes><Precursor to adipocyte><Prevention><Production><Progenitor Cells><Proteins><Recycling><Repression><Role><SMA- and MAD-Related Protein 3><SMAD3><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stromal Cells><T2 DM><T2D><T2DM><TIL4><TLR2><TLR2 gene><TLR2 receptor><TLR4><TLR4 gene><Testing><Therapeutic><Thesaurismosis><Thinness><Tissue Distribution><Tissues><Toll Homologue><Toll-Like Receptor 2><Toll/Interleukin 1 Receptor-Like 4><Toll/Interleukin 1 Receptor-Like 4 Gene><Toll/Interleukin 1 Receptor-Like Protein 4><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Virulence Factors><Weight Gain><Weight Increase><Work><adipocyte progenitors><adipocyte stem cell><adipocyte-derived stem cell><adipogenesis><adipose><adipose derived stem cell><adipose progenitor><adipose stem cell><adipose tissue derived stem cell><adipose tissue stem cells><adiposity><adult onset diabetes><antisense oligo><biological signal transduction><body weight gain><body weight increase><calorie restriction><cardiovascular disorder><co-morbid><co-morbidity><comorbidity><conditional knock-out><conditional knockout><corpulence><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><driving><effective intervention><energy balance><fat cell precursor><fat derived stem cell><floxed><floxed allele><hepatic disease><hepatopathy><immune modulators><immunologic substance><immunological substance><immunomodulatory molecules><immunoregulator><immunoregulatory molecules><improved><in vitro Model><in vivo><insight><insulin resistant><insulin sensitivity><insulin tolerance><ketosis resistant diabetes><lipid biosynthesis><lipogenesis><liver disorder><malignancy><maturity onset diabetes><metabolism disorder><mouse genetics><neonatal Fc receptor><neoplasm/cancer><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><ob/ob mouse><overexpress><overexpression><pathophysiology><prevent><preventing><progenitor><social role><stem cells><toll-like receptor 4><type 2 DM><type II DM><type two diabetes><white adipose tissue><wt gain><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LIANGYOU RUI

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$474,240

FY 2026

Project Title

Role of adipose mRNA modifications in metabolic disease

Grant Number:

5R01DK130111-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Abstract Excessive white adipose tissue (WAT) is a hallmark of obesity and a causal factor for obesity-associated disease. Adipose secretion of adipokines is also dysregulated in obesity, further impairing WAT crosstalk with other tissues. Extensive research has been focused on gene transcriptions a...

Research Terms

<1,2,3-Propanetriol><1,2,3-Trihydroxypropane><1-Phosphatidylinositol 3-Kinase><AAV delivered><AAV delivery><AAV-based delivery><AAV-based viral delivery><AAV-mediated delivery><ACRP30 protein><Adeno-associated-virus-based delivery><Adipocytes><Adipose Cell><Adipose tissue><Adrenergic Agents><Adrenergic Drugs><Adrenergics><Adult-Onset Diabetes Mellitus><Binding><Body Tissues><Brown Adipose Tissue><Brown Fat><Catalytic Core><Catalytic Domain><Catalytic Region><Catalytic Site><Catalytic Subunit><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Complex><Development><Diabetes Mellitus><Dysfunction><EC 2.1.1><Embryo><Embryonic><Endocrine Gland Secretion><Exercise><Fat Cells><Fats><Fatty Liver><Fatty Tissue><Fatty acid glycerol esters><Free Fatty Acids><Functional disorder><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Proteins><Gene Transcription><Generalized Growth><Genetic><Genetic Transcription><Glycerin><Glycerol><Glycerol Monoester Hydrolases><Glycerol-ester acylhydrolase><Growth><Hibernating Gland><High Fat Diet><Hormones><Humulin R><Impairment><Insulin><Insulin Resistance><Intermediary Metabolism><Intracellular Communication and Signaling><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out Mice><Knockout Mice><Life><Life Cycle><Life Cycle Stages><Link><Lipase><Lipocytes><Lipolysis><Liver><Liver Steatosis><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Mediating><Messenger RNA><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Methylation><Methyltransferase><Mice><Mice Mammals><Modeling><Modification><Molecular Interaction><Monoacylglycerol Lipases><Monoglyceride Esterases><Monoglyceride Hydrolase><Monoglyceride Lipases><Murine><Mus><NAFLD><NIDDM><Neonatal Mortality><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Polyadenylated RNA><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nuclear Export><Null Mouse><Obesity><Obesity associated disease><Obesity related disease><Outcome><PI-3 Kinase><PI3-Kinase><PI3CG><PI3KGamma><PI3k><PIK3><PIK3CG><PIK3CG gene><Pathway interactions><Phosphatidylinositol 3-Kinase><Phosphatidylinositol-3-OH Kinase><Phosphoinositide 3-Hydroxykinase><Physiopathology><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Pre-mRNA><Process><Protein Biosynthesis><Protein Family><Protein Gene Products><Protein Modification><Proteins><PtdIns 3-Kinase><RNA><RNA Binding><RNA Expression><RNA Gene Products><RNA Splicing><RNA bound><RNA methylation><RNA, Messenger, Precursors><Reaction><Reader><Regular Insulin><Research><Resistance><Ribonucleic Acid><Ribosomal Peptide Biosynthesis><Ribosomal Protein Biosynthesis><Ribosomal Protein Synthesis><Role><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Splicing><Stable Diabetes Mellitus><Starvation><Sympathetic Nervous System><System><T2 DM><T2D><T2DM><Testing><Therapeutic Hormone><Thesaurismosis><Tissue Expansion><Tissue Growth><Tissues><Transcript><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Translations><Triacylglycerol><Triacylglycerol Hydrolase><Triacylglycerol Lipase><Triacylglycerol acylhydrolase><Tributyrinase><Triglyceridase><Triglyceride Lipase><Triglycerides><Triolean Hydrolase><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Phosphatidylinositol Kinase><Type II Diabetes Mellitus><Type II diabetes><Type III Phosphoinositide 3-Kinase><adeno-associated viral vector delivery><adeno-associated virus delivery><adeno-associated virus mediated delivery><adenovirus mediated delivery><adipocyte complement-related protein 30-kDa><adipocyte, C1q and collagen domain containing protein><adipocytokines><adipokines><adiponectin><adipose><adiposity><adult onset diabetes><analyze gene expression><apM-1 protein><apM1 (adipose-specific) protein><biological signal transduction><cell behavior><cellular behavior><corpulence><death among neonates><death among newborns><death in neonates><death in newborn><delivered with AAV><delivery with AAV><developmental><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><driving force><epitranscriptomics><fatty liver disease><gain of function><gene expression analysis><gene expression assay><glucose metabolism><hepatic body system><hepatic organ system><hepatic steatosis><hepatosteatosis><improved><insulin resistant><insulin signaling><insulin tolerance><ketosis resistant diabetes><life course><mRNA><mRNA Decay><mRNA Precursor><maturity onset diabetes><metabolism disorder><methylase><mortality among neonates><mortality among newborns><mortality in neonates><mortality in newborns><mutant><neonatal death><neonatal demise><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><newborn death><newborn mortality><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><obesigenic><obesity intervention><obesity therapy><obesity treatment><obesogenic><ontogeny><overexpress><overexpression><pathophysiology><pathway><posttranscriptional><protein synthesis><resistant><social role><trafficking><transcriptional profiling><translation><transmethylase><tributyrase><type 2 DM><type II DM><type two diabetes><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Xing Zeng

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$419,453

FY 2026

Project Title

Mechanistic Connection between Interorganellar Communication and Obesity-associated Diseases

Grant Number:

5R01DK135556-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary Obesity is a leading risk factor for type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular diseases. A central driver of pathogenesis in obesity-associated disorders is the insufficient lipid-storing capacity of adipocytes and subsequent lipid deposition in extra-adip...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alexis M. Stranahan

AUGUSTA UNIVERSITY, AUGUSTA, GA

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$397,713

FY 2026

Project Title

Adipose tissue distribution determines microglial regulation of hippocampal plasticity

Grant Number:

5R01DK110586-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2017

End Date:

2/28/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY The ‘apple-shaped’ anatomical pattern that accompanies visceral adiposity increases dementia risk in humans, but the 'pear-shaped' distribution that reflects subcutaneous adiposity does not predict cognitive impairment and may be protective. Several recent studies, including from our...

Research Terms

<4-Hydroxy-Tamoxifen><4-hydroxytamoxifen><4-monohydroxytamoxifen><AD dementia><Abbreviations><Abdominal obesity><Ablation><Adipose tissue><Adult females><Adult women><Age associated cognitive deficit><Age associated cognitive dysfunction><Age related memory decline><Age related memory deficit><Age related memory impairment><Age-associated cognitive decline><Age-related cognitive decline><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Amentia><Ammon Horn><Anatomic Sites><Anatomic structures><Anatomy><Android fat distribution><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Apple><Area><Autocrine Systems><Autoimmune Diseases><B-Cell Differentiation Factor-1><B-Cell Growth Factor-1><B-Cell Growth Factor-I><B-Cell Proliferating Factor><B-Cell Stimulating Factor><B-Cell Stimulating Factor-1><B-Cell Stimulation Factor-1><B-Cell Stimulatory Factor 1 Gene><B-Cell Stimulatory Factor-1><BCDF-1><BCGF><BCGF-1><BCSF 1><BSF-1><BSF-1 Gene><BSF1><BSF1 Gene><Behavioral><Benign senescent forgetfulness><Binetrakin><Blood leukocyte><Body Tissues><Body fat><Brain><Brain Inflammation><Brain Nervous System><CD124 Antigens><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CDw124 Antigen><CNS Nervous System><Cardiovascular Pathology><Cell Body><Cell Communication and Signaling><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cell Signaling><Cells><Central Nervous System><Central obesity><Centripetal obesity><Cerebrospinal Fluid><Cervical Lymph Node><Cervical lymph node group><Chronic><Clinical Research><Clinical Study><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Cornu Ammonis><Cre driver><Cytokine Signal Transduction><Cytokine Signaling><Data><Dementia><Detection><Diabetes Mellitus><Differences between sexes><Differs between sexes><Dissection><Disturbance in cognition><Drug or chemical Tissue Distribution><Dysfunction><Electrophysiology><Electrophysiology (science)><Encephalitis><Encephalon><Epidemic><Exhibits><Experimental Models><Fats><Fatty Tissue><Fatty acid glycerol esters><Feedback><Female><Females in adulthood><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Functional disorder><Glia><Glial Cells><Goals><Health><Height><High Fat Diet><Hippocampus><Homing><Hortega cell><Human><Hypertension><IL-13><IL-4><IL-4 Gene><IL-4 Receptors><IL13><IL4><IL4 Protein><IL4 Receptors><IL4 gene><Image><Immune><Immunes><Immunity><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Impaired cognition><Inflammation><Innate Immunity><Integral Membrane Protein><Interleukin 4 Receptor><Interleukin-13><Interleukin-4><Interleukin-4 Gene><Interleukin-4 Precursor><Interleukin-4 Precursor Gene><Interleukin-4 Receptor Alpha><Intracellular Communication and Signaling><Intrinsic Membrane Protein><Kolliker's reticulum><Leukocytes><Leukocytes Reticuloendothelial System><Light><Link><Lipectomy><Lymphatic cell><Lymphocyte><Lymphocyte Stimulatory Factor 1><Lymphocytic><MCGF-2><Machine Learning><Malus domestica><Maps><Marrow leukocyte><Masculine><Masculinity><Mast Cell Growth Factor-2><Measures><Meningeal><Meninges><Metabolic><Mice><Mice Mammals><Microglia><Modern Man><Morphology><Murine><Mus><Myeloid Cells><Native Immunity><Natural Immunity><Nerve Cells><Nerve Unit><Neural Cell><Neuraxis><Neurocyte><Neuroglia><Neuroglial Cells><Neuroimmune><Neurons><Neurophysiology / Electrophysiology><Non-Specific Immunity><Non-neuronal cell><Nonneuronal cell><Nonspecific Immunity><Obesity><Overnutrition><Pathogenesis><Pathology><Pattern><Pear><Peripheral><Photoradiation><Physiologic><Physiological><Physiopathology><Pilot Projects><Population><Predisposition><Prevalence><Primary Senile Degenerative Dementia><Publishing><Pyrus><Regulation><Reporter><Reporting><Risk><Risk Factors><Role><Route><Sex Differences><Sexual differences><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Structure><Susceptibility><Synapses><Synaptic><T-Cell Growth Factor 2><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><Tamoxifen><Testing><Therapeutic><Tissue Distribution><Tissue Transplantation><Tissues><Toxin><Transmembrane Protein><Transmembrane Protein Gene><Transplantation Surgery><Truncal obesity><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Visceral><Weight><White Blood Cells><White Cell><Woman><Women in adulthood><Women's study><adipose><adiposity><age associated cognitive impairment><age associated memory decline><age associated memory deficit><age related cognitive deficit><age related cognitive dysfunction><age related cognitive impairment><age related memory dysfunction><age-associated memory impairment><age-induced cognitive decline><age-related decline in cognition><age-related decline in cognitive function><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><aging population><aging related cognitive decline><autocrine><autoimmune condition><autoimmune disorder><autoimmunity disease><biological sex><biological signal transduction><cell sorting><cerebral spinal fluid><co-morbid><co-morbidity><cognitive assessment><cognitive dysfunction><cognitive loss><cognitive testing><comorbidity><corpulence><cytokine><declining cognitive functions with aging><dementia risk><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><dietary><dimorphism><electrophysiological><experiment><experimental research><experimental study><experiments><female study><flow cytophotometry><gitter cell><glial activation><glial cell activation><high blood pressure><hippocampal><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><induced Cre><inducible Cre><inducible expression><inducible gene expression><innovate><innovation><innovative><insight><lymph cell><lymphocyte trafficking><machine based learning><male><meninge><mesoglia><metabolic phenotype><metabotype><microglial cell><microgliocyte><nerve cement><neural inflammation><neuroinflammation><neuroinflammatory><neuronal><neuroprotection><neuroprotective><neutralizing antibody><novel><obesity risk><para-hydroxytamoxifen><pathophysiology><perivascular glial cell><pilot study><population aging><primary degenerative dementia><reconstruction><recruit><response><risk factor for dementia><risk for dementia><risk for obesity><risk of obesity><senile dementia of the Alzheimer type><sex based differences><sex dimorphism><sex-dependent differences><sex-related differences><sex-specific differences><sexual dimorphism><sexually dimorphic><sham surgery><social role><spinal fluid><study among females><study among women><study in females><study in women><study on females><study on women><study within women><subcutaneous><subdermal><synapse><tamoxifen metabolite B><thymus derived lymphocyte><trafficking><visceral obesity><weights><white adipose tissue><white blood cell><white blood corpuscle><yellow adipose tissue><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Matthew J Dean

UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, CHAMPAIGN, IL

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$391,600

FY 2026

Project Title

Deciphering the Roles of Endometrial Glycogen Reserves and the Impact of Obesity on Fertility

Grant Number:

5R01HD111706-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/8/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary Over 40% of pregnancies fail in women, most before or during embryo implantation. During this time, embryos are dependent on secretions into the uterine lumen that contains all of the growth factors and nutrients necessary for embryo development. In particular, embryos need glucose. ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Shangang Zhao

UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, SAN ANTONIO, TX

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$387,500

FY 2026

Project Title

Paracrine effects of leptin in regulating visceral fat expansion

Grant Number:

5R01DK138035-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project summary: Visceral adiposity is a major risk factor for the development of metabolic syndrome. A better understanding of visceral fat expansion in the progression of obesity may provide new strategies to treat obesity and its associated metabolic disorders. Visceral fat expansion requires the...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Helena Hillman Laroche

CHILDREN'S MERCY HOSP (KANSAS CITY, MO), KANSAS CITY, MO

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$266,222

FY 2026

Project Title

Addressing social determinants of health in child obesity treatment using community health workers: the role of parental bandwidth in treatment effectiveness - feasibility study for full - scale RCT

Grant Number:

5R01DK139363-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Childhood obesity remains a significant problem which impacts children’s health. Family-focused child obesity treatment is efficacious but unfortunately not all children receive the same benefit, especially racial and ethnic minority groups, those on Medicaid and those with insecure housing. Adverse...

Research Terms

<0-11 years old><12 year old><12 years of age><Accelerometer><Address><Affect><African American><Afro American><Afroamerican><BMI><BMI percentile><BMI z-score><Body mass index><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Child><Child Health><Child Youth><Childhood><Children (0-21)><Clinical Trials><Cognitive><Communities><Community Health Aides><Community Workers><Complex><Data><Diabetes Mellitus><Diet><Dietary intake><Disease><Disorder><Education><Educational aspects><Emotional><Enrollment><Family><Fats><Fatty acid glycerol esters><Feasibility Studies><Food><Food Preferences><Future><Goals><Health><Health Care><Heart Vascular><Hour><Immediate Memory><Impoverished><Intervention><Interview><Jobs><Learning><Learning Difficulty><Measures><Mediator><Medicaid><Mental Health><Mental Hygiene><Mission><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Obesity><Occupations><Outcome><Outcome Measure><Overweight><Parents><Participant><Persons><Population><Poverty><Preparation><Process><Professional Positions><Provider><Psyche structure><Psychological Health><Public Health><Questionnaires><Quetelet index><Randomized><Research><Research Resources><Resources><Risk Factors><Short-Term Memory><Testing><Time><Training><Transportation><Treatment Effectiveness><Treatment Efficacy><Treatment outcome><U.S. Preventative Services Task Force><U.S. Preventative Task Force><U.S. Preventive Services Task Force><U.S. Preventive Task Force><US Preventative Services Task Force><US Preventative Task Force><US Preventive Health Services Task Force><US Preventive Services Task Force><US Preventive Task Force><USPSTF><United States Preventative Services Task Force><United States Preventative Task Force><United States Preventive Services Task Force><United States Preventive Task Force><Visit><Weight><Weight Gain><Weight Increase><Work><accelerometry><acceptability and feasibility><activity monitor><activity tracker><adiposity><age 12><age 12 years><behavioral economics><body weight gain><body weight increase><child adiposity><child obesity><childhood adiposity><childhood obesity><circulatory system><cognitive burden><cognitive load><community health worker><community marginalization><comparable efficacy><comparative efficacy><compare efficacy><compare treatment><corpulence><delivered virtually><determine efficacy><diabetes><diet choice><diet preference><dietary choice><dietary preferences><diets><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><enroll><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><evaluate efficacy><examine efficacy><feasibility testing><flexibility><flexible><food choice><food insecure><food insecurity><food scarcity><fruits and vegetables><housing insecurity><implementation outcomes><improved><improved outcome><innovate><innovation><innovative><insecure housing><insight><intervention efficacy><kids><low food security><marginalization><marginalized community><measurable outcome><mental><moderate-to-vigorous physical activity><novel><obese children><obesity during childhood><obesity in children><obesity intervention><obesity therapy><obesity treatment><outcome measurement><parent><parent role><parental role><pediatric><pediatric obesity><preparations><racial minority group><racial minority individual><racial minority people><racial minority population><randomisation><randomization><randomly assigned><recruit><satisfaction><social><social health determinants><standard of care><sugar><sweetened beverage><therapeutic efficacy><therapy efficacy><treatment comparison><treatment program><trial comparing><twelve year old><twelve years of age><virtual delivery><weights><working memory><wt gain><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michele Lanpher Patel

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$194,076

FY 2026

Project Title

Optimizing self-monitoring in a digital health intervention for weight loss

Grant Number:

5K23DK129805-05

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/15/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Behavioral obesity treatments can produce clinically significant weight loss but are often too costly or intensive to be implemented on a large scale. Standalone digital health interventions offer greater scalability than traditional in-person approaches, but produce only mo...

Research Terms

<21+ years old><Accelerometer><Address><Adult><Adult Human><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavior monitoring><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body Weight><Body Weight Changes><Body Weight decreased><Business-Friendly Atmosphere><Caloric Intake><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cell Phone><Cellular Phone><Cellular Telephone><Chronic Disease><Chronic Illness><Clinical><Clinical Trials><Conditioning Therapy><Coupled><Data><Dedications><Demographic Factors><Diet><Dietary intake><Eating><Energy Intake><Enrollment><Evaluation><Feedback><Food Intake><Goals><Grant><Interdisciplinary Research><Interdisciplinary Study><Intervention><Interview><Investigators><K-Awards><K-Series Research Career Programs><Measures><Mentors><Mentorship><Methodology><Methods><Mobile Phones><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><Obesity><Outcome><Overweight><Paper><Participant><Patients><Persons><Phase><Physical activity><Population><Position><Positioning Attribute><Preparation><Process><Psychosocial Factor><Public Health><Qualifying><Randomization trial><Randomized><Research><Research Career Program><Research Methodology><Research Methods><Research Personnel><Research Resources><Researchers><Resources><Risk><Structure><Testing><Training><Universities><Weight><Weight Change><Weight Loss><Weight Reduction><Work><accelerometry><activity monitor><activity tracker><adiposity><adulthood><behavior change><behavior intervention><behavioral intervention><behavioral monitoring><body weight loss><business-friendly environment><caloric dietary content><career><chronic disorder><clinical significance><clinically significant><collaborative atmosphere><collaborative environment><combat><corpulence><cost><delivered remotely><design><designing><diets><digital><digital health><digital intervention><digital therapeutics><digital therapy><digital tool><digital toolkit><digital treatment><enroll><ethnic minority><iPhone><innovate><innovation><innovative><insight><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><mobile app><mobile application><mobile device application><multiphase optimization strategy><novel><obesity intervention><obesity therapy><obesity treatment><peer-group atmosphere><peer-group environment><portability><post intervention><preparations><programs><psychosocial variables><racial minority><randomisation><randomization><randomized trial><randomly assigned><recruit><remote delivery><research and methods><retention rate><retention strategy><secondary outcome><skills training><smart phone><smartphone><success><theories><wearable><wearable device><wearable electronics><wearable system><wearable technology><wearable tool><wearables><weight loss intervention><weight loss therapy><weight loss treatment><weights><wireless device><wireless electronic><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nancy Ringel

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$193,874

FY 2026

Project Title

Improving Treatment for Urinary Incontinence Among Patients with Obesity and Type 2 Diabetes Mellitus through a Patient-Centered Collaborative Care Model

Grant Number:

1K23DK147855-01

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2026

End Date:

12/31/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT- Urinary incontinence (UI) is a common condition that affects up to 60% of women in their lifetime and is more prevalent among patients with obesity and Type 2 diabetes mellitus (T2DM). UI, obesity, and T2DM share a bidirectional relationship where UI limits exercise essential for managing ...

Research Terms

<21+ years old><Access to Care><Active Follow-up><Acute><Address><Administrator><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Appointment><Assess implementation><BMI><BMI percentile><BMI z-score><Biometrics><Biometry><Biostatistics><Body Weight><Body Weight decreased><Body mass index><Caring><Chronic><Clinic><Clinical><Clinical Trials><Complement><Complement Proteins><Data><Development><Diabetes Mellitus><Diagnosis><Drugs><Effectiveness><Evidence based treatment><Exercise><Face><Federally Qualified Health Center><Female Health><Future><Goals><Health><Health Care><Health Care Team><Health Services><Health Services Accessibility><Implementation assessment><Improve Access><Incontinence><Individual><Intervention><Interview><Investigators><K23 Award><K23 Mechanism><K23 Program><Ketosis-Resistant Diabetes Mellitus><Life Style><Lifestyle><Maturity-Onset Diabetes Mellitus><Medical Care Team><Medication><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentorship><Methods><Modeling><Morbid Obesity><NIDDM><Nature><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Outcome><PARiHS framework><Patient Preferences><Patients><Pelvic Floor Disorders><Pelvic Floor Muscle><Pharmaceutical Preparations><Phase><Physical activity><Physicians><Pilot Projects><Population><Position><Positioning Attribute><Prevalence><Primary Care><Promoting Action on Research Implementation in Health Services framework><QOL><Quality of life><Quetelet index><Research><Research Methodology><Research Methods><Research Personnel><Researchers><Risk><Service delivery model><Service model><Severe obesity><Severities><Shame><Slow-Onset Diabetes Mellitus><Specialty><Stable Diabetes Mellitus><Structure><Survey Instrument><Surveys><T2 DM><T2D><T2DM><Training><Treatment outcome><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Urinary Incontinence><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Woman><Women's Health><Women's prevalence><Work><acceptability and feasibility><access to health care><access to health services><access to services><access to treatment><accessibility of health care><accessibility to health care><accessibility to health services><active followup><adiposity><adult onset diabetes><adulthood><alleviate symptom><ameliorating symptom><availability of services><barrier to care><barrier to health care><barrier to treatment><body weight gain><body weight increase><body weight loss><care access><care delivery><care delivery model><care fragmentation><care preference><care seeking><career><co-morbid><co-morbidity><collaborative care><community based design><community based research><comorbidity><complementation><corpulence><data integration><decrease symptom><demographics><design><designing><develop therapy><developmental><diabetes><diabetes management><diabetes mellitus management><diabetic management><dissemination science><drug/agent><evaluate implementation><evaluation of implementation><evidence base><experience><experiment><experimental research><experimental study><experiments><extreme obesity><faces><facial><female prevalence><female treatment><fewer symptoms><follow up><follow-up><followed up><followup><health care access><health care availability><health care burden><health care delivery model><health care service access><health care service availability><health service access><health services availability><healthy lifestyle><implementation evaluation><implementation framework><implementation research framework><implementation science><implementation science framework><improved><improved outcome><incontinence care><incontinence management><incontinence symptom><integrated care><integrated health care><integrated model of care><intervention design><intervention development><ketosis resistant diabetes><maturity onset diabetes><medical specialties><new approaches><novel><novel approaches><novel strategies><novel strategy><obese patients><obesity management><obstacle to care><obstacle to health care><participant engagement><patient centered><patient engagement><patient oriented><patients with obesity><pilot study><pilot test><prevalence among females><prevalence among women><prevalence in females><prevalence in women><prevalent among females><prevalent among women><prevalent in females><prevalent in women><primary care clinic><primary care clinician><primary care setting><reduce symptoms><relieves symptoms><research and methods><response><screening><screenings><service availability><skills><social stigma><stigma><success><symptom alleviation><symptom reduction><symptom relief><therapy design><therapy development><treat females><treat women><treatment access><treatment among females><treatment among women><treatment design><treatment development><treatment in females><treatment in women><type 2 DM><type II DM><type two diabetes><women's treatment><wt gain><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jacqueline F Hayes

MIRIAM HOSPITAL, PROVIDENCE, RI

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$188,244

FY 2026

Project Title

Developing a Behavioral Weight Loss Intervention for Emerging Adults Implemented within College Health Service Centers

Grant Number:

5K23DK128561-05

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/7/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Forty percent of emerging adults (age 18-25) have overweight or obesity, which is unlikely to remit and has significant health consequences. However, emerging adults are underrepresented in traditional weight loss programs, drop-out at high rates, and have blunted weight lo...

Research Terms

<18 year old><18 years of age><21+ years old><Acceleration><Address><Adherence><Adult><Adult Human><Age><Award><BMI><BMI percentile><BMI z-score><Behavior><Behavioral><Benchmarking><Best Practice Analysis><Body Weight Changes><Body Weight decreased><Body mass index><Calories><Caring><Cognitive><Control Groups><Data><Dedications><Development><Disease remission><Dropout><Early treatment><Eating><Effectiveness of Interventions><Eligibility><Eligibility Determination><Enrollment><Environment><Feedback><Food Intake><Future><Goals><Groups at risk><Health><Health Services><Hospitals><Hybrids><Individual><Institution><Intake><Intervention><Intervention Studies><Interview><Investigators><K23 Award><K23 Mechanism><K23 Program><Life Style><Lifestyle><Maintenance><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Methods><Milk><Modeling><Monitor><Obesity><Outcome><Overweight><People at risk><Persons><Persons at risk><Population><Populations at Risk><Position><Positioning Attribute><Prevalence><Proctor evaluation model><Proctor framework><Proctor multi-level outcomes framework><Proctor multilevel outcomes framework><Proctor process outcomes><Proctor taxonomy><Protocol Screening><Public Health><Quetelet index><Randomized><Remission><Research><Research Activity><Research Personnel><Researchers><Risk><Self Efficacy><Series><Service setting><Statistical Methods><Students><Testing><Time><Training><Training Activity><Translations><Universities><Weight><Weight Change><Weight Loss><Weight Reduction><Weight maintenance regimen><Woman><Work><active control><adiposity><adult adiposity><adult obesity><adult youth><adulthood><adults with obesity><age 18><age 18 years><age group><ages><behavior change><behavior test><behavioral test><benchmark><body weight loss><calorie><career><cohort><college><college student><collegiate><community advisory board><community advisory committee><community advisory panel><corpulence><delivered on-line><delivered online><design><designing><developmental><early adulthood><early therapy><effective intervention><effectiveness trial><efficacy trial><eighteen year old><eighteen years of age><emerging adult><energy balance><enroll><evidence base><experience><facilitators to implementation><flexibility><flexible><formative assessment><formative evaluation><framework by proctor><implementation facilitators><implementation intervention><implementation outcomes><implementation science><improved><intervention design><intervention research><interventional research><interventional study><interventions research><men><novel><obesigenic><obesity intervention><obesity therapy><obesity treatment><obesogenic><on-line delivery><online delivery><pilot test><pilot trial><preference><prevent><preventing><proctor conceptual model><proctor implementation><proctor model><prototype><psychoeducation><randomisation><randomization><randomly assigned><recruit><research study><statistic methods><theories><therapy design><training module><translation><treatment design><university student><web based delivery><weight control><weight gain prevention><weight loss intervention><weight loss program><weight loss programming><weight loss therapy><weight loss treatment><weight management><weights><wt-loss><young adult><young adult age><young adulthood>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Katherine Elizabeth Darling

MIRIAM HOSPITAL, PROVIDENCE, RI

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$188,078

FY 2026

Project Title

Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes

Grant Number:

5K23DK135791-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2023

End Date:

2/28/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Weight bias internalization (WBI), or self-directed weight-based stigma, has been associated with a number of negative physical and mental health consequences for adolescents with obesity, including negative weight- related outcomes (e.g., increased calorie consumption, poor...

Research Terms

<0-11 years old><12-20 years old><13 year old><13 years of age><21+ years old><Address><Adolescence><Adolescent><Adolescent Youth><Adolescent obesity><Adult><Adult Human><Aeroseb-HC><After Care><After-Treatment><Aftercare><Age><Anxiety><Attitude><Award><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BMI><BMI percentile><BMI z-score><BSF-2><BSF2><Behavior Conditioning Therapy><Behavior Control><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Manipulation><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Behavioral Weight Control><Biological Markers><Body Weight decreased><Body mass index><C-reactive protein><Calories><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cetacort><Child><Child Youth><Children (0-21)><Clinical><Clinical Trials><Combined Modality Therapy><Comment><Commentary><Conditioning Therapy><Consumption><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Cyclicity><Data><Dedications><Dermacort><Development><Diabetes Mellitus><Eating Behavior><Eating Disorders><Editorial Comment><Effectiveness><Eldecort><Environment><Exposure to><Fats><Fatty acid glycerol esters><Feedback><Focus Groups><Goals><HPGF><Health><Hepatocyte-Stimulating Factor><Heterogeneity><Hospitals><Hybridoma Growth Factor><Hydrocortisone><Hydrocortone><Hypophysis><Hypophysis Cerebri><Hypothalamic structure><Hypothalamus><Hytone><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Inflammation><Interleukin-6><Intervention><Intervention Trial><Interventional trial><Investigators><K-Awards><K-Series Research Career Programs><K23 Award><K23 Mechanism><K23 Program><Knowledge><MGI-2><Maps><Mental Depression><Mental Health><Mental Hygiene><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Mentorship><Modeling><Multimodal Therapy><Multimodal Treatment><Myeloid Differentiation-Inducing Protein><Nutracort><Obesity><Outcome><Overweight><Pathway interactions><Periodicity><Phase><Phase 1a Trial><Phase Ia Trial><Physiologic><Physiological><Pituitary><Pituitary Gland><Pituitary Nervous System><Plasmacytoma Growth Factor><Prevalence><Proctocort><Proteins, specific or class, C-reactive><Psychologic Stress><Psychological Health><Psychological Stress><Published Comment><Qualifying><Quetelet index><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Randomized, Controlled Trials><Research><Research Career Program><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Rhythmicity><Risk><Self Direction><Self evaluation><Self-Examination><Self-Surveillance><Stress><Structure><Testing><Training><Training Programs><Universities><Viewpoint><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Weight maintenance regimen><Youth><Youth 10-21><acceptability and feasibility><adiposity><adolescence (12-20)><adolescent health><adolescent health outcomes><adulthood><age 13><age 13 years><ages><behavior intervention><behavior test><behavioral control><behavioral intervention><behavioral test><bio-markers><biologic marker><biomarker><body weight gain><body weight increase><body weight loss><calorie><cohort><combination therapy><combined modality treatment><combined treatment><coping><corpulence><critical developmental period><critical period><depression><design><designing><develop therapy><developmental><diabetes><emotional eater><emotional eating><evidence base><experience><feasibility testing><hypothalamic><improved><interferon beta 2><intervention development><intervention effect><intervention refinement><juvenile><juvenile human><kids><loss of control eating><loss of control over eating><multi-modal therapy><multi-modal treatment><novel><obese adolescents><obesity among adolescents><obesity during adolescence><obesity in adolescence><obesity in adolescents><obesity intervention><obesity therapy><obesity treatment><pathway><physical conditioning><physical health><pilot test><pilot trial><post treatment><psychological stresses><psychological stressor><psychosocial stresses><psychosocial stressors><randomisation><randomization><randomized control trial><randomly assigned><research study><response><skills><social stigma><standard care><standard treatment><stigma><stressor><systemic inflammation><systemic inflammatory response><therapy development><thirteen year old><thirteen years of age><treatment development><verbal><weight control><weight management><weights><wt gain><wt-loss><youngster><youth adiposity><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Colin James Orr

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$176,904

FY 2026

Project Title

Understanding and Addressing Food Insecurity and Obesity Among Infant-Parent Dyads

Grant Number:

5K23DK132513-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2025

End Date:

3/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT The proposed K23 Career Development Award will enable Dr. Colin Orr to become an independent physician- researcher with expertise in food insecurity and childhood obesity prevention. Dr. Orr is a general pediatrician whose long-term goal is to design, test, and implement interventions to ad...

Research Terms

<0-11 years old><Address><Affect><American><Attitude><Behavioral><Black><Black race><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Child><Child Development><Child Health><Child Youth><Children (0-21)><Chronic Disease><Chronic Illness><Clinical><Communities><Cross-Sectional Studies><Cross-Sectional Survey><Data><Decrease disparity><Development><Development Plans><Diabetes Mellitus><Disease Frequency Surveys><Economics><Electronics><Elements><Ensure><Family><Feeding behaviors><Food><Funding><Future><Generalized Growth><Gills><Goals><Grant><Growth><Growth and Development><Growth and Development function><High Prevalence><Hispanic><Household><Infant><Infant and Child Development><Ingestive Behavior><Intervention><Investigators><K-Awards><K-Series Research Career Programs><K23 Award><K23 Mechanism><K23 Program><Knowledge><Learning><Length><Life><Link><Literature><Long-term cohort><Longitudinal cohort><Lower disparity><Manuscripts><Measures><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Mentorship><Methodology><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Hispanic><Nonhispanic><North Carolina><Not Hispanic or Latino><Nutrition><Obesity><Outcome><Parents><Pathway interactions><Perception><Physicians><Pilot Projects><Position><Positioning Attribute><Public Health><Qualitative Methods><Questionnaires><Randomized, Controlled Trials><Reporting><Research><Research Career Program><Research Personnel><Research Resources><Research Support><Researchers><Resources><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Schools><Science><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Strategic Planning><Testing><Theory of Change><Time><Tissue Growth><Training><Universities><Weight><Weight Gain><Weight Increase><Work><Writing><acceptability and feasibility><adiposity><analyzing longitudinal><behavior change><body weight gain><body weight increase><career development><child adiposity><child health care provider><child obesity><childhood adiposity><childhood obesity><chronic disorder><cohort><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><corpulence><cross-sectional research study><design><designing><develop therapy><developmental><diabetes><disparity in health><disparity reduction><eating cues><economic><effective intervention><electronic><electronic device><ethnic diversity><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><ethnically diverse><experience><feeding><feeding-related behaviors><food cues><food insecure><food insecurity><food scarcity><food security><health disparity><healthy weight><hunger cues><implementation intervention><implementation science><improved><infant adiposity><infant obesity><infantile obesity><innovate><innovation><innovative><intervention design><intervention development><kids><learned behavior><learning behavior><longitudinal analysis><low food security><meeting><meetings><mitigate disparity><novel><nutrient intake activity><obese children><obesity among infants><obesity during childhood><obesity in children><obesity in infants><obesity intervention><obesity prevention><obesity risk><obesity therapy><obesity treatment><ontogeny><parent><pathway><patient population><pediatric care provider><pediatric health care provider><pediatric obesity><pediatric provider><pediatrician><peer><peer support><pilot study><preference><prevent><prevent obesity><preventing><qualitative reasoning><racial diversity><racial minority group><racial minority individual><racial minority people><racial minority population><racially diverse><randomized control trial><recruit><reduce disparity><reduction in disparity><risk for obesity><risk of obesity><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><skill acquisition><skill development><theories><therapy design><therapy development><treatment design><treatment development><weights><wt gain><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Britny Hildebrandt

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$162,502

FY 2026

Project Title

Dissecting circuits underlying loss of control relevant to binge eating

Grant Number:

5K08DK136916-04

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/1/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Obesity is a critical public health problem associated with substantial morbidity and mortality. Binge eating (BE), a compulsive episodic overeating behavior, is associated with increased rates of obesity and weight gain. Despite the negative impact of BE on physiological health and obesity...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Maggie A Stanislawski

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$158,790

FY 2026

Project Title

The Contribution of Omic Profiles to Weight Loss and Obesity

Grant Number:

5K01HL157658-05

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The development of cardiovascular disease (CVD) is a complex process, with obesity being a major risk factor. Weight loss among overweight/obese individuals is a key component of the primary prevention of CVD, but there is marked variability across individuals in response to lifestyl...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Approaches to prevention><Area><Assay><BMI><BMI percentile><BMI z-score><Bioassay><Bioinformatics><Biological Assay><Biometrics><Biometry><Biostatistics><Blood Sample><Blood Serum><Blood specimen><Body Weight decreased><Body mass index><CVD prevention><Caloric Restriction><Cardiovascular Diseases><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cause of Death><Cell Communication and Signaling><Cell Signaling><Clinical><Colorado><Complex><Coronary Artery Risk Development in Young Adults><Coronary Artery Risk Development in Young Adults Study><Data><Development><Diet><Dietary intake><Disease><Disorder><Dysfunction><Environment><Epidemiology><Ethnic Origin><Ethnicity><Foundations><Functional Metagenomics><Functional disorder><GI microbiome><GI microbiota><Gastrointestinal microbiota><Gene variant><General Taxonomy><Genetic><Genetic Risk><Goals><H+ element><HCHS/SOL Study><HCHS/SOL cohort><Health><Hispanic Community Health Study/Study of Latinos><Human><Hydrogen Ions><Individual><Institution><Intermittent fasting><Intervention><Intervention Studies><Intervention Trial><Interventional trial><Intracellular Communication and Signaling><Investigation><Investigators><K-Awards><K-Series Research Career Programs><Life Style><Lifestyle><Measures><Mediating><Mediation><Mediator><Medical><Mentors><Mentorship><Metabolic dysfunction><Metabolic syndrome><Metagenomics><Methods><Modern Man><Molecular Epidemiology><Multiomic Data><Negotiating><Negotiation><Obesity><Observational Study><Observational epidemiology><Outcome><Overweight><Participant><Pathway interactions><Personalized medical approach><Persons><Phenotype><Physical activity><Physiopathology><Play><Population><Prevention><Prevention approach><Primary Prevention><Process><Protons><Quetelet index><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Research><Research Career Program><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Risk Factors><Risk Reduction><Role><Serum><Shotguns><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Taxonomy><Training><Universities><Weight Loss><Weight Reduction><Work><active followup><adiposity><adulthood><allelic variant><biological signal transduction><body weight loss><calorie restriction><cardiac disease prevention><cardiometabolic><cardiometabolism><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><career><cohort><conference><convention><corpulence><developmental><diaries><dietary><diets><differences due to race><differences in race><differs by race><differs in race><digestive tract microbiome><enteric microbial community><enteric microbiome><enteric microbiota><epidemiologic><epidemiological><ethnic diversity><ethnically diverse><fecal sample><follow up><follow-up><followed up><followup><gastrointestinal microbial flora><gastrointestinal microbiome><genetic epidemiologic study><genetic epidemiology><genetic variant><genomic variant><group intervention><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiome><gut microbiota><gut microbiotic><gut microflora><gut-associated microbiome><high risk><improved><individualized approach><individualized prevention><innovate><innovation><innovative><insight><intervention arm><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal flora><intestinal microbiome><intestinal microbiota><intestinal microflora><intestinal tract microflora><life style intervention><lifestyle intervention><metabolism measurement><metabolomics><metabonomics><multi-ethnic><multiethnic><multiple omic data><new approaches><novel><novel approaches><novel strategies><novel strategy><obese individuals><obese people><obese person><obese population><obese subjects><obesity genetics><obesity intervention><obesity prevention><obesity risk><obesity therapy><obesity treatment><observational research study><observational survey><pathophysiology><pathway><personalization of treatment><personalized approach><personalized medicine><personalized prevention><personalized therapy><personalized treatment><polygenetic risk scores><polygenic risk score><precision approach><precision prevention><predict responsiveness><predicting response><prevent obesity><race based differences><race differences><race related differences><racial difference><racially different><randomisation><randomization><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk for obesity><risk of obesity><risk-reducing><shot gun><skills><social role><stool sample><stool specimen><success><summit><symposia><symposium><tailored approach><treatment arm><waist circumference><weight loss intervention><weight loss therapy><weight loss treatment><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mary Elizabeth Baugh

VIRGINIA POLYTECHNIC INST AND ST UNIV, BLACKSBURG, VA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$132,885

FY 2026

Project Title

The Influence of Obesity and Insulin Sensitivity on Reward Processing and Decision Making

Grant Number:

1K01DK142002-01A1

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/15/2026

End Date:

2/28/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY This proposal is for a K01 Mentored Research Scientist Development Award for Mary Elizabeth Baugh, PhD, RD. Dr. Baugh’s long-term goal is to become an independent investigator studying the synergistic role of metabolic and neural signals on energy balance and eating behaviors and tra...

Research Terms

<Adult-Onset Diabetes Mellitus><Affect><Animal Model><Animal Models and Related Studies><Appetite><Area><Association Learning><Associative Learning><Attenuated><Automobile Driving><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biomedical Research><Brain><Brain Nervous System><Brain region><Calories><Carbohydrates><Cell Communication and Signaling><Cell Signaling><Choice Behavior><Circulation><Clinical><Clinical Trials><Complement><Complement Proteins><Computer Models><Computerized Models><Conditioning Therapy><Corpus Striatum><Corpus striatum structure><Cues><DEXA><DXA><Data><Data Analyses><Data Analysis><Decision Making><Desire for food><Doctor of Philosophy><Dopamine><Drug Therapy><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Eating><Eating Behavior><Encephalon><Environment><Faculty><Food><Food Intake><Food Preferences><Foundations><Functional MRI><Functional Magnetic Resonance Imaging><Future><Goals><Heterogeneity><Human><Humulin R><Hydroxytyramine><Hypothalamic structure><Hypothalamus><Impairment><Individual><Insulin><Insulin Resistance><Intermediary Metabolism><Intervention Studies><Intracellular Communication and Signaling><Investigators><K01 Award><K01 Mechanism><K01 Program><Ketosis-Resistant Diabetes Mellitus><Knowledge><Learning><Maps><Maturity-Onset Diabetes Mellitus><Measures><Mentored Research Scientist Development Award><Mentored Training Award><Mentors><Mentorship><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Mission><Modern Man><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Nerve Impulse Transmission><Nerve Transmission><Neurobiology><Neuronal Transmission><Neurosciences><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nutrient><OGTT><Obesity><Oral Glucose Tolerance Test><Outcome><Pattern><Pavlovian conditioning><Peripheral><Persons><Ph.D.><PhD><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiologic Psychology><Physiological Psychology><Physiology><Pilot Projects><Process><Psychophysiological><Psychophysiology><Public Health><Regular Insulin><Reproducibility><Research><Research Design><Research Institute><Research Personnel><Research Scientist Development Award><Researchers><Rewards><Role><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Striate Body><Striatum><Study Type><T2 DM><T2D><T2DM><Technical Expertise><Therapeutic><Thesaurismosis><Time><Training><Translating><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Update><Work><adiposity><adult onset diabetes><associative conditioning><attenuate><attenuates><axon signaling><axon-glial signaling><axonal signaling><behavior intervention><behavioral intervention><biological signal transduction><brain morphology><burden of disease><burden of illness><calorie><career><classical conditioning><co-morbid><co-morbidity><cognitive neuroscience><comorbidity><complementation><computational modeling><computational models><computational neuroscience><computer based models><computerized modeling><corpulence><customized therapy><customized treatment><data acquisition><data acquisitions><data interpretation><diet choice><diet preference><dietary choice><dietary preferences><disease burden><driving><drug intervention><drug treatment><energy balance><expectation><fMRI><food choice><glia signaling><glial signaling><glycemic control><healthy weight><hypothalamic><improved><individualized medicine><individualized patient treatment><individualized strategies><individualized therapeutic strategy><individualized therapy><individualized treatment><innovate><innovation><innovative><insight><insulin resistant><insulin sensitivity><insulin tolerance><intervention design><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><maturity onset diabetes><member><metabolism disorder><model of animal><nerve signaling><neural><neural imaging><neural network><neural signaling><neuro-imaging><neurobehavioral><neurobiological><neuroimaging><neurological imaging><neuronal signaling><neurotransmission><novel><obesity intervention><obesity therapy><obesity treatment><patient specific therapies><patient specific treatment><personalized strategies><pharmaceutical><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><physiopsychology><pilot study><preference><programs><psycho-physiological><response><reward processing><skills><social role><statistical analysis><striatal><study design><symptom treatment><symptomatic treatment><tailored medical treatment><tailored therapy><tailored treatment><technical skills><tenure process><tenure track><therapy design><treat symptom><treatment design><type 2 DM><type II DM><type two diabetes><unique treatment>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Arin Kettle Oestreich

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$128,084

FY 2026

Project Title

The role of maternal obesity in osteoarthritis

Grant Number:

5K01AR079045-05

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/5/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY In this K01 proposal, Dr. Arin Oestreich, PhD, presents a detailed career development plan that will culminate in an independent academic faculty position. Dr. Oestreich will obtain critical skills in (1) animal models of osteoarthritis (OA), (2) chromatin profiling and transcriptomi...

Research Terms

<21+ years old><ATAC sequencing><ATAC-seq><ATACseq><Acceleration><Adult><Adult Children><Adult Daughters><Adult Human><Adult Offspring><Adult Sons><Affect><Animal Model><Animal Models and Related Studies><Assay for Transposase-Accessible Chromatin using sequencing><BS-seq><Behavior><Bioinformatics><Bisulfite-based sequencing><Blood Serum><Breeding><CDHF7><CDHR8><Candidate Disease Gene><Candidate Gene><Cell Body><Cell Communication and Signaling><Cell Nucleus><Cell Signaling><Cells><Cells Placenta-Tissue><ChIP assay><Chromatin><Coupled><DNA Methyltransferase 3B><DNMT3B gene><DNMT3b><Data><Degenerative Arthritis><Degenerative polyarthritis><Development><Development Plans><Diagnosis><Diet><Dietary Component><Dietary Fatty Acid><Dietary Intervention><Disease><Disorder><Doctor of Philosophy><Drosophila FAT Tumor Suppressor Homolog><Drugs><Embryo><Embryonic><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><FAT atypical cadherin 1><FAT gene><FAT1><Faculty><Fats><Fatty Acids><Fatty acid glycerol esters><Fetal Growth><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Generalized Growth><Generations><Genes><Genetic><Gestation><Goals><Growth><Health><High Fat Diet><High Prevalence><Histologic><Histologically><Humulin R><Hypertension><Inflammation><Inflammatory><Injury><Insulin><Intracellular Communication and Signaling><Investigators><Joints><Knee><Knee joint><Limb Development><ME5><Macrophage><Maternal Nutrition><Maternal diet><Measures><Medial Menisci><Medial meniscus structure><Medication><Meniscus Medialis><Metabolic><Mice><Mice Mammals><Molecular><Morphology><Murine><Mus><Musculoskeletal><Musculoskeletal Development><Musculoskeletal Diseases><Musculoskeletal System><Musculoskeletal System Development><Mφ><N-3 polyunsaturated fatty acid><N-6 Fatty Acids><NAFLD><Normal Placentoma><Novolin R><Nucleic Acid Regulator Regions><Nucleic Acid Regulatory Sequences><Nucleus><Nutrition During Pregnancy><Nutrition Interventions><Nutritional Interventions><Obesity><Omega-3 Fatty Acids><Omega-3 PUFA><Omega-3 Polyunsaturated Fatty Acid><Omega-6 Fatty Acids><Omega-6 PUFAs><Operative Procedures><Operative Surgical Procedures><Osteoarthritis><Osteoarthrosis><Outcome><Overnutrition><Pain><Painful><Ph.D.><PhD><Pharmaceutical Preparations><Placenta><Placenta Embryonic Tissue><Placentome><Population><Position><Positioning Attribute><Predisposition><Pregnancy><Pregnancy Nutrition><Prenatal Nutrition><Progenitor Cells><Regular Insulin><Regulation><Regulatory Regions><Reproduction><Research><Research Personnel><Researchers><Risk><Role><Secondary to><Serum><Severities><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Single-Nucleus Sequencing><Surgical><Surgical Interventions><Surgical Procedure><Susceptibility><Synovitis><Testing><Tissue Growth><Training><Transgenic Mice><Transgenic Organisms><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vitamins><Work><X-ray microtomography><Xray microtomography><adiposity><adulthood><assay for transposase accessible chromatin followed by sequencing><assay for transposase accessible chromatin seq><assay for transposase accessible chromatin sequencing><assay for transposase-accessible chromatin with sequencing><assess effectiveness><biological signal transduction><bisulfite sequencing><bisulfite-seq><candidate validation><career><career development><cartilage degeneration><cartilage degradation><cartilage development><chromatin immunoprecipitation><corpulence><cytokine><degenerative joint disease><design><designing><determine effectiveness><developmental><diet intervention><dietary><diets><drug/agent><effectiveness assessment><effectiveness evaluation><epigenetically><epigenome><evaluate effectiveness><examine effectiveness><fetal><fetal joint development><flow cytophotometry><genetic regulatory element><global gene expression><global transcription profile><hDNA methyltransferase 3b><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypertrophic arthritis><implantation><improved><in utero><inflamed synovial tissue><inflamed synovium><injuries><intra-uterine growth><intrauterine growth><joint damage><joint formation><joint injury><joint trauma><later in life><later life><life span><lifespan><locomotor system><maternal adiposity><maternal nutrition during pregnancy><maternal obesity><micro CT><micro computed tomography><microCT><microtomography><model of animal><mother nutrition><multiomics><multiple omics><musculoskeletal disorder><n-3 Fatty Acids><n-3 PUFA><new approaches><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><novel approaches><novel strategies><novel strategy><nutrititional status during pregnancy><obese individuals><obese people><obese person><obese population><obese subjects><obesity during pregnancy><obesity in pregnancy><obesity-promoting diet><obesogenic Western-style diet><obesogenic diet><obesogenic high fat diet><obesogenic western diet><offspring><omega-3><omega-3s><ontogeny><panomics><pregnancy health><prenatal><pro-obesity diet><progenitor><programs><sNuc-Seq><single nucleus RNA-sequencing><single nucleus seq><single-nucleus RNA-seq><skills><snRNA sequencing><snRNA-seq><social role><stem cells><subchondral bone><surgery><synovial inflammation><synovial joint development><transcriptome><transcriptomics><transgenic><translation strategy><translational approach><translational strategy><unborn><ω-6>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marisa Ann Patti

DREXEL UNIVERSITY, PHILADELPHIA, PA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$111,199

FY 2026

Project Title

Investigating the Role of Phthalates, Phenols, and Their Sources on Phenotypic Variability in Autism

Grant Number:

1K99ES038217-01

Activity Code:

K99

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/3/2026

End Date:

3/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Autism is a neurodevelopmental disorder impacting 1 in 36 children in the US. Children with autism often experience multi-morbidity of other neurodevelopmental disorders (NDDs) and physical health outcomes like obesity and asthma at higher rates than typically developing pee...

Research Terms

<0-11 years old><3 year old><3 years of age><ASD><Address><Asthma><Asthma in Children><Autism><Autism Diagnosis><Autistic Disorder><Award><Biological Markers><Bronchial Asthma><Carbol><Carbolic Acid><Chemical Exposure><Chemicals><Child><Child Health><Child Youth><Childhood Asthma><Children (0-21)><Cognition><Cohort Studies><Data><Data Collection><Data Set><Diet><Early Infantile Autism><Endocrine Disrupter><Endocrine Disrupting Chemicals><Endocrine Disruptors><Endocrine disrupting agent><Environmental Health><Environmental Health Science><Epidemiology><Exposure to><Frequencies><Funding><Future><General Population><General Public><Gestation><Goals><Grant><Health><Heterogeneity><High Prevalence><Hydroxybenzene><Individual><Infantile Autism><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Intervention><Investigation><Kanner's Syndrome><Knowledge><Lead><Maternal Exposure><Maternal Nutrition><Maternal diet><Measures><Mediating><Mediation><Mentorship><Multiple types of exposure><NIH><National Institutes of Health><Negotiating><Negotiation><Neighborhoods><Neurodevelopmental Disorder><Neurologic><Neurological><Neurological Development Disorder><Obesity><Outcome><Participant><Pattern><Pb element><Pediatric asthma><Phenols><Phenotype><Population><Pregnancy><Prevalence><Protocol><Protocols documentation><Questionnaires><Research><Research Design><Risk><Risk Reduction><Role><Rural><Sampling><Source><Study Type><Subgroup><Time><Training><United States National Institutes of Health><Urban Health><Urbanicity><Work><adiposity><age 3><age 3 years><autism spectral disorder><autism spectrum disorder><autistic children><autistic spectrum disorder><bio-markers><biologic marker><biomarker><child adiposity><child obesity><childhood adiposity><childhood obesity><children on the autism spectrum><children with ASD><children with autism><children with autism spectrum disorder><cohort research study><cohort survey><corpulence><data harmonization><dietary><diets><endocrine disrupting compound><epidemiologic><epidemiological><experience><exposed in utero><exposure research><exposure science><fetal exposure><harmonized data><heavy metal Pb><heavy metal lead><improved><in utero exposure><intellectual and developmental disability><intra-uterine environmental exposure><intrauterine environmental exposure><kids><limited intellectual functioning><maternal nutrition during pregnancy><mother nutrition><multi-exposure><multimorbidity><multiple chronic conditions><multiple exposures><multitude of exposure><neurodevelopmental disease><obese children><obesity during childhood><obesity in children><pediatric obesity><peer><personal care products><phthalates><physical conditioning><physical health><prenatal><prenatal exposure><prenatally exposed><programs><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><social role><study design><three year old><three years of age><trait><unborn><urban dwelling><urinary><various exposures><various types of exposure><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Xinshou Ouyang

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 52/100

Likely hiring

Solid budget

Active award

$396,349

FY 2026

Project Title

RNA m6A methylation contributes to hepatic inflammation in obesity-associated NAFLD

Grant Number:

5R01DK134549-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

SPECIFIC AIMS: Obesity-induced metabolic inflammation results in the transition of nonalcoholic fatty liver disease (NAFLD) to steatohepatitis (NASH) [1-3]. Myeloid cell populations such as macrophages have been established as the main driver of metabolic inflammation [4-10]. Single-cell RNA sequenc...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Huaizhu Wu

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 52/100

Likely hiring

Solid budget

Active award

$388,294

FY 2026

Project Title

Inflammation and insulin resistance in aging

Grant Number:

5R01AG065197-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Aging (referring to middle age) is commonly associated with visceral adiposity and insulin resistance. Impaired white adipose tissue (AT) “browning” and reduced energy expenditure that also occur in aging may contribute to age-linked adiposity, yet how AT browning and metabolism are regulated with a...

Research Terms

<9-Octadecenoic Acid><Abdominal obesity><Ablation><Adipocytes><Adipose Cell><Adipose tissue><Age><Aging><Android fat distribution><Assay><Basal Transcription Factor><Basal transcription factor genes><Bioassay><Biological Assay><Body Tissues><Brown Adipose Tissue><Brown Fat><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Central obesity><Centripetal obesity><Clinical><Data><Diet><Disease><Disorder><Dysfunction><Energy Expenditure><Energy Metabolism><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Functional disorder><General Transcription Factor Gene><General Transcription Factors><Hibernating Gland><Human><Immune Cell Activation><Impairment><Inflammation><Insulin Resistance><Intermediary Metabolism><Intracellular Communication and Signaling><KO mice><Knock-out Mice><Knockout Mice><Knowledge><Leanness><Link><Lipocytes><Mature Lipocyte><Mature fat cell><Mediating><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolic dysfunction><Metabolism><Mice><Mice Mammals><Modern Man><Murine><Mus><Null Mouse><Obesity><Oleic Acids><Organ><Pathway interactions><Phosphorylation><Physiopathology><Pilot Projects><Play><Protein Phosphorylation><RNA Seq><RNA sequencing><RNAseq><Regulation><Regulatory T-Lymphocyte><Reporting><Repression><Research Specimen><Role><STAT1><STAT1 gene><STAT91><Signal Transduction><Signal Transduction Systems><Signaling><Specimen><T cell based immune therapy><T cell based therapeutics><T cell based therapy><T cell directed therapies><T cell immune therapy><T cell immunotherapy><T cell targeted therapeutics><T cell therapy><T cell treatment><T cell-based immunotherapy><T cell-based treatment><T cellular immunotherapy><T cellular therapy><T lymphocyte based immunotherapy><T lymphocyte based therapy><T lymphocyte therapeutic><T lymphocyte treatment><T-Cell Proliferation><T-Cells><T-Lymphocyte><T-cell inflamed><T-cell therapeutics><T-cell transfer therapy><Techniques><Testing><Thesaurismosis><Thinness><Tissues><Transcription Factor Proto-Oncogene><Transcription factor genes><Treg><Truncal obesity><Visceral><Weight Gain><Weight Increase><Wild Type Mouse><adipose><adiposity><adoptive T cell transfer><adoptive T lymphocyte transfer><adoptive T-cell therapy><age associated><age correlated><age dependent><age linked><age related><age specific><ages><aging associated><aging related><ameliorating inflammaging><anti-inflammaging><attenuate inflammaging><biological signal transduction><body weight gain><body weight increase><cis-9-Octadecenoic Acid><corpulence><dietary><diets><flow cytophotometry><immune activation><improved><inflammaging mitigation><inhibitor><insulin resistant><insulin sensitivity><insulin tolerance><metabolism disorder><mid life><mid-life><middle age><middle aged><midlife><mitigate age related inflammation><mouse model><murine model><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathophysiology><pathway><pharmacologic><pilot study><prevent><prevent age related inflammation><prevent inflammaging><preventing><reducing age related inflammation><regulatory T-cells><social role><therapeutic T-cell platform><thymus derived lymphocyte><tissue culture><transcription factor><transcriptome sequencing><transcriptomic sequencing><visceral obesity><white adipose tissue><wildtype mouse><wt gain><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jiujiu Yu

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Good lead · 52/100

Likely hiring

Solid budget

Active award

$358,750

FY 2026

Project Title

Role of chive-derived exosome-like nanoparticles in suppressing inflammation in obesity

Grant Number:

5R01DK124590-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/20/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Obesity is a chronic progressive disease that leads to the development of heart disease, stroke, and type 2 diabetes, which are among the top ten leading causes of death in the United States. The initiation and progression of obesity-related diseases is strongly associated with chronic low-grade inf...

Research Terms

<Adult-Onset Diabetes Mellitus><Allium schoenoprasum><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Apoplexy><Bioavailability><Biological Availability><Body Tissues><Brain Vascular Accident><Cardiac Diseases><Cardiac Disorders><Cause of Death><Cell Body><Cells><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chemical Structure><Chemicals><Chive><Choline Chloride Dihydrogen Phosphate><Choline Phosphate><Choline Phosphate Chloride><Chronic><Complex><Development><Diet><Dietary Fats><Disease><Disease Progression><Disorder><Dose><Edible Plants><Financial Hardship><Food Plants><Fruit><Gene Expression><Goals><Health><Heart Diseases><High Fat Diet><Human><Individual><Inflammasome><Inflammation><Innate Immune System><Intervention><Ketosis-Resistant Diabetes Mellitus><Lipids><Macrophage><Manuscripts><Maturity-Onset Diabetes Mellitus><Mediating><Membrane><Metabolic><Mice><Mice Mammals><Milk><Modality><Modern Man><Murine><Mus><Mφ><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Polyadenylated RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutraceutical><Obesity><Obesity associated disease><Obesity related disease><Oral><Oral Administration><Oral Drug Administration><Outcomes Research><Patients><Persons><Phosphocholine><Phosphorylcholine><Phosphorylcholine Chloride><Physiologic Availability><Pilot Projects><Progressive Disease><Proteins><RNA><RNA Gene Products><Research><Ribonucleic Acid><Risk><Role><Slow-Onset Diabetes Mellitus><Societies><Stable Diabetes Mellitus><Stroke><T2 DM><T2D><T2DM><Testing><Therapeutic><Therapeutic Effect><Tissues><Translating><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Vegetables><Work><adiposity><adult onset diabetes><brain attack><cerebral vascular accident><cerebrovascular accident><chemical reduction><clinical practice><combat><corpulence><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><dietary><dietary fruit><dietary lipid><dietary vegetable><diets><economic hardship><economic strain><exosome><feeding><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><gene function><heart disorder><improved><inhibitor><innovate><innovation><innovative><intraoral drug delivery><ketosis resistant diabetes><lipophilicity><maturity onset diabetes><membrane structure><nano particle><nano-sized particle><nanocarrier><nanoparticle><nanosized particle><nanovessel><particle><pilot study><prevent><preventing><sensor><social role><stroked><strokes><translation><translational applications><translational opportunities><translational potential><type 2 DM><type II DM><type two diabetes>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mary Dawn Koenig

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 52/100

Likely hiring

Solid budget

Active award

$314,832

FY 2026

Project Title

A pilot study of time-restricted eating among pregnant females with severe obesity

Grant Number:

5R01DK136085-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT In the United States, severe obesity (BMI ≥ 40.0 kg/m2) disproportionally affects non-Hispanic Black females of reproductive age. Severe obesity is a significant predictor of adverse perinatal outcomes including gestational diabetes mellitus (GDM), pre-eclampsia, premature birth, and at its...

Research Terms

<2nd trimester><37 weeks completed gestation><37 weeks gestation><3rd trimester><Abdominal Delivery><Acceleration><Adherence><Admission><Admission activity><Adoption><Adverse Experience><Adverse event><Affect><BMI><BMI percentile><BMI z-score><Birth><Birth Defects><Black><Black race><Blood Glucose><Blood Pressure><Blood Sugar><Body Weight><Body fat><Body mass index><C section><C-reactive protein><Caloric Restriction><Calories><Caucasian Females><Caucasian Women><Cesarean><Cesarean section><Chronologic Fetal Maturity><Clinic><Clinical><Clinical Data><Clinical Trials><Congenital Abnormality><Congenital Anatomical Abnormality><Congenital Defects><Congenital Deformity><Congenital Malformation><Consumption><D-Glucose><Data><Data Collection><Dextrose><Diet><Dietary Practices><Dietary quality><Disease><Disorder><EPH Gestosis><Eating><Electronic Health Record><Eligibility><Eligibility Determination><Enrollment><Ethnic Origin><Ethnicity><Event><Fasting><Fetal Age><Fetal Death><Fetal Growth><Fetal health><Financial Hardship><Food><Food Intake><Food Preferences><Funding><Generalized Growth><Gestation><Gestational Age><Gestational Diabetes><Gestational Diabetes Mellitus><Gestational Hypertension><Glucose><Goals><Growth><Health><Health Food><High Prevalence><Hispanic Females><Hispanic Women><Humulin R><Hypertension induced by pregnancy><Individual><Insulin><Intermittent fasting><Intervention><Intervention Studies><Interview><Isoprostanes><Labor and Delivery><Last Trimester><Lipids><Maternal Health><Maternal Mortality><Medical><Metabolic><Midtrimester><Mission><Monitor><Morbid Obesity><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Novolin R><Nutritionist><Nutritious food><Obesity><Observational Study><Outcome><Oxidative Stress><Participant><Parturition><Patients><Pattern><Perinatal><Peripartum><Personal Satisfaction><Persons><Physical activity><Pilot Projects><Population><Pre-Eclampsia><Preeclampsia><Pregnancy><Pregnancy Associated Hypertension><Pregnancy Toxemias><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Premature Labor><Premature Obstetric Labor><Prematurely delivering><Prenatal care><Preterm Birth><Preterm Labor><Proteins, specific or class, C-reactive><Proteinuria-Edema-Hypertension Gestosis><Protocol Screening><Public Health><Quetelet index><Race><Races><Regimen><Regular Insulin><Research><Research Infrastructure><Risk><Risk Marker><Safety><Second Pregnancy Trimester><Second Trimester><Severe obesity><Subgroup><Third Pregnancy Trimester><Third Trimester><Time-restricted eating><Time-restricted feeding><Tissue Growth><Translating><United States><United States National Institutes of Health><Veins><Visit><Weight><Weight maintenance regimen><White Females><White Women><Work><acceptability and feasibility><adiposity><adult adiposity><adult obesity><adults with obesity><arm><black female><black women><calorie><calorie restriction><cardiometabolic risk><childbearing age><corpulence><diet choice><diet preference><diet quality><dietary choice><dietary pattern><dietary preferences><diets><economic hardship><economic strain><efficacy trial><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><excessive weight gain><expectant mother><expectant women><expecting mother><expecting women><extreme obesity><extreme weight gain><fasted><fasts><fertile age><fetal><fetus death><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><food choice><food monitoring><food restriction><food supply monitoring><food supply surveillance><food surveillance><gestational weight gain><healthy food><hypertension during pregnancy><hypertension in pregnancy><hypertensive pregnancy><improved><individuals who are pregnant><innovate><innovation><innovative><interest><intervention research><interventional research><interventional study><interventions research><intra-uterine growth><intrauterine growth><life style intervention><lifestyle intervention><maternal death><maternal risk><meeting><meetings><member><neonatal health><newborn health><observational research study><observational survey><ontogeny><people who are pregnant><perinatal health><perinatal outcomes><perinatal period><perinatal phase><pilot study><pre-eclamptic><pregnancy care><pregnancy characterized by hypertension><pregnancy diabetes><pregnancy hypertension><pregnancy toxemia/hypertension><pregnancy-related hypertension><pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prenatal appointment><prenatal checkup><prenatal visit><preterm delivery><prevent><preventing><programs><racial><racial background><racial origin><reproductive age><reproductive years><response><risk predictor><risk predictors><safety testing><serious weight gain><severe weight gain><standard care><standard treatment><those who are pregnant><weight control><weight maintenance><weight management><weights><well-being><wellbeing><women who are pregnant>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lisa Tussing-Humphreys

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 52/100

Likely hiring

Solid budget

Active award

$314,832

FY 2026

Project Title

A pilot study of time-restricted eating among pregnant females with severe obesity

Grant Number:

5R01DK136085-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT In the United States, severe obesity (BMI ≥ 40.0 kg/m2) disproportionally affects non-Hispanic Black females of reproductive age. Severe obesity is a significant predictor of adverse perinatal outcomes including gestational diabetes mellitus (GDM), pre-eclampsia, premature birth, and at its...

Research Terms

<2nd trimester><37 weeks completed gestation><37 weeks gestation><3rd trimester><Abdominal Delivery><Acceleration><Adherence><Admission><Admission activity><Adoption><Adverse Experience><Adverse event><Affect><BMI><BMI percentile><BMI z-score><Birth><Birth Defects><Black><Black race><Blood Glucose><Blood Pressure><Blood Sugar><Body Weight><Body fat><Body mass index><C section><C-reactive protein><Caloric Restriction><Calories><Caucasian Females><Caucasian Women><Cesarean><Cesarean section><Chronologic Fetal Maturity><Clinic><Clinical><Clinical Data><Clinical Trials><Congenital Abnormality><Congenital Anatomical Abnormality><Congenital Defects><Congenital Deformity><Congenital Malformation><Consumption><D-Glucose><Data><Data Collection><Dextrose><Diet><Dietary Practices><Dietary quality><Disease><Disorder><EPH Gestosis><Eating><Electronic Health Record><Eligibility><Eligibility Determination><Enrollment><Ethnic Origin><Ethnicity><Event><Fasting><Fetal Age><Fetal Death><Fetal Growth><Fetal health><Financial Hardship><Food><Food Intake><Food Preferences><Funding><Generalized Growth><Gestation><Gestational Age><Gestational Diabetes><Gestational Diabetes Mellitus><Gestational Hypertension><Glucose><Goals><Growth><Health><Health Food><High Prevalence><Hispanic Females><Hispanic Women><Humulin R><Hypertension induced by pregnancy><Individual><Insulin><Intermittent fasting><Intervention><Intervention Studies><Interview><Isoprostanes><Labor and Delivery><Last Trimester><Lipids><Maternal Health><Maternal Mortality><Medical><Metabolic><Midtrimester><Mission><Monitor><Morbid Obesity><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Novolin R><Nutritionist><Nutritious food><Obesity><Observational Study><Outcome><Oxidative Stress><Participant><Parturition><Patients><Pattern><Perinatal><Peripartum><Personal Satisfaction><Persons><Physical activity><Pilot Projects><Population><Pre-Eclampsia><Preeclampsia><Pregnancy><Pregnancy Associated Hypertension><Pregnancy Toxemias><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Premature Labor><Premature Obstetric Labor><Prematurely delivering><Prenatal care><Preterm Birth><Preterm Labor><Proteins, specific or class, C-reactive><Proteinuria-Edema-Hypertension Gestosis><Protocol Screening><Public Health><Quetelet index><Race><Races><Regimen><Regular Insulin><Research><Research Infrastructure><Risk><Risk Marker><Safety><Second Pregnancy Trimester><Second Trimester><Severe obesity><Subgroup><Third Pregnancy Trimester><Third Trimester><Time-restricted eating><Time-restricted feeding><Tissue Growth><Translating><United States><United States National Institutes of Health><Veins><Visit><Weight><Weight maintenance regimen><White Females><White Women><Work><acceptability and feasibility><adiposity><adult adiposity><adult obesity><adults with obesity><arm><black female><black women><calorie><calorie restriction><cardiometabolic risk><childbearing age><corpulence><diet choice><diet preference><diet quality><dietary choice><dietary pattern><dietary preferences><diets><economic hardship><economic strain><efficacy trial><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><excessive weight gain><expectant mother><expectant women><expecting mother><expecting women><extreme obesity><extreme weight gain><fasted><fasts><fertile age><fetal><fetus death><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><food choice><food monitoring><food restriction><food supply monitoring><food supply surveillance><food surveillance><gestational weight gain><healthy food><hypertension during pregnancy><hypertension in pregnancy><hypertensive pregnancy><improved><individuals who are pregnant><innovate><innovation><innovative><interest><intervention research><interventional research><interventional study><interventions research><intra-uterine growth><intrauterine growth><life style intervention><lifestyle intervention><maternal death><maternal risk><meeting><meetings><member><neonatal health><newborn health><observational research study><observational survey><ontogeny><people who are pregnant><perinatal health><perinatal outcomes><perinatal period><perinatal phase><pilot study><pre-eclamptic><pregnancy care><pregnancy characterized by hypertension><pregnancy diabetes><pregnancy hypertension><pregnancy toxemia/hypertension><pregnancy-related hypertension><pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prenatal appointment><prenatal checkup><prenatal visit><preterm delivery><prevent><preventing><programs><racial><racial background><racial origin><reproductive age><reproductive years><response><risk predictor><risk predictors><safety testing><serious weight gain><severe weight gain><standard care><standard treatment><those who are pregnant><weight control><weight maintenance><weight management><weights><well-being><wellbeing><women who are pregnant>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Krista Amy Varady

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 52/100

Likely hiring

Solid budget

Active award

$314,832

FY 2026

Project Title

A pilot study of time-restricted eating among pregnant females with severe obesity

Grant Number:

5R01DK136085-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT In the United States, severe obesity (BMI ≥ 40.0 kg/m2) disproportionally affects non-Hispanic Black females of reproductive age. Severe obesity is a significant predictor of adverse perinatal outcomes including gestational diabetes mellitus (GDM), pre-eclampsia, premature birth, and at its...

Research Terms

<2nd trimester><37 weeks completed gestation><37 weeks gestation><3rd trimester><Abdominal Delivery><Acceleration><Adherence><Admission><Admission activity><Adoption><Adverse Experience><Adverse event><Affect><BMI><BMI percentile><BMI z-score><Birth><Birth Defects><Black><Black race><Blood Glucose><Blood Pressure><Blood Sugar><Body Weight><Body fat><Body mass index><C section><C-reactive protein><Caloric Restriction><Calories><Caucasian Females><Caucasian Women><Cesarean><Cesarean section><Chronologic Fetal Maturity><Clinic><Clinical><Clinical Data><Clinical Trials><Congenital Abnormality><Congenital Anatomical Abnormality><Congenital Defects><Congenital Deformity><Congenital Malformation><Consumption><D-Glucose><Data><Data Collection><Dextrose><Diet><Dietary Practices><Dietary quality><Disease><Disorder><EPH Gestosis><Eating><Electronic Health Record><Eligibility><Eligibility Determination><Enrollment><Ethnic Origin><Ethnicity><Event><Fasting><Fetal Age><Fetal Death><Fetal Growth><Fetal health><Financial Hardship><Food><Food Intake><Food Preferences><Funding><Generalized Growth><Gestation><Gestational Age><Gestational Diabetes><Gestational Diabetes Mellitus><Gestational Hypertension><Glucose><Goals><Growth><Health><Health Food><High Prevalence><Hispanic Females><Hispanic Women><Humulin R><Hypertension induced by pregnancy><Individual><Insulin><Intermittent fasting><Intervention><Intervention Studies><Interview><Isoprostanes><Labor and Delivery><Last Trimester><Lipids><Maternal Health><Maternal Mortality><Medical><Metabolic><Midtrimester><Mission><Monitor><Morbid Obesity><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Novolin R><Nutritionist><Nutritious food><Obesity><Observational Study><Outcome><Oxidative Stress><Participant><Parturition><Patients><Pattern><Perinatal><Peripartum><Personal Satisfaction><Persons><Physical activity><Pilot Projects><Population><Pre-Eclampsia><Preeclampsia><Pregnancy><Pregnancy Associated Hypertension><Pregnancy Toxemias><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Premature Labor><Premature Obstetric Labor><Prematurely delivering><Prenatal care><Preterm Birth><Preterm Labor><Proteins, specific or class, C-reactive><Proteinuria-Edema-Hypertension Gestosis><Protocol Screening><Public Health><Quetelet index><Race><Races><Regimen><Regular Insulin><Research><Research Infrastructure><Risk><Risk Marker><Safety><Second Pregnancy Trimester><Second Trimester><Severe obesity><Subgroup><Third Pregnancy Trimester><Third Trimester><Time-restricted eating><Time-restricted feeding><Tissue Growth><Translating><United States><United States National Institutes of Health><Veins><Visit><Weight><Weight maintenance regimen><White Females><White Women><Work><acceptability and feasibility><adiposity><adult adiposity><adult obesity><adults with obesity><arm><black female><black women><calorie><calorie restriction><cardiometabolic risk><childbearing age><corpulence><diet choice><diet preference><diet quality><dietary choice><dietary pattern><dietary preferences><diets><economic hardship><economic strain><efficacy trial><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><excessive weight gain><expectant mother><expectant women><expecting mother><expecting women><extreme obesity><extreme weight gain><fasted><fasts><fertile age><fetal><fetus death><financial adversity><financial burden><financial distress><financial insecurity><financial instability><financial strain><financial stress><financial worry><food choice><food monitoring><food restriction><food supply monitoring><food supply surveillance><food surveillance><gestational weight gain><healthy food><hypertension during pregnancy><hypertension in pregnancy><hypertensive pregnancy><improved><individuals who are pregnant><innovate><innovation><innovative><interest><intervention research><interventional research><interventional study><interventions research><intra-uterine growth><intrauterine growth><life style intervention><lifestyle intervention><maternal death><maternal risk><meeting><meetings><member><neonatal health><newborn health><observational research study><observational survey><ontogeny><people who are pregnant><perinatal health><perinatal outcomes><perinatal period><perinatal phase><pilot study><pre-eclamptic><pregnancy care><pregnancy characterized by hypertension><pregnancy diabetes><pregnancy hypertension><pregnancy toxemia/hypertension><pregnancy-related hypertension><pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prenatal appointment><prenatal checkup><prenatal visit><preterm delivery><prevent><preventing><programs><racial><racial background><racial origin><reproductive age><reproductive years><response><risk predictor><risk predictors><safety testing><serious weight gain><severe weight gain><standard care><standard treatment><those who are pregnant><weight control><weight maintenance><weight management><weights><well-being><wellbeing><women who are pregnant>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KC KENT LLOYD

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 48/100

Above-average budget

Recent

Active award

Team-scale grant

$764,750

FY 2026

Project Title

The National Center for Metabolic Phenotyping of Mouse Models of Obesity and Diabetes (MPMOD) at UC Davis

Grant Number:

5U2CDK135074-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. Translational research in vivo using genetic, surgical, humanized, and other types of mouse models are needed to decipher the heterogeneity of diabetes, obesity, and ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Julio E Ayala

VANDERBILT UNIVERSITY, Nashville, TN

Good lead · 48/100

Above-average budget

Recent

Active award

Team-scale grant

$753,517

FY 2026

Project Title

Vanderbilt Center for Metabolic Phenotyping in Live Models of Obesity and Diabetes

Grant Number:

5U2CDK135073-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. Overall Center The Vanderbilt Center for Metabolic Phenotyping in Live Models of Obesity and Diabetes (VMPMOD) is built on the strong Vanderbilt history of serving as ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

GERALD I SHULMAN

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 48/100

Above-average budget

Recent

Active award

Team-scale grant

$745,837

FY 2026

Project Title

Yale Center for Metabolic Phenotyping in Live Models of Obesity and Diabetes

Grant Number:

5U2CDK134901-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. The overarching goal of the Yale MMPC-Live is to provide extramural investigators access to the unique metabolic phenotyping services provided by the Yale MMPC-Live an...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Carol Fuzeti Elias

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 48/100

Above-average budget

Recent

Active award

Team-scale grant

$692,295

FY 2026

Project Title

Metabolic Phenotyping in Live Models of Obesity and Diabetes

Grant Number:

5U2CDK135066-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

Metabolic disorders, including obesity, diabetes and their complications are among the most pressing health issues worldwide accounting for a substantial national burden of morbidity, mortality, and healthcare costs. The University of Michigan Health System (now Michigan Medicine) has strategically ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Justin Brigham Dimick

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 48/100

Training-friendly

Very recent

Active award

$229,983

FY 2026

Project Title

Obesity & Gastrointestinal Surgery Research Training Program

Grant Number:

5T32DK108740-09

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2016

End Date:

3/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY ABSTRACT Overview: Obesity and gastrointestinal diseases are among the most common indications for surgery (e.g., bariatric surgery, gastroesophageal reflux, hernias, diverticulitis, etc…). However, there are considerably fewer scientists studying these topics compared to other clini...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RANDY J SEELEY

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 48/100

Training-friendly

Very recent

Active award

$229,983

FY 2026

Project Title

Obesity & Gastrointestinal Surgery Research Training Program

Grant Number:

5T32DK108740-09

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2016

End Date:

3/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY ABSTRACT Overview: Obesity and gastrointestinal diseases are among the most common indications for surgery (e.g., bariatric surgery, gastroesophageal reflux, hernias, diverticulitis, etc…). However, there are considerably fewer scientists studying these topics compared to other clini...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Zachary Mathias Harvanek

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$195,156

FY 2026

Project Title

Psychological and Epigenetic Predictors of Obesity & Metabolic Disease

Grant Number:

5K23DK136932-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT This proposal seeks to investigate the predictive ability of psychological and epigenetic markers for success of lifestyle interventions in patients with obesity. Obesity is a growing public health crisis, and in the coming decades it is expected that 50% of Americans will h...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Caitlin Smith

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$190,580

FY 2026

Project Title

A Multiple Health Behavior Change Intervention for Weight-Loss and Smoking Cessation among Pre-Bariatric Surgery Patients

Grant Number:

1K23DA064898-01

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Smoking prevalence among pre-bariatric surgery patients is estimated to be as high as 40%. In addition to quitting smoking, patients are expected to lose weight before surgery, which is challenging as smoking cessation is associated with weight gain. Pre-bariatric surgery pa...

Research Terms

<21+ years old><Abstinence><Active Follow-up><Address><Adult><Adult Human><After Care><After-Treatment><Aftercare><Amfebutamone><BMI><BMI percentile><BMI z-score><Back><Bariatrics><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biochemical><Body Weight decreased><Body mass index><Bupropion><Business-Friendly Atmosphere><Carbon Monoxide><Clinical Practice Guideline><Clinical Treatment><Clinical Trials><Cognitive><Combined Modality Therapy><Conditioning Therapy><Conduct Clinical Trials><Control Groups><Data><Development><Dorsum><Drug Therapy><Drugs><Eating><Educational workshop><Enrollment><Environment><Evaluation><Exhalation><Exhaling><Exhibits><FDA approved><Feedback><Food Intake><Goals><Grant><Health><Health behavior change><Individual><Interdisciplinary Research><Interdisciplinary Study><Intervention><Intervention Studies><Interview><Investigators><Knowledge><Laboratories><Leadership><Learning><Liver><Measures><Medication><Mentors><Methodology><Methods><Modeling><Morbid Obesity><Morbidity><Multidisciplinary Collaboration><Multidisciplinary Research><Multimodal Therapy><Multimodal Treatment><Nalorex><Naltrexone><Nemexin><Obesity><Operative Procedures><Operative Surgical Procedures><Outcome><Outcome Assessment><Outcome Measure><Participant><Patients><Pharmaceutical Preparations><Pharmacological Treatment><Pharmacotherapy><Population><Postoperative><Postoperative Period><Productivity><Psychiatry><Quetelet index><Randomized, Controlled Trials><ReVia><Recommendation><Reporting><Research><Research Activity><Research Ethics><Research Methodology><Research Methods><Research Personnel><Research Resources><Researchers><Resources><Respiratory Expiration><Risk><Risk Behaviors><Risk Reduction><Risky Behavior><Sampling><Severe obesity><Smoke><Smoking><Smoking Cessation Intervention><Supervision><Surgical><Surgical Interventions><Surgical Procedure><Survey Instrument><Surveys><Testing><Tobacco><Training><Treatment Efficacy><United States><Vivitrol><Weight><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Wellbutrin><Work><Workshop><acceptability and feasibility><active followup><adiposity><adulthood><at risk behavior><bariatric surgery><behavior intervention><behavioral intervention><body weight gain><body weight increase><body weight loss><buproprion><business-friendly environment><career development><cease smoking><cigarette smoke><cigarette smoking><cigarette use><clinical intervention><clinical practice and guidelines><clinical therapy><collaborative atmosphere><collaborative environment><combination therapy><combined modality treatment><combined treatment><compare intervention><compare to control><comparison control><comparison intervention><conference><convention><corpulence><cross sectional prevalence><design><designing><develop therapy><developmental><dosage><drug intervention><drug treatment><drug/agent><effective intervention><enroll><evidence base><experience><extreme obesity><follow up><follow-up><followed up><followup><gastric banding><gastric bypass surgery><hepatic body system><hepatic organ system><high risk><implantable gastric stimulation banding><improved><innovate><innovation><innovative><insulin sensitivity><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><intervention arm><intervention development><intervention efficacy><intervention refinement><intervention research><interventional research><interventional study><interventions research><measurable outcome><meeting><meetings><multi-modal therapy><multi-modal treatment><never smoker><obesity intervention><obesity surgery><obesity therapy><obesity treatment><outcome measurement><participant enrollment><patient enrollment><patient population><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><peer-group atmosphere><peer-group environment><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><point prevalence><population health><post treatment><preventable death><preventable mortality><programs><prospective><pulmonary><quit smoking><randomized control trial><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><relapse risk><research and methods><response><risk-reducing><satisfaction><skills><smoking abstinence><smoking cessation><smoking cessation treatment><smoking prevalence><smoking relapse><standard of care><stomach stapling><stop smoking><summit><surgery><symposia><symposium><therapeutic efficacy><therapy development><therapy efficacy><timeline><tissue wound><treatment arm><treatment development><treatment trial><trial comparing><trial regimen><trial treatment><weight loss intervention><weight loss surgery><weight loss therapy><weight loss treatment><weights><wound><wounding><wounds><wt gain><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christine Call

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$189,754

FY 2026

Project Title

Longitudinal and Momentary Associations Underlying the Relation of Food Insecurity and Gestational Weight Gain: Toward Obesity Risk Prevention

Grant Number:

5K23DK136927-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Dr. Christine Call, PI of the proposed K23, is a clinical psychologist with a long-term career goal of leading a program of research focused on health promotion during high-risk times for problematic eating, excess weight gain, and obesity, such as pregnancy and postpartum (i.e., the perinatal perio...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jaime M. Moore

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$185,338

FY 2026

Project Title

Physiologic response to bariatric surgery and the impact of adjunct semaglutide - in adolescents (the PRESSURE trial)

Grant Number:

5K23HL163480-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Metabolic and bariatric surgery (MBS) to treat pediatric severe obesity is increasingly common. MBS at younger ages means decades longer to preserve or enhance its cardiometabolic and other health benefits. While mean weight loss after MBS is substantial, >50% of adolescents...

Research Terms

<12-20 years old><21+ years old><Adherence><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Agonist><Anti-Obesity Agents><Anti-Obesity Drugs><Apoplexy><Appetite><BMI><BMI percentile><BMI z-score><Basal Metabolism><Basal metabolic rate><Behavioral><Biological><Blood Pressure><Blood Pressure Monitors><Body Composition><Body Weight><Body Weight decreased><Body mass index><Brain Vascular Accident><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Childhood><Clinical><Clinical Treatment><Clinical Trials><Continuous Sphygmomanometers><DEXA><DXA><Data><Death><Desire for food><Development Plans><Disease remission><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drug Therapy><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Eating Behavior><Echocardiogram><Echocardiography><Environment><Fasting><Fats><Fatty acid glycerol esters><Funding><Future><GLP-1><GLP-1 receptor><GLP-I receptor><Gastrectomy><Gastric Inhibitory Polypeptide><Glp-1><Glucose-Dependent Insulin-Releasing Peptide><Glucose-Dependent Insulinotropic Peptide><Goals><Grant><Health><Health Benefit><Heart Vascular><Hispanic><Hour><Hypertension><Indirect Calorimetry><Individual><Injectable><Intervention><Intervention Trial><Interventional trial><Ketosis-Resistant Diabetes Mellitus><L-tyrosyl-L-tyrosine><Learning><Life Style><Lifestyle><Link><Maturity-Onset Diabetes Mellitus><Measures><Mechanics><Medicine><Mental Health><Mental Hygiene><Metabolic><Methods><Morbid Obesity><Morbidity><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition><Obesity><Operative Procedures><Operative Surgical Procedures><Outcome><PYY Peptide><Peptide YY><Peptides><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiologic><Physiologic pulse><Physiological><Physiology><Placebos><Postoperative><Postoperative Period><Predictive Factor><Prospective Studies><Protocol><Protocols documentation><Psychological Health><Publications><Pulse><Quetelet index><Randomized><Randomized, Controlled Trials><Remission><Reporting><Research><Research Design><Residual><Residual state><Respiration Calorimetry><Risk><Risk Factors><Risk Marker><Risk Reduction><Satiation><Scientific Publication><Severe obesity><Sham Treatment><Slow-Onset Diabetes Mellitus><Social Environment><Solid><Stable Diabetes Mellitus><Stroke><Structure><Study Type><Surgical><Surgical Interventions><Surgical Procedure><T2 DM><T2D><T2DM><Testing><Training><Transthoracic Echocardiography><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Tyr-Tyr><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Weight><Weight Loss><Weight Reduction><Weight maintenance regimen><Youth><Youth 10-21><adiposity><adolescence (12-20)><adult onset diabetes><adulthood><anti-obesity compounds><anti-obesity medications><anti-obesity therapeutics><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><bariatric surgery><biologic><body weight loss><brain attack><cardiometabolic><cardiometabolic risk><cardiometabolism><cardiovascular disorder><cardiovascular health><career development><cerebral vascular accident><cerebrovascular accident><child adiposity><child obesity><childhood adiposity><childhood obesity><circulatory system><clinical intervention><clinical therapy><co-morbid><co-morbidity><cohort><comorbidity><corpulence><diagnostic tool><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug intervention><drug treatment><energy balance><experience><extreme obesity><fasted><fasts><gastric banding><gastric bypass surgery><gastric inhibitory peptide><gastrointestinal><ghrelin><glucagon-like peptide 1><glucagon-like peptide-1 receptor><heart rate variability><heart sonography><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implantable gastric stimulation banding><improved><insulin secretion><insulin sensitivity><insulin sensitivity test><insulin tolerance test><insulin-induced hypoglycemia test><intervention design><juvenile><juvenile human><ketosis resistant diabetes><maturity onset diabetes><mechanic><mechanical><obese children><obesity during childhood><obesity in children><obesity surgery><pediatric><pediatric department><pediatric obesity><peptide tyrosine-tyrosine><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><phase 2 designs><phase II designs><physical conditioning><physical health><predict responsiveness><predicting response><premature><prematurity><preservation><professor><prospective><prospective research study><prospective survey><psychologic><psychological><randomisation><randomization><randomized control trial><randomly assigned><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><resting metabolic rate><risk predictor><risk predictors><risk stratification><risk-reducing><satiety><sham therapy><social climate><social context><social stigma><socioenvironment><socioenvironmental><standard of care><stigma><stomach stapling><stratify risk><stroked><strokes><study design><success><surgery><therapy design><treatment design><trial regimen><trial treatment><type 2 DM><type II DM><type two diabetes><tyrosyltyrosine><weight control><weight loss surgery><weight management><weights><wt-loss><younger age><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Pamela Alejandra Mattar Aranguiz

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$167,363

FY 2026

Project Title

Novel CNS mechanisms to combat obesity

Grant Number:

1K01DK146232-01

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Summary Obesity is characterized by visceral fat accrual and lipid spillover to liver and heart, driven largely by systemic insulin resistance. Key drivers of obesity are excessive feeding and reduced energy expenditure. Consequently, understanding the mechanisms that control feeding and/or energy e...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christy M Gliniak

RUTGERS, THE STATE UNIV OF N.J., PISCATAWAY, NJ

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$160,757

FY 2026

Project Title

Interaction of Mesenteric Adipose Tissue Physiology, Expansion, and Inflammation with Inflammatory Bowel Disease

Grant Number:

5K01DK131252-04

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2023

End Date:

2/28/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary Over the past two decades there has been a dramatic increase in the prevalence of inflammatory bowel disease (IBD) such as ulcerative colitis and Crohn's disease, coincident with the obesity epidemic. Obesity and adipose tissue inflammation are linked to whole-body metabolic disturba...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kristin Claflin

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$153,846

FY 2026

Project Title

Regulation of neuronal function by mitochondrial uncoupling

Grant Number:

5K01DK133667-04

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY / ABSTRACT Obesity is a major contributor to the epidemic of metabolic diseases including type II diabetes, hypertension, cardiovascular disease, and liver disease. Excess weight gain is the result of a chronic imbalance between caloric intake and energy expenditure, and while severa...

Research Terms

<21+ years old><AD4BP protein><ATP Synthesis><ATP Synthesis Pathway><Active Oxygen><Ad4-binding protein><Address><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Amphibia><Amphibians><Animals><Anorectic Drug><Anorectic agent><Anorectics><Anorexiant><Anorexic Drugs><Anorexient Agent><Anorexient Drug><Anorexigenic Drugs><Appetite Depressants><Appetite Suppressants><Appetite-Depressing Drugs><Appetite-Suppressant Drugs><Arcuate Nucleus><Attenuated><Autoregulation><BAT uncoupling protein><Biology><Body Weight><Body Weight decreased><Brain><Brain Nervous System><Brain region><Brown Adipose Tissue><Brown Fat><CNS Nervous System><Caloric Intake><Cardiovascular Diseases><Cell Body><Cell Respiration><Cells><Cellular Respiration><Central Nervous System><Chemicals><Chronic><Consumption><D-Glucose><Data><Data Set><Development><Development Plans><Dextrose><Eating><Educational workshop><Electron Microscopy><Encephalon><Energy Expenditure><Energy Intake><Energy Metabolism><Epidemic><FTZF1 protein><Fatty Tissue><Food Energy><Food Intake><Fushi tarazu factor homolog 1><Future><Gene Expression><GeneHomolog><Generations><Genetic><Glucose><H+ element><H2O2><Heat Production><Hepatic Disorder><Hibernating Gland><High Fat Diet><Homeostasis><Homolog><Homologous Gene><Homologue><Hydrogen Ions><Hydrogen Peroxide><Hydroperoxide><Hypertension><Hypothalamic structure><Hypothalamus><Infundibular Nucleus><Ingestion><Inner mitochondrial membrane><Intermediary Metabolism><Investigators><Iowa><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Knowledge><Liver diseases><Mammalia><Mammals><Maturity-Onset Diabetes Mellitus><Measures><Mentorship><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Mice><Mice Mammals><Mitochondria><Molecular><Murine><Mus><NASH><NIDDK><NIDDM><NR5A1 protein><National Institute of Diabetes and Digestive and Kidney Diseases><Nerve Cells><Nerve Unit><Neural Cell><Neuraxis><Neurocyte><Neurons><Neuropeptides><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Null Mouse><Nutrient><Obesity><Organelles><Overweight><Oxidative Stress><Oxygen Consumption><Oxygen Radicals><Pathogenesis><Physiologic><Physiological><Physiological Homeostasis><Population><Position><Positioning Attribute><Prevention><Pro-Oxidants><Production><Protons><Publications><Reactive Oxygen Species><Regulation><Research><Research Personnel><Researchers><Respiration><Role><SF 1><SF-1 transcription factor><SF1><Scientific Publication><Secure><Signal Pathway><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure of nucleus infundibularis hypothalami><Synaptosomes><T2 DM><T2D><T2DM><Testing><Therapeutic><Thermogenesis><Thesaurismosis><Training><Transcript><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Viral><Viral Vector><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Workshop><adipose><adiposity><adrenal 4 binding protein><adult onset diabetes><adulthood><aerobic metabolism><aerobic respiration><anorexic agent><attenuate><attenuates><body weight gain><body weight increase><body weight loss><brain control><brown adipose tissue uncoupling protein><caloric dietary content><cardiovascular disorder><career><career development><combat><conference><convention><corpulence><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><energy balance><excessive weight gain><experiment><experimental research><experimental study><experiments><extreme weight gain><hepatic disease><hepatopathy><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypothalamic><improved><in silico><ingest><insight><ketosis resistant diabetes><knock-down><knockdown><liver disorder><maturity onset diabetes><metabolism disorder><mitochondrial><mitochondrial dysfunction><mitochondrial membrane uncoupling protein><mitochondrial uncoupling protein><mouse model><murine model><neuronal><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><non-alcohol induced steatohepatitis><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><nuclear receptor 5A1 protein><obesity intervention><obesity management><obesity prevention><obesity therapy><obesity treatment><overexpress><overexpression><oxidative damage><oxidative injury><oxidative metabolism><pharmacologic><prevent obesity><respiratory mechanism><scRNA sequencing><scRNA-seq><serious weight gain><severe weight gain><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><steroid hormone receptor Ad4BP><steroidogenic factor 1><summit><symposia><symposium><synaptoneurosome><targeted agent><thermogenin><transcription factor sf1><type 2 DM><type II DM><type two diabetes><uncoupling protein 1><viral rescue><white adipose tissue><wt gain><wt-loss><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alessandro Bitto

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$146,750

FY 2026

Project Title

Activation of C/EBP-β by mitohormesis as a therapy for obesity

Grant Number:

5K01DK128128-05

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary It is estimated that around 40% of the adult population of the United States is obese and thus at increased risk for several chronic illnesses. Current weight loss strategies for obese people are often ineffective and come with serious neurological side effects. This proposal aims to...

Research Terms

<21+ years old><Active Oxygen><Adipocytes><Adipose Cell><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aging><Animals><Antioxidants><Architecture><Attenuated><Autoregulation><Basal Transcription Factor><Basal transcription factor genes><Big Data><BigData><Biochemical Pathway><Biological Aging><Biology><Biology of Aging><Body Tissues><Body Weight decreased><C-EBP Nuclear Protein><C-EBP Proteins><C/EBP><CAAT-Enhancer-Binding Proteins><CCAAT Sequence-Specific DNA-Binding Proteins><CCAAT-Enhancer-Binding Proteins><CSAID-Binding Protein 1><CSAID-Binding Protein 2><CSBP2><Caloric Restriction><Cancers><Cardiovascular Diseases><Catabolism><Chronic Disease><Chronic Illness><Cytokine-Suppressive Antiinflammatory Drug-Binding Protein 1><Cytokine-Suppressive Antiinflammatory Drug-Binding protein 2><DNA polymerase gamma><DNA polymerase γ><Data><Data Analyses><Data Analysis><Developed Countries><Diabetes Mellitus><Drugs><Endocrine><Energy Expenditure><Energy Metabolism><Engineering / Architecture><Extracellular Signal-Regulated Kinase Gene><FDA licensed drugs><FDA-approved agents><FDA-approved drug><FDA-approved medications><FDA-approved pharmaceuticals><FDA-approved therapeutic agent><FK506 Binding Protein 12-Rapamycin Associated Protein 1><FKBP12 Rapamycin Complex Associated Protein 1><FRAP1><FRAP1 gene><FRAP2><Fat Cells><Fats><Fatty Acid Metabolism Pathway><Fatty Tissue><Fatty acid glycerol esters><Food and Drug Administration approved drug><Food and Drug Administration approved medications><Food and Drug Administration approved pharmaceuticals><Gene Expression><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic><Geroscience><Glucose tolerance test><Health><Hepatic><Homeostasis><Hyperglycemia><IPGTT><In Vitro><Increase lifespan><Indirect Calorimetry><Industrialized Countries><Industrialized Nations><Institution><Insulin Resistance><Isoforms><Ketosis-Resistant Diabetes Mellitus><Knock-in><Knock-out><Knockout><Limulus factor C><Lipocytes><Liver><MAP Kinase Gene><MAPK><MAPK14><MAPK14 Mitogen-Activated Protein Kinase><MAPK14 gene><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Measures><Mechanistic Target of Rapamycin><Mediating><Medication><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Networks><Metabolic dysfunction><Metabolic syndrome><Mice><Mice Mammals><Mitochondria><Mitochondrial DNA><Mitogen-Activated Protein Kinase 14><Mitogen-Activated Protein Kinase Gene><Modeling><Morbid Obesity><Murine><Mus><Mxi2><NIDDM><Neurologic><Neurological><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrient><Obese Mice><Obesity><Oxygen Radicals><Pathogenesis><Pathology><Pathway interactions><Pharmaceutical Preparations><Phosphorylation><Physiological Homeostasis><Population><Pro-Oxidants><Process><Property><Protein Isoforms><Protein Phosphorylation><Proteins><RAFT1><Reactive Oxygen Species><Research><Respiration Calorimetry><Reverse Transcriptase Inhibitors><Risk><Risk Factors><Rodent><Rodentia><Rodents Mammals><Role><SAPK2A><Severe obesity><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stress><Stress-Activated Protein Kinase 2A><T2 DM><T2D><T2DM><Techniques><Testing><Thesaurismosis><Tissues><Training><Transcription Factor Proto-Oncogene><Transcription factor genes><Transgenic Model><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Viral><Weight><Weight Loss><Weight Reduction><adefovir depivoxil><adefovir dipivoxil><adipogenesis><adipose><adiposity><adult onset diabetes><adulthood><analytical tool><attenuate><attenuates><biological adaptation to stress><biological process of age><blood glucose regulation><body weight loss><boost longevity><calorie restriction><cardiovascular disorder><chronic disorder><constitutive expression><constitutive gene expression><corpulence><data interpretation><developed country><developed nation><developed nations><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><drug/agent><elongating the lifespan><energy balance><enhance longevity><experiment><experimental research><experimental study><experiments><extend life span><extend lifespan><extend longevity><extreme obesity><factor C><fat metabolism><fatty acid metabolism><fatty acid oxidation><foster longevity><geroscientific><glucose control><glucose homeostasis><glucose metabolism><glucose regulation><hepatic body system><hepatic metabolism><hepatic organ system><horseshoe crab factor C><hyperglycemic><improve lifespan><improve longevity><in vivo><insight><insulin resistant><insulin sensitivity test><insulin tolerance><insulin tolerance test><insulin-induced hypoglycemia test><intervention enhancing longevity><intervention to extend lifespan><intervention to improve lifespan><intervention to increase longevity><intervention to prolong lifespan><intervention to promote longevity><intraperitoneal glucose tolerance test><ketosis resistant diabetes><knockin><lifespan extending intervention><lifespan extending therapies><lifespan extension><lifespan improving intervention><lifespan increasing intervention><lifespan increasing therapies><lifespan intervention><lifespan prolonging interventions><lifespan promoting intervention><lipid biosynthesis><lipid metabolism><lipogenesis><liver metabolism><longevity boosting intervention><longevity extending intervention><longevity intervention><longevity promoting intervention><longevity therapy><longevity treatment><mTOR><malignancy><mammalian target of rapamycin><maturity onset diabetes><metabolic phenotype><metabolism disorder><metabotype><mitochondrial><mitochondrial dysfunction><mouse model><mtDNA><murine model><neoplasm/cancer><new approaches><novel><novel approaches><novel strategies><novel strategy><nucleoside analog><nutrient metabolism><ob/ob mouse><obese individuals><obese people><obese person><obese population><obese subjects><obesigenic><obesity intervention><obesity prevention><obesity therapy><obesity treatment><obesity-promoting diet><obesogenic><obesogenic Western-style diet><obesogenic diet><obesogenic high fat diet><obesogenic western diet><p38><p38 MAP Kinase><p38 MAPK Gene><p38 Mitogen Activated Protein Kinase><p38 Protein Kinase><p38 SAPK><p38-Alpha><p38Alpha><pathway><pharmacologic><prevent><prevent obesity><preventing><pro-obesity diet><programs><prolong lifespan><prolong longevity><promote lifespan><promote longevity><protein expression><reactioncrisis><response><side effect><social role><strategy to enhance longevity><strategy to promote longevity><stress activated protein kinase><stress response><stressreaction><stressor><support longevity><tissue culture><transcription factor><transgenic trait><translation><type 2 DM><type II DM><type two diabetes><weights><white adipose tissue><wt-loss><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ericka Nayram Merriwether

NEW YORK UNIVERSITY, NEW YORK, NY

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$142,767

FY 2026

Project Title

Determining Mechanisms of Pain Reduction in Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults

Grant Number:

5K23AR080846-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/28/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary/Abstract Chronic widespread pain (CWP) is a chronic pain subtype that affects multiple body sites, and is strongly associated with poor function and disability. Although CWP is highly prevalent in adults with obesity, CWP outcomes are disproportionately worse in non-Hispanic Black (N...

Research Terms

<21+ years old><Address><Adult><Adult Human><Affect><Age><Analgesia Tests><Anxiety><Behavioral><Black><Black race><Body Weight decreased><Classification><Clinical><Clinical Research><Clinical Study><Clinical Trials Design><Communities><Development Plans><Development and Research><Dimensions><Disparities><Disparity><Environment><Ethnic Origin><Ethnicity><Evaluation><Feasibility Studies><Fiber><Florida><Fostering><Foundations><Gender Identity><General Population><General Public><Goals><Health Disparities Research><Health disparities related research><Health equity research><Hispanic><Hospitals><Incubators><Institution><Joints><K23 Award><K23 Mechanism><K23 Program><Knowledge><Latina><Latine><Latino><Latinx><Latinx group><Latinx individual><Latinx people><Latinx population><Life Style><Lifestyle><Lower Extremity><Lower Limb><Maintenance><Measurement><Measures><Mechanics><Mediating><Mediation><Membrum inferius><Mental Depression><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Methodology><Methods><Modeling><Motion><Movement><Musculoskeletal><Musculoskeletal Pain><Negotiating><Negotiation><New York><Nociception><Nociception Tests><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Obesity><Pain><Pain Assessment><Pain Control><Pain Measurement><Pain Research><Pain Therapy><Pain Threshold><Pain Tolerance Level><Pain management><Pain measure><Painful><Participant><Patient Self-Report><Patients><Phenotype><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical therapy><Physiotherapy><Population><Population Heterogeneity><Psychosocial Factor><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Race><Races><Recurrence><Recurrent><Refractory><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Research Training><Research in health equity><Resolution><Resources><Rest><Self-Report><Sensory><Site><Sleep disturbances><Standardization><Statistical Methods><Stress><Systematics><Testing><Time><Training><Universities><Weight><Weight Loss><Weight Reduction><Weight maintenance regimen><Work><aberrant sleep><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><ages><bariatric surgery><biobehavior><biobehavioral><biopsychosocial><biosignature><body movement><body weight loss><career><career development><chronic pain><chronic widespread pain><co-morbid><co-morbidity><comorbidity><conditioned pain modulation><corpulence><demographics><depression><differences due to race><differences in race><differs by race><differs in race><disability><disparity in health><disrupted sleep><disturbed sleep><diverse populations><ethnic diversity><ethnically diverse><experience><fall risk><gastric banding><gastric bypass surgery><health disparities science><health disparity><health equity-focused research><heterogeneous population><impaired sleep><implantable gastric stimulation banding><improved><indexing><inhibit pain><innovate><innovation><innovative><irregular sleep><mechanic><mechanical><mechanical load><multi-modality><multimodality><nociceptive><obesity surgery><pain assay><pain inhibition><pain intervention><pain outcome><pain perception><pain reduction><pain sensitivity><pain tolerance><pain treatment><pain-related outcome><phenotypic data><population diversity><pressure><primary outcome><psychosocial><psychosocial variables><race based differences><race differences><race related differences><racial><racial background><racial difference><racial diversity><racial origin><racially different><racially diverse><recruit><reduce pain><rehab research><rehabilitation research><research and development><research on health equity><research related to health equity><research to attain health equity><resolutions><response><sleep disruption><sleep dysregulation><sleep/wake disruption><sleep/wake disturbance><statistic methods><stomach stapling><synergism><translational investigator><translational researcher><translational scientist><weight control><weight loss surgery><weight management><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Clinton Michael Hasenour

VANDERBILT UNIVERSITY, Nashville, TN

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$120,591

FY 2026

Project Title

In vivo hepato-renal metabolic flux dysregulation in obesity

Grant Number:

5K01DK135924-04

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary The liver and kidney are the major organs where glucose biosynthesis is coupled to mitochondrial metabolism. Previous studies demonstrate that overnutrition accelerates whole-body gluconeogenesis (GNG) and citric acid cycle (CAC) activity in vivo. A limitation of prior research is th...

Research Terms

<21+ years old><Abnormal Assessment of Metabolism><Acceleration><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Biologic Models><Biological Models><Body Tissues><Causality><Cell Respiration><Cellular Respiration><Chronic><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Citric Acid Cycle><Continuity of Care><Continuity of Patient Care><Continuum of Care><Coupled><D-Glucose><Data><Development><Development Plans><Dextrose><Diabetes Mellitus><Diabetic Kidney Disease><Diabetic Nephropathy><Dietary Intervention><Disease><Disease Progression><Disorder><Ensure><Etiology><Exhibits><Fats><Fatty Acids><Fatty Liver><Fatty acid glycerol esters><Foundations><Genetic><Gluconeogenesis><Glucose><Goals><Health><Hepatic><Human><Hypoglycemia><Impairment><Inflammation><Injury to Liver><Intermediary Metabolism><Intervention><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Knock-out><Knockout><Knowledge><Krebs Cycle><Link><Lipids><Liver><Liver Steatosis><Maturity-Onset Diabetes Mellitus><Mediating><Mentors><Metabolic><Metabolic Control><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolic Studies><Metabolic dysfunction><Metabolism><Metabolism Studies><Methods><Mice><Mice Mammals><Mitochondria><Model System><Modeling><Modern Man><Murine><Mus><NAFLD><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition Interventions><Nutritional Interventions><Obesity><Organ><Overnutrition><Oxidative Stress><Pathogenicity><Pathway interactions><Patient Care><Patient Care Delivery><Patients><Precision care><Predisposition><Prevalence><Proximal Kidney Tubules><Publishing><Regulation><Research><Research Infrastructure><Role><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Steatohepatitis><Stress><Susceptibility><T2 DM><T2D><T2DM><TCA cycle><Techniques><Testing><Therapeutic Intervention><Thesaurismosis><Time><Tissues><Training><Transgenic Mice><Tricarboxylic Acid Cycle><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Work><adiposity><adult onset diabetes><adulthood><aerobic metabolism><aerobic respiration><burden of disease><burden of illness><care for patients><care of patients><career><career development><caring for patients><causation><chronic kidney disease><clinical relevance><clinically relevant><corpulence><counterregulation><developmental><diabetes><diet intervention><dietary><disease burden><disease causation><euglycemia><glucose RA><glucose biosynthesis><glucose metabolism><glucose production><glucose rate of appearance><glycemic control><hepatic body system><hepatic damage><hepatic injury><hepatic metabolism><hepatic organ system><hepatic steatosis><hepatosteatosis><hypoglycemic><hypoglycemic episodes><improved><in vivo><individualized care><individualized patient care><inhibitor><injury to tissue><innovate><innovation><innovative><insight><intervention therapy><ketosis resistant diabetes><kidney metabolism><lens><lenses><liver damage><liver injury><liver metabolism><maturity onset diabetes><member><metabolic abnormality assessment><metabolism disorder><mitochondrial><mitochondrial dysfunction><mitochondrial metabolism><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><obesity development><oxidation><oxidative metabolism><pathway><personalized care><personalized patient care><preservation><renal><renal proximal tubule><social role><stable isotope><therapeutic target><tissue injury><type 2 DM><type II DM><type two diabetes><western diet><western-style diet><western-type diet>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marisa Stachowski

NORTHWESTERN UNIVERSITY AT CHICAGO, CHICAGO, IL

Good lead · 48/100

Training-friendly

Very recent

Active award

$80,224

FY 2026

Project Title

Cardiac regulation of heart failure and obesity

Grant Number:

5F32HL177905-02

Activity Code:

F32

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

2/1/2025

End Date:

1/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Heart failure impacts over 5 million Americans annually. Obesity increases risk factors associated with heart failure. The gene MTCH2 has genetic variants that associate with both cardiomyopathy and obesity. The human genetic data support that reduction of MTCH2 protein incr...

Research Terms

<ADD-1 protein><ADD1 protein><Abscission><Actin Filaments><Aging><Alleles><Allelomorphs><American><Apoptosis><Apoptosis Pathway><Autophagocytosis><BMI><BMI percentile><BMI z-score><Basal Transcription Factor><Basal transcription factor genes><Biology><Body Composition><Body Weight decreased><Body fat><Body mass index><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Muscle Cells><Cardiac Myocytes><Cardiocyte><Cardiomyopathies><Cell Body><Cells><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Cross-Product Ratio><DNA mutation><Data><Development><Diabetes Mellitus><Diet><Dysfunction><Dyslipidemias><Embryo><Embryonic><Energy Expenditure><Energy Metabolism><Epidemic><Excision><Extirpation><Fats><Fatty Acids><Fatty acid glycerol esters><Female><Fibroblasts><Functional disorder><Gene variant><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic><Genetic Change><Genetic defect><Genetic mutation><Goals><Heart><Heart Diseases><Heart Muscle Cells><Heart failure><Heart myocyte><Heterozygote><High Fat Diet><Human><Human Genetics><Hypertension><Hypertrophy><Impairment><Individual><Insulin Resistance><Intermediary Metabolism><Investigators><Isoprenaline><Isopropyl Noradrenaline><Isopropylarterenol><Isopropylnoradrenaline><Isopropylnorepinephrine><Isoproterenol><Isuprel><KO mice><Knock-out Mice><Knockout Mice><L-Proline><Link><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measures><Mediating><Mediator><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Metabolic><Metabolic Processes><Metabolism><Mice><Mice Mammals><Microfilaments><Mitochondria><Mitochondrial Membrane Protein><Mitochondrial Proteins><Modern Man><Murine><Mus><Mutation><Myocardial><Myocardial Diseases><Myocardial Disorder><Myocardial depression><Myocardial dysfunction><Myocardiopathies><Myofilaments><Null Mouse><Obesity><Odds Ratio><Outer Mitochondrial Membrane><Physiopathology><Position><Positioning Attribute><Production><Programmed Cell Death><Proline><Proteins><Proteome><Quetelet index><Regulation><Relative Odds><Removal><Research Personnel><Researchers><Risk><Risk Factors><Risk Ratio><Role><SRE-1 binding protein><SREBP-1><SREBP-1c><Sarcomeres><Sarcoplasmic Reticulum><Surface Proteins><Surgical Removal><Tail><Testing><Training><Transcription Activation><Transcription Factor Proto-Oncogene><Transcription factor genes><Transcriptional Activation><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Weight Loss><Weight Reduction><adiposity><allelic variant><atherosclerotic coronary disease><autophagy><biobank><biorepository><body weight loss><cardiac dysfunction><cardiac failure><cardiac function><cardiomyocyte><compare to control><comparison control><coronary arterial disease><corpulence><cost><developmental><diabetes><diets><function of the heart><genetic variant><genome mutation><genomic variant><heart disorder><heart dysfunction><heart function><heterozygosity><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><insulin resistant><insulin tolerance><male><mitochondrial><mitochondrial cardiomyopathies><mitochondrial dysfunction><mitochondrial metabolism><mouse model><murine model><myocardium disease><myocardium disorder><obesity risk><overexpress><overexpression><pathophysiology><protein function><resection><response><risk for obesity><risk of obesity><social role><sterol regulatory element binding protein-1c><sterol regulatory element-binding protein 1><stressor><transcription factor><transcription factor ADD1><wt-loss><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Silas A Culver

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$165,067

FY 2026

Project Title

Role of Atp6ap2 in renal proximal tubule lipotoxicity

Grant Number:

5K08DK132463-04

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary The rising rates of obesity worldwide contribute directly to an increased prevalence of chronic kidney disease. With current methods for mitigating obesity related kidney injury incompletely effective, novel approaches to this problem are needed. In renal lipotoxicity, toxic lipid m...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Samantha Fortin

UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, FARMINGTON, CT

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$150,930

FY 2026

Project Title

Examining the role of locus coeruleus glucagon-like peptide-1 receptors infeeding behavior.

Grant Number:

7K01DK133627-04

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/19/2025

End Date:

2/29/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary/Abstract The staggering prevalence of obesity presents major public health and economic consequences. Effective anti- obesity drugs are desperately needed to combat the obesity epidemic, as behavioral strategies offer limited success. Analogs of the endogenous satiety signal glucagon...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Folami Ideraabdullah

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$427,625

FY 2026

Project Title

Developmental windows of vitamin D supplementation for optimal metabolic health

Grant Number:

1R21AT012542-01A1

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2028

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT: Obesity is prevalent among adults (>40%) and children (~20%) in the U.S. and is expected to increase dramatically in the next 25 years. Addressing the obesity epidemic is vital for public health because of its wide range of comorbidities including deadly conditions such as stroke, hyperten...

Research Terms

<0-11 years old><1st trimester><21+ years old><2nd trimester><Acids><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adverse Experience><Adverse event><Alanine><Amino Acids><Animals><Apoplexy><Attention><Automobile Driving><Autoregulation><Bacteria><Biology><Biota><Birth><Body System><Brain Vascular Accident><Caloric Intake><Cancers><Cardiac Diseases><Cardiac Disorders><Cells Placenta-Tissue><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chemicals><Child><Child Youth><Children (0-21)><Chronic><Chronic Disease><Chronic Illness><Clinical Treatment><Colonic Diseases><Colony-forming units><Conceptions><DNA mutation><Data><Defect><Development><Diabetes Mellitus><Diathesis><Dietary Component><Disease susceptibility><Dysfunction><E coli><E. coli><Early Placental Phase><Embryo><Embryonic><Energy Intake><Energy Metabolism - Reference Pathway><Energy Metabolism Pathway><Environment><Epidemic><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Escherichia coli><Ethics><Event><Experimental Models><Exposure to><Fatty Liver><Female><Fetal Liver><Fetal Tissues><Fetus><First Pregnancy Trimester><First Trimester><Functional disorder><GI microbiota><Gastrointestinal microbiota><Gene Transcription><Genes><Genetic><Genetic Change><Genetic Transcription><Genetic defect><Genetic mutation><Germ-Free><Gestation><Health><Heart Diseases><Hepatic Disorder><Hexose Monophosphate Shunt><Homeostasis><Hour><Human><Hygiene><Hyperlipemia><Hyperlipidemia><Hypertension><Immune><Immune system><Immunes><Immunology><Impairment><Individual><Intermediary Metabolism><Intervention><Intestinal><Intestines><Laboratories><Lactation><Life><Link><Liver><Liver Steatosis><Liver diseases><Malignant Neoplasms><Malignant Tumor><Maps><Maternal Nutrition><Maternal diet><Metabolic><Metabolic Processes><Metabolic dysfunction><Metabolism><Mice><Mice Mammals><Midtrimester><Milk><Modeling><Modern Man><Molecular><Monitor><Mothers><Murine><Mus><Mutation><NAFLD><Nature><Normal Placentoma><Nutrient><Nutrition><Obesity><Obesity Epidemic><Oocytes><Oral><Organ><Organ System><Organism><Ovocytes><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><Parturition><Pathway interactions><Pentose Phosphate Pathway><Pentose Phosphate Shunt><Pentose Shunt><Pentosephosphate Pathway><Pentosephosphate Shunt><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phenotype><Physiological Homeostasis><Physiopathology><Placenta><Placenta Embryonic Tissue><Placentome><Plants><Play><Population><Predisposition><Pregnancy><Pregnancy Complications><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Preventative measure><Preventive><Preventive measure><Public Health><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Recommendation><Research><Risk><Rodent><Rodent Model><Rodentia><Rodents Mammals><Role><Second Pregnancy Trimester><Second Trimester><Shapes><Sleep Apnea><Sleep Apnea Syndromes><Sleep Hypopnea><Sleep-Disordered Breathing><Source><Stroke><Study models><Supplementation><Supplementation with vitamin D><Susceptibility><System><Testing><Time><Transcription><Transcriptional Control><Transcriptional Regulation><United States><Uterus><VIT D><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vitamin D><Vitamin D Deficiency><Vitamin D supplementation><Weaning><Work><Xenobiotics><absorption><adiposity><adulthood><aged><aminoacid><before conception><bowel><brain attack><caloric dietary content><candidate biomarker><candidate marker><cerebral vascular accident><cerebrovascular accident><child adiposity><child obesity><childhood adiposity><childhood obesity><cholesterol biosynthesis><chronic disorder><clinical intervention><clinical therapy><co-morbid><co-morbidity><colon disorder><commensal bacteria><commensal bacterial species><comorbidity><complications during pregnancy><corpulence><developmental><diabetes><disease risk><disorder risk><driving><effective intervention><enteric microbial community><enteric microbiota><epigenetically><ethical><expectant mother><expectant women><expecting mother><expecting women><experiment><experimental research><experimental study><experiments><fetal><fetus tissue><gastrointestinal microbial flora><genome mutation><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiota><gut microbiotic><gut microflora><heart disorder><hepatic body system><hepatic disease><hepatic organ system><hepatic steatosis><hepatopathy><hepatosteatosis><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><individuals who are pregnant><intestinal flora><intestinal microbiota><intestinal microflora><intestinal tract microflora><intrauterine infection><juvenile><juvenile human><kids><lactating><lactational><later in life><later life><liability to disease><life span><lifespan><liver development><liver disorder><living system><malignancy><maternal GI tract><maternal flora><maternal gut><maternal microbiota><maternal nutrition during pregnancy><member><metabolic phenotype><metabotype><microbial><microbial consortia><microbial flora><microbiota><microflora><micronutrient deficiency><microorganism><mother nutrition><mother's gut><mouse model><multispecies consortia><murine model><mutant><neonatal immune system><neoplasm/cancer><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><obese children><obesigenic><obesity during childhood><obesity in children><obesity intervention><obesity risk><obesity therapy><obesity treatment><obesogenic><offspring><pathogen><pathophysiology><pathway><pediatric obesity><people who are pregnant><perinatal development><pharmaceutical><post-natal period><postnatal><postnatal period><preconception><pregnancy-related complications><pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><preterm delivery><prior to conception><pup><risk for obesity><risk of obesity><sleep-related breathing disorder><social role><stillbirth><stillborn><stroked><strokes><those who are pregnant><time use><transcriptome sequencing><transcriptomic sequencing><trial regimen><trial treatment><vitamin D supplement><womb><women who are pregnant><youngster><♀>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Emma Wabel

HENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, EAST LANSING, MI

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$44,254

FY 2026

Project Title

Role of Vascular Chemerin as a Regulator of Blood Pressure and Contributor to Cardiovascular Disease

Grant Number:

5F31HL173985-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY: Increasing prevalence and regressing control of the common comorbidities obesity and hypertension pose a growing threat to human health, but targeted therapies specific to obesity-associated hypertension (65-78% of primary hypertension cases) are not yet developed. Aortic stiffness...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Taylor Coughlin

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$42,479

FY 2026

Project Title

Characterization of Nrac, a Novel Cardiac and Adipose Enriched Microprotein

Grant Number:

5F31HL178081-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/22/2024

End Date:

12/21/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Obesity is a widespread health concern impacting millions of individuals and is strongly associated with increased risk of cardiovascular disease (CVD). Despite advancements in understanding the metabolic implications of obesity, the connection between lipid droplet (LD) dynamics and...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marcos J Sanchez-Navarro

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$37,348

FY 2026

Project Title

The role of LDTg to VTA calcitonin receptor signaling in the control of food reward

Grant Number:

5F31DK139757-03

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary: Amylin signaling decreases food intake and gastric emptying in both humans and rats via activation of CNS amylin receptors (calcitonin receptor, CTR; heterodimerized with a receptor activating modified protein, RAMP1-3) making it a potential target for the development of novel pharm...

Research Terms

<21+ years old><Adult><Adult Human><Affect><Anatomic Sites><Anatomic structures><Anatomy><Animal Feed><Animals><Anorectic Drug><Anorectic agent><Anorectics><Anorexiant><Anorexic Drugs><Anorexient Agent><Anorexient Drug><Anorexigenic Drugs><Appetite Depressants><Appetite Suppressants><Appetite-Depressing Drugs><Appetite-Suppressant Drugs><Assay><Behavior><Binding><Bioassay><Biological Assay><Body Weight><Body Weight Changes><Calcitonin><Calcitonin Receptor><Calcitrin><Caloric Intake><Cardiovascular Diseases><Cell Communication and Signaling><Cell Nucleus><Cell Signaling><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Common Rat Strains><DA Neuron><DREADDs><Data><Development><Diet><Disturbance in cognition><Dopamine><Dopamine neuron><Drug Therapy><Eating><Endocrine Gland Secretion><Energy Intake><Energy consumption><Feeding behaviors><Female><Fiber><Food><Food Intake><Food Intake Regulation><Gastric Emptying><Genetic><Heterodimerization><High Fat Diet><Hind Brain><Hormones><Human><Hydroxytyramine><Hypothalamic structure><Hypothalamus><IAPP receptor><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Impaired cognition><Impairment><Impulsivity><Ingestive Behavior><Insulinoma amyloid peptide><Intake><Intracellular Communication and Signaling><Knowledge><Leanness><Malaise><Mediating><Metabolic><Modern Man><Molecular Interaction><Monitor><Motivation><Nature><Nerve Cells><Nerve Unit><Neural Cell><Neural Transmission><Neurocyte><Neuroendocrine><Neuroendocrine System><Neurons><Neurosecretory Systems><Nucleus><Nutrient><Obesity><Overweight><Pathway interactions><Pattern><Pharmacological Treatment><Pharmacotherapy><Photometry><Physiologic><Physiological><Proteins><Public Health><RAMP1><Rat><Rats Mammals><Rattus><Receptor Protein><Receptor Signaling><Regulation><Research><Rewards><Rhombencephalon><Rodent><Rodentia><Rodents Mammals><Role><Salmon><Satiation><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Structure><Symptoms><Synaptic Transmission><System><Testing><Therapeutic Hormone><Thinness><Thyrocalcitonin><United States><Ventral Tegmental Area><Viral><Viral Vector><Weight Change><Weight Gain><Weight Increase><Work><adiposity><adulthood><amlintide><amylin><amylin receptor><analog><animal food><anorexic agent><biological signal transduction><body weight gain><body weight increase><caloric dietary content><cardiovascular disorder><co-morbid><co-morbidity><cognitive dysfunction><cognitive loss><combat><comorbidity><corpulence><designer receptors exclusively activated by designer drugs><developmental><diabetes associated peptide><diabetes risk><diet-associated obesity><diet-induced obesity><diet-related obesity><diets><dopaminergic neuron><drug intervention><drug treatment><eat less><energy balance><experiment><experimental research><experimental study><experiments><feeding><feeding-related behaviors><gastrointestinal><hindbrain><hypothalamic><in vivo><insulinoma amyloid polypeptide><islet amyloid polypeptide><islet amyloid polypeptide receptor><knock-down><knockdown><male><motivated behavior><neuronal><novel><nutrient intake activity><obesity intervention><obesity therapy><obesity treatment><pancreatic amylin><pathway><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><receptor><reduced eating><reduced food intake><response><satiety><social role><stomach emptying><ventral tegmentum><western diet><western-style diet><western-type diet><wt gain><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Maci Winn

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 34/100

Training-friendly

Active award

$55,114

FY 2026

Project Title

Metabolic Obesity Phenotypes and Obesity-related Cancer Survival

Grant Number:

5F30CA278348-03

Activity Code:

F30

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY. The incidence of obesity-related cancer (ORC) continues to increase rapidly despite a decrease in overall cancer incidence; currently ORCs constitute over 40% of all cancers making them a significant public health concern. Strong evidence suggests that both obesity and metabolic dys...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Claire Chaikin

NORTHWESTERN UNIVERSITY AT CHICAGO, CHICAGO, IL

Exploratory lead · 34/100

Training-friendly

Active award

$44,835

FY 2026

Project Title

Circadian Clock Regulation of HIF1a-dependent Skeletal Muscle Metabolism during Diet-induced Obesity

Grant Number:

5F31DK139621-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary The mammalian circadian clock is comprised of an autoregulatory transcription-translation feedback loop expressed in the brain and peripheral tissues that coordinates metabolism with the sleep-wake cycle. Epidemiological and genetic studies have shown that disruption of circadian rhy...

Research Terms

<2-Deoxy-D-glucose><2-Deoxyglucose><2-Desoxy-D-glucose><2-deoxy-D-arabino-hexose><21+ years old><ARNTL><ARNTL gene><Acceleration><Adult><Adult Human><Amino Acids><Animals><Area><Automobile Driving><BMAL1><Basal Transcription Factor><Basal transcription factor genes><Behavior><Binding><Biological><Body Tissues><Brain><Brain Nervous System><CUT&RUN><Circadian Dysregulation><Circadian Rhythms><Cleavage Targets and Release Using Nuclease><Cleavage Under Targets and Release Using Nuclease><Data><Deoxyglucose><Development><Dysfunction><Embryonic Muscle Cells><Encephalon><Environment><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Feedback><Fiber><Functional disorder><Gastrocnemius Muscle><Gene Expression><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic><Genetic Transcription><Genetic study><Genomics><Genotype><Glucose Clamp><Glucose Intolerance><Glucose tolerance test><Glycolysis><Grip strength><HIF 1 alpha><HIF-1alpha><HIF1-Alpha><HIF1A><HIF1A gene><HIF1α><Hand Strength><High Fat Diet><Humulin R><Hyperglycemia><Hyperinsulinemic Clamp><Hypoxia><Hypoxia Inducible Factor><Hypoxia-Inducible Factor Pathway><Hypoxia-Inducible Factor in the Cardiovascular System><Hypoxic><IPGTT><Impairment><In Vitro><Insulin><Insulin Resistance><Intermediary Metabolism><Knock-out><Knockout><Lead><Leanness><Life><Link><Location><MOP1><Maintenance><Measurement><Mediating><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolic syndrome><Metabolism><Methods><Mice><Mice Mammals><Mitochondria><Modeling><Modernization><Molecular Interaction><Murine><Mus><Muscle><Muscle Atrophy><Muscle Tissue><Muscle function><Muscular Atrophy><Myoblasts><Novolin R><Nutrient><Nyctohemeral Rhythm><Obesity><Organism><Oxygen Deficiency><Pathway interactions><Pb element><Peripheral><Phenotype><Physiology><Physiopathology><Precursor Muscle Cells><Prevention><Process><Protein Biosynthesis><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Regulation><Respiration><Ribosomal Peptide Biosynthesis><Ribosomal Protein Biosynthesis><Ribosomal Protein Synthesis><Role><Signal Pathway><Skeletal Muscle><Sleep Wake Cycle><Societies><Stress><Symptoms><Testing><Thesaurismosis><Thinness><Tissues><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Transcriptional Control><Transcriptional Regulation><Translations><Twenty-Four Hour Rhythm><Voluntary Muscle><Weight><Work><adiposity><adulthood><aminoacid><aryl hydrocarbon receptor nuclear translocator-like><biologic><blood glucose regulation><circadian abnormality><circadian clock><circadian disruption><circadian disturbance><circadian dysfunction><circadian impairment><circadian pacemaker><circadian process><circadian rhythmicity><compare to control><comparison control><corpulence><daily biorhythm><decreased muscle mass><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><driving><epidemiology research study><epidemiology study><epidemiology survey><experiment><experimental research><experimental study><experiments><gastrocnemius><glucose control><glucose homeostasis><glucose metabolism><glucose regulation><glucose tolerance><glucose uptake><heavy metal Pb><heavy metal lead><hyperglycemic><impaired glucose tolerance><improved><in vivo><insight><insulin resistant><insulin signaling><insulin tolerance><interest><intraperitoneal glucose tolerance test><living system><low muscle mass><metabolic rate><metabolism disorder><metabolism measurement><metabolomics><metabonomics><mitochondrial><molecular clock><muscle breakdown><muscle bulk><muscle degradation><muscle deterioration><muscle form><muscle loss><muscle mass><muscle metabolism><muscle structure><muscle wasting><muscular><muscular structure><mutant><pathophysiology><pathway><protein synthesis><reduced muscle mass><respiratory mechanism><response><sarcopenia><sarcopenic><skeletal muscle metabolism><skeletal muscle protein metabolism><sleep to wake transition><sleep to wakefulness transition><sleep wakefulness cycle><sleep/wake transitions><social role><transcription factor><transcriptome sequencing><transcriptomic sequencing><translation><uptake><weights>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kathryn M Brewer

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Exploratory lead · 34/100

Training-friendly

Active award

$40,858

FY 2026

Project Title

Cilia-mediated Proliferation in Hypothalamic Tanycytes

Grant Number:

5F31DK142351-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/17/2024

End Date:

12/16/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Obesity promotes heart disease and diabetes; both causes of early mortality. Most adults in the United States are overweight, and obesity adds cost to healthcare. Mechanisms regulating energy homeostasis are not completely understood. Recently, small cell appendages in the brain call...

Research Terms

<21+ years old><Adult><Adult Human><Alleles><Allelomorphs><Architecture><Assay><Autoregulation><BUdR><Bioassay><Biological Assay><Body Composition><Body Tissues><Body Weight><Brain><Brain Nervous System><Brain region><BrdU><Bromodeoxyuridine><Bromouracil Deoxyriboside><Broxuridine><Caloric Restriction><Cardiac Diseases><Cardiac Disorders><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Growth in Number><Cell Interaction><Cell Multiplication><Cell Proliferation><Cell Signaling><Cell-to-Cell Interaction><Cells><Cellular Proliferation><Cerebrospinal Fluid><Chronic><Cilia><Clinical><Computer Assisted><Confocal Microscopy><Data><Development><Diabetes Mellitus><Disease><Disorder><Embryo Development><Embryogenesis><Embryonic Development><Encephalon><Engineering / Architecture><Erinaceidae><Fasting><Feeding behaviors><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G-Protein-Coupled Receptors><GPCR><Genetic><Health><Health Care><Heart Diseases><Hedgehog (Hh) signal transduction pathway><Hedgehogs><High Fat Diet><Homeostasis><Hyperphagia><Hypothalamic structure><Hypothalamus><Immunofluorescence><Immunofluorescence Immunologic><In Vitro><Ingestive Behavior><Intracellular Communication and Signaling><Ligands><Measures><Mediating><Mediator><Metabolic><Mice><Mice Mammals><Murine><Mus><Obesity><Overeating><Overweight><Pathway interactions><Pattern><Physiologic><Physiological><Physiological Homeostasis><Population><Position><Positioning Attribute><Process><Proliferating><Proteins><Regulation><Reporter><Repression><Role><Sensory><Signal Induction><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Testing><Therapeutic><Third Cerebral Ventricle><Third Ventricle><Third ventricle structure><Tissues><Training><United States><Ventricular><adiposity><adulthood><appendage><biological signal transduction><calorie restriction><cell type><cerebral spinal fluid><computer aided><conditional mutant><conditional mutation><corpulence><cost><developmental><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><embryo cell><experiment><experimental research><experimental study><experiments><fasted><fasts><feeding><feeding-related behaviors><heart disorder><hedgehog signaling><hedgehog signaling pathway><hh signaling pathway><hypothalamic><in vivo><induced Cre><inducible Cre><insight><migration><mortality><mouse model><murine model><nerve cell death><nerve cell loss><neuron cell death><neuron cell loss><neuron death><neuron loss><neuronal cell death><neuronal cell loss><neuronal death><neuronal loss><nutrient intake activity><pathway><polyphagia><post-natal development><postnatal><postnatal development><precursor cell><prevent><preventing><progenitor cell proliferation><progenitor proliferation><response><smoothened signaling pathway><social role><spinal fluid><stem and progenitor cell proliferation><stem cell proliferation><subventricular zone><third brain ventricle>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Tina E Brinkley

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

Exploratory lead · 32/100

Solid budget

Recent

Active award

$426,250

FY 2026

Project Title

Vibegron: A Novel Treatment for Multisystem Functional Decline in Aging and Obesity

Grant Number:

1R21AG091075-01A1

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2026

End Date:

1/31/2028

Project Abstract

PROJECT SUMMARY Aging is characterized by the gradual loss of physiological integrity, and this process may be accelerated in the presence of obesity, increasing susceptibility to disease, frailty, and death. Although the shared molecular pathways involved have not been fully elucidated, adipose tis...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ELIZABETH Ann LEADBETTER

UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, SAN ANTONIO, TX

Exploratory lead · 32/100

Solid budget

Recent

Active award

$421,223

FY 2026

Project Title

Dissecting the role of CD36 on Tbet+ B cells during obesity and autoimmunity

Grant Number:

1R21AI196999-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/5/2026

End Date:

1/31/2028

Project Abstract

CD21-CD23- CD11c+ Tbet+ Age Associated B Cells or ABCs, expand in primary immune and peripheral tissues during chronic conditions such as aging, autoimmune diseases, atherosclerosis, and obesity. These ABCs largely produce IgG2a/c autoantibodies which exacerbate autoimmunity and metabolic dysfunctio...

Research Terms

<2019 novel corona virus><2019 novel coronavirus><2019-nCoV><ASCVD><Aging><Agonist><Amyloid Proteins><Antigens><Apoptotic><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Autoantibodies><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Automobile Driving><B-Cell Subsets><B-Cells><B-Lymphocyte Subsets><B-Lymphocytes><B-cell><Binding><Body Tissues><C3d Receptors><CD 21 Antigens><CD11c><CD19><CD19 gene><CD21><CD21 Antigens><CD36><CD36 gene><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><COVID-19 virus><COVID19 virus><CR2><CR2 Receptors><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Metabolic Process><Cellular Physiology><Cellular Process><Chronic><Clinical Treatment><CoV-2><CoV2><Communicable Diseases><Complement 3d Receptors><Complement Receptors 2><Disease><Disorder><Elderly><Engineering><Epstein-Barr Virus Receptors><Equilibrium><Fatty Acids><Future><GP3B><GP4><GPIV><Germinal Center><Glycolysis><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><IL21><ITGAX><ITGAX gene><Immune><Immune Cell Activation><Immune response><Immunes><Impairment><In Vitro><Inducer Cells><Inducer T-Lymphocytes><Infection><Infectious Diseases><Infectious Disorder><Inflammation><Inflammatory><Influenza Virus><Intracellular Communication and Signaling><Lipids><Lupus><Lupus Erythematosus Disseminatus><Maintenance><Mediating><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Mice><Mice Mammals><Mitochondria><Modeling><Molecular><Molecular Interaction><Mouse Strains><Murine><Mus><Nature><Obesity><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><PPAR-beta><PPAR-β><PPARbeta><PPARβ><Pathologic><Pathology><Pathway interactions><Pattern><Peripheral><Phosphatides><Phospholipids><Position><Positioning Attribute><Regulation><Reporter><Role><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><SCARB3><SLE><SR-B proteins><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Signal Transduction><Signal Transduction Systems><Signaling><Sorting><Stimulus><Structure of germinal center of lymph node><Subcellular Process><Surface><Symptoms><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><T4 Cells><T4 Lymphocytes><TLR7><TLR7 gene><Testing><Thesaurismosis><Tissues><Toll-Like Receptor 7><Vaccines><Wuhan coronavirus><acetyl-LDL receptor><acetylated LDL receptor><adiposity><advanced age><age associated><age correlated><age dependent><age linked><age related><age specific><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><autoimmune antibody><autoimmune condition><autoimmune disorder><autoimmunity disease><autoreactive antibody><balance><balance function><biological signal transduction><cell metabolism><cellular metabaolism><chronic inflammatory disease><class B scavenger receptors><clinical intervention><clinical therapy><coronavirus disease 2019 virus><coronavirus disease-19 virus><corpulence><cytokine><design><designing><disseminated lupus erythematosus><driving><geriatric><hCoV19><host response><immune activation><immune response to vaccination><immune response to vaccines><immune system response><immunogen><immunoresponse><improved><in vivo><influenzavirus><interleukin-21><long chain fatty acid><metabolism disorder><mitochondrial><mouse model><murine model><nCoV2><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><obese patients><outcome following vaccination><outcome following vaccine><oxidized lipid><pathway><patients with obesity><response><result following vaccination><result following vaccine><scavenger receptor><self reactive antibody><senior citizen><social role><systemic lupus erythematosis><therapeutic target><translocase><trial regimen><trial treatment><uptake><vaccination outcome><vaccination result><vaccine associated immune response><vaccine immune response><vaccine immunogenicity><vaccine induced immune response><vaccine outcome><vaccine response><vaccine responsiveness><vaccine result><vaccine-induced response>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jatin Roper

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 32/100

Solid budget

Recent

Active award

$368,288

FY 2026

Project Title

Wnt signaling in obesity-associated colorectal cancer

Grant Number:

5R37CA259363-05

Activity Code:

R37

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/23/2022

End Date:

2/28/2027

Project Abstract

Project Summary Obesity affects 42% of the U.S. population and is a major risk factor for the development of colorectal cancer. Obese colorectal cancer patients have a five-fold increased risk of death compared to normal weight counterparts. However, the mechanisms by which obesity increases colorec...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ramiah Donesha Jacks

OHIO STATE UNIVERSITY, Columbus, OH

Exploratory lead · 30/100

Very recent

Active award

$249,001

FY 2026

Project Title

Regulation and Maintenance of Adipose Tissue T cells

Grant Number:

4R00DK136934-03

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2029

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Adipose tissue (AT) is an active metabolic organ that contains a network of immune cells whose crosstalk regulates adipose tissue homeostasis. In response to obesity, these immune cells can become activated, expand, and secrete adipokines and pro-inflammatory cytokines that modify local and systemic...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Wagner Silva Dantas

UNIVERSITY OF OREGON, EUGENE, OR

Exploratory lead · 30/100

Very recent

Active award

$249,000

FY 2026

Project Title

The Role of Nuclear Factor Erythroid 2-related factor 2 in Sarcopenic Obesity

Grant Number:

5R00AG083239-03

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Sarcopenic obesity is a debilitating condition that increases the risk of frailty, loss of autonomy, institutionalization, and death in older adults. Currently, obesity medications and lifestyle/behavioral interventions have limited efficacy for sarcopenia, worsening quality...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Roger D. Cone

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 30/100

Very recent

Active award

$231,000

FY 2026

Project Title

Remote Loading of Melanocortin and GLP-1 Peptides in Polymers for Treatment of Obesity

Grant Number:

1R56DK141545-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/17/2026

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Rates of obesity have steadily increased in the US, with about 50% of Americans projected to be obese by 2030. Recent advances include GLP-1 peptides, such as semaglutide, approved in 2021 for adult obesity, and setmelanotide, approved in 2020 for early-onset syndromic obesity due to POMC a...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

STEVEN P. SCHWENDEMAN

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 30/100

Very recent

Active award

$231,000

FY 2026

Project Title

Remote Loading of Melanocortin and GLP-1 Peptides in Polymers for Treatment of Obesity

Grant Number:

1R56DK141545-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/17/2026

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT Rates of obesity have steadily increased in the US, with about 50% of Americans projected to be obese by 2030. Recent advances include GLP-1 peptides, such as semaglutide, approved in 2021 for adult obesity, and setmelanotide, approved in 2020 for early-onset syndromic obesity due to POMC a...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LISA M COUSSENS

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Exploratory lead · 30/100

Very recent

Active award

$195,000

FY 2026

Project Title

Immunometabolic dysregulations in the offspring of obese mothers

Grant Number:

5R21HD118370-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2025

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Three out of ten women in the US are obese prior to becoming pregnant. Obese pregnant women face increased risk of obesity and metabolic disease in their newborns, thus initiating a vicious trajectory of obesity and its health-related consequences in subsequent generations, a phenomenon called devel...

Research Terms

<0-4 weeks old><21+ years old><Acetylsalicylic Acid><Adult><Adult Children><Adult Daughters><Adult Human><Adult Offspring><Adult Sons><Affect><Age><Aging><Amino Acids><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Aspirin><Asthma><B-Cells><B-Lymphocytes><B-cell><Bone Marrow><Bone Marrow Blood-Deriving Cell><Bone Marrow Blood-Forming Cell><Bone Marrow Cell Transplantation><Bone Marrow Cells><Bone Marrow Reticuloendothelial System><Bronchial Asthma><CD11b><CD19><CD19 gene><COX-2><COX2><CR3A><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular Diseases><Cell Body><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cells><Cells Placenta-Tissue><Chronic><Clinical Data><Data><Development><Diet><Disease><Disorder><Dose><Drugs><EPH Gestosis><Eating><Exposure to><Face><Fetus><Food Intake><Generations><Gestation><Glucose Intolerance><Glycolysis><Health><High Fat Diet><Human><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><IMiD><ITGAM><ITGAM gene><Immune><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Interferon><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune modulatory therapeutic><Immune system><Immunes><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunology><Individual><Inflammation><Inflammatory><Interferon Gamma><Interferon Type II><Life><Life Style><Lifestyle><Link><MAC1A><MO1A><Macrophage><Mediating><Medication><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Mice><Mice Mammals><Modeling><Modern Man><Mothers><Murine><Mus><Myeloid Cells><Mφ><Newborn Infant><Newborns><Normal Placentoma><Obesity><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><PGHS-2><PHS-2><PTGS2><PTGS2 gene><Pathologic><Pharmaceutical Preparations><Placenta><Placenta Embryonic Tissue><Placentome><Population><Position><Positioning Attribute><Pre-Eclampsia><Preeclampsia><Pregnancy><Pregnancy Toxemias><Pregnant Women><Production><Proteinuria-Edema-Hypertension Gestosis><Public Health><Reporting><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><Risk><Testing><Thesaurismosis><Weaning><Woman><adiposity><adulthood><adverse consequence><adverse outcome><ages><aminoacid><cardiometabolic><cardiometabolism><cardiovascular disorder><cell sorting><corpulence><developmental><diets><drug/agent><epidemiology research study><epidemiology study><epidemiology survey><expectant mother><expectant women><expecting mother><expecting women><faces><facial><fetal><hCOX-2><immune modulating agents><immune modulating drug><immune modulating therapeutics><immune modulatory agents><immune modulatory drugs><immunomodulating agents><immunomodulating drugs><immunomodulator agent><immunomodulator drug><immunomodulator medication><immunomodulator prodrug><immunomodulator therapeutic><immunomodulatory agents><immunomodulatory drugs><immunomodulatory therapeutics><individuals who are pregnant><inflammation in mothers><intrauterine environment><intrauterine milieu><lFN-Gamma><later in life><later life><maternal adiposity><maternal inflammation><maternal obesity><metabolism disorder><metabolism measurement><metabolomics><metabonomics><mother inflammation><mouse model><multidisciplinary><murine model><newborn child><newborn children><obese mothers><obesity risk><offspring><people who are pregnant><pre-clinical trial><pre-eclamptic><preclinical trial><pregnancy toxemia/hypertension><pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><programs><respiratory><risk for obesity><risk of obesity><sex><systemic inflammation><systemic inflammatory response><therapeutic target><those who are pregnant><women who are pregnant>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alina Maloyan

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Exploratory lead · 30/100

Very recent

Active award

$195,000

FY 2026

Project Title

Immunometabolic dysregulations in the offspring of obese mothers

Grant Number:

5R21HD118370-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2025

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Three out of ten women in the US are obese prior to becoming pregnant. Obese pregnant women face increased risk of obesity and metabolic disease in their newborns, thus initiating a vicious trajectory of obesity and its health-related consequences in subsequent generations, a phenomenon called devel...

Research Terms

<0-4 weeks old><21+ years old><Acetylsalicylic Acid><Adult><Adult Children><Adult Daughters><Adult Human><Adult Offspring><Adult Sons><Affect><Age><Aging><Amino Acids><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Aspirin><Asthma><B-Cells><B-Lymphocytes><B-cell><Bone Marrow><Bone Marrow Blood-Deriving Cell><Bone Marrow Blood-Forming Cell><Bone Marrow Cell Transplantation><Bone Marrow Cells><Bone Marrow Reticuloendothelial System><Bronchial Asthma><CD11b><CD19><CD19 gene><COX-2><COX2><CR3A><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular Diseases><Cell Body><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cells><Cells Placenta-Tissue><Chronic><Clinical Data><Data><Development><Diet><Disease><Disorder><Dose><Drugs><EPH Gestosis><Eating><Exposure to><Face><Fetus><Food Intake><Generations><Gestation><Glucose Intolerance><Glycolysis><Health><High Fat Diet><Human><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><IMiD><ITGAM><ITGAM gene><Immune><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Interferon><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune modulatory therapeutic><Immune system><Immunes><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunology><Individual><Inflammation><Inflammatory><Interferon Gamma><Interferon Type II><Life><Life Style><Lifestyle><Link><MAC1A><MO1A><Macrophage><Mediating><Medication><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Mice><Mice Mammals><Modeling><Modern Man><Mothers><Murine><Mus><Myeloid Cells><Mφ><Newborn Infant><Newborns><Normal Placentoma><Obesity><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><PGHS-2><PHS-2><PTGS2><PTGS2 gene><Pathologic><Pharmaceutical Preparations><Placenta><Placenta Embryonic Tissue><Placentome><Population><Position><Positioning Attribute><Pre-Eclampsia><Preeclampsia><Pregnancy><Pregnancy Toxemias><Pregnant Women><Production><Proteinuria-Edema-Hypertension Gestosis><Public Health><Reporting><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><Risk><Testing><Thesaurismosis><Weaning><Woman><adiposity><adulthood><adverse consequence><adverse outcome><ages><aminoacid><cardiometabolic><cardiometabolism><cardiovascular disorder><cell sorting><corpulence><developmental><diets><drug/agent><epidemiology research study><epidemiology study><epidemiology survey><expectant mother><expectant women><expecting mother><expecting women><faces><facial><fetal><hCOX-2><immune modulating agents><immune modulating drug><immune modulating therapeutics><immune modulatory agents><immune modulatory drugs><immunomodulating agents><immunomodulating drugs><immunomodulator agent><immunomodulator drug><immunomodulator medication><immunomodulator prodrug><immunomodulator therapeutic><immunomodulatory agents><immunomodulatory drugs><immunomodulatory therapeutics><individuals who are pregnant><inflammation in mothers><intrauterine environment><intrauterine milieu><lFN-Gamma><later in life><later life><maternal adiposity><maternal inflammation><maternal obesity><metabolism disorder><metabolism measurement><metabolomics><metabonomics><mother inflammation><mouse model><multidisciplinary><murine model><newborn child><newborn children><obese mothers><obesity risk><offspring><people who are pregnant><pre-clinical trial><pre-eclamptic><preclinical trial><pregnancy toxemia/hypertension><pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><programs><respiratory><risk for obesity><risk of obesity><sex><systemic inflammation><systemic inflammatory response><therapeutic target><those who are pregnant><women who are pregnant>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Victor Afriyie Ansere

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Exploratory lead · 30/100

Recent

Active award

Career award

$78,734

FY 2026

Project Title

Reversing age-related epigenetic changes and characterizing microglia heterogeneity in obesity and aging

Grant Number:

5K00AG079813-05

Activity Code:

K00

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/1/2022

End Date:

1/31/2028

Project Abstract

Project Summary Neuroinflammation is a hallmark of brain aging that may contribute to declines in function and neurodegenerative diseases. As the resident macrophage of the brain, microglial are crucial to brain maintenance but have been demonstrated to take on pro-inflammatory phenotypes with aging...

Research Terms

<3 year old><3 years of age><Address><Affect><Affinity Chromatography><Age><Aging><Ammon Horn><Animals><Applied Skills><Assay><BODIPY><BS-seq><Bioassay><Bioinformatics><Biological Assay><Biology><Bisulfite-based sequencing><Blood Plasma><Blood Volume><Body Tissues><Brain><Brain Nervous System><Caloric Restriction><Cell Body><Cell Nucleus><Cells><Chemotactic Cytokines><Communication><Cornu Ammonis><DNA><DNA Methylation><DNA Modification><DNA Modification Process><Data><Degenerative Neurologic Disorders><Deoxyribonucleic Acid><Development><Disease><Disorder><Dysfunction><Elements><Encephalon><Enhancers><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Epigenetic age><Fats><Fatty acid glycerol esters><Fluorescence Activated Cell Sorting Fractionation><Fluorescence-Activated Cell Sorting><Fluorescence-Activated Cell Sortings><Foundations><Functional disorder><Future><Gene Expression><Genes><Genomics><Goals><Grant><GrimAge clock><Hannum clock><Heterogeneity><High Fat Diet><Hippocampus><Homologous Chemotactic Cytokines><Hortega cell><Horvath clock><Immune Cell Activation><Impairment><Inflammation><Inflammatory><Intercrines><Intervention><Knowledge><Laboratories><Leanness><Lipids><Macrophage><Maintenance><Manuscripts><Mentors><Messenger RNA><Methylation><Mice><Mice Mammals><Microglia><Modeling><Molecular><Morphology><Murine><Mus><Mφ><Nervous System Degenerative Diseases><Neural Degenerative Diseases><Neural degenerative Disorders><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Non-Polyadenylated RNA><Nuclear><Nucleus><Nutritional><Obese Mice><Obesity><Operative Procedures><Operative Surgical Procedures><Oral><Pathologic><Pattern><Phagocytes><Phagocytic Cell><Phase><PhenoAge clocks><Phenotype><Physiologic><Physiological><Physiopathology><Plasma><Plasma Serum><Population><RNA><RNA Gene Products><RNA Seq><RNA sequencing><RNAseq><Research><Reticuloendothelial System, Serum, Plasma><Ribonucleic Acid><Ribosomes><Role><SIS cytokines><Saline><Saline Solution><Scientist><Site><Sorting><Structure><Surgical><Surgical Interventions><Surgical Procedure><Technical Expertise><Techniques><Technology><Testing><Thinness><Tissues><Training><Translating><Writing><adiposity><affinity purification><age 3><age 3 years><age associated><age associated alterations><age associated changes><age correlated><age correlated alterations><age correlated changes><age dependent><age dependent alterations><age dependent changes><age group><age induced alterations><age induced changes><age linked><age related><age related alterations><age related changes><age reversal><age specific><age specific alterations><age specific changes><aged brain><aged mice><aged mouse><ages><aging associated alterations><aging associated changes><aging brain><aging correlated alterations><aging correlated changes><aging dependent alterations><aging dependent changes><aging induced alterations><aging induced changes><aging induced epigenetic change><aging prevention><aging preventive intervention><aging related alterations><aging related changes><aging reversal><aging specific alterations><aging specific changes><aging-associated epigenetic change><aging-related epigenetic change><alleviate age related><alleviate aging><alterations with age><amebocyte><ameliorating aging><anti aging><anti geronic><anti-aging intervention><antiaging><bisulfite sequencing><bisulfite-seq><calorie restriction><career><cell type><changes with age><chemoattractant cytokine><chemokine><corpulence><counter age related><counter aging><counteract age related><counteract aging><cytokine><decline in function><decline in functional status><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><design><designing><developmental><diet-associated obesity><diet-induced obesity><diet-related obesity><dietary><elderly mice><entire genome><epigenetic age clocks><epigenetic aging><epigenetic clock><epigenetic mechanisms in aging><epigenetic modifications in aging><epigenetic molecular clocks><epigenetic regulation of aging><epigenetically><epigenome><epigenome editing><epigenomic editing><epigenomics><experience><full genome><functional decline><functional status decline><gitter cell><hippocampal><immune activation><improved><innovate><innovation><innovative><insight><interest><interventions targeting aging><lab experience><lab training><laboratory experience><laboratory training><late in life><late life><mRNA><mesoglia><methylation clock><microglial cell><microgliocyte><molecular phenotype><mouse model><murine model><neural inflammation><neurodegenerative illness><neuroinflammation><neuroinflammatory><new approaches><novel approaches><novel strategies><novel strategy><nutritious><ob/ob mouse><old mice><pathophysiology><perivascular glial cell><prevent><prevent age related><prevent aging><preventing><rejuvenating intervention><rejuvenation approach><rejuvenation strategies><rejuvenation therapy><rejuvenation treatment><response><reverse age><reverse aging><reverse aging effects><reversible aging><scRNA sequencing><scRNA-seq><sex><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><skills><social role><suppress aging><surgery><systemic inflammation><systemic inflammatory response><technical skills><therapeutic rejuvenation><three year old><three years of age><transcriptome sequencing><transcriptomic sequencing><transcriptomics><translational study><translatome><uptake><whole genome>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Thomas Cardaci

COLORADO STATE UNIVERSITY, FORT COLLINS, CO

Exploratory lead · 24/100

Active award

Career award

$99,216

FY 2026

Project Title

Intercellular Communication in Cancer Cachexia: Impact of Obesity and Exercise

Grant Number:

4K00CA294251-03

Activity Code:

K00

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2024

End Date:

11/30/2029

Project Abstract

Research: At the time of cancer diagnosis, 40%–60% of patients are overweight or obese. Despite this, there is a lack in understanding how pre-existing obesity influences the development and severity of cancer cachexia— a multifactorial wasting syndrome characterized by the unintentional loss of lea...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Abbey Blake

UNIVERSITY OF CALIFORNIA BERKELEY, BERKELEY, CA

Exploratory lead · 24/100

Training-friendly

$17,283

FY 2026

Project Title

Evaluating the Role of Human Obesity Genes in Specific Neuronal Populations in vivo by CRISPRi

Grant Number:

5F31DK137538-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/1/2024

End Date:

12/31/2025

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT ABSTRACT Obesity leads to an increased risk for type 2 diabetes, heart attack, hypertension, stroke, and many types of cancer—conditions which are among the leading causes of death in the US. Through twin and family studies, obesity has been found to have a 40-70% heritability rate, pointing...

Research Terms

<21+ years old><ACTH-beta-Lipotropin Precursor><Ablation><Adeno-Associated Viruses><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Alleles><Allelomorphs><Alstrom syndrome><Alstrom-Hallgren syndrome><Alström Syndrome><Anatomic Sites><Anatomic structures><Anatomy><Apoplexy><Arcuate Nucleus><Autoregulation><Bardet Biedel syndrome><Bardet-Biedl Syndrome><Body Weight><Brain Vascular Accident><CRISPR><CRISPR interference><CRISPR-dCas9-mediated repression><CRISPR/Cas system><CRISPR/dCas9 interference><CRISPR/dCas9-mediated transcriptional inhibition><CRISPRi><Cancers><Cardiac infarction><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Membrane Extensions><Cell Membrane Projections><Cell Membrane Protrusions><Cell Signaling><Cell Surface Extensions><Cell Surface Projections><Cell Surface Protrusions><Cell model><Cells><Cellular model><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cilia><Clustered Regularly Interspaced Short Palindromic Repeats><Clustered Regularly Interspaced Short Palindromic Repeats interference><Complex><Corticotropin-beta-Lipotropin Precursor><DNA mutation><Data><Defect><Dependoparvovirus><Dependovirus><Development><Down-Regulation><Eating><Endorphin-ACTH Precursor><Epistasis><Epistatic Deviation><Family Study><Food Intake><Gene Alteration><Gene Down-Regulation><Gene Expression><Gene Mutation><Gene Transcription><Genes><Genetic Change><Genetic Diversity><Genetic Epistasis><Genetic Transcription><Genetic Variation><Genetic defect><Genetic mutation><Guide RNA><Heritability><Homeostasis><Human><Hypertension><Hypothalamic structure><Hypothalamus><Infundibular Nucleus><Interaction Deviation><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Laboratories><Leptin><MC4 Receptor><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Mediating><Melanocortin 4 Receptor><Mice><Mice Mammals><Modeling><Modern Man><Morbid Obesity><Murine><Mus><Mutation><Myocardial Infarct><Myocardial Infarction><NIDDM><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Ob Gene Product><Ob Protein><Obese Gene Product><Obese Protein><Obesity><Organelles><Output><Paraventricular Hypothalamic Nucleus><Patients><Persons><Physiologic><Physiological><Physiological Homeostasis><Population><Pro-ACTH-Endorphin><Pro-Opio-Melanocortin><Pro-Opiocortin><Pro-Opiomelanocortin><Proopiocortin><Proopiomelanocortin><Proteins><Public Health><Quality Control><RNA Expression><Receptor, Melanocortin, Type 4><Regulation><Research><Research Proposals><Risk><Role><Severe obesity><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Specificity><Stable Diabetes Mellitus><Stroke><Structure of nucleus infundibularis hypothalami><System><T2 DM><T2D><T2DM><Technology><Testing><Therapeutic><Transcription><Transcription Repression><Twin Studies><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Validation><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><adeno associated virus group><adenylyl cyclase III><adenylyl cyclase type III><adiposity><adult onset diabetes><adulthood><biological signal transduction><brain attack><cancer type><cardiac infarct><cell type><cerebral vascular accident><cerebrovascular accident><ciliopathy><coronary attack><coronary infarct><coronary infarction><corpulence><developmental><epistatic interaction><epistatic relationship><extreme obesity><family focused study><family survey><gRNA><gene defect><gene manipulation><gene repression><gene x gene interaction><genetic epistases><genetic etiology><genetic manipulation><genetic mechanism of disease><genetically manipulate><genetically perturb><genome mutation><heart attack><heart infarct><heart infarction><high blood pressure><human disease><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypothalamic><improved><in vivo><induced Cre><inducible Cre><ketosis resistant diabetes><malignancy><maturity onset diabetes><mutant allele><neoplasm/cancer><neuronal><paraventricular nucleus><repressing CRISPR-dCas9 system><social role><stroked><strokes><tool><type 2 DM><type II DM><type two diabetes><validations>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Catherine Cioffi Cohen

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Exploratory lead · 22/100

Recent

Active award

$248,965

FY 2026

Project Title

Pancreatic fat and volume and childhood metabolic health

Grant Number:

4R00DK136503-03

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2026

End Date:

2/28/2029

Project Abstract

PROJECT SUMMARY/ABSTRACT The rise of type 2 diabetes (T2D) in U.S. youth is an alarming public health issue. Although obesity is a strong risk factor for pediatric T2D, at the same time, only a subset of youth with obesity develops T2D, suggesting disease pathogenesis is driven by factors beyond tot...

Research Terms

<0-11 years old><12-20 years old><Abdomen><Adolescence><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Age><Autoregulation><Award><BMI><BMI percentile><BMI z-score><Birth><Body Composition><Body fat><Body mass index><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Clinical><Cohort Studies><Colorado><Complement><Complement Proteins><Complex><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Dextrose><Diet><Disease><Disease Frequency Surveys><Disorder><Doctor of Philosophy><Dysfunction><Enrollment><Environment><Ethnic Origin><Ethnicity><Fats><Fatty Liver><Fatty acid glycerol esters><Functional disorder><Funding><Generalized Growth><Gestation><Glucose><Goals><Growth><Growth Agents><Growth Factor><Growth Substances><Health><Hepatic><Heterogeneity><Homeostasis><Hour><Human><Humulin R><Image><Individual><Infant><Insulin><Insulin homeostasis><Joints><Ketosis-Resistant Diabetes Mellitus><Knowledge><Life Cycle><Life Cycle Stages><Life course epidemiology><Lifecourse epidemiology><Lipid Trafficking><Liver Steatosis><MR Imaging><MR Tomography><MRI><MRI Scans><MRIs><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Malnutrition><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Mentors><Mentorship><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic dysfunction><Modern Man><Mothers><NIDDM><NMR Imaging><NMR Tomography><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nuclear Magnetic Resonance Imaging><Nutrition><Nutritional><Nutritional Deficiency><OGTT><Obesity><Observational research><Onset of illness><Oral Glucose Tolerance Test><Overnutrition><Pancreas><Pancreatic><Parents><Parturition><Pathogenesis><Pathway interactions><Ph.D.><PhD><Phase><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Play><Population><Pregnancy><Pregnant Women><Preventative strategy><Prevention strategy><Preventive strategy><Prospective Studies><Proteins Growth Factors><Puberty><Public Health><Quetelet index><Regular Insulin><Research><Research Activity><Risk><Risk Factors><Risk Marker><Role><Scanning><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Thesaurismosis><Time><Tissue Growth><Training><Training Activity><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Undernutrition><Variant><Variation><Visceral><Visit><Youth><Youth 10-21><Zeugmatography><abdominal adiposity><abdominal fat><adiposity><adolescence (12-20)><adult onset diabetes><ages><birth cohort study><birth cohort survey><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><cohort research study><cohort survey><complementation><corpulence><cross-sectional research study><demographics><design><designing><dietary deficiency><diets><disease onset><disorder onset><early adolescence><early onset><enroll><expectant mother><expectant women><expecting mother><expecting women><experience><falls><hepatic steatosis><hepatosteatosis><imaging><improved><indexing><individuals who are pregnant><infancy><infantile><insight><insulin balance><insulin control><inter-individual variability><inter-individual variation><investigate observational><juvenile><juvenile human><ketosis resistant diabetes><kids><life course><lipid transport><malnourished><maturity onset diabetes><metabolism disorder><nutrition deficiency><nutrition deficiency disorder><nutritional deficiency disorder><nutritious><obese children><obesity during childhood><obesity in children><observational investigation><offspring><ontogeny><parent><parent grant><pathophysiology><pathway><pediatric><pediatric obesity><people who are pregnant><postnatal><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prevent><preventing><programs><prospective research study><prospective survey><prospective test><risk predictor><risk predictors><sex><skill acquisition><skill development><skills><social role><study observational><survey observational><those who are pregnant><trafficking><training module><trait><trend><type 2 DM><type II DM><type two diabetes><unborn><women who are pregnant><youngster><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ANDREW S GREENBERG

TUFTS UNIVERSITY BOSTON, BOSTON, MA

Exploratory lead · 22/100

Recent

Active award

$232,000

FY 2026

Project Title

Role of adipocyte interferon regulatory factor 8 in adipocyte and systemic metabolism and diet-induced obesity

Grant Number:

1R56DK141683-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/12/2026

End Date:

2/28/2027

Project Abstract

If there is no change, enter No changes to the abstract or NONE. Adipocyte dyfuntion results in reduced BAT thermogenesis, low-grade chronic inflammation, fatty liver, and systemic insulin resistance. Still poorly understood are the mechanisms that trigger diet-induced obesity-associated adipocyte d...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MATTHEW L MACIEJEWSKI

EDITH NOURSE ROGERS MEMORIAL VETERANS HOSPITAL, BEDFORD, MA

Exploratory lead · 22/100

Recent

Active award

$0

FY 2026

Project Title

Comparative Effectiveness and Stakeholder Perspectives with Anti-Obesity Medications

Grant Number:

1I01RD000431-01A2

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

1/1/2026

End Date:

12/31/2029

Project Abstract

Significance to VA Obesity is present among 41% of VA patients and incurs many physical and mental health problems, increases mortality, and accounts for a large share of health care spending. Despite significant VA investment in the MOVE! behavioral intervention program and availability of bariatri...

Research Terms

<21+ years old><Acceleration><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Adverse effects><Anti-Obesity Agents><Anti-Obesity Drugs><Apoplexy><Applications Grants><Asthma><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Benefits and Risks><Blood Pressure><Body Weight Changes><Body Weight decreased><Brain Vascular Accident><Bronchial Asthma><Cancers><Cardiac Diseases><Cardiac Disorders><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Clinical><Clinical Practice Guideline><Complement><Complement Proteins><Conditioning Therapy><Coupled><Data><Decision Making><Degenerative Arthritis><Degenerative polyarthritis><Drug Prescribing><Drug Prescriptions><Effectiveness><Eligibility><Eligibility Determination><Ensure><Ethnic Origin><Ethnicity><Food and Drug Administration><Foundations><Future><General Population><General Public><Goals><Grant Proposals><Guidelines><Health><Health Benefit><Health Care><Health Care Costs><Health Costs><Health Promotion><Heart Diseases><High Prevalence><Hypertension><Intervention><Interview><Investments><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leadership><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Mental Depression><Mental Health><Mental Hygiene><Meta-Analysis><Methodology><Methods><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obstructive Sleep Apnea><Operative Procedures><Operative Surgical Procedures><Osteoarthritis><Osteoarthrosis><Outcome><Participant><Patients><Pattern><Pharmacies><Pharmacy facility><Phase><Policy Maker><Population><Professional Organizations><Protocol Screening><Psychological Health><QOL><Quality of life><Race><Races><Recommendation><Reporting><Research><Research Design><Research Priority><Research Resources><Resources><Risk><Salutogenesis><Sampling><Science><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><Study Type><Surgical><Surgical Interventions><Surgical Procedure><Syndrome, Sleep Apnea, Obstructive><T2 DM><T2D><T2DM><Testing><Time><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><USFDA><United States><United States Food and Drug Administration><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Veterans><Weight><Weight Change><Weight Loss><Weight Reduction><Work><adiposity><adult onset diabetes><adulthood><anti-obesity compounds><anti-obesity medications><anti-obesity therapeutics><arm><bariatric surgery><behavior intervention><behavioral intervention><body weight loss><brain attack><cardiometabolic><cardiometabolism><cerebral vascular accident><cerebrovascular accident><clinical practice and guidelines><clinical significance><clinically significant><co-morbid><co-morbidity><comorbidity><comparative effectiveness><comparative effectiveness study><complementation><corpulence><cost><cost effective><data collected in real world><degenerative joint disease><depression><design><designing><diabetes control><diabetes mellitus control><disease prevention><disorder prevention><evidence base><experience><fatty liver disease><gastric banding><gastric bypass surgery><gastrointestinal><health record><heart disorder><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypertrophic arthritis><implantable gastric stimulation banding><improved><innovate><innovation><innovative><interest><intervention program><ketosis resistant diabetes><malignancy><maturity onset diabetes><medication prescription><men><mortality><neoplasm/cancer><non-diabetic><nondiabetic><obese patients><obesity intervention><obesity management><obesity surgery><obesity therapy><obesity treatment><patients with obesity><pharmacy benefit><physical conditioning><physical health><preference><prescribed medication><professional association><professional membership><professional society><programs><promoting health><racial><racial background><racial origin><real world data><real world evidence><side effect><stakeholder insights><stakeholder perspectives><stomach stapling><stroked><strokes><study design><surgery><translation><treatment planning><type 2 DM><type II DM><type two diabetes><uptake><weight loss surgery><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Varsha Vimalananda

EDITH NOURSE ROGERS MEMORIAL VETERANS HOSPITAL, BEDFORD, MA

Exploratory lead · 22/100

Recent

Active award

$0

FY 2026

Project Title

Comparative Effectiveness and Stakeholder Perspectives with Anti-Obesity Medications

Grant Number:

1I01RD000431-01A2

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

1/1/2026

End Date:

12/31/2029

Project Abstract

Significance to VA Obesity is present among 41% of VA patients and incurs many physical and mental health problems, increases mortality, and accounts for a large share of health care spending. Despite significant VA investment in the MOVE! behavioral intervention program and availability of bariatri...

Research Terms

<21+ years old><Acceleration><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Adverse effects><Anti-Obesity Agents><Anti-Obesity Drugs><Apoplexy><Applications Grants><Asthma><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Benefits and Risks><Blood Pressure><Body Weight Changes><Body Weight decreased><Brain Vascular Accident><Bronchial Asthma><Cancers><Cardiac Diseases><Cardiac Disorders><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Clinical><Clinical Practice Guideline><Complement><Complement Proteins><Conditioning Therapy><Coupled><Data><Decision Making><Degenerative Arthritis><Degenerative polyarthritis><Drug Prescribing><Drug Prescriptions><Effectiveness><Eligibility><Eligibility Determination><Ensure><Ethnic Origin><Ethnicity><Food and Drug Administration><Foundations><Future><General Population><General Public><Goals><Grant Proposals><Guidelines><Health><Health Benefit><Health Care><Health Care Costs><Health Costs><Health Promotion><Heart Diseases><High Prevalence><Hypertension><Intervention><Interview><Investments><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leadership><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Mental Depression><Mental Health><Mental Hygiene><Meta-Analysis><Methodology><Methods><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obstructive Sleep Apnea><Operative Procedures><Operative Surgical Procedures><Osteoarthritis><Osteoarthrosis><Outcome><Participant><Patients><Pattern><Pharmacies><Pharmacy facility><Phase><Policy Maker><Population><Professional Organizations><Protocol Screening><Psychological Health><QOL><Quality of life><Race><Races><Recommendation><Reporting><Research><Research Design><Research Priority><Research Resources><Resources><Risk><Salutogenesis><Sampling><Science><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><Study Type><Surgical><Surgical Interventions><Surgical Procedure><Syndrome, Sleep Apnea, Obstructive><T2 DM><T2D><T2DM><Testing><Time><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><USFDA><United States><United States Food and Drug Administration><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Veterans><Weight><Weight Change><Weight Loss><Weight Reduction><Work><adiposity><adult onset diabetes><adulthood><anti-obesity compounds><anti-obesity medications><anti-obesity therapeutics><arm><bariatric surgery><behavior intervention><behavioral intervention><body weight loss><brain attack><cardiometabolic><cardiometabolism><cerebral vascular accident><cerebrovascular accident><clinical practice and guidelines><clinical significance><clinically significant><co-morbid><co-morbidity><comorbidity><comparative effectiveness><comparative effectiveness study><complementation><corpulence><cost><cost effective><data collected in real world><degenerative joint disease><depression><design><designing><diabetes control><diabetes mellitus control><disease prevention><disorder prevention><evidence base><experience><fatty liver disease><gastric banding><gastric bypass surgery><gastrointestinal><health record><heart disorder><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypertrophic arthritis><implantable gastric stimulation banding><improved><innovate><innovation><innovative><interest><intervention program><ketosis resistant diabetes><malignancy><maturity onset diabetes><medication prescription><men><mortality><neoplasm/cancer><non-diabetic><nondiabetic><obese patients><obesity intervention><obesity management><obesity surgery><obesity therapy><obesity treatment><patients with obesity><pharmacy benefit><physical conditioning><physical health><preference><prescribed medication><professional association><professional membership><professional society><programs><promoting health><racial><racial background><racial origin><real world data><real world evidence><side effect><stakeholder insights><stakeholder perspectives><stomach stapling><stroked><strokes><study design><surgery><translation><treatment planning><type 2 DM><type II DM><type two diabetes><uptake><weight loss surgery><weights><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MATTHEW Anthony SCHIEFER

VETERANS HEALTH ADMINISTRATION, GAINESVILLE, FL

Exploratory lead · 22/100

Recent

Active award

$0

FY 2026

Project Title

Developing a novel stimulus paradigm and interface of vagal nerve stimulation (VNS) to treat obesity

Grant Number:

5I01RX003967-05

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

4/1/2022

End Date:

3/31/2027

Project Abstract

Rationale: By 2018, 31 states had an obesity rate ≥30% and none <20%. Costs due to obesity are estimated at $190B/yr. 72% of Veterans are overweight (45%) or obese (27%), of which 66% have hypertension and 31% have diabetes. Researchers use vagal nerve stimulation (VNS) to treat a number of conditio...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Julie Rekant

BALTIMORE VA MEDICAL CENTER, BALTIMORE, MD

Exploratory lead · 22/100

Recent

Active award

$0

FY 2026

Project Title

Health promotion with targeted exercise intervention for decreasing fall risk and inactivity in aging Veterans with obesity and signs of sarcopenia

Grant Number:

1IK2RD000462-01A1

Activity Code:

IK2

Mechanism:

Other

Agency:

VA

Start Date:

4/1/2026

End Date:

3/31/2031

Project Abstract

Significance to VA: Older Veterans with obesity and sarcopenia (1.2 million Veterans) are three times more likely to fall and six times more likely to become frail than older Veterans without these conditions. Current guidelines recommend weight loss for all Veterans with obesity. However, declines ...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Acceleration><Accelerometer><Accountability><Address><Admission><Admission activity><Adult><Adult Human><Advisory Committees><Affect><Age><Aged 65 and Over><Aging><American><Area><Award><BMI><BMI percentile><BMI z-score><Behavior><Biomechanics><Body Weight decreased><Body mass index><Bone Density><Bone Mineral Density><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Caloric Restriction><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Clinical><Clinical Practice Guideline><Clinical Trials><Communities><Community Participation><Computed Tomography><Conduct Clinical Trials><Development><Education><Educational aspects><Elderly><Engineering><Equilibrium><Exercise><Expert Opinion><Fall prevention><Fats><Fatty acid glycerol esters><Female><Foundations><Fracture><Gait><Gait speed><Goals><Grip strength><Guidelines><Hand Strength><Health><Health Promotion><Health Promotion and Education><Health Promotion and Instruction><Health Promotion and Training><Image><Infiltration><Intervention><K-Awards><K-Series Research Career Programs><Knowledge><Link><Loneliness><Long-Term Care><Lower Extremity><Lower Limb><Measures><Medical><Membrum inferius><Mentors><Methodology><Morbidity><Morphology><Movement><Muscle><Muscle Tissue><Muscle function><Obesity><Pain><Painful><Patient Self-Report><Pattern><Performance><Physical Function><Physical activity><Physiologic><Physiological><Physiological Adaptation><Play><Position><Positioning Attribute><Preventative intervention><Quetelet index><Randomized><Recommendation><Reporting><Research><Research Activity><Research Career Program><Risk><Role><Running><Salutogenesis><Self-Report><Site><Step Tests><Task Forces><Testing><Time><Tomodensitometry><Training><Translations><Veterans><Veterans Health Administration><Veterans Health Affairs><Walking><Weight Loss><Weight Reduction><Weight maintenance regimen><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><above age 65><accelerometry><actigraph><actigraphy><activity monitor><activity tracker><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><advanced age><advisory team><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age associated muscle atrophy><age of 65 years onward><age-associated decline in muscle><age-associated muscle decline><age-associated muscle deterioration><age-associated muscle loss><age-associated muscle wasting><age-related decline in muscle><age-related muscle decline><age-related muscle deterioration><age-related muscle loss><age-related muscle wasting><aged 65 and greater><aged 65+><aged ≥65><ages><attenuation><balance><balance function><behavior change><biomechanical><body movement><body sensor><body weight loss><body worn sensor><bone fracture><calorie restriction><career><catscan><clinical practice and guidelines><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><corpulence><cost><death risk><decline in function><decline in functional status><decrease disability><decrease in disability><design><designing><developmental><disability><disability reduction><effective intervention><efficacious intervention><empowerment><exercise intervention><experience><extended care><fall risk><falls><fitbit><fracture risk><functional decline><functional disability><functional status decline><gait symmetry><geriatric><human old age (65+)><imaging><improved><improved mobility><innovate><innovation><innovative><intervention for prevention><lessen disability><lonely><male><minimize disability><mitigate disability><mobility enhancement><mobility improvement><mortality><mortality risk><multi-modality><multimodality><muscle bulk><muscle form><muscle mass><muscle physiology><muscle strength><muscular><new approaches><non-contrast CT><noncontrast CT><noncontrast computed tomography><novel approaches><novel strategies><novel strategy><optimized mobility><over 65 years><peer><physical activity intervention><physical therapist><physiotherapist><preservation><preventing falls><prevention intervention><preventional intervention strategy><preventive intervention><primary outcome><programs><promoting health><randomisation><randomization><randomly assigned><reduction in disability><research study><response><sarcopenia><sarcopenic><sarcopenic obesity><senior citizen><skills><slow disability><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><translation><virtual group><wearable biosensor><wearable sensor><wearable sensor technology><weight control><weight management><wt-loss><≥65 years><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

TERRY L. SHEPPARD

KEYSTONE SYMPOSIA, SILVERTHORNE, CO

Exploratory lead · 16/100

Active award

$18,100

FY 2026

Project Title

Cardiometabolism in Health and Disease

Grant Number:

1R13HL184864-01

Activity Code:

R13

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/21/2026

End Date:

12/31/2026

Project Abstract

Abstract Support is requested for a Keystone Symposia conference entitled “Cardiometabolism in Health and Disease,” organized by Drs. Daniel P. Kelly, Rong Tian and William C. Sessa, with scientific programming input from Keystone Symposia. The meeting will take place January 26–29, 2026 at the Keys...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Niketa A. Patel

JAMES A. HALEY VA MEDICAL CENTER, TAMPA, FL

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Adipose stem cells' niche in obesity

Grant Number:

5I01BX003836-09

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

4/1/2017

End Date:

12/31/2028

Project Abstract

Obesity continues to escalate as a significant public health problem and as the leading preventable cause of death. Stark data from COVID19 pandemic shows obesity is an independent risk factor of severity with 33% mortality rate. Obesity per se is not fatal but is the major health risk factor promot...

Research Terms

<21+ years old><Adipocytes><Adipose Cell><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Afghanistan><Autoregulation><BMI><BMI percentile><BMI z-score><Biochemical><Biology><Blood Vessels><Body mass index><COVID crisis><COVID epidemic><COVID pandemic><COVID-19><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><CV-19><Cancers><Cardiovascular Diseases><Caring><Cause of Death><Cell Body><Cells><Chronic><Chronic Disease><Chronic Illness><Clinical><Core Facility><Coronavirus Infectious Disease 2019><Data><Death Rate><Department of Defense><Development><Diabetes Mellitus><Differentiation in cell culture><Disease><Disorder><Endocrine><Evaluation><Fat Cells><Fat progenitor cell><Fat stem cell><Fatality rate><Fatty Tissue><Functional RNA><Genes><Genetic><Genomic medicine><Glucocorticoid Receptor><Goals><Guidelines><Gulf War><Health><Health Care Costs><Health Costs><Health Expenditures><Homeostasis><Human><Humulin R><Hyperplasia><Hyperplastic><Hypertrophy><In Vitro><In vitro cell differentiation><Inflammation><Inflammatory><Insulin><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin Resistance><Insulin-Dependent Tyrosine Protein Kinase><Intermediary Metabolism><Investigators><Iraq><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Lipocytes><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Mediating><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Pathway><Metabolic Processes><Metabolic dysfunction><Metabolic stress><Metabolic syndrome><Metabolism><Mice><Mice Mammals><Modern Man><Molecular><Morbid Obesity><Murine><Mus><NCHS><NIDDM><National Center for Health Statistics><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Polyadenylated RNA><Non-sense Mediated Decay><Noncoding RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonsense-Mediated Decay><Nontranslated RNA><Novolin R><Obese Mice><Obesity><Operation Desert Shield><Operation Desert Storm><Overweight><Pathology><Pathway interactions><Pattern><Physiologic><Physiological><Physiological Homeostasis><Plasmids><Population><Public Health><Quetelet index><RNA><RNA Gene Products><Receptor Protein><Regular Insulin><Regulator Genes><Reporting><Research><Research Personnel><Researchers><Ribonucleic Acid><Risk Factors><Role><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severe obesity><Severities><Short interfering RNA><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Thesaurismosis><Thinness><Tissue Differentiation><Transcriptional Regulatory Elements><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States Department of Veterans Affairs><United States National Center for Health Statistics><United States Veterans Administration><Untranslated RNA><Veterans><Veterans Administration><Veterans Affairs><Woman><Work><adipocyte progenitors><adipocyte stem cell><adipocyte-derived stem cell><adipogenesis><adipose><adipose derived stem cell><adipose progenitor><adipose stem cell><adipose tissue derived stem cell><adipose tissue stem cells><adiposity><adult onset diabetes><adulthood><beneficiary><cardiovascular disorder><chronic disorder><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><coronavirus infectious disease-19><corpulence><developmental><diabetes><diet-associated obesity><diet-induced obesity><diet-related obesity><differentiation in culture><differentiation in vitro><experience><experiment><experimental research><experimental study><experiments><extreme obesity><fat derived stem cell><frontier><gas 5 RNA><gas5 RNA><genetic make-up><genetic makeup><genetic trans acting element><genome medicine><growth arrest gas-5 gene product><growth arrest specific transcript 5><health care expenditure><in vitro cellular differentiation><in vivo><individual patient><insulin resistant><insulin signaling><insulin tolerance><interdisciplinary approach><ketosis resistant diabetes><lipid biosynthesis><lipogenesis><malignancy><maturity onset diabetes><medical expenditure><metabolism disorder><military veteran><mortality><mortality rate><mouse model><multidisciplinary approach><murine model><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><noncoding><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><ob/ob mouse><obese individuals><obese patients><obese people><obese person><obese population><obese subjects><obesity intervention><obesity therapy><obesity treatment><overexpress><overexpression><pathway><patients with obesity><pre-clinical><preclinical><prevent><preventing><progenitor cell differentiation><progenitor cell markers><progenitor cell niche><progenitor differentiation><progenitor markers><progenitor niche><progenitor stem cell markers><receptor><regulatory gene><screening><screenings><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><siRNA><social role><statistics><stem and progenitor cell niche><stem and progenitor differentiation><stem cell biomarkers><stem cell differentiation><stem cell markers><stem cell niche><tool><trans acting element><transcriptomics><type 2 DM><type II DM><type two diabetes><vascular><veteran population><white adipose tissue><yellow adipose tissue>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KAMAL RAHMOUNI

IOWA CITY VA MEDICAL CENTER, IOWA CITY, IA

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Neuronal Mechanisms of Obesity-Induced Hypertension

Grant Number:

5I01BX004249-08

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

1/1/2019

End Date:

12/31/2026

Project Abstract

The high prevalence of obesity among the veterans is a major challenge for the VA healthcare system. This is because obesity is associated with increased sympathetic nerve traffic leading to hypertension, a major risk factor for end-organ damage, stroke, myocardial infarction and congestive heart fa...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Carlos Bernal-Mizrachi

ST. LOUIS VA MEDICAL CENTER, St. Louis, MO

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Vitamin D and Development Origins of Obesity and Insulin Resistance

Grant Number:

5I01BX003648-08

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

7/1/2018

End Date:

1/31/2027

Project Abstract

early 80% of the Veterans are either overweight or obese, increasing their risk of hypertension, diabetes, and cardiovascular disease. Accumulation of excess adiposity in this population begins at an early age, as nearly 20% of young active-duty veterans are obese, suggesting that this metabolic der...

Research Terms

<0-11 years old><10 year old><10 years of age><1st trimester><4 year old><4 years of age><Address><Adipocytes><Adipose Cell><Adipose tissue><Age><Area><Armed Forces Personnel><Avitaminosis><Award><BMI><BMI percentile><BMI z-score><Birth><Blood Precursor Cell><Blood Sample><Blood Serum><Blood monocyte><Blood specimen><Body Tissues><Body mass index><Bone Marrow><Bone Marrow Reticuloendothelial System><Breast Feeding><Cardiovascular Diseases><Caring><Cell Body><Cells><Child><Child Youth><Children (0-21)><Cord Blood><Development><Diabetes Mellitus><Differentiation in cell culture><Early Placental Phase><Early treatment><Eating><Eligibility><Eligibility Determination><Embryo><Embryonic><Embryonic Induction><Energy Expenditure><Energy Metabolism><Environmental Factor><Environmental Risk Factor><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Expenditure><Family><Family member><Fat Cells><Fats><Fatty Tissue><Fatty acid glycerol esters><Fibroblasts><First Pregnancy Trimester><First Trimester><Food Intake><Future><General Population><General Public><Generalized Growth><Genetic><Gestation><Growth><Health><Health Care Providers><Health Personnel><Health system><Hematopoietic Progenitor Cells><Hematopoietic stem cells><Human><Hyperglyceridemia><Hypertension><Hypertriglyceridemia><Immune><Immunes><Immunomodulation><In vitro cell differentiation><Incidence><Infant><Infiltration><Insulin Resistance><Life><Lipocytes><Macrophage><Marrow monocyte><Mature Lipocyte><Mature fat cell><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Methylation><Mice><Mice Mammals><Military><Military Personnel><Modern Man><Mothers><Multivitamin><Murine><Mus><Myeloid Cells><Mφ><Obesity><Overweight><Parturition><Pathway interactions><Pattern><Phenotype><Placebos><Population><Predisposition><Pregnancy><Pregnant Women><Prevalence><Process><Proliferating><Protocol Screening><Quetelet index><Raised TG><Raised triglycerides><Randomized, Controlled Trials><Risk><Role><Serum><Sham Treatment><Stimulus><Sun Exposure><Supplementation><Supplementation with vitamin D><Susceptibility><System><Testing><Thesaurismosis><Tissue Differentiation><Tissue Expansion><Tissue Growth><Tissues><Transfection><Transplantation><Umbilical Cord Blood><Upregulation><VIT D><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Veterans><Vitamin D><Vitamin D Deficiency><Vitamin D supplementation><Vitamin Deficiency><Vitamin Deficiency Disorder><Weight><Weight Gain><Weight Increase><Woman><active duty><active service><adipocyte development><adipocyte differentiation><adipose><adiposity><adult youth><age 10><age 10 years><age 4><age 4 years><ages><antenatal><antepartum><blood cell progenitor><blood progenitor><blood stem cell><blood-forming stem cell><body weight gain><body weight increase><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><childbearing age><cohort><corpulence><developmental><diabetes><differentiation in culture><differentiation in vitro><disease risk><disorder risk><early in pregnancy><early pregnancies><early pregnancy><early screening><early stage of pregnancy><early therapy><elevated tg><elevated triglyceride><environmental risk><epigenetically><expectant mother><expectant women><expecting mother><expecting women><fertile age><fetal><fetal cord blood><four year old><four years of age><health care personnel><health care worker><health provider><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic progenitor><hemopoietic stem cell><high blood pressure><high triglycerides><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypovitaminosis><immune modulation><immune regulation><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><improved><in utero><in vitro cellular differentiation><increased triglycerides><individuals who are pregnant><insulin resistant><insulin tolerance><kids><later in life><later life><maternal adiposity><maternal obesity><medical care providers><medical personnel><metabolism disorder><military population><military service><monocyte><obese individuals><obese people><obese person><obese population><obese subjects><obesity development><obesity prevention><obesity risk><offspring><offspring obesity><ontogeny><pathway><people who are pregnant><postnatal><pregnant><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prevent><prevent obesity><preventing><programs><randomized control trial><recruit><reproductive age><reproductive years><risk for obesity><risk of obesity><screening><screenings><sham therapy><social role><solar exposure><specific biomarkers><sun light exposure><sunlight exposure><systemic inflammation><systemic inflammatory response><ten year old><ten years of age><those who are pregnant><transplant><treatment provider><unborn><vitamin D supplement><weights><white adipose tissue><women who are pregnant><wt gain><yellow adipose tissue><young adult><young adult age><young adulthood><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

James Ernest Blevins

VA PUGET SOUND HEALTHCARE SYSTEM, SEATTLE, WA

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Oxytocin Signaling in the Control of Cardiometabolic Function in Diet-Induced Obesity

Grant Number:

5I01BX004102-09

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

1/1/2018

End Date:

12/31/2026

Project Abstract

We and others have shown that the nonapeptide, oxytocin (OT), circumvents leptin resistance to elicit body weight loss in obese rodents, nonhuman primates and humans, by reducing food intake while increasing energy expenditure (EE). The identification of recruitable brown adipose tissue (BAT) in hum...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SHALAMAR D SIBLEY

MINNEAPOLIS VA MEDICAL CENTER, MINNEAPOLIS, MN

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Transcranial Direct Current Stimulation (tDCS) with Cognitive Training to Reduce Impulsivity and Weight in Veterans with Obesity: A Clinical Trial

Grant Number:

5I01CX002121-04

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

4/1/2022

End Date:

12/31/2026

Project Abstract

Impulsivity has been implicated in refractory obesity in bariatric and non-bariatric subjects (Sutin 2011, Filbey 2017, Gunstad 2017, Galioto 2016, Benard 2017). A healthy prefrontal cortex (PFC) may mitigate excess impulsivity effects on appetite regulation by providing critical executive function ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Long-Sheng Song

IOWA CITY VA MEDICAL CENTER, IOWA CITY, IA

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

Junctophilin- 2 in brown Adipocyte Metabolic Regulation and Obesity

Grant Number:

5I01BX006139-02

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

10/1/2024

End Date:

9/30/2028

Project Abstract

Obesity, a state of imbalance between caloric intake and energy expenditure, is a major global problem that increases the risk of developing a wide range of diseases including insulin resistance, type 2 diabetes, cardiovascular disease and COVID-19 among others. Brown adipocytes in brown adipose tis...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David T Ewart

MINNEAPOLIS VA MEDICAL CENTER, MINNEAPOLIS, MN

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

Acoustic and Clinical Outcomes of Next-Generation Pharmacological Weight Loss Therapies on Obesity-Related Osteoarthritis of the Knee

Grant Number:

1IK2RX004802-01A2

Activity Code:

IK2

Mechanism:

Other

Agency:

VA

Start Date:

1/1/2026

End Date:

12/31/2030

Project Abstract

This is an application for a Career Development Award (CDA-2) to Dr. David Ewart, MD, a staff rheumatologist at the Minneapolis VA Medical Center and Assistant Professor at the University of Minnesota. Dr. Ewart’s research area of interest is in osteoarthritis of the knee. His current VA-funded proj...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mohamad Mokadem

IOWA CITY VA MEDICAL CENTER, IOWA CITY, IA

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

Interaction between adipose tissue and central clock via the splanchnic nerve pathway for regulation of energy balance

Grant Number:

5I01BX004774-06

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

1/1/2020

End Date:

9/30/2028

Project Abstract

Obesity is a growing problem in the US, with veterans being at a higher risk of developing it along with diabetes and other obesity-related conditions. Bariatric surgery is one of the most common and effective invasive therapy offered to patients with severe obesity. Time-restricted feeding (TRF) be...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Principal Investigator Finder

Search Principal Investigators

Search Results

Opportunity Digest

David Alan Kass

Project Title

Project Abstract

Research Terms

Michael W Schwartz

Project Title

Project Abstract

Research Terms

JOSHUA P THALER

Project Title

Project Abstract

Research Terms

Jeanie Beatrice Tryggestad

Project Title

Project Abstract

Research Terms

MICHAEL D. JENSEN

Project Title

Project Abstract

Research Terms

ASHLESHA DATAR

Project Title

Project Abstract

Research Terms

Jonathan E Posner

Project Title

Project Abstract

Research Terms

YUN WANG

Project Title

Project Abstract

Research Terms

CHARLES R FLYNN

Project Title

Project Abstract

Research Terms

Sinju Sundaresan

Project Title

Project Abstract

Research Terms

Amy Christine Arnold

Project Title

Project Abstract

Research Terms

Alfredo Gamboa

Project Title

Project Abstract

Research Terms

DAVID A FIELDS

Project Title

Project Abstract

Research Terms

Elvira Marie Isganaitis

Project Title

Project Abstract

Research Terms

Michael C. Rudolph

Project Title

Project Abstract

Research Terms

Caitlin Grace Howe

Project Title

Project Abstract

Research Terms

LINDA Anne BARBOUR

Project Title

Project Abstract

Research Terms

Teri L Hernandez

Project Title

Project Abstract

Research Terms

Stacey Lynn Simon

Project Title

Project Abstract

Research Terms