Clay F. Semenkovich

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

High-opportunity lead · 88/100

Likely hiring

Large award

Very recent

Active award

$1,773,893

FY 2026

Project Title

Diabetes Research Center

Grant Number:

5P30DK020579-49

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/1/1996

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY: Center Overview The Washington University (WashU) School of Medicine (WUSM) Diabetes Research Center (DRC) has a goal of decreasing human suffering by pursuing the scientific theme of interdisciplinary cooperation across the translational research spectrum to develop new therapies ...

Research Terms

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Steven Emanuel Kahn

UNIVERSITY OF WASHINGTON, SEATTLE, WA

High-opportunity lead · 88/100

Likely hiring

Large award

Very recent

Active award

$1,421,361

FY 2026

Project Title

Diabetes Research Center

Grant Number:

5P30DK017047-50

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/1/1996

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The Diabetes Research Center at the University of Washington is part of the national program supported by NIDDK and acts as the focal point and umbrella for diabetes research in the Greater Seattle area. Its mission is to enhance research, education and training in diabetes, obesity, and related dis...

Research Terms

<Adult-Onset Diabetes Mellitus><Area><Basic Research><Basic Science><Bioinformatics><Bioinformatics core><Bioinformatics research core><Bioinformatics resource core><Biomedical Research><Body Weight><Brittle Diabetes Mellitus><Business-Friendly Atmosphere><CRISPR><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas system><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cas nuclease technology><Causality><Cell Body><Cell Culture Techniques><Cells><Clinical Research><Clinical Study><Clinical Trials><Clustered Regularly Interspaced Short Palindromic Repeats><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Collaborations><Communities><Complications of Diabetes Mellitus><Confocal Microscopy><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Direct Costs><Discipline><Disease><Disorder><Dysfunction><Education><Education and Training><Educational aspects><Educational workshop><Ensure><Environment><Etiology><Faculty><Fellowship><Financial Support><Fostering><Functional disorder><Funding><Generations><Goals><Grant><Histopathology><IDDM><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Institution><Insulin-Dependent Diabetes Mellitus><Investigation><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Maturity-Onset Diabetes Mellitus><Metabolic><Mice><Mice Mammals><Mission><Modernization><Murine><Mus><NIDDK><NIDDM><NIH><Names><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Outcome><Pathogenesis><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Peer Review><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D. student><PhD student><PhD. student><Phenotype><Physiopathology><Postdoc><Postdoctoral Fellow><Prevention><Proteomics><Regulation><Research><Research Associate><Research Methodology><Research Methods><Research Personnel><Research Resources><Research Support><Researchers><Resources><Salaries><Scientist><Services><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Sudden-Onset Diabetes Mellitus><Sum><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Training><Training and Education><Transgenic Animals><Transgenic Mice><Translating><Translational Research><Translational Science><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Underrepresented Ethnic Minority><Underrepresented Minority><United States National Institutes of Health><Universities><Viral Vector><Wages><Washington><Work><Workshop><adiposity><adult onset diabetes><base><bases><business-friendly environment><causation><cell culture><cell cultures><cell imaging><cellular imaging><clinical care><clinical investigation><collaborative atmosphere><collaborative environment><conference><convention><corpulence><developmental><diabetes><disease causation><disease prevention><disorder prevention><diversity, equity, and inclusiveness><doctoral student><epidemiology research study><epidemiology study><epidemiology survey><equity, diversity, and inclusion><financial aid><financial assistance><glucose metabolism><graduate student><improved><in vivo><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lectures><maturity onset diabetes><molecular imaging><molecule imaging><name><named><naming><pathophysiology><patient oriented outcomes><peer-group atmosphere><peer-group environment><post-doc><post-doctoral><post-doctoral trainee><prevent><preventing><programs><research and methods><research associates><response><summit><symposia><symposium><tool><translation research><translational investigation><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><under-representation of minorities><under-represented minority><underrepresentation of minorities><vector>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

GRAEME I BELL

UNIVERSITY OF CHICAGO, CHICAGO, IL

High-opportunity lead · 88/100

Likely hiring

Large award

Very recent

Active award

$1,367,386

FY 2026

Project Title

Diabetes Research and Training Center

Grant Number:

5P30DK020595-49

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/1/1996

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY – CENTER OVERVIEW The Chicago Diabetes Research and Training Center (DRTC) is a Chicago area Diabetes Research Center that is centered at the University of Chicago with the participation of investigators from the Northwestern University, the University of Illinois at Chicago, the Ill...

Research Terms

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Raghavendra G Mirmira

UNIVERSITY OF CHICAGO, CHICAGO, IL

High-opportunity lead · 88/100

Likely hiring

Large award

Very recent

Active award

$1,367,386

FY 2026

Project Title

Diabetes Research and Training Center

Grant Number:

5P30DK020595-49

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/1/1996

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY – CENTER OVERVIEW The Chicago Diabetes Research and Training Center (DRTC) is a Chicago area Diabetes Research Center that is centered at the University of Chicago with the participation of investigators from the Northwestern University, the University of Illinois at Chicago, the Ill...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kevan C Herold

YALE UNIVERSITY, NEW HAVEN, CT

High-opportunity lead · 88/100

Likely hiring

Large award

Very recent

Active award

$1,112,136

FY 2026

Project Title

Yale Diabetes Research Center

Grant Number:

5P30DK045735-34

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

1/1/1997

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

OVERALL Modified Project Summary/Abstract of the Administrative Core The Yale Diabetes Research Center (Yale DRC) was established in 1993 with the goal of promoting research in diabetes and related metabolic disorders at Yale. The Yale DRC brings together a multidisciplinary group of 97 members and ...

Research Terms

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GERALD I SHULMAN

YALE UNIVERSITY, NEW HAVEN, CT

High-opportunity lead · 88/100

Likely hiring

Large award

Very recent

Active award

$1,112,136

FY 2026

Project Title

Yale Diabetes Research Center

Grant Number:

5P30DK045735-34

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

1/1/1997

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

OVERALL Modified Project Summary/Abstract of the Administrative Core The Yale Diabetes Research Center (Yale DRC) was established in 1993 with the goal of promoting research in diabetes and related metabolic disorders at Yale. The Yale DRC brings together a multidisciplinary group of 97 members and ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sangeeta Dhawan

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

High-opportunity lead · 82/100

Likely hiring

Above-average budget

Very recent

Active award

$757,946

FY 2026

Project Title

Defining heterogeneity of stress-induced beta cell senescence programs in type 1 diabetes

Grant Number:

1U01DK143458-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2026

End Date:

3/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Type 1 diabetes (T1D) results from insulin insufficiency owing to near complete destruction of insulin- producing pancreatic β-cells by an autoimmune process. Over the last decade, the active participation of pancreatic β-cells in their own autoimmune destruction and the im...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Feyza Engin

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

High-opportunity lead · 82/100

Likely hiring

Above-average budget

Very recent

Active award

$757,946

FY 2026

Project Title

Defining heterogeneity of stress-induced beta cell senescence programs in type 1 diabetes

Grant Number:

1U01DK143458-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2026

End Date:

3/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Type 1 diabetes (T1D) results from insulin insufficiency owing to near complete destruction of insulin- producing pancreatic β-cells by an autoimmune process. Over the last decade, the active participation of pancreatic β-cells in their own autoimmune destruction and the im...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Matthew Wortham

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

High-opportunity lead · 82/100

Likely hiring

Above-average budget

Very recent

Active award

$757,946

FY 2026

Project Title

Defining heterogeneity of stress-induced beta cell senescence programs in type 1 diabetes

Grant Number:

1U01DK143458-01

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2026

End Date:

3/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Type 1 diabetes (T1D) results from insulin insufficiency owing to near complete destruction of insulin- producing pancreatic β-cells by an autoimmune process. Over the last decade, the active participation of pancreatic β-cells in their own autoimmune destruction and the im...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Robert Babak Faryabi

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$4,999,267

FY 2026

Project Title

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D)

Grant Number:

5U01DK123594-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2019

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D) Abstract Building on our existing infrastructure and scientific collaborations, and the expertise gained during the first four years of the HPAP effort for Type 2 Diabetes, we have assembled five cores with expertise ranging from pancrea...

Research Terms

<Adult-Onset Diabetes Mellitus><Age><Antidiabetic Hormone><Assay><B9 endocrine pancreas><BMI><BMI percentile><BMI z-score><Bioassay><Bioenergetics><Biological Assay><Biology><Blood><Blood Reticuloendothelial System><Body Tissues><Body mass index><Brittle Diabetes Mellitus><Calcium><Categories><Causality><Cell Body><Cell surface><Cells><Classification><Clinical Data><Collaborations><Communities><Cyclic GMP><Cyclic Somatostatin><Cytometry><DNA><DNA Sequence><Data><Data Analyses><Data Analysis><Data Bases><Data Discovery><Data Set><Databases><Deoxyribonucleic Acid><Detection><Diabetes Mellitus><Diagnosis><Disease><Disorder><Dysfunction><Endocrine Pancreas><Epidemic><Ethnic Origin><Ethnicity><Etiology><Evaluation><Exhibits><FAIR data><FAIR guiding principles><FAIR principles><Feedback><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Fixation><Functional disorder><Future><Gene Expression><Genes><Genetic><Genomic DNA><Genomics><Glucagon><Glukagon><Growth Hormone Inhibiting Factors><Growth Hormone-Inhibiting Hormone><Guanosine Cyclic Monophosphate><HG-Factor><Heterogeneity><Histologic><Histologically><Human><Humulin R><Hyperglycemic-Glycogenolytic Factor><IDDM><Image><Impairment><Individual><Infrastructure><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Investigators><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Leadership><MODY><Maturity-Onset Diabetes Mellitus><Measurement><Medical History><Medical Records><Metabolic><Metadata><Methodology><Modality><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Natural History><Neighborhoods><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Organ Donor><Organ Procurements><Oxygen Consumption><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Pathologic><Pathology><Personal Medical History><Personal Medical History Epidemiology><Phenotype><Physiologic><Physiological><Physiopathology><Population><Preparation><Process><Proteins><Publications><Quetelet index><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Research><Research Personnel><Research Resources><Researchers><Resolution><Resources><SRIH><SRIH-14><Scientific Publication><Single-Nucleus Sequencing><Slow-Onset Diabetes Mellitus><Somatostatin><Somatostatin-14><Somatotropin Release Inhibiting Factors><Somatotropin Release-Inhibiting Hormone><Sorting><Stable Diabetes Mellitus><Staining method><Stains><Sudden-Onset Diabetes Mellitus><Systematics><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><Visualization><adult onset diabetes><ages><attenuated insulin secretion><biobank><biorepository><blunted insulin secretion><cGMP><causation><clinical diagnosis><clinical phenotype><data access><data base><data deposition><data ecosystem><data harmonization><data integration><data interpretation><data portal><data resource><data sharing><data sharing ecosystem><data sharing portal><data submission><deceased donor><deceased organ donors><decreased insulin release><decreased insulin secretion><defective insulin secretion><demographics><diabetes><diminished insulin release><diminished insulin secretion><disease causation><disease heterogeneity><epigenomics><experience><gDNA><growth hormone release inhibiting factor><harmonized data><high dimensional data><human tissue><imaging><impaired insulin release><impaired insulin secretion><improved><inadequate insulin release><inadequate insulin secretion><indexing><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lowered insulin secretion><maturity onset diabetes><maturity onset diabetes in youth><maturity onset diabetes of the young><member><meta data><methylome><molecular phenotype><molecular profile><molecular signature><morphometry><multidimensional data><multidimensional datasets><multiomics><multiple omics><panomics><pathophysiology><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><posthumous donors><posthumous organ donor><preparations><programs><reduced insulin release><resolutions><response><response to therapy><response to treatment><sNuc-Seq><sample fixation><scATAC sequencing><scATAC-seq><single cell ATAC-seq><single cell ATAC-sequencing><single cell Assay for Transposase Accessible Chromatin sequencing><single cell sequencing assay for transposase accessible chromatin><single nucleus RNA-sequencing><single nucleus seq><single-cell Assay for Transposase-Accessible Chromatin with sequencing><single-cell assay for transposase-accessible chromatin using sequencing><single-cell assay for transposase-accessible chromatin-seq><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><suppressed insulin release><suppressed insulin secretion><therapeutic response><therapy response><tissue archive><transcriptome sequencing><transcriptomic sequencing><treatment response><treatment responsiveness><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><web site><website><whole slide imaging>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KLAUS H KAESTNER

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$4,999,267

FY 2026

Project Title

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D)

Grant Number:

5U01DK123594-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2019

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D) Abstract Building on our existing infrastructure and scientific collaborations, and the expertise gained during the first four years of the HPAP effort for Type 2 Diabetes, we have assembled five cores with expertise ranging from pancrea...

Research Terms

<Adult-Onset Diabetes Mellitus><Age><Antidiabetic Hormone><Assay><B9 endocrine pancreas><BMI><BMI percentile><BMI z-score><Bioassay><Bioenergetics><Biological Assay><Biology><Blood><Blood Reticuloendothelial System><Body Tissues><Body mass index><Brittle Diabetes Mellitus><Calcium><Categories><Causality><Cell Body><Cell surface><Cells><Classification><Clinical Data><Collaborations><Communities><Cyclic GMP><Cyclic Somatostatin><Cytometry><DNA><DNA Sequence><Data><Data Analyses><Data Analysis><Data Bases><Data Discovery><Data Set><Databases><Deoxyribonucleic Acid><Detection><Diabetes Mellitus><Diagnosis><Disease><Disorder><Dysfunction><Endocrine Pancreas><Epidemic><Ethnic Origin><Ethnicity><Etiology><Evaluation><Exhibits><FAIR data><FAIR guiding principles><FAIR principles><Feedback><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Fixation><Functional disorder><Future><Gene Expression><Genes><Genetic><Genomic DNA><Genomics><Glucagon><Glukagon><Growth Hormone Inhibiting Factors><Growth Hormone-Inhibiting Hormone><Guanosine Cyclic Monophosphate><HG-Factor><Heterogeneity><Histologic><Histologically><Human><Humulin R><Hyperglycemic-Glycogenolytic Factor><IDDM><Image><Impairment><Individual><Infrastructure><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Investigators><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Leadership><MODY><Maturity-Onset Diabetes Mellitus><Measurement><Medical History><Medical Records><Metabolic><Metadata><Methodology><Modality><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Natural History><Neighborhoods><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Organ Donor><Organ Procurements><Oxygen Consumption><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Pathologic><Pathology><Personal Medical History><Personal Medical History Epidemiology><Phenotype><Physiologic><Physiological><Physiopathology><Population><Preparation><Process><Proteins><Publications><Quetelet index><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Research><Research Personnel><Research Resources><Researchers><Resolution><Resources><SRIH><SRIH-14><Scientific Publication><Single-Nucleus Sequencing><Slow-Onset Diabetes Mellitus><Somatostatin><Somatostatin-14><Somatotropin Release Inhibiting Factors><Somatotropin Release-Inhibiting Hormone><Sorting><Stable Diabetes Mellitus><Staining method><Stains><Sudden-Onset Diabetes Mellitus><Systematics><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><Visualization><adult onset diabetes><ages><attenuated insulin secretion><biobank><biorepository><blunted insulin secretion><cGMP><causation><clinical diagnosis><clinical phenotype><data access><data base><data deposition><data ecosystem><data harmonization><data integration><data interpretation><data portal><data resource><data sharing><data sharing ecosystem><data sharing portal><data submission><deceased donor><deceased organ donors><decreased insulin release><decreased insulin secretion><defective insulin secretion><demographics><diabetes><diminished insulin release><diminished insulin secretion><disease causation><disease heterogeneity><epigenomics><experience><gDNA><growth hormone release inhibiting factor><harmonized data><high dimensional data><human tissue><imaging><impaired insulin release><impaired insulin secretion><improved><inadequate insulin release><inadequate insulin secretion><indexing><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lowered insulin secretion><maturity onset diabetes><maturity onset diabetes in youth><maturity onset diabetes of the young><member><meta data><methylome><molecular phenotype><molecular profile><molecular signature><morphometry><multidimensional data><multidimensional datasets><multiomics><multiple omics><panomics><pathophysiology><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><posthumous donors><posthumous organ donor><preparations><programs><reduced insulin release><resolutions><response><response to therapy><response to treatment><sNuc-Seq><sample fixation><scATAC sequencing><scATAC-seq><single cell ATAC-seq><single cell ATAC-sequencing><single cell Assay for Transposase Accessible Chromatin sequencing><single cell sequencing assay for transposase accessible chromatin><single nucleus RNA-sequencing><single nucleus seq><single-cell Assay for Transposase-Accessible Chromatin with sequencing><single-cell assay for transposase-accessible chromatin using sequencing><single-cell assay for transposase-accessible chromatin-seq><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><suppressed insulin release><suppressed insulin secretion><therapeutic response><therapy response><tissue archive><transcriptome sequencing><transcriptomic sequencing><treatment response><treatment responsiveness><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><web site><website><whole slide imaging>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ali Naji

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$4,999,267

FY 2026

Project Title

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D)

Grant Number:

5U01DK123594-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2019

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D) Abstract Building on our existing infrastructure and scientific collaborations, and the expertise gained during the first four years of the HPAP effort for Type 2 Diabetes, we have assembled five cores with expertise ranging from pancrea...

Research Terms

<Adult-Onset Diabetes Mellitus><Age><Antidiabetic Hormone><Assay><B9 endocrine pancreas><BMI><BMI percentile><BMI z-score><Bioassay><Bioenergetics><Biological Assay><Biology><Blood><Blood Reticuloendothelial System><Body Tissues><Body mass index><Brittle Diabetes Mellitus><Calcium><Categories><Causality><Cell Body><Cell surface><Cells><Classification><Clinical Data><Collaborations><Communities><Cyclic GMP><Cyclic Somatostatin><Cytometry><DNA><DNA Sequence><Data><Data Analyses><Data Analysis><Data Bases><Data Discovery><Data Set><Databases><Deoxyribonucleic Acid><Detection><Diabetes Mellitus><Diagnosis><Disease><Disorder><Dysfunction><Endocrine Pancreas><Epidemic><Ethnic Origin><Ethnicity><Etiology><Evaluation><Exhibits><FAIR data><FAIR guiding principles><FAIR principles><Feedback><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Fixation><Functional disorder><Future><Gene Expression><Genes><Genetic><Genomic DNA><Genomics><Glucagon><Glukagon><Growth Hormone Inhibiting Factors><Growth Hormone-Inhibiting Hormone><Guanosine Cyclic Monophosphate><HG-Factor><Heterogeneity><Histologic><Histologically><Human><Humulin R><Hyperglycemic-Glycogenolytic Factor><IDDM><Image><Impairment><Individual><Infrastructure><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Investigators><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Leadership><MODY><Maturity-Onset Diabetes Mellitus><Measurement><Medical History><Medical Records><Metabolic><Metadata><Methodology><Modality><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Natural History><Neighborhoods><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Organ Donor><Organ Procurements><Oxygen Consumption><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Pathologic><Pathology><Personal Medical History><Personal Medical History Epidemiology><Phenotype><Physiologic><Physiological><Physiopathology><Population><Preparation><Process><Proteins><Publications><Quetelet index><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Research><Research Personnel><Research Resources><Researchers><Resolution><Resources><SRIH><SRIH-14><Scientific Publication><Single-Nucleus Sequencing><Slow-Onset Diabetes Mellitus><Somatostatin><Somatostatin-14><Somatotropin Release Inhibiting Factors><Somatotropin Release-Inhibiting Hormone><Sorting><Stable Diabetes Mellitus><Staining method><Stains><Sudden-Onset Diabetes Mellitus><Systematics><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><Visualization><adult onset diabetes><ages><attenuated insulin secretion><biobank><biorepository><blunted insulin secretion><cGMP><causation><clinical diagnosis><clinical phenotype><data access><data base><data deposition><data ecosystem><data harmonization><data integration><data interpretation><data portal><data resource><data sharing><data sharing ecosystem><data sharing portal><data submission><deceased donor><deceased organ donors><decreased insulin release><decreased insulin secretion><defective insulin secretion><demographics><diabetes><diminished insulin release><diminished insulin secretion><disease causation><disease heterogeneity><epigenomics><experience><gDNA><growth hormone release inhibiting factor><harmonized data><high dimensional data><human tissue><imaging><impaired insulin release><impaired insulin secretion><improved><inadequate insulin release><inadequate insulin secretion><indexing><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lowered insulin secretion><maturity onset diabetes><maturity onset diabetes in youth><maturity onset diabetes of the young><member><meta data><methylome><molecular phenotype><molecular profile><molecular signature><morphometry><multidimensional data><multidimensional datasets><multiomics><multiple omics><panomics><pathophysiology><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><posthumous donors><posthumous organ donor><preparations><programs><reduced insulin release><resolutions><response><response to therapy><response to treatment><sNuc-Seq><sample fixation><scATAC sequencing><scATAC-seq><single cell ATAC-seq><single cell ATAC-sequencing><single cell Assay for Transposase Accessible Chromatin sequencing><single cell sequencing assay for transposase accessible chromatin><single nucleus RNA-sequencing><single nucleus seq><single-cell Assay for Transposase-Accessible Chromatin with sequencing><single-cell assay for transposase-accessible chromatin using sequencing><single-cell assay for transposase-accessible chromatin-seq><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><suppressed insulin release><suppressed insulin secretion><therapeutic response><therapy response><tissue archive><transcriptome sequencing><transcriptomic sequencing><treatment response><treatment responsiveness><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><web site><website><whole slide imaging>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALVIN C POWERS

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$4,999,267

FY 2026

Project Title

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D)

Grant Number:

5U01DK123594-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2019

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D) Abstract Building on our existing infrastructure and scientific collaborations, and the expertise gained during the first four years of the HPAP effort for Type 2 Diabetes, we have assembled five cores with expertise ranging from pancrea...

Research Terms

<Adult-Onset Diabetes Mellitus><Age><Antidiabetic Hormone><Assay><B9 endocrine pancreas><BMI><BMI percentile><BMI z-score><Bioassay><Bioenergetics><Biological Assay><Biology><Blood><Blood Reticuloendothelial System><Body Tissues><Body mass index><Brittle Diabetes Mellitus><Calcium><Categories><Causality><Cell Body><Cell surface><Cells><Classification><Clinical Data><Collaborations><Communities><Cyclic GMP><Cyclic Somatostatin><Cytometry><DNA><DNA Sequence><Data><Data Analyses><Data Analysis><Data Bases><Data Discovery><Data Set><Databases><Deoxyribonucleic Acid><Detection><Diabetes Mellitus><Diagnosis><Disease><Disorder><Dysfunction><Endocrine Pancreas><Epidemic><Ethnic Origin><Ethnicity><Etiology><Evaluation><Exhibits><FAIR data><FAIR guiding principles><FAIR principles><Feedback><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Fixation><Functional disorder><Future><Gene Expression><Genes><Genetic><Genomic DNA><Genomics><Glucagon><Glukagon><Growth Hormone Inhibiting Factors><Growth Hormone-Inhibiting Hormone><Guanosine Cyclic Monophosphate><HG-Factor><Heterogeneity><Histologic><Histologically><Human><Humulin R><Hyperglycemic-Glycogenolytic Factor><IDDM><Image><Impairment><Individual><Infrastructure><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Investigators><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Leadership><MODY><Maturity-Onset Diabetes Mellitus><Measurement><Medical History><Medical Records><Metabolic><Metadata><Methodology><Modality><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Natural History><Neighborhoods><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Organ Donor><Organ Procurements><Oxygen Consumption><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Pathologic><Pathology><Personal Medical History><Personal Medical History Epidemiology><Phenotype><Physiologic><Physiological><Physiopathology><Population><Preparation><Process><Proteins><Publications><Quetelet index><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Research><Research Personnel><Research Resources><Researchers><Resolution><Resources><SRIH><SRIH-14><Scientific Publication><Single-Nucleus Sequencing><Slow-Onset Diabetes Mellitus><Somatostatin><Somatostatin-14><Somatotropin Release Inhibiting Factors><Somatotropin Release-Inhibiting Hormone><Sorting><Stable Diabetes Mellitus><Staining method><Stains><Sudden-Onset Diabetes Mellitus><Systematics><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><Visualization><adult onset diabetes><ages><attenuated insulin secretion><biobank><biorepository><blunted insulin secretion><cGMP><causation><clinical diagnosis><clinical phenotype><data access><data base><data deposition><data ecosystem><data harmonization><data integration><data interpretation><data portal><data resource><data sharing><data sharing ecosystem><data sharing portal><data submission><deceased donor><deceased organ donors><decreased insulin release><decreased insulin secretion><defective insulin secretion><demographics><diabetes><diminished insulin release><diminished insulin secretion><disease causation><disease heterogeneity><epigenomics><experience><gDNA><growth hormone release inhibiting factor><harmonized data><high dimensional data><human tissue><imaging><impaired insulin release><impaired insulin secretion><improved><inadequate insulin release><inadequate insulin secretion><indexing><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lowered insulin secretion><maturity onset diabetes><maturity onset diabetes in youth><maturity onset diabetes of the young><member><meta data><methylome><molecular phenotype><molecular profile><molecular signature><morphometry><multidimensional data><multidimensional datasets><multiomics><multiple omics><panomics><pathophysiology><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><posthumous donors><posthumous organ donor><preparations><programs><reduced insulin release><resolutions><response><response to therapy><response to treatment><sNuc-Seq><sample fixation><scATAC sequencing><scATAC-seq><single cell ATAC-seq><single cell ATAC-sequencing><single cell Assay for Transposase Accessible Chromatin sequencing><single cell sequencing assay for transposase accessible chromatin><single nucleus RNA-sequencing><single nucleus seq><single-cell Assay for Transposase-Accessible Chromatin with sequencing><single-cell assay for transposase-accessible chromatin using sequencing><single-cell assay for transposase-accessible chromatin-seq><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><suppressed insulin release><suppressed insulin secretion><therapeutic response><therapy response><tissue archive><transcriptome sequencing><transcriptomic sequencing><treatment response><treatment responsiveness><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><web site><website><whole slide imaging>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DORIS A STOFFERS

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$4,999,267

FY 2026

Project Title

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D)

Grant Number:

5U01DK123594-07

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2019

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D) Abstract Building on our existing infrastructure and scientific collaborations, and the expertise gained during the first four years of the HPAP effort for Type 2 Diabetes, we have assembled five cores with expertise ranging from pancrea...

Research Terms

<Adult-Onset Diabetes Mellitus><Age><Antidiabetic Hormone><Assay><B9 endocrine pancreas><BMI><BMI percentile><BMI z-score><Bioassay><Bioenergetics><Biological Assay><Biology><Blood><Blood Reticuloendothelial System><Body Tissues><Body mass index><Brittle Diabetes Mellitus><Calcium><Categories><Causality><Cell Body><Cell surface><Cells><Classification><Clinical Data><Collaborations><Communities><Cyclic GMP><Cyclic Somatostatin><Cytometry><DNA><DNA Sequence><Data><Data Analyses><Data Analysis><Data Bases><Data Discovery><Data Set><Databases><Deoxyribonucleic Acid><Detection><Diabetes Mellitus><Diagnosis><Disease><Disorder><Dysfunction><Endocrine Pancreas><Epidemic><Ethnic Origin><Ethnicity><Etiology><Evaluation><Exhibits><FAIR data><FAIR guiding principles><FAIR principles><Feedback><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Fixation><Functional disorder><Future><Gene Expression><Genes><Genetic><Genomic DNA><Genomics><Glucagon><Glukagon><Growth Hormone Inhibiting Factors><Growth Hormone-Inhibiting Hormone><Guanosine Cyclic Monophosphate><HG-Factor><Heterogeneity><Histologic><Histologically><Human><Humulin R><Hyperglycemic-Glycogenolytic Factor><IDDM><Image><Impairment><Individual><Infrastructure><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Investigators><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Leadership><MODY><Maturity-Onset Diabetes Mellitus><Measurement><Medical History><Medical Records><Metabolic><Metadata><Methodology><Modality><Modern Man><Molecular><Molecular Fingerprinting><Molecular Profiling><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Natural History><Neighborhoods><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Organ Donor><Organ Procurements><Oxygen Consumption><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Pathologic><Pathology><Personal Medical History><Personal Medical History Epidemiology><Phenotype><Physiologic><Physiological><Physiopathology><Population><Preparation><Process><Proteins><Publications><Quetelet index><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Research><Research Personnel><Research Resources><Researchers><Resolution><Resources><SRIH><SRIH-14><Scientific Publication><Single-Nucleus Sequencing><Slow-Onset Diabetes Mellitus><Somatostatin><Somatostatin-14><Somatotropin Release Inhibiting Factors><Somatotropin Release-Inhibiting Hormone><Sorting><Stable Diabetes Mellitus><Staining method><Stains><Sudden-Onset Diabetes Mellitus><Systematics><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><Visualization><adult onset diabetes><ages><attenuated insulin secretion><biobank><biorepository><blunted insulin secretion><cGMP><causation><clinical diagnosis><clinical phenotype><data access><data base><data deposition><data ecosystem><data harmonization><data integration><data interpretation><data portal><data resource><data sharing><data sharing ecosystem><data sharing portal><data submission><deceased donor><deceased organ donors><decreased insulin release><decreased insulin secretion><defective insulin secretion><demographics><diabetes><diminished insulin release><diminished insulin secretion><disease causation><disease heterogeneity><epigenomics><experience><gDNA><growth hormone release inhibiting factor><harmonized data><high dimensional data><human tissue><imaging><impaired insulin release><impaired insulin secretion><improved><inadequate insulin release><inadequate insulin secretion><indexing><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lowered insulin secretion><maturity onset diabetes><maturity onset diabetes in youth><maturity onset diabetes of the young><member><meta data><methylome><molecular phenotype><molecular profile><molecular signature><morphometry><multidimensional data><multidimensional datasets><multiomics><multiple omics><panomics><pathophysiology><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><posthumous donors><posthumous organ donor><preparations><programs><reduced insulin release><resolutions><response><response to therapy><response to treatment><sNuc-Seq><sample fixation><scATAC sequencing><scATAC-seq><single cell ATAC-seq><single cell ATAC-sequencing><single cell Assay for Transposase Accessible Chromatin sequencing><single cell sequencing assay for transposase accessible chromatin><single nucleus RNA-sequencing><single nucleus seq><single-cell Assay for Transposase-Accessible Chromatin with sequencing><single-cell assay for transposase-accessible chromatin using sequencing><single-cell assay for transposase-accessible chromatin-seq><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><suppressed insulin release><suppressed insulin secretion><therapeutic response><therapy response><tissue archive><transcriptome sequencing><transcriptomic sequencing><treatment response><treatment responsiveness><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><web site><website><whole slide imaging>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ionut Bebu

GEORGE WASHINGTON UNIVERSITY, WASHINGTON, DC

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$3,588,179

FY 2026

Project Title

Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes - Biostatistics Research Center

Grant Number:

5U01DK134971-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

(<30 lines) Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resist...

Research Terms

<0-11 years old><Active Follow-up><Address><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Agreement><Approaches to prevention><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Business-Friendly Atmosphere><Case Report Form><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Certification><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Communication><Complications of Diabetes Mellitus><Conflict of Interest><Consent><Coupled><Creativeness><Data><Deterioration><Development><Devices><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Disease><Disorder><Dysfunction><Enrollment><Ensure><Epidemiology><Event><Functional disorder><Funding><Future><Genetic Materials><Geography><Goals><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Investigators><Ketosis-Resistant Diabetes Mellitus><Laboratories><Leadership><Logistics><Manuals><Manuscripts><Maturity-Onset Diabetes Mellitus><Mediator><Metabolic><Methodology><Methods><Monitor><Multi-center studies><Multicenter Studies><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obesity Epidemic><Observational Study><Onset of illness><Participant><Pathogenesis><Performance><Persons><Phase><Phenotype><Physiologic><Physiological><Physiology><Physiopathology><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Privatization><Procedures><Process><Protocol><Protocols documentation><Puberty><Publications><Qualifying><Quality Control><Randomization trial><Reporting><Research><Research Design><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Factors><Rural><Safety><Sampling><Scientific Publication><Sedentary behavior><Sedentary life-style><Serious Adverse Event><Severe Adverse Event><Site><Slow-Onset Diabetes Mellitus><Specific qualifier value><Specified><Stable Diabetes Mellitus><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Statistical Methods><Study Type><Subcellular Process><System><T2 DM><T2D><T2DM><Training><Translating><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Validation><Washington><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><blood glucose regulation><boys><business-friendly environment><clinical research site><clinical site><cohort><collaborative atmosphere><collaborative environment><corpulence><creativity><data exchange><data management><data transfer><data transmission><depository><design><designing><developmental><diabetes><diabetes control><diabetes mellitus control><diabetes prevention program><diabetes risk><disease onset><disorder onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><high risk><improved><innovate><innovation><innovative><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><juvenile><juvenile human><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><meeting><meetings><modifiable risk><multidisciplinary><novel><observational research study><observational survey><operation><operations><pathophysiology><pediatric><peer-group atmosphere><peer-group environment><phase 2 study><phase II study><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary outcome><programs><progression risk><psychologic><psychological><quality assurance><randomized trial><recruit><repository><response><secondary outcome><sedentary lifestyle><serious adverse experience><serious adverse reaction><social><statistic methods><statistical analysis><study design><success><therapeutic target><timeline><treatment strategy><type 2 DM><type II DM><type two diabetes><user-friendly><validations><virtual><web site><website><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Barbara Halina Braffett

GEORGE WASHINGTON UNIVERSITY, WASHINGTON, DC

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$3,588,179

FY 2026

Project Title

Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes - Biostatistics Research Center

Grant Number:

5U01DK134971-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

(<30 lines) Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resist...

Research Terms

<0-11 years old><Active Follow-up><Address><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Agreement><Approaches to prevention><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Business-Friendly Atmosphere><Case Report Form><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Certification><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Communication><Complications of Diabetes Mellitus><Conflict of Interest><Consent><Coupled><Creativeness><Data><Deterioration><Development><Devices><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Disease><Disorder><Dysfunction><Enrollment><Ensure><Epidemiology><Event><Functional disorder><Funding><Future><Genetic Materials><Geography><Goals><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Investigators><Ketosis-Resistant Diabetes Mellitus><Laboratories><Leadership><Logistics><Manuals><Manuscripts><Maturity-Onset Diabetes Mellitus><Mediator><Metabolic><Methodology><Methods><Monitor><Multi-center studies><Multicenter Studies><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obesity Epidemic><Observational Study><Onset of illness><Participant><Pathogenesis><Performance><Persons><Phase><Phenotype><Physiologic><Physiological><Physiology><Physiopathology><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Privatization><Procedures><Process><Protocol><Protocols documentation><Puberty><Publications><Qualifying><Quality Control><Randomization trial><Reporting><Research><Research Design><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Factors><Rural><Safety><Sampling><Scientific Publication><Sedentary behavior><Sedentary life-style><Serious Adverse Event><Severe Adverse Event><Site><Slow-Onset Diabetes Mellitus><Specific qualifier value><Specified><Stable Diabetes Mellitus><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Statistical Methods><Study Type><Subcellular Process><System><T2 DM><T2D><T2DM><Training><Translating><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Validation><Washington><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><blood glucose regulation><boys><business-friendly environment><clinical research site><clinical site><cohort><collaborative atmosphere><collaborative environment><corpulence><creativity><data exchange><data management><data transfer><data transmission><depository><design><designing><developmental><diabetes><diabetes control><diabetes mellitus control><diabetes prevention program><diabetes risk><disease onset><disorder onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><high risk><improved><innovate><innovation><innovative><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><juvenile><juvenile human><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><meeting><meetings><modifiable risk><multidisciplinary><novel><observational research study><observational survey><operation><operations><pathophysiology><pediatric><peer-group atmosphere><peer-group environment><phase 2 study><phase II study><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary outcome><programs><progression risk><psychologic><psychological><quality assurance><randomized trial><recruit><repository><response><secondary outcome><sedentary lifestyle><serious adverse experience><serious adverse reaction><social><statistic methods><statistical analysis><study design><success><therapeutic target><timeline><treatment strategy><type 2 DM><type II DM><type two diabetes><user-friendly><validations><virtual><web site><website><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Scott Soleimanpour

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$1,198,802

FY 2026

Project Title

Michigan Diabetes Research Center (MDRC)

Grant Number:

5P30DK020572-49

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/1/1996

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

MDRC Center Overview Project Summary/Abstract The mission of the MDRC is to promote new discoveries and enhance scientific progress in diabetes, its complications, and related metabolic disorders through the support of cutting-edge basic and clinical research by its highly interactive research base....

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Elizabeth T Jensen

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$1,003,076

FY 2026

Project Title

Illuminating the path(ophysiology) to development of youth-onset type 2 diabetes (PATH-NC)

Grant Number:

5U01DK134967-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/22/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

(<30 lines) Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resist...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Age><Ancillary Study><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Children (0-21)><Collaborations><Consensus><Continuous Glucose Monitor><Coupled><Deterioration><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiology><Event><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Health Sciences><Health system><Hemoglobin A(1)><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Modeling><NIDDM><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><North Carolina><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Overweight><Pathogenesis><Patient Recruitments><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><Publications><QOL><Quality Control><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Rural Community><SEARCH for Diabetes in Youth><Sampling><Scientific Publication><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><T2 DM><T2D><T2DM><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Urban Community><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><atrium><biobank><biorepository><blood glucose regulation><boys><cohort><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><health science research><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><medical college><medical schools><modifiable risk><nine year old><nine years of age><novel><participant recruitment><pathophysiology><patient population><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><school of medicine><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><therapeutic target><timeline><treatment strategy><type 2 DM><type II DM><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christine B. Turley

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

High-opportunity lead · 80/100

Likely hiring

Large award

Recent

Active award

$1,003,076

FY 2026

Project Title

Illuminating the path(ophysiology) to development of youth-onset type 2 diabetes (PATH-NC)

Grant Number:

5U01DK134967-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/22/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

(<30 lines) Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resist...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Age><Ancillary Study><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Children (0-21)><Collaborations><Consensus><Continuous Glucose Monitor><Coupled><Deterioration><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiology><Event><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Health Sciences><Health system><Hemoglobin A(1)><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Modeling><NIDDM><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><North Carolina><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Overweight><Pathogenesis><Patient Recruitments><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><Publications><QOL><Quality Control><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Rural Community><SEARCH for Diabetes in Youth><Sampling><Scientific Publication><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><T2 DM><T2D><T2DM><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Urban Community><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><atrium><biobank><biorepository><blood glucose regulation><boys><cohort><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><health science research><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><medical college><medical schools><modifiable risk><nine year old><nine years of age><novel><participant recruitment><pathophysiology><patient population><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><school of medicine><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><therapeutic target><timeline><treatment strategy><type 2 DM><type II DM><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dana Dabelea

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$967,925

FY 2026

Project Title

Understanding the Pathophysiology of Type 2 Diabetes in Navajo Youth

Grant Number:

5U01DK134981-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

(<30 lines) Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resist...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Age><Ancillary Study><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Children (0-21)><Collaborations><Colorado><Consensus><Continuous Glucose Monitor><Coupled><Deterioration><Development><Diabetes Mellitus><Diabetes prevention><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiology><Event><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Life course epidemiology><Lifecourse epidemiology><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Modeling><NIDDM><Navaho><Navajo><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Outcome Study><Overweight><Pathogenesis><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><SEARCH for Diabetes in Youth><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><T2 DM><T2D><T2DM><Time><Tribes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><biobank><biorepository><blood glucose regulation><boys><cohort><community engagement><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><effective therapy><effective treatment><engagement with communities><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><member><modifiable risk><nine year old><nine years of age><novel><pathophysiology><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><therapeutic target><timeline><treatment strategy><tribal Nation><tribal governance><tribal government><tribal self-governance><type 2 DM><type II DM><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Wei Perng

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$967,925

FY 2026

Project Title

Understanding the Pathophysiology of Type 2 Diabetes in Navajo Youth

Grant Number:

5U01DK134981-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

(<30 lines) Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resist...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Age><Ancillary Study><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Children (0-21)><Collaborations><Colorado><Consensus><Continuous Glucose Monitor><Coupled><Deterioration><Development><Diabetes Mellitus><Diabetes prevention><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiology><Event><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Life course epidemiology><Lifecourse epidemiology><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Modeling><NIDDM><Navaho><Navajo><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Outcome Study><Overweight><Pathogenesis><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><SEARCH for Diabetes in Youth><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><T2 DM><T2D><T2DM><Time><Tribes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><biobank><biorepository><blood glucose regulation><boys><cohort><community engagement><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><effective therapy><effective treatment><engagement with communities><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><member><modifiable risk><nine year old><nine years of age><novel><pathophysiology><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><therapeutic target><timeline><treatment strategy><tribal Nation><tribal governance><tribal government><tribal self-governance><type 2 DM><type II DM><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jeremy H Pettus

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$879,491

FY 2026

Project Title

Using technology to define and mitigate risk of impaired awareness of hypoglycemia in patients with type 1 diabetes

Grant Number:

5U01DK135121-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2022

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ ABSTRACT Severe hypoglycemia remains a common and life-threatening issue for patients living with type 1 diabetes (T1D). Research has consistently shown that patients with impaired awareness of hypoglycemia (IAH), which typically coexists with a diminished counterregulatory response...

Research Terms

<18 year old><18 years of age><Active Follow-up><Address><Adrenaline><Awareness><Blinded><Blood Glucose><Blood Plasma><Blood Sugar><Brittle Diabetes Mellitus><C-Peptide><Caring><Clampings><Clinical><Clinical Trials><Closure by clamp><Continuous Glucose Monitor><D-Glucose><Data><Day Blindness><Dextrose><Diabetes Mellitus><Endocrine Gland Secretion><Enrollment><Epinephrine><Glucose><Goals><Gold><Hemeralopias><Heterogeneity><Hormones><Hospital Admission><Hospitalization><Hour><Humulin R><Hybrids><Hyperinsulinemia><Hyperinsulinism><Hypoglycemia><IDDM><Impairment><Individual><Insulin><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intervention><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Life><Methods><Modernization><Novolin R><Outcome><Patients><Plasma><Plasma Serum><Questionnaires><Randomized><Regular Insulin><Research><Research Design><Reticuloendothelial System, Serum, Plasma><Risk><Risk Reduction><Safety><Study Type><Sudden-Onset Diabetes Mellitus><Symptoms><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Therapeutic Epinephrine><Therapeutic Hormone><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><active followup><age 18><age 18 years><arm><clinical practice><cohort><connecting peptide><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><counterregulation><diabetes><diabetes management><diabetes mellitus management><diabetic management><eighteen year old><eighteen years of age><enroll><experience><follow up><follow-up><followed up><followup><high risk><hypoglycemia unawareness><hypoglycemic><hypoglycemic episodes><improved><inclusion criteria><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><novel><primary outcome><randomisation><randomization><randomly assigned><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk mitigation><risk-reducing><safe patient><screening><screenings><standard of care><study design><tool><type I diabetes><type one diabetes>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ben Steven Gerber

UNIV OF MASSACHUSETTS MED SCH WORCESTER, WORCESTER, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$851,044

FY 2026

Project Title

Team Support to Improve Glycemic Control Using CGM in Diverse Populations (TEAM CGM)

Grant Number:

5R01DK133265-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/5/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Continuous glucose monitoring (CGM) has demonstrable benefits for people living with diabetes, including improvement in diabetes control and reduction in hypoglycemia. Randomized controlled trials have demonstrated that CGM can reduce hemoglobin A1c (HbA1c) and increase in the time i...

Research Terms

<0-11 years old><Address><Adoption><Adult-Onset Diabetes Mellitus><Affect><Behavioral><Black><Black race><Blood Glucose><Blood Sugar><Brittle Diabetes Mellitus><California><Caring><Child><Child Youth><Children (0-21)><Clinical Pharmacists><Community Health Aides><Community Health Centers><Continuous Glucose Monitor><D-Glucose><Dextrose><Diabetes Mellitus><Disparities><Disparity><Family Practice><Future><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Systems><Hemoglobin A(1)><Hispanic><Humulin R><Hyperglycemia><Hypoglycemia><IDDM><Individual><Individuals from minority><Individuals of minority><Infusion><Infusion procedures><Injections><Insulin><Insulin-Dependent Diabetes Mellitus><Insurance><Intercellular Fluid><Interstitial Fluids><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Low Income Population><Low income><Low income group><Massachusetts><Maturity-Onset Diabetes Mellitus><Measures><Minority Groups><Minority People><Minority Population><Minority individual><Modeling><NIDDM><Neighborhood Health Center><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Novolin R><Observational Study><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Persons><Pharmacists><Population><Population Heterogeneity><Primary Care><QOL><Quality of life><RE-AIM><Randomized><Randomized, Controlled Trials><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Regular Insulin><Research><Research Design><Research Resources><Resources><Self Management><Sequential Multiple Assignment Randomized Trial><Slow-Onset Diabetes Mellitus><Specialist><Stable Diabetes Mellitus><Study Type><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Time><Translations><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States><Upper arm><Variant><Variation><Vulnerable Populations><Work><adult onset diabetes><adult youth><assess effectiveness><cardiovascular risk><cardiovascular risk factor><community health worker><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><cost effective><cost effectiveness><cost estimate><cost estimation><determine effectiveness><diabetes><diabetes control><diabetes management><diabetes mellitus control><diabetes mellitus management><diabetic management><differences due to race><differences in race><differs by race><differs in race><diverse populations><drug adherence><drug compliance><effectiveness assessment><effectiveness evaluation><effectiveness study><ethnic difference><ethnicity difference><evaluate effectiveness><examine effectiveness><family medicine><glycemic control><health care organization><health care service organization><hemoglobin A1c><heterogeneous population><hyperglycemic><hypoglycemic><hypoglycemic episodes><improved><infusions><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><kids><large data sets><large datasets><low income individual><low income people><m-Health><mHealth><maturity onset diabetes><medication adherence><medication compliance><minority communities><mobile health><monitoring device><observational research study><observational survey><patient oriented outcomes><patient population><population diversity><primary care provider><primary care setting><providers from primary care><providers of primary care><race based differences><race differences><race related differences><racial difference><racially different><randomisation><randomization><randomized control trial><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><secondary outcome><sensor><social health determinants><study design><subcutaneous><subdermal><telehealth><tool><translation><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><vulnerable group><vulnerable individual><vulnerable people><young adult><young adult age><young adulthood><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kelseanna Hollis-Hansen

TUFTS UNIVERSITY BOSTON, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$838,493

FY 2026

Project Title

Optimizing interventions to improve nutrition security and reduce diabetes risk among food pantry clients

Grant Number:

1R01DK145891-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Food insecurity is associated with insufficient nutrient intake, 2-3 times greater risk for diabetes, and suboptimal glycemic control. Over 50 million people in the US rely on food banks and pantries to prevent or alleviate food insecurity. To address disparities in diet-related dise...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alessandro Doria

JOSLIN DIABETES CENTER, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$828,756

FY 2026

Project Title

Early myocardial remodeling and progressive kidney function decline in type 1 diabetes

Grant Number:

5R01HL161858-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/24/2021

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY A large proportion of the excess CVD morbidity and mortality experienced by individuals with T1D occur in conjunction with diabetic kidney disease (DKD), which is associated with a striking increase in the risk of coronary artery disease (CAD) and heart failure. The latter is frequently due ...

Research Terms

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ELIZABETH R. SEAQUIST

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$826,620

FY 2026

Project Title

University of Minnesota Clinical Center for the Restoration of Impaired Awareness of Hypoglycemia in Type 1 Diabetes

Grant Number:

5U01DK135130-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2022

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Hypoglycemia (HG) is common in the lives of people with type 1 diabetes (T1D) and may prevent them from achieving the benefits associated with optimal glycemic control. Recurrent HG over a few days to weeks may lead to the condition of impaired awareness of HG (IAH) where the first sign of a low blo...

Research Terms

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Jeanie Beatrice Tryggestad

UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OKLAHOMA CITY, OK

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$825,450

FY 2026

Project Title

Identifying Metabolic and Psychosocial Antecedents and Characteristics of youth-onset Type 2 diabetes (IMPACT DM)

Grant Number:

5U01DK135007-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/23/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><9 year old><9 years of age><Abdominal obesity><Active Follow-up><Address><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Aeroseb-HC><Affect><Age><Algorithms><Android fat distribution><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Biometrics><Biometry><Biostatistics><Blood Pressure><Blood Serum><Body Composition><Body mass index><C-Peptide><Catchment Area><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Center for Translational Science Activities><Central obesity><Centripetal obesity><Cetacort><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Children's Hospital><Chronic stress><Clinic><Clinical><Collaborations><Colorado><Complications of Diabetes Mellitus><Consensus><Continuous Glucose Monitor><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Coupled><D-Glucose><D-Isoglucosamine><Dermacort><Development><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diagnosis><Diet><Disease><Disease Progression><Disorder><Dysfunction><Early identification><Eldecort><Endocrine Gland Secretion><Energy Expenditure><Energy Metabolism><Enrollment><Environment><Epidemiology><Ethnic Origin><Ethnicity><Event><Exposure to><Failure><Family><Family Medical History><Family Medical History Epidemiology><Family history of><Fats><Fatty acid glycerol esters><Feedback><Free Fatty Acids><Fructosamine><Functional disorder><Funding><Future><GI microbiome><Genetic Materials><Geography><Gestation><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><HDL Cholesterol><HDL Cholesterol Lipoproteins><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Hemoglobin A(1)><High Density Lipoprotein Cholesterol><Hispanic><Hispanic Americans><History><Hormones><Hour><Humulin R><Hydrocortisone><Hydrocortone><Hypertension><Hytone><IRB><IRBs><Infrastructure><Institutional Review Boards><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Latino><Leadership><Life Style><Lifestyle><Maturity-Onset Diabetes Mellitus><Measurable><Measures><Mediating><Medical><Medical History><Medicine><Mental Depression><Metabolic><MicroRNAs><Microvascular Dysfunction><Modeling><NIDDK><NIDDM><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Native American group><Native American individual><Native American people><Native American population><Native Americans><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nutracort><OGTT><Obesity><Obesity Epidemic><Oklahoma><Onset of illness><Oral Glucose Tolerance Test><Overweight><Pancreas><Pancreatic><Participant><Patient Recruitments><Pattern><Pediatric Hospitals><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Position><Positioning Attribute><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Value><Pregnancy><Prevalence><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Proctocort><Proinsulin><Proteins><Protocol><Protocols documentation><Provider><Psychosocial Factor><Psychosocial Stress><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Recording of previous events><Records><Regression Analyses><Regression Analysis><Regression Diagnostics><Regular Insulin><Reporting><Research><Research Personnel><Researchers><Rest><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Salivary><Sampling><Serum><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Statistical Regression><Stress><Subcellular Process><T2 DM><T2D><T2DM><Testing><Therapeutic Hormone><Time><Translational Research><Translational Science><Truncal obesity><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Universities><Urban Population><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Visit><Youth><Youth 10-21><active followup><adipocytokines><adipokines><adiposity><adolescent minority><adult onset diabetes><adverse childhood events><adverse childhood experiences><age 9><age 9 years><ages><alpha-Lipoprotein Cholesterol><at risk behavior><bio-markers><biobank><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><boys><cardiometabolic><cardiometabolism><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical translation><clinically translatable><cohort><computer based prediction><connecting peptide><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><cytokine><demographics><depression><deprivation><design><designing><developmental><diabetes><diabetes risk><diets><digestive tract microbiome><disease onset><disorder onset><effective therapy><effective treatment><enroll><enteric microbiome><epidemiologic><epidemiological><exercise capacity><experience><exposed in utero><fasting glucose><fetal exposure><follow up><follow-up><followed up><followup><gastrointestinal microbiome><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><gut microbiome><gut-associated microbiome><hemoglobin A1c><high blood pressure><high risk><histories><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><impaired glucose tolerance><improved><in utero><in utero exposure><indexing><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><intestinal biome><intestinal microbiome><intra-uterine environmental exposure><intrauterine environmental exposure><juvenile><juvenile human><ketosis resistant diabetes><kids><malleable risk><maternal adiposity><maternal obesity><maturity onset diabetes><miRNA><microvascular complications><microvascular disease><minority children><minority youth><modifiable risk><new marker><nine year old><nine years of age><novel><novel biomarker><novel marker><obese children><obesity during childhood><obesity in children><obesity intervention><obesity therapy><obesity treatment><participant recruitment><pathophysiology><patient population><patient retention><pediatric><pediatric minority><pediatric obesity><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><predictive modeling><prenatal exposure><prenatally exposed><preservation><prevent><preventing><primary care practice><primary end point><primary endpoint><programs><progression risk><psychologic><psychological><psychosocial><psychosocial stresses><psychosocial stressors><psychosocial variables><public health relevance><racial minority><recruit><rural patients><safety net><screening><screenings><secondary end point><secondary endpoint><social><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><specimen bank><specimen repository><success><therapeutic target><therapy optimization><timeline><translation research><translational investigation><translational research center><translational sciences center><treatment optimization><treatment program><treatment strategy><type 2 DM><type II DM><type two diabetes><urban group><urban individual><urban people><visceral obesity><young minority><youngster><youth age><β-cell><β-cells><βCell>

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AMY SANGHAVI SHAH

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$824,771

FY 2026

Project Title

Cincinnati Children's Clinical Center for Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes

Grant Number:

5U01DK134976-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

(<30 lines) Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resist...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Advertisement><Advertisements><Age><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Children's Hospital><Clinic><Collaborations><Communities><Consensus><Continuous Glucose Monitor><Coupled><Deterioration><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiology><Event><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical><Medical History><Medical center><Metabolic><Modeling><NIDDM><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><OGTT><Obesity><Obesity Epidemic><Onset of illness><Operative Procedures><Operative Surgical Procedures><Oral Glucose Tolerance Test><Overweight><Pathogenesis><Pediatric Hospitals><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><SEARCH for Diabetes in Youth><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><Surgical><Surgical Interventions><Surgical Procedure><T2 DM><T2D><T2DM><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><biobank><biorepository><blood glucose regulation><boys><clinical center><co-morbid><co-morbidity><cohort><comorbidity><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><modifiable risk><nine year old><nine years of age><novel><pathophysiology><pediatric><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><surgery><therapeutic target><timeline><treatment strategy><type 2 DM><type II DM><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Randi Kay Johnson

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$797,416

FY 2026

Project Title

Immunogenetics in the viral etiology and pathogenesis of type 1 diabetes

Grant Number:

1R01DK143181-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Type 1 diabetes (T1D) results from a misdirected immune response, and its incidence has been increasing globally for decades. Viral infection, particularly with enterovirus, is a leading candidate trigger for the initiation and progression of islet cell destruction that ultimately re...

Research Terms

<0-11 years old><21+ years old><Acceleration><Adult><Adult Human><Affect><Algorithms><Autoantibodies><Autoimmune Diseases><Autoimmune Status><Autoimmunity><B9 endocrine pancreas><Bioinformatics><Brittle Diabetes Mellitus><Catalogs><Causality><Cell Body><Cells><Cellular Immune Function><Child><Child Youth><Children (0-21)><Clinical><Complement><Complement Activation><Complement Proteins><Complex><Cytotoxic cell><Data><Data Bases><Databases><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Endocrine Pancreas><Enterovirus><Enterovirus Infections><Epidemiologic Research><Etiology><Expenditure><Exposure Assessment><Functional Metagenomics><Genes><Genetic><Genetic Diversity><Genetic Variation><Genomic Segment><Goals><Heterogeneity><Histocompatibility Complex><Histocompatibility Complices><Human><IDDM><Immune><Immune Cell Activation><Immune Globulins><Immune response><Immunes><Immunity><Immunogenetics><Immunoglobulins><Incidence><Infection><Inflammatory Response><Innate Immune Response><Insulin-Dependent Diabetes Mellitus><Investigation><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><K Cells><K lymphocyte><Ketosis-Prone Diabetes Mellitus><Killer Cells><Knowledge><Long-term infection><MHC Receptor><Major Histocompatibility Complex><Major Histocompatibility Complex Receptor><Major Histocompatibility Complices><Measurement><Measures><Metagenomics><Methods><Mice><Mice Mammals><Modern Man><Murine><Mus><NK Cells><Natural History><Natural Killer Cells><Nesidioblasts><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Phase><Predisposition><Preventative strategy><Prevention strategy><Prevention trial><Preventive strategy><Primary Prevention><Receptor Protein><Recovery><Resolution><Risk><Role><Sample Size><Sampling><Structure><Sudden-Onset Diabetes Mellitus><Susceptibility><T-Cell Antigen Receptors><T-Cell Receptor><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Vaccines><Variant><Variation><Viral><Viral Diseases><Virus><Virus Diseases><Youth><Youth 10-21><acute infection><adaptive immune response><adulthood><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><case control><case-controlled><catalog><causation><chronic infection><clinical diagnosis><cohort><combinatorial><complement pathway regulation><complement system><complementation><cost effective><data base><design><designing><developmental><diabetes><diabetes pathogenesis><diabetes risk><disease causation><endocrine pancreas development><epidemiologic investigation><exposure analysis><exposure evaluation><exposure measurement><exposure profiling><exposure survey><fecal sample><gene complementation><genome segment><genomic region><high risk group><high risk individual><high risk people><high risk population><high throughput technology><host response><immune activation><immune function><immune system response><immunoresponse><infection risk><inflammation marker><inflammatory marker><insight><insulin dependent diabetes><insulin dependent type 1><investigate epidemiology><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><killer immunoglobulin-like receptor><multidisciplinary><novel><persistent infection><prevent><preventing><prospective><receptor><resolutions><response><self reactive antibody><social role><stool sample><stool specimen><study epidemiology><survey epidemiology><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic agent development><therapeutic development><type I diabetes><type one diabetes><viral infection><virus infection><virus-induced disease><youngster><youth age>

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SIMON J FISHER

UNIVERSITY OF KENTUCKY, LEXINGTON, KY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$790,957

FY 2026

Project Title

Restoration of Impaired Awareness of Hypoglycemia U01 Consortium: University of Kentucky

Grant Number:

5U01DK135111-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2022

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

“Restoration of Impaired Awareness of Hypoglycemia U01 Consortium: University of Kentucky” Abstract For insulin-treated people with Type 1 Diabetes (T1D), hypoglycemia is the rate limiting step in their goals to appropriately control their blood sugar and avoid long-term diabetes complications. Unfo...

Research Terms

<21+ years old><Active Follow-up><Adult><Adult Human><Age><Applications Grants><Awareness><Blood Glucose><Blood Sugar><Brittle Diabetes Mellitus><Caring><Clampings><Clinical Research><Clinical Study><Closure by clamp><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Cooperative Agreements><Coupled><D-Glucose><Development><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Education><Educational aspects><Endocrine Gland Secretion><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Event><Failure><Frequencies><Glucose><Glucose Clamp><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Grant Proposals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><Heterogeneity><Hormones><Humulin R><Hybrids><Hyperinsulinemic Clamp><Hypoglycemia><IDDM><Impairment><Individual><Infrastructure><Institution><Insulin><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intervention><Juvenile-Onset Diabetes Mellitus><Kentucky><Ketosis-Prone Diabetes Mellitus><Leadership><Life><Measurement><Measures><Metabolic><Methodology><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Novolin R><Pathologic Processes><Pathological Processes><Patient Self-Report><Patients><Persons><Physiologic><Physiological><Play><Questionnaires><R-Series Research Projects><R01 Mechanism><R01 Program><Recurrence><Recurrent><Regular Insulin><Research><Research Grants><Research Project Grants><Research Projects><Risk><Role><Rural><Self-Report><Severities><Site><Study Subject><Sudden-Onset Diabetes Mellitus><Symptoms><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Therapeutic Hormone><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><U-Series Cooperative Agreements><Universities><active followup><adulthood><ages><burden of disease><burden of illness><clinical research site><clinical site><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><counterregulation><developmental><diabetes><disease burden><experience><follow up><follow-up><followed up><followup><hemoglobin A1c><hypoglycemic><hypoglycemic episodes><improved><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><new approaches><novel><novel approaches><novel strategies><novel strategy><recruit><response><restoration><social role><type I diabetes><type one diabetes>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mary Patricia Gallagher

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$780,219

FY 2026

Project Title

Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes- NYU Clinical Center

Grant Number:

5U01DK135012-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/17/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Age><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Brittle Diabetes Mellitus><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Children (0-21)><Collaborations><Community Outreach><Complications of Diabetes Mellitus><Consensus><Continuous Glucose Monitor><Coupled><Data Systems><Deterioration><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiologic Research><Epidemiology><Espanol><Event><Feedback><Follow-Up Studies><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IDDM><IRB><IRBs><IT Systems><Incidence><Information Systems><Information Technology Systems><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intention><Intervention><Intervention Studies><Investigation><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Long Island><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Modeling><NIDDM><Natural History><Neighborhoods><Neurocognitive><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Outcome><Overweight><Pathogenesis><Pathway interactions><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Spanish><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><bilingual><bilingualism><biobank><biorepository><blood glucose regulation><boys><clinical center><cohort><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes control><diabetes mellitus control><diabetes risk><diets><disease onset><disorder onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiologic investigation><epidemiological><experience><follow up><follow-up><follow-up research study><follow-up survey><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><investigate epidemiology><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><member><modifiable risk><nine year old><nine years of age><novel><pathophysiology><pathway><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><study epidemiology><study with follow-up><survey epidemiology><therapeutic target><timeline><treatment strategy><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALAN M JACOBSON

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$780,219

FY 2026

Project Title

Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes- NYU Clinical Center

Grant Number:

5U01DK135012-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/17/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Age><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Brittle Diabetes Mellitus><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Children (0-21)><Collaborations><Community Outreach><Complications of Diabetes Mellitus><Consensus><Continuous Glucose Monitor><Coupled><Data Systems><Deterioration><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiologic Research><Epidemiology><Espanol><Event><Feedback><Follow-Up Studies><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IDDM><IRB><IRBs><IT Systems><Incidence><Information Systems><Information Technology Systems><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intention><Intervention><Intervention Studies><Investigation><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Long Island><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Modeling><NIDDM><Natural History><Neighborhoods><Neurocognitive><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Outcome><Overweight><Pathogenesis><Pathway interactions><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Spanish><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><bilingual><bilingualism><biobank><biorepository><blood glucose regulation><boys><clinical center><cohort><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes control><diabetes mellitus control><diabetes risk><diets><disease onset><disorder onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiologic investigation><epidemiological><experience><follow up><follow-up><follow-up research study><follow-up survey><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><investigate epidemiology><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><member><modifiable risk><nine year old><nine years of age><novel><pathophysiology><pathway><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><study epidemiology><study with follow-up><survey epidemiology><therapeutic target><timeline><treatment strategy><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

LAUREN BERGER SHOMAKER

COLORADO STATE UNIVERSITY, FORT COLLINS, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$763,829

FY 2026

Project Title

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

Grant Number:

5R01DK132557-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract There has been rapid escalation in adolescent-onset type 2 diabetes (T2D), particularly in females from historically disadvantaged racial/ethnic groups. Prevention is critical because adolescent-onset T2D often shows a more aggressive disease course than adult-onset, and eff...

Research Terms

<12-20 years old><21+ years old><Accounting><Active Follow-up><Address><Adherence><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><After Care><After-Treatment><Aftercare><BMI><BMI percentile><BMI z-score><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body mass index><Chronic Disease><Chronic Illness><Cognition Therapy><Cognitive Psychotherapy><Cognitive Therapy><Cognitive treatment><Communities><Conditioning Therapy><Control Groups><Data><Depressed mood><Diabetes prevention><Disadvantaged><Disease><Disorder><Disproportionate number of females><Disproportionate number of women><Disproportionately affects females><Disproportionately affects women><Disproportionately impacts females><Disproportionately impacts women><Disproportionately in females><Disproportionately in women><Effectiveness><Emotional Depression><Ethnic Group><Ethnic Origin><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity><Ethnicity People><Ethnicity Population><Exercise><Fasting><Female><Female Adolescents><Frequencies><Goals><Health><Health Care><Health Instruction><Health Tutoring><Health education><High Risk Woman><Hour><Humulin R><Individual><Insulin><Insulin Resistance><Intervention><Intervention Strategies><Interview><Ketosis-Resistant Diabetes Mellitus><Life Expectancy><Maturity-Onset Diabetes Mellitus><Mediating><Mediator><Mental Depression><Mental Health><Mental Hygiene><Metabolic><Methods><Mission><NIDDK><NIDDM><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Outcome><Pathway interactions><Persons><Phenotype><Physical Fitness><Physical activity><Physiologic><Physiological><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Psychological Health><Public Health><QOL><Quality of life><Quetelet index><Race><Races><Racial Group><Randomized><Randomized, Controlled Trials><Regular Insulin><Research><Risk><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stress><T2 DM><T2D><T2DM><Teen><Teenagers><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Work><Youth><Youth 10-21><active followup><adiposity><adolescence (12-20)><adolescent depression><adolescent girl><adolescents with depression><adult onset diabetes><adulthood><arm><at-risk females><at-risk women><attentional control><behavior intervention><behavioral intervention><cardiorespiratory fitness><cardiorespiratory health><center for epidemiological studies depression scale><child depression><childhood depression><childhood onset depression><chronic disorder><co-morbid><co-morbidity><cognitive behavior intervention><cognitive behavior modification><cognitive behavior therapy><cognitive behavioral intervention><cognitive behavioral modification><cognitive behavioral therapy><cognitive behavioral treatment><combat><comorbidity><comparable efficacy><comparative efficacy><compare efficacy><corpulence><cost><cost effective><cost effective intervention><depressed><depressed adolescents><depression><depression in adolescence><depression symptom><depressive><depressive symptoms><diabetes risk><effective therapy><effective treatment><efficacious intervention><efficacy study><ethnic subgroup><ethnicity group><exercise training><experience><fasted><fasts><female bias><female predominance><female preponderance><females at high risk><fitness><follow up><follow-up><followed up><followup><high risk females><improved><insulin resistant><insulin sensitivity><insulin tolerance><juvenile><juvenile human><ketosis resistant diabetes><lack of physical activity><maturity onset diabetes><pathway><pediatric depression><physical inactivity><post intervention><post treatment><predominance in females><predominance in women><process evaluation><programs><racial><racial background><racial origin><racial population><racial subgroup><randomisation><randomization><randomized control trial><randomly assigned><sadness><sedentary><socio-economic><socio-economically><socioeconomically><socioeconomics><standard of care><teen years><teenage><type 2 DM><type II DM><type two diabetes><women at high risk><women's predominance><women's preponderance><youth age><youth depression><♀>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sarah S Jaser

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$737,312

FY 2026

Project Title

Sleep Promoting Intervention to Improve Diabetes Outcomes and Executive Function in Adolescents with T1D

Grant Number:

5R01DK136695-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/8/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Only 17% of adolescents with type 1 diabetes (T1D) meet the recommended target for hemoglobin A1c, placing them at high risk for acute and long-term complications of T1D. Thus, there is a critical need for novel approaches to improve diabetes management in adolescents with T1D. Insuf...

Research Terms

<0-11 years old><11 year old><11 years of age><21+ years old><Acute><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Blood Glucose><Blood Sugar><Blood Vessels><Brain><Brain Nervous System><Brittle Diabetes Mellitus><CNS lymphatic system><COVID-19><CV-19><Care Givers><Caregivers><Cerebrospinal Fluid><Child><Child Youth><Childhood><Children (0-21)><Circadian Rhythms><Clinical Research><Clinical Study><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Conditioning Therapy><Coronavirus Infectious Disease 2019><DWI (diffusion weighted imaging)><DWI-MRI><Data><Development><Diabetes Mellitus><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Disturbance in cognition><Drainage><Drainage procedure><Dysfunction><Encephalon><Endocrinologist><Equipment and supply inventories><Exhibits><Family><Functional disorder><Glycohemoglobin A><Glycosylated hemoglobin A><Glymphatic impairment><Glymphatic system dysfunction><Glymphatic system impairment><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><History><IDDM><Image><Impaired cognition><Individual><Individual Differences><Insulin-Dependent Diabetes Mellitus><Intercellular Fluid><Interstitial Fluids><Intervention><Inventory><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Leadership><Link><Liquid substance><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Motion><NIDDM><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Neurologist><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Magnetic Resonance Imaging><Nyctohemeral Rhythm><Outcome><Outcome Assessment><Pathway interactions><Physiopathology><Population><Population Heterogeneity><Proteins><Psychologist><Questionnaires><Randomized><Randomized, Controlled Trials><Recommendation><Recording of previous events><Risk><Risk Factors><Sampling><Self Assessment><Self Care><Sleep><Sleep Deprivation><Sleep Disorders><Sleep disturbances><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Sudden-Onset Diabetes Mellitus><Surrogate Markers><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Techniques><Teen><Teenagers><Time><Twenty-Four Hour Rhythm><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Waste Products><Work><Youth><Youth 10-21><Zeugmatography><aberrant sleep><acceptability and feasibility><adult onset diabetes><adulthood><age 11><age 11 years><behavior intervention><behavioral intervention><behavioral sleep health intervention><behavioral sleep health program><behavioral sleep intervention><behavioral sleep strategies><behavioral sleep therapy><behavioral sleep treatment><brain abnormalities><brain health><brain lymph system><brain lymphatic system><care as usual><cerebral spinal fluid><circadian process><circadian rhythmicity><clinical care><cognitive ability><cognitive dysfunction><cognitive function><cognitive loss><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><dMRI><daily biorhythm><deficient sleep><developmental><diabetes><diabetes management><diabetes mellitus management><diabetic management><diffusion tensor imaging><disrupted sleep><disturbed sleep><diverse populations><efficacy testing><eleven year old><eleven years of age><executive control><executive function><experience><fluid><fluid flow><glia lymphatic circuit><glia-lymphatic system><glial lymphatic system><glialymphatic circuit><glialymphatic network><glialymphatic pathway><glialymphatic system><glycemic control><glymphatic circulation><glymphatic clearance><glymphatic clearance pathway><glymphatic dysfunction><glymphatic flow><glymphatic pathway><glymphatic system><glymphatic-lymphatic system><glymphatics><hemoglobin A1c><heterogeneous population><high risk><histories><image-based method><imaging><imaging method><imaging modality><impaired sleep><improved><improvement on sleep><inadequate sleep><insufficient sleep><insulin dependent diabetes><insulin dependent type 1><insulin sensitivity><irregular sleep><juvenile><juvenile diabetes><juvenile diabetes mellitus><juvenile human><ketosis prone diabetes><ketosis resistant diabetes><kids><liquid><malleable risk><maturity onset diabetes><meeting><meetings><modifiable risk><motivational enhancement therapy><motivational interview><multidisciplinary><new approaches><novel><novel approaches><novel strategies><novel strategy><paravascular flow><paravascular system><pathophysiology><pathway><pediatric><personal care><phone session><pilot trial><poor sleep><population diversity><programs><psychoeducation><quality of sleep><randomisation><randomization><randomized control trial><randomized, clinical trials><randomly assigned><recruit><skills><sleep amount><sleep behavior><sleep debt><sleep deficiency><sleep deficit><sleep diseases><sleep disruption><sleep duration><sleep dysfunction><sleep dysregulation><sleep episode><sleep habit><sleep illness><sleep improvement><sleep insufficiency><sleep interval><sleep length><sleep loss><sleep period><sleep problem><sleep quality><sleep quantity><sleep time><sleep/wake behavior><sleep/wake disruption><sleep/wake disturbance><spinal fluid><substantia alba><surrogate bio-markers><surrogate biomarkers><teen years><teenage><telephone based session><telephone session><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><treatment as usual><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><usual care><vascular><wasting><white matter><youngster><youth age>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lori Chaffin Jordan

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$737,312

FY 2026

Project Title

Sleep Promoting Intervention to Improve Diabetes Outcomes and Executive Function in Adolescents with T1D

Grant Number:

5R01DK136695-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/8/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Only 17% of adolescents with type 1 diabetes (T1D) meet the recommended target for hemoglobin A1c, placing them at high risk for acute and long-term complications of T1D. Thus, there is a critical need for novel approaches to improve diabetes management in adolescents with T1D. Insuf...

Research Terms

<0-11 years old><11 year old><11 years of age><21+ years old><Acute><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Blood Glucose><Blood Sugar><Blood Vessels><Brain><Brain Nervous System><Brittle Diabetes Mellitus><CNS lymphatic system><COVID-19><CV-19><Care Givers><Caregivers><Cerebrospinal Fluid><Child><Child Youth><Childhood><Children (0-21)><Circadian Rhythms><Clinical Research><Clinical Study><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Conditioning Therapy><Coronavirus Infectious Disease 2019><DWI (diffusion weighted imaging)><DWI-MRI><Data><Development><Diabetes Mellitus><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Disturbance in cognition><Drainage><Drainage procedure><Dysfunction><Encephalon><Endocrinologist><Equipment and supply inventories><Exhibits><Family><Functional disorder><Glycohemoglobin A><Glycosylated hemoglobin A><Glymphatic impairment><Glymphatic system dysfunction><Glymphatic system impairment><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><History><IDDM><Image><Impaired cognition><Individual><Individual Differences><Insulin-Dependent Diabetes Mellitus><Intercellular Fluid><Interstitial Fluids><Intervention><Inventory><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Leadership><Link><Liquid substance><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Motion><NIDDM><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Neurologist><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Magnetic Resonance Imaging><Nyctohemeral Rhythm><Outcome><Outcome Assessment><Pathway interactions><Physiopathology><Population><Population Heterogeneity><Proteins><Psychologist><Questionnaires><Randomized><Randomized, Controlled Trials><Recommendation><Recording of previous events><Risk><Risk Factors><Sampling><Self Assessment><Self Care><Sleep><Sleep Deprivation><Sleep Disorders><Sleep disturbances><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Sudden-Onset Diabetes Mellitus><Surrogate Markers><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Techniques><Teen><Teenagers><Time><Twenty-Four Hour Rhythm><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Waste Products><Work><Youth><Youth 10-21><Zeugmatography><aberrant sleep><acceptability and feasibility><adult onset diabetes><adulthood><age 11><age 11 years><behavior intervention><behavioral intervention><behavioral sleep health intervention><behavioral sleep health program><behavioral sleep intervention><behavioral sleep strategies><behavioral sleep therapy><behavioral sleep treatment><brain abnormalities><brain health><brain lymph system><brain lymphatic system><care as usual><cerebral spinal fluid><circadian process><circadian rhythmicity><clinical care><cognitive ability><cognitive dysfunction><cognitive function><cognitive loss><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><dMRI><daily biorhythm><deficient sleep><developmental><diabetes><diabetes management><diabetes mellitus management><diabetic management><diffusion tensor imaging><disrupted sleep><disturbed sleep><diverse populations><efficacy testing><eleven year old><eleven years of age><executive control><executive function><experience><fluid><fluid flow><glia lymphatic circuit><glia-lymphatic system><glial lymphatic system><glialymphatic circuit><glialymphatic network><glialymphatic pathway><glialymphatic system><glycemic control><glymphatic circulation><glymphatic clearance><glymphatic clearance pathway><glymphatic dysfunction><glymphatic flow><glymphatic pathway><glymphatic system><glymphatic-lymphatic system><glymphatics><hemoglobin A1c><heterogeneous population><high risk><histories><image-based method><imaging><imaging method><imaging modality><impaired sleep><improved><improvement on sleep><inadequate sleep><insufficient sleep><insulin dependent diabetes><insulin dependent type 1><insulin sensitivity><irregular sleep><juvenile><juvenile diabetes><juvenile diabetes mellitus><juvenile human><ketosis prone diabetes><ketosis resistant diabetes><kids><liquid><malleable risk><maturity onset diabetes><meeting><meetings><modifiable risk><motivational enhancement therapy><motivational interview><multidisciplinary><new approaches><novel><novel approaches><novel strategies><novel strategy><paravascular flow><paravascular system><pathophysiology><pathway><pediatric><personal care><phone session><pilot trial><poor sleep><population diversity><programs><psychoeducation><quality of sleep><randomisation><randomization><randomized control trial><randomized, clinical trials><randomly assigned><recruit><skills><sleep amount><sleep behavior><sleep debt><sleep deficiency><sleep deficit><sleep diseases><sleep disruption><sleep duration><sleep dysfunction><sleep dysregulation><sleep episode><sleep habit><sleep illness><sleep improvement><sleep insufficiency><sleep interval><sleep length><sleep loss><sleep period><sleep problem><sleep quality><sleep quantity><sleep time><sleep/wake behavior><sleep/wake disruption><sleep/wake disturbance><spinal fluid><substantia alba><surrogate bio-markers><surrogate biomarkers><teen years><teenage><telephone based session><telephone session><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><treatment as usual><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><usual care><vascular><wasting><white matter><youngster><youth age>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michael R Rickels

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$731,968

FY 2026

Project Title

Restoring awareness of hypoglycemia in type 1 diabetes

Grant Number:

5U01DK135120-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/25/2022

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY / ABSTRACT This application “Restoring awareness of hypoglycemia in type 1 diabetes” proposes to elucidate the heterogeneity of impaired awareness of hypoglycemia (IAH) in type 1 diabetes through completion of a 24-month Sequential Multiple Assignment Randomized Trial (SMART) designe...

Research Terms

<21+ years old><Achievement><Achievement Attainment><Adrenaline><Adult><Adult Human><Age><Antidiabetic Hormone><Awareness><Blood Glucose><Blood Sugar><Brittle Diabetes Mellitus><Carbohydrates><Clampings><Clinical><Clinical Research><Clinical Study><Clinical Trials Design><Closure by clamp><Continuous Glucose Monitor><Defect><Defense Mechanisms><Development><Diabetes Mellitus><Disease><Disorder><Dose><Drug Therapy><Education><Education for Intervention><Educational Intervention><Educational aspects><Epinephrine><Event><Exposure to><Failure><Generations><Glucagon><Glukagon><HG-Factor><Hepatic><Heterogeneity><Humulin R><Hybrids><Hyperglycemia><Hyperglycemic-Glycogenolytic Factor><Hyperinsulinemia><Hyperinsulinism><Hypoglycemia><IDDM><Impairment><Individual><Ingestion><Instruction Intervention><Insulin><Insulin-Dependent Diabetes Mellitus><Interacinar Cell Pancreatic Polypeptide><Intervention><Islands of Langerhans Transplantation><Islands of Pancreas Transplantation><Islets of Langerhans Grafting><Islets of Langerhans Transplantation><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Life Experience><Measurement><Measures><Morbidity><Novolin R><Outcome><Pancreatic Islets Transplantation><Pancreatic Polypeptide><Participant><Patient Self-Report><Peripheral><Personalized medical approach><Pharmacological Treatment><Pharmacology><Pharmacotherapy><Physiologic><Physiological><Questionnaires><Randomized><Recommendation><Regular Insulin><Reporting><Research Design><Risk><Self-Report><Sequential Multiple Assignment Randomized Trial><Standardization><Study Type><Sudden-Onset Diabetes Mellitus><Symptoms><Syndrome><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Therapeutic><Therapeutic Epinephrine><Time><Training Intervention><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Work><adulthood><ages><autologous islet transplantation><clinical practice><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><counterregulation><developmental><diabetes><disease duration><disease length><drug intervention><drug treatment><experience><falls><glucose RA><glucose disposal><glucose production><glucose rate of appearance><glycemic control><hyperglycemic><hypoglycemic><hypoglycemic episodes><illness length><improved><individualized approach><ingest><instructional intervention><insulin dependent diabetes><insulin dependent type 1><insulin secretion><insulin stimulated glucose disposal><islet auto transplantation><islet beta cell transplantation><islet cell transplant><islet cell transplantation><islet transplantation><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><mortality><novel><permissiveness><personalized approach><personalized health intervention><personalized intervention><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><post-transplant><post-transplantation><posttransplant><posttransplantation><precision approach><precision interventions><psychological defense mechanism><randomisation><randomization><randomized, clinical trials><randomly assigned><response><restoration><standard of care><study design><tailored approach><technology intervention><technology platform><technology system><technology-based interventions><technology-enabled interventions><technology-focused interventions><theories><trial design><type I diabetes><type one diabetes>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stephen CJ Parker

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$723,828

FY 2026

Project Title

Context-specific and combinatorial genetic regulatory grammars in diabetes

Grant Number:

2R01DK117960-06A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2018

End Date:

3/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Over 29 million Americans are diagnosed with diabetes and another 86 million have prediabetes, resulting in an estimated $245 billion in annual medical costs and lost work and wages. Diabetes is a complex disease that results from the combined effects of genetic and environmental fac...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOSE A HALPERIN

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$719,378

FY 2026

Project Title

Urine levels of Glycated CD59 for screening and diagnosis of pregnancy-induced glucose intolerance

Grant Number:

5R01DK136617-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this proposal is to validate glycated CD59 (GCD59) in human urine as a novel diabetes biomarker. This validation will be conducted across several hyperglycemic conditions including pregnancy-induced glucose intolerance/gestational diabetes. The proposal is highly translational and addres...

Research Terms

<0-4 weeks old><ACOG><Address><Adult-Onset Diabetes Mellitus><Affect><American><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><Assay><Belgium><Bioassay><Biocompatible Materials><Biological Assay><Biological Markers><Biomaterials><Blood><Blood Plasma><Blood Reticuloendothelial System><Boston><Cardiovascular Diseases><Classification><Clinical><Clinical Markers><Clinical Treatment Moab><Collection><Complement><Complement Proteins><Complications of Diabetes Mellitus><Consumption><Core Facility><Country><Cross-Product Ratio><D-Glucose><D-Isoglucosamine><Data><Decline in mobility><Decrease in mobility><Decreased mobility><Detection><Development><Devices><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diagnosis><Diagnostic tests><Diminished mobility><ELISA><Early Diagnosis><Early treatment><Eire><Enzyme-Linked Immunosorbent Assay><Equipment><Europe><Fetus><Frequencies><Fructosamine><Future><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Glucose Intolerance><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care Facility><Health Facilities><Hemoglobin A(1)><High Risk Woman><Human><Hyperglycemia><Incidence><Infant><Ireland><Irish Free State><Ketosis-Resistant Diabetes Mellitus><Laboratories><Link><Maturity-Onset Diabetes Mellitus><Measurement><Measures><Methods><Mobility decline><Mobility impairment><Modern Man><Monitor><Monoclonal Antibodies><Morbidity><Mothers><NIDDM><Newborn Infant><Newborns><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><OGTT><Obesity><Odds Ratio><Oral><Oral Glucose Tolerance Test><Outcome><Performance><Plasma><Plasma Serum><Postpartum Period><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy><Pregnancy Outcome><Pregnancy-Induced Diabetes><Pregnant Women><Prenatal care><Prevalence><Publications><Publishing><Reagent><Recommendation><Reduced mobility><Reduction in mobility><Regulatory Protein><Relative Odds><Reproducibility><Research><Research Resources><Resources><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Risk Ratio><Sampling><Scientific Publication><Sensitivity and Specificity><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Systematics><T2 DM><T2D><T2DM><Testing><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><U.S. Preventative Services Task Force><U.S. Preventative Task Force><U.S. Preventive Services Task Force><U.S. Preventive Task Force><US Preventative Services Task Force><US Preventative Task Force><US Preventive Health Services Task Force><US Preventive Services Task Force><US Preventive Task Force><USPSTF><Underserved Population><United States><United States Preventative Services Task Force><United States Preventative Task Force><United States Preventive Services Task Force><United States Preventive Task Force><Urine><Validation><Visit><Woman><access to health care><accessibility of health care><accessibility to health care><adiposity><adult onset diabetes><adverse consequence><adverse outcome><adverse pregnancy outcome><at-risk females><at-risk women><bio-markers><biologic marker><biological material><biomarker><cardiovascular disorder><care facilities><clinical biomarkers><clinical care partner><clinically useful biomarkers><cohort><complement system><complementation><corpulence><cost><cost effective><developmental><diabetes><diagnostic tool><early detection><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><early therapy><enzyme linked immunoassay><expectant mother><expectant women><expecting mother><expecting women><females at high risk><fetal><genetic regulatory protein><glycation><health care access><health care availability><health care service access><health care service availability><healthcare partner><hemoglobin A1c><high risk><high risk females><home test><home-based test><hospital care><hyperglycemic><individuals who are pregnant><ketosis resistant diabetes><mAbs><maternal hyperglycemia><maturity onset diabetes><monoclonal Abs><mortality><new diagnostics><newborn child><newborn children><next generation diagnostics><non-enzymatic glycosylation><nonenzymatic glycosylation><novel><novel diagnostics><people who are pregnant><perinatal outcomes><point of care><post-partum><pre-diabetes><pre-diabetic><prediabetic><pregnancy care><pregnancy diabetes><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal appointment><prenatal checkup><prenatal visit><prospective><public health priorities><recommended screening><regulatory gene product><response><rural area><rural location><rural region><screening><screening guidelines><screening recommendations><screenings><standard of care><those who are pregnant><tool><type 2 DM><type II DM><type two diabetes><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><validations><women at high risk><women who are pregnant>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ambika Pallikunnath Ashraf

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$718,753

FY 2026

Project Title

Predictors of Youth-Onset Type 2 Diabetes: UAB Clinical Center

Grant Number:

5U01DK134966-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><African American><Afro American><Afroamerican><Age><Alabama><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body Composition><Body mass index><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Clinic><Clinical Research><Clinical Study><Collaborations><Consensus><Continuous Glucose Monitor><Coupled><Deterioration><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dysfunction><Early identification><Endocrinology><Enrollment><Epidemiology><Event><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Intra-abdominal><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Latino><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Metabolism and Endocrinology><Modeling><NIDDM><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutritional Science><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Overweight><Participant><Pathogenesis><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Precision Health><Prediabetes><Prediabetes syndrome><Prediabetic State><Prepuberal state><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><T2 DM><T2D><T2DM><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Visit><Youth><Youth 10-21><abdominal adiposity><abdominal fat><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><biobank><biorepository><blood glucose regulation><boys><clinical center><cohort><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disease risk><disorder onset><disorder risk><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><juvenile><juvenile human><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><modifiable risk><nine year old><nine years of age><novel><nutrition science><pathophysiology><pediatric><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><precision nutrition><prediabetic><prepubertal><prepuberty><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><research facility><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><therapeutic target><timeline><treatment strategy><type 2 DM><type II DM><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

BARBARA A GOWER

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$718,753

FY 2026

Project Title

Predictors of Youth-Onset Type 2 Diabetes: UAB Clinical Center

Grant Number:

5U01DK134966-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><African American><Afro American><Afroamerican><Age><Alabama><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body Composition><Body mass index><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Clinic><Clinical Research><Clinical Study><Collaborations><Consensus><Continuous Glucose Monitor><Coupled><Deterioration><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dysfunction><Early identification><Endocrinology><Enrollment><Epidemiology><Event><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Intra-abdominal><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Latino><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Metabolism and Endocrinology><Modeling><NIDDM><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutritional Science><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Overweight><Participant><Pathogenesis><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Precision Health><Prediabetes><Prediabetes syndrome><Prediabetic State><Prepuberal state><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><T2 DM><T2D><T2DM><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Visit><Youth><Youth 10-21><abdominal adiposity><abdominal fat><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><biobank><biorepository><blood glucose regulation><boys><clinical center><cohort><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disease risk><disorder onset><disorder risk><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><juvenile><juvenile human><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><modifiable risk><nine year old><nine years of age><novel><nutrition science><pathophysiology><pediatric><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><precision nutrition><prediabetic><prepubertal><prepuberty><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><research facility><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><therapeutic target><timeline><treatment strategy><type 2 DM><type II DM><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ZHENQI LIU

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$711,928

FY 2026

Project Title

Role of Microvascular insulin resistance and cardiorespiratory fitness in diabetes

Grant Number:

5R01DK124344-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2021

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary The goal of this two-site proposal is to determine whether and by what means insulin resistance, in the form of impaired insulin regulation of microvascular perfusion, leads to decreased functional exercise capacity (FEC) in type 2 diabetes (T2D). Data from our two research teams sug...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Attenuated><Blood Vessels><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Clinical assessments><Colorado><Complications of Diabetes Mellitus><Data><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Differences between sexes><Differs between sexes><Drug Therapy><Dysfunction><Evaluation><Exercise><Functional disorder><Functional impairment><Goals><Health><Heart Vascular><Humulin R><Impairment><Insulin><Insulin Resistance><Intervention><Ketosis-Resistant Diabetes Mellitus><Kinetics><Knowledge><Length of Life><Longevity><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Microvascular Dysfunction><Morbidity><Muscle><Muscle Development><Muscle Mitochondria><Muscle Tissue><Muscle function><Muscular Development><Myocardium><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><O element><O2 element><Outcome><Oxygen><Oxygen Consumption><Performance><Perfusion><Persons><Pharmacological Treatment><Pharmacotherapy><Physical Fitness><Physical activity><Physiologic><Physiological><Physiopathology><Premature Mortality><Publishing><Regular Insulin><Reporting><Research><Research Methodology><Research Methods><Rest><Role><Sarcosomes><Sex Differences><Sexual differences><Site><Skeletal Muscle><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Testing><Therapeutic Effect><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Virginia><Voluntary Muscle><Woman><Work Load><Workload><Youth><Youth 10-21><adult onset diabetes><adulthood><attenuate><attenuates><cardiac function><cardiac muscle><cardiorespiratory fitness><cardiorespiratory health><circulatory system><clinical significance><clinically significant><developmental><diabetes><disparities in sex><drug intervention><drug treatment><exercise capacity><exercise training><experiment><experimental research><experimental study><experiments><function of the heart><functional status><heart function><heart muscle><impaired capacity><improved><in vivo><innovate><innovation><innovative><insight><insulin regulation><insulin resistant><insulin tolerance><ketosis resistant diabetes><life style intervention><lifestyle intervention><maturity onset diabetes><men><microvascular complications><microvascular disease><mortality><muscular><non-diabetic><nondiabetic><novel><pathophysiology><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><remediation><research and methods><response><sex based differences><sex disparity><sex-dependent differences><sex-related differences><sex-specific differences><skeletal><social role><success><survival prediction><therapeutic target><type 2 DM><type II DM><type two diabetes><uptake><vascular><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JUDITH G. REGENSTEINER

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$711,928

FY 2026

Project Title

Role of Microvascular insulin resistance and cardiorespiratory fitness in diabetes

Grant Number:

5R01DK124344-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2021

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary The goal of this two-site proposal is to determine whether and by what means insulin resistance, in the form of impaired insulin regulation of microvascular perfusion, leads to decreased functional exercise capacity (FEC) in type 2 diabetes (T2D). Data from our two research teams sug...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Attenuated><Blood Vessels><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Clinical assessments><Colorado><Complications of Diabetes Mellitus><Data><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Differences between sexes><Differs between sexes><Drug Therapy><Dysfunction><Evaluation><Exercise><Functional disorder><Functional impairment><Goals><Health><Heart Vascular><Humulin R><Impairment><Insulin><Insulin Resistance><Intervention><Ketosis-Resistant Diabetes Mellitus><Kinetics><Knowledge><Length of Life><Longevity><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Microvascular Dysfunction><Morbidity><Muscle><Muscle Development><Muscle Mitochondria><Muscle Tissue><Muscle function><Muscular Development><Myocardium><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><O element><O2 element><Outcome><Oxygen><Oxygen Consumption><Performance><Perfusion><Persons><Pharmacological Treatment><Pharmacotherapy><Physical Fitness><Physical activity><Physiologic><Physiological><Physiopathology><Premature Mortality><Publishing><Regular Insulin><Reporting><Research><Research Methodology><Research Methods><Rest><Role><Sarcosomes><Sex Differences><Sexual differences><Site><Skeletal Muscle><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Testing><Therapeutic Effect><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Virginia><Voluntary Muscle><Woman><Work Load><Workload><Youth><Youth 10-21><adult onset diabetes><adulthood><attenuate><attenuates><cardiac function><cardiac muscle><cardiorespiratory fitness><cardiorespiratory health><circulatory system><clinical significance><clinically significant><developmental><diabetes><disparities in sex><drug intervention><drug treatment><exercise capacity><exercise training><experiment><experimental research><experimental study><experiments><function of the heart><functional status><heart function><heart muscle><impaired capacity><improved><in vivo><innovate><innovation><innovative><insight><insulin regulation><insulin resistant><insulin tolerance><ketosis resistant diabetes><life style intervention><lifestyle intervention><maturity onset diabetes><men><microvascular complications><microvascular disease><mortality><muscular><non-diabetic><nondiabetic><novel><pathophysiology><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><remediation><research and methods><response><sex based differences><sex disparity><sex-dependent differences><sex-related differences><sex-specific differences><skeletal><social role><success><survival prediction><therapeutic target><type 2 DM><type II DM><type two diabetes><uptake><vascular><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JANE E REUSCH

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$711,928

FY 2026

Project Title

Role of Microvascular insulin resistance and cardiorespiratory fitness in diabetes

Grant Number:

5R01DK124344-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2021

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary The goal of this two-site proposal is to determine whether and by what means insulin resistance, in the form of impaired insulin regulation of microvascular perfusion, leads to decreased functional exercise capacity (FEC) in type 2 diabetes (T2D). Data from our two research teams sug...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Attenuated><Blood Vessels><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Clinical assessments><Colorado><Complications of Diabetes Mellitus><Data><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Differences between sexes><Differs between sexes><Drug Therapy><Dysfunction><Evaluation><Exercise><Functional disorder><Functional impairment><Goals><Health><Heart Vascular><Humulin R><Impairment><Insulin><Insulin Resistance><Intervention><Ketosis-Resistant Diabetes Mellitus><Kinetics><Knowledge><Length of Life><Longevity><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Microvascular Dysfunction><Morbidity><Muscle><Muscle Development><Muscle Mitochondria><Muscle Tissue><Muscle function><Muscular Development><Myocardium><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><O element><O2 element><Outcome><Oxygen><Oxygen Consumption><Performance><Perfusion><Persons><Pharmacological Treatment><Pharmacotherapy><Physical Fitness><Physical activity><Physiologic><Physiological><Physiopathology><Premature Mortality><Publishing><Regular Insulin><Reporting><Research><Research Methodology><Research Methods><Rest><Role><Sarcosomes><Sex Differences><Sexual differences><Site><Skeletal Muscle><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Testing><Therapeutic Effect><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Virginia><Voluntary Muscle><Woman><Work Load><Workload><Youth><Youth 10-21><adult onset diabetes><adulthood><attenuate><attenuates><cardiac function><cardiac muscle><cardiorespiratory fitness><cardiorespiratory health><circulatory system><clinical significance><clinically significant><developmental><diabetes><disparities in sex><drug intervention><drug treatment><exercise capacity><exercise training><experiment><experimental research><experimental study><experiments><function of the heart><functional status><heart function><heart muscle><impaired capacity><improved><in vivo><innovate><innovation><innovative><insight><insulin regulation><insulin resistant><insulin tolerance><ketosis resistant diabetes><life style intervention><lifestyle intervention><maturity onset diabetes><men><microvascular complications><microvascular disease><mortality><muscular><non-diabetic><nondiabetic><novel><pathophysiology><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><remediation><research and methods><response><sex based differences><sex disparity><sex-dependent differences><sex-related differences><sex-specific differences><skeletal><social role><success><survival prediction><therapeutic target><type 2 DM><type II DM><type two diabetes><uptake><vascular><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

FIDA BACHA

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$703,094

FY 2026

Project Title

Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes-Texas Children's Center.

Grant Number:

5U01DK134982-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><19 year old><19 years of age><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Age><Ancillary Study><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Black><Black race><Blood Pressure><Body mass index><Cardiovascular Diseases><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Childhood><Childhood diabetes><Children (0-21)><Children's Hospital><Clinical><Collaborations><Communities><Consensus><Continuous Glucose Monitor><County><Coupled><Deterioration><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiology><Event><Family><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Health Insurance><Hemoglobin A(1)><Hispanic><Hormonal><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Medicine><Metabolic><Modeling><Multi-center studies><Multicenter Studies><NIDDM><Neighborhoods><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Overweight><Pathogenesis><Pediatric Hospitals><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><T2 DM><T2D><T2DM><Texas><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Work><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 19><age 19 years><age 9><age 9 years><ages><at risk behavior><biobank><biorepository><blood glucose regulation><boys><cardiovascular disorder><cohort><college><collegiate><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes risk><diets><disease onset><disorder onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><federal poverty level><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><health insurance plan><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><modifiable risk><nine year old><nine years of age><nineteen year old><nineteen years old><novel><pathophysiology><pediatric><pediatric diabetes><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><therapeutic target><timeline><treatment strategy><type 2 DM><type II DM><type two diabetes><work group><working group><youngster><youth age><β-cell><β-cells><βCell>

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Uta Erdbruegger

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$688,673

FY 2026

Project Title

Extracellular Vesicles, Insulin Action and Exercise on Vascular Function in Type 2 Diabetes

Grant Number:

5R01DK133598-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/25/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT ABSTRACT Insulin resistance in the vasculature is often linked to obesity and type 2 diabetes (T2D). This occurs prior to metabolic derangement as evidenced by endothelial dysfunction that, in turn, contributes to the rises in blood pressure and glucose. However, the mechanism by which vascu...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Animal Model><Animal Models and Related Studies><Arteries><Attenuated><BMI><BMI percentile><BMI z-score><Blood><Blood Glucose><Blood Plasma><Blood Platelets><Blood Pressure><Blood Reticuloendothelial System><Blood Sugar><Blood Vessels><Body Tissues><Body fat><Body mass index><Cardiovascular Diseases><Causality><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic Disease><Chronic Illness><Classification><Data><Dependence><Development><Disease Progression><Distant><Dose><Dysfunction><Dyslipidemias><ENOS><Endogenous Nitrate Vasodilator><Endothelial Cells><Endothelial Nitric Oxide Synthase><Endothelium><Endothelium-Derived Nitric Oxide><Etiology><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Exercise><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Fostering><Foundations><Functional disorder><Future><Glucose Clamp><Health><Human><Humulin R><Hyperglycemia><Hyperinsulinemic Clamp><Hypertension><Image><Immunoblotting><Impairment><In Vitro><In vivo analysis><Infusion><Infusion procedures><Insulin><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin Resistance><Insulin-Dependent Tyrosine Protein Kinase><Intervention><Intracellular Communication and Signaling><Ischemia><Ketosis-Resistant Diabetes Mellitus><L-NAME><Leanness><Link><Marrow platelet><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Metabolic><Metabolic syndrome><Mice><Mice Mammals><MicroRNAs><Microcirculation><Modeling><Modern Man><Mononitrogen Monoxide><Morbidity><Murine><Mus><Myography><N omega-Nitro-L-arginine Methyl Ester><N(G)-Nitro-L-arginine Methyl Ester><N(G)-Nitroarginine Methyl Ester><NG-Nitro-L-Arginine Methyl Ester><NG-Nitroarginine Methyl Ester><NIDDM><NOS3><NOS3 gene><Nitric Oxide><Nitric Oxide Synthase 3><Nitrogen Monoxide><Nitrogen Protoxide><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Polyadenylated RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Participant><Pathologic><Patients><Persons><Phenotype><Physiologic pulse><Physiology><Physiopathology><Plasma><Plasma Serum><Platelets><Prevention><Proteins><Pulse><Quetelet index><RNA><RNA Gene Products><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Resistance><Reticuloendothelial System, Serum, Plasma><Ribonucleic Acid><Risk Reduction><Rodent><Rodentia><Rodents Mammals><Role><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Factor Proto-Oncogene><Signaling Molecule><Signaling Pathway Gene><Signaling Protein><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><System><Systematics><T2 DM><T2D><T2DM><Testing><Thinness><Thrombocytes><Time><Tissues><Training><Translating><Trees><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Type III nitric oxide synthase><United States><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vasodilatation><Vasodilation><Vasorelaxation><Western Blotting><Western Immunoblotting><Work><adiposity><adult onset diabetes><adulthood><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><attenuate><attenuates><biological signal transduction><blood vessel disorder><cardiometabolic><cardiometabolism><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><causation><chronic disorder><clinical relevance><clinically relevant><compare to control><comparison control><contrast enhanced><corpulence><customized therapy><customized treatment><developmental><disease causation><dosage><endothelial cell derived relaxing factor><endothelial dysfunction><exercise training><extracellular vesicles><flow cytophotometry><glucose tolerance><glucose uptake><high blood pressure><hyperglycemic><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><improved><in vivo><in vivo Model><in vivo evaluation><in vivo testing><indexing><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><infusions><inhibitor><insight><insulin resistant><insulin sensitivity><insulin signaling><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><miRNA><model of animal><mortality><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><obesity development><pathophysiology><patient specific therapies><patient specific treatment><pharmacologic><precision medicine><precision-based medicine><pressure><prevent><preventing><prospective><protein blotting><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><resistant><response><risk-reducing><social role><tailored medical treatment><tailored therapy><tailored treatment><tool><transcriptome sequencing><transcriptomic sequencing><type 2 DM><type II DM><type two diabetes><ultrasound><unique treatment><uptake><vascular><vascular dysfunction><vasculopathy><vesicle release><vesicular release><wortmannin>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Steven K Malin

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$688,673

FY 2026

Project Title

Extracellular Vesicles, Insulin Action and Exercise on Vascular Function in Type 2 Diabetes

Grant Number:

5R01DK133598-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/25/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT ABSTRACT Insulin resistance in the vasculature is often linked to obesity and type 2 diabetes (T2D). This occurs prior to metabolic derangement as evidenced by endothelial dysfunction that, in turn, contributes to the rises in blood pressure and glucose. However, the mechanism by which vascu...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Animal Model><Animal Models and Related Studies><Arteries><Attenuated><BMI><BMI percentile><BMI z-score><Blood><Blood Glucose><Blood Plasma><Blood Platelets><Blood Pressure><Blood Reticuloendothelial System><Blood Sugar><Blood Vessels><Body Tissues><Body fat><Body mass index><Cardiovascular Diseases><Causality><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Chronic Disease><Chronic Illness><Classification><Data><Dependence><Development><Disease Progression><Distant><Dose><Dysfunction><Dyslipidemias><ENOS><Endogenous Nitrate Vasodilator><Endothelial Cells><Endothelial Nitric Oxide Synthase><Endothelium><Endothelium-Derived Nitric Oxide><Etiology><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Exercise><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Fostering><Foundations><Functional disorder><Future><Glucose Clamp><Health><Human><Humulin R><Hyperglycemia><Hyperinsulinemic Clamp><Hypertension><Image><Immunoblotting><Impairment><In Vitro><In vivo analysis><Infusion><Infusion procedures><Insulin><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin Resistance><Insulin-Dependent Tyrosine Protein Kinase><Intervention><Intracellular Communication and Signaling><Ischemia><Ketosis-Resistant Diabetes Mellitus><L-NAME><Leanness><Link><Marrow platelet><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Metabolic><Metabolic syndrome><Mice><Mice Mammals><MicroRNAs><Microcirculation><Modeling><Modern Man><Mononitrogen Monoxide><Morbidity><Murine><Mus><Myography><N omega-Nitro-L-arginine Methyl Ester><N(G)-Nitro-L-arginine Methyl Ester><N(G)-Nitroarginine Methyl Ester><NG-Nitro-L-Arginine Methyl Ester><NG-Nitroarginine Methyl Ester><NIDDM><NOS3><NOS3 gene><Nitric Oxide><Nitric Oxide Synthase 3><Nitrogen Monoxide><Nitrogen Protoxide><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Polyadenylated RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Participant><Pathologic><Patients><Persons><Phenotype><Physiologic pulse><Physiology><Physiopathology><Plasma><Plasma Serum><Platelets><Prevention><Proteins><Pulse><Quetelet index><RNA><RNA Gene Products><RNA Seq><RNA sequencing><RNAseq><Regular Insulin><Resistance><Reticuloendothelial System, Serum, Plasma><Ribonucleic Acid><Risk Reduction><Rodent><Rodentia><Rodents Mammals><Role><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Factor Proto-Oncogene><Signaling Molecule><Signaling Pathway Gene><Signaling Protein><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><System><Systematics><T2 DM><T2D><T2DM><Testing><Thinness><Thrombocytes><Time><Tissues><Training><Translating><Trees><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Type III nitric oxide synthase><United States><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vasodilatation><Vasodilation><Vasorelaxation><Western Blotting><Western Immunoblotting><Work><adiposity><adult onset diabetes><adulthood><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><attenuate><attenuates><biological signal transduction><blood vessel disorder><cardiometabolic><cardiometabolism><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><causation><chronic disorder><clinical relevance><clinically relevant><compare to control><comparison control><contrast enhanced><corpulence><customized therapy><customized treatment><developmental><disease causation><dosage><endothelial cell derived relaxing factor><endothelial dysfunction><exercise training><extracellular vesicles><flow cytophotometry><glucose tolerance><glucose uptake><high blood pressure><hyperglycemic><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><improved><in vivo><in vivo Model><in vivo evaluation><in vivo testing><indexing><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><infusions><inhibitor><insight><insulin resistant><insulin sensitivity><insulin signaling><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><miRNA><model of animal><mortality><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><obesity development><pathophysiology><patient specific therapies><patient specific treatment><pharmacologic><precision medicine><precision-based medicine><pressure><prevent><preventing><prospective><protein blotting><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><resistant><response><risk-reducing><social role><tailored medical treatment><tailored therapy><tailored treatment><tool><transcriptome sequencing><transcriptomic sequencing><type 2 DM><type II DM><type two diabetes><ultrasound><unique treatment><uptake><vascular><vascular dysfunction><vasculopathy><vesicle release><vesicular release><wortmannin>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Vernon M Chinchilli

PENNSYLVANIA STATE UNIV HERSHEY MED CTR, HERSHEY, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$674,478

FY 2026

Project Title

Diabetes RElated to Acute Pancreatitis and its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics (DREAM-ON)

Grant Number:

5R01DK138060-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT / PROJECT SUMMARY Background: Acute pancreatitis (AP) is a common and serious condition, accounting for more than 300,000 hospitalizations and over $2 billion in health care costs per year in the United States alone. Patients with AP have an increased risk of several complications including...

Research Terms

<21+ years old><Accounting><Active Follow-up><Address><Adult><Adult Human><Ancillary Study><Beta Cell><Brittle Diabetes Mellitus><Causality><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Classification><Clinical><Complement><Complement Proteins><Continuous Glucose Monitor><D-Glucose><Data><Development><Dextrose><Diabetes Mellitus><Diagnosis><Dysfunction><Enrollment><Etiology><Exocrine pancreatic insufficiency><Functional disorder><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Susceptibility><Genetic propensity><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care Costs><Health Costs><Hemoglobin A(1)><Hospital Admission><Hospitalization><Humulin R><IDDM><IVGTT><Immune><Immunes><Incidence><Individual><Inherited Predisposition><Inherited Susceptibility><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin deficiency><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Measures><Meta-Analysis><Metabolic><Mild obesity><Modeling><Morbidity><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Necrosis><Necrotic><Novolin R><OGTT><Observational Study><Oral Glucose Tolerance Test><Outcome><Pancreas><Pancreatic><Pancreatic Insufficiency><Pancreatitis><Participant><Pathogenesis><Patient Care><Patient Care Delivery><Patients><Physiopathology><Pilot Projects><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predicting Risk><Predictive Factor><Prospective, cohort study><Recommendation><Regular Insulin><Reporting><Research><Risk><Sampling><Schedule><Severities><Standardization><Subcellular Process><Sudden-Onset Diabetes Mellitus><Systematics><T1 DM><T1 diabetes><T1D><T1DM><Testing><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Uncertainty><United States><United States National Institutes of Health><Visit><active followup><acute pancreatitis><adulthood><age associated><age correlated><age dependent><age linked><age related><age specific><autoimmune beta cell destruction><autoimmune islet destruction><beta cell autoimmunity><care for patients><care of patients><caring for patients><causation><chronic pancreatitis><clinical research site><clinical risk><clinical site><complementation><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><design><designing><developmental><diabetes><diabetes risk><disease causation><doubt><enroll><experience><fasting plasma glucose><follow up><follow-up><followed up><followup><forecasting risk><genetic vulnerability><genetically predisposed><glycemic control><hemoglobin A1c><high risk><indexing><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><intravenous glucose tolerance><intravenous glucose tolerance test><islet autoantibody><islet autoimmunity><islet cell antibody><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><mortality><novel><observational cohort study><observational research study><observational survey><pancreas imaging><participant enrollment><pathophysiology><patient enrollment><pilot study><pre-diabetes><pre-diabetic><prediabetic><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><prospective><recurrent pancreatitis><risk prediction><risk predictions><routine care><screening><screenings><type I diabetes><type one diabetes><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RICHARD E PRATLEY

PENNSYLVANIA STATE UNIV HERSHEY MED CTR, HERSHEY, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$674,478

FY 2026

Project Title

Diabetes RElated to Acute Pancreatitis and its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics (DREAM-ON)

Grant Number:

5R01DK138060-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

ABSTRACT / PROJECT SUMMARY Background: Acute pancreatitis (AP) is a common and serious condition, accounting for more than 300,000 hospitalizations and over $2 billion in health care costs per year in the United States alone. Patients with AP have an increased risk of several complications including...

Research Terms

<21+ years old><Accounting><Active Follow-up><Address><Adult><Adult Human><Ancillary Study><Beta Cell><Brittle Diabetes Mellitus><Causality><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Classification><Clinical><Complement><Complement Proteins><Continuous Glucose Monitor><D-Glucose><Data><Development><Dextrose><Diabetes Mellitus><Diagnosis><Dysfunction><Enrollment><Etiology><Exocrine pancreatic insufficiency><Functional disorder><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Susceptibility><Genetic propensity><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care Costs><Health Costs><Hemoglobin A(1)><Hospital Admission><Hospitalization><Humulin R><IDDM><IVGTT><Immune><Immunes><Incidence><Individual><Inherited Predisposition><Inherited Susceptibility><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin deficiency><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Measures><Meta-Analysis><Metabolic><Mild obesity><Modeling><Morbidity><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Necrosis><Necrotic><Novolin R><OGTT><Observational Study><Oral Glucose Tolerance Test><Outcome><Pancreas><Pancreatic><Pancreatic Insufficiency><Pancreatitis><Participant><Pathogenesis><Patient Care><Patient Care Delivery><Patients><Physiopathology><Pilot Projects><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predicting Risk><Predictive Factor><Prospective, cohort study><Recommendation><Regular Insulin><Reporting><Research><Risk><Sampling><Schedule><Severities><Standardization><Subcellular Process><Sudden-Onset Diabetes Mellitus><Systematics><T1 DM><T1 diabetes><T1D><T1DM><Testing><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Uncertainty><United States><United States National Institutes of Health><Visit><active followup><acute pancreatitis><adulthood><age associated><age correlated><age dependent><age linked><age related><age specific><autoimmune beta cell destruction><autoimmune islet destruction><beta cell autoimmunity><care for patients><care of patients><caring for patients><causation><chronic pancreatitis><clinical research site><clinical risk><clinical site><complementation><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><design><designing><developmental><diabetes><diabetes risk><disease causation><doubt><enroll><experience><fasting plasma glucose><follow up><follow-up><followed up><followup><forecasting risk><genetic vulnerability><genetically predisposed><glycemic control><hemoglobin A1c><high risk><indexing><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><intravenous glucose tolerance><intravenous glucose tolerance test><islet autoantibody><islet autoimmunity><islet cell antibody><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><mortality><novel><observational cohort study><observational research study><observational survey><pancreas imaging><participant enrollment><pathophysiology><patient enrollment><pilot study><pre-diabetes><pre-diabetic><prediabetic><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><prospective><recurrent pancreatitis><risk prediction><risk predictions><routine care><screening><screenings><type I diabetes><type one diabetes><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michelle E Kimple

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$648,973

FY 2026

Project Title

The role of G protein-dependent and -independent EP3 signaling in beta-cell compensation and diabetes

Grant Number:

5R01DK137505-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/18/2024

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY/ABSTRACT: Diabetes is a costly and complex chronic illness and a serious public health problem. The number of individuals with diabetes, particularly obesity-linked type 2 diabetes (T2D), is certain to increase over the next decades. Shockingly, the children of today have an estimated overal...

Research Terms

<0-11 years old><3'5'-cyclic ester of AMP><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Adult-Onset Diabetes Mellitus><Agonist><Arachidonic Acids><Area><Assay><Beta Cell><Binding><Bioassay><Biochemical><Biological Assay><Blood Circulation><Blood Glucose><Blood Sugar><Bloodstream><Body Tissues><Caring><Cell Body><Cell Communication and Signaling><Cell Function><Cell Growth in Number><Cell Multiplication><Cell Physiology><Cell Process><Cell Proliferation><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular Proliferation><Cellular biology><Child><Child Youth><Children (0-21)><Chronic><Chronic Disease><Chronic Illness><Clinical><Compensation><Complex><Confocal Microscopy><Critical Paths><Critical Pathways><Cyclic AMP><D-Glucose><Data><Dextrose><Diabetes Mellitus><Diabetes prevention><Diabetic mouse><Dinoprostone><Drugs><Dysfunction><Endocrine Gland Secretion><Enzyme Gene><Enzymes><Failure><Foundations><Functional disorder><Future><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G-Protein alpha Subunit><G-Protein α Subunit><G-Protein-Coupled Receptors><G-Proteins><GDP Dissociation Factor><GDP Dissociation Stimulators><GDP Exchange Factors><GDP-GTP Exchange Protein><GDP-GTP Reversing Factors><GLP-1><GLP-1 receptor><GLP-I receptor><GPCR><GTP GDP exchange factor><GTP-Binding Protein alpha Subunits><GTP-Binding Protein α Subunits><GTP-Binding Proteins><GTP-Regulatory Proteins><Glp-1><Glucose><Goals><Guanine Nucleotide Coupling Protein><Guanine Nucleotide Exchange Factors><Guanine Nucleotide Exchange Protein><Guanine Nucleotide Regulatory Proteins><Guanine Nucleotide Releasing Factors><Guanyl-Nucleotide Exchange Factor><Guanyl-Nucleotide Releasing Factor><Health><Hormones><Human><Humulin R><Image><Individual><Insulin><Insulin Cell><Insulin Secreting Cell><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Leanness><Link><Maturity-Onset Diabetes Mellitus><Measurement><Medication><Membrane><Metabolic><Methods><Mice><Mice Mammals><Microscopy><Modern Man><Molecular><Molecular Interaction><Monomeric G-Proteins><Monomeric GTP-Binding Proteins><Murine><Mus><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obese Mice><Obesity><Organ Donor><PGE2><PGE2 alpha><PGE2alpha><Pancreas><Pancreatic><Pancreatic beta Cell><Pancreatic β-Cell><Pathway interactions><Patients><Pharmaceutical Preparations><Phosphorylation><Physiopathology><Play><Preventive><Production><Proliferating><Prostaglandin E2><Prostaglandin E2 alpha><Prostaglandin E2alpha><Prostaglandins><Prostanoids><Protein Phosphorylation><Proteomics><Public Health><Publishing><Qualifying><Receptor Protein><Regular Insulin><Research><Rodent><Rodentia><Rodents Mammals><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure of beta Cell of islet><Subcellular Process><T2 DM><T2D><T2DM><Techniques><Testing><Therapeutic><Therapeutic Hormone><Thinness><Time><Tissues><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Variant><Variation><Visualization><Work><adenosine 3'5' monophosphate><adiposity><adult onset diabetes><biological signal transduction><cAMP><cell biology><cell imaging><cellular imaging><cellular targeting><chronic disorder><corpulence><cost><diabetes><diabetes mellitus therapy><diabetes mouse model><diabetes therapy><drug/agent><exchange factor><functional loss><glucagon-like peptide 1><glucagon-like peptide-1 receptor><healthspan><healthy life span><imaging><improved><innovate><innovation><innovative><insulin secretion><islet><ketosis resistant diabetes><kids><life-time risk><lifetime risk><maturity onset diabetes><membrane structure><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mutant><new approaches><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><non-diabetic><nondiabetic><novel approaches><novel drug target><novel druggable target><novel pharmacotherapy target><novel strategies><novel strategy><novel therapeutic target><novel therapy target><ob/ob mouse><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><pathway><preservation><prevent><preventing><programs><receptor><response><sensor><social role><type 2 DM><type II DM><type two diabetes><youngster><β-cell><β-cells><βCell>

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Samuel Klein

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$627,620

FY 2026

Project Title

EFFICACY AND SAFETY OF A KETOGENIC DIET IN TYPE 1 DIABETES

Grant Number:

5R01DK137837-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Type 1 diabetes (T1D) is caused by autoimmune destruction of β-cells that causes dependence on exogenous insulin. Despite remarkable advances in diabetes device technology, less than 25% of adults with T1D achieve the recommended HbA1c target of <7.0%. Moreover, subcutaneous deliver...

Research Terms

<(TNF)-α><0-11 years old><21+ years old><Acute><Address><Adherence><Adipose tissue><Adult><Adult Human><Affect><American><Antidiabetic Hormone><Apo-B><ApoB><Apolipoproteins B><Artificial Pancreas><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Behavioral><Biochemistry><Biological Chemistry><Blood Glucose><Blood Plasma><Blood Serum><Blood Sugar><Body Composition><Body Weight><Bone 4-Carboxyglutamic Protein><Bone Density><Bone Gla Protein><Bone Mineral Density><Bone gamma-Carboxyglutamic Acid Protein><Brittle Diabetes Mellitus><C-terminal type I collagen telopeptide><CO2><CTX><CYCLO-cell><Cachectin><Calcium><Carbohydrates><Carbon Dioxide><Carbonic Anhydride><Carloxan><Case Series><Cause of Death><Child><Child Youth><Children (0-21)><Cholesterol><Chronic><Ciclofosfamida><Ciclofosfamide><Cicloxal><Clafen><Claphene><Complications of Diabetes Mellitus><Consumption><Coxa><Creatinine><Cycloblastin><Cycloblastine><Cyclophospham><Cyclophosphamide><Cyclophosphamidum><Cyclophosphan><Cyclophosphane><Cyclophosphanum><Cyclostin><Cyclostine><Cytophosphan><Cytophosphane><Cytoxan><D-Glucose><DEXA><DXA><Dependence><Development><Devices><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Acidosis><Diabetic Complications><Diabetic Ketoacidosis><Diabetic Ketosis><Diet therapy><Dietary Carbohydrates><Dietitian><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dyslipidemias><Eating Behavior><Education><Educational aspects><Electrolytes><Endoxan><Endoxana><Enduxan><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Event><Evidence based practice guidelines><Fats><Fatty Tissue><Fatty acid glycerol esters><Femur><Food><Fosfaseron><Genoxal><Genuxal><Glomerular Filtration Rate><Glucagon><Glucose><Glucose Clamp><Glukagon><Glycohemoglobin A><Glycosylated hemoglobin A><HDL><HDL Lipoproteins><HG-Factor><HPGF><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Heavy Lipoproteins><Hemoglobin A(1)><Hepatic><Hepatocyte-Stimulating Factor><High Density Lipoproteins><Hip><Hip region structure><Hour><Humulin R><Hybridoma Growth Factor><Hybrids><Hyperglycemia><Hyperglycemic-Glycogenolytic Factor><Hyperinsulinemia><Hyperinsulinemic Clamp><Hyperinsulinism><Hypoglycemia><IDDM><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Iatrogenesis><Impairment><Incidence><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Intake><Interleukin-6><Interview><Intra-abdominal><Isocaloric><Juvenile-Onset Diabetes Mellitus><Ketone Bodies><Ketones><Ketosis><Ketosis-Prone Diabetes Mellitus><Knowledge><LDL><LDL Lipoproteins><Leanness><Ledoxina><Life Expectancy><Life Style><Lifestyle><Lipids><Lipoproteins><Liver><Low-Density Lipoproteins><MGI-2><Macrophage-Derived TNF><Measures><Metabolic><Methods><Mitoxan><Monitor><Monocyte-Derived TNF><Myeloid Differentiation-Inducing Protein><N-terminal><NH2-terminal><Neck><Neosar><Novolin R><Nutrition><Observational Study><Osteocalcin><PAI-1><PAI1><PLANH1><Patients><Peripheral><Persons><Plasma><Plasma Serum><Plasmacytoma Growth Factor><Plasminogen Activator Inhibitor 1><Preparation><Prevalence><Procedures><Procollagen><Procytox><QOL><Quality of life><Questionnaires><Randomized, Controlled Trials><Recommendation><Records><Regular Insulin><Renal function><Research Institute><Reticuloendothelial System, Serum, Plasma><Risk><Risk Reduction><Safety><Sendoxan><Serine or Cysteine Proteinase Inhibitor Clade E Member 1><Serum><Site><Social Behavior><Spinal Column><Spine><Sudden-Onset Diabetes Mellitus><Survey Instrument><Surveys><Syklofosfamid><System><T1 DM><T1 diabetes><T1D><T1DM><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Technology><Testing><Thinness><Time><Triacylglycerol><Triglycerides><Trioxopurine><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Type 1 Diabetes Mellitus><Type 1 Plasminogen Activator Inhibitor><Type 1 diabetes><Type I Diabetes Mellitus><United States><Universities><Uric Acid><Urine><Vertebral column><Vitamin K-Dependent Bone Protein><Vitamin K-Dependent Calcium-Binding Protein><Washington><Zytoxan><adipogenesis><adipose><adulthood><alpha-Lipoproteins><autoimmune beta cell destruction><autoimmune islet destruction><backbone><beta cell autoimmunity><beta-Lipoproteins><bone health><bone turnover><cardiometabolic><cardiometabolic risk><cardiometabolism><cardiovascular risk><cardiovascular risk factor><clinical efficacy><cost><cystatin C><determine efficacy><developmental><diabetes><diabetes distress><diabetes-related distress><diabetes-specific distress><diabetic ketoacidotic><diet adherence><diet control><dietary adherence><dietary control><dietary therapy><distress related to diabetes><distress specific to diabetes><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><evidence based guidelines><evidence based recommendations><examine efficacy><food craving><glycemic control><hemoglobin A1c><hepatic body system><hepatic organ system><hyperglycemic><hypoglycemic><hypoglycemic episodes><iatrogenic><iatrogenically><iatrogenicity><implementation outcomes><improved><improved outcome><inflammation marker><inflammatory marker><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin sensitivity><insulin tolerance><interest><interferon beta 2><intrahepatic><islet autoimmunity><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><keto diet><ketogenic diet><ketosis prone diabetes><kidney function><kids><life span><lifespan><lipid biosynthesis><lipogenesis><medical attention><medical college><medical schools><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><observational research study><observational survey><particle><post gamma-globulins><post-gamma-protein><preparations><primary outcome><randomized control trial><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><safety assessment><school of medicine><social><social determinants><socio-demographic factors><sociobehavior><sociobehavioral><sociodemographic factors><sociodeterminant><subcutaneous><subdermal><type I diabetes><type one diabetes><white adipose tissue><yellow adipose tissue><youngster>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MEGAN MORIARTY KELSEY

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$621,623

FY 2026

Project Title

What Activates Type 2 diabetes in Children (WATCH)

Grant Number:

5U01DK134958-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><21+ years old><9 year old><9 years of age><Access to Care><Active Follow-up><Acute><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aeroseb-HC><Affect><Age><Amputation><Anxiety><Apoplexy><Application Context><Approaches to prevention><Attention><BMI><BMI percentile><BMI z-score><Behavior><Behavior monitoring><Behavioral><Beta Cell><Biochemical><Bioelectrical Impedance><Biolectric Impedance><Biological><Biometrics><Biometry><Biostatistics><Blood Banks><Blood Pressure><Body Composition><Body mass index><Brain Vascular Accident><COVID-19><CV-19><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Catchment Area><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Center for Translational Science Activities><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cetacort><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Children's Hospital><Chronic><Circadian Rhythms><Clinic><Clinical><Code><Coding System><Cognitive Discrimination><Collaborations><Colorado><Communities><Complications of Diabetes Mellitus><Consensus><Continuous Glucose Monitor><Coronavirus Infectious Disease 2019><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Coupled><Creativeness><DEXA><DXA><Dermacort><Deterioration><Development><Diabetes Complications><Diabetes Mellitus><Diabetes prevention><Diabetes-Related Complications><Diabetic Complications><Diagnostic><Diet><Dimethylbiguanidine><Dimethylguanylguanidine><Discrimination><Disease><Disorder><Drugs><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Early identification><Ecological momentary assessment><Economic Income><Economical Income><Education><Educational aspects><Eldecort><Endocrine Gland Secretion><Enrollment><Epidemiology><Ethnic Origin><Ethnicity><Event><Exposure to><Failure><Family><Family Medical History><Family Medical History Epidemiology><Family history of><Feces><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic><Genetic Materials><Geography><Gestational Diabetes><Gestational Diabetes Mellitus><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hair><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Health Care Costs><Health Costs><Health Services Accessibility><Heart Vascular><Hemoglobin A(1)><Hispanic><History><Hormones><Humulin R><Hydrocortisone><Hydrocortone><Hytone><IRB><IRBs><Impoverished><In Situ><Income><Infrastructure><Institutional Review Boards><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Interview><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Latino><Lead><Leadership><Life Style><Lifestyle><Lipids><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Medical><Medical History><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Mental Depression><Metabolic><Metformin><Modeling><Monitor><Morbidity><Myocardial Infarct><Myocardial Infarction><N,N-dimethyl-imidodicarbonimidic diamide><NIDDK><NIDDM><NIH><NMR Imaging><NMR Tomography><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Neighborhoods><Newly Diagnosed><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nuclear Magnetic Resonance Imaging><Nutracort><Nyctohemeral Rhythm><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral><Oral Glucose Tolerance Test><Outcome><Overweight><Participant><Pattern><Pb element><Pediatric Hospitals><Perception><Personal Medical History><Personal Medical History Epidemiology><Pharmaceutical Preparations><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Pilot Projects><Play><Polysomnography><Population><Position><Positioning Attribute><Poverty><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy-Induced Diabetes><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Proctocort><Productivity><Protocol><Protocols documentation><Provider><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Race><Races><Recording of previous events><Regular Insulin><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Rural Community><Sampling><Schedule><Sedentary behavior><Sedentary life-style><Site><Sleep><Sleep Monitoring><Sleep disturbances><Slow-Onset Diabetes Mellitus><Social status><Somnography><Stable Diabetes Mellitus><Standardization><Stress><Stroke><Subcellular Process><T2 DM><T2D><T2DM><Therapeutic Hormone><Time><Translational Research><Translational Science><Twenty-Four Hour Rhythm><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Universities><Urban Community><Urban Population><Urine><Visit><Weight Gain><Weight Increase><Youth><Youth 10-21><Zeugmatography><aberrant sleep><access to health services><access to services><access to treatment><accessibility to health services><active followup><adiposity><adult onset diabetes><adulthood><adverse childhood events><adverse childhood experiences><age 9><age 9 years><ages><at risk behavior><availability of services><behavioral monitoring><biobank><biologic><biorepository><blood glucose regulation><body weight gain><body weight increase><boys><brain attack><bully><bullying><cardiac infarct><cardiometabolic><cardiometabolism><care access><cerebral vascular accident><cerebrovascular accident><circadian process><circadian rhythmicity><circulatory system><clinical translation><clinically translatable><co-morbid><co-morbidity><cohort><comorbidity><computer based prediction><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><coronary attack><coronary infarct><coronary infarction><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><corpulence><creativity><critical period><daily biorhythm><demographics><depression><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><disrupted sleep><disturbed sleep><drug/agent><early onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><glycemic control><health equity promotion><health service access><health services availability><heart attack><heart infarct><heart infarction><heavy metal Pb><heavy metal lead><hemoglobin A1c><high risk><histories><impaired glucose tolerance><impaired sleep><improved><incomes><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><irregular sleep><juvenile><juvenile human><ketosis resistant diabetes><kids><machine based learning><malleable risk><maturity onset diabetes><member><modifiable risk><nine year old><nine years of age><novel><obesity intervention><obesity therapy><obesity treatment><optimal therapies><optimal treatments><pandemic><pandemic disease><pathophysiology><patient population><pediatric><phase 2 study><phase II study><phenotypic data><pilot study><pre-diabetes><pre-diabetic><prediabetic><predictive modeling><pregnancy diabetes><preservation><prevent><preventing><primary care practice><primary end point><primary endpoint><programs><progression risk><promote health equity><psychologic><psychological><psychosocial><racial><racial background><racial minority><racial origin><racism><recruit><response><response to therapy><response to treatment><rural patients><safety net><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><service availability><sleep disruption><sleep dysregulation><sleep measurement><sleep polysomnography><sleep/wake disruption><sleep/wake disturbance><social><social position><social role><social standing><stool><stroked><strokes><success><therapeutic response><therapeutic target><therapy response><timeline><translation research><translational investigation><translational research center><translational sciences center><treatment access><treatment program><treatment response><treatment responsiveness><treatment strategy><type 2 DM><type 2 diabetes in children><type II DM><type two diabetes><urban group><urban individual><urban people><wt gain><youngster><youth age><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KRISTEN Jane NADEAU

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$621,623

FY 2026

Project Title

What Activates Type 2 diabetes in Children (WATCH)

Grant Number:

5U01DK134958-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resistance, enhanc...

Research Terms

<0-11 years old><21+ years old><9 year old><9 years of age><Access to Care><Active Follow-up><Acute><Address><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aeroseb-HC><Affect><Age><Amputation><Anxiety><Apoplexy><Application Context><Approaches to prevention><Attention><BMI><BMI percentile><BMI z-score><Behavior><Behavior monitoring><Behavioral><Beta Cell><Biochemical><Bioelectrical Impedance><Biolectric Impedance><Biological><Biometrics><Biometry><Biostatistics><Blood Banks><Blood Pressure><Body Composition><Body mass index><Brain Vascular Accident><COVID-19><CV-19><Cardiac infarction><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Catchment Area><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Center for Translational Science Activities><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cetacort><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Children's Hospital><Chronic><Circadian Rhythms><Clinic><Clinical><Code><Coding System><Cognitive Discrimination><Collaborations><Colorado><Communities><Complications of Diabetes Mellitus><Consensus><Continuous Glucose Monitor><Coronavirus Infectious Disease 2019><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Coupled><Creativeness><DEXA><DXA><Dermacort><Deterioration><Development><Diabetes Complications><Diabetes Mellitus><Diabetes prevention><Diabetes-Related Complications><Diabetic Complications><Diagnostic><Diet><Dimethylbiguanidine><Dimethylguanylguanidine><Discrimination><Disease><Disorder><Drugs><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Early identification><Ecological momentary assessment><Economic Income><Economical Income><Education><Educational aspects><Eldecort><Endocrine Gland Secretion><Enrollment><Epidemiology><Ethnic Origin><Ethnicity><Event><Exposure to><Failure><Family><Family Medical History><Family Medical History Epidemiology><Family history of><Feces><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic><Genetic Materials><Geography><Gestational Diabetes><Gestational Diabetes Mellitus><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hair><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Health Care Costs><Health Costs><Health Services Accessibility><Heart Vascular><Hemoglobin A(1)><Hispanic><History><Hormones><Humulin R><Hydrocortisone><Hydrocortone><Hytone><IRB><IRBs><Impoverished><In Situ><Income><Infrastructure><Institutional Review Boards><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Interview><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Latino><Lead><Leadership><Life Style><Lifestyle><Lipids><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Medical><Medical History><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Medicine><Mental Depression><Metabolic><Metformin><Modeling><Monitor><Morbidity><Myocardial Infarct><Myocardial Infarction><N,N-dimethyl-imidodicarbonimidic diamide><NIDDK><NIDDM><NIH><NMR Imaging><NMR Tomography><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Neighborhoods><Newly Diagnosed><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nuclear Magnetic Resonance Imaging><Nutracort><Nyctohemeral Rhythm><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral><Oral Glucose Tolerance Test><Outcome><Overweight><Participant><Pattern><Pb element><Pediatric Hospitals><Perception><Personal Medical History><Personal Medical History Epidemiology><Pharmaceutical Preparations><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Pilot Projects><Play><Polysomnography><Population><Position><Positioning Attribute><Poverty><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy-Induced Diabetes><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Proctocort><Productivity><Protocol><Protocols documentation><Provider><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Race><Races><Recording of previous events><Regular Insulin><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Rural Community><Sampling><Schedule><Sedentary behavior><Sedentary life-style><Site><Sleep><Sleep Monitoring><Sleep disturbances><Slow-Onset Diabetes Mellitus><Social status><Somnography><Stable Diabetes Mellitus><Standardization><Stress><Stroke><Subcellular Process><T2 DM><T2D><T2DM><Therapeutic Hormone><Time><Translational Research><Translational Science><Twenty-Four Hour Rhythm><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Universities><Urban Community><Urban Population><Urine><Visit><Weight Gain><Weight Increase><Youth><Youth 10-21><Zeugmatography><aberrant sleep><access to health services><access to services><access to treatment><accessibility to health services><active followup><adiposity><adult onset diabetes><adulthood><adverse childhood events><adverse childhood experiences><age 9><age 9 years><ages><at risk behavior><availability of services><behavioral monitoring><biobank><biologic><biorepository><blood glucose regulation><body weight gain><body weight increase><boys><brain attack><bully><bullying><cardiac infarct><cardiometabolic><cardiometabolism><care access><cerebral vascular accident><cerebrovascular accident><circadian process><circadian rhythmicity><circulatory system><clinical translation><clinically translatable><co-morbid><co-morbidity><cohort><comorbidity><computer based prediction><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><coronary attack><coronary infarct><coronary infarction><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><corpulence><creativity><critical period><daily biorhythm><demographics><depression><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><disrupted sleep><disturbed sleep><drug/agent><early onset><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><glycemic control><health equity promotion><health service access><health services availability><heart attack><heart infarct><heart infarction><heavy metal Pb><heavy metal lead><hemoglobin A1c><high risk><histories><impaired glucose tolerance><impaired sleep><improved><incomes><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><irregular sleep><juvenile><juvenile human><ketosis resistant diabetes><kids><machine based learning><malleable risk><maturity onset diabetes><member><modifiable risk><nine year old><nine years of age><novel><obesity intervention><obesity therapy><obesity treatment><optimal therapies><optimal treatments><pandemic><pandemic disease><pathophysiology><patient population><pediatric><phase 2 study><phase II study><phenotypic data><pilot study><pre-diabetes><pre-diabetic><prediabetic><predictive modeling><pregnancy diabetes><preservation><prevent><preventing><primary care practice><primary end point><primary endpoint><programs><progression risk><promote health equity><psychologic><psychological><psychosocial><racial><racial background><racial minority><racial origin><racism><recruit><response><response to therapy><response to treatment><rural patients><safety net><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><service availability><sleep disruption><sleep dysregulation><sleep measurement><sleep polysomnography><sleep/wake disruption><sleep/wake disturbance><social><social position><social role><social standing><stool><stroked><strokes><success><therapeutic response><therapeutic target><therapy response><timeline><translation research><translational investigation><translational research center><translational sciences center><treatment access><treatment program><treatment response><treatment responsiveness><treatment strategy><type 2 DM><type 2 diabetes in children><type II DM><type two diabetes><urban group><urban individual><urban people><wt gain><youngster><youth age><β-cell><β-cells><βCell>

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LORRAINE E LEVITT KATZ

CHILDREN'S HOSP OF PHILADELPHIA, PHILADELPHIA, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$610,158

FY 2026

Project Title

Assessing Diabetes Risk Origins in Teens (ADROIT)

Grant Number:

5U01DK135002-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/5/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

(<30 lines) Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin resist...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adult-Onset Diabetes Mellitus><Age><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Brittle Diabetes Mellitus><Caring><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Children (0-21)><Children's Hospital><Collaborations><Communities><Community Networks><Consensus><Continuous Glucose Monitor><Coupled><Delaware><Deterioration><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dysfunction><Early identification><Enrollment><Epidemiology><Event><Family><Feedback><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IDDM><IRB><IRBs><Incidence><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intention><Intervention><Intervention Studies><Investigation><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Modeling><NIDDM><Neighborhoods><New Jersey><Newsletter><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Overweight><Pathogenesis><Pediatric Hospitals><Pennsylvania><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Philadelphia><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Sampling><Scientist><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Specialty><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Teen><Teenagers><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><biobank><biorepository><blood glucose regulation><boys><cohort><community based practice><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><education resources><educational resources><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><kids><malleable risk><maturity onset diabetes><medical specialties><meeting><meetings><modifiable risk><nine year old><nine years of age><novel><outreach><pathophysiology><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><psychologic><psychological><recruit><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><teen years><teenage><therapeutic target><timeline><treatment strategy><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><youngster><youth age><β-cell><β-cells><βCell>

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Raj Kishore

TEMPLE UNIV OF THE COMMONWEALTH, PHILADELPHIA, PA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$604,441

FY 2026

Project Title

MyomiR-499, Exosomes and Endothelial and Endothelial Progenitor Cells dysfunction in Diabetes

Grant Number:

5R01HL169405-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Diabetes mellitus is a common chronic metabolic disease imposing great social and economic burden, and is considered as one of the major health-threats in USA and worldwide. The morbidity of critical limb ischemia (CLI) in diabetic patients is extremely high (up to 76% in so...

Research Terms

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JIAN-KANG CHEN

AUGUSTA UNIVERSITY, AUGUSTA, GA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$596,345

FY 2026

Project Title

Tubular Hypertrophy and AKI Susceptibility in Diabetes

Grant Number:

5R01DK143226-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Despite advances in treatment, acute kidney injury (AKI) patients requiring dialysis still face a high mortality rate of 50-60%, and survivors have a 28-fold increased risk of progressing to chronic kidney disease (CKD), leading to end-stage renal disease (ESRD). Diabetic patients a...

Research Terms

<3' Untranslated Regions><3'UTR><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Affect><Animals><Autophagocytosis><Binding><Cell Body><Cell Communication and Signaling><Cell Death><Cell Death Induction><Cell Signaling><Cells><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Data><Death Rate><Degradation Pathway><Degradative Pathway><Diabetes Mellitus><Dialysis><Dialysis procedure><Down-Regulation><ER stress><ESKD><ESRD><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Engineering><Exhibits><Face><Genes><Genetic><Goals><Hypertrophy><Impairment><Incidence><Intracellular Communication and Signaling><Ischemia><KO mice><Kidney><Kidney Tubules><Kidney Urinary System><Kinases><Knock-out Mice><Knockout Mice><Lead><Mediating><Metabolic Protein Degradation><Mice><Mice Mammals><Molecular><Molecular Interaction><Molecular Target><Murine><Mus><Nephrons><Null Mouse><Outcome><Pathway interactions><Patients><Pb element><Phosphorylation Site><Phosphotransferase Gene><Phosphotransferases><Play><Position><Positioning Attribute><Predisposition><Preventive><Prognosis><Protein Biosynthesis><Protein Turnover><Proteins><Proximal Kidney Tubules><Regulatory Protein Degradation><Renal tubule structure><Reperfusion Therapy><Reporting><Research><Ribosomal Peptide Biosynthesis><Ribosomal Protein Biosynthesis><Ribosomal Protein S6><Ribosomal Protein Synthesis><Risk><Role><Scheme><Severities><Signal Transduction><Signal Transduction Systems><Signaling><Site><Survivors><Susceptibility><Testing><Therapeutic><Transgenic Mice><Transphosphorylases><Tubular><Tubular formation><Uriniferous Tube><Work><acute kidney injury><autophagy><biological adaptation to stress><biological signal transduction><chronic kidney disease><co-morbid><co-morbidity><comorbidity><determine efficacy><diabetes><diabetic><diabetic patient><dialysis therapy><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><endoplasmic reticulum stress><evaluate efficacy><examine efficacy><faces><facial><heavy metal Pb><heavy metal lead><improved><inhibitor><insoluble aggregate><ischemia injury><ischemic injury><mortality rate><necrocytosis><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><non-diabetic><nondiabetic><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathway><pharmacologic><prevent><preventing><protein aggregate><protein aggregation><protein degradation><protein synthesis><public health relevance><reactioncrisis><renal><renal proximal tubule><renal tubule><reperfusion><response><social role><stress response><stressreaction><type 1 and type 2 diabetes><type I and type II diabetes>

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Zheng Dong

AUGUSTA UNIVERSITY, AUGUSTA, GA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$596,345

FY 2026

Project Title

Tubular Hypertrophy and AKI Susceptibility in Diabetes

Grant Number:

5R01DK143226-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Despite advances in treatment, acute kidney injury (AKI) patients requiring dialysis still face a high mortality rate of 50-60%, and survivors have a 28-fold increased risk of progressing to chronic kidney disease (CKD), leading to end-stage renal disease (ESRD). Diabetic patients a...

Research Terms

<3' Untranslated Regions><3'UTR><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Affect><Animals><Autophagocytosis><Binding><Cell Body><Cell Communication and Signaling><Cell Death><Cell Death Induction><Cell Signaling><Cells><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Data><Death Rate><Degradation Pathway><Degradative Pathway><Diabetes Mellitus><Dialysis><Dialysis procedure><Down-Regulation><ER stress><ESKD><ESRD><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Engineering><Exhibits><Face><Genes><Genetic><Goals><Hypertrophy><Impairment><Incidence><Intracellular Communication and Signaling><Ischemia><KO mice><Kidney><Kidney Tubules><Kidney Urinary System><Kinases><Knock-out Mice><Knockout Mice><Lead><Mediating><Metabolic Protein Degradation><Mice><Mice Mammals><Molecular><Molecular Interaction><Molecular Target><Murine><Mus><Nephrons><Null Mouse><Outcome><Pathway interactions><Patients><Pb element><Phosphorylation Site><Phosphotransferase Gene><Phosphotransferases><Play><Position><Positioning Attribute><Predisposition><Preventive><Prognosis><Protein Biosynthesis><Protein Turnover><Proteins><Proximal Kidney Tubules><Regulatory Protein Degradation><Renal tubule structure><Reperfusion Therapy><Reporting><Research><Ribosomal Peptide Biosynthesis><Ribosomal Protein Biosynthesis><Ribosomal Protein S6><Ribosomal Protein Synthesis><Risk><Role><Scheme><Severities><Signal Transduction><Signal Transduction Systems><Signaling><Site><Survivors><Susceptibility><Testing><Therapeutic><Transgenic Mice><Transphosphorylases><Tubular><Tubular formation><Uriniferous Tube><Work><acute kidney injury><autophagy><biological adaptation to stress><biological signal transduction><chronic kidney disease><co-morbid><co-morbidity><comorbidity><determine efficacy><diabetes><diabetic><diabetic patient><dialysis therapy><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><endoplasmic reticulum stress><evaluate efficacy><examine efficacy><faces><facial><heavy metal Pb><heavy metal lead><improved><inhibitor><insoluble aggregate><ischemia injury><ischemic injury><mortality rate><necrocytosis><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><non-diabetic><nondiabetic><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathway><pharmacologic><prevent><preventing><protein aggregate><protein aggregation><protein degradation><protein synthesis><public health relevance><reactioncrisis><renal><renal proximal tubule><renal tubule><reperfusion><response><social role><stress response><stressreaction><type 1 and type 2 diabetes><type I and type II diabetes>

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Michael Isaac Goran

CHILDREN'S HOSPITAL OF LOS ANGELES, LOS ANGELES, CA

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Recent

Active award

$579,857

FY 2026

Project Title

Understanding and Targeting the Pathophysiology of Youth-onset Type2 Diabetes

Grant Number:

5U01DK134984-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/21/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The DISCOVERY study aims to extensively phenotype a large, diverse cohort of youth at risk for type 2 diabetes (T2D) as they transition through puberty, a critical window for the development of metabolic dysfunction. Through comprehensive biochemical, clinical, and psychosocial assessments, the stud...

Research Terms

<12-20 years old><Adolescence><Adult-Onset Diabetes Mellitus><Behavioral><Beta Cell><Biochemical><Biologic Factor><Biological><Biological Factors><Body Composition><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Clinical assessments><Deterioration><Development><Diabetes Mellitus><Disease Progression><Disease stratification><Dissemination and Implementation><Dysfunction><Early identification><Functional disorder><Future><Insulin Cell><Insulin Secreting Cell><Intervention><Intervention Strategies><Ketosis-Resistant Diabetes Mellitus><Link><Maturity-Onset Diabetes Mellitus><Metabolic dysfunction><NIDDM><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Phenotype><Physiopathology><Preventative strategy><Prevention strategy><Preventive strategy><Psychosocial Assessment and Care><Psychosocial Factor><Puberty><Public Health><Risk><Risk Factors><Sampling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Subcellular Process><T2 DM><T2D><T2DM><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Youth><Youth 10-21><adolescence (12-20)><adult onset diabetes><biobank><biologic><biorepository><cohort><computer based prediction><design><designing><developmental><diabetes><high risk><high risk group><high risk individual><high risk people><high risk population><individualized prevention><insight><insulin sensitivity><ketosis resistant diabetes><maturity onset diabetes><pathophysiology><personalized prevention><phenotypic data><precision prevention><predictive modeling><prevent><preventing><psychosocial assessment><psychosocial care><psychosocial studies><psychosocial support><psychosocial variables><social factors><social health determinants><type 2 DM><type II DM><type two diabetes><youth age><β-cell><β-cells><βCell>

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Ryang Hwa Lee

TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, COLLEGE STATION, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$575,221

FY 2026

Project Title

Engineered extracellular vesicles derived from mesenchymal stem cells for the treatment of type 1 diabetes

Grant Number:

5R01DK136890-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Type 1 diabetes (T1D) is an autoimmune disease wherein a loss in immune tolerance leads to the initiation and progressive destruction of insulin-producing β cells. Numerous immune interventions have been reported to delay β-cell loss, but a few clinical trials have demonstrated safety and ...

Research Terms

<7S Gamma Globulin><Ablation><Acceleration><Adherent Culture><Adoptive Transfer><Antibodies><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Azides><B-Cells><B-Lymphocytes><B-cell><Beta Cell><Biodistribution><Bone-Derived Transforming Growth Factor><Brittle Diabetes Mellitus><CD3><CD3 Antigens><CD3 Complex><CD3 molecule><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><Cell Body><Cells><Clinical><Clinical Treatment Moab><Clinical Trials><Data><Data Engineering><Development><Diabetes Mellitus><Disease remission><Dose><Engineering><Engraftment><Fc Receptor><Genes><Genetic Engineering><Genetic Engineering Biotechnology><Genetic Engineering Molecular Biology><Goals><Humulin R><Hyperglycemia><IDDM><IgG><Immune><Immune Tolerance><Immune mediated therapy><Immunes><Immunoglobulin G><Immunologic Tolerance><Immunologically Directed Therapy><Immunomodulation><Immunotherapy><In Vitro><Inbred NOD Mice><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Label><Ligands><Literature><Mediating><Mesenchymal Progenitor Cell><Mesenchymal Stem Cells><Mesenchymal progenitor><Mesenchymal stromal/stem cells><Metabolic><MicroRNAs><Milk Growth Factor><Monitor><Monoclonal Antibodies><Monolayer culture><NOD Mouse><Non-Obese Diabetic Mice><Nonobese Diabetic Mouse><Novolin R><OKT3 antigen><Outcome><PD 1><PD-1><PD1><Particle Size><Patients><Plasmids><Platelet Transforming Growth Factor><Play><Pre-Clinical Model><Pre-DM><Preclinical Models><Preclinical data><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevention><Proteins><Recombinant DNA Technology><Regular Insulin><Regulatory T-Lymphocyte><Remission><Remission Induction><Reporting><Research><Role><Safety><Sudden-Onset Diabetes Mellitus><System><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><T3 Antigens><T3 Complex><T3 molecule><T4 Cells><T4 Lymphocytes><TGF B><TGF-beta><TGF-β><TGFbeta><TGFβ><Testing><Therapeutic><Therapeutic Effect><Toxic effect><Toxicities><Transforming Growth Factor beta><Transforming Growth Factor-Beta Family Gene><Treg><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Viral><antibody receptor><autoimmune condition><autoimmune disorder><autoimmunity disease><autoreactive T cell><clinical applicability><clinical application><compare to control><comparison control><developmental><diabetes><diabetic><extracellular vesicles><functional group><genetically engineered><genotoxicity><high risk><hyperglycemic><immune modulation><immune modulatory intervention><immune regulation><immune system tolerance><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune unresponsiveness><immune-based therapies><immune-based treatments><immuno therapy><immunointervention><immunologic reactivity control><immunological intervention><immunological paralysis><immunomodulatory><immunoregulation><immunoregulatory><improved><in vivo Model><insight><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><mAbs><mesenchymal stromal cell><mesenchymal stromal progenitor cells><mesenchymal-derived stem cells><miRNA><monoclonal Abs><monolayer><mouse model><murine model><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><non-diabetic><non-obese diabetic (NOD) mice><nondiabetic><nonobese diabetic (NOD) mice><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><overexpress><overexpression><polypeptide><pre-diabetes><pre-diabetic><preclinical findings><preclinical information><prediabetic><programmed cell death 1><programmed cell death protein 1><programmed death 1><rational design><regulatory T-cells><response><self-reactive T cell><side effect><sle2><social role><success><systemic lupus erythematosus susceptibility 2><thymus derived lymphocyte><type 1 diabetes onset><type I diabetes><type one diabetes><β-cell><β-cells><βCell>

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HOWARD W DAVIDSON

UNIVERSITY OF COLORADO DENVER, Aurora, CO

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$526,043

FY 2026

Project Title

Multimodal analysis of the "honeymoon period" in autoimmune diabetes

Grant Number:

5R01DK129310-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The ultimate goal of this proposal is to define composite biomarkers that can be used to improve outcomes in future type 1 diabetes (T1D) clinical trials. T1D is the major cause of diabetes in youth. It is characterized by life-long insulin insufficiency due to autoimmune mediated ß cell destruction...

Research Terms

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Heikki Hyöty

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$524,242

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Richard E Lloyd

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$524,242

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kristian F Lynch

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$524,242

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eoin McKinney

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$524,242

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph Frank Petrosino

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

High-opportunity lead · 74/100

Likely hiring

Above-average budget

Very recent

Active award

$524,242

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SHEELA NATESH MAGGE

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

High-opportunity lead · 74/100

Likely hiring

Solid budget

Very recent

Active award

$398,268

FY 2026

Project Title

The PRIORITY Study: from PRedIctiOn to pReventIon of youth-onset TYpe 2 diabetes

Grant Number:

5U01DK134975-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/22/2023

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

(<30 lines) . Youth-onset type 2 diabetes (YO-T2D) is increasingly prevalent in parallel with the obesity epidemic, yet effective treatment and prevention strategies are limited. The physiologic increase in insulin resistance occurring during puberty, in combination with obesity-related insulin res...

Research Terms

<0-11 years old><9 year old><9 years of age><Active Follow-up><Address><Adolescent><Adolescent Youth><Adolescent and Young Adult><Adolescent obesity><Adult-Onset Diabetes Mellitus><Age><Application Context><Approaches to prevention><BMI><BMI percentile><BMI z-score><Baltimore><Behavioral><Beta Cell><Biochemical><Biometrics><Biometry><Biostatistics><Blood Pressure><Body mass index><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child><Child Youth><Childhood><Children (0-21)><Children's Hospital><Clinical Research><Clinical Study><Collaborations><Consensus><Continuous Glucose Monitor><Coupled><Deterioration><Development><Diabetes Mellitus><Diet><Disease><Disorder><Down Syndrome><Dysfunction><Dyslipidemias><Early identification><Enrollment><Ensure><Epidemiology><Event><Feedback><Florida><Free Fatty Acids><Functional disorder><Funding><Future><Genetic Materials><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care><Hemoglobin A(1)><Hormonal><IRB><IRBs><Incidence><Individuals with down syndrome><Infrastructure><Institutional Review Boards><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intention><Intervention><Intervention Studies><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Langdon Down syndrome><Math Models><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical History><Metabolic><Methodology><Modeling><Mongolism><NIDDK><NIDDM><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Neighborhoods><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><OGTT><Obesity><Obesity Epidemic><Onset of illness><Oral Glucose Tolerance Test><Overweight><Pathogenesis><Pediatric Hospitals><Personal Medical History><Personal Medical History Epidemiology><Phase><Phenotype><Physical activity><Physiologic><Physiological><Physiopathology><Play><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Protocol><Protocols documentation><Puberty><QOL><Quality of life><Questionnaires><Quetelet index><Reporting><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risk Factors><Risky Behavior><Role><Rural><Sampling><Sedentary behavior><Sedentary life-style><Site><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Standardization><Stress><Subcellular Process><T2 DM><T2D><T2DM><Techniques><Time><Translational Research><Translational Science><Trisomy 21><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Urban Community><Visit><Youth><Youth 10-21><active followup><adiposity><adult onset diabetes><age 9><age 9 years><ages><at risk behavior><biobank><biorepository><blood glucose regulation><boys><cardiometabolic risk><career><child adiposity><child obesity><childhood adiposity><childhood obesity><chromosome 21 trisomy><chromosome 21 trisomy syndrome><cohort><congenital acromicria syndrome><contextual factors><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><critical period><demographics><design><designing><developmental><diabetes><diabetes risk><diets><disease onset><disorder onset><down syndrome individuals><down syndrome patients><effective therapy><effective treatment><enroll><epidemiologic><epidemiological><experience><follow up><follow-up><followed up><followup><girls><glucose control><glucose homeostasis><glucose regulation><glucose tolerance><hemoglobin A1c><high risk><impaired glucose tolerance><improved><insulin resistant><insulin sensitivity><insulin tolerance><intervention research><interventional research><interventional study><interventions research><juvenile><juvenile human><ketosis resistant diabetes><kids><malleable risk><mathematic model><mathematical model><mathematical modeling><maturity onset diabetes><modifiable risk><morbus Down><nine year old><nine years of age><novel><obese adolescents><obese children><obesity among adolescents><obesity during adolescence><obesity during childhood><obesity in adolescence><obesity in adolescents><obesity in children><outreach clinics><pathophysiology><patients with down syndrome><pediatric><pediatric obesity><people with down syndrome><phase 2 study><phase II study><phenotypic data><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><primary end point><primary endpoint><progression risk><pseudohypertrophic progressive muscular dystrophy><psychologic><psychological><recruit><response><screening><screenings><secondary end point><secondary endpoint><sedentary lifestyle><social><social role><suburban communities><therapeutic target><timeline><translation research><translational investigation><treatment strategy><trisomy 21 syndrome><type 2 DM><type II DM><type two diabetes><youngster><youth adiposity><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ashley Nicole Battarbee

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,934,914

FY 2026

Project Title

10-Year Follow-Up of the Medical Optimization and Management of Pregnancies with Overt Type 2 Diabetes (MOMPOD FU) Study

Grant Number:

1R01DK145796-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/4/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

In the U.S., more than 1 in 5 children have obesity, and 1 in 5 adolescents have prediabetes, with rapidly rising rates of youth-onset type 2 diabetes (T2D) and significant impacts on long-term health and mortality. One of the key risk factors for development of childhood obesity and diabetes is exp...

Research Terms

<0-11 years old><10 year old><10 years of age><11 year old><11 years of age><2 year old><2 years of age><21+ years old><5 year old><5 years of age><ACOG><Active Follow-up><Address><Adjuvant Therapy><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><BMI><BMI percentile><BMI z-score><Beta Cell><Birth Weight><Black><Black race><Blinded><Blood><Blood Pressure><Blood Reticuloendothelial System><Body mass index><Cardiometabolic Disease><Cardiometabolic Disorder><Cell Function><Cell Physiology><Cell Process><Cells Placenta-Tissue><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Health><Child Youth><Childhood><Childhood diabetes><Children (0-21)><Chronologic Fetal Maturity><Collaborations><Continuous Glucose Monitor><D-Glucose><DEXA><DXA><Data><Data Coordinating Center><Data Coordination Center><Development><Dextrose><Diabetes Mellitus><Diagnosis><Dimethylbiguanidine><Dimethylguanylguanidine><Drugs><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Effectiveness><Eligibility><Eligibility Determination><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Fasting><Fats><Fatty acid glycerol esters><Female><Fetal Age><Follow-Up Studies><Foundations><Functional disorder><Future><Gestation><Gestational Age><Glucose><Goals><Government><HDL Cholesterol><HDL Cholesterol Lipoproteins><Health><High Density Lipoprotein Cholesterol><High Prevalence><Hispanic><Hour><Humulin R><Hyperglycemia><Image><Incidence><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insurance><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Long-Term Effects><Longitudinal Studies><Longitudinal Surveys><Low Birth Weight Infant><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medication><Metabolic syndrome><Metformin><Methodology><Muscle><Muscle Tissue><N,N-dimethyl-imidodicarbonimidic diamide><NHANES><NIDDM><National Health and Nutrition Examination Survey><Neonatal><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Novolin R><OGTT><Obesity><Oral Glucose Tolerance Test><Outcome><Participant><Persons><Pharmaceutical Preparations><Phenotype><Physiopathology><Placebos><Placenta><Placenta Embryonic Tissue><Placentome><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy><Pregnancy in Diabetes><Pregnancy in Diabetics><Pregnant Women><Protocol Screening><Quetelet index><Randomized><Recommendation><Regular Insulin><Research><Research Specimen><Risk><Risk Factors><Safety><Sham Treatment><Shapes><Site><Skinfold Thickness><Slow-Onset Diabetes Mellitus><Specimen><Stable Diabetes Mellitus><Subcellular Process><T2 DM><T2D><T2DM><Test Result><Testing><Thinness><Time><Transmission><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Woman><Youth><Youth 10-21><active followup><adiposity><adjuvant treatment><adult onset diabetes><adult youth><adulthood><age 10><age 10 years><age 11><age 11 years><age 2><age 2 years><age 5><age 5 years><aged 2 years><aged two years><ages><alpha-Lipoprotein Cholesterol><cardiometabolic><cardiometabolism><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><design><designing><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug/agent><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><eleven year old><eleven years of age><enroll><epigenetically><expectant mother><expectant women><expecting mother><expecting women><experience><fasted><fasting glucose><fasts><five year old><five years of age><follow up><follow-up><follow-up research study><follow-up survey><followed up><followup><glycemic control><high BMI><high body mass index><hyperglycemic><imaging><improved><improved outcome><in utero><individuals who are pregnant><innovate><innovation><innovative><insight><insulin resistant><insulin tolerance><intergenerational><juvenile><juvenile human><ketosis resistant diabetes><kids><long-term study><longitudinal outcome studies><longitudinal research study><low birth weight><low birthweight><male><maternal condition><maturity onset diabetes><mortality><multidisciplinary><muscular><neonatal morbidity><neonate><newborn morbidity><obese children><obesity during childhood><obesity in children><offspring><pathophysiology><pediatric><pediatric diabetes><pediatric obesity><people who are pregnant><pre-diabetes><pre-diabetic><prediabetic><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><programs><randomisation><randomization><randomly assigned><sex><sham therapy><skin fold measurement><skin fold thickness><skinfold measurement><study with follow-up><ten year old><ten years of age><those who are pregnant><transmission process><treatment trial><two year old><two years of age><type 2 DM><type II DM><type two diabetes><waist circumference><women who are pregnant><young adult><young adult age><young adulthood><youngster><youth age><β-cell><β-cells><βCell><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Paula Catherine Chandler-Laney

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,934,914

FY 2026

Project Title

10-Year Follow-Up of the Medical Optimization and Management of Pregnancies with Overt Type 2 Diabetes (MOMPOD FU) Study

Grant Number:

1R01DK145796-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/4/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

In the U.S., more than 1 in 5 children have obesity, and 1 in 5 adolescents have prediabetes, with rapidly rising rates of youth-onset type 2 diabetes (T2D) and significant impacts on long-term health and mortality. One of the key risk factors for development of childhood obesity and diabetes is exp...

Research Terms

<0-11 years old><10 year old><10 years of age><11 year old><11 years of age><2 year old><2 years of age><21+ years old><5 year old><5 years of age><ACOG><Active Follow-up><Address><Adjuvant Therapy><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><BMI><BMI percentile><BMI z-score><Beta Cell><Birth Weight><Black><Black race><Blinded><Blood><Blood Pressure><Blood Reticuloendothelial System><Body mass index><Cardiometabolic Disease><Cardiometabolic Disorder><Cell Function><Cell Physiology><Cell Process><Cells Placenta-Tissue><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Health><Child Youth><Childhood><Childhood diabetes><Children (0-21)><Chronologic Fetal Maturity><Collaborations><Continuous Glucose Monitor><D-Glucose><DEXA><DXA><Data><Data Coordinating Center><Data Coordination Center><Development><Dextrose><Diabetes Mellitus><Diagnosis><Dimethylbiguanidine><Dimethylguanylguanidine><Drugs><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Effectiveness><Eligibility><Eligibility Determination><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Fasting><Fats><Fatty acid glycerol esters><Female><Fetal Age><Follow-Up Studies><Foundations><Functional disorder><Future><Gestation><Gestational Age><Glucose><Goals><Government><HDL Cholesterol><HDL Cholesterol Lipoproteins><Health><High Density Lipoprotein Cholesterol><High Prevalence><Hispanic><Hour><Humulin R><Hyperglycemia><Image><Incidence><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insurance><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Long-Term Effects><Longitudinal Studies><Longitudinal Surveys><Low Birth Weight Infant><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medication><Metabolic syndrome><Metformin><Methodology><Muscle><Muscle Tissue><N,N-dimethyl-imidodicarbonimidic diamide><NHANES><NIDDM><National Health and Nutrition Examination Survey><Neonatal><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Novolin R><OGTT><Obesity><Oral Glucose Tolerance Test><Outcome><Participant><Persons><Pharmaceutical Preparations><Phenotype><Physiopathology><Placebos><Placenta><Placenta Embryonic Tissue><Placentome><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy><Pregnancy in Diabetes><Pregnancy in Diabetics><Pregnant Women><Protocol Screening><Quetelet index><Randomized><Recommendation><Regular Insulin><Research><Research Specimen><Risk><Risk Factors><Safety><Sham Treatment><Shapes><Site><Skinfold Thickness><Slow-Onset Diabetes Mellitus><Specimen><Stable Diabetes Mellitus><Subcellular Process><T2 DM><T2D><T2DM><Test Result><Testing><Thinness><Time><Transmission><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Woman><Youth><Youth 10-21><active followup><adiposity><adjuvant treatment><adult onset diabetes><adult youth><adulthood><age 10><age 10 years><age 11><age 11 years><age 2><age 2 years><age 5><age 5 years><aged 2 years><aged two years><ages><alpha-Lipoprotein Cholesterol><cardiometabolic><cardiometabolism><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><design><designing><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug/agent><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><eleven year old><eleven years of age><enroll><epigenetically><expectant mother><expectant women><expecting mother><expecting women><experience><fasted><fasting glucose><fasts><five year old><five years of age><follow up><follow-up><follow-up research study><follow-up survey><followed up><followup><glycemic control><high BMI><high body mass index><hyperglycemic><imaging><improved><improved outcome><in utero><individuals who are pregnant><innovate><innovation><innovative><insight><insulin resistant><insulin tolerance><intergenerational><juvenile><juvenile human><ketosis resistant diabetes><kids><long-term study><longitudinal outcome studies><longitudinal research study><low birth weight><low birthweight><male><maternal condition><maturity onset diabetes><mortality><multidisciplinary><muscular><neonatal morbidity><neonate><newborn morbidity><obese children><obesity during childhood><obesity in children><offspring><pathophysiology><pediatric><pediatric diabetes><pediatric obesity><people who are pregnant><pre-diabetes><pre-diabetic><prediabetic><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><programs><randomisation><randomization><randomly assigned><sex><sham therapy><skin fold measurement><skin fold thickness><skinfold measurement><study with follow-up><ten year old><ten years of age><those who are pregnant><transmission process><treatment trial><two year old><two years of age><type 2 DM><type II DM><type two diabetes><waist circumference><women who are pregnant><young adult><young adult age><young adulthood><youngster><youth age><β-cell><β-cells><βCell><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jeff M Szychowski

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,934,914

FY 2026

Project Title

10-Year Follow-Up of the Medical Optimization and Management of Pregnancies with Overt Type 2 Diabetes (MOMPOD FU) Study

Grant Number:

1R01DK145796-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/4/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

In the U.S., more than 1 in 5 children have obesity, and 1 in 5 adolescents have prediabetes, with rapidly rising rates of youth-onset type 2 diabetes (T2D) and significant impacts on long-term health and mortality. One of the key risk factors for development of childhood obesity and diabetes is exp...

Research Terms

<0-11 years old><10 year old><10 years of age><11 year old><11 years of age><2 year old><2 years of age><21+ years old><5 year old><5 years of age><ACOG><Active Follow-up><Address><Adjuvant Therapy><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><BMI><BMI percentile><BMI z-score><Beta Cell><Birth Weight><Black><Black race><Blinded><Blood><Blood Pressure><Blood Reticuloendothelial System><Body mass index><Cardiometabolic Disease><Cardiometabolic Disorder><Cell Function><Cell Physiology><Cell Process><Cells Placenta-Tissue><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Health><Child Youth><Childhood><Childhood diabetes><Children (0-21)><Chronologic Fetal Maturity><Collaborations><Continuous Glucose Monitor><D-Glucose><DEXA><DXA><Data><Data Coordinating Center><Data Coordination Center><Development><Dextrose><Diabetes Mellitus><Diagnosis><Dimethylbiguanidine><Dimethylguanylguanidine><Drugs><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Effectiveness><Eligibility><Eligibility Determination><Enrollment><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exposure to><Fasting><Fats><Fatty acid glycerol esters><Female><Fetal Age><Follow-Up Studies><Foundations><Functional disorder><Future><Gestation><Gestational Age><Glucose><Goals><Government><HDL Cholesterol><HDL Cholesterol Lipoproteins><Health><High Density Lipoprotein Cholesterol><High Prevalence><Hispanic><Hour><Humulin R><Hyperglycemia><Image><Incidence><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insurance><Ketosis-Resistant Diabetes Mellitus><Knowledge><Leanness><Long-Term Effects><Longitudinal Studies><Longitudinal Surveys><Low Birth Weight Infant><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medication><Metabolic syndrome><Metformin><Methodology><Muscle><Muscle Tissue><N,N-dimethyl-imidodicarbonimidic diamide><NHANES><NIDDM><National Health and Nutrition Examination Survey><Neonatal><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Novolin R><OGTT><Obesity><Oral Glucose Tolerance Test><Outcome><Participant><Persons><Pharmaceutical Preparations><Phenotype><Physiopathology><Placebos><Placenta><Placenta Embryonic Tissue><Placentome><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy><Pregnancy in Diabetes><Pregnancy in Diabetics><Pregnant Women><Protocol Screening><Quetelet index><Randomized><Recommendation><Regular Insulin><Research><Research Specimen><Risk><Risk Factors><Safety><Sham Treatment><Shapes><Site><Skinfold Thickness><Slow-Onset Diabetes Mellitus><Specimen><Stable Diabetes Mellitus><Subcellular Process><T2 DM><T2D><T2DM><Test Result><Testing><Thinness><Time><Transmission><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Woman><Youth><Youth 10-21><active followup><adiposity><adjuvant treatment><adult onset diabetes><adult youth><adulthood><age 10><age 10 years><age 11><age 11 years><age 2><age 2 years><age 5><age 5 years><aged 2 years><aged two years><ages><alpha-Lipoprotein Cholesterol><cardiometabolic><cardiometabolism><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><design><designing><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><drug/agent><early in pregnancy><early pregnancies><early pregnancy><early stage of pregnancy><eleven year old><eleven years of age><enroll><epigenetically><expectant mother><expectant women><expecting mother><expecting women><experience><fasted><fasting glucose><fasts><five year old><five years of age><follow up><follow-up><follow-up research study><follow-up survey><followed up><followup><glycemic control><high BMI><high body mass index><hyperglycemic><imaging><improved><improved outcome><in utero><individuals who are pregnant><innovate><innovation><innovative><insight><insulin resistant><insulin tolerance><intergenerational><juvenile><juvenile human><ketosis resistant diabetes><kids><long-term study><longitudinal outcome studies><longitudinal research study><low birth weight><low birthweight><male><maternal condition><maturity onset diabetes><mortality><multidisciplinary><muscular><neonatal morbidity><neonate><newborn morbidity><obese children><obesity during childhood><obesity in children><offspring><pathophysiology><pediatric><pediatric diabetes><pediatric obesity><people who are pregnant><pre-diabetes><pre-diabetic><prediabetic><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><programs><randomisation><randomization><randomly assigned><sex><sham therapy><skin fold measurement><skin fold thickness><skinfold measurement><study with follow-up><ten year old><ten years of age><those who are pregnant><transmission process><treatment trial><two year old><two years of age><type 2 DM><type II DM><type two diabetes><waist circumference><women who are pregnant><young adult><young adult age><young adulthood><youngster><youth age><β-cell><β-cells><βCell><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Craig Evan Pollack

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

High-opportunity lead · 72/100

Likely hiring

Large award

Recent

Active award

$1,585,406

FY 2026

Project Title

The Mobility Opportunity Voucher to Eliminate Diabetes and obesity (MOVED) Study

Grant Number:

5R01DK136610-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Large budget suggests more room for personnel or project growth.

Project Abstract

Modified Project Summary An estimated 41% of adults in the US and one in five of children are estimated to have obesity; over 37 million Americans have diabetes and 96 million adults have prediabetes. The prevalence of these conditions continue to grow, highlighting the need for policies addressing...

Research Terms

<0-11 years old><21+ years old><Accelerometer><Active Follow-up><Address><Adult><Adult Human><American><Application Context><BMI><BMI percentile><BMI z-score><Behavioral><Body mass index><Characteristics><Child><Child Youth><Children (0-21)><Chronic><Chronic Disease><Chronic Illness><Collaborations><Communities><Congresses><Control Groups><Data><Data Collection><Deposit><Deposition><Diabetes Mellitus><Diet><Enrollment><Exhibits><Experimental Designs><Family><Federal Government><Fees><Food><Funding><Geography><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Benefit><Hemoglobin A(1)><Household><Housing><Impoverished><Impoverished Areas><Impoverished Regions><Intervention><Interview><Knowledge><Literature><Low Income Population><Low income><Low income group><Measures><Mediating><Mental Health><Mental Hygiene><National Government><Neighborhoods><Obesity><Outcome><Participant><Pathway interactions><Persons><Physical activity><Play><Policies><Poverty><Poverty Areas><Poverty Regions><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Psychological Health><Psychosocial Factor><Questionnaires><Quetelet index><Randomized><Randomized, Controlled Trials><Research><Role><Sampling><Security><Services><Shapes><Site><Sleep><Social support><Survey Instrument><Surveys><Testing><Time><accelerometry><access to health care><accessibility of health care><accessibility to health care><active followup><activity monitor><activity tracker><adiposity><adult adiposity><adult obesity><adulthood><adults with obesity><arm><barriers to implementation><child adiposity><child obesity><childhood adiposity><childhood obesity><chronic disorder><compare to control><comparison control><contextual factors><corpulence><design><designing><diabetes><diabetes risk><diets><disease risk><disorder risk><enroll><experience><experiment><experimental research><experimental study><experiments><falls><follow up><follow-up><followed up><followup><health care access><health care availability><health care service access><health care service availability><hemoglobin A1c><hospitalization rates><implementation barriers><implementation challenges><improved><innovate><innovation><innovative><kids><life style intervention><lifestyle intervention><low income individual><low income people><lower income families><obese children><obesity during childhood><obesity in children><obesity risk><outreach><pathway><pediatric obesity><poverty stricken areas><pre-diabetes><pre-diabetic><prediabetic><programs><psychosocial><psychosocial variables><randomisation><randomization><randomized control trial><randomly assigned><recruit><risk for obesity><risk of obesity><social><social role><social support network><treatment group><voucher><walkability><walkable><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Adolfo Garcia-Ocana

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$868,670

FY 2026

Project Title

DYRK1A inhibitors, GLP1 Receptor Agonists and Immunomodulation for Beta Cell Regeneration Therapy in Type 1 Diabetes

Grant Number:

1R01DK141874-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2026

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary Type 1 diabetes (T1D) affects ~2 million people in the US, including children. T1D is a major burden to society in terms of health costs, loss of productivity; it reduces quality of life and expectancy and causes loss of life due to acute and chronic complications. Its incidence is rising wo...

Research Terms

<0-11 years old><21+ years old><Acute><Address><Adult><Adult Human><Affect><Agonist><Anti-CD3 Antibody><Antigens><Autoimmune Mechanism><Autoimmune Process><Autoimmune Status><Autoimmunity><B9 endocrine pancreas><Beta Cell><Brittle Diabetes Mellitus><CD25><CD3><CD3 Antigens><CD3 Complex><CD3 molecule><Cell Body><Cell Death><Cell Function><Cell Growth in Number><Cell Multiplication><Cell Physiology><Cell Process><Cell Proliferation><Cell Survival><Cell Viability><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular Proliferation><Child><Child Youth><Children (0-21)><Chimera Protein><Chimeric Proteins><Chronic><Clinical><Clinical Trials><Co-Stimulator><Combined Modality Therapy><Costimulator><Data><Diabetes Mellitus><Diagnosis><Disease><Disease remission><Disorder><Dose><Dysfunction><Endocrine Pancreas><Epidermal Thymocyte Activating Factor><Ex4 peptide><Exendin 4><Expectancy><Experimental Models><Foundations><Functional disorder><Fusion Protein><Future><GLP-1 receptor><GLP-I receptor><Health><Health Care Costs><Health Costs><Heterogeneity><HuM291><Human><Humulin R><Hyperglycemia><IDDM><IL-2><IL2 Protein><IL2R><IL2RA><IL2RA gene><Immune><Immune Regulators><Immune Targeting><Immune Tolerance><Immune mediated therapy><Immune system><Immunes><Immunochemical Immunologic><Immunodeficient Mouse><Immunologic><Immunologic Tolerance><Immunological><Immunologically><Immunologically Directed Therapy><Immunologics><Immunomodulation><Immunomodulators><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><In Vitro><Inbred NOD Mice><Incidence><Inflammation><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin deficiency><Insulin-Dependent Diabetes Mellitus><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><Intervention><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kinases><Life><Life Expectancy><Lymphocyte Mitogenic Factor><Mediating><Mitogenic Factor><MoAb HuM291><Modeling><Modern Man><Molecular><Monoclonal Antibody HuM291><Multimodal Therapy><Multimodal Treatment><NOD Mouse><Natural regeneration><Nesidioblasts><Newly Diagnosed><Non-Obese Diabetic Mice><Nonobese Diabetic Mouse><Novolin R><OKT3 antigen><Onset of illness><Pancreatic Islets><Pancreatic beta Cell><Pancreatic β-Cell><Pars endocrina pancreatis><Patients><Persons><Phosphotransferase Gene><Phosphotransferases><Physiopathology><Prevention><QOL><Quality of life><Receptor Protein><Recovery><Regeneration><Regimen><Regular Insulin><Regulatory T-Lymphocyte><Remission><Replacement Therapy><Residual><Residual state><Societies><Specificity><Structure of beta Cell of islet><Subcellular Process><Sudden-Onset Diabetes Mellitus><T cell growth factor><T-Cell Growth Factor><T-Cell Stimulating Factor><T1 DM><T1 diabetes><T1D><T1DM><T3 Antigens><T3 Complex><T3 molecule><TCGFR><Testing><Therapeutic><Therapeutic Effect><Thymocyte Stimulating Factor><Time><Transphosphorylases><Transplantation><Treg><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Tyrosine Phosphorylation><Work><Youth><Youth 10-21><adulthood><autoimmune beta cell destruction><autoimmune islet destruction><autoreactive T cell><beta cell autoimmunity><cell regeneration><cellular regeneration><combination therapy><combinatorial><combined modality treatment><combined treatment><cytokine><design><designing><diabetes><diabetes mellitus therapy><diabetes therapy><disease onset><disorder onset><early onset><empowerment><exenatide><glucagon-like peptide-1 receptor><glycemic control><high risk group><high risk individual><high risk people><high risk population><hyperglycemic><immune modulation><immune modulators><immune modulatory intervention><immune regulation><immune self tolerance><immune suppression><immune suppressive activity><immune suppressive function><immune system tolerance><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune unresponsiveness><immune-based therapies><immune-based treatments><immuno therapy><immunodeficient mouse model><immunogen><immunogenicity><immunointervention><immunologic reactivity control><immunological intervention><immunological paralysis><immunomodulatory><immunomodulatory molecules><immunoregulation><immunoregulator><immunoregulatory><immunoregulatory molecules><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><in vivo><inhibitor><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulin secretion><insulitis><islet><islet autoimmunity><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><multi-modal therapy><multi-modal treatment><necrocytosis><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><pleiotropic effect><pleiotropism><pleiotropy><preservation><productivity loss><receptor><regenerate><regeneration based therapy><regeneration therapy><regenerative therapeutics><regenerative therapy><regulatory T-cells><self-reactive T cell><therapy optimization><transplant><treatment effect><treatment optimization><type 1 diabetes onset><type I diabetes><type one diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Thomas R Malek

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$868,670

FY 2026

Project Title

DYRK1A inhibitors, GLP1 Receptor Agonists and Immunomodulation for Beta Cell Regeneration Therapy in Type 1 Diabetes

Grant Number:

1R01DK141874-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2026

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary Type 1 diabetes (T1D) affects ~2 million people in the US, including children. T1D is a major burden to society in terms of health costs, loss of productivity; it reduces quality of life and expectancy and causes loss of life due to acute and chronic complications. Its incidence is rising wo...

Research Terms

<0-11 years old><21+ years old><Acute><Address><Adult><Adult Human><Affect><Agonist><Anti-CD3 Antibody><Antigens><Autoimmune Mechanism><Autoimmune Process><Autoimmune Status><Autoimmunity><B9 endocrine pancreas><Beta Cell><Brittle Diabetes Mellitus><CD25><CD3><CD3 Antigens><CD3 Complex><CD3 molecule><Cell Body><Cell Death><Cell Function><Cell Growth in Number><Cell Multiplication><Cell Physiology><Cell Process><Cell Proliferation><Cell Survival><Cell Viability><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular Proliferation><Child><Child Youth><Children (0-21)><Chimera Protein><Chimeric Proteins><Chronic><Clinical><Clinical Trials><Co-Stimulator><Combined Modality Therapy><Costimulator><Data><Diabetes Mellitus><Diagnosis><Disease><Disease remission><Disorder><Dose><Dysfunction><Endocrine Pancreas><Epidermal Thymocyte Activating Factor><Ex4 peptide><Exendin 4><Expectancy><Experimental Models><Foundations><Functional disorder><Fusion Protein><Future><GLP-1 receptor><GLP-I receptor><Health><Health Care Costs><Health Costs><Heterogeneity><HuM291><Human><Humulin R><Hyperglycemia><IDDM><IL-2><IL2 Protein><IL2R><IL2RA><IL2RA gene><Immune><Immune Regulators><Immune Targeting><Immune Tolerance><Immune mediated therapy><Immune system><Immunes><Immunochemical Immunologic><Immunodeficient Mouse><Immunologic><Immunologic Tolerance><Immunological><Immunologically><Immunologically Directed Therapy><Immunologics><Immunomodulation><Immunomodulators><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><In Vitro><Inbred NOD Mice><Incidence><Inflammation><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin deficiency><Insulin-Dependent Diabetes Mellitus><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><Intervention><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kinases><Life><Life Expectancy><Lymphocyte Mitogenic Factor><Mediating><Mitogenic Factor><MoAb HuM291><Modeling><Modern Man><Molecular><Monoclonal Antibody HuM291><Multimodal Therapy><Multimodal Treatment><NOD Mouse><Natural regeneration><Nesidioblasts><Newly Diagnosed><Non-Obese Diabetic Mice><Nonobese Diabetic Mouse><Novolin R><OKT3 antigen><Onset of illness><Pancreatic Islets><Pancreatic beta Cell><Pancreatic β-Cell><Pars endocrina pancreatis><Patients><Persons><Phosphotransferase Gene><Phosphotransferases><Physiopathology><Prevention><QOL><Quality of life><Receptor Protein><Recovery><Regeneration><Regimen><Regular Insulin><Regulatory T-Lymphocyte><Remission><Replacement Therapy><Residual><Residual state><Societies><Specificity><Structure of beta Cell of islet><Subcellular Process><Sudden-Onset Diabetes Mellitus><T cell growth factor><T-Cell Growth Factor><T-Cell Stimulating Factor><T1 DM><T1 diabetes><T1D><T1DM><T3 Antigens><T3 Complex><T3 molecule><TCGFR><Testing><Therapeutic><Therapeutic Effect><Thymocyte Stimulating Factor><Time><Transphosphorylases><Transplantation><Treg><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Tyrosine Phosphorylation><Work><Youth><Youth 10-21><adulthood><autoimmune beta cell destruction><autoimmune islet destruction><autoreactive T cell><beta cell autoimmunity><cell regeneration><cellular regeneration><combination therapy><combinatorial><combined modality treatment><combined treatment><cytokine><design><designing><diabetes><diabetes mellitus therapy><diabetes therapy><disease onset><disorder onset><early onset><empowerment><exenatide><glucagon-like peptide-1 receptor><glycemic control><high risk group><high risk individual><high risk people><high risk population><hyperglycemic><immune modulation><immune modulators><immune modulatory intervention><immune regulation><immune self tolerance><immune suppression><immune suppressive activity><immune suppressive function><immune system tolerance><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune unresponsiveness><immune-based therapies><immune-based treatments><immuno therapy><immunodeficient mouse model><immunogen><immunogenicity><immunointervention><immunologic reactivity control><immunological intervention><immunological paralysis><immunomodulatory><immunomodulatory molecules><immunoregulation><immunoregulator><immunoregulatory><immunoregulatory molecules><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><in vivo><inhibitor><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulin secretion><insulitis><islet><islet autoimmunity><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><multi-modal therapy><multi-modal treatment><necrocytosis><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><pleiotropic effect><pleiotropism><pleiotropy><preservation><productivity loss><receptor><regenerate><regeneration based therapy><regeneration therapy><regenerative therapeutics><regenerative therapy><regulatory T-cells><self-reactive T cell><therapy optimization><transplant><treatment effect><treatment optimization><type 1 diabetes onset><type I diabetes><type one diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALBERTO PUGLIESE

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$868,670

FY 2026

Project Title

DYRK1A inhibitors, GLP1 Receptor Agonists and Immunomodulation for Beta Cell Regeneration Therapy in Type 1 Diabetes

Grant Number:

1R01DK141874-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2026

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary Type 1 diabetes (T1D) affects ~2 million people in the US, including children. T1D is a major burden to society in terms of health costs, loss of productivity; it reduces quality of life and expectancy and causes loss of life due to acute and chronic complications. Its incidence is rising wo...

Research Terms

<0-11 years old><21+ years old><Acute><Address><Adult><Adult Human><Affect><Agonist><Anti-CD3 Antibody><Antigens><Autoimmune Mechanism><Autoimmune Process><Autoimmune Status><Autoimmunity><B9 endocrine pancreas><Beta Cell><Brittle Diabetes Mellitus><CD25><CD3><CD3 Antigens><CD3 Complex><CD3 molecule><Cell Body><Cell Death><Cell Function><Cell Growth in Number><Cell Multiplication><Cell Physiology><Cell Process><Cell Proliferation><Cell Survival><Cell Viability><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular Proliferation><Child><Child Youth><Children (0-21)><Chimera Protein><Chimeric Proteins><Chronic><Clinical><Clinical Trials><Co-Stimulator><Combined Modality Therapy><Costimulator><Data><Diabetes Mellitus><Diagnosis><Disease><Disease remission><Disorder><Dose><Dysfunction><Endocrine Pancreas><Epidermal Thymocyte Activating Factor><Ex4 peptide><Exendin 4><Expectancy><Experimental Models><Foundations><Functional disorder><Fusion Protein><Future><GLP-1 receptor><GLP-I receptor><Health><Health Care Costs><Health Costs><Heterogeneity><HuM291><Human><Humulin R><Hyperglycemia><IDDM><IL-2><IL2 Protein><IL2R><IL2RA><IL2RA gene><Immune><Immune Regulators><Immune Targeting><Immune Tolerance><Immune mediated therapy><Immune system><Immunes><Immunochemical Immunologic><Immunodeficient Mouse><Immunologic><Immunologic Tolerance><Immunological><Immunologically><Immunologically Directed Therapy><Immunologics><Immunomodulation><Immunomodulators><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><In Vitro><Inbred NOD Mice><Incidence><Inflammation><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin deficiency><Insulin-Dependent Diabetes Mellitus><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><Intervention><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kinases><Life><Life Expectancy><Lymphocyte Mitogenic Factor><Mediating><Mitogenic Factor><MoAb HuM291><Modeling><Modern Man><Molecular><Monoclonal Antibody HuM291><Multimodal Therapy><Multimodal Treatment><NOD Mouse><Natural regeneration><Nesidioblasts><Newly Diagnosed><Non-Obese Diabetic Mice><Nonobese Diabetic Mouse><Novolin R><OKT3 antigen><Onset of illness><Pancreatic Islets><Pancreatic beta Cell><Pancreatic β-Cell><Pars endocrina pancreatis><Patients><Persons><Phosphotransferase Gene><Phosphotransferases><Physiopathology><Prevention><QOL><Quality of life><Receptor Protein><Recovery><Regeneration><Regimen><Regular Insulin><Regulatory T-Lymphocyte><Remission><Replacement Therapy><Residual><Residual state><Societies><Specificity><Structure of beta Cell of islet><Subcellular Process><Sudden-Onset Diabetes Mellitus><T cell growth factor><T-Cell Growth Factor><T-Cell Stimulating Factor><T1 DM><T1 diabetes><T1D><T1DM><T3 Antigens><T3 Complex><T3 molecule><TCGFR><Testing><Therapeutic><Therapeutic Effect><Thymocyte Stimulating Factor><Time><Transphosphorylases><Transplantation><Treg><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Tyrosine Phosphorylation><Work><Youth><Youth 10-21><adulthood><autoimmune beta cell destruction><autoimmune islet destruction><autoreactive T cell><beta cell autoimmunity><cell regeneration><cellular regeneration><combination therapy><combinatorial><combined modality treatment><combined treatment><cytokine><design><designing><diabetes><diabetes mellitus therapy><diabetes therapy><disease onset><disorder onset><early onset><empowerment><exenatide><glucagon-like peptide-1 receptor><glycemic control><high risk group><high risk individual><high risk people><high risk population><hyperglycemic><immune modulation><immune modulators><immune modulatory intervention><immune regulation><immune self tolerance><immune suppression><immune suppressive activity><immune suppressive function><immune system tolerance><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune unresponsiveness><immune-based therapies><immune-based treatments><immuno therapy><immunodeficient mouse model><immunogen><immunogenicity><immunointervention><immunologic reactivity control><immunological intervention><immunological paralysis><immunomodulatory><immunomodulatory molecules><immunoregulation><immunoregulator><immunoregulatory><immunoregulatory molecules><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><in vivo><inhibitor><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulin secretion><insulitis><islet><islet autoimmunity><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><multi-modal therapy><multi-modal treatment><necrocytosis><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><pleiotropic effect><pleiotropism><pleiotropy><preservation><productivity loss><receptor><regenerate><regeneration based therapy><regeneration therapy><regenerative therapeutics><regenerative therapy><regulatory T-cells><self-reactive T cell><therapy optimization><transplant><treatment effect><treatment optimization><type 1 diabetes onset><type I diabetes><type one diabetes><youngster><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JENIFER ELIZABETH ALLSWORTH

UNIVERSITY OF MISSOURI KANSAS CITY, KANSAS CITY, MO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$847,068

FY 2026

Project Title

Addressing Food Access and Physcial Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

Grant Number:

1R01DK143249-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Diabetes is one of the most pressing public health challenges in the U.S., with over 98 million adults – more than one in three – already living with pre-diabetes mellitus (pre-DM), placing them at heightened risk for type 2 diabetes and its severe complications. African Ame...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><African American><African American church><African American group><African American individual><African American people><African American population><African Americans><Afro American><Afroamerican><Amputation><Area><Behavior><Black church><Blood Pressure><Body Weight decreased><Church><Clinical><Cluster randomization trial><Cluster randomized trial><Communities><Community prevention programs><Complications of Diabetes Mellitus><Curriculum><Diabetes Complications><Diabetes Mellitus><Diabetes prevention><Diabetes-Related Complications><Diabetic Complications><Diet><Dietary intake><Dimensions><Disparities><Disparity><Dose><Eating><Economics><Educational Curriculum><Effectiveness><Epidemic><Evidence based intervention><Exercise><Face><Food><Food Access><Food Assistance Programs><Food Intake><Food Selections><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Food><Health Services><Healthy Eating><Hemoglobin A(1)><Household><Image><Impoverished><Incentives><Intake><Intervention><Investments><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><Label><Language><Life Style><Lifestyle><Link><Low income><Maturity-Onset Diabetes Mellitus><Mediator><Modeling><NIDDM><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition><Nutritious food><Obesity><Outcome><Overweight><Participant><Patient Recruitments><Persons><Physical activity><Pilot Projects><Policies><Poverty><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Program Acceptability><Public Health><Randomized, Controlled Trials><Recommendation><Religiosity><Renal Disease><Research Resources><Resources><Risk><Risk Factors><Services><Site><Slow-Onset Diabetes Mellitus><Social outcome><Social support><Stable Diabetes Mellitus><Structure><Students><T2 DM><T2D><T2DM><Testing><Trust><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight Loss><Weight Reduction><adiposity><adult onset diabetes><adulthood><arm><behavior change><body weight loss><community engaged approach><community engaged approaches><community engaged strategies><community engaged strategy><community partnered approach><community partnered strategy><community setting><corpulence><cost><cost effectiveness><design><designing><diabetes><diabetes prevention program><diabetes risk><diets><economic><evidence base><experience><faces><facial><food insecure><food insecurity><food scarcity><food security><fruits and vegetables><health training><healthy food><hemoglobin A1c><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><improved><innovate><innovation><innovative><ketosis resistant diabetes><kidney disorder><lesson plans><life style intervention><lifestyle intervention><low food security><maturity onset diabetes><model building><nutrition insecurity><nutritional insecurity><participant recruitment><peer coaching><peer instruction><peer led team learning><peer mentoring><peer teaching><pilot study><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><primary outcome><process evaluation><program dissemination><programs><project dissemination><randomized control trial><renal disorder><secondary outcome><social><social culture><social determinants><social stigma><social structural><social structure><social support network><social vulnerability><socio-cultural><socio-economic><socio-economically><socio-structural><sociocultural><sociodeterminant><socioeconomically><socioeconomics><sociostructural><stigma><stressor><structural determinants><structural factors><success><systemic barrier><systemic hurdle><systemic obstacle><tailored text messaging><theories><translational study><type 2 DM><type II DM><type two diabetes><voucher><vulnerable community><weight loss program><weight loss programming><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jannette Yvonne Berkley-Patton

UNIVERSITY OF MISSOURI KANSAS CITY, KANSAS CITY, MO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$847,068

FY 2026

Project Title

Addressing Food Access and Physcial Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

Grant Number:

1R01DK143249-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Diabetes is one of the most pressing public health challenges in the U.S., with over 98 million adults – more than one in three – already living with pre-diabetes mellitus (pre-DM), placing them at heightened risk for type 2 diabetes and its severe complications. African Ame...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><African American><African American church><African American group><African American individual><African American people><African American population><African Americans><Afro American><Afroamerican><Amputation><Area><Behavior><Black church><Blood Pressure><Body Weight decreased><Church><Clinical><Cluster randomization trial><Cluster randomized trial><Communities><Community prevention programs><Complications of Diabetes Mellitus><Curriculum><Diabetes Complications><Diabetes Mellitus><Diabetes prevention><Diabetes-Related Complications><Diabetic Complications><Diet><Dietary intake><Dimensions><Disparities><Disparity><Dose><Eating><Economics><Educational Curriculum><Effectiveness><Epidemic><Evidence based intervention><Exercise><Face><Food><Food Access><Food Assistance Programs><Food Intake><Food Selections><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Food><Health Services><Healthy Eating><Hemoglobin A(1)><Household><Image><Impoverished><Incentives><Intake><Intervention><Investments><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><Label><Language><Life Style><Lifestyle><Link><Low income><Maturity-Onset Diabetes Mellitus><Mediator><Modeling><NIDDM><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition><Nutritious food><Obesity><Outcome><Overweight><Participant><Patient Recruitments><Persons><Physical activity><Pilot Projects><Policies><Poverty><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Program Acceptability><Public Health><Randomized, Controlled Trials><Recommendation><Religiosity><Renal Disease><Research Resources><Resources><Risk><Risk Factors><Services><Site><Slow-Onset Diabetes Mellitus><Social outcome><Social support><Stable Diabetes Mellitus><Structure><Students><T2 DM><T2D><T2DM><Testing><Trust><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight Loss><Weight Reduction><adiposity><adult onset diabetes><adulthood><arm><behavior change><body weight loss><community engaged approach><community engaged approaches><community engaged strategies><community engaged strategy><community partnered approach><community partnered strategy><community setting><corpulence><cost><cost effectiveness><design><designing><diabetes><diabetes prevention program><diabetes risk><diets><economic><evidence base><experience><faces><facial><food insecure><food insecurity><food scarcity><food security><fruits and vegetables><health training><healthy food><hemoglobin A1c><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><improved><innovate><innovation><innovative><ketosis resistant diabetes><kidney disorder><lesson plans><life style intervention><lifestyle intervention><low food security><maturity onset diabetes><model building><nutrition insecurity><nutritional insecurity><participant recruitment><peer coaching><peer instruction><peer led team learning><peer mentoring><peer teaching><pilot study><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><primary outcome><process evaluation><program dissemination><programs><project dissemination><randomized control trial><renal disorder><secondary outcome><social><social culture><social determinants><social stigma><social structural><social structure><social support network><social vulnerability><socio-cultural><socio-economic><socio-economically><socio-structural><sociocultural><sociodeterminant><socioeconomically><socioeconomics><sociostructural><stigma><stressor><structural determinants><structural factors><success><systemic barrier><systemic hurdle><systemic obstacle><tailored text messaging><theories><translational study><type 2 DM><type II DM><type two diabetes><voucher><vulnerable community><weight loss program><weight loss programming><wt-loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kathleen Alanna Page

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$845,922

FY 2026

Project Title

The Role of Gut-Brain Pathways on Childhood Obesity and Type 2 Diabetes Development

Grant Number:

1R01DK145940-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Childhood obesity and youth-onset type 2 diabetes (T2D) are increasing at an alarming rate, yet the underlying mechanisms remain poorly understood. Gut-derived hormones, including glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), peptide YY...

Research Terms

<0-11 years old><12-20 years old><21+ years old><7 year old><7 years of age><Address><Adolescence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Ammon Horn><Appetite><Appetite Regulation><BMI><BMI percentile><BMI z-score><Beta Cell><Body mass index><Brain><Brain Nervous System><Brain imaging><Brain region><Caloric Intake><Caring><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cellular Function><Cellular Physiology><Cellular Process><Central Lobe><Child><Child Youth><Childhood><Children (0-21)><Cornu Ammonis><Corpus Striatum><Corpus striatum structure><D-Glucose><Data><Desire for food><Development><Dextrose><Diabetes Mellitus><Diet><Dysfunction><Early Intervention><Encephalon><Endocrine Gland Secretion><Energy Intake><Exposure to><Female><Foundations><Functional disorder><Funding><GIP receptor><GLP-1><Gestational Diabetes><Gestational Diabetes Mellitus><Glp-1><Glucose><Glucose-Dependent Insulinotropic Polypeptide><Goals><Health><Hippocampus><Hormone secretion><Hormones><Hypothalamic structure><Hypothalamus><Impairment><Insula><Insula of Reil><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intervention><Intracellular Communication and Signaling><Island of Reil><Ketosis-Resistant Diabetes Mellitus><L-tyrosyl-L-tyrosine><Life Style><Lifestyle><Link><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Maturity-Onset Diabetes Mellitus><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Modeling><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrient><OGTT><Obesity><Oral><Oral Glucose Tolerance Test><Outcome><PYY Peptide><Participant><Pathway interactions><Peptide YY><Physical activity><Physiopathology><Play><Pregnancy-Induced Diabetes><Process><Quetelet index><Research><Research Design><Rewards><Risk><Risk Factors><Role><Satiation><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Striate Body><Striatum><Study Type><Subcellular Process><T2 DM><T2D><T2DM><Testing><Therapeutic Hormone><Thesaurismosis><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Tyr-Tyr><Weight Gain><Weight Increase><Work><Youth><Youth 10-21><adiposity><adolescence (12-20)><adult onset diabetes><adulthood><age 7><age 7 years><behavior influence><behavioral influence><biological signal transduction><body weight gain><body weight increase><brain pathway><brain visualization><caloric dietary content><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><critical period><cue reactivity><developmental><developmental plasticity><diabetes><diabetes risk><diets><eating cues><exposed in utero><fetal exposure><food cues><gastric inhibitory polypeptide receptor><ghrelin><glucagon-like peptide 1><glucose metabolism><glucose-dependent insulinotropic polypeptide receptor><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><hippocampal><hormonal secretion><hunger cues><hypothalamic><in utero exposure><insight><insulin resistant><insulin tolerance><intergenerational><intra-uterine environmental exposure><intrauterine environmental exposure><ketosis resistant diabetes><kids><life-style data><life-style factor><lifestyle data><lifestyle factors><long-term study><longitudinal outcome studies><longitudinal research study><maturity onset diabetes><metabolism disorder><modifiable lifestyle factors><neural><neural imaging><neural mechanism><neuro-imaging><neuroimaging><neurological imaging><neuromechanism><novel><obese children><obesity during childhood><obesity in children><obesity prevention><obesity risk><offspring><pathophysiology><pathway><pediatric><pediatric obesity><peptide tyrosine-tyrosine><precision medicine><precision-based medicine><pregnancy diabetes><prenatal><prenatal exposure><prenatal influence><prenatally exposed><prepregnancy><prevent obesity><recruit><response><risk for obesity><risk of obesity><satiety><seven year old><seven years of age><social role><striatal><study design><type 2 DM><type II DM><type two diabetes><tyrosyltyrosine><unborn><wt gain><youngster><youth age><β-cell><β-cells><βCell><♀>

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ANNY H XIANG

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$845,922

FY 2026

Project Title

The Role of Gut-Brain Pathways on Childhood Obesity and Type 2 Diabetes Development

Grant Number:

1R01DK145940-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Childhood obesity and youth-onset type 2 diabetes (T2D) are increasing at an alarming rate, yet the underlying mechanisms remain poorly understood. Gut-derived hormones, including glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), peptide YY...

Research Terms

<0-11 years old><12-20 years old><21+ years old><7 year old><7 years of age><Address><Adolescence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Ammon Horn><Appetite><Appetite Regulation><BMI><BMI percentile><BMI z-score><Beta Cell><Body mass index><Brain><Brain Nervous System><Brain imaging><Brain region><Caloric Intake><Caring><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cellular Function><Cellular Physiology><Cellular Process><Central Lobe><Child><Child Youth><Childhood><Children (0-21)><Cornu Ammonis><Corpus Striatum><Corpus striatum structure><D-Glucose><Data><Desire for food><Development><Dextrose><Diabetes Mellitus><Diet><Dysfunction><Early Intervention><Encephalon><Endocrine Gland Secretion><Energy Intake><Exposure to><Female><Foundations><Functional disorder><Funding><GIP receptor><GLP-1><Gestational Diabetes><Gestational Diabetes Mellitus><Glp-1><Glucose><Glucose-Dependent Insulinotropic Polypeptide><Goals><Health><Hippocampus><Hormone secretion><Hormones><Hypothalamic structure><Hypothalamus><Impairment><Insula><Insula of Reil><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intervention><Intracellular Communication and Signaling><Island of Reil><Ketosis-Resistant Diabetes Mellitus><L-tyrosyl-L-tyrosine><Life Style><Lifestyle><Link><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Maturity-Onset Diabetes Mellitus><Measures><Metabolic><Metabolic Diseases><Metabolic Disorder><Modeling><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrient><OGTT><Obesity><Oral><Oral Glucose Tolerance Test><Outcome><PYY Peptide><Participant><Pathway interactions><Peptide YY><Physical activity><Physiopathology><Play><Pregnancy-Induced Diabetes><Process><Quetelet index><Research><Research Design><Rewards><Risk><Risk Factors><Role><Satiation><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Sleep><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Striate Body><Striatum><Study Type><Subcellular Process><T2 DM><T2D><T2DM><Testing><Therapeutic Hormone><Thesaurismosis><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Tyr-Tyr><Weight Gain><Weight Increase><Work><Youth><Youth 10-21><adiposity><adolescence (12-20)><adult onset diabetes><adulthood><age 7><age 7 years><behavior influence><behavioral influence><biological signal transduction><body weight gain><body weight increase><brain pathway><brain visualization><caloric dietary content><child adiposity><child obesity><childhood adiposity><childhood obesity><cohort><corpulence><critical period><cue reactivity><developmental><developmental plasticity><diabetes><diabetes risk><diets><eating cues><exposed in utero><fetal exposure><food cues><gastric inhibitory polypeptide receptor><ghrelin><glucagon-like peptide 1><glucose metabolism><glucose-dependent insulinotropic polypeptide receptor><gut to brain axis><gut-brain axis><gut-brain communication><gut-brain interactions><gut-brain relationship><gut-brain signaling><hippocampal><hormonal secretion><hunger cues><hypothalamic><in utero exposure><insight><insulin resistant><insulin tolerance><intergenerational><intra-uterine environmental exposure><intrauterine environmental exposure><ketosis resistant diabetes><kids><life-style data><life-style factor><lifestyle data><lifestyle factors><long-term study><longitudinal outcome studies><longitudinal research study><maturity onset diabetes><metabolism disorder><modifiable lifestyle factors><neural><neural imaging><neural mechanism><neuro-imaging><neuroimaging><neurological imaging><neuromechanism><novel><obese children><obesity during childhood><obesity in children><obesity prevention><obesity risk><offspring><pathophysiology><pathway><pediatric><pediatric obesity><peptide tyrosine-tyrosine><precision medicine><precision-based medicine><pregnancy diabetes><prenatal><prenatal exposure><prenatal influence><prenatally exposed><prepregnancy><prevent obesity><recruit><response><risk for obesity><risk of obesity><satiety><seven year old><seven years of age><social role><striatal><study design><type 2 DM><type II DM><type two diabetes><tyrosyltyrosine><unborn><wt gain><youngster><youth age><β-cell><β-cells><βCell><♀>

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Unjali Pragya Gujral

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$824,296

FY 2026

Project Title

Putting Phenotypes and Polygenics into Practice for Diabetes Care (4PDC)

Grant Number:

1R01DK146067-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2026

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Type 2 diabetes (T2D) is a heterogeneous disease with varied clinical characteristics, treatment responses, and complication risks. However, gaps persist in understanding the biological drivers and clinical implications of T2D heterogeneity, limiting the potential to develop personal...

Research Terms

<21+ years old><Acceleration><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><Aging><Amputation><Apoplexy><Approaches to prevention><Asia><Automobile Driving><Biological><Blood Vessels><Brain Vascular Accident><C-Peptide><California><Cardiovascular Diseases><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Classification><Classification Scheme><Clinical><Colorado><Complex><Complication><Complications of Diabetes Mellitus><D-Glucose><Data><Development><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Disease><Disorder><Drugs><Dysfunction><Ethnic Group><Ethnic Origin><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity><Ethnicity People><Ethnicity Population><Europe><European><Exhibits><Fasting><Functional disorder><Genetic><Genetic Risk><Genomics><Glucose><Hawaii><Health><Heart failure><Heterogeneity><Humulin R><Individual><Insulin><Intermediary Metabolism><Intervention><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><Link><Massachusetts><Maturity-Onset Diabetes Mellitus><Measurement><Medication><Metabolic Processes><Metabolism><Molecular><NIDDM><Nature><Nephropathy><Neuropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Oregon><Outcome><Participant><Pathway interactions><Patient Representative><Performance><Pharmaceutical Preparations><Phenotype><Physiopathology><Population><Precision care><Prevention approach><Race><Races><Racial Group><Regular Insulin><Renal Disease><Reporting><Research><Retinal Diseases><Retinal Disorder><Risk><Sampling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><Subgroup><System><Systematics><T2 DM><T2D><T2DM><Techniques><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Virginia><Washington><Work><active followup><adult onset diabetes><adulthood><age associated difference><age based difference><age dependent difference><age dependent variation><age difference><age group><age related difference><age related variation><age specific difference><ages><application in practice><biologic><brain attack><cardiac failure><cardiovascular disorder><care as usual><cerebral vascular accident><cerebrovascular accident><cohort><cohort investigation><cohort research><conditioning><connecting peptide><developmental><diabetes><diabetes management><diabetes mellitus management><diabetic management><differ by age><difference across age><difference in age><driving><drug/agent><ethnic subgroup><ethnicity group><fasted><fasts><follow up><follow-up><followed up><followup><genomic data><genomic dataset><health and care delivery><health care delivery><health delivery systems><health services delivery><improved><individualized care><individualized patient care><individualized prevention><innovate><innovation><innovative><insight><investigate cohort><ketosis resistant diabetes><kidney disorder><maturity onset diabetes><member><mortality><multi-racial><multiracial><neuropathic><novel><pathophysiology><pathway><patient population><personalization of treatment><personalized care><personalized medicine><personalized patient care><personalized prevention><personalized therapy><personalized treatment><polygenetic risk scores><polygenic risk score><population based><practical application><precision medicine><precision prevention><precision-based medicine><racial><racial background><racial origin><racial population><racial subgroup><randomized, clinical trials><renal disorder><response to therapy><response to treatment><retina disease><retina disorder><retinopathy><sex><socio-economic><socio-economically><socioeconomically><socioeconomics><stroked><strokes><study cohort><survey cohort><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic response><therapy response><translational progress><translational progression><treatment as usual><treatment planning><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><usual care><variation by age><vascular>

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Darren Toh

HARVARD PILGRIM HEALTH CARE, INC., Canton, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$812,987

FY 2026

Project Title

Improving the VAlidity of LInked real-world DAta sTudiEs for Diabetes Mellitus research (VALIDATE-DM)

Grant Number:

5R01DK141534-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/13/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Individuals with diabetes and their prescribers often choose among various glucose-lowering treatments (GLTs), but information on the comparative effectiveness and safety of GLTs is limited. Most randomized controlled trials (RCTs) only compare one GLT with placebo or anothe...

Research Terms

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Jason Bini

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$808,752

FY 2026

Project Title

Longitudinal PET/MRI assessment of the pancreas in individuals at risk for and with recent onset type 1 diabetes

Grant Number:

5R01DK139213-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/13/2025

End Date:

2/28/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Over 1 million people have type 1 diabetes in the United States and greatly affects their quality of life. In vivo measurement of insulin vesicle functional capacity (IVFC) and beta cell mass (BCM) would allow tracking and monitoring of recent advances in therapies designed to preser...

Research Terms

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Steve Davidson

RUTGERS BIOMEDICAL AND HEALTH SCIENCES, Newark, NJ

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$802,015

FY 2026

Project Title

Role of a diabetes-specific circular RNA in diabetic neuropathic pain

Grant Number:

1R01DK142785-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/18/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Diabetic neuropathic pain (DNP) is a major public problem. Current successful treatment for this disorder are highly limited because most medications used are ineffective and non-specific. Changes of gene expression in primary sensory neurons of the dorsal root ganglion (DRG) are bel...

Research Terms

<3' Untranslated Regions><3'UTR><Adult-Onset Diabetes Mellitus><Afferent Neurons><Alternate Splicing><Alternative RNA Splicing><Alternative Splicing><Binding><Body Tissues><Brittle Diabetes Mellitus><C Chemokines><C-C Chemokines><CC Chemokines><CCL2><CCL2 gene><CCR2 receptor><Chemokine, CC Motif, Ligand 2><Chronic inflammatory pain><Competitive Binding><D-Glucose><Data><Dextrose><Diabetes Mellitus><Diabetic mouse><Disease><Disorder><Dorsal Root Ganglia><Drugs><Exons><Family member><Foundations><Gene Expression><GeneHomolog><Genes><Glucose><Heterogeneous-Nuclear Ribonucleoprotein L><Homolog><Homologous Gene><Homologue><Human><Hyperglycemia><Hypersensitivity><IDDM><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Ligands><MCAF><MCP-1><MCP-1 receptor><MCP1><Maturity-Onset Diabetes Mellitus><Medication><Messenger RNA><Mice><Mice Mammals><Modern Man><Molecular><Molecular Interaction><Monocyte Chemoattractant Protein-1><Monocyte Chemotactic Protein-1><Monocyte Chemotactic and Activating Factor><Monocyte Chemotactic and Activating Protein><Monocyte Chemotactive and Activating Factor><Monocyte Secretory Protein JE><Murine><Mus><NIDDM><Names><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Nociception><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Polyadenylated RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Pain><Pain Control><Pain Therapy><Pain management><Painful><Pathogenesis><Peripheral Nerves><Pharmaceutical Preparations><Pilot Projects><Proteins><QOL><Quality of life><RNA><RNA Binding><RNA Gene Products><RNA bound><RNA-Binding Proteins><Regulator Genes><Ribonucleic Acid><Role><SCYA2><STZ><Sensory Neurons><Slow-Onset Diabetes Mellitus><Spinal Ganglia><Stable Diabetes Mellitus><Streptozocin><Streptozotocin><Sudden-Onset Diabetes Mellitus><Symptoms><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Testing><Time><Tissues><Transcriptional Regulatory Elements><Translational Inhibition><Translational Repression><Translations><Trauma><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type 2 diabetic><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Type II diabetic><UTRs><Untranslated Regions><Upregulation><Work><Zanosar><adult onset diabetes><beta-Chemokines><chemotherapy><chronic and inflammatory pain><circular RNA><closed circular RNA><competitively bound><diabetes><diabetes mouse model><diabetic><diabetic patient><diet-associated obesity><diet-induced obesity><diet-related obesity><dorsal root ganglion><drug/agent><effective therapy><effective treatment><experiment><experimental research><experimental study><experiments><gamma-Chemokines><genetic trans acting element><hnRNP L><hyperglycemic><insight><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><mRNA><maturity onset diabetes><monocyte chemoattractant protein 1 receptor><name><named><naming><neuronal><neuropathic pain><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><nociceptive><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pain intervention><pain model><pain treatment><painful neuropathy><pilot study><regulatory gene><social role><surgery pain><surgical pain><therapeutic target><trans acting element><translation><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><β-Chemokines>

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Yuan-Xiang Tao

RUTGERS BIOMEDICAL AND HEALTH SCIENCES, Newark, NJ

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$802,015

FY 2026

Project Title

Role of a diabetes-specific circular RNA in diabetic neuropathic pain

Grant Number:

1R01DK142785-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/18/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Diabetic neuropathic pain (DNP) is a major public problem. Current successful treatment for this disorder are highly limited because most medications used are ineffective and non-specific. Changes of gene expression in primary sensory neurons of the dorsal root ganglion (DRG) are bel...

Research Terms

<3' Untranslated Regions><3'UTR><Adult-Onset Diabetes Mellitus><Afferent Neurons><Alternate Splicing><Alternative RNA Splicing><Alternative Splicing><Binding><Body Tissues><Brittle Diabetes Mellitus><C Chemokines><C-C Chemokines><CC Chemokines><CCL2><CCL2 gene><CCR2 receptor><Chemokine, CC Motif, Ligand 2><Chronic inflammatory pain><Competitive Binding><D-Glucose><Data><Dextrose><Diabetes Mellitus><Diabetic mouse><Disease><Disorder><Dorsal Root Ganglia><Drugs><Exons><Family member><Foundations><Gene Expression><GeneHomolog><Genes><Glucose><Heterogeneous-Nuclear Ribonucleoprotein L><Homolog><Homologous Gene><Homologue><Human><Hyperglycemia><Hypersensitivity><IDDM><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Ligands><MCAF><MCP-1><MCP-1 receptor><MCP1><Maturity-Onset Diabetes Mellitus><Medication><Messenger RNA><Mice><Mice Mammals><Modern Man><Molecular><Molecular Interaction><Monocyte Chemoattractant Protein-1><Monocyte Chemotactic Protein-1><Monocyte Chemotactic and Activating Factor><Monocyte Chemotactic and Activating Protein><Monocyte Chemotactive and Activating Factor><Monocyte Secretory Protein JE><Murine><Mus><NIDDM><Names><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Nociception><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Polyadenylated RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Pain><Pain Control><Pain Therapy><Pain management><Painful><Pathogenesis><Peripheral Nerves><Pharmaceutical Preparations><Pilot Projects><Proteins><QOL><Quality of life><RNA><RNA Binding><RNA Gene Products><RNA bound><RNA-Binding Proteins><Regulator Genes><Ribonucleic Acid><Role><SCYA2><STZ><Sensory Neurons><Slow-Onset Diabetes Mellitus><Spinal Ganglia><Stable Diabetes Mellitus><Streptozocin><Streptozotocin><Sudden-Onset Diabetes Mellitus><Symptoms><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Testing><Time><Tissues><Transcriptional Regulatory Elements><Translational Inhibition><Translational Repression><Translations><Trauma><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type 2 diabetic><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Type II diabetic><UTRs><Untranslated Regions><Upregulation><Work><Zanosar><adult onset diabetes><beta-Chemokines><chemotherapy><chronic and inflammatory pain><circular RNA><closed circular RNA><competitively bound><diabetes><diabetes mouse model><diabetic><diabetic patient><diet-associated obesity><diet-induced obesity><diet-related obesity><dorsal root ganglion><drug/agent><effective therapy><effective treatment><experiment><experimental research><experimental study><experiments><gamma-Chemokines><genetic trans acting element><hnRNP L><hyperglycemic><insight><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><mRNA><maturity onset diabetes><monocyte chemoattractant protein 1 receptor><name><named><naming><neuronal><neuropathic pain><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><nociceptive><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pain intervention><pain model><pain treatment><painful neuropathy><pilot study><regulatory gene><social role><surgery pain><surgical pain><therapeutic target><trans acting element><translation><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><β-Chemokines>

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William Benjamin Horton

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$788,831

FY 2026

Project Title

Development of a ketone-aware automated insulin delivery system to enable safe use of sodium-glucose cotransporter inhibitors in people with type 1 diabetes

Grant Number:

1R01DK145849-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2026

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Despite recent advances in diabetes treatment and technology (e.g., automated insulin delivery [AID] systems), achieving recommended glycemic targets is still difficult for people with type 1 diabetes (T1D) and, worrisomely, T1D confers substantial cardiorenal risk even when conventi...

Research Terms

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ZHENQI LIU

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$782,459

FY 2026

Project Title

Impact of obesity on microvascular insulin action and cardiorespiratory fitness in Type 1 Diabetes

Grant Number:

1R01DK141617-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract The overall relative risk of cardiovascular disease (CVD) remains 3- to 10-fold higher in individuals with type 1 diabetes (T1D), despite intensive glycemic control and traditional CVD risk management. Epidemiologic studies indicate that more than 60% of individuals with T1D...

Research Terms

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YU KUEI LIN

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$780,220

FY 2026

Project Title

A Scalable and Effective Digital Behavioral Intervention for Mitigating Hypoglycemia among People with Diabetes: An Optimization Trial

Grant Number:

1R01DK142830-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/27/2026

End Date:

1/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Level 2 hypoglycemia (i.e., low blood glucose) can affect one’s daily life; generate fear and psychological distress; and lead to brain dysfunction, heart complications, and even death. People living with type 1 diabetes (T1D) are particularly susceptible to developing Level 2 hypogl...

Research Terms

<21+ years old><Active Follow-up><Acute><Address><Adult><Adult Human><Affect><American><Arrhythmia><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Belief><Blood Glucose><Blood Sugar><Brain><Brain Nervous System><Brittle Diabetes Mellitus><Cardiac Arrhythmia><Caring><Cessation of life><Characteristics><Clinical Trials><Complication><Conditioning Therapy><Confusion><Confusional State><Continuous Glucose Monitor><Critical Care><D-Glucose><Dangerousness><Data><Death><Decision Making><Detection><Dextrose><Diabetes Mellitus><ED visit><ER visit><Education><Educational aspects><Effectiveness><Effectiveness of Interventions><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Encephalon><Equilibrium><Event><Face><Fear><Fright><Glucose><Goals><Heart><Heart Arrhythmias><Hospital Admission><Hospitalization><Humulin R><Hyperglycemia><Hypoglycemia><IDDM><Individual><Insulin><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intervention><Interview><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Life><Measures><Mental Confusion><Methodology><Monitor><Novolin R><Participant><Patients><Performance><Persons><Population><Predisposition><Protocol><Protocols documentation><Randomized><Regular Insulin><Risk><Self Management><Self-reflection><Structure><Sudden-Onset Diabetes Mellitus><Susceptibility><Symptoms><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Text Messaging><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Work><abnormal brain function><active followup><adulthood><balance><balance function><behavior intervention><behavioral intervention><brain dysfunction><brain impairment><cardiac function><care as usual><clinical care><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><design><designing><diabetes><diabetes control><diabetes management><diabetes mellitus control><diabetes mellitus management><diabetic management><digital><digital based behavioral intervention><digital behavioral intervention><digital health behavioral intervention><digital intervention><dysfunctional brain><evidence base><experience><faces><facial><feasibility testing><follow up><follow-up><followed up><followup><function of the heart><future implementation><heart function><high risk><hyperglycemic><hypoglycemic><hypoglycemic episodes><improved><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><intervention program><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><multidisciplinary><multiphase optimization strategy><novel><patient registry><pilot test><primary outcome><programs><psychoeducation><psychological distress><randomisation><randomization><randomly assigned><recruit><short message service><skill acquisition><skill development><sms messaging><sms messaging intervention><standard of care><text based intervention><text intervention><text messaging based intervention><text messaging intervention><texting><treatment as usual><type I diabetes><type one diabetes><usual care><work group><working group>

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Brian T Fife

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$760,277

FY 2026

Project Title

Determine how a normal microbial environment protects against autoimmune diabetes

Grant Number:

1R01AI195876-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/20/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY Autoimmune type 1 diabetes (T1D) is caused by the T cell-mediated destruction of insulin producing beta (β) cells in the pancreas. The incidence of T1D is rising globally. This is thought to be linked to early life exposure to microbes, environmental pollutants, and even diet. Viral infecti...

Research Terms

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Julie Paik

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$745,846

FY 2026

Project Title

Optimizing the Safety of the Newer Diabetes Medications in Patients with Diabetes and Kidney Disease

Grant Number:

5R01DK135706-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/19/2024

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Sodium glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide 1 receptor agonists (GLP- 1RA) are rapidly changing the therapeutic landscape for patients with diabetes and kidney disease, but are underutilized in high-risk populations. Randomized controlled trials (RCTs) have robustly ...

Research Terms

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Raimund Ingo Herzog

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$742,174

FY 2026

Project Title

Mechanism of ultrasound neuromodulation effects on glucose homeostasis and diabetes

Grant Number:

5R01DK131127-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary The dominant and increasingly evident role of the central nervous system in glucose metabolism regulation remains an attractive therapeutic target for diabetes. Brain stem and hypothalamic coordinating centers of feeding and glucose homeostasis have been well characterized over the ...

Research Terms

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Michael A Silverman

CHILDREN'S HOSP OF PHILADELPHIA, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$721,401

FY 2026

Project Title

Leveraging early-life microbes to prevent type 1 diabetes

Grant Number:

5R01DK133453-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Type 1 diabetes (T1D) is an autoimmune disease that affects millions of people worldwide. The incidence of T1D is rising, especially in young children. Although significant progress has been made to predict who is at risk for developing T1D, there are no effective therapies to preven...

Research Terms

<0-11 years old><21+ years old><Adult><Adult Human><Affect><Alleles><Allelomorphs><Anatomic Sites><Anatomic structures><Anatomy><Antigen Presentation><Antigens><Autoantigens><Autoimmune Diabetes><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Bacteria><Birth><Brittle Diabetes Mellitus><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><Cell Body><Cells><Child><Child Youth><Childhood><Children (0-21)><Class II Antigens><Class II Major Histocompatibility Antigens><Communities><Complex><Data><Development><Diabetes Mellitus><Disease><Disorder><Environmental Factor><Environmental Risk Factor><Exposure to><GI microbiome><Generalized Growth><Genetic><Genetic Models><Germ-Free><Gnotobiotic><Gnotobiotics><Goals><Growth><HL-A Antigens><HLA Antigens><Haplotypes><Histocompatibility Antigens Class II><Histocompatibility Complex><Histocompatibility Complices><Human><Human Leukocyte Antigens><I-A Antigen><IDDM><Ia Antigens><Ia-Like Antigens><Immune><Immune Response Antigens><Immune response><Immune system><Immune-Response-Associated Antigens><Immunes><Immunization><Immunomodulation><In Vitro><Inbred NOD Mice><Incidence><Insulin-Dependent Diabetes Mellitus><Intestinal><Intestines><Investigation><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocyte Antigens><Life><MHC Class II Molecule><MHC Class II Protein><MHC class II antigen><Major Histocompatibility Complex><Major Histocompatibility Complex Class II><Major Histocompatibility Complices><Mediating><Metabolic><Mice><Mice Mammals><Microbe><Modeling><Modern Man><Mucosa><Mucosal Tissue><Mucous Membrane><Murine><Mus><NOD Mouse><Non-Obese Diabetic Mice><Nonobese Diabetic Mouse><Parturition><Pathway interactions><Peptides><Peripheral><Persons><Phylogenetic Analysis><Phylogenetics><Predisposition><Property><Proteins><Publishing><Regulatory T-Lymphocyte><Research><Risk><Role><Self-Antigens><Shapes><Site><Sudden-Onset Diabetes Mellitus><Susceptibility><System><Systems Development><T cell receptor repertoire sequencing><T cell receptor sequencing><T cell response><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><T4 Cells><T4 Lymphocytes><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><Testing><Therapeutic><Time><Tissue Growth><Transgenic Mice><Transgenic Organisms><Transmission><Treg><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Weaning><Work><adulthood><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><beta cell autoimmunity><bowel><community microbes><developmental><diabetes><diabetes pathogenesis><digestive tract microbiome><early life exposure><effective therapy><effective treatment><enteric microbiome><environmental risk><gastrointestinal homeostasis><gastrointestinal microbiome><genetic linkage><gut microbes><gut microbial species><gut microbiome><gut-associated microbiome><host microbiota><host microflora><host response><imaging mass spectrometry><immune modulation><immune regulation><immune system response><immunogen><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><in vivo><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intestinal biome><intestinal homeostasis><intestinal microbes><intestinal microbiome><islet autoimmunity><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><mass spectrometric imaging><member><metabolism measurement><metabolomics><metabonomics><microbe community><microbial><microbial antigen><microbial community><microbial consortia><microbial flora><microbial interaction><microbial products><microbiome><microbiota><microflora><microorganism antigen><microorganism community><microorganism interaction><mouse model><multispecies consortia><murine model><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><ontogeny><pathway><pediatric><polymicrobial community><prevent><preventing><protective effect><rational design><regulatory T-cells><resident microbes><resident microflora><response><restraint><social role><spatial temporal imaging><spatial temporal mapping><spatiotemporal imaging><spatiotemporal mapping><thymus derived lymphocyte><tool><transgenic><transmission process><type I diabetes><type one diabetes><validation studies><youngster>

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Yunmeng Liu

UNIV OF ARKANSAS FOR MED SCIS, LITTLE ROCK, AR

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$717,457

FY 2026

Project Title

Metabolic Rewiring of T Cells Bridges Diabetes to Hypertension

Grant Number:

1R01DK145683-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2026

End Date:

11/30/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY / ABSTRACT Metabolic syndrome persists as a leading cause of morbidity and mortality among adults in the United States. Specifically, the co-existence of diabetes and hypertension, hallmark components of metabolic syndrome, stand as primary contributors to cardiovascular disease and...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Attention><Attenuated><Autocrine Systems><Automobile Driving><Blood Plasma><Blood Pressure><Body Tissues><Bone-Derived Transforming Growth Factor><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Calcium><Cardiac Diseases><Cardiac Disorders><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cessation of life><Chronic><Complex><Coupled><D-Glucose><Dangerousness><Death><Development><Dextrose><Diabetes Mellitus><Diabetic mouse><Disease><Disorder><Dysfunction><Event><Feedback><Functional disorder><Glucose><Health><Heart Diseases><Heart Vascular><High Fat Diet><Humulin R><Hyperinsulinemia><Hyperinsulinism><Hypertension><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><Immune><Immune Interferon><Immunes><Immunology><Immunotherapeutic agent><Infiltration><Insulin><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin-Dependent Tyrosine Protein Kinase><Interferon Gamma><Interferon Type II><Intermediary Metabolism><Intervention><Intracellular Communication and Signaling><Investigation><KO mice><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Link><Mature T-Cell><Mature T-Lymphocyte><Maturity-Onset Diabetes Mellitus><Mediating><Metabolic><Metabolic Activation><Metabolic Pathway><Metabolic Processes><Metabolic syndrome><Metabolism><Mice><Mice Mammals><Milk Growth Factor><Modeling><Morbidity><Murine><Mus><NCC gene><NCC protein><NCCT><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Null Mouse><Obesity><Pathogenesis><Pathogenicity><Pathway interactions><Patients><Persons><Physiopathology><Plasma><Plasma Serum><Platelet Transforming Growth Factor><Process><Production><Purine Receptors><Purinergic Receptors><Purinoceptor><Receptor Protein><Receptor Signaling><Regular Insulin><Reporting><Research><Residencies><Reticuloendothelial System, Serum, Plasma><Role><SLC12A3><SLC12A3 gene><Signal Induction><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Slow-Onset Diabetes Mellitus><Sodium Chloride><Solute Carrier Family 12 (Sodium/Chloride Transporter), Member 3><Source><Stable Diabetes Mellitus><Stimulus><Structure><T-Cell Activation><T-Cells><T-Lymphocyte><T2 DM><T2D><T2DM><T8 Cells><T8 Lymphocytes><TGF B><TGF-beta><TGF-beta Receptors><TGF-β><TGF-β Receptors><TGFbeta><TGFβ><TSC gene><TSC protein><Testing><Thiazide-Sensitive Sodium-Chloride Cotransporter><Thiazide-Sensitvie Na-Cl Cotransporter><Time><Tissues><Transforming Growth Factor beta><Transforming Growth Factor beta Receptors><Transforming Growth Factor β Receptors><Transforming Growth Factor-Beta Family Gene><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Wild Type Mouse><activate T cells><adiposity><adult onset diabetes><adulthood><aerobic glycolysis><attenuate><attenuates><autocrine><biological signal transduction><blood pressure elevation><cardiovascular disorder><cardiovascular function><cardiovascular risk><cardiovascular risk factor><circulatory system><co-morbid><co-morbidity><comorbidity><corpulence><cytokine><developmental><diabetes><diabetes mouse model><diabetes pathogenesis><diabetes risk><diabetic><driving><elevated blood pressure><experiment><experimental research><experimental study><experiments><extracellular><feeding><glucose metabolism><glucose uptake><heart disorder><high blood pressure><hyperpiesia><hyperpiesis><hypertensive><hypertensive disease><hypertensive disorder><immune drugs><immune-based therapeutics><immunologic therapeutics><immunotherapeutics><immunotherapy agent><in vivo><increase in blood pressure><increased blood pressure><innovate><innovation><innovative><insight><interdisciplinary approach><ketosis resistant diabetes><lFN-Gamma><maturity onset diabetes><metabolic profile><mortality><mouse model><multidisciplinary approach><murine model><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathophysiology><pathway><prevent><preventing><public health relevance><receptor><renal><salt><salt hypertension><salt induced hypertension><salt sensitive hypertension><social role><sodium-chloride cotransporter><sodium-chloride transporter><thiazide-sensitive Na-Cl cotransporter><thiazide-sensitive cotransporter><thymus derived lymphocyte><type 2 DM><type II DM><type two diabetes><wildtype mouse>

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ERIN S LEBLANC

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$703,883

FY 2026

Project Title

Sleep for Health: A randomized clinical trial examining the effects of cognitive behavioral therapy for insomnia on diabetes risk

Grant Number:

5R01DK132229-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Type 2 diabetes mellitus (T2D) is a major cause of blindness, kidney failure, cardiovascular disease, amputations, reduced quality of life, and premature death in the United States, and it is expected that one in three Americans will have T2D by 2050. To stem the tide of thi...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aeroseb-HC><Affect><American><Amputation><Behavioral><Blindness><Blood Glucose><Blood Sample><Blood Sugar><Blood specimen><Body Weight decreased><Cardiovascular Diseases><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Cessation of life><Cetacort><Chronic><Clinical><Cognition Therapy><Cognitive Psychotherapy><Cognitive Therapy><Cognitive treatment><Continuous Glucose Monitor><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><D-Glucose><Data><Death><Dermacort><Dextrose><Diabetes Mellitus><Diabetes prevention><Diagnosis><Diet><Eating><Educational Materials><Educational workshop><Eldecort><Emotional Depression><Equilibrium><Exercise><Feasibility Studies><Food Intake><Future><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health system><Healthy Eating><Hemoglobin A(1)><Heterogeneity><Hour><Hydrocortisone><Hydrocortone><Hyperglycemia><Hytone><Individual><Inflammation><Insomnia><Insomnia Disorder><Insulin Resistance><Intake><Intervention><Intervention Studies><Ketosis-Resistant Diabetes Mellitus><Kidney Failure><Kidney Insufficiency><Laboratory Study><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Metabolic><Modeling><Moods><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutracort><OGTT><Obesity><Oral Glucose Tolerance Test><Outcome><Pancreas><Pancreatic><Participant><Pathway interactions><Patient Education><Patient Instruction><Patient Training><Patients><Persons><Physical activity><Physiologic><Physiological><Pilot Projects><Population><Population Study><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Proctocort><QOL><Quality of life><Randomized><Renal Failure><Renal Insufficiency><Research><Rewards><Risk><Risk Factors><Sampling><Sleep><Sleep Deprivation><Sleep Disorders><Sleep disturbances><Sleeplessness><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Subcellular Process><T2 DM><T2D><T2DM><Testing><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Weight Gain><Weight Increase><Weight Loss><Weight Reduction><Work><Workshop><aberrant sleep><adipocytokines><adipokines><adiposity><adult onset diabetes><adulthood><anxiety symptoms><anxious symptom><arm><balance><balance function><body weight gain><body weight increase><body weight loss><cardiovascular disorder><clinical significance><clinically significant><cognitive behavior intervention><cognitive behavior modification><cognitive behavior therapy><cognitive behavioral intervention><cognitive behavioral modification><cognitive behavioral therapy><cognitive behavioral treatment><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><deficient sleep><depression symptom><depressive><depressive symptoms><diabetes><diabetes risk><diets><digital><disrupted sleep><disturbed sleep><energy density><evidence base><fall asleep><fasting glucose><food craving><glucose tolerance><hemoglobin A1c><hyperglycemic><impaired sleep><improved><improvement on sleep><inadequate sleep><indexing><insufficient sleep><insulin resistant><insulin tolerance><intervention arm><intervention effect><intervention research><interventional research><interventional study><interventions research><irregular sleep><ketosis resistant diabetes><malleable risk><maturity onset diabetes><moderate-to-vigorous physical activity><modifiable risk><pathway><pilot study><poor sleep><population research study><population survey><population-based study><population-level study><pre-diabetes><pre-diabetic><prediabetic><premature><prematurity><prevent><preventing><primary outcome><programs><quality of sleep><randomisation><randomization><randomized, clinical trials><randomly assigned><recruit><restoration><secondary outcome><sedentary><sleep amount><sleep debt><sleep deficiency><sleep deficit><sleep diseases><sleep disruption><sleep duration><sleep dysfunction><sleep dysregulation><sleep episode><sleep health><sleep hygiene><sleep illness><sleep improvement><sleep insufficiency><sleep interval><sleep length><sleep loss><sleep onset><sleep period><sleep problem><sleep quality><sleep quantity><sleep time><sleep wellness><sleep/wake disruption><sleep/wake disturbance><standard of care><stem><time asleep><time during sleep><time in sleep><time spent asleep><time spent sleeping><tool><treatment arm><trend><type 2 DM><type II DM><type two diabetes><vision loss><visual loss><web site><website><wt gain><wt-loss>

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Davene Renee Wright

HARVARD PILGRIM HEALTH CARE, INC., Canton, MA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$700,433

FY 2026

Project Title

InvesT1D: Promoting Adolescent Investment in Diabetes Care

Grant Number:

5R01DK136090-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/26/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Over 80% of adolescents with type 1 diabetes (T1D) struggle to achieve good glycemic control, placing them at risk for acute and chronic complications. Instilling good T1D management practices in adolescence can set a pattern into adulthood, improving long-term health while reducing future burden on...

Research Terms

<12-20 years old><18 year old><18 years of age><21+ years old><Acute><Address><Adherence><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Adverse Experience><Adverse event><Award><Behavior><Behavioral><Blindness><Brittle Diabetes Mellitus><Caring><Childhood><Chronic><Chronic Disease><Chronic Illness><Clinical><Complications of Diabetes Mellitus><Conflict><Conflict (Psychology)><Continuous Glucose Monitor><Cost Analyses><Cost Analysis><Cost Savings><Data><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Acidosis><Diabetic Complications><Diabetic Ketoacidosis><Diabetic Ketosis><Economic Burden><Economics><Ethical Analyses><Ethical Analysis><Ethics><Evaluation><Family><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Grant><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Benefit><Health Care><Health Care Systems><Health Care Utilization><Health Psychology><Health behavior><Health system><Hemoglobin A(1)><IDDM><Incentives><Individual><Insulin-Dependent Diabetes Mellitus><Intervention><Interview><Investments><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kidney Failure><Kidney Insufficiency><Laws><Length><Methodology><Methods><Modeling><Outcome><Paper><Patient Preferences><Patients><Pattern><Policies><Policy Analyses><Policy Analysis><Politics><Population><Practice Management><Privatization><Protocol><Protocols documentation><QALY><QOL><Quality of life><Quality-Adjusted Life Expectancy><Quality-Adjusted Life Years><Randomized><Randomized, Controlled Trials><Recommendation><Regimen><Renal Failure><Renal Insufficiency><Research><Risk><Risk Taking><Sampling><Self Management><Structure><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Time><Treatment Protocols><Treatment Regimen><Treatment Schedule><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><adolescence (12-20)><adulthood><age 18><age 18 years><assess cost><behavioral health><care as usual><caregiver quality of life><chronic disorder><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><cost assessment><cost effective><cost effectiveness><cost evaluation><cost-effectiveness indices><cost-effectiveness ratio><dashboard><design><designing><determine efficacy><developmental><diabetes><diabetes distress><diabetes management><diabetes mellitus management><diabetes self-care><diabetes self-management><diabetes-related distress><diabetes-specific distress><diabetic ketoacidotic><diabetic management><distress related to diabetes><distress specific to diabetes><economic><economic analysis><economic assessment><economic evaluation><economic impact><economic outcome><effectiveness/implementation hybrid study><effectiveness/implementation study><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><eighteen year old><eighteen years of age><ethical><evaluate cost><evaluate efficacy><examine cost><examine efficacy><experiment><experimental research><experimental study><experiments><financial incentive><financial reward><flexibility><flexible><glycemic control><health and care delivery><health care delivery><health care service use><health care service utilization><health delivery systems><health economics><health plan><health plans><health related behavior><health related quality of life><health services delivery><hemoglobin A1c><high risk><improved><incentive program><incentive-based intervention><incentive-based program><incremental cost-effectiveness><incrementally cost effective><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><intervention arm><juvenile><juvenile diabetes><juvenile diabetes mellitus><juvenile human><ketosis prone diabetes><markov model><model-based simulation><models and simulation><monetary incentive><patient centered><patient oriented><payment><pediatric><policy evaluation><preference><pressure><prevent><preventing><primary outcome><programs><prospective><psychosocial development><quality of life for caregivers><randomisation><randomization><randomized control trial><randomly assigned><social><treatment arm><treatment as usual><type I diabetes><type one diabetes><usual care><vision loss><visual loss><willingness to pay>

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Abeer M Mohamed

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$694,666

FY 2026

Project Title

Role of Adiposomes in Diabetes-Associated Endothelial Dysfunction and Restorative Effects of Exercise and Metabolic Surgery

Grant Number:

5R01HL161386-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT The development of type II diabetes (T2D) is strongly associated with obesity, and both are well-established risk factors for cardiovascular disease. Vascular dysfunction is an early event in developing cardiovascular disease in obese diabetic (OB-T2D) patients. Therefore, we set our long-t...

Research Terms

<21+ years old><Adipocytes><Adipose Cell><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aerobic Activity><Aerobic Exercise><Aerobic Training><Aerobic fitness><Affect><Asialogangliosides><Autoregulation><Biological><Biopsy><Blood Vessels><Body Tissues><Body Weight decreased><Cardiovascular Diseases><Caveolae><Caveolas><Cell Body><Cell Communication and Signaling><Cell Protection><Cell Signaling><Cell membrane><Cell surface><Cell to Cell Communication and Signaling><Cell-Cell Signaling><Cells><Ceramides><Characteristics><Chemicals><Communication><Cytoplasmic Membrane><Cytoprotection><D-Glucose><Data><Development><Dextrose><Diabetes Mellitus><ENOS><Endothelial Cells><Endothelial Nitric Oxide Synthase><Endothelium><Event><Exercise><Fat Cells><Fatty Tissue><Glucose><Glycosphingolipids><Goals><Homeostasis><Human><Hyperglycemia><Hypoxia><Hypoxic><In Vitro><Individual><Inflammation><Insulin Resistance><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Leanness><Lipids><Lipocytes><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Membrane><Metabolic><Metabolic Glycosylation><MicroRNAs><Modern Man><Molecular><NIDDM><NOS3><NOS3 gene><Nitric Oxide Synthase 3><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Operative Procedures><Operative Surgical Procedures><Outcome><Oxygen Deficiency><Pathogenesis><Pathway interactions><Patients><Permeability><Phosphorylation><Physical activity><Physiological Homeostasis><Plasma Membrane><Predisposing Factor><Process><Production><Property><Protein Phosphorylation><Proteins><Randomized><Research><Risk><Role><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Sphingoglycolipids><Stable Diabetes Mellitus><Structure><Surface><Surgical><Surgical Interventions><Surgical Procedure><T2 DM><T2D><T2DM><Testing><Therapeutic><Therapeutic Intervention><Thinness><Tissues><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Type III nitric oxide synthase><Vascular Diseases><Vascular Disorder><Visceral><Weight Loss><Weight Reduction><adipose><adiposity><adult onset diabetes><adulthood><angiogenesis><arteriole><atherogenesis><bariatric surgery><biologic><biological signal transduction><blood vessel disorder><body weight loss><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><co-morbid><co-morbidity><comorbidity><corpulence><cytoprotective><developmental><diabetes><diabetic><effectiveness testing><endothelial dysfunction><exercise training><extracellular vesicles><fat metabolism><gastric banding><gastric bypass surgery><glycosylation><hyperglycemic><implantable gastric stimulation banding><improved><insulin resistant><insulin tolerance><intercellular communication><intervention therapy><ketosis resistant diabetes><lipid metabolism><maturity onset diabetes><membrane structure><miRNA><mimetics><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><obesity surgery><pathway><plasmalemma><preconditioning><prevent><preventing><randomisation><randomization><randomly assigned><sensor><shear stress><social><social role><src Kinases><src Protein-Tyrosine Kinases><src Tyrosine Kinases><src-Family Kinases><src-Family Tyrosine Kinases><stomach stapling><subcutaneous><subdermal><surgery><synergism><transcytosis><type 2 DM><type II DM><type two diabetes><uptake><vascular><vascular dysfunction><vascular endothelial dysfunction><vasculopathy><weight loss intervention><weight loss surgery><weight loss therapy><weight loss treatment><white adipose tissue><wt-loss><yellow adipose tissue>

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Manuel F Navedo

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$681,632

FY 2026

Project Title

Mechanisms of VSM dysfunction in diabetes and HFpEF

Grant Number:

5R01HL171014-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract . Vascular complications associated with lifestyle-related diseases, such as diabetes, contribute to an increased risk of hypertension, coronary artery disease, and heart failure associated with preserved ejection fraction (HFpEF). These vascular complications may involve, at least in part,...

Research Terms

<3'5'-cyclic ester of AMP><A kinase anchoring protein><AKAP><Address><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine Cyclic Monophosphate-Dependent Protein Kinases><Adenosine Triphosphate><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Adenylpyrophosphate><Animal Model><Animal Models and Related Studies><Animals><Arteries><Biochemistry><Biological Chemistry><Biosensor><Blood Glucose><Blood Pressure><Blood Sugar><Blood Vessels><Blood flow><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Complex><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Cyclic AMP><Cyclic AMP-Dependent Protein Kinases><D-Glucose><Data><Dextrose><Diabetes Mellitus><Diameter><Disease><Disorder><Dysfunction><EFRAC><Ejection Fraction><Electrophysiology><Electrophysiology (science)><Extracellular Space><Functional disorder><Glucose><Goals><Heart failure><Hyperglycemia><Hypertension><Imaging Device><Imaging Instrument><Imaging Procedures><Imaging Technics><Imaging Techniques><Imaging Tool><Impairment><Intercellular Space><Intracellular Communication and Signaling><Ion Channel><Ionic Channels><Knowledge><Life Style><Lifestyle><Link><Measurement><Mediating><Membrane Channels><Metabolic><Mission><Modeling><Molecular><Muscle Cell Contraction><Muscle Contraction><Muscle function><Muscular Contraction><Myography><NIH><Nanoscopy><National Institutes of Health><Neurophysiology / Electrophysiology><Nucleotides><PKA><Pathologic><Pathway interactions><Physiologic><Physiological><Physiology><Physiopathology><Process><Property><Protein Kinase A><Proteins><Public Health><Risk><Role><Scaffolding Protein><Signal Transduction><Signal Transduction Systems><Signaling><Testing><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular Smooth Muscle><Vasomotor><Work><adenosine 3'5' monophosphate><arteriole><atherosclerotic coronary disease><base><bases><biological sensor><biological signal transduction><cAMP><cAMP-Dependent Protein Kinases><cardiac failure><coronary arterial disease><diabetes><diabetic><electrophysiological><experiment><experimental research><experimental study><experiments><extracellular><health goals><high blood pressure><hyperglycemic><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><in vivo><innovate><innovation><innovative><insight><live cell image><live cell imaging><live cellular image><live cellular imaging><member><model of animal><nanocomplexes><novel><particle><patch clamp><pathophysiology><pathway><preservation><pressure><response><social role><spatial and temporal><spatial temporal><spatiotemporal><therapeutic target><treatment strategy><vascular><vascular constriction><vasoconstriction>

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Madeline Nieves-Cintron

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$681,632

FY 2026

Project Title

Mechanisms of VSM dysfunction in diabetes and HFpEF

Grant Number:

5R01HL171014-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/15/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract . Vascular complications associated with lifestyle-related diseases, such as diabetes, contribute to an increased risk of hypertension, coronary artery disease, and heart failure associated with preserved ejection fraction (HFpEF). These vascular complications may involve, at least in part,...

Research Terms

<3'5'-cyclic ester of AMP><A kinase anchoring protein><AKAP><Address><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine Cyclic Monophosphate-Dependent Protein Kinases><Adenosine Triphosphate><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Adenylpyrophosphate><Animal Model><Animal Models and Related Studies><Animals><Arteries><Biochemistry><Biological Chemistry><Biosensor><Blood Glucose><Blood Pressure><Blood Sugar><Blood Vessels><Blood flow><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Complex><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Cyclic AMP><Cyclic AMP-Dependent Protein Kinases><D-Glucose><Data><Dextrose><Diabetes Mellitus><Diameter><Disease><Disorder><Dysfunction><EFRAC><Ejection Fraction><Electrophysiology><Electrophysiology (science)><Extracellular Space><Functional disorder><Glucose><Goals><Heart failure><Hyperglycemia><Hypertension><Imaging Device><Imaging Instrument><Imaging Procedures><Imaging Technics><Imaging Techniques><Imaging Tool><Impairment><Intercellular Space><Intracellular Communication and Signaling><Ion Channel><Ionic Channels><Knowledge><Life Style><Lifestyle><Link><Measurement><Mediating><Membrane Channels><Metabolic><Mission><Modeling><Molecular><Muscle Cell Contraction><Muscle Contraction><Muscle function><Muscular Contraction><Myography><NIH><Nanoscopy><National Institutes of Health><Neurophysiology / Electrophysiology><Nucleotides><PKA><Pathologic><Pathway interactions><Physiologic><Physiological><Physiology><Physiopathology><Process><Property><Protein Kinase A><Proteins><Public Health><Risk><Role><Scaffolding Protein><Signal Transduction><Signal Transduction Systems><Signaling><Testing><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular Smooth Muscle><Vasomotor><Work><adenosine 3'5' monophosphate><arteriole><atherosclerotic coronary disease><base><bases><biological sensor><biological signal transduction><cAMP><cAMP-Dependent Protein Kinases><cardiac failure><coronary arterial disease><diabetes><diabetic><electrophysiological><experiment><experimental research><experimental study><experiments><extracellular><health goals><high blood pressure><hyperglycemic><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><in vivo><innovate><innovation><innovative><insight><live cell image><live cell imaging><live cellular image><live cellular imaging><member><model of animal><nanocomplexes><novel><particle><patch clamp><pathophysiology><pathway><preservation><pressure><response><social role><spatial and temporal><spatial temporal><spatiotemporal><therapeutic target><treatment strategy><vascular><vascular constriction><vasoconstriction>

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Hai-Bin Ruan

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$676,905

FY 2026

Project Title

Stromal regulation of pathological bone remodeling

Grant Number:

1R01DK143274-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/16/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Bone disease is a major type of complication of diabetes. Fracture risk in patients with type 1 diabetes (T1D) and T2D can be six-fold and four-fold higher than those without diabetes. The impact of diabetes on bone health is becoming more evident because of the obesity epidemic and ...

Research Terms

<21+ years old><Ablation><Abscission><Acceleration><Adipocytes><Adipose Cell><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Age><Aging><Animals><Anorexia Nervosa><Anti-diabetic Agents><Anti-diabetic Drugs><Autoregulation><BM Stem Cell><BM derived progenitor><BM progenitor><BM- derived Stem Cells><Bioenergetics><Bone Diseases><Bone Formation><Bone Marrow><Bone Marrow Reticuloendothelial System><Bone Marrow Stem Cell><Bone Marrow progenitor><Bone Resorption><Bone Resorption Inhibition><Bone remodeling><Brittle Diabetes Mellitus><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Growth in Number><Cell Interaction><Cell Lineage><Cell Multiplication><Cell Proliferation><Cell Signaling><Cell-to-Cell Interaction><Cells><Cellular Metabolic Process><Cellular Proliferation><Complications of Diabetes Mellitus><Coupling><Cues><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diabetic mouse><Disease><Disorder><Drugs><Dysfunction><Endocrine Gland Secretion><Enzyme Gene><Enzymes><Estrogens><Excision><Extirpation><Fat Cells><Fats><Fatty acid glycerol esters><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Fracture><Functional disorder><Future><Genetic><Hematopoietic><Homeostasis><Hormonal><Hormones><HuB219><Humulin R><IDDM><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><In Vitro><Inflammation><Insulin><Insulin-Dependent Diabetes Mellitus><Intermediary Metabolism><Intervention><Intracellular Communication and Signaling><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><L-Serine><L-Threonine><LEP-R><LEPR Protein><Laboratories><Lead><Learning><Life><Life Style Modification><Link><Lipocytes><MGF Stem Cell Factor><Mast Cell Growth Factor><Mature Lipocyte><Mature fat cell><Maturity-Onset Diabetes Mellitus><Mediating><Medication><Menopause><Metabolic Processes><Metabolism><Mice><Mice Mammals><Minerals><Modeling><Modification><Molecular><Molecular Target><Murine><Mus><Myelogenous><Myeloid><Myelopoiesis><NIDDM><Nerve Degeneration><Neuron Degeneration><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nutritional><O-GlcNAc Transferase gene><O-GlcNAc transferase><O-GlcNAcase><OB Receptor><OB-R><Obesity Epidemic><Osteoblasts><Osteoclastic Bone Loss><Osteogenesis><Osteopathic><Osteopathic Medicine><Osteopathy><Osteoporosis><Osteoporotic risk><Outcome><PTH gene><Parathyrin><Parathyroid Hormone><Pathologic><Patients><Pb element><Persons><Pharmaceutical Preparations><Physiological Homeostasis><Physiology><Physiopathology><Population><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Pre-Clinical Model><Preclinical Models><Prevalence><Production><Proliferating><Protein Modification><Proteins><Proteomics><Receptor Gene><Regimen><Regular Insulin><Regulation><Removal><Research><Resolution><Risk><Role><STZ><Serine><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Steel Factor><Stem Cell Factor><Streptozocin><Streptozotocin><Sudden-Onset Diabetes Mellitus><Surgical Removal><Survey Instrument><Surveys><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Testing><Therapeutic><Therapeutic Estrogen><Therapeutic Hormone><Threonine><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Zanosar><adipogenesis><adult onset diabetes><adulthood><aged mice><aged mouse><ages><anti-diabetic><biological signal transduction><bone><bone disorder><bone fracture><bone fragility><bone health><bone loss><bone marrow derived progenitor><bone marrow derived stem cells><bone marrow stromal cell><bone marrow stromal stem cell><bone metabolism><bone quality><bone tissue formation><bone turnover><c-kit Ligand><cell metabolism><cellular metabaolism><co-morbid><co-morbidity><comorbidity><coping><customized therapy><customized treatment><density><diabetes><diabetes mouse model><diabetic><diabetic patient><dietary><drug/agent><effective therapy><effective treatment><elderly mice><flow cytophotometry><fracture risk><global gene expression><global transcription profile><glucose metabolism><heavy metal Pb><heavy metal lead><hemopoietic><hormonal regulation><hormonal signals><hormone regulation><hormone signals><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><insight><insulin dependent diabetes><insulin dependent type 1><insulin signaling><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><kit Ligand><leptin receptor><leptin-binding protein><lifestyle modification><lipid biosynthesis><lipogenesis><maturity onset diabetes><metabolic fitness><multipotency><multipotent><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neuronal degeneration><novel><nutritious><old mice><osteoclastogenesis><osteogenic><osteoporosis risk><overexpress><overexpression><parathormone><pathophysiology><patient specific therapies><patient specific treatment><peptide O-GlcNAc-beta-N-acetylglucosaminidase><peptide O-linked N-acetylglucosamine-beta-N-acetylglucosaminidase><perinatal development><pharmacologic><prevent><preventing><programs><resection><resolutions><response><risk developing osteoporosis><risk factor for osteoporosis><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><skeletal><social role><tailored medical treatment><tailored therapy><tailored treatment><therapeutic target><transcriptome><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><unique treatment>

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David Eric Arterburn

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$649,786

FY 2026

Project Title

Comparative Effectiveness and Safety of Metabolic/Bariatric Surgery, GLP-1, and SGLT-2 Medications for Patients with Obesity and Type 2 Diabetes

Grant Number:

5R01DK135515-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/6/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY More than 12 million Americans currently live with both obesity and type 2 diabetes (T2D), putting them in one of the highest risk groups for developing serious microvascular and macrovascular complications. The Ameri- can Diabetes Association’s clinical practice guidelines recommend...

Research Terms

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Rozalina Grubina McCoy

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$649,786

FY 2026

Project Title

Comparative Effectiveness and Safety of Metabolic/Bariatric Surgery, GLP-1, and SGLT-2 Medications for Patients with Obesity and Type 2 Diabetes

Grant Number:

5R01DK135515-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/6/2024

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY More than 12 million Americans currently live with both obesity and type 2 diabetes (T2D), putting them in one of the highest risk groups for developing serious microvascular and macrovascular complications. The Ameri- can Diabetes Association’s clinical practice guidelines recommend...

Research Terms

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RONALD A COHEN

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$628,834

FY 2026

Project Title

WISE II - Obesity and Type-2 Diabetes: Bariatric Surgery Effects on Brain Function

Grant Number:

5R01DK099334-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/25/2014

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The obesity epidemic is a major public health problem, contributing to various comorbid medical conditions, including diabetes, cardiovascular disease, and brain disturbances. The proposed project is designed to delineate mechanisms underlying the effects of severe obesity on brain health and cognit...

Research Terms

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Eric Porges

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$628,834

FY 2026

Project Title

WISE II - Obesity and Type-2 Diabetes: Bariatric Surgery Effects on Brain Function

Grant Number:

5R01DK099334-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/25/2014

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The obesity epidemic is a major public health problem, contributing to various comorbid medical conditions, including diabetes, cardiovascular disease, and brain disturbances. The proposed project is designed to delineate mechanisms underlying the effects of severe obesity on brain health and cognit...

Research Terms

View Full Project Details on NIH Reporter

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John B Williamson

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$628,834

FY 2026

Project Title

WISE II - Obesity and Type-2 Diabetes: Bariatric Surgery Effects on Brain Function

Grant Number:

5R01DK099334-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/25/2014

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The obesity epidemic is a major public health problem, contributing to various comorbid medical conditions, including diabetes, cardiovascular disease, and brain disturbances. The proposed project is designed to delineate mechanisms underlying the effects of severe obesity on brain health and cognit...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Konstantinos Drosatos

UNIVERSITY OF CINCINNATI, CINCINNATI, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$623,928

FY 2026

Project Title

Role of GLUT1 in diabetic cardiomyopathy

Grant Number:

5R01HL175251-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2025

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Diabetic cardiomyopathy (DbCM), which occurs in either Type-1 Diabetes (T1D) or Type-2 Diabetes (T2D), defines heart failure (HF) that occurs in the absence of coronary artery disease, hypertension, and valvular disease. Our research has discovered in human myocardial samples and mouse dia...

Research Terms

<2,4-thiazolidinedione><2-oxo-propanal><Ablation><Acetylformaldehyde><Address><Adult-Onset Diabetes Mellitus><Advanced Glycation End Products><Advanced Glycosylation End Products><Affect><Agonist><Anabolism><Atlases><Attenuated><Basal Transcription Factor><Basal transcription factor genes><Blood Glucose><Blood Sugar><Brittle Diabetes Mellitus><Cardiac><Cardiac Muscle Cells><Cardiac Myocytes><Cardiac Toxicity><Cardiocyte><Cardiotoxic><Cardiotoxicity><Cell Communication and Signaling><Cell Signaling><Clinical Research><Clinical Study><Co-Transporters><Complications of Diabetes Mellitus><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><D-Glucose><Data><Deacetylation><Death Rate><Development><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diabetic mouse><Dimethylbiguanidine><Dimethylguanylguanidine><Disease><Disorder><Drugs><Elements><Erythrocyte/Hepatoma Glucose Transporter><Event><Exclusion><FKHR><FOXO1><FOXO1A><FOXO1A gene><Fibrosis><Forkhead Box O1A><Forkhead in Rhabdomyosarcoma><GLP-1 receptor><GLP-I receptor><GLUT><GLUT 4 protein><GLUT1><GLUT4><GLUT4 gene><GLUT4 protein><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genetic><Genetic Transcription><Glitazones><Glucose><Glucose Binding Protein><Glucose Transport Protein><Glucose Transporter><Glucose Transporter 1><Heart><Heart Muscle Cells><Heart failure><Heart myocyte><Hexosamines><Human><Humulin R><Hyperglycemia><Hyperphagia><Hypertension><IDDM><Impairment><Insulin><Insulin Resistance><Insulin deficiency><Insulin-Dependent Diabetes Mellitus><Intracellular Communication and Signaling><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Kruppel-like transcription factors><Lead><Link><Maps><Maturity-Onset Diabetes Mellitus><Mediating><Medication><Metabolic><Metabolic Pathway><Metformin><Methylglyoxal><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Myocardial><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><Na element><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><O-GlcNAc Transferase gene><O-GlcNAc transferase><Overeating><Oxidative Stress><Pathologic><Pathway interactions><Patients><Pb element><Pharmaceutical Preparations><Population><Proteins><Proteome><Pyruvaldehyde><Pyruvic Aldehyde><RNA Expression><Regular Insulin><Research><Role><Route><SGLT 2 inhibitor><SGLT2i><SIRT1><SIRT1 gene><SLC2A1><SLC2A1 gene><Sampling><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Sirtuin 1><Slow-Onset Diabetes Mellitus><Sodium><Sodium glucose co-transporter 2 inhibitor><Solute Carrier Family 2, Facilitated Glucose Transporter, Member 1><Stable Diabetes Mellitus><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Therapeutic><Thiazolidinediones><Toxic effect><Toxicities><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Upregulation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><adult onset diabetes><advanced glycation endproduct><advanced glycosylation endproduct><atherosclerotic coronary disease><attenuate><attenuates><biological signal transduction><biosynthesis><cardiac failure><cardiac function><cardiomyocyte><cardioprotectant><cardioprotection><cardioprotective><coronary arterial disease><db/db mouse><developmental><diabetes><diabetes mouse model><diabetic><diabetic cardiomyopathy><diabetic cardiopathy><diabetic cardiopathy disease><diabetic cardiopathy disorder><diabetic cardiovascular disease><diabetic cardiovascular disorder><diabetic patient><drug/agent><function of the heart><global gene expression><global transcription profile><glucagon-like peptide-1 receptor><glucose uptake><heart function><heavy metal Pb><heavy metal lead><high blood pressure><hyperglycemic><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><in vivo><inhibitor><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin signaling><insulin tolerance><insulin-responsive glucose transporter><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lipidome><maturity onset diabetes><metabolome><metabonome><mitochondrial dysfunction><mortality rate><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><overexpress><overexpression><pathway><pharmacologic><polyphagia><prevent><preventing><social role><symporter><therapeutic target><thiazolidinedione><transcription factor><transcriptome><type 1 and type 2 diabetes><type 2 DM><type I and type II diabetes><type I diabetes><type II DM><type one diabetes><type two diabetes>

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Shan Luo

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$616,930

FY 2026

Project Title

Effects of Maternal Diabetes on early brain development

Grant Number:

5R01DK137899-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary One in every five youth are living with obesity, placing them at increased risk for developing diabetes and cardiovascular disease. Identifying risk factors contributing to obesity is extremely critical so that prevention strategies can be taken early to mitigate the obesity risk. Ma...

Research Terms

<0-11 years old><2 year old><2 years of age><3 year old><3 years of age><Accounting><Adolescent obesity><Affect><Ammon Horn><Area><Behavioral Mechanisms><Big Data><BigData><Biochemical Pathway><Birth><Body Weight><Brain><Brain Mapping><Brain Nervous System><Brain region><Cardiovascular Diseases><Causality><Child><Child Youth><Children (0-21)><Classification><Cohort Studies><Cornu Ammonis><Country><DWI (diffusion weighted imaging)><DWI-MRI><Data><Data Analyses><Data Analysis><Data Set><Development><Diabetes Mellitus><Diffusion><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Early Intervention><Economic Burden><Encephalon><Etiology><Exposure to><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Future><Generalized Growth><Genetic><Genomics><Gestation><Goals><Growth><Health Care Costs><Health Costs><Hippocampus><Hypothalamic structure><Hypothalamus><Image><Individual><Infant><Intervention><Knowledge><Length><Life><Link><Maps><Measures><Mechanisms of Behavior and Behavior Change><Meta-Analysis><Metabolic><Metabolic Networks><Modeling><Multimodal Imaging><NIH><National Institutes of Health><Neurosciences><Obesity><Overweight><Parturition><Pathway interactions><Perinatal Exposure><Population><Pregnancy><Pregnancy in Diabetes><Pregnancy in Diabetics><Preventative strategy><Prevention strategy><Preventive strategy><Public Health><Reproducibility><Research Resources><Resources><Rest><Rewards><Risk><Risk Factors><Site><Structure><Surface><Systematics><Techniques><Testing><Thick><Thickness><Tissue Growth><Treatment Efficacy><Uncertainty><United States National Institutes of Health><Work><Youth><Youth 10-21><adiposity><age 2><age 2 years><age 3><age 3 years><aged 2 years><aged two years><behavior mechanism><brain abnormalities><brain based><cardiovascular disorder><causation><child adiposity><child obesity><childhood adiposity><childhood obesity><cognitive control><cohort><cohort research study><cohort survey><computer based prediction><corpulence><critical period><dMRI><data analysis pipeline><data harmonization><data interpretation><data processing pipeline><deep learning based model><deep learning model><design><designing><developmental><diabetes><diffused><diffuses><diffusing><diffusion tensor imaging><diffusions><disease causation><doubt><early childhood><exposed in utero><fMRI><fetal exposure><harmonized data><health economics><high risk><hippocampal><hypothalamic><image-based method><imaging><imaging method><imaging modality><in utero exposure><infancy><infantile><innovate><innovation><innovative><insight><intervention efficacy><intra-uterine environmental exposure><intrauterine environmental exposure><kids><later in life><later life><machine learned algorithm><machine learning algorithm><machine learning based algorithm><maternal adiposity><maternal diabetes><maternal obesity><multi-modal imaging><multi-modal neuro-imaging><multi-modality><multi-modality imaging><multimodal neuroimaging><multimodality><multimodality imaging><neonate><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><obese adolescents><obese children><obesity among adolescents><obesity development><obesity during adolescence><obesity during childhood><obesity in adolescence><obesity in adolescents><obesity in children><obesity risk><offspring><offspring obesity><ontogeny><pathway><pediatric obesity><predictive biological marker><predictive biomarkers><predictive marker><predictive modeling><predictive molecular biomarker><predictive signature><prenatal exposure><prenatally exposed><prepregnancy obesity><risk for obesity><risk of obesity><socio-economic><socio-economically><socioeconomically><socioeconomics><therapeutic efficacy><therapy efficacy><three year old><three years of age><two year old><two years of age><youngster><youth adiposity><youth age>

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Sae Takada

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$616,107

FY 2026

Project Title

Intersectional analysis of the Whole Person Care-Los Angeles social care intervention on diabetes quality of care, glycemic control, complications, and healthcare utilization

Grant Number:

1R01DK146058-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract In the U.S., sex, race, and ethnicity are associated with differences in diabetes prevalence, quality of care, glycemic control, and complications. These differeneces have been partially attributed to differences in adverse social determinants of health (SDOH) between the groups, such as l...

Research Terms

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Teresa Janevic

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$609,246

FY 2026

Project Title

Policy levers to reduce diabetes after gestational diabetes

Grant Number:

5R01DK134725-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/9/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Updated project title: Policy levers to reduce diabetes after gestational diabetes Project Summary Gestational diabetes (GDM) is a common complication of pregnancy with substantial racial-ethnic differences. These racial-ethnic differences in GDM have profound implications for life course risk of ty...

Research Terms

<Adult-Onset Diabetes Mellitus><Asian Females><Asian Women><Birth Certificates><Black><Black race><Cardiovascular Diseases><Caucasian Females><Caucasian Women><Cell Communication and Signaling><Cell Signaling><Complex><Cost Effectiveness Analysis><Data><Data Bases><Data Linkages><Databases><Development><Diabetes Mellitus><Diabetes prevention><Diagnosis><Diet><Disparities><Disparity><Disproportionate number of females><Disproportionate number of women><Disproportionately affects females><Disproportionately affects women><Disproportionately impacts females><Disproportionately impacts women><Disproportionately in females><Disproportionately in women><East Asian><Economics><Environment><Equity><Ethnic Group><Ethnic Origin><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity><Ethnicity People><Ethnicity Population><Face><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Green space><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health system><Hemoglobin A(1)><High Risk Woman><Hispanic Females><Hispanic Women><Immigrant><Incidence><Individual><Intervention><Interview><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Latina><Latina Population><Latina females><Latina women><Latina/e women><Latina/x women><Latinas><Latine females><Latine women><Latino females><Latino women><Latinx females><Latinx women><Life Cycle><Life Cycle Stages><Literature><Lived experience><Lived experiences><Maps><Maturity-Onset Diabetes Mellitus><Measures><Mental Health><Mental Hygiene><Methods><Modeling><NIDDM><Neighborhoods><New York City><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Patients><Physical activity><Physiologic><Physiological><Policies><Policy Maker><Post-partum Women><Postpartum Period><Postpartum Women><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Pregnancy><Pregnancy Complications><Pregnancy-Induced Diabetes><Prevention><Psychological Health><Race><Races><Record Linkage Study><Registries><Research><Research Design><Research Priority><Research Resources><Resources><Retrospective cohort><Risk><Risk Factors><Science><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Social Environment><South Asian><Stable Diabetes Mellitus><Study Type><Subgroup><System><T2 DM><T2D><T2DM><Targeted Research><Testing><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Update><White Females><White Women><Woman><adult onset diabetes><after gestational diabetes><at-risk females><at-risk women><barrier to care><barrier to health care><barrier to treatment><biological signal transduction><black female><black women><built environment><cardiometabolic risk><cardiovascular disorder><cohort><complications during pregnancy><cost><cost effective><cost efficient analysis><cost-effective analysis><cumulative risk><data base><data registry><deprivation><developmental><diabetes><diabetes risk><diets><differences due to race><differences in race><differs by race><differs in race><disparities in race><disparity due to race><disparity in ethnic><economic><ethnic based disparity><ethnic difference><ethnic disadvantage><ethnic disparity><ethnic inequality><ethnic inequity><ethnic subgroup><ethnicity difference><ethnicity disparity><ethnicity group><experience><faces><facial><female bias><female predominance><female preponderance><females at high risk><following gestational diabetes><food environment><gestational diabetes history><greenspace><hemoglobin A1c><high risk females><improved><inequality due to race><inequity due to race><innovate><innovation><innovative><ketosis resistant diabetes><life course><maturity onset diabetes><multi-ethnic><multiethnic><novel><obstacle to care><obstacle to health care><population based><post-partum><pre-diabetes><pre-diabetic><prediabetic><predominance in females><predominance in women><pregnancy diabetes><pregnancy-related complications><prevent><preventing><protective factors><race based differences><race based disparity><race based inequality><race based inequity><race differences><race disparity><race related differences><race related disparity><race related inequality><race related inequity><racial><racial background><racial difference><racial disparity><racial inequality><racial inequity><racial origin><racially different><racially unequal><social><social climate><social cohesion><social context><socioenvironment><socioenvironmental><study design><type 2 DM><type II DM><type two diabetes><women at high risk><women of color><women's predominance><women's preponderance>

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Petter Bjornstad

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$599,983

FY 2026

Project Title

Pathogenesis of kidney disease in type 1 diabetes: a modern kidney biopsy cohort

Grant Number:

5R01DK132399-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/23/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract This project will build a new kidney biopsy cohort to characterize the molecular, morphometric, and metabolic features of diabetic kidney disease (DKD) over the modern clinical course of type 1 diabetes (T1D). Landmark kidney biopsy studies have enhanced our understanding of...

Research Terms

<21+ years old><AMP Kinase><ATP-AMP Phosphotransferase><ATP-AMP Transphosphorylase><Active Follow-up><Adenylokinase><Adult><Adult Human><Albuminuria><Biopsy><Blood Plasma><Body Tissues><Brittle Diabetes Mellitus><Cell Communication and Signaling><Cell Signaling><Cellular injury><Cessation of life><Clampings><Clinical><Closure by clamp><Complex><Continuous Glucose Monitor><Cross Sectional Analysis><DEXA><DXA><Data><Data Banks><Databanks><Death><Development><Diabetic Kidney Disease><Diabetic Nephropathy><Dialysis><Dialysis procedure><Disease Outcome><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Energy Expenditure><Energy Metabolism><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Exhibits><FK506 Binding Protein 12-Rapamycin Associated Protein 1><FKBP12 Rapamycin Complex Associated Protein 1><FRAP1><FRAP1 gene><FRAP2><Gene Transcription><Genetic Transcription><Glomerular Filtration Rate><Glucose Clamp><Goals><HIF 1 alpha><HIF-1alpha><HIF1-Alpha><HIF1A><HIF1A gene><HIF1α><Humulin R><Hyperglycemia><Hyperinsulinemic Clamp><Hypoxia><Hypoxia Inducible Factor><Hypoxic><IDDM><Impairment><Incidence><Individual><Inflammation><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Intermediary Metabolism><Intra-abdominal><Intracellular Communication and Signaling><Iohexol><Iohexol 350><Juvenile-Onset Diabetes Mellitus><K ATPase><Ketosis-Prone Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Grafting><Kidney Insufficiency><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Knowledge><Lesion><Living Donors><MOP1><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measurement><Measures><Mechanistic Target of Rapamycin><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Metabolic Pathway><Metabolic Processes><Metabolism><Methods><Mitochondria><Modernization><Molecular><Molecular Fingerprinting><Molecular Profiling><Myokinase><NMR Imaging><NMR Tomography><Na element><Nephropathy><Noise><Novolin R><Nuclear Magnetic Resonance Imaging><O element><O2 element><Obesity><Oxygen><Oxygen Deficiency><Participant><Pathogenesis><Pathologic><Performance><Persons><Plasma><Plasma Serum><Publishing><RAFT1><RNA Expression><Regular Insulin><Renal Disease><Renal Failure><Renal Grafting><Renal Insufficiency><Renal Plasma Flow><Renal Transplantation><Renal Transplants><Residual><Residual state><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Role><Signal Transduction><Signal Transduction Systems><Signaling><Sodium><Structure><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><Testing><Tissues><Transcription><Tubular><Tubular formation><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Upregulation><Urine><Work><Youth><Youth 10-21><Zeugmatography><abdominal adiposity><abdominal fat><absorption><active followup><adenylate kinase><adiposity><adulthood><biological signal transduction><cardiovascular disease risk><cardiovascular disorder risk><cell damage><cell injury><cellular damage><clinical phenotype><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><damage to cells><data depository><data repository><data set repository><dataset repository><developmental><diabetes management><diabetes mellitus management><diabetic management><dialysis therapy><disease prevention><disorder prevention><effective therapy><effective treatment><follow up><follow-up><followed up><followup><glycemic control><hyperglycemic><improved><injury to cells><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin sensitivity><insulin tolerance><interstitial><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kidney biopsy><kidney disorder><kidney hypoxia><kidney tx><live kidney donor><living kidney donor><mTOR><malleable risk><mammalian target of rapamycin><metabolic phenotype><metabolism measurement><metabolomics><metabonomics><metabotype><mitochondrial><mitochondrial dysfunction><modifiable risk><molecular profile><molecular signature><novel><potassium ATPase><precision medicine><precision-based medicine><premature><prematurity><prevent><preventing><renal><renal biopsy><renal disorder><renal hypoxia><resolutions><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><stem><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><transcriptomics><type I diabetes><type one diabetes><youth age>

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Ian H de Boer

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$599,983

FY 2026

Project Title

Pathogenesis of kidney disease in type 1 diabetes: a modern kidney biopsy cohort

Grant Number:

5R01DK132399-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/23/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract This project will build a new kidney biopsy cohort to characterize the molecular, morphometric, and metabolic features of diabetic kidney disease (DKD) over the modern clinical course of type 1 diabetes (T1D). Landmark kidney biopsy studies have enhanced our understanding of...

Research Terms

<21+ years old><AMP Kinase><ATP-AMP Phosphotransferase><ATP-AMP Transphosphorylase><Active Follow-up><Adenylokinase><Adult><Adult Human><Albuminuria><Biopsy><Blood Plasma><Body Tissues><Brittle Diabetes Mellitus><Cell Communication and Signaling><Cell Signaling><Cellular injury><Cessation of life><Clampings><Clinical><Closure by clamp><Complex><Continuous Glucose Monitor><Cross Sectional Analysis><DEXA><DXA><Data><Data Banks><Databanks><Death><Development><Diabetic Kidney Disease><Diabetic Nephropathy><Dialysis><Dialysis procedure><Disease Outcome><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Energy Expenditure><Energy Metabolism><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Exhibits><FK506 Binding Protein 12-Rapamycin Associated Protein 1><FKBP12 Rapamycin Complex Associated Protein 1><FRAP1><FRAP1 gene><FRAP2><Gene Transcription><Genetic Transcription><Glomerular Filtration Rate><Glucose Clamp><Goals><HIF 1 alpha><HIF-1alpha><HIF1-Alpha><HIF1A><HIF1A gene><HIF1α><Humulin R><Hyperglycemia><Hyperinsulinemic Clamp><Hypoxia><Hypoxia Inducible Factor><Hypoxic><IDDM><Impairment><Incidence><Individual><Inflammation><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Intermediary Metabolism><Intra-abdominal><Intracellular Communication and Signaling><Iohexol><Iohexol 350><Juvenile-Onset Diabetes Mellitus><K ATPase><Ketosis-Prone Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Grafting><Kidney Insufficiency><Kidney Transplantation><Kidney Transplants><Kidney Urinary System><Knowledge><Lesion><Living Donors><MOP1><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measurement><Measures><Mechanistic Target of Rapamycin><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Metabolic Pathway><Metabolic Processes><Metabolism><Methods><Mitochondria><Modernization><Molecular><Molecular Fingerprinting><Molecular Profiling><Myokinase><NMR Imaging><NMR Tomography><Na element><Nephropathy><Noise><Novolin R><Nuclear Magnetic Resonance Imaging><O element><O2 element><Obesity><Oxygen><Oxygen Deficiency><Participant><Pathogenesis><Pathologic><Performance><Persons><Plasma><Plasma Serum><Publishing><RAFT1><RNA Expression><Regular Insulin><Renal Disease><Renal Failure><Renal Grafting><Renal Insufficiency><Renal Plasma Flow><Renal Transplantation><Renal Transplants><Residual><Residual state><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Role><Signal Transduction><Signal Transduction Systems><Signaling><Sodium><Structure><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><Testing><Tissues><Transcription><Tubular><Tubular formation><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Upregulation><Urine><Work><Youth><Youth 10-21><Zeugmatography><abdominal adiposity><abdominal fat><absorption><active followup><adenylate kinase><adiposity><adulthood><biological signal transduction><cardiovascular disease risk><cardiovascular disorder risk><cell damage><cell injury><cellular damage><clinical phenotype><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><damage to cells><data depository><data repository><data set repository><dataset repository><developmental><diabetes management><diabetes mellitus management><diabetic management><dialysis therapy><disease prevention><disorder prevention><effective therapy><effective treatment><follow up><follow-up><followed up><followup><glycemic control><hyperglycemic><improved><injury to cells><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin sensitivity><insulin tolerance><interstitial><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kidney biopsy><kidney disorder><kidney hypoxia><kidney tx><live kidney donor><living kidney donor><mTOR><malleable risk><mammalian target of rapamycin><metabolic phenotype><metabolism measurement><metabolomics><metabonomics><metabotype><mitochondrial><mitochondrial dysfunction><modifiable risk><molecular profile><molecular signature><novel><potassium ATPase><precision medicine><precision-based medicine><premature><prematurity><prevent><preventing><renal><renal biopsy><renal disorder><renal hypoxia><resolutions><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><stem><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><transcriptomics><type I diabetes><type one diabetes><youth age>

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DEBORAH A. ELLIS

WAYNE STATE UNIVERSITY, DETROIT, MI

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$592,721

FY 2026

Project Title

Family mHealth Intervention to Improve Health Outcomes in Black Youth with Type 1 Diabetes: A Multi-Center Randomized Controlled Trial

Grant Number:

5R01MD018583-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Black adolescents with type 1 diabetes (T1D) face disparities in diabetes-related health outcomes such as higher risk for suboptimal glycemic control, which can lead to diabetes complications. Given the critical protective role played by families in the health of adolescents with T1D, family-based i...

Research Terms

<12-20 years old><15 year old><15 years of age><Active Follow-up><Adolescence><Adolescent><Adolescent Youth><Affect><Anxiety><Area><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Black><Black race><Blood Glucose><Blood Sugar><Brittle Diabetes Mellitus><Care Givers><Caregivers><Caring><Child Rearing><Clinic><Clinic Visits><Clinical Trials><Collaborations><Complications of Diabetes Mellitus><Computer software><Conditioning Therapy><Conflict><Conflict (Psychology)><Cost Analyses><Cost Analysis><Decrease disparity><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Disparities><Disparity><Distress><Dose><Equity><Evaluation><Face><Family><Family Health><Family Relations><Family Relationship><Family health status><Family member><Health><Health Care><Health Care Technology><Health Technology><History><Hospital Admission><Hospitalization><IDDM><Individual><Insulin-Dependent Diabetes Mellitus><Intervention><Intervention Trial><Interventional trial><Interview><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Literature><Lower disparity><Mental Depression><Mental Health><Mental Hygiene><Modeling><Motivation><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><Outcome><Parenting><Parenting behavior><Parents><Personal Satisfaction><Phase><Play><Psychological Health><Randomized, Controlled Trials><Recording of previous events><Reporting><Research><Research Support><Risk><Risk Factors><Role><Sampling><Software><Stress><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Tablet Computer><Testing><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Vulnerable Populations><Work><Youth><Youth 10-21><active followup><adolescence (12-20)><adolescent health><age 15><age 15 years><assess cost><attentional control><behavior change><behavior intervention><behavior test><behavioral health><behavioral health intervention><behavioral intervention><behavioral test><childrearing><clinical research site><clinical site><community advisory board><community advisory committee><community advisory panel><cost assessment><cost effectiveness><cost evaluation><depression><design><designing><determine efficacy><developmental><diabetes><diabetes distress><diabetes management><diabetes mellitus management><diabetes-related distress><diabetes-specific distress><diabetic management><disparity in health><disparity reduction><distress related to diabetes><distress specific to diabetes><e-Health><eHealth><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><electronic health><evaluate cost><evaluate efficacy><examine cost><examine efficacy><experience><faces><facial><fifteen year old><fifteen years of age><follow up><follow-up><followed up><followup><glycemic control><health disparity><high risk><histories><iPad><improved><independent self care><insulin dependent diabetes><insulin dependent type 1><intervention cost><intervention design><intervention refinement><juvenile><juvenile diabetes><juvenile diabetes mellitus><juvenile human><ketosis prone diabetes><m-Health><mHealth><mHealth therapeutic><mHealth therapy><mHealth treatment><mhealth interventions><mitigate disparity><mobile health><mobile health intervention><mobile health therapeutic><mobile health therapy><mobile health treatment><parent><parent monitoring><parental monitoring><poor health outcome><primary care giver><primary caregiver><primary end point><primary endpoint><protective factors><randomized control trial><randomized, clinical trials><recruit><reduce disparity><reduced health outcome><reduction in disparity><resilience><resilient><secondary end point><secondary endpoint><social role><tablet device><therapy design><treatment design><type I diabetes><type one diabetes><vulnerable group><vulnerable individual><vulnerable people><well-being><wellbeing><worse health outcome><youth age>

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Katherine Diaz Vickery

HENNEPIN HEALTHCARE RESEARCH INSTITUTE, MINNEAPOLIS, MN

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$591,045

FY 2026

Project Title

Effectiveness of the Diabetes Homeless Medication Support (D-HOMES) program on diabetes management

Grant Number:

5R01DK139152-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Among the millions of Americans who experience homelessness yearly, thousands die prematurely from diabetes. They do so at a rate that is 3 to 6 times higher than the general population. The federal definitions of homelessness include people staying in shelters or subsidized housing, sleeping outsid...

Research Terms

<21+ years old><Address><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><American><American Indian><Area><Assess implementation><Automobile Driving><Behavioral><Behavioral Model><Black><Black race><Blood Glucose><Blood Pressure><Blood Sugar><Chronic><Complications of Diabetes Mellitus><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Drug Prescribing><Drug Prescriptions><Drugs><Education><Educational aspects><Effectiveness><Emotional well being><Ethnic Origin><Ethnicity><Evaluation><Evidence based practice><Feels well><Food><Funding><Future><General Population><General Public><Generalized Growth><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Growth><HRSA><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Health Resources and Services Administration><Health behavior><Hemoglobin><Hemoglobin A(1)><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Homelessness><Hospital Admission><Hospitalization><Housing><Implementation assessment><Individual><Ketosis-Resistant Diabetes Mellitus><Latino Population><Latino group><Latino individual><Latino people><Latinos><Level of Evidence><Literature><Lived experience><Lived experiences><Low Income Population><Low income group><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Maturity-Onset Diabetes Mellitus><Medication><Methods><Modeling><Morbidity><Motivation><NIDDM><Names><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal mental condition><Normal mental state><Normal psyche><Outcome><Participant><Patient Self-Report><Persons><Pharmaceutical Preparations><Population><Prevalence><Provider><Psychological Well Being><Public Health><RE-AIM><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Recommendation><Reporting><Research><Research Resources><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Resources><Risk><Safety><Self-Report><Sense of well-being><Shelter facility><Site><Sleep><Slow-Onset Diabetes Mellitus><Spanish/English><Stable Diabetes Mellitus><Survey Instrument><Surveys><T2 DM><T2D><T2DM><Time><Tissue Growth><Training><Treatment Effectiveness><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States Health Resources and Services Administration><Well in self><Work><access to medications><adult onset diabetes><adulthood><behavioral health><care as usual><develop therapy><diabetes><diabetes distress><diabetes education><diabetes management><diabetes mellitus management><diabetes self-care><diabetes self-management><diabetes-related distress><diabetes-specific distress><diabetic management><distress related to diabetes><distress specific to diabetes><driving><drug adherence><drug compliance><drug/agent><effectiveness and implementation trial><effectiveness measure><effectiveness testing><effectiveness-implementation randomized trial><effectiveness/implementation hybrid><effectiveness/implementation hybrid trial><effectiveness/implementation trial><emotional wellbeing><emotional wellness><evaluate implementation><evaluation of implementation><evidence base><experience><glycemic control><health related behavior><hemoglobin A1c><homeless><houselessness><implementation evaluation><improved><intervention development><ketosis resistant diabetes><low income individual><low income people><maturity onset diabetes><medication access><medication adherence><medication compliance><medication prescription><mental well-being><mental wellbeing><mental wellness><mortality><name><named><naming><ontogeny><peer><pilot test><premature><prematurity><prescribed medication><primary outcome><programs><psychologic><psychological><psychological distress><psychological wellbeing><psychological wellness><racial disparities in health><racial health disparity><reach, efficacy, adoption, implementation, and maintenance><satisfaction><secondary outcome><self wellness><sense of wellbeing><shelter><shelter housing><shelters><social><supported housing><supportive housing><therapy development><treatment as usual><treatment development><type 2 DM><type II DM><type two diabetes><unhoused><usual care>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yu-Long Li

UNIVERSITY OF NEBRASKA MEDICAL CENTER, OMAHA, NE

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$573,159

FY 2026

Project Title

Potential mechanism underlying parasympathetic neuronal dysfunction in diabetes

Grant Number:

5R01HL168500-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2024

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Diabetes-induced imbalance of autonomic efferent neuronal tone (reduced parasympathetic activity and increased sympathetic activity) is involved in sudden cardiac death and is responsible for high mortality in diabetic patients. Increasing cardiovascular vagal tone significantly redu...

Research Terms

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Nicolai Doliba

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$544,201

FY 2026

Project Title

Role of Alpha Cells in Pathogenesis of Type 1 Diabetes

Grant Number:

5R01DK136564-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Longitudinal studies have shown that individuals at high genetic risk for type 1 diabetes (T1D) progress through several distinct stages prior to the onset of clinical symptoms. Although the factors causally involved in the rate of progression are poorly understood, the presence of i...

Research Terms

<3'5'-cyclic ester of AMP><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine Cyclic Monophosphate-Dependent Protein Kinases><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Affect><Alpha Cell><Antidiabetic Hormone><Assay><Autoantibodies><B9 endocrine pancreas><Beta Cell><Bioassay><Bioenergetics><Biological Assay><Biological Markers><Biosensor><Brittle Diabetes Mellitus><Cell Aggregation><Cell Body><Cell Communication and Signaling><Cell Function><Cell Membrane Permeability><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Clinical><Complex><Concentration Camps><Custom><Cyclic AMP><Cyclic AMP-Dependent Protein Kinases><D-Glucose><Data><Defect><Development><Dextrose><Diabetes Mellitus><Disease><Disorder><Down-Regulation><Drugs><Dysfunction><Electrophysiology><Electrophysiology (science)><Endocrine Pancreas><Evaluation><Exocytosis><Functional disorder><Future><Genes><Genetic><Genetic Risk><Glucagon><Glucagon Cell><Glucagon Secreting Cell><Glucokinase><Glucose><Glukagon><Glutamate Carboxy-Lyase><Glutamate Decarboxylase><Glutamic Acid Decarboxylase><Glycolysis><HG-Factor><Human><Hyperglycemia><Hyperglycemic-Glycogenolytic Factor><IDDM><Immune response><Impairment><Individual><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Intracellular Communication and Signaling><Ion Channel><Ionic Channels><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><L-Glutamate-1-carboxy-lyase><Longitudinal Studies><Longitudinal Surveys><Measurement><Measures><Medication><Membrane Channels><Membrane Potentials><Mitochondria><Modern Man><Modification><Nesidioblasts><Neurophysiology / Electrophysiology><Outcomes Research><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><PKA><PKA inhibitor><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Pathway interactions><Pharmaceutical Preparations><Phenotype><Physiopathology><Position><Positioning Attribute><Property><Protein Kinase A><Resting Potentials><Role><Signal Transduction><Signal Transduction Systems><Signaling><Spirometry><Subcellular Process><Sudden-Onset Diabetes Mellitus><Symptoms><T1 DM><T1 diabetes><T1D><T1DM><Testing><Transmembrane Potentials><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Viral><adenosine 3'5' monophosphate><alpha-cell><analog><arm><autoimmune antibody><autoreactive antibody><bio-markers><biologic marker><biological sensor><biological signal transduction><biomarker><cAMP><cAMP-Dependent Protein Kinases><customs><developmental><diabetes><drug/agent><electrophysiological><experiment><experimental research><experimental study><experiments><glucose metabolism><host response><hyperglycemic><immune system response><immunoresponse><insulin dependent diabetes><insulin dependent type 1><insulin secretion><islet><islet autoantibody><islet cell antibody><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><lens><lenses><long-term study><longitudinal outcome studies><longitudinal research study><membrane permeability><mitochondrial><multidisciplinary><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><non-diabetic><nondiabetic><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathophysiology><pathway><pharmacologic><prevent><preventing><protein kinase inhibitor><ratiometric><self reactive antibody><social role><transcriptomics><type I diabetes><type one diabetes><α-cell><β-cell><β-cells><βCell>

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DORIS A STOFFERS

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$544,201

FY 2026

Project Title

Role of Alpha Cells in Pathogenesis of Type 1 Diabetes

Grant Number:

5R01DK136564-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Longitudinal studies have shown that individuals at high genetic risk for type 1 diabetes (T1D) progress through several distinct stages prior to the onset of clinical symptoms. Although the factors causally involved in the rate of progression are poorly understood, the presence of i...

Research Terms

<3'5'-cyclic ester of AMP><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine Cyclic Monophosphate-Dependent Protein Kinases><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Affect><Alpha Cell><Antidiabetic Hormone><Assay><Autoantibodies><B9 endocrine pancreas><Beta Cell><Bioassay><Bioenergetics><Biological Assay><Biological Markers><Biosensor><Brittle Diabetes Mellitus><Cell Aggregation><Cell Body><Cell Communication and Signaling><Cell Function><Cell Membrane Permeability><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Clinical><Complex><Concentration Camps><Custom><Cyclic AMP><Cyclic AMP-Dependent Protein Kinases><D-Glucose><Data><Defect><Development><Dextrose><Diabetes Mellitus><Disease><Disorder><Down-Regulation><Drugs><Dysfunction><Electrophysiology><Electrophysiology (science)><Endocrine Pancreas><Evaluation><Exocytosis><Functional disorder><Future><Genes><Genetic><Genetic Risk><Glucagon><Glucagon Cell><Glucagon Secreting Cell><Glucokinase><Glucose><Glukagon><Glutamate Carboxy-Lyase><Glutamate Decarboxylase><Glutamic Acid Decarboxylase><Glycolysis><HG-Factor><Human><Hyperglycemia><Hyperglycemic-Glycogenolytic Factor><IDDM><Immune response><Impairment><Individual><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Intracellular Communication and Signaling><Ion Channel><Ionic Channels><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><L-Glutamate-1-carboxy-lyase><Longitudinal Studies><Longitudinal Surveys><Measurement><Measures><Medication><Membrane Channels><Membrane Potentials><Mitochondria><Modern Man><Modification><Nesidioblasts><Neurophysiology / Electrophysiology><Outcomes Research><Oxidative Phosphorylation><Oxidative Phosphorylation Pathway><PKA><PKA inhibitor><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Pathway interactions><Pharmaceutical Preparations><Phenotype><Physiopathology><Position><Positioning Attribute><Property><Protein Kinase A><Resting Potentials><Role><Signal Transduction><Signal Transduction Systems><Signaling><Spirometry><Subcellular Process><Sudden-Onset Diabetes Mellitus><Symptoms><T1 DM><T1 diabetes><T1D><T1DM><Testing><Transmembrane Potentials><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Viral><adenosine 3'5' monophosphate><alpha-cell><analog><arm><autoimmune antibody><autoreactive antibody><bio-markers><biologic marker><biological sensor><biological signal transduction><biomarker><cAMP><cAMP-Dependent Protein Kinases><customs><developmental><diabetes><drug/agent><electrophysiological><experiment><experimental research><experimental study><experiments><glucose metabolism><host response><hyperglycemic><immune system response><immunoresponse><insulin dependent diabetes><insulin dependent type 1><insulin secretion><islet><islet autoantibody><islet cell antibody><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><lens><lenses><long-term study><longitudinal outcome studies><longitudinal research study><membrane permeability><mitochondrial><multidisciplinary><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><non-diabetic><nondiabetic><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathophysiology><pathway><pharmacologic><prevent><preventing><protein kinase inhibitor><ratiometric><self reactive antibody><social role><transcriptomics><type I diabetes><type one diabetes><α-cell><β-cell><β-cells><βCell>

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Yun Sok Lee

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$535,666

FY 2026

Project Title

Coronary Endothelial Cell Dysfunction in Diabetes: Role of MFGE8

Grant Number:

5R01HL142214-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2018

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Program Summary/Abstract Diabetes is a global epidemic. Many patients with diabetes suffer from and die of heart disease or stroke. Diabetic heart diseases include diabetic cardiomyopathy, obstructive coronary artery disease (CAD), and coronary microvascular disease (CMD, also known as non-obstructi...

Research Terms

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Ayako Makino

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$535,666

FY 2026

Project Title

Coronary Endothelial Cell Dysfunction in Diabetes: Role of MFGE8

Grant Number:

5R01HL142214-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2018

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Program Summary/Abstract Diabetes is a global epidemic. Many patients with diabetes suffer from and die of heart disease or stroke. Diabetic heart diseases include diabetic cardiomyopathy, obstructive coronary artery disease (CAD), and coronary microvascular disease (CMD, also known as non-obstructi...

Research Terms

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Vijay Karkal Hegde

TEXAS TECH UNIVERSITY, LUBBOCK, TX

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$533,727

FY 2026

Project Title

Serotonin modulated mitochondrial dysfunction in Depression Diabetes and Dementia (3Ds)

Grant Number:

5R01AG071560-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2022

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Our research aims to understand the role of serotonin modulated mitochondrial biogenesis in diabetes, depression, and dementia (Alzheimer's disease, AD). Diabetes and depression are independent risk factors for dementia and worsen the dementia pathology and therapeutic response. Dep...

Research Terms

<5-HT><5-Hydroxytryptamine><5HT><AD dementia><AD patients><Adult-Onset Diabetes Mellitus><Age Months><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's disease patient><Alzheimer's patient><Alzheimers Dementia><Amentia><Ammon Horn><Area><Autophagocytosis><Autoregulation><Behavioral Symptoms><Biogenesis><Biological><Body Tissues><Brain><Brain Nervous System><Brain Stem><Brainstem><CNS Nervous System><Cardiovascular Diseases><Cause of Death><Cell Body><Cell model><Cells><Cellular model><Central Nervous System><Cessation of life><Chronic><Chronic Disease><Chronic Illness><Circadian Rhythms><Citalopram><Clinical><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complementary DNA><Complex><Cornu Ammonis><Cytalopram><D-Glucose><Data><Death><Defect><Dementia><Dextrose><Diabetes Mellitus><Diabetic mouse><Disease><Disease Progression><Disorder><Disturbance in cognition><Dorsal><Dose><Drug Prescribing><Drug Prescriptions><Dysfunction><Encephalon><Energy Expenditure><Energy Metabolism><Enteramine><Exposure to><Functional disorder><Gene Transcription><Genetic Transcription><Glucose><Goals><Hippocampus><Hippophaine><Histones><Homeostasis><Hyperglycemia><Hypothalamic structure><Hypothalamus><Impaired cognition><Impairment><In Vitro><Inflammation><Insulin Resistance><Investigators><Ketosis-Resistant Diabetes Mellitus><Link><MT-bound tau><Maturity-Onset Diabetes Mellitus><Mental Depression><Metabolic><Mice><Mice Mammals><Mitochondria><Modeling><Molecular><Murine><Mus><NIDDM><Nerve Cells><Nerve Degeneration><Nerve Transmitter Substances><Nerve Unit><Nervous System Physiology><Neural Cell><Neural Transmission><Neuraxis><Neurocyte><Neurologic function><Neurological function><Neuron Degeneration><Neurons><Neurotransmitters><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nyctohemeral Rhythm><Obesity><Origin of Life><Outcome><Outcomes Research><Oxidative Stress><Pathogenesis><Pathology><Pathway interactions><Peripheral Nervous System><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Play><Population><Preventive><Primary Senile Degenerative Dementia><Process><Qualifying><RNA Expression><Reporting><Research><Research Design><Research Personnel><Research Subjects><Researchers><Risk Factors><Rodent><Rodentia><Rodents Mammals><Role><SSRI><SSRIs><Selective Serotonin Reuptake Inhibitor><Selective serotonin re-uptake inhibitor><Serotonin><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Study Type><Synapses><Synaptic><Synaptic Transmission><T2 DM><T2D><T2DM><TPH2><Testing><Time><Tissues><Transcription><Transfection><Transgenic Mice><Transgenic Model><Twenty-Four Hour Rhythm><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><aberrant tau><aberrant tau protein><abnormal tau><abnormal tau protein><adiposity><adult onset diabetes><autophagy><biologic><cDNA><cardiovascular disorder><cell resilience><cell resiliency><cellular resilience><cellular resiliency><chronic disorder><circadian process><circadian rhythmicity><co-morbid><co-morbid depression><co-morbid with depression><co-morbidity><co-morbidity with depression><cognitive dysfunction><cognitive loss><comorbid depression><comorbid with depression><comorbidity><comorbidity with depression><corpulence><daily biorhythm><dementia risk><depression><depression co-morbidity><depression comorbidity><diabetes><diabetes mouse model><diabetic><experiment><experimental research><experimental study><experiments><hippocampal><hyperglycemic><hypothalamic><improved><in vitro Model><in vivo><in vivo Model><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><medication prescription><microtubule associated protein tau mutation><microtubule bound tau><microtubule-associated protein tau mutation><microtubule-bound tau><mitochondrial><mitochondrial dysfunction><mouse model><murine model><mutant><mutant tau><mutant tau protein><mutation in microtubule associated protein tau><mutation in microtubule-associated protein tau><nervous system function><neural degeneration><neurodegeneration><neurodegenerative><neurogenesis><neurological degeneration><neuronal><neuronal degeneration><neuroprotection><neuroprotective><pathogenic tau><pathogenic tau gene mutation><pathogenic tau protein><pathological change in tau><pathological tau><pathological tau protein><pathophysiology><pathway><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><prescribed medication><primary degenerative dementia><protective effect><resilience><resilient><response to therapy><response to treatment><risk factor for dementia><risk for dementia><senile dementia of the Alzheimer type><serotonin reuptake inhibitor><social role><study design><synapse><tau><tau Proteins><tau abnormality><tau factor><tau intronic mutation><tau mutation><tau pathological change><therapeutic response><therapy response><transgenic trait><treatment response><treatment responsiveness><tryptophan hydroxylase 2><type 2 DM><type II DM><type two diabetes><τ Proteins><τ mutation>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrew Changhun Shin

TEXAS TECH UNIVERSITY, LUBBOCK, TX

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$533,727

FY 2026

Project Title

Serotonin modulated mitochondrial dysfunction in Depression Diabetes and Dementia (3Ds)

Grant Number:

5R01AG071560-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/15/2022

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Our research aims to understand the role of serotonin modulated mitochondrial biogenesis in diabetes, depression, and dementia (Alzheimer's disease, AD). Diabetes and depression are independent risk factors for dementia and worsen the dementia pathology and therapeutic response. Dep...

Research Terms

<5-HT><5-Hydroxytryptamine><5HT><AD dementia><AD patients><Adult-Onset Diabetes Mellitus><Age Months><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's disease patient><Alzheimer's patient><Alzheimers Dementia><Amentia><Ammon Horn><Area><Autophagocytosis><Autoregulation><Behavioral Symptoms><Biogenesis><Biological><Body Tissues><Brain><Brain Nervous System><Brain Stem><Brainstem><CNS Nervous System><Cardiovascular Diseases><Cause of Death><Cell Body><Cell model><Cells><Cellular model><Central Nervous System><Cessation of life><Chronic><Chronic Disease><Chronic Illness><Circadian Rhythms><Citalopram><Clinical><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complementary DNA><Complex><Cornu Ammonis><Cytalopram><D-Glucose><Data><Death><Defect><Dementia><Dextrose><Diabetes Mellitus><Diabetic mouse><Disease><Disease Progression><Disorder><Disturbance in cognition><Dorsal><Dose><Drug Prescribing><Drug Prescriptions><Dysfunction><Encephalon><Energy Expenditure><Energy Metabolism><Enteramine><Exposure to><Functional disorder><Gene Transcription><Genetic Transcription><Glucose><Goals><Hippocampus><Hippophaine><Histones><Homeostasis><Hyperglycemia><Hypothalamic structure><Hypothalamus><Impaired cognition><Impairment><In Vitro><Inflammation><Insulin Resistance><Investigators><Ketosis-Resistant Diabetes Mellitus><Link><MT-bound tau><Maturity-Onset Diabetes Mellitus><Mental Depression><Metabolic><Mice><Mice Mammals><Mitochondria><Modeling><Molecular><Murine><Mus><NIDDM><Nerve Cells><Nerve Degeneration><Nerve Transmitter Substances><Nerve Unit><Nervous System Physiology><Neural Cell><Neural Transmission><Neuraxis><Neurocyte><Neurologic function><Neurological function><Neuron Degeneration><Neurons><Neurotransmitters><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nyctohemeral Rhythm><Obesity><Origin of Life><Outcome><Outcomes Research><Oxidative Stress><Pathogenesis><Pathology><Pathway interactions><Peripheral Nervous System><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Play><Population><Preventive><Primary Senile Degenerative Dementia><Process><Qualifying><RNA Expression><Reporting><Research><Research Design><Research Personnel><Research Subjects><Researchers><Risk Factors><Rodent><Rodentia><Rodents Mammals><Role><SSRI><SSRIs><Selective Serotonin Reuptake Inhibitor><Selective serotonin re-uptake inhibitor><Serotonin><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Study Type><Synapses><Synaptic><Synaptic Transmission><T2 DM><T2D><T2DM><TPH2><Testing><Time><Tissues><Transcription><Transfection><Transgenic Mice><Transgenic Model><Twenty-Four Hour Rhythm><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><aberrant tau><aberrant tau protein><abnormal tau><abnormal tau protein><adiposity><adult onset diabetes><autophagy><biologic><cDNA><cardiovascular disorder><cell resilience><cell resiliency><cellular resilience><cellular resiliency><chronic disorder><circadian process><circadian rhythmicity><co-morbid><co-morbid depression><co-morbid with depression><co-morbidity><co-morbidity with depression><cognitive dysfunction><cognitive loss><comorbid depression><comorbid with depression><comorbidity><comorbidity with depression><corpulence><daily biorhythm><dementia risk><depression><depression co-morbidity><depression comorbidity><diabetes><diabetes mouse model><diabetic><experiment><experimental research><experimental study><experiments><hippocampal><hyperglycemic><hypothalamic><improved><in vitro Model><in vivo><in vivo Model><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><medication prescription><microtubule associated protein tau mutation><microtubule bound tau><microtubule-associated protein tau mutation><microtubule-bound tau><mitochondrial><mitochondrial dysfunction><mouse model><murine model><mutant><mutant tau><mutant tau protein><mutation in microtubule associated protein tau><mutation in microtubule-associated protein tau><nervous system function><neural degeneration><neurodegeneration><neurodegenerative><neurogenesis><neurological degeneration><neuronal><neuronal degeneration><neuroprotection><neuroprotective><pathogenic tau><pathogenic tau gene mutation><pathogenic tau protein><pathological change in tau><pathological tau><pathological tau protein><pathophysiology><pathway><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><prescribed medication><primary degenerative dementia><protective effect><resilience><resilient><response to therapy><response to treatment><risk factor for dementia><risk for dementia><senile dementia of the Alzheimer type><serotonin reuptake inhibitor><social role><study design><synapse><tau><tau Proteins><tau abnormality><tau factor><tau intronic mutation><tau mutation><tau pathological change><therapeutic response><therapy response><transgenic trait><treatment response><treatment responsiveness><tryptophan hydroxylase 2><type 2 DM><type II DM><type two diabetes><τ Proteins><τ mutation>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Colin G Nichols

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$505,994

FY 2026

Project Title

KATP deficiency in hyperinsulinism and diabetes

Grant Number:

5R01DK133838-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/3/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary The long-term goals of this joint project are to understand the mechanisms, role and significance of electrical control of insulin secretion in hyperinsulinism and diabetes. Previous efforts demonstrated the central role of the KATP channel in electrical activity of the pancreatic be...

Research Terms

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Maria Sara Remedi

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$505,994

FY 2026

Project Title

KATP deficiency in hyperinsulinism and diabetes

Grant Number:

5R01DK133838-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/3/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary The long-term goals of this joint project are to understand the mechanisms, role and significance of electrical control of insulin secretion in hyperinsulinism and diabetes. Previous efforts demonstrated the central role of the KATP channel in electrical activity of the pancreatic be...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Estefania Quesada Masachs

UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, CORAL GABLES, FL

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$460,500

FY 2026

Project Title

Specificity, Phenotype and Function of Pancreatic CD8 T Cells in Human Type 1 Diabetes

Grant Number:

5R01AI092453-13

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2024

End Date:

3/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Title: Specificity, Phenotype and Function of Pancreatic CD8 T Cells in Human Type 1 Diabetes Project Summary Human type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing pan- creatic beta cells. CD8 T cells are the most common cell found in insulitis lesions ...

Research Terms

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MARK WILLIAM DI FRANCESCO

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$451,149

FY 2026

Project Title

Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit

Grant Number:

5R01NS125316-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY There is a critical need to determine whether premature vascular disease observed in youth with type 2 diabetes (T2D) extends to the brain. This proposal builds on exciting data generated by our team showing differences in brain structure and clinically meaningful declines in neuroc...

Research Terms

<21+ years old><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><BBB permeabilization><BBB permeable><BMI><BMI percentile><BMI z-score><Blood Plasma><Blood Pressure><Blood Vessels><Body Tissues><Body Weight decreased><Body mass index><Brain><Brain Nervous System><Brain Vascular><Brain Vascular reactivity><Caring><Cerebrovascular Circulation><Cerebrovascular system><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Control Groups><Data><Development><Diabetes Mellitus><Disease><Disorder><Disturbance in cognition><Encephalon><Exercise><Eye><Eyeball><Foundations><Glia><Glial Cells><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Heart><Hemoglobin A(1)><IQ Deficit><Immediate Memory><Impaired cognition><Impairment><Intervention><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Knowledge><Kolliker's reticulum><Laboratories><Leanness><Lipids><Lupus Erythematosus Disseminatus><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Monitor><Morbidity><Morphology><NIDDM><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Neural Cell><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurocognition><Neurocognitive><Neurocognitive Deficit><Neurocyte><Neuroglia><Neuroglial Cells><Neurons><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-neuronal cell><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonneuronal cell><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><Physiologic><Physiological><Plasma><Plasma Serum><Population><Position><Positioning Attribute><Property><Quetelet index><Race><Races><Reporting><Research><Reticuloendothelial System, Serum, Plasma><Risk Factors><SLE><Short-Term Memory><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><T2 DM><T2D><T2DM><Teen><Teenagers><Testing><Thinness><Time><Tissues><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Unit of Measure><Vascular Diseases><Vascular Disorder><Weight Loss><Weight Reduction><Youth><Youth 10-21><Zeugmatography><abnormal brain function><adiposity><adult onset diabetes><adulthood><ages><arterial spin labeling><arterial spin tagging><blood flow in brain><blood vessel disorder><blood vessels in the brain><blood-brain barrier permeabilization><blood-brain barrier permeable><bloodbrain barrier permeabilization><bloodbrain barrier permeable><body weight loss><brain abnormalities><brain behavior><brain blood circulation><brain blood flow><brain blood vessels><brain dysfunction><brain health><brain impairment><brain tissue><brain vascular health><brain vasculature><brain volume><cerebral blood flow><cerebral blood vessel><cerebral circulation><cerebral vascular><cerebral vascular reactivity><cerebral vasculature><cerebro-vascular><cerebrocirculation><cerebrovascular><cerebrovascular blood flow><cerebrovascular health><cerebrovascular reactivity><cerebrovascular vessels><cerebrovasculature><cognitive dysfunction><cognitive loss><cognitive performance><cohort><corpulence><critical period><daily functioning><developmental><diabetes><disseminated lupus erythematosus><dysfunctional brain><experience><glycemic control><gray matter><hemoglobin A1c><image-based method><imaging biomarker><imaging marker><imaging method><imaging modality><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><intelligence quotient deficit><intervention design><juvenile><juvenile human><ketosis resistant diabetes><malleable risk><maturity onset diabetes><member><modifiable risk><mortality><nerve cement><neural imaging><neuro-imaging><neuro-vascular unit><neurocognitive decline><neurocognitive impairment><neuroimaging><neurological imaging><neuronal><neurovascular unit><non-diabetic><non-invasive imaging><nondiabetic><noninvasive imaging><participant retention><peer><premature><prematurity><prevent><preventing><racial><racial background><racial origin><rate of change><recruit><renal><research study><sex><substantia grisea><systemic lupus erythematosis><teen years><teenage><therapy design><treatment design><type 2 DM><type II DM><type two diabetes><vascular><vascular dysfunction><vascular risk factor><vasculopathy><working memory><wt-loss><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

AMY SANGHAVI SHAH

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$451,149

FY 2026

Project Title

Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit

Grant Number:

5R01NS125316-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY There is a critical need to determine whether premature vascular disease observed in youth with type 2 diabetes (T2D) extends to the brain. This proposal builds on exciting data generated by our team showing differences in brain structure and clinically meaningful declines in neuroc...

Research Terms

<21+ years old><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><BBB permeabilization><BBB permeable><BMI><BMI percentile><BMI z-score><Blood Plasma><Blood Pressure><Blood Vessels><Body Tissues><Body Weight decreased><Body mass index><Brain><Brain Nervous System><Brain Vascular><Brain Vascular reactivity><Caring><Cerebrovascular Circulation><Cerebrovascular system><Clinical><Cognition><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Collaborations><Control Groups><Data><Development><Diabetes Mellitus><Disease><Disorder><Disturbance in cognition><Encephalon><Exercise><Eye><Eyeball><Foundations><Glia><Glial Cells><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Heart><Hemoglobin A(1)><IQ Deficit><Immediate Memory><Impaired cognition><Impairment><Intervention><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Urinary System><Knowledge><Kolliker's reticulum><Laboratories><Leanness><Lipids><Lupus Erythematosus Disseminatus><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Monitor><Morbidity><Morphology><NIDDM><NMR Imaging><NMR Tomography><Nerve Cells><Nerve Unit><Neural Cell><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurocognition><Neurocognitive><Neurocognitive Deficit><Neurocyte><Neuroglia><Neuroglial Cells><Neurons><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-neuronal cell><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonneuronal cell><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><Physiologic><Physiological><Plasma><Plasma Serum><Population><Position><Positioning Attribute><Property><Quetelet index><Race><Races><Reporting><Research><Reticuloendothelial System, Serum, Plasma><Risk Factors><SLE><Short-Term Memory><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><T2 DM><T2D><T2DM><Teen><Teenagers><Testing><Thinness><Time><Tissues><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Unit of Measure><Vascular Diseases><Vascular Disorder><Weight Loss><Weight Reduction><Youth><Youth 10-21><Zeugmatography><abnormal brain function><adiposity><adult onset diabetes><adulthood><ages><arterial spin labeling><arterial spin tagging><blood flow in brain><blood vessel disorder><blood vessels in the brain><blood-brain barrier permeabilization><blood-brain barrier permeable><bloodbrain barrier permeabilization><bloodbrain barrier permeable><body weight loss><brain abnormalities><brain behavior><brain blood circulation><brain blood flow><brain blood vessels><brain dysfunction><brain health><brain impairment><brain tissue><brain vascular health><brain vasculature><brain volume><cerebral blood flow><cerebral blood vessel><cerebral circulation><cerebral vascular><cerebral vascular reactivity><cerebral vasculature><cerebro-vascular><cerebrocirculation><cerebrovascular><cerebrovascular blood flow><cerebrovascular health><cerebrovascular reactivity><cerebrovascular vessels><cerebrovasculature><cognitive dysfunction><cognitive loss><cognitive performance><cohort><corpulence><critical period><daily functioning><developmental><diabetes><disseminated lupus erythematosus><dysfunctional brain><experience><glycemic control><gray matter><hemoglobin A1c><image-based method><imaging biomarker><imaging marker><imaging method><imaging modality><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><improved outcome><intelligence quotient deficit><intervention design><juvenile><juvenile human><ketosis resistant diabetes><malleable risk><maturity onset diabetes><member><modifiable risk><mortality><nerve cement><neural imaging><neuro-imaging><neuro-vascular unit><neurocognitive decline><neurocognitive impairment><neuroimaging><neurological imaging><neuronal><neurovascular unit><non-diabetic><non-invasive imaging><nondiabetic><noninvasive imaging><participant retention><peer><premature><prematurity><prevent><preventing><racial><racial background><racial origin><rate of change><recruit><renal><research study><sex><substantia grisea><systemic lupus erythematosis><teen years><teenage><therapy design><treatment design><type 2 DM><type II DM><type two diabetes><vascular><vascular dysfunction><vascular risk factor><vasculopathy><working memory><wt-loss><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Heikki Hyöty

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$439,396

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

5R01DK138372-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Richard E Lloyd

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$439,396

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

5R01DK138372-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kristian F Lynch

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$439,396

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

5R01DK138372-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eoin McKinney

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$439,396

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

5R01DK138372-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joseph Frank Petrosino

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$439,396

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

5R01DK138372-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

AARON W MICHELS

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$411,430

FY 2026

Project Title

Insulin specific T cell response shaped by diabetes protective MHC class II molecules

Grant Number:

5R01DK108868-09

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/11/2017

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary The major genetic determinant in susceptibility to or protection from many autoimmune diseases reside in the human major histocompatibility complex (MHC) that contains the human leukocyte antigen (HLA) region. In type 1 diabetes (T1D), particular HLA class II alleles (e.g. DR4/DQ8) i...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

BRANT Roger BURKHARDT

UNIVERSITY OF SOUTH FLORIDA, TAMPA, FL

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$367,365

FY 2026

Project Title

C. officinalis induction of Nrf2 inhibiting type 1 diabetes

Grant Number:

5R01AT011907-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/25/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

7. Project Summary/Abstract Type 1 diabetes (T1D) is an autoimmune disease initiated by genetic predisposition and environmental influences culminating in the destruction of pancreatic β-cells with irreversible loss of insulin production. Despite strong predictive biomarkers of T1D, there is no cure...

Research Terms

<0-11 years old><21+ years old><Active Oxygen><Address><Adult><Adult Human><Animal Model><Animal Models and Related Studies><Anti-diabetic Agents><Anti-diabetic Drugs><Antioxidants><Appearance><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autophagocytosis><Basal Transcription Factor><Basal transcription factor genes><Beta Cell><Biological><Botanical natural products><Brittle Diabetes Mellitus><Cell Body><Cell Communication and Signaling><Cell Death><Cell Function><Cell Line><Cell Physiology><Cell Process><Cell Signaling><Cell Survival><Cell Viability><CellLine><Cells><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Youth><Children (0-21)><Clinical><Cornus><D-Glucose><Dependence><Development><Dextrose><Disease><Disorder><EC 6.3.2.2><ERYF1><Early treatment><Ethnopharmacology><Experimental Designs><Female><GATA Binding Protein 1><GATA-1><GATA1><GATA1 gene><GATA1 protein><GATA1 transcription factor><GF-1 protein><Gamma-Glutamylcysteinyl Synthetase><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Susceptibility><Genetic propensity><Glucose><Glutamate-Cysteine Ligase><Glutamylcysteine Synthetase><Glutathione Reductase><HO-1 enzyme><HO1><HO2><HSP32><Herbal Medicine><Human><Humulin R><Hydrogen Oxide><Hyperglycemia><IDDM><IPO-B><In Vitro><Inbred NOD Mice><Incidence><Indophenol Oxidase B><Inherited Predisposition><Inherited Susceptibility><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Intervention Strategies><Intracellular Communication and Signaling><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Literature><MNSOD><Manganese Superoxide Dismutase><Measures><Mediating><Methods><Mice><Mice Mammals><Mitochondrial Superoxide Dismutase><Mn Superoxide Dismutase><Mn-SOD><Modality><Modeling><Modern Man><Molecular><Murine><Mus><NF-E1 erythroid-specific transcription factor><NF-E2 protein><NF-E2 transcription factor><NFE1 protein><NFE2 protein><NOD Mouse><Non obese><Non-Obese Diabetic Mice><Nonobese><Nonobese Diabetic Mouse><Novolin R><Nuclear Translocation><Oral><Oral Examination><Oxidative Stress><Oxygen Radicals><Pancreas><Pancreatic><Pancreatic beta Cell><Pancreatic β-Cell><Pathogenesis><Pathway interactions><Patients><Pharmacologic Actions><Plant natural product><Plant-based Natural Product><Plant-derived natural products><Preventative intervention><Preventative measure><Preventative treatment><Preventive measure><Preventive treatment><Pro-Oxidants><Production><Proteins><Proteomics><Reactive Oxygen Species><Reading><Regular Insulin><Reporting><Research><Research Design><Role><SOD2><SOD2 gene><STZ><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Source><Strains Cell Lines><Streptozocin><Streptozotocin><Structure of beta Cell of islet><Study Type><Subcellular Process><Sudden-Onset Diabetes Mellitus><Superoxide Dismutase 2><Symptoms><T1 DM><T1 diabetes><T1D><T1DM><Technology><Therapeutic><Therapeutic Intervention><Toxic effect><Toxicities><Transcription Factor GATA1><Transcription Factor Proto-Oncogene><Transcription factor genes><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Water><Zanosar><adulthood><anti-diabetic><autoimmune condition><autoimmune disorder><autoimmunity disease><autophagy><biologic><biological signal transduction><clinical efficacy><cultured cell line><cytokine><cytotoxic><design><designing><developmental><diabetes pathogenesis><diabetic><drug development><drug resource><early therapy><gamma-Glutamyl-Cysteine Synthetase><genetic vulnerability><genetically predisposed><globin transcription factor 1><heme oxygenase-1><hemeoxygenase 1><hyperglycemic><in vivo><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulitis><interdisciplinary approach><intervention for prevention><intervention therapy><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><male><model of animal><multidisciplinary approach><necrocytosis><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel><nuclear factor-erythroid 1><nuclear factor-erythroid 2><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathway><pharmacologic><pre-clinical><preclinical><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><preservation><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><protein expression><social role><study design><therapeutic candidate><transcription factor><transcription factor NFE-1><treatment group><type 1 diabetes onset><type I diabetes><type one diabetes><youngster><β-cell><β-cells><βCell><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stanley M Stevens

UNIVERSITY OF SOUTH FLORIDA, TAMPA, FL

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$367,365

FY 2026

Project Title

C. officinalis induction of Nrf2 inhibiting type 1 diabetes

Grant Number:

5R01AT011907-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/25/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

7. Project Summary/Abstract Type 1 diabetes (T1D) is an autoimmune disease initiated by genetic predisposition and environmental influences culminating in the destruction of pancreatic β-cells with irreversible loss of insulin production. Despite strong predictive biomarkers of T1D, there is no cure...

Research Terms

<0-11 years old><21+ years old><Active Oxygen><Address><Adult><Adult Human><Animal Model><Animal Models and Related Studies><Anti-diabetic Agents><Anti-diabetic Drugs><Antioxidants><Appearance><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autophagocytosis><Basal Transcription Factor><Basal transcription factor genes><Beta Cell><Biological><Botanical natural products><Brittle Diabetes Mellitus><Cell Body><Cell Communication and Signaling><Cell Death><Cell Function><Cell Line><Cell Physiology><Cell Process><Cell Signaling><Cell Survival><Cell Viability><CellLine><Cells><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Youth><Children (0-21)><Clinical><Cornus><D-Glucose><Dependence><Development><Dextrose><Disease><Disorder><EC 6.3.2.2><ERYF1><Early treatment><Ethnopharmacology><Experimental Designs><Female><GATA Binding Protein 1><GATA-1><GATA1><GATA1 gene><GATA1 protein><GATA1 transcription factor><GF-1 protein><Gamma-Glutamylcysteinyl Synthetase><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Susceptibility><Genetic propensity><Glucose><Glutamate-Cysteine Ligase><Glutamylcysteine Synthetase><Glutathione Reductase><HO-1 enzyme><HO1><HO2><HSP32><Herbal Medicine><Human><Humulin R><Hydrogen Oxide><Hyperglycemia><IDDM><IPO-B><In Vitro><Inbred NOD Mice><Incidence><Indophenol Oxidase B><Inherited Predisposition><Inherited Susceptibility><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Intervention Strategies><Intracellular Communication and Signaling><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Literature><MNSOD><Manganese Superoxide Dismutase><Measures><Mediating><Methods><Mice><Mice Mammals><Mitochondrial Superoxide Dismutase><Mn Superoxide Dismutase><Mn-SOD><Modality><Modeling><Modern Man><Molecular><Murine><Mus><NF-E1 erythroid-specific transcription factor><NF-E2 protein><NF-E2 transcription factor><NFE1 protein><NFE2 protein><NOD Mouse><Non obese><Non-Obese Diabetic Mice><Nonobese><Nonobese Diabetic Mouse><Novolin R><Nuclear Translocation><Oral><Oral Examination><Oxidative Stress><Oxygen Radicals><Pancreas><Pancreatic><Pancreatic beta Cell><Pancreatic β-Cell><Pathogenesis><Pathway interactions><Patients><Pharmacologic Actions><Plant natural product><Plant-based Natural Product><Plant-derived natural products><Preventative intervention><Preventative measure><Preventative treatment><Preventive measure><Preventive treatment><Pro-Oxidants><Production><Proteins><Proteomics><Reactive Oxygen Species><Reading><Regular Insulin><Reporting><Research><Research Design><Role><SOD2><SOD2 gene><STZ><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Source><Strains Cell Lines><Streptozocin><Streptozotocin><Structure of beta Cell of islet><Study Type><Subcellular Process><Sudden-Onset Diabetes Mellitus><Superoxide Dismutase 2><Symptoms><T1 DM><T1 diabetes><T1D><T1DM><Technology><Therapeutic><Therapeutic Intervention><Toxic effect><Toxicities><Transcription Factor GATA1><Transcription Factor Proto-Oncogene><Transcription factor genes><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Water><Zanosar><adulthood><anti-diabetic><autoimmune condition><autoimmune disorder><autoimmunity disease><autophagy><biologic><biological signal transduction><clinical efficacy><cultured cell line><cytokine><cytotoxic><design><designing><developmental><diabetes pathogenesis><diabetic><drug development><drug resource><early therapy><gamma-Glutamyl-Cysteine Synthetase><genetic vulnerability><genetically predisposed><globin transcription factor 1><heme oxygenase-1><hemeoxygenase 1><hyperglycemic><in vivo><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulitis><interdisciplinary approach><intervention for prevention><intervention therapy><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><male><model of animal><multidisciplinary approach><necrocytosis><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel><nuclear factor-erythroid 1><nuclear factor-erythroid 2><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathway><pharmacologic><pre-clinical><preclinical><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><preservation><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><protein expression><social role><study design><therapeutic candidate><transcription factor><transcription factor NFE-1><treatment group><type 1 diabetes onset><type I diabetes><type one diabetes><youngster><β-cell><β-cells><βCell><♀><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ANNE R CAPPOLA

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$325,000

FY 2026

Project Title

T4/T3 Therapy in Hypothyroidism

Grant Number:

5R01DK137207-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2024

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Modified Project Summary/Abstract Section Day-to-day self-management by adults with type 2 diabetes is essential to avoid diabetes complications, yet successful self-management behaviors remain difficult for many to achieve and sustain. Adults with diabetes have rapidly evolving ways to track their ...

Research Terms

<21+ years old><Accelerometer><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Amputation><Apoplexy><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Brain Vascular Accident><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic><Clinical><Clinical Trials><Complications of Diabetes Mellitus><Conditioning Therapy><Continuous Glucose Monitor><D-Glucose><Data><Data Display><Data Reporting><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Drugs><Enrollment><Feedback><Friends><Future><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Habits><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Status><Health behavior><Hemoglobin A(1)><Hypothyroidism><Informal Social Control><Intervention><Intervention Trial><Interventional trial><Interview><Ketosis-Resistant Diabetes Mellitus><Kidney Failure><Kidney Insufficiency><Knowledge><Level of Health><Link><Maturity-Onset Diabetes Mellitus><Medication><Methods><Modernization><Monitor><Motivation><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Patients><Persons><Pharmaceutical Preparations><Preparation><Protocol><Protocols documentation><Public Health><QOL><Quality of life><Randomization trial><Randomized><Renal Failure><Renal Insufficiency><Research><Risk Reduction><Sampling><Self Determination><Self Management><Self Regulation><Site><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stroke><Structure><T2 DM><T2D><T2DM><Techniques><Testing><Text><Time><Treatment Efficacy><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visualization><accelerometry><activity monitor><activity tracker><adult onset diabetes><adulthood><arm><behavior change><behavior intervention><behavioral intervention><brain attack><cerebral vascular accident><cerebrovascular accident><clinical research site><clinical site><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><data driven platform><data platform><data representation><data representations><data visualization><design><designing><diabetes><diabetes distress><diabetes education><diabetes self-care><diabetes self-management><diabetes-related distress><diabetes-specific distress><distress related to diabetes><distress specific to diabetes><drug/agent><efficacy clinical trial><efficacy trial><empowerment><enroll><evidence base><feasibility trial><fitbit><glucometer><glucose meter><glucose monitor><health data><health level><health literacy><health related behavior><hemoglobin A1c><human centered design><improved><innovate><innovation><innovative><insight><interactive data visualization><interactive visualization><internet based platform><internet platform><intervention efficacy><ketosis resistant diabetes><maturity onset diabetes><pilot test><pilot trial><preparations><public health relevance><randomisation><randomization><randomized trial><randomly assigned><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><response><risk-reducing><stroked><strokes><success><theories><therapeutic efficacy><therapy efficacy><tool><trend><type 2 DM><type II DM><type two diabetes><wearable health monitor><wearable health tracker><wearable monitor><web based platform><web based system><web enabled platform><web platform>

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Helena Safavi-Hemami

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$318,584

FY 2026

Project Title

Discovery and design of novel insulin evologs from venomous marine cone snails

Grant Number:

5R01DK139317-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY Insulin is a pancreatic peptide hormone that is of critical importance for glucose homeostasis. Disruption of insulin production or function can result in diabetes mellitus. Insulin therapy is the only effective treatment for type 1 diabetes (T1D) and is used by many people with type 2 diabe...

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Nicole L Spartano

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$317,651

FY 2026

Project Title

Continuous glucose monitoring: determinants and prediction of diabetes mellitus development in the Framingham Heart Study

Grant Number:

5R01DK129305-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Abstract Almost half of adults have either diabetes mellitus (DM) or prediabetes (preDM), but many of those have undiagnosed conditions. Current DM diagnosis and risk prediction are based on single “snapshot” measurements, including fasting blood glucose, postprandial glucose, and hemoglobin...

Research Terms

<21+ years old><Active Follow-up><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><American><Awareness><BMI><BMI percentile><BMI z-score><Behavior><Biochemical><Biological Markers><Blood><Blood Glucose><Blood Reticuloendothelial System><Blood Sample><Blood Sugar><Blood specimen><Body System><Body mass index><Brittle Diabetes Mellitus><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Categories><Characteristics><Clinical><Clinical Markers><Communities><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Development><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes prevention><Diabetes-Related Complications><Diabetic Complications><Diagnosis><Diet><Dietary Practices><Disease Frequency Surveys><Dysfunction><Endocrinologist><Epidemiology><Exhibits><Family Medical History><Family Medical History Epidemiology><Family history of><Fasting><Fingers><Framingham Heart Study><Functional disorder><Future><GI microbiome><Generations><Genetic><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Technology><Health Technology><Heart Vascular><Hemoglobin A(1)><History><Humulin R><Hypoglycemia><IDDM><Individual><Insulin><Insulin-Dependent Diabetes Mellitus><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Life Style><Lifestyle><Link><Managed Care><Maturity-Onset Diabetes Mellitus><Measurement><Measures><Metabolic dysfunction><Modification><Monitor><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Organ System><Participant><Patient Self-Report><Patients><Pattern><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Physical activity><Physiopathology><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predicting Risk><Prevalence><Publishing><Quetelet index><Recording of previous events><Regular Insulin><Research Personnel><Researchers><Risk><Sampling><Self-Report><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Woman><active followup><adiposity><adult onset diabetes><adulthood><ages><bacteria in the gut><bio-markers><biologic marker><biomarker><cardiorespiratory fitness><cardiorespiratory health><cardiovascular disorder><circulatory system><clinical biomarkers><clinically useful biomarkers><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><cross-sectional research study><deep learning based model><deep learning model><developmental><diabetes><diabetes management><diabetes mellitus management><diabetes risk><diabetic management><dietary pattern><diets><digestive tract microbiome><enteric microbiome><epidemiologic><epidemiological><falls><fasted><fasting glucose><fasting plasma glucose><fasts><follow up><follow up assessment><follow-up><followed up><followup><followup assessment><forecasting risk><gastrointestinal microbiome><glycemic control><gut bacteria><gut microbiome><gut-associated microbiome><hemoglobin A1c><high risk><histories><hypoglycemic><hypoglycemic episodes><improved><insulin dependent diabetes><insulin dependent type 1><interstitial><intestinal biome><intestinal microbiome><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><m-Health><mHealth><maturity onset diabetes><mobile health><monitoring device><multi-ethnic><multiethnic><novel><pathophysiology><pharmaceutical><polygenetic risk scores><polygenic risk score><pre-diabetes><pre-diabetic><prediabetic><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><recruit><response><risk prediction><risk predictions><tool><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes>

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Michael Lee Stitzel

JACKSON LABORATORY, BAR HARBOR, ME

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$891,736

FY 2026

Project Title

Dissecting cell type-specific genetic programming of islet (dys)function in type 2 diabetes

Grant Number:

5R01DK118011-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/3/2020

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Type 2 diabetes (T2D) is a complex genetic disease that occurs when pancreatic islets cannot secrete sufficient insulin to overcome peripheral tissue insulin resistance. Genome-wide association studies (GWAS) have identified DNA sequence variants associated with T2D (T2D SNVs) in >60...

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Qibin Qi

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$887,696

FY 2026

Project Title

Blood proteomic signatures of diabetes and gut dysbiosis

Grant Number:

1R01DK143633-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2026

End Date:

11/30/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary/Abstract The Hispanic/Latino population, one of the fastest growing segments in the US, is disproportionately affected by type 2 diabetes (T2D), but the underlying mechanisms are largely unknown. There is an urgent need to better understand this phenomenon thus to develop more effective appr...

Research Terms

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Bing Yu

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$887,696

FY 2026

Project Title

Blood proteomic signatures of diabetes and gut dysbiosis

Grant Number:

1R01DK143633-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2026

End Date:

11/30/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary/Abstract The Hispanic/Latino population, one of the fastest growing segments in the US, is disproportionately affected by type 2 diabetes (T2D), but the underlying mechanisms are largely unknown. There is an urgent need to better understand this phenomenon thus to develop more effective appr...

Research Terms

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Jill Weissberg-Benchell

BOSTON MEDICAL CENTER, BOSTON, MA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$844,525

FY 2026

Project Title

Effectiveness Trial to Support Adoption of Hybrid Closed Loop Therapy in Underserved Adults with Type 1 Diabetes: Impact of System Functionality and Features on Lived Experience

Grant Number:

5R01DK138309-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Individuals with type 1 diabetes (T1D) from certain ethnic/racial minority and lower socio-economic groups have higher average A1c levels and rates of hospitalizations, complications, and mortality than the general T1D population. However, the efficacy trials establishing the benefits of hybrid clo...

Research Terms

<21+ years old><Active Follow-up><Address><Adoption><Adult><Adult Human><Algorithms><Automation><Behavioral><Bionics><Body Weight><Boston><Brittle Diabetes Mellitus><Caring><Clinic><Clinical><Collaborations><Communities><Continuous Glucose Monitor><D-Glucose><Data><Decision Aid><Development><Devices><Dextrose><Diabetes Mellitus><Diabetic Acidosis><Diabetic Ketoacidosis><Diabetic Ketosis><Disparities><Disparity><Ecological momentary assessment><Educational workshop><Effectiveness><Eligibility><Eligibility Determination><Ethnic Origin><Ethnicity><Evaluation><Event><Funding><Glucose><Health Care><Humulin R><Hybrids><Hypoglycemia><IDDM><Individual><Individuals from minority><Individuals of minority><Injection of therapeutic agent><Injections><Insulin><Insulin-Dependent Diabetes Mellitus><Insurance Coverage><Insurance Status><International><Interview><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Lead><Life><Lived experience><Lived experiences><Low income><Medical><Medical Technology><Medical center><Methodology><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Modernization><NIH><National Institutes of Health><Novolin R><Pancreas><Pancreatic><Patient Education><Patient Instruction><Patient Preferences><Patient Selection><Patient Training><Patients><Pb element><Perception><Persons><Population><Prevalence><Primary Care><Protocol Screening><Psychologist><Pump><Qualifying><Randomized><Regular Insulin><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Factors><Role><Running><Rural Population><Rural group><Rural people><Safety><Scientist><Socio-economic status><Socioeconomic Status><Structure><Sudden-Onset Diabetes Mellitus><Survey Instrument><Surveys><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Time><Training><Translations><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Underserved Population><United States National Institutes of Health><Weight Gain><Weight Increase><Workshop><active followup><adulthood><applied learning><arm><assess effectiveness><body weight gain><body weight increase><clinical decision-making><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><day shift><determine effectiveness><developmental><diabetes><diabetes self-care><diabetes self-management><diabetic ketoacidotic><disparity in health><effectiveness assessment><effectiveness evaluation><effectiveness study><effectiveness trial><efficacy trial><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><evaluate effectiveness><examine effectiveness><expectation><experience><follow up><follow-up><followed up><followup><hands-on learning><health disparity><heavy metal Pb><heavy metal lead><high risk group><high risk individual><high risk people><high risk population><hospitalization rates><hypoglycemic><hypoglycemic episodes><implementation tool><improved><individual patient><injection therapy><instrument><insulin dependent diabetes><insulin dependent type 1><interactive engagement><interactive learning><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><medically under served><medically underserved><mortality><multidisciplinary><night shift><night work><novel><operation><operations><patient population><preference><primary outcome><programs><psychosocial><public health insurance><public insurance><racial minority><racial minority group><racial minority individual><racial minority people><racial minority population><randomisation><randomization><randomized effectiveness trial><randomly assigned><recruit><rural individual><safety net><secondary outcome><shared decision making><shift work><shiftwork><social><social role><socio-economic><socio-economic position><socio-economically><socioeconomic position><socioeconomically><socioeconomics><stressor><support tools><tool><translation><type I diabetes><type one diabetes><under served community><under served group><under served individual><under served people><under served population><underserved community><underserved group><underserved individual><underserved people><user centered design><wt gain>

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Howard A Wolpert

BOSTON MEDICAL CENTER, BOSTON, MA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$844,525

FY 2026

Project Title

Effectiveness Trial to Support Adoption of Hybrid Closed Loop Therapy in Underserved Adults with Type 1 Diabetes: Impact of System Functionality and Features on Lived Experience

Grant Number:

5R01DK138309-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Individuals with type 1 diabetes (T1D) from certain ethnic/racial minority and lower socio-economic groups have higher average A1c levels and rates of hospitalizations, complications, and mortality than the general T1D population. However, the efficacy trials establishing the benefits of hybrid clo...

Research Terms

<21+ years old><Active Follow-up><Address><Adoption><Adult><Adult Human><Algorithms><Automation><Behavioral><Bionics><Body Weight><Boston><Brittle Diabetes Mellitus><Caring><Clinic><Clinical><Collaborations><Communities><Continuous Glucose Monitor><D-Glucose><Data><Decision Aid><Development><Devices><Dextrose><Diabetes Mellitus><Diabetic Acidosis><Diabetic Ketoacidosis><Diabetic Ketosis><Disparities><Disparity><Ecological momentary assessment><Educational workshop><Effectiveness><Eligibility><Eligibility Determination><Ethnic Origin><Ethnicity><Evaluation><Event><Funding><Glucose><Health Care><Humulin R><Hybrids><Hypoglycemia><IDDM><Individual><Individuals from minority><Individuals of minority><Injection of therapeutic agent><Injections><Insulin><Insulin-Dependent Diabetes Mellitus><Insurance Coverage><Insurance Status><International><Interview><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Lead><Life><Lived experience><Lived experiences><Low income><Medical><Medical Technology><Medical center><Methodology><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Modernization><NIH><National Institutes of Health><Novolin R><Pancreas><Pancreatic><Patient Education><Patient Instruction><Patient Preferences><Patient Selection><Patient Training><Patients><Pb element><Perception><Persons><Population><Prevalence><Primary Care><Protocol Screening><Psychologist><Pump><Qualifying><Randomized><Regular Insulin><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Factors><Role><Running><Rural Population><Rural group><Rural people><Safety><Scientist><Socio-economic status><Socioeconomic Status><Structure><Sudden-Onset Diabetes Mellitus><Survey Instrument><Surveys><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Time><Training><Translations><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Underserved Population><United States National Institutes of Health><Weight Gain><Weight Increase><Workshop><active followup><adulthood><applied learning><arm><assess effectiveness><body weight gain><body weight increase><clinical decision-making><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><day shift><determine effectiveness><developmental><diabetes><diabetes self-care><diabetes self-management><diabetic ketoacidotic><disparity in health><effectiveness assessment><effectiveness evaluation><effectiveness study><effectiveness trial><efficacy trial><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><evaluate effectiveness><examine effectiveness><expectation><experience><follow up><follow-up><followed up><followup><hands-on learning><health disparity><heavy metal Pb><heavy metal lead><high risk group><high risk individual><high risk people><high risk population><hospitalization rates><hypoglycemic><hypoglycemic episodes><implementation tool><improved><individual patient><injection therapy><instrument><insulin dependent diabetes><insulin dependent type 1><interactive engagement><interactive learning><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><medically under served><medically underserved><mortality><multidisciplinary><night shift><night work><novel><operation><operations><patient population><preference><primary outcome><programs><psychosocial><public health insurance><public insurance><racial minority><racial minority group><racial minority individual><racial minority people><racial minority population><randomisation><randomization><randomized effectiveness trial><randomly assigned><recruit><rural individual><safety net><secondary outcome><shared decision making><shift work><shiftwork><social><social role><socio-economic><socio-economic position><socio-economically><socioeconomic position><socioeconomically><socioeconomics><stressor><support tools><tool><translation><type I diabetes><type one diabetes><under served community><under served group><under served individual><under served people><under served population><underserved community><underserved group><underserved individual><underserved people><user centered design><wt gain>

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MOSHE LEVI

GEORGETOWN UNIVERSITY, WASHINGTON, DC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$831,580

FY 2026

Project Title

Role of Glycosphingolipids in Kidney Disease in Diabetes and Obesity

Grant Number:

5R01DK139676-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/20/2025

End Date:

11/30/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Obesity and diabetes continue to be leading causes of chronic kidney disease (CKD). In our models of diabetes and obesity, we have found increased renal glycosphingolipids which are associated with impaired mitochondrial function, increased inflammatory T cells (Th17 cells), and progression of renal...

Research Terms

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Jeannette Michele Beasley

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$830,133

FY 2026

Project Title

BRinging the Diabetes Prevention Program to GEriatric Populations (BRIDGE)

Grant Number:

5R01DK127916-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2021

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT ABSTRACT Over 24 million Americans are ≥65 years and have prediabetes. Prediabetes can be addressed using a public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were ages 60 and over, the diet and physical activity intervention conferred a 71% r...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Active Follow-up><Address><Adherence><Adopted><Adult><Adult Human><Age><Aged 65 and Over><American><Assess implementation><Body Weight decreased><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Clinic><Clinical><Communities><Consolidated Framework for Implementation Research><Consolidated Framework for Implementation Science><Consolidated Framework for Implementing Change><Cost Analyses><Cost Analysis><Data><Dentition><Diabetes Mellitus><Diabetes prevention><Diagnosis><Diet><Diminished Vision><Effectiveness><Elderly><Electronic Health Record><Eligibility><Eligibility Determination><Evidence based intervention><Faculty><Federally Qualified Health Center><Future><Geriatrics><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Group Practice><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Healthy diet><Hearing Loss><Hemoglobin A(1)><Hospital Admission><Hospitalization><Hospitals><Hypoacuses><Hypoacusis><Implementation assessment><Incidence><Individual><Institution><Intervention><Interview><Length of Stay><Life Style><Lifestyle><Low Vision><Measures><Medicare><Methodology><Monitor><Number of Days in Hospital><Older Population><Outcome><Outcome Assessment><Partial Sight><Participant><Patients><Persons><Physical activity><Policies><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Preventative strategy><Prevention strategy><Preventive strategy><Private Practice><Process><Protocol Screening><Public Health><Qualifying><RE-AIM><Randomized><Randomized, Controlled Trials><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Reduced Vision><Research><Risk><Risk Reduction><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Self Efficacy><Seminal><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social Support System><Social support><Subnormal Vision><Support System><Technology><Time><Title 18><Travel><Visit><Visual impairment><Weight><Weight Loss><Weight Reduction><Weights and Measures><Work><above age 65><acceptability and feasibility><active followup><adulthood><advanced age><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><arm><assess cost><assess effectiveness><balanced diet><barriers to implementation><behavior change><body weight loss><care as usual><compare effectiveness><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost assessment><cost evaluation><design><designing><determine effectiveness><diabetes><diabetes prevention program><diets><digital><dysfunctional hearing><effectiveness assessment><effectiveness evaluation><effectiveness outcome><effectiveness testing><effectiveness-related outcomes><effectiveness/implementation hybrid study><effectiveness/implementation study><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evaluate cost><evaluate effectiveness><evaluate implementation><evaluation of implementation><evidence base><examine cost><examine effectiveness><exercise intervention><exercise program><experience><fitness program><follow up><follow-up><followed up><followup><geriatric><geriatric medicine><good diet><health care settings><health insurance for disabled><healthy lifestyle><healthy weight><hearing challenged><hearing defect><hearing deficient><hearing deficit><hearing difficulty><hearing dysfunction><hearing impairment><hemoglobin A1c><hospital days><hospital length of stay><hospital stay><human old age (65+)><implementation barriers><implementation challenges><implementation cost><implementation evaluation><implementation framework><implementation investment><implementation outcomes><implementation research framework><implementation science framework><implementation study><informant><intervention program><life style intervention><lifestyle intervention><old age><older adult><older adulthood><older groups><older individuals><older person><over 65 years><physical activity intervention><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><primary outcome><programs><randomisation><randomization><randomized control trial><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><rural locality><rural place><rural setting><secondary outcome><senior citizen><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social support network><systemic barrier><systemic hurdle><systemic obstacle><telehealth><theories><tool><treatment as usual><trial design><usual care><vision impairment><visually impaired><weights><wt-loss><≥65 years>

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JOSHUA CHODOSH

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$830,133

FY 2026

Project Title

BRinging the Diabetes Prevention Program to GEriatric Populations (BRIDGE)

Grant Number:

5R01DK127916-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2021

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT ABSTRACT Over 24 million Americans are ≥65 years and have prediabetes. Prediabetes can be addressed using a public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were ages 60 and over, the diet and physical activity intervention conferred a 71% r...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Active Follow-up><Address><Adherence><Adopted><Adult><Adult Human><Age><Aged 65 and Over><American><Assess implementation><Body Weight decreased><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Clinic><Clinical><Communities><Consolidated Framework for Implementation Research><Consolidated Framework for Implementation Science><Consolidated Framework for Implementing Change><Cost Analyses><Cost Analysis><Data><Dentition><Diabetes Mellitus><Diabetes prevention><Diagnosis><Diet><Diminished Vision><Effectiveness><Elderly><Electronic Health Record><Eligibility><Eligibility Determination><Evidence based intervention><Faculty><Federally Qualified Health Center><Future><Geriatrics><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Group Practice><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Healthy diet><Hearing Loss><Hemoglobin A(1)><Hospital Admission><Hospitalization><Hospitals><Hypoacuses><Hypoacusis><Implementation assessment><Incidence><Individual><Institution><Intervention><Interview><Length of Stay><Life Style><Lifestyle><Low Vision><Measures><Medicare><Methodology><Monitor><Number of Days in Hospital><Older Population><Outcome><Outcome Assessment><Partial Sight><Participant><Patients><Persons><Physical activity><Policies><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Preventative strategy><Prevention strategy><Preventive strategy><Private Practice><Process><Protocol Screening><Public Health><Qualifying><RE-AIM><Randomized><Randomized, Controlled Trials><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Reduced Vision><Research><Risk><Risk Reduction><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Self Efficacy><Seminal><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social Support System><Social support><Subnormal Vision><Support System><Technology><Time><Title 18><Travel><Visit><Visual impairment><Weight><Weight Loss><Weight Reduction><Weights and Measures><Work><above age 65><acceptability and feasibility><active followup><adulthood><advanced age><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><arm><assess cost><assess effectiveness><balanced diet><barriers to implementation><behavior change><body weight loss><care as usual><compare effectiveness><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost assessment><cost evaluation><design><designing><determine effectiveness><diabetes><diabetes prevention program><diets><digital><dysfunctional hearing><effectiveness assessment><effectiveness evaluation><effectiveness outcome><effectiveness testing><effectiveness-related outcomes><effectiveness/implementation hybrid study><effectiveness/implementation study><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evaluate cost><evaluate effectiveness><evaluate implementation><evaluation of implementation><evidence base><examine cost><examine effectiveness><exercise intervention><exercise program><experience><fitness program><follow up><follow-up><followed up><followup><geriatric><geriatric medicine><good diet><health care settings><health insurance for disabled><healthy lifestyle><healthy weight><hearing challenged><hearing defect><hearing deficient><hearing deficit><hearing difficulty><hearing dysfunction><hearing impairment><hemoglobin A1c><hospital days><hospital length of stay><hospital stay><human old age (65+)><implementation barriers><implementation challenges><implementation cost><implementation evaluation><implementation framework><implementation investment><implementation outcomes><implementation research framework><implementation science framework><implementation study><informant><intervention program><life style intervention><lifestyle intervention><old age><older adult><older adulthood><older groups><older individuals><older person><over 65 years><physical activity intervention><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><primary outcome><programs><randomisation><randomization><randomized control trial><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><rural locality><rural place><rural setting><secondary outcome><senior citizen><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social support network><systemic barrier><systemic hurdle><systemic obstacle><telehealth><theories><tool><treatment as usual><trial design><usual care><vision impairment><visually impaired><weights><wt-loss><≥65 years>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Guoqiang Gu

VANDERBILT UNIVERSITY, Nashville, TN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$807,114

FY 2026

Project Title

Microtubule Regulation of Pancreatic Beta Cell Function and Diabetes

Grant Number:

2R01DK106228-10A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2016

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary Islet β cells secrete insulin on stimuli to regulate whole-body glucose homeostasis. Deregulating this function results in type 2 diabetes (T2D) or hypoglycemia. To avoid pathology, β cells need proper numbers of insulin granules (IGs) positioned to their secretion sites at the cell membrane...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

William Holmes

VANDERBILT UNIVERSITY, Nashville, TN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$807,114

FY 2026

Project Title

Microtubule Regulation of Pancreatic Beta Cell Function and Diabetes

Grant Number:

2R01DK106228-10A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2016

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary Islet β cells secrete insulin on stimuli to regulate whole-body glucose homeostasis. Deregulating this function results in type 2 diabetes (T2D) or hypoglycemia. To avoid pathology, β cells need proper numbers of insulin granules (IGs) positioned to their secretion sites at the cell membrane...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Irina Kaverina

VANDERBILT UNIVERSITY, Nashville, TN

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$807,114

FY 2026

Project Title

Microtubule Regulation of Pancreatic Beta Cell Function and Diabetes

Grant Number:

2R01DK106228-10A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2016

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Summary Islet β cells secrete insulin on stimuli to regulate whole-body glucose homeostasis. Deregulating this function results in type 2 diabetes (T2D) or hypoglycemia. To avoid pathology, β cells need proper numbers of insulin granules (IGs) positioned to their secretion sites at the cell membrane...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alan D Attie

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$777,498

FY 2026

Project Title

The Diversity Outbred Diabetes Project

Grant Number:

2R01DK101573-10A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2014

End Date:

12/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Type 2 diabetes (T2D) is characterized by the inability of pancreatic islet β-cells to meet insulin demands, often due to genetic and environmental factors that disrupt β-cell function. Most genetic variants associated with T2D affect the differentiation, survival, and nutri...

Research Terms

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TRACEY MCLAUGHLIN

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$714,298

FY 2026

Project Title

Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention

Grant Number:

5R01DK139472-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT T2D and prediabetes are defined by measures of glucose elevation, but the underlying physiology is complex and differs between individuals: this heterogeneity is likely to drive differences in the course of diabetes, including development of comorbidities and response to treatment. Thus, wh...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Age><Approaches to prevention><BMI><BMI percentile><BMI z-score><Beta Cell><Biological><Biological Markers><Biological Response Modifier Therapy><Biological Therapy><Biology><Body Weight decreased><Body mass index><CLIA accredited><CLIA approved><CLIA certified><CLIA compliant><CLIA licensed><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Classification><Clinical><Clinical Data><Complex><Consensus><D-Glucose><Defect><Development><Dextrose><Diabetes Mellitus><Diabetes prevention><Dimethylbiguanidine><Dimethylguanylguanidine><Enrollment><Fats><Fatty acid glycerol esters><Frequencies><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Heart Vascular><Hemoglobin A(1)><Hepatic><Heterogeneity><Hyperglycemia><Individual><Infrastructure><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intervention><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><Knowledge><Laboratories><Maturity-Onset Diabetes Mellitus><Measures><Medical Records><Medicine><Mediterranean Diet><Menopause><Metabolic><Metformin><Methods><Microbiomics><Modeling><Molecular Fingerprinting><Molecular Profiling><Multiomic Data><Muscle><Muscle Tissue><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Organism-Level Process><Organismal Process><Participant><Pathway interactions><Patients><Personalized medical approach><Phenotype><Physiologic><Physiologic Processes><Physiological><Physiological Processes><Physiology><Pre-DM><Precision Health><Prediabetes><Prediabetes syndrome><Prediabetic State><Prediction of Response to Therapy><Predictive Value><Preventative intervention><Preventative treatment><Prevention><Prevention approach><Preventive treatment><Process><Proteomics><Quetelet index><Race><Races><Randomized><Renal Disease><Research><Research Resources><Resources><Risk Marker><Running><Sampling><Sequential Treatment><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stratification><Subcellular Process><Systematics><T2 DM><T2D><T2DM><Testing><Time><Treatment Period><Treatment Protocols><Treatment Regimen><Treatment Schedule><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight Loss><Weight Reduction><adult onset diabetes><adulthood><ages><bio-markers><biologic><biologic marker><biological therapeutic><biological treatment><biologically based therapeutics><biomarker><biotherapeutics><biotherapy><blood glucose regulation><body weight loss><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><circulatory system><co-morbid><co-morbidity><cohort><comorbidity><developmental><diabetes><diabetic><enroll><experience><fasting glucose><glucose control><glucose homeostasis><glucose regulation><hemoglobin A1c><hyperglycemic><individual heterogeneity><individual variability><individual variation><individualized approach><insulin resistant><insulin tolerance><intervention arm><intervention for prevention><ketosis resistant diabetes><kidney disorder><lipidomics><liraglutide><maturity onset diabetes><metabolic phenotype><metabolism measurement><metabolomics><metabonomics><metabotype><microbiome research><microbiome science><microbiome studies><molecular profile><molecular signature><multiomics><multiple omic data><multiple omics><muscular><novel><panomics><pathway><personalized approach><pre-diabetes><pre-diabetic><precision approach><precision medicine><precision-based medicine><prediabetic><predict responsiveness><predict therapeutic response><predict therapy response><predicting response><predictive signature><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary end point><primary endpoint><racial><racial background><racial origin><randomisation><randomization><randomly assigned><renal disorder><response><response to therapy><response to treatment><risk predictor><risk predictors><secondary end point><secondary endpoint><sex><skills><tailored approach><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic response><therapy prediction><therapy response><trait><transcriptomics><treatment arm><treatment days><treatment duration><treatment prediction><treatment response><treatment response prediction><treatment responsiveness><type 2 DM><type II DM><type two diabetes><wt-loss><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MICHAEL P. SNYDER

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$714,298

FY 2026

Project Title

Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention

Grant Number:

5R01DK139472-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT T2D and prediabetes are defined by measures of glucose elevation, but the underlying physiology is complex and differs between individuals: this heterogeneity is likely to drive differences in the course of diabetes, including development of comorbidities and response to treatment. Thus, wh...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Age><Approaches to prevention><BMI><BMI percentile><BMI z-score><Beta Cell><Biological><Biological Markers><Biological Response Modifier Therapy><Biological Therapy><Biology><Body Weight decreased><Body mass index><CLIA accredited><CLIA approved><CLIA certified><CLIA compliant><CLIA licensed><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Classification><Clinical><Clinical Data><Complex><Consensus><D-Glucose><Defect><Development><Dextrose><Diabetes Mellitus><Diabetes prevention><Dimethylbiguanidine><Dimethylguanylguanidine><Enrollment><Fats><Fatty acid glycerol esters><Frequencies><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Heart Vascular><Hemoglobin A(1)><Hepatic><Heterogeneity><Hyperglycemia><Individual><Infrastructure><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intervention><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><Knowledge><Laboratories><Maturity-Onset Diabetes Mellitus><Measures><Medical Records><Medicine><Mediterranean Diet><Menopause><Metabolic><Metformin><Methods><Microbiomics><Modeling><Molecular Fingerprinting><Molecular Profiling><Multiomic Data><Muscle><Muscle Tissue><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Organism-Level Process><Organismal Process><Participant><Pathway interactions><Patients><Personalized medical approach><Phenotype><Physiologic><Physiologic Processes><Physiological><Physiological Processes><Physiology><Pre-DM><Precision Health><Prediabetes><Prediabetes syndrome><Prediabetic State><Prediction of Response to Therapy><Predictive Value><Preventative intervention><Preventative treatment><Prevention><Prevention approach><Preventive treatment><Process><Proteomics><Quetelet index><Race><Races><Randomized><Renal Disease><Research><Research Resources><Resources><Risk Marker><Running><Sampling><Sequential Treatment><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stratification><Subcellular Process><Systematics><T2 DM><T2D><T2DM><Testing><Time><Treatment Period><Treatment Protocols><Treatment Regimen><Treatment Schedule><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight Loss><Weight Reduction><adult onset diabetes><adulthood><ages><bio-markers><biologic><biologic marker><biological therapeutic><biological treatment><biologically based therapeutics><biomarker><biotherapeutics><biotherapy><blood glucose regulation><body weight loss><cardiovascular disorder><cardiovascular risk><cardiovascular risk factor><circulatory system><co-morbid><co-morbidity><cohort><comorbidity><developmental><diabetes><diabetic><enroll><experience><fasting glucose><glucose control><glucose homeostasis><glucose regulation><hemoglobin A1c><hyperglycemic><individual heterogeneity><individual variability><individual variation><individualized approach><insulin resistant><insulin tolerance><intervention arm><intervention for prevention><ketosis resistant diabetes><kidney disorder><lipidomics><liraglutide><maturity onset diabetes><metabolic phenotype><metabolism measurement><metabolomics><metabonomics><metabotype><microbiome research><microbiome science><microbiome studies><molecular profile><molecular signature><multiomics><multiple omic data><multiple omics><muscular><novel><panomics><pathway><personalized approach><pre-diabetes><pre-diabetic><precision approach><precision medicine><precision-based medicine><prediabetic><predict responsiveness><predict therapeutic response><predict therapy response><predicting response><predictive signature><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary end point><primary endpoint><racial><racial background><racial origin><randomisation><randomization><randomly assigned><renal disorder><response><response to therapy><response to treatment><risk predictor><risk predictors><secondary end point><secondary endpoint><sex><skills><tailored approach><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic response><therapy prediction><therapy response><trait><transcriptomics><treatment arm><treatment days><treatment duration><treatment prediction><treatment response><treatment response prediction><treatment responsiveness><type 2 DM><type II DM><type two diabetes><wt-loss><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KITT F PETERSEN

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$709,296

FY 2026

Project Title

Targeting hepatic mitochondrial oxidation to treat NAFLD, NASH and type 2 diabetes

Grant Number:

5R01DK135645-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/18/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD) are emerging as two of the most critical global health challenges of the 21st century. NAFLD is estimated to affect up to one third of the general population, and NAFLD is nearly universally present in patients with T2D, with 75-100%...

Research Terms

<0-11 years old><Address><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Affect><Agonist><Antidiabetic Hormone><Body Weight decreased><Child><Child Youth><Children (0-21)><Chronic><Cirrhosis><Clinical Trials><Data><Development><Diabetes Mellitus><Disease><Disorder><Elderly><Fats><Fatty Liver><Fatty acid glycerol esters><GLP-1><General Population><General Public><Glp-1><Glucagon><Glucagon Receptor><Gluconeogenesis><Glukagon><Grant><HG-Factor><Hepatic><Hepatic Disorder><Hepatic mitochondria><Human><Hyperglycemic-Glycogenolytic Factor><Individual><Infusion><Infusion procedures><Insulin Resistance><Ketosis-Resistant Diabetes Mellitus><Lipids><Liver><Liver Mitochondria><Liver Steatosis><Liver diseases><Maturity-Onset Diabetes Mellitus><Measures><Methods><Mitochondria><Modern Man><Muscle Mitochondria><NAFLD><NASH><NHP models><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Participant><Pathogenesis><Patients><Phase><Physiologic><Physiological><Pyruvate Carboxylase><Resolution><Rodent><Rodent Model><Rodentia><Rodents Mammals><Role><Sarcosomes><Science><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Steatohepatitis><T2 DM><T2D><T2DM><Testing><Tracer><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight><Weight Loss><Weight Reduction><adult onset diabetes><advanced age><awake><body weight loss><cirrhotic><developmental><diabetes><fat metabolism><geriatric><global health><glucagon-like peptide 1><glucose biosynthesis><glucose metabolism><hepatic body system><hepatic disease><hepatic gluconeogenesis><hepatic metabolism><hepatic organ system><hepatic steatosis><hepatopathy><hepatosteatosis><infusions><insight><insulin resistant><insulin sensitivity><insulin tolerance><juvenile><juvenile human><ketogenesis><ketosis resistant diabetes><kids><lipid metabolism><liver disorder><liver metabolism><maturity onset diabetes><mitochondrial><mitochondrial metabolism><non-alcohol fatty liver disease><non-alcohol induced steatohepatitis><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic fatty liver disease><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><nonhuman primate models><novel><obesity intervention><obesity therapy><obesity treatment><oxidation><pyruvic carboxylase><resolutions><senior citizen><sex><social role><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><type 2 DM><type II DM><type two diabetes><weights><wt-loss><youngster>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

GERALD I SHULMAN

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$709,296

FY 2026

Project Title

Targeting hepatic mitochondrial oxidation to treat NAFLD, NASH and type 2 diabetes

Grant Number:

5R01DK135645-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/18/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD) are emerging as two of the most critical global health challenges of the 21st century. NAFLD is estimated to affect up to one third of the general population, and NAFLD is nearly universally present in patients with T2D, with 75-100%...

Research Terms

<0-11 years old><Address><Adolescent><Adolescent Youth><Adult-Onset Diabetes Mellitus><Affect><Agonist><Antidiabetic Hormone><Body Weight decreased><Child><Child Youth><Children (0-21)><Chronic><Cirrhosis><Clinical Trials><Data><Development><Diabetes Mellitus><Disease><Disorder><Elderly><Fats><Fatty Liver><Fatty acid glycerol esters><GLP-1><General Population><General Public><Glp-1><Glucagon><Glucagon Receptor><Gluconeogenesis><Glukagon><Grant><HG-Factor><Hepatic><Hepatic Disorder><Hepatic mitochondria><Human><Hyperglycemic-Glycogenolytic Factor><Individual><Infusion><Infusion procedures><Insulin Resistance><Ketosis-Resistant Diabetes Mellitus><Lipids><Liver><Liver Mitochondria><Liver Steatosis><Liver diseases><Maturity-Onset Diabetes Mellitus><Measures><Methods><Mitochondria><Modern Man><Muscle Mitochondria><NAFLD><NASH><NHP models><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Participant><Pathogenesis><Patients><Phase><Physiologic><Physiological><Pyruvate Carboxylase><Resolution><Rodent><Rodent Model><Rodentia><Rodents Mammals><Role><Sarcosomes><Science><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Steatohepatitis><T2 DM><T2D><T2DM><Testing><Tracer><Triacylglycerol><Triglycerides><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weight><Weight Loss><Weight Reduction><adult onset diabetes><advanced age><awake><body weight loss><cirrhotic><developmental><diabetes><fat metabolism><geriatric><global health><glucagon-like peptide 1><glucose biosynthesis><glucose metabolism><hepatic body system><hepatic disease><hepatic gluconeogenesis><hepatic metabolism><hepatic organ system><hepatic steatosis><hepatopathy><hepatosteatosis><infusions><insight><insulin resistant><insulin sensitivity><insulin tolerance><juvenile><juvenile human><ketogenesis><ketosis resistant diabetes><kids><lipid metabolism><liver disorder><liver metabolism><maturity onset diabetes><mitochondrial><mitochondrial metabolism><non-alcohol fatty liver disease><non-alcohol induced steatohepatitis><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic fatty liver disease><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><nonhuman primate models><novel><obesity intervention><obesity therapy><obesity treatment><oxidation><pyruvic carboxylase><resolutions><senior citizen><sex><social role><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><type 2 DM><type II DM><type two diabetes><weights><wt-loss><youngster>

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Ai Kubo

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$706,898

FY 2026

Project Title

Population-based Incidence, Time Trends, and Early Life Factors Associated with Type 2 Diabetes Among Asian American, Native Hawaiian, and Pacific Islander Adolescents and Young Adults

Grant Number:

5R01DK139116-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/28/2025

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The number of adolescents and young adults (AYA) with type 2 diabetes (T2D) has risen sharply in parallel with the obesity epidemic in the U.S. If current trends continue, the number of T2D cases among American youth is projected to increase more than seven-fold by 2060. Youth-onset T2D is debilitat...

Research Terms

<0-11 years old><10 year old><10 years of age><21+ years old><Adolescent and Young Adult><Adult><Adult Human><Adult-Onset Diabetes Mellitus><American><Asia><Asian><Asian Americans><BMI><BMI percentile><BMI z-score><Body mass index><California><Categories><Causality><Child><Child Youth><Childhood><Children (0-21)><Clinical><Clinical Data><Country><Data><Diagnosis><Early Diagnosis><Effectiveness><Electronic Health Record><Endocrine system><Endocrine/Metabolic Organ System><Epidemiology><Etiology><Exclusion><Future><Gestational Diabetes><Gestational Diabetes Mellitus><Goals><Guidelines><Health><Hormonal System><Human><Incidence><Individual><Intervention><Intervention Strategies><Ketosis-Resistant Diabetes Mellitus><Knowledge><Laboratories><Learning><Life><Link><Long-term cohort><Long-term cohort study><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal cohort study><Masks><Maturity-Onset Diabetes Mellitus><Metabolic><Metabolic/Endocrine Body System><Modern Man><NIDDM><Native Hawaiian and Other Pacific Islander><Native Hawaiian and Pacific Islander><Native Hawaiian or Other Pacific Islander><Native Hawaiian or Pacific Islander><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obesity Epidemic><Pacific Island individual><Pacific Island population><Pacific Islander><Persons><Population><Population Study><Pregnancy-Induced Diabetes><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Public Health Applications><Public Health Applications Research><Quetelet index><Reporting><Research><Research Resources><Resources><Risk><Risk Factors><Sampling><Slow-Onset Diabetes Mellitus><Source><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Teen><Teenagers><Temporal trend><Time trend><Trends over time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Youth><Youth 10-21><adiposity><adult onset diabetes><adult youth><adulthood><age 10><age 10 years><causation><co-morbid><co-morbidity><comorbidity><corpulence><demographics><design><designing><differences in health><disease causation><disease duration><disease length><early detection><early life exposure><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><endocrine gland/system><epidemiologic><epidemiological><experience><health care organization><health care service organization><health difference><high risk><illness length><improved><infancy><infantile><integrated care><integrated health care><integrated model of care><intervention design><ketosis resistant diabetes><kids><long-term study><longitudinal outcome studies><longitudinal research study><malleable risk><maturity onset diabetes><member><modifiable risk><mortality><pediatric><population based><population research study><population survey><population-based study><population-level study><pregnancy diabetes><research study><teen years><teenage><ten year old><ten years of age><therapy design><tool><treatment design><trend><type 2 DM><type II DM><type two diabetes><young adult><young adult age><young adulthood><youngster><youth age>

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Jung-Im Shin

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$699,322

FY 2026

Project Title

Challenges to Guideline-Recommended Diabetes Care in the United States

Grant Number:

5R01DK139324-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/17/2025

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Modern guidelines recommend novel, effective therapies such as sodium-glucose cotransporter 2 inhibitors (SGLT2i), glucagon-like peptide 1 receptor agonists (GLP1RA), and non-steroidal mineralocorticoid antagonists (MRA) in people with diabetes. However, there are significant gaps in adherence to gu...

Research Terms

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Barak Blum

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$688,170

FY 2026

Project Title

Regulation of spatial organization and cell-cell communication in the islet of Langerhans

Grant Number:

5R01DK121706-07

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2019

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

The most important determinant in whether a person will develop type 2 diabetes or gestational diabetes is whether their islets of Langerhans are able to compensate for the increase demand for insulin brought about by peripheral insulin resistance. In successful compensatory islet expansion (that ca...

Research Terms

<21+ years old><3-D><3-Dimensional><3D><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Alpha Cell><Antidiabetic Hormone><Architecture><Attention><B9 endocrine pancreas><Beta Cell><Body Tissues><Causality><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Death><Cell Differentiation><Cell Differentiation process><Cell Function><Cell Growth in Number><Cell Interaction><Cell Locomotion><Cell Maturation><Cell Migration><Cell Movement><Cell Multiplication><Cell Physiology><Cell Process><Cell Proliferation><Cell Signaling><Cell Surface Proteins><Cell-Extracellular Matrix><Cell-to-Cell Interaction><Cells><Cellular Function><Cellular Migration><Cellular Motility><Cellular Physiology><Cellular Process><Cellular Proliferation><Cessation of life><Compensation><D-Glucose><Data><Death><Defect><Development><Dextrose><Diabetes Mellitus><Down-Regulation><ECM><Embryo><Embryonic><Endocrine><Endocrine Pancreas><Engineering / Architecture><Epithelium><Etiology><Event><Extracellular Matrix><Failure><Funding><Future><Gene Transcription><Genes><Genetic Transcription><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucagon><Glucagon Cell><Glucagon Secreting Cell><Glucose><Glukagon><Goals><HG-Factor><Hormone secretion><Human><Humulin R><Hyperglycemic-Glycogenolytic Factor><Impairment><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intracellular Communication and Signaling><Islands of Langerhans><Islet Cell><Islets of Langerhans><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knockout><Life><Ligands><Maturity-Onset Diabetes Mellitus><Mediating><Mesenchymas><Mesenchyme><Mice><Mice Mammals><Modeling><Modern Man><Morphogenesis><Murine><Mus><NIDDM><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Pancreas><Pancreatic><Pancreatic Islets><Paracrine Communication><Paracrine Signaling><Pars endocrina pancreatis><Peripheral><Persons><Position><Positioning Attribute><Pregnancy><Pregnancy-Induced Diabetes><Publishing><RNA Expression><Receptor Protein><Recovery><Regular Insulin><Regulation><Relaxation><Rodent><Rodentia><Rodents Mammals><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stress><Stromal Cells><Subcellular Process><T2 DM><T2D><T2DM><Testing><Tissues><Transcription><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><adiposity><adult onset diabetes><adulthood><alpha-cell><biological signal transduction><blood glucose regulation><causation><cell motility><cellular differentiation><corpulence><developmental><diabetes><diabetic><diabetogenic><disease causation><global gene expression><global transcription profile><glucose control><glucose homeostasis><glucose regulation><hormonal regulation><hormonal secretion><hormone regulation><in vivo><insulin resistant><insulin tolerance><islet><ketosis resistant diabetes><maturity onset diabetes><morphogenetic process><necrocytosis><postnatal><pregnancy diabetes><prevent><preventing><receptor><response><restoration><social role><three dimensional><transcriptome><type 2 DM><type II DM><type two diabetes><α-cell><β-cell><β-cells><βCell>

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Brian Patrick Conlon

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$684,320

FY 2026

Project Title

Diabetes and Antibiotic Treatment Failure

Grant Number:

5R01AI173004-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

11/14/2022

End Date:

10/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Skin and soft tissue infection (SSTI) is a major complication in diabetic patients and Staphylococcus aureus is the most common causative organism. Antibiotics frequently fail to clear these infections, leading to chronic infection and progression to more severe infections such osteomyeliti...

Research Terms

<21+ years old><Acetic Acids><Acids><Address><Adult><Adult Human><Affect><Antibiotic Agents><Antibiotic Drugs><Antibiotic Resistance><Antibiotic Therapy><Antibiotic Treatment><Antibiotic susceptibility><Antibiotics><Automobile Driving><Bacteremia><Bacterial Antibiotic Resistance><Bioinformatics><Blood Glucose><Blood Sugar><Bone Infection><Carbon><Cell Body><Cells><Chronic><Clinical Data><Clinical Research><Clinical Study><Complication><Consumption><D-Glucose><DNA Damage><DNA Injury><DNA mutation><Data><Defect><Development><Dextrose><Diabetes Mellitus><Diabetic mouse><Environment><Evolution><Frequencies><Generalized Growth><Genetic><Genetic Change><Genetic defect><Genetic mutation><Genetics-Mutagenesis><Glucose><Glycolysis><Goals><Growth><Immune><Immune response><Immune system><Immunes><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><In Vitro><Individual><Infection><Infectious Skin Diseases><Inpatients><Intermediary Metabolism><Investigators><Lactic acid><Long-term infection><MRSA><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Methicillin Resistant S. Aureus><Mice><Mice Mammals><Microbial Biofilms><Miscellaneous Antibiotic><Modeling><Murine><Mus><Mutagenesis><Mutagenesis Molecular Biology><Mutation><Nutrient><Organism><Osteomyelitis><Oxidative Burst><Patients><Phagocytes><Phagocytic Cell><Phenocopy><Phenotype><Population><Position><Positioning Attribute><Predisposition><Production><Proliferating><Rapamune><Rapamycin><Relapse><Research Personnel><Researchers><Resistance><Resistance to antibiotics><Resistant to antibiotics><Respiratory Burst><Role><S aureus><S. aureus><S. aureus infection><Sepsis><Severities><Sirolimus><Soft Tissue Infections><Source><Staph aureus><Staph aureus infection><Staphylococcus aureus><Staphylococcus aureus infection><Susceptibility><Thesaurismosis><Time><Tissue Growth><Treatment Failure><Treatment outcome><Vancomycin><Vancomycin Resistance><Virulent><adulthood><amebocyte><antibiotic drug resistance><antibiotic resistant><antibiotic resistant bacteria><antibiotic tolerance><assault><bacteraemia><bacterial antibiotic resistant><bacterial bloodstream infection><bacterial disease treatment><bacterial infection in the bloodstream><bacterial infectious disease treatment><bacterial resistance to antibiotic><bactericidal><bactericide><biofilm><chronic infection><cutaneous infection><developmental><diabetes><diabetes mouse model><diabetic><diabetic patient><driving><experiment><experimental research><experimental study><experiments><fitness><genome mutation><host response><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive response><in vivo><infected skin><infected with S. aureus><infected with Staph aureus><infected with Staphylococcus aureus><leukocyte oxidative burst><living system><metabolism disorder><methicillin resistance Staphylococcus aureus><methicillin resistant Staphylococcus aureus><methicillin resistant strains of Staphylococcus aureus><mortality><multidisciplinary><ontogeny><pathogen><persistent infection><pressure><prevent><preventing><resistance strain><resistance to vancomycin><resistant><resistant strain><resistant to vancomycin><skin infection><social role><therapy failure><tolerance to antibiotics><tolerate antibiotics><vancomycin resistant>

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Lance R. Thurlow

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$684,320

FY 2026

Project Title

Diabetes and Antibiotic Treatment Failure

Grant Number:

5R01AI173004-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

11/14/2022

End Date:

10/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Skin and soft tissue infection (SSTI) is a major complication in diabetic patients and Staphylococcus aureus is the most common causative organism. Antibiotics frequently fail to clear these infections, leading to chronic infection and progression to more severe infections such osteomyeliti...

Research Terms

<21+ years old><Acetic Acids><Acids><Address><Adult><Adult Human><Affect><Antibiotic Agents><Antibiotic Drugs><Antibiotic Resistance><Antibiotic Therapy><Antibiotic Treatment><Antibiotic susceptibility><Antibiotics><Automobile Driving><Bacteremia><Bacterial Antibiotic Resistance><Bioinformatics><Blood Glucose><Blood Sugar><Bone Infection><Carbon><Cell Body><Cells><Chronic><Clinical Data><Clinical Research><Clinical Study><Complication><Consumption><D-Glucose><DNA Damage><DNA Injury><DNA mutation><Data><Defect><Development><Dextrose><Diabetes Mellitus><Diabetic mouse><Environment><Evolution><Frequencies><Generalized Growth><Genetic><Genetic Change><Genetic defect><Genetic mutation><Genetics-Mutagenesis><Glucose><Glycolysis><Goals><Growth><Immune><Immune response><Immune system><Immunes><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><In Vitro><Individual><Infection><Infectious Skin Diseases><Inpatients><Intermediary Metabolism><Investigators><Lactic acid><Long-term infection><MRSA><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Methicillin Resistant S. Aureus><Mice><Mice Mammals><Microbial Biofilms><Miscellaneous Antibiotic><Modeling><Murine><Mus><Mutagenesis><Mutagenesis Molecular Biology><Mutation><Nutrient><Organism><Osteomyelitis><Oxidative Burst><Patients><Phagocytes><Phagocytic Cell><Phenocopy><Phenotype><Population><Position><Positioning Attribute><Predisposition><Production><Proliferating><Rapamune><Rapamycin><Relapse><Research Personnel><Researchers><Resistance><Resistance to antibiotics><Resistant to antibiotics><Respiratory Burst><Role><S aureus><S. aureus><S. aureus infection><Sepsis><Severities><Sirolimus><Soft Tissue Infections><Source><Staph aureus><Staph aureus infection><Staphylococcus aureus><Staphylococcus aureus infection><Susceptibility><Thesaurismosis><Time><Tissue Growth><Treatment Failure><Treatment outcome><Vancomycin><Vancomycin Resistance><Virulent><adulthood><amebocyte><antibiotic drug resistance><antibiotic resistant><antibiotic resistant bacteria><antibiotic tolerance><assault><bacteraemia><bacterial antibiotic resistant><bacterial bloodstream infection><bacterial disease treatment><bacterial infection in the bloodstream><bacterial infectious disease treatment><bacterial resistance to antibiotic><bactericidal><bactericide><biofilm><chronic infection><cutaneous infection><developmental><diabetes><diabetes mouse model><diabetic><diabetic patient><driving><experiment><experimental research><experimental study><experiments><fitness><genome mutation><host response><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive response><in vivo><infected skin><infected with S. aureus><infected with Staph aureus><infected with Staphylococcus aureus><leukocyte oxidative burst><living system><metabolism disorder><methicillin resistance Staphylococcus aureus><methicillin resistant Staphylococcus aureus><methicillin resistant strains of Staphylococcus aureus><mortality><multidisciplinary><ontogeny><pathogen><persistent infection><pressure><prevent><preventing><resistance strain><resistance to vancomycin><resistant><resistant strain><resistant to vancomycin><skin infection><social role><therapy failure><tolerance to antibiotics><tolerate antibiotics><vancomycin resistant>

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Sara Jean Singer

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$679,371

FY 2026

Project Title

Implementing Scalable, PAtient-centered Team-based Care for Adults with Type 2 Diabetes and Health Disparities (iPATH)

Grant Number:

5R01MD017870-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/21/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT A collaborative network of research teams from Stanford, Harvard, The Ohio State University, and Impactivo, LLC propose practice-relevant research focused on diabetes care in federally qualified health centers (FQHCs). Some 37.3 million Americans have type 2 diabetes and FQHCs shoulder a hi...

Research Terms

<21+ years old><AHCPR><AHRQ><Acceleration><Address><Adopted><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Agency for Health Care Policy and Research><Agency for Healthcare Research and Quality><American><California><Caring><Case Study><Case-Base Studies><Chronic Care><Clinic><Clinical Data><Cluster randomization trial><Cluster randomized trial><Data><Data Analyses><Data Analysis><Data Collection><Data Reporting><Diabetes Mellitus><Effectiveness><Elements><Employment><Ensure><Environment><Environmental Factor><Environmental Risk Factor><Evaluation><Exploration, Preparation, Implementation, and Sustainability><Exploration, Preparation, Implementation, and Sustainment><Federally Qualified Health Center><Feedback><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Hemoglobin A(1)><High Prevalence><Hybrids><Interview><Investments><Ketosis-Resistant Diabetes Mellitus><Massachusetts><Maturity-Onset Diabetes Mellitus><Methodology><Methods><Modeling><NIDDM><NIH><National Committee for Quality Assurance><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutrition><Ohio><Outcome><Patient Care><Patient Care Delivery><Patients><Pilot Projects><Prevalence><Preventative care><Preventive care><Privatization><Process><Puerto Rico><Recommendation><Research><Science><Shoulder><Slow-Onset Diabetes Mellitus><Source><Stable Diabetes Mellitus><Standardization><T2 DM><T2D><T2DM><Technology><Testing><Transportation><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States Agency for Health Care Policy and Research><United States Agency for Healthcare Research and Quality><United States National Institutes of Health><Universities><acute care><adult onset diabetes><adulthood><care delivery><care for patients><care of patients><caring for patients><case report><data interpretation><data representation><data representations><data sharing><diabetes><diabetes control><diabetes mellitus control><disparity in health><environmental risk><experience><flexibility><flexible><geographic site><health care quality><health disparity><hemoglobin A1c><implementation determinants><implementation factors><implementation/effectiveness><improved><innovate><innovation><innovative><ketosis resistant diabetes><maturity onset diabetes><new approaches><novel><novel approaches><novel strategies><novel strategy><organizational readiness><pandemic><pandemic disease><patient centered><patient centered medical home><patient oriented><pilot study><post-pandemic><primary care medical home><public health relevance><remote care><remote health care><social factors><team-based care><tool><type 2 DM><type II DM><type two diabetes>

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Gang Hu

LSU PENNINGTON BIOMEDICAL RESEARCH CTR, BATON ROUGE, LA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$676,436

FY 2026

Project Title

Biomarker of Pancreatic B-cell Loss Predicting Progression to Type 2 Diabetes After Gestational Diabetes

Grant Number:

5R01DK132011-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT/PROJECT SUMMARY In this project, we prospectively examine the associations and predictive ability of unmethylated insulin gene (INS) DNA from 6-12 weeks postpartum and their subsequent changes several years later preceding the onset of type 2 diabetes (T2D) among two cohorts of women with p...

Research Terms

<21+ years old><Active Follow-up><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Amino Acids><Anthropometry><Apoptosis><Apoptosis Pathway><Asian><Assay><Autopsy><Behavioral><Beta Cell><Bioassay><Biological Assay><Biological Markers><Black><Black race><Blood Sample><Blood Serum><Blood specimen><Brittle Diabetes Mellitus><C-Peptide><Cell Body><Cell Death><Cell Function><Cell Physiology><Cell Process><Cells><Cellular Function><Cellular Physiology><Cellular Process><China><Chinese><Clinical><Collection><D-Glucose><DNA><DNA Methylation><Data><Defect><Deoxyribonucleic Acid><Dextrose><Diabetes Mellitus><Diagnosis><Diet><Disease><Disorder><Dysfunction><EHR system><Early treatment><European><Exercise><Fasting><Foundations><Functional disorder><Funding><Future><Genes><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Groups at risk><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><Heterogeneity><Hispanic><Human><Humulin R><Hyperglycemia><IDDM><In vivo analysis><Infant><Initiation Factors><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Laboratories><Lactation><Link><Lipids><Long-term cohort><Long-term prospective studies><Longitudinal cohort><Mainland China><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Meta-Analysis><Methodology><Methylation><Minority><Modern Man><Monitor><NIDDM><NIH><National Institutes of Health><Newly Diagnosed><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><OGTT><Obesity><Observational Study><Oral Glucose Tolerance Test><Pancreatic beta Cell><Pancreatic β-Cell><Participant><Pathogenesis><Patients><People at risk><Peptide Initiation Factors><Persons at risk><Physiopathology><Populations at Risk><Postpartum Period><Pregnancy><Pregnancy-Induced Diabetes><Pregnant Women><Prevention><Programmed Cell Death><Proinsulin><Prospective Studies><Prospective cohort><Regular Insulin><Reporting><Research><Research Design><Research Resources><Resources><Risk Factors><Sampling><Secretory Cell><Serum><Slow-Onset Diabetes Mellitus><Source><Stable Diabetes Mellitus><Structure of beta Cell of islet><Study Type><Subcellular Process><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Techniques><Testing><Therapeutic Intervention><Time><Translation Initiation Factor><Translational Initiation Factor><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Visit><Woman><Women's cohort><Women's study><active followup><adiposity><adult onset diabetes><adulthood><after gestational diabetes><aggressive therapy><aggressive treatment><aminoacid><attenuated insulin secretion><bio-markers><biobank><biologic marker><biomarker><biorepository><blunted insulin secretion><cell type><clinical practice><cohort><cohort in women><cohort investigation><cohort on women><cohort research><connecting peptide><corpulence><cost effective><ddPCR><decreased insulin release><decreased insulin secretion><defective insulin secretion><diabetes><diabetes risk><diagnosis among females><diagnosis among women><diagnosis in females><diagnosis in women><diagnosis within females><diagnosis within women><diets><diminished insulin release><diminished insulin secretion><droplet digital PCR><droplet digital Polymerase Chain Reaction><droplet-based digital PCR><early therapy><electronic health record system><expectant mother><expectant women><expecting mother><expecting women><fasted><fasting glucose><fasts><feeding><female cohort><female diagnosis><female study><follow up><follow-up><follow-up investigation><follow-up research><followed up><following gestational diabetes><followup><gestational diabetes history><hemoglobin A1c><hyperglycemic><impaired insulin release><impaired insulin secretion><improved><in vivo evaluation><in vivo testing><inadequate insulin release><inadequate insulin secretion><indexing><individuals who are pregnant><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><intergenerational><intervention therapy><investigate cohort><investigate follow-up><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lactating><lactational><longitudinal, prospective study><lowered insulin secretion><maturity onset diabetes><necrocytosis><necropsy><new marker><novel><novel biomarker><novel marker><observational cohort study><observational research study><observational survey><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><people who are pregnant><post-partum><postmortem><pregnancy diabetes><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><prospective><prospective research study><prospective survey><reduced insulin release><response><risk stratification><stratify risk><study among females><study among women><study cohort><study design><study follow-up><study in females><study in women><study on females><study on women><study within women><suppressed insulin release><suppressed insulin secretion><survey cohort><survey follow-up><those who are pregnant><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><women who are pregnant><women's diagnosis><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yeyi Zhu

LSU PENNINGTON BIOMEDICAL RESEARCH CTR, BATON ROUGE, LA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$676,436

FY 2026

Project Title

Biomarker of Pancreatic B-cell Loss Predicting Progression to Type 2 Diabetes After Gestational Diabetes

Grant Number:

5R01DK132011-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT/PROJECT SUMMARY In this project, we prospectively examine the associations and predictive ability of unmethylated insulin gene (INS) DNA from 6-12 weeks postpartum and their subsequent changes several years later preceding the onset of type 2 diabetes (T2D) among two cohorts of women with p...

Research Terms

<21+ years old><Active Follow-up><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Amino Acids><Anthropometry><Apoptosis><Apoptosis Pathway><Asian><Assay><Autopsy><Behavioral><Beta Cell><Bioassay><Biological Assay><Biological Markers><Black><Black race><Blood Sample><Blood Serum><Blood specimen><Brittle Diabetes Mellitus><C-Peptide><Cell Body><Cell Death><Cell Function><Cell Physiology><Cell Process><Cells><Cellular Function><Cellular Physiology><Cellular Process><China><Chinese><Clinical><Collection><D-Glucose><DNA><DNA Methylation><Data><Defect><Deoxyribonucleic Acid><Dextrose><Diabetes Mellitus><Diagnosis><Diet><Disease><Disorder><Dysfunction><EHR system><Early treatment><European><Exercise><Fasting><Foundations><Functional disorder><Funding><Future><Genes><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Groups at risk><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><Heterogeneity><Hispanic><Human><Humulin R><Hyperglycemia><IDDM><In vivo analysis><Infant><Initiation Factors><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Laboratories><Lactation><Link><Lipids><Long-term cohort><Long-term prospective studies><Longitudinal cohort><Mainland China><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Meta-Analysis><Methodology><Methylation><Minority><Modern Man><Monitor><NIDDM><NIH><National Institutes of Health><Newly Diagnosed><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><OGTT><Obesity><Observational Study><Oral Glucose Tolerance Test><Pancreatic beta Cell><Pancreatic β-Cell><Participant><Pathogenesis><Patients><People at risk><Peptide Initiation Factors><Persons at risk><Physiopathology><Populations at Risk><Postpartum Period><Pregnancy><Pregnancy-Induced Diabetes><Pregnant Women><Prevention><Programmed Cell Death><Proinsulin><Prospective Studies><Prospective cohort><Regular Insulin><Reporting><Research><Research Design><Research Resources><Resources><Risk Factors><Sampling><Secretory Cell><Serum><Slow-Onset Diabetes Mellitus><Source><Stable Diabetes Mellitus><Structure of beta Cell of islet><Study Type><Subcellular Process><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Techniques><Testing><Therapeutic Intervention><Time><Translation Initiation Factor><Translational Initiation Factor><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Visit><Woman><Women's cohort><Women's study><active followup><adiposity><adult onset diabetes><adulthood><after gestational diabetes><aggressive therapy><aggressive treatment><aminoacid><attenuated insulin secretion><bio-markers><biobank><biologic marker><biomarker><biorepository><blunted insulin secretion><cell type><clinical practice><cohort><cohort in women><cohort investigation><cohort on women><cohort research><connecting peptide><corpulence><cost effective><ddPCR><decreased insulin release><decreased insulin secretion><defective insulin secretion><diabetes><diabetes risk><diagnosis among females><diagnosis among women><diagnosis in females><diagnosis in women><diagnosis within females><diagnosis within women><diets><diminished insulin release><diminished insulin secretion><droplet digital PCR><droplet digital Polymerase Chain Reaction><droplet-based digital PCR><early therapy><electronic health record system><expectant mother><expectant women><expecting mother><expecting women><fasted><fasting glucose><fasts><feeding><female cohort><female diagnosis><female study><follow up><follow-up><follow-up investigation><follow-up research><followed up><following gestational diabetes><followup><gestational diabetes history><hemoglobin A1c><hyperglycemic><impaired insulin release><impaired insulin secretion><improved><in vivo evaluation><in vivo testing><inadequate insulin release><inadequate insulin secretion><indexing><individuals who are pregnant><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin secretion><insulin sensitivity><insulin tolerance><intergenerational><intervention therapy><investigate cohort><investigate follow-up><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lactating><lactational><longitudinal, prospective study><lowered insulin secretion><maturity onset diabetes><necrocytosis><necropsy><new marker><novel><novel biomarker><novel marker><observational cohort study><observational research study><observational survey><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><people who are pregnant><post-partum><postmortem><pregnancy diabetes><pregnant females><pregnant mothers><pregnant people><pregnant populations><prevent><preventing><prospective><prospective research study><prospective survey><reduced insulin release><response><risk stratification><stratify risk><study among females><study among women><study cohort><study design><study follow-up><study in females><study in women><study on females><study on women><study within women><suppressed insulin release><suppressed insulin secretion><survey cohort><survey follow-up><those who are pregnant><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><women who are pregnant><women's diagnosis><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

CLAYTON E MATHEWS

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$672,933

FY 2026

Project Title

Discovery and Roles of In Situ Islet Neoantigens in Human Type 1 Diabetes

Grant Number:

5R01DK135081-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract: Type 1 diabetes (T1D) is a complex autoimmune disease resulting from immune-mediated destruction of pancreatic beta-cells within the islets of Langerhans. Unfortunately, gaps in our understanding exist on the exact mechanisms triggering the initial break of immune tolerance...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DAVID A OSTROV

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$672,933

FY 2026

Project Title

Discovery and Roles of In Situ Islet Neoantigens in Human Type 1 Diabetes

Grant Number:

5R01DK135081-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract: Type 1 diabetes (T1D) is a complex autoimmune disease resulting from immune-mediated destruction of pancreatic beta-cells within the islets of Langerhans. Unfortunately, gaps in our understanding exist on the exact mechanisms triggering the initial break of immune tolerance...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Wei-Jun Qian

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$672,933

FY 2026

Project Title

Discovery and Roles of In Situ Islet Neoantigens in Human Type 1 Diabetes

Grant Number:

5R01DK135081-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract: Type 1 diabetes (T1D) is a complex autoimmune disease resulting from immune-mediated destruction of pancreatic beta-cells within the islets of Langerhans. Unfortunately, gaps in our understanding exist on the exact mechanisms triggering the initial break of immune tolerance...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Monique Marie Hedderson

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$671,519

FY 2026

Project Title

Comparing the effects of pharmacological treatment for gestational diabetes on long-term maternal and child health outcomes

Grant Number:

5R01DK138135-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/20/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Gestational diabetes mellitus (GDM) is among the most common complications of pregnancy and it increases the risk of perinatal complications and long-term sequelae for both the mother (subsequent diabetes) and the exposed child (obesity). Up to 50% of women with GDM require the addition of ...

Research Terms

<0-11 years old><10 year old><10 years of age><ACOG><Active Follow-up><Affect><American><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><Beta Cell><California><Cardiovascular Diseases><Cells Placenta-Tissue><Child><Child Youth><Children (0-21)><Clinical><Clinical Data><Cohort Studies><Data><Demography><Diabetes Mellitus><Diagnosis><Diet therapy><Dimethylbiguanidine><Dimethylguanylguanidine><Dose><Drug Kinetics><Drug Therapy><Drugs><Electronic Health Record><Exclusion Criteria><Exposure to><Fetal Tissues><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glibenclamide><Glybenclamide><Glyburide><Growth><Guidelines><Health><Humulin R><Hypertension><Hypoglycemic Agents><Hypoglycemic Drugs><Hypoglycemics><Incidence><Infant><Insulin><Insulin Cell><Insulin Secreting Cell><Intention><Knowledge><Long-Term Effects><Long-term Follow-up><Long-term cohort study><Longitudinal cohort study><Machine Learning><Maternal and Child Health><Medical><Medication><Metabolic><Metformin><Methodology><Methods><Micronase><Modernization><Mothers><N,N-dimethyl-imidodicarbonimidic diamide><Neonatal Hypoglycemia><Normal Placentoma><Novolin R><Nutritional Support><Obesity><Observational Study><Oral><Outcome><Patients><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Placenta><Placenta Embryonic Tissue><Placentome><Population><Population Heterogeneity><Population Research><Population-based research><Population-level research><Postpartum Period><Pregnancy><Pregnancy Complications><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Preventative strategy><Prevention strategy><Preventive strategy><Property><Protocol><Protocols documentation><Randomized, Controlled Trials><Recommendation><Regimen><Regular Insulin><Risk><Risk Factors><Risk Reduction><Safety><Sample Size><Selection Bias><Series><Severities><Site><Specific qualifier value><Specified><Statistical Methods><Time><Tissue Growth><Treatment Protocols><Treatment Regimen><Treatment Schedule><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><active comparator><active comparison control><active followup><adiposity><after pregnancy><age 10><age 10 years><antihyperglycemic><cardiometabolic><cardiometabolism><cardiovascular disorder><care as usual><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical practice><cohort research study><cohort survey><complications during pregnancy><corpulence><cost><data collected in real world><diabetes><diabetes risk><diagnosis among females><diagnosis among women><diagnosis in females><diagnosis in women><diagnosis within females><diagnosis within women><dietary therapy><diverse populations><drug intervention><drug treatment><drug/agent><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><exhaustion><expectant mother><expectant women><expecting mother><expecting women><female diagnosis><fetus tissue><follow up><follow-up><followed up><followup><glycemic control><head-to-head analysis><head-to-head comparison><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><individuals who are pregnant><infantile hypoglycemia><investigate population><kids><long-term followup><long-term sequelae><machine based learning><maternal diabetes><maternal risk><member><nutritional care><nutritional therapy><obese children><obesity during childhood><obesity in children><obesity risk><observational research study><observational survey><ontogeny><optimal therapies><optimal treatments><overweight child><overweight childhood><pediatric obesity><people who are pregnant><perinatal complications><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><population diversity><population investigation><population level investigation><population specific research><post pregnancy><post-partum><pragmatic randomized trial><pregnancy diabetes><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prepregnancy obesity><preterm delivery><randomized control trial><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk for obesity><risk of obesity><risk-reducing><statistic methods><studies of populations><study of the population><study population><survey population><ten year old><ten years of age><those who are pregnant><treatment as usual><treatment strategy><trial comparing><usual care><women who are pregnant><women's diagnosis><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Romain Neugebauer

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$671,519

FY 2026

Project Title

Comparing the effects of pharmacological treatment for gestational diabetes on long-term maternal and child health outcomes

Grant Number:

5R01DK138135-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/20/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Gestational diabetes mellitus (GDM) is among the most common complications of pregnancy and it increases the risk of perinatal complications and long-term sequelae for both the mother (subsequent diabetes) and the exposed child (obesity). Up to 50% of women with GDM require the addition of ...

Research Terms

<0-11 years old><10 year old><10 years of age><ACOG><Active Follow-up><Affect><American><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><Beta Cell><California><Cardiovascular Diseases><Cells Placenta-Tissue><Child><Child Youth><Children (0-21)><Clinical><Clinical Data><Cohort Studies><Data><Demography><Diabetes Mellitus><Diagnosis><Diet therapy><Dimethylbiguanidine><Dimethylguanylguanidine><Dose><Drug Kinetics><Drug Therapy><Drugs><Electronic Health Record><Exclusion Criteria><Exposure to><Fetal Tissues><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glibenclamide><Glybenclamide><Glyburide><Growth><Guidelines><Health><Humulin R><Hypertension><Hypoglycemic Agents><Hypoglycemic Drugs><Hypoglycemics><Incidence><Infant><Insulin><Insulin Cell><Insulin Secreting Cell><Intention><Knowledge><Long-Term Effects><Long-term Follow-up><Long-term cohort study><Longitudinal cohort study><Machine Learning><Maternal and Child Health><Medical><Medication><Metabolic><Metformin><Methodology><Methods><Micronase><Modernization><Mothers><N,N-dimethyl-imidodicarbonimidic diamide><Neonatal Hypoglycemia><Normal Placentoma><Novolin R><Nutritional Support><Obesity><Observational Study><Oral><Outcome><Patients><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Placenta><Placenta Embryonic Tissue><Placentome><Population><Population Heterogeneity><Population Research><Population-based research><Population-level research><Postpartum Period><Pregnancy><Pregnancy Complications><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Preventative strategy><Prevention strategy><Preventive strategy><Property><Protocol><Protocols documentation><Randomized, Controlled Trials><Recommendation><Regimen><Regular Insulin><Risk><Risk Factors><Risk Reduction><Safety><Sample Size><Selection Bias><Series><Severities><Site><Specific qualifier value><Specified><Statistical Methods><Time><Tissue Growth><Treatment Protocols><Treatment Regimen><Treatment Schedule><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><active comparator><active comparison control><active followup><adiposity><after pregnancy><age 10><age 10 years><antihyperglycemic><cardiometabolic><cardiometabolism><cardiovascular disorder><care as usual><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical practice><cohort research study><cohort survey><complications during pregnancy><corpulence><cost><data collected in real world><diabetes><diabetes risk><diagnosis among females><diagnosis among women><diagnosis in females><diagnosis in women><diagnosis within females><diagnosis within women><dietary therapy><diverse populations><drug intervention><drug treatment><drug/agent><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><exhaustion><expectant mother><expectant women><expecting mother><expecting women><female diagnosis><fetus tissue><follow up><follow-up><followed up><followup><glycemic control><head-to-head analysis><head-to-head comparison><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><individuals who are pregnant><infantile hypoglycemia><investigate population><kids><long-term followup><long-term sequelae><machine based learning><maternal diabetes><maternal risk><member><nutritional care><nutritional therapy><obese children><obesity during childhood><obesity in children><obesity risk><observational research study><observational survey><ontogeny><optimal therapies><optimal treatments><overweight child><overweight childhood><pediatric obesity><people who are pregnant><perinatal complications><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><population diversity><population investigation><population level investigation><population specific research><post pregnancy><post-partum><pragmatic randomized trial><pregnancy diabetes><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prepregnancy obesity><preterm delivery><randomized control trial><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk for obesity><risk of obesity><risk-reducing><statistic methods><studies of populations><study of the population><study population><survey population><ten year old><ten years of age><those who are pregnant><treatment as usual><treatment strategy><trial comparing><usual care><women who are pregnant><women's diagnosis><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ANNY H XIANG

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$671,519

FY 2026

Project Title

Comparing the effects of pharmacological treatment for gestational diabetes on long-term maternal and child health outcomes

Grant Number:

5R01DK138135-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/20/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Gestational diabetes mellitus (GDM) is among the most common complications of pregnancy and it increases the risk of perinatal complications and long-term sequelae for both the mother (subsequent diabetes) and the exposed child (obesity). Up to 50% of women with GDM require the addition of ...

Research Terms

<0-11 years old><10 year old><10 years of age><ACOG><Active Follow-up><Affect><American><American College of Obstetricians and Gynecologists><American College of Obstetricians and Gynecology><American College of Obstetrics and Gynecologists><American College of Obstetrics and Gynecology><Beta Cell><California><Cardiovascular Diseases><Cells Placenta-Tissue><Child><Child Youth><Children (0-21)><Clinical><Clinical Data><Cohort Studies><Data><Demography><Diabetes Mellitus><Diagnosis><Diet therapy><Dimethylbiguanidine><Dimethylguanylguanidine><Dose><Drug Kinetics><Drug Therapy><Drugs><Electronic Health Record><Exclusion Criteria><Exposure to><Fetal Tissues><Generalized Growth><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glibenclamide><Glybenclamide><Glyburide><Growth><Guidelines><Health><Humulin R><Hypertension><Hypoglycemic Agents><Hypoglycemic Drugs><Hypoglycemics><Incidence><Infant><Insulin><Insulin Cell><Insulin Secreting Cell><Intention><Knowledge><Long-Term Effects><Long-term Follow-up><Long-term cohort study><Longitudinal cohort study><Machine Learning><Maternal and Child Health><Medical><Medication><Metabolic><Metformin><Methodology><Methods><Micronase><Modernization><Mothers><N,N-dimethyl-imidodicarbonimidic diamide><Neonatal Hypoglycemia><Normal Placentoma><Novolin R><Nutritional Support><Obesity><Observational Study><Oral><Outcome><Patients><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Placenta><Placenta Embryonic Tissue><Placentome><Population><Population Heterogeneity><Population Research><Population-based research><Population-level research><Postpartum Period><Pregnancy><Pregnancy Complications><Pregnancy-Induced Diabetes><Pregnant Women><Premature Birth><Prematurely delivering><Preterm Birth><Preventative strategy><Prevention strategy><Preventive strategy><Property><Protocol><Protocols documentation><Randomized, Controlled Trials><Recommendation><Regimen><Regular Insulin><Risk><Risk Factors><Risk Reduction><Safety><Sample Size><Selection Bias><Series><Severities><Site><Specific qualifier value><Specified><Statistical Methods><Time><Tissue Growth><Treatment Protocols><Treatment Regimen><Treatment Schedule><Variant><Variation><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><active comparator><active comparison control><active followup><adiposity><after pregnancy><age 10><age 10 years><antihyperglycemic><cardiometabolic><cardiometabolism><cardiovascular disorder><care as usual><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical practice><cohort research study><cohort survey><complications during pregnancy><corpulence><cost><data collected in real world><diabetes><diabetes risk><diagnosis among females><diagnosis among women><diagnosis in females><diagnosis in women><diagnosis within females><diagnosis within women><dietary therapy><diverse populations><drug intervention><drug treatment><drug/agent><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><exhaustion><expectant mother><expectant women><expecting mother><expecting women><female diagnosis><fetus tissue><follow up><follow-up><followed up><followup><glycemic control><head-to-head analysis><head-to-head comparison><heterogeneous population><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><individuals who are pregnant><infantile hypoglycemia><investigate population><kids><long-term followup><long-term sequelae><machine based learning><maternal diabetes><maternal risk><member><nutritional care><nutritional therapy><obese children><obesity during childhood><obesity in children><obesity risk><observational research study><observational survey><ontogeny><optimal therapies><optimal treatments><overweight child><overweight childhood><pediatric obesity><people who are pregnant><perinatal complications><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><population diversity><population investigation><population level investigation><population specific research><post pregnancy><post-partum><pragmatic randomized trial><pregnancy diabetes><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature childbirth><premature delivery><prepregnancy obesity><preterm delivery><randomized control trial><real world data><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk for obesity><risk of obesity><risk-reducing><statistic methods><studies of populations><study of the population><study population><survey population><ten year old><ten years of age><those who are pregnant><treatment as usual><treatment strategy><trial comparing><usual care><women who are pregnant><women's diagnosis><youngster><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Akos A Gerencser

BUCK INSTITUTE FOR RESEARCH ON AGING, NOVATO, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$670,313

FY 2026

Project Title

Novel components of mitochondrial regulation of insulin secretion in type 2 diabetes

Grant Number:

5R01DK135807-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY The success of preventive and supportive approaches in type 2 diabetes mellitus (T2D) depends on the spontaneous recovery of β-cell function. A central component of β-cell function, glucose metabolism, is impaired in T2D. Its causes, and how this impairment might lead to functional f...

Research Terms

View Full Project Details on NIH Reporter

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Joana Almaca

UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, CORAL GABLES, FL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$662,173

FY 2026

Project Title

Loss of insulin signaling across functional pancreas compartments as a major pathogenic mechanism underlying diabetic exocrine pancreatopathy

Grant Number:

5R01DK138471-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/12/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY ABSTRACT The exocrine pancreas of patients with type 1 diabetes is smaller than the pancreas of healthy subjects and shows histological anomalies such as fibrosis, fatty degeneration, inflammatory cell infiltration and atherosclerosis. The histological features associated with diabet...

Research Terms

<21+ years old><ASCVD><Acinar Cell><Aciner Cells><Acute><Address><Adult><Adult Human><Adventitial Cell><Affect><Anatomic Sites><Anatomic structures><Anatomy><Atherosclerosis><Atherosclerotic Cardiovascular Disease><B9 endocrine pancreas><Beta Cell><Blood Vessels><Blood flow><Body Tissues><Brittle Diabetes Mellitus><Causality><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chronic><Data><Dedications><Deterioration><Development><Diabetes Mellitus><Disease><Disorder><Dysfunction><Endocrine><Endocrine Pancreas><Endothelial Cells><Enteral><Enteric><Etiology><Exocrine pancreas><Fibrosis><Functional disorder><Gene Expression><Genetic><Goals><Histologic><Histologically><Human><Humulin R><IDDM><Impairment><Individual><Infiltration><Inflammation><Inflammatory><Insulin><Insulin Cell><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin Secreting Cell><Insulin Signaling Pathway><Insulin-Dependent Diabetes Mellitus><Insulin-Dependent Tyrosine Protein Kinase><Intracellular Communication and Signaling><Islands of Langerhans><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><KO mice><Ketosis-Prone Diabetes Mellitus><Knock-out Mice><Knockout Mice><Knowledge><Measures><Mice><Mice Mammals><Mission><Modeling><Modern Man><Murine><Mus><NIH><National Institutes of Health><Nerve Cells><Nerve Impulse Transmission><Nerve Transmission><Nerve Unit><Nesidioblasts><Neural Cell><Neurocyte><Neuronal Transmission><Neurons><Novolin R><Null Mouse><Organ Donor><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathogenicity><Pathologic><Patients><Pericapillary Cell><Pericytes><Perivascular Cell><Persons><Physiopathology><Prevalence><Regular Insulin><Regulation><Regulatory Element><Research><Research Specimen><Role><Rouget Cells><Secretory Cell><Signal Transduction><Signal Transduction Systems><Signaling><Site><Slice><Specimen><Subcellular Process><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Testing><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States National Institutes of Health><adulthood><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><autoimmune attack><autoimmune destruction><autoimmune pathogenesis><axon signaling><axon-glial signaling><axonal signaling><biological signal transduction><blood glucose regulation><causation><cholinergic><chronic pancreatitis><develop therapy><developmental><diabetes><diabetic><disease causation><exocrine pancreatic><glia signaling><glial signaling><glucose control><glucose homeostasis><glucose regulation><in vivo><insight><insulin dependent diabetes><insulin dependent type 1><insulin secretion><insulin signaling><intervention development><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><mouse model><murine model><nerve signaling><neural><neural signaling><neuronal><neuronal signaling><neurotransmission><nutrient absorption><paracrine><pathophysiology><recurrent pancreatitis><response><social role><therapy development><tool><treatment development><type I diabetes><type one diabetes><vascular><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

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Ernesto Bernal-Mizrachi

UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, CORAL GABLES, FL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$662,173

FY 2026

Project Title

Loss of insulin signaling across functional pancreas compartments as a major pathogenic mechanism underlying diabetic exocrine pancreatopathy

Grant Number:

5R01DK138471-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/12/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY ABSTRACT The exocrine pancreas of patients with type 1 diabetes is smaller than the pancreas of healthy subjects and shows histological anomalies such as fibrosis, fatty degeneration, inflammatory cell infiltration and atherosclerosis. The histological features associated with diabet...

Research Terms

<21+ years old><ASCVD><Acinar Cell><Aciner Cells><Acute><Address><Adult><Adult Human><Adventitial Cell><Affect><Anatomic Sites><Anatomic structures><Anatomy><Atherosclerosis><Atherosclerotic Cardiovascular Disease><B9 endocrine pancreas><Beta Cell><Blood Vessels><Blood flow><Body Tissues><Brittle Diabetes Mellitus><Causality><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chronic><Data><Dedications><Deterioration><Development><Diabetes Mellitus><Disease><Disorder><Dysfunction><Endocrine><Endocrine Pancreas><Endothelial Cells><Enteral><Enteric><Etiology><Exocrine pancreas><Fibrosis><Functional disorder><Gene Expression><Genetic><Goals><Histologic><Histologically><Human><Humulin R><IDDM><Impairment><Individual><Infiltration><Inflammation><Inflammatory><Insulin><Insulin Cell><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin Secreting Cell><Insulin Signaling Pathway><Insulin-Dependent Diabetes Mellitus><Insulin-Dependent Tyrosine Protein Kinase><Intracellular Communication and Signaling><Islands of Langerhans><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><KO mice><Ketosis-Prone Diabetes Mellitus><Knock-out Mice><Knockout Mice><Knowledge><Measures><Mice><Mice Mammals><Mission><Modeling><Modern Man><Murine><Mus><NIH><National Institutes of Health><Nerve Cells><Nerve Impulse Transmission><Nerve Transmission><Nerve Unit><Nesidioblasts><Neural Cell><Neurocyte><Neuronal Transmission><Neurons><Novolin R><Null Mouse><Organ Donor><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathogenicity><Pathologic><Patients><Pericapillary Cell><Pericytes><Perivascular Cell><Persons><Physiopathology><Prevalence><Regular Insulin><Regulation><Regulatory Element><Research><Research Specimen><Role><Rouget Cells><Secretory Cell><Signal Transduction><Signal Transduction Systems><Signaling><Site><Slice><Specimen><Subcellular Process><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Testing><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States National Institutes of Health><adulthood><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><autoimmune attack><autoimmune destruction><autoimmune pathogenesis><axon signaling><axon-glial signaling><axonal signaling><biological signal transduction><blood glucose regulation><causation><cholinergic><chronic pancreatitis><develop therapy><developmental><diabetes><diabetic><disease causation><exocrine pancreatic><glia signaling><glial signaling><glucose control><glucose homeostasis><glucose regulation><in vivo><insight><insulin dependent diabetes><insulin dependent type 1><insulin secretion><insulin signaling><intervention development><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><mouse model><murine model><nerve signaling><neural><neural signaling><neuronal><neuronal signaling><neurotransmission><nutrient absorption><paracrine><pathophysiology><recurrent pancreatitis><response><social role><therapy development><tool><treatment development><type I diabetes><type one diabetes><vascular><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alejandro Caicedo

UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, CORAL GABLES, FL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$662,173

FY 2026

Project Title

Loss of insulin signaling across functional pancreas compartments as a major pathogenic mechanism underlying diabetic exocrine pancreatopathy

Grant Number:

5R01DK138471-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/12/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY ABSTRACT The exocrine pancreas of patients with type 1 diabetes is smaller than the pancreas of healthy subjects and shows histological anomalies such as fibrosis, fatty degeneration, inflammatory cell infiltration and atherosclerosis. The histological features associated with diabet...

Research Terms

<21+ years old><ASCVD><Acinar Cell><Aciner Cells><Acute><Address><Adult><Adult Human><Adventitial Cell><Affect><Anatomic Sites><Anatomic structures><Anatomy><Atherosclerosis><Atherosclerotic Cardiovascular Disease><B9 endocrine pancreas><Beta Cell><Blood Vessels><Blood flow><Body Tissues><Brittle Diabetes Mellitus><Causality><Cell Body><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chronic><Data><Dedications><Deterioration><Development><Diabetes Mellitus><Disease><Disorder><Dysfunction><Endocrine><Endocrine Pancreas><Endothelial Cells><Enteral><Enteric><Etiology><Exocrine pancreas><Fibrosis><Functional disorder><Gene Expression><Genetic><Goals><Histologic><Histologically><Human><Humulin R><IDDM><Impairment><Individual><Infiltration><Inflammation><Inflammatory><Insulin><Insulin Cell><Insulin Receptor><Insulin Receptor Protein-Tyrosine Kinase><Insulin Secreting Cell><Insulin Signaling Pathway><Insulin-Dependent Diabetes Mellitus><Insulin-Dependent Tyrosine Protein Kinase><Intracellular Communication and Signaling><Islands of Langerhans><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><KO mice><Ketosis-Prone Diabetes Mellitus><Knock-out Mice><Knockout Mice><Knowledge><Measures><Mice><Mice Mammals><Mission><Modeling><Modern Man><Murine><Mus><NIH><National Institutes of Health><Nerve Cells><Nerve Impulse Transmission><Nerve Transmission><Nerve Unit><Nesidioblasts><Neural Cell><Neurocyte><Neuronal Transmission><Neurons><Novolin R><Null Mouse><Organ Donor><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathogenicity><Pathologic><Patients><Pericapillary Cell><Pericytes><Perivascular Cell><Persons><Physiopathology><Prevalence><Regular Insulin><Regulation><Regulatory Element><Research><Research Specimen><Role><Rouget Cells><Secretory Cell><Signal Transduction><Signal Transduction Systems><Signaling><Site><Slice><Specimen><Subcellular Process><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Testing><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States National Institutes of Health><adulthood><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><autoimmune attack><autoimmune destruction><autoimmune pathogenesis><axon signaling><axon-glial signaling><axonal signaling><biological signal transduction><blood glucose regulation><causation><cholinergic><chronic pancreatitis><develop therapy><developmental><diabetes><diabetic><disease causation><exocrine pancreatic><glia signaling><glial signaling><glucose control><glucose homeostasis><glucose regulation><in vivo><insight><insulin dependent diabetes><insulin dependent type 1><insulin secretion><insulin signaling><intervention development><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><mouse model><murine model><nerve signaling><neural><neural signaling><neuronal><neuronal signaling><neurotransmission><nutrient absorption><paracrine><pathophysiology><recurrent pancreatitis><response><social role><therapy development><tool><treatment development><type I diabetes><type one diabetes><vascular><β-cell><β-cells><βCell>

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RICHARD W GRANT

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$656,295

FY 2026

Project Title

Pragmatic Clinical Trial of Continuous Glucose Monitoring-based Interventions for Safe Insulin Prescribing in High-Risk Older Patients with Type 2 Diabetes

Grant Number:

5R01DK134446-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Hypoglycemia is a common and preventable complication of insulin treatment in type 2 diabetes (T2D) that increases dramatically with age. In older adults (age ≥ 75), hypoglycemia accounts for 20% of all Emergency Department admissions for adverse drug events (primarily due to insulin). Hypo...

Research Terms

<21+ years old><Accident and Emergency department><Address><Admission><Admission activity><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Adverse drug event><Age><Algorithms><Amentia><American><Blood Glucose Self-Monitoring><Blood Sugar Self-Monitoring><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Caring><Cessation of life><Classification><Clinical><Clinical Trials Design><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complication><Continuous Glucose Monitor><Coupled><D-Glucose><Death><Dementia><Dextrose><Diabetes Mellitus><Diet><Disturbance in cognition><Dose><Drugs><ED visit><ER visit><Education><Education and Training><Educational aspects><Electronic Health Record><Emergency Department><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room><Emergency room visit><Ethnic Origin><Ethnicity><Event><Fear><Fingers><Fracture><Fright><Funding><Future><Glucose><Goals><Health Status><Health system><Heart Vascular><Heterogeneity><Home Blood Glucose Monitoring><Hospital Admission><Hospitalization><Human Resources><Humulin R><Hyperglycemia><Hypoglycemia><Iatrogenesis><Impaired cognition><Incidence><Injections><Insulin><Insurance Carriers><Insurers><Intervention><Intervention Strategies><Investments><Ketosis-Resistant Diabetes Mellitus><Level of Health><Manpower><Maturity-Onset Diabetes Mellitus><Measures><Medication><Modeling><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Observational Study><Patient Education><Patient Instruction><Patient Self-Report><Patient Training><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Persons><Pharmaceutical Preparations><Pharmacists><Physical activity><Population><Pragmatic clinical trial><QOL><Quality of life><Race><Races><Randomization trial><Randomized><Regimen><Regular Insulin><Research Proposals><Risk><Risk Factors><Safety><Self Efficacy><Self-Report><Slow-Onset Diabetes Mellitus><Specific qualifier value><Specified><Stable Diabetes Mellitus><Symptoms><System><Systematics><T2 DM><T2D><T2DM><Testing><Time><Training and Education><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Validation><Veterans><active comparator><active comparison control><adult onset diabetes><adulthood><ages><arm><bone fracture><care as usual><care delivery><circulatory system><clinical effect><co-morbid><co-morbidity><cognitive dysfunction><cognitive loss><comorbidity><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><dementia risk><design><designing><determine efficacy><diabetes><diabetes distress><diabetes-related distress><diabetes-specific distress><diets><dissemination strategy><distress related to diabetes><distress specific to diabetes><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><elderly patient><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evaluate efficacy><examine efficacy><falls><glucometer><glucose meter><glucose monitor><glycemic control><health level><health literacy><high risk><hyperglycemic><hypoglycemia unawareness><hypoglycemic><hypoglycemic episodes><iatrogenic><iatrogenically><iatrogenicity><improved><innovate><innovation><innovative><integrated care><integrated health care><integrated model of care><intervention arm><intervention program><ketosis resistant diabetes><maturity onset diabetes><medicare cost><medicare expenditures><medicare payments><medicare reimbursement><medicare spending><mortality><novel><observational research study><observational survey><older adult><older adulthood><older patient><participant enrollment><patient centered><patient enrollment><patient oriented><patient oriented outcomes><patient safety><personnel><pragmatic effectiveness trial><pragmatic trial><prevent><preventing><programs><racial><racial background><racial origin><randomisation><randomization><randomized trial><randomized, clinical trials><randomly assigned><risk factor for dementia><risk for dementia><risk prediction algorithm><risk prediction model><statistics><treatment arm><treatment as usual><treatment effect><trend><trial design><type 2 DM><type II DM><type two diabetes><usual care><validations>

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Maria Sara Remedi

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$625,889

FY 2026

Project Title

Beta cell exhaustion and glucotoxicity in Diabetes

Grant Number:

5R01DK123163-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2020

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project summary Diabetes is characterized by progressive loss or dysfunction of pancreatic insulin- producing β-cells. Previous efforts demonstrated loss of β-cell identity, rather than cell death, as a primary contributor in loss of functional β-cell mass in diabetes progression. Strikingly, this p...

Research Terms

<Adult-Onset Diabetes Mellitus><Animal Model><Animal Models and Related Studies><Animals><Anti-diabetic Agents><Anti-diabetic Drugs><Autophagocytosis><Beta Cell><Blood Glucose><Blood Sugar><Cell Body><Cell Death><Cell Function><Cell Physiology><Cell Process><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular injury><Clinical Treatment><Diabetes Mellitus><Diabetes mellitus syndrome in newborn infant><Dietary Intervention><Drug Therapy><Dysfunction><ER stress><Enzyme Gene><Enzymes><Failure><Functional disorder><Gene Expression><Gene Proteins><Genetic><Glucokinase><Glucose Binding Protein><Glucose Transport Protein><Glucose Transporter><Glycolysis><Goals><Heterozygote><Human><Humulin R><Hyperglycemia><Impairment><Individual><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intermediary Metabolism><Intermittent fasting><Intervention><Ketosis-Resistant Diabetes Mellitus><Link><Maturity-Onset Diabetes Mellitus><Metabolic><Metabolic Processes><Metabolism><Modern Man><Molecular><NIDDM><Na element><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nutrition Interventions><Nutritional Interventions><Obesity><Oxidative Stress><Pancreas><Pancreatic><Pancreatic beta Cell><Pancreatic β-Cell><Pharmacological Treatment><Pharmacotherapy><Physiopathology><Play><Process><Proinsulin><Protein Gene Products><Regular Insulin><Role><Slow-Onset Diabetes Mellitus><Sodium><Stable Diabetes Mellitus><Structure of beta Cell of islet><Subcellular Process><T2 DM><T2D><T2DM><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Work><World Health><adiposity><adult onset diabetes><anti-diabetic><autophagy><blood glucose regulation><cell damage><cell injury><cellular damage><clinical intervention><clinical therapy><corpulence><damage to cells><diabetes><diet intervention><disparate effect><disparate impact><disparate result><drug intervention><drug treatment><endoplasmic reticulum stress><exhaustion><experiment><experimental research><experimental study><experiments><functional loss><functional restoration><glucose control><glucose homeostasis><glucose metabolism><glucose regulation><heterozygosity><human disease><hyperglycemic><improved><in vivo><inequitable effect><inequitable impact><inequitable outcome><inhibitor><injury to cells><insight><insulin resistant><insulin secretion><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><model of animal><mouse model><murine model><necrocytosis><neonatal diabetes><neonatal diabetes mellitus><new approaches><novel><novel approaches><novel strategies><novel strategy><outcome disparities><outcome inequality><outcome inequity><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><preservation><prevent><preventing><response><restore function><restore functionality><restore lost function><social role><trial regimen><trial treatment><type 2 DM><type II DM><type two diabetes><unequal effect><unequal impact><unequal outcome><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrew Stephen Bomback

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$592,933

FY 2026

Project Title

The Impact of Diabetes on Patients with Glomerular Disease: CureGN-Diabetes

Grant Number:

5R01DK126959-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/11/2021

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Primary glomerular diseases often occur in patients with prexisting diabetes mellitus, a common and systemic illness which increases the risk for infection, cardiovascular and progressive chronic kidney disease. The diagnosis, pathology, treatment, complications and outcomes of primary glom...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Ancillary Study><Area><Berger's Disease><Biological Markers><Biopsy><Body Tissues><Calcineurin antagonist><Calcineurin inhibitor><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Collection><Complex><Data><Data Collection><Diabetes Mellitus><Diabetic Glomerulosclerosis><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disorder><Enrollment><Epidemiology><Exclusion><Extramembranous Glomerulopathy><FSGS><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foot Process><Funding><Future><Glomerular disease><Health Care><Heart Vascular><Histologic><Histologically><Histopathology><Hospital Admission><Hospitalization><IGA Glomerulonephritis><IGA Nephropathy><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Modulation Therapy><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infection><Infrastructure><Intracapillary Glomerulosclerosis><Investigators><Kidney><Kidney Urinary System><Kimmelstiel-Wilson Disease><Kimmelstiel-Wilson Syndrome><Knowledge><Lesion><Lesion by Morphology><Letters><Literature><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal observational study><Mediating><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Minority><Morbidity><Morphology><Movement><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Nodular glomerulosclerosis><Outcome><Parents><Pathologic><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pedicel><Persons><Population><Precision care><Productivity><Protocol><Protocols documentation><QOL><Quality of life><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sclerosis><Severities><Site><Specificity><Standardization><Steroid Compound><Steroids><Time><Tissues><United States National Institutes of Health><Variant><Variation><Work><active followup><adulthood><bio-markers><biobank><biologic marker><biomarker><biorepository><body movement><cardiovascular disorder><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical research site><clinical site><co-morbid><co-morbidity><cohort><comorbidity><cost><data harmonization><diabetes><diabetic><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease diagnosis><disease heterogeneity><enroll><epidemiologic><epidemiological><focal glomerulonephritis><follow up><follow-up><followed up><followup><harmonized data><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><individual patient><individualized care><individualized patient care><infection risk><kidney biopsy><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><multi-ethnic><multiethnic><parent><pathway><patient oriented outcomes><personalized care><personalized patient care><precision medicine><precision-based medicine><predict clinical outcome><primary outcome><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><recruit><renal><renal biopsy><segmental glomerulonephritis><therapeutic immunomodulation><therapeutic immunoregulation><tool><treatment risk>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gaia Muallem Coppock

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$592,933

FY 2026

Project Title

The Impact of Diabetes on Patients with Glomerular Disease: CureGN-Diabetes

Grant Number:

5R01DK126959-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/11/2021

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Primary glomerular diseases often occur in patients with prexisting diabetes mellitus, a common and systemic illness which increases the risk for infection, cardiovascular and progressive chronic kidney disease. The diagnosis, pathology, treatment, complications and outcomes of primary glom...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Ancillary Study><Area><Berger's Disease><Biological Markers><Biopsy><Body Tissues><Calcineurin antagonist><Calcineurin inhibitor><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Collection><Complex><Data><Data Collection><Diabetes Mellitus><Diabetic Glomerulosclerosis><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disorder><Enrollment><Epidemiology><Exclusion><Extramembranous Glomerulopathy><FSGS><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foot Process><Funding><Future><Glomerular disease><Health Care><Heart Vascular><Histologic><Histologically><Histopathology><Hospital Admission><Hospitalization><IGA Glomerulonephritis><IGA Nephropathy><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Modulation Therapy><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infection><Infrastructure><Intracapillary Glomerulosclerosis><Investigators><Kidney><Kidney Urinary System><Kimmelstiel-Wilson Disease><Kimmelstiel-Wilson Syndrome><Knowledge><Lesion><Lesion by Morphology><Letters><Literature><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal observational study><Mediating><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Minority><Morbidity><Morphology><Movement><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Nodular glomerulosclerosis><Outcome><Parents><Pathologic><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pedicel><Persons><Population><Precision care><Productivity><Protocol><Protocols documentation><QOL><Quality of life><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sclerosis><Severities><Site><Specificity><Standardization><Steroid Compound><Steroids><Time><Tissues><United States National Institutes of Health><Variant><Variation><Work><active followup><adulthood><bio-markers><biobank><biologic marker><biomarker><biorepository><body movement><cardiovascular disorder><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical research site><clinical site><co-morbid><co-morbidity><cohort><comorbidity><cost><data harmonization><diabetes><diabetic><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease diagnosis><disease heterogeneity><enroll><epidemiologic><epidemiological><focal glomerulonephritis><follow up><follow-up><followed up><followup><harmonized data><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><individual patient><individualized care><individualized patient care><infection risk><kidney biopsy><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><multi-ethnic><multiethnic><parent><pathway><patient oriented outcomes><personalized care><personalized patient care><precision medicine><precision-based medicine><predict clinical outcome><primary outcome><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><recruit><renal><renal biopsy><segmental glomerulonephritis><therapeutic immunomodulation><therapeutic immunoregulation><tool><treatment risk>

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Amy Mottl

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$592,933

FY 2026

Project Title

The Impact of Diabetes on Patients with Glomerular Disease: CureGN-Diabetes

Grant Number:

5R01DK126959-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/11/2021

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Primary glomerular diseases often occur in patients with prexisting diabetes mellitus, a common and systemic illness which increases the risk for infection, cardiovascular and progressive chronic kidney disease. The diagnosis, pathology, treatment, complications and outcomes of primary glom...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Ancillary Study><Area><Berger's Disease><Biological Markers><Biopsy><Body Tissues><Calcineurin antagonist><Calcineurin inhibitor><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Collection><Complex><Data><Data Collection><Diabetes Mellitus><Diabetic Glomerulosclerosis><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disorder><Enrollment><Epidemiology><Exclusion><Extramembranous Glomerulopathy><FSGS><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foot Process><Funding><Future><Glomerular disease><Health Care><Heart Vascular><Histologic><Histologically><Histopathology><Hospital Admission><Hospitalization><IGA Glomerulonephritis><IGA Nephropathy><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Modulation Therapy><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infection><Infrastructure><Intracapillary Glomerulosclerosis><Investigators><Kidney><Kidney Urinary System><Kimmelstiel-Wilson Disease><Kimmelstiel-Wilson Syndrome><Knowledge><Lesion><Lesion by Morphology><Letters><Literature><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal observational study><Mediating><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Minority><Morbidity><Morphology><Movement><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Nodular glomerulosclerosis><Outcome><Parents><Pathologic><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pedicel><Persons><Population><Precision care><Productivity><Protocol><Protocols documentation><QOL><Quality of life><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sclerosis><Severities><Site><Specificity><Standardization><Steroid Compound><Steroids><Time><Tissues><United States National Institutes of Health><Variant><Variation><Work><active followup><adulthood><bio-markers><biobank><biologic marker><biomarker><biorepository><body movement><cardiovascular disorder><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical research site><clinical site><co-morbid><co-morbidity><cohort><comorbidity><cost><data harmonization><diabetes><diabetic><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease diagnosis><disease heterogeneity><enroll><epidemiologic><epidemiological><focal glomerulonephritis><follow up><follow-up><followed up><followup><harmonized data><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><individual patient><individualized care><individualized patient care><infection risk><kidney biopsy><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><multi-ethnic><multiethnic><parent><pathway><patient oriented outcomes><personalized care><personalized patient care><precision medicine><precision-based medicine><predict clinical outcome><primary outcome><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><recruit><renal><renal biopsy><segmental glomerulonephritis><therapeutic immunomodulation><therapeutic immunoregulation><tool><treatment risk>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Cynthia C. Nast

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$592,933

FY 2026

Project Title

The Impact of Diabetes on Patients with Glomerular Disease: CureGN-Diabetes

Grant Number:

5R01DK126959-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/11/2021

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Primary glomerular diseases often occur in patients with prexisting diabetes mellitus, a common and systemic illness which increases the risk for infection, cardiovascular and progressive chronic kidney disease. The diagnosis, pathology, treatment, complications and outcomes of primary glom...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Ancillary Study><Area><Berger's Disease><Biological Markers><Biopsy><Body Tissues><Calcineurin antagonist><Calcineurin inhibitor><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Collection><Complex><Data><Data Collection><Diabetes Mellitus><Diabetic Glomerulosclerosis><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disorder><Enrollment><Epidemiology><Exclusion><Extramembranous Glomerulopathy><FSGS><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foot Process><Funding><Future><Glomerular disease><Health Care><Heart Vascular><Histologic><Histologically><Histopathology><Hospital Admission><Hospitalization><IGA Glomerulonephritis><IGA Nephropathy><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Modulation Therapy><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infection><Infrastructure><Intracapillary Glomerulosclerosis><Investigators><Kidney><Kidney Urinary System><Kimmelstiel-Wilson Disease><Kimmelstiel-Wilson Syndrome><Knowledge><Lesion><Lesion by Morphology><Letters><Literature><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal observational study><Mediating><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Minority><Morbidity><Morphology><Movement><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Nodular glomerulosclerosis><Outcome><Parents><Pathologic><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pedicel><Persons><Population><Precision care><Productivity><Protocol><Protocols documentation><QOL><Quality of life><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sclerosis><Severities><Site><Specificity><Standardization><Steroid Compound><Steroids><Time><Tissues><United States National Institutes of Health><Variant><Variation><Work><active followup><adulthood><bio-markers><biobank><biologic marker><biomarker><biorepository><body movement><cardiovascular disorder><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical research site><clinical site><co-morbid><co-morbidity><cohort><comorbidity><cost><data harmonization><diabetes><diabetic><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease diagnosis><disease heterogeneity><enroll><epidemiologic><epidemiological><focal glomerulonephritis><follow up><follow-up><followed up><followup><harmonized data><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><individual patient><individualized care><individualized patient care><infection risk><kidney biopsy><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><multi-ethnic><multiethnic><parent><pathway><patient oriented outcomes><personalized care><personalized patient care><precision medicine><precision-based medicine><predict clinical outcome><primary outcome><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><recruit><renal><renal biopsy><segmental glomerulonephritis><therapeutic immunomodulation><therapeutic immunoregulation><tool><treatment risk>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JIALING LIU

NORTHERN CALIFORNIA INSTITUTE/RES/EDU, SAN FRANCISCO, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$591,470

FY 2026

Project Title

Type 2 diabetes induced chronic inflammation on stroke outcome

Grant Number:

5R01NS137082-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Type 2 diabetes (T2DM) not only increases the risk of stroke, but also worsens the stroke outcome. Poor blood perfusion, hypercoagulability and chronic inflammation are known to be contributing factors. Complement activation products, especially C3 opsonins and the C3a/C5a anaphylaxis, have been imp...

Research Terms

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Todd Michael Brusko

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$590,577

FY 2026

Project Title

The CD226 costimulatory axis in type 1 diabetes

Grant Number:

5R01DK106191-09

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2016

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT. Type 1 diabetes (T1D) results from complex interactions between over 150 independent loci imparting disease susceptibility and environmental factors that break immune tolerance, leading to the immune- mediated destruction of insulin-producing pancreatic -cells. Among these exists a small ...

Research Terms

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

David W Piston

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$578,846

FY 2026

Project Title

Brown adipose tissue derived nidogen-2 as a diabetes therapeutic

Grant Number:

1R01DK143569-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2026

End Date:

1/31/2031

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Diabetes is characterized by insufficient insulin, and both type 1 (T1D) and advanced type 2 diabetes (T2D) are treated with insulin. One drawback of insulin-only therapy is the risk of hypoglycemia, and alternatives could improve the quality of life for people with diabetes. Destruction of β-cells ...

Research Terms

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MIHAELA STEFAN-LIFSHITZ

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$568,896

FY 2026

Project Title

Analyzing Genes for Autoimmune Thyroiditis and Diabetes: Translation to Therapy

Grant Number:

5R01DK067555-17

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2005

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Autoimmune thyroid diseases (AITD) frequently develop together with type 1 diabetes (T1D), a phenotype considered a variant of the Autoimmune Polyglandular Syndrome type 3 (APS3v). The overall goal of our work is to map and sequence the joint susceptibility genes for AITD and T1D, to...

Research Terms

<3' Untranslated Regions><3'UTR><Acceleration><All-D-Retro Peptide><Alleles><Allelomorphs><Amino Acids><Antigens><Assay><Autoantigens><Autoimmune Diabetes><Autoimmune Polyendocrinopathies><Autoimmune Status><Autoimmune thyroiditis><Autoimmunity><Autologous Antigens><Automobile Driving><Basedow's Disease><Beta Cell><Binding><Bioassay><Biological><Biological Assay><Blood><Blood Reticuloendothelial System><Brittle Diabetes Mellitus><CD152><CD152 Antigen><CD152 Gene><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 gene><CTLA4-TM><Causality><Cell Body><Cell Isolation><Cell Line><Cell Segregation><Cell Separation><Cell Separation Technology><Cell model><CellLine><Cells><Cellular model><Chronic Lymphocytic Thyroiditis><Chronic thyroiditis><Complex><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><DNA mutation><Disease><Disorder><ELISA><Environmental Factor><Environmental Risk Factor><Enzyme-Linked Immunosorbent Assay><Etiology><Exophthalmic Goiter><FOXP3><FOXP3 gene><Forkhead Box P3><Gamma-delta T cells><Gene variant><Genes><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Graves' Disease><HLA-DR3><HLA-DR3 Antigen><Hashimoto Disease><Hashimoto's Disease><Hashimoto's Struma><Hashimoto's Thyroiditis><Hashimoto's syndrome><Hashimotos Disease><IDDM><Immune mediated therapy><Immunologically Directed Therapy><Immunotherapy><Individual><Inflammation><Inflammatory><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><JM2><Joints><Juvenile-Onset Diabetes Mellitus><K562 Cells><Ketosis-Prone Diabetes Mellitus><Knowledge><Lead><Link><Lymphocytic Thyroiditis><Lymphomatous Thyroiditis><Maps><Mediating><Mice><Mice Mammals><MicroRNAs><Molecular Configuration><Molecular Conformation><Molecular Dynamics Simulation><Molecular Interaction><Molecular Stereochemistry><Mononuclear><Murine><Mus><Mutation><NGS Method><NGS system><PBMC><Pancreatic Secretion><Pancreatic beta Cell><Pancreatic β-Cell><Pathogenicity><Pathway interactions><Patients><Pb element><Peptides><Peripheral Blood Mononuclear Cell><Phenotype><Predisposition gene><Proteins><Regulation><Regulatory T-Lymphocyte><Retro-Enantio Peptide><Retro-Inverso Analog><Retro-Inverso Derivative><Retro-Inverso Isomer><Retro-Inverso Peptide><Risk><Role><SCURFIN><Self-Antigens><Strains Cell Lines><Stress><Structure of beta Cell of islet><Sudden-Onset Diabetes Mellitus><Susceptibility Gene><T-Cell Activation><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><T1 DM><T1 diabetes><T1D><T1DM><Testing><Therapeutic><Thyroid><Thyroid Gland><Thyroid Head and Neck><Time><Translating><Translations><Treg><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Variant><Variation><Work><activate T cells><allelic variant><aminoacid><antigen binding><antigen bound><autoimmune beta cell destruction><autoimmune islet destruction><autoimmune polyendocrine syndrome><autoimmune polyglandular syndrome><autoimmune thyroid disease><autoimmune thyroid disorder><autoreactive T cell><beta cell autoimmunity><biologic><butyrophilin><causal allele><causal gene><causal mutation><causal variant><causation><causative mutation><causative variant><cell sorting><conformation><conformational><conformational state><conformationally><conformations><cultured cell line><cytotoxic T-lymphocyte antigen 4><design><designing><disease causation><driving><environmental risk><enzyme linked immunoassay><exosome><experience><extracellular vesicles><gene interaction><genetic variant><genome mutation><genomic variant><heavy metal Pb><heavy metal lead><humanized mice><humanized mouse><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunogen><in silico><in vitro testing><in vivo><insulin dependent diabetes><insulin dependent type 1><islet><islet autoimmunity><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><low-frequency mutation><miRNA><molecular dynamics><mouse model><multidisciplinary><murine model><mutant><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next gen sequencing><next generation sequencing><next generation therapeutics><nextgen sequencing><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><overexpress><overexpression><pancreas beta cell><pancreas β cell><pancreatic b-cell><pancreatic juice><pathway><pre-clinical development><preclinical development><predisposing gene><rare allele><rare mutation><rare variant><regulatory T-cells><screening><screenings><self-reactive T cell><social role><susceptibility allele><susceptibility locus><susceptibility variant><thymus derived lymphocyte><translation><translational study><type I diabetes><type one diabetes><uptake><β-cell><β-cells><βCell><γδ T cells><γδT cells>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

YARON TOMER

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$568,896

FY 2026

Project Title

Analyzing Genes for Autoimmune Thyroiditis and Diabetes: Translation to Therapy

Grant Number:

5R01DK067555-17

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2005

End Date:

11/30/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Autoimmune thyroid diseases (AITD) frequently develop together with type 1 diabetes (T1D), a phenotype considered a variant of the Autoimmune Polyglandular Syndrome type 3 (APS3v). The overall goal of our work is to map and sequence the joint susceptibility genes for AITD and T1D, to...

Research Terms

<3' Untranslated Regions><3'UTR><Acceleration><All-D-Retro Peptide><Alleles><Allelomorphs><Amino Acids><Antigens><Assay><Autoantigens><Autoimmune Diabetes><Autoimmune Polyendocrinopathies><Autoimmune Status><Autoimmune thyroiditis><Autoimmunity><Autologous Antigens><Automobile Driving><Basedow's Disease><Beta Cell><Binding><Bioassay><Biological><Biological Assay><Blood><Blood Reticuloendothelial System><Brittle Diabetes Mellitus><CD152><CD152 Antigen><CD152 Gene><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 gene><CTLA4-TM><Causality><Cell Body><Cell Isolation><Cell Line><Cell Segregation><Cell Separation><Cell Separation Technology><Cell model><CellLine><Cells><Cellular model><Chronic Lymphocytic Thyroiditis><Chronic thyroiditis><Complex><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><DNA mutation><Disease><Disorder><ELISA><Environmental Factor><Environmental Risk Factor><Enzyme-Linked Immunosorbent Assay><Etiology><Exophthalmic Goiter><FOXP3><FOXP3 gene><Forkhead Box P3><Gamma-delta T cells><Gene variant><Genes><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Graves' Disease><HLA-DR3><HLA-DR3 Antigen><Hashimoto Disease><Hashimoto's Disease><Hashimoto's Struma><Hashimoto's Thyroiditis><Hashimoto's syndrome><Hashimotos Disease><IDDM><Immune mediated therapy><Immunologically Directed Therapy><Immunotherapy><Individual><Inflammation><Inflammatory><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><JM2><Joints><Juvenile-Onset Diabetes Mellitus><K562 Cells><Ketosis-Prone Diabetes Mellitus><Knowledge><Lead><Link><Lymphocytic Thyroiditis><Lymphomatous Thyroiditis><Maps><Mediating><Mice><Mice Mammals><MicroRNAs><Molecular Configuration><Molecular Conformation><Molecular Dynamics Simulation><Molecular Interaction><Molecular Stereochemistry><Mononuclear><Murine><Mus><Mutation><NGS Method><NGS system><PBMC><Pancreatic Secretion><Pancreatic beta Cell><Pancreatic β-Cell><Pathogenicity><Pathway interactions><Patients><Pb element><Peptides><Peripheral Blood Mononuclear Cell><Phenotype><Predisposition gene><Proteins><Regulation><Regulatory T-Lymphocyte><Retro-Enantio Peptide><Retro-Inverso Analog><Retro-Inverso Derivative><Retro-Inverso Isomer><Retro-Inverso Peptide><Risk><Role><SCURFIN><Self-Antigens><Strains Cell Lines><Stress><Structure of beta Cell of islet><Sudden-Onset Diabetes Mellitus><Susceptibility Gene><T-Cell Activation><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><T1 DM><T1 diabetes><T1D><T1DM><Testing><Therapeutic><Thyroid><Thyroid Gland><Thyroid Head and Neck><Time><Translating><Translations><Treg><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Variant><Variation><Work><activate T cells><allelic variant><aminoacid><antigen binding><antigen bound><autoimmune beta cell destruction><autoimmune islet destruction><autoimmune polyendocrine syndrome><autoimmune polyglandular syndrome><autoimmune thyroid disease><autoimmune thyroid disorder><autoreactive T cell><beta cell autoimmunity><biologic><butyrophilin><causal allele><causal gene><causal mutation><causal variant><causation><causative mutation><causative variant><cell sorting><conformation><conformational><conformational state><conformationally><conformations><cultured cell line><cytotoxic T-lymphocyte antigen 4><design><designing><disease causation><driving><environmental risk><enzyme linked immunoassay><exosome><experience><extracellular vesicles><gene interaction><genetic variant><genome mutation><genomic variant><heavy metal Pb><heavy metal lead><humanized mice><humanized mouse><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunogen><in silico><in vitro testing><in vivo><insulin dependent diabetes><insulin dependent type 1><islet><islet autoimmunity><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><low-frequency mutation><miRNA><molecular dynamics><mouse model><multidisciplinary><murine model><mutant><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next gen sequencing><next generation sequencing><next generation therapeutics><nextgen sequencing><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><overexpress><overexpression><pancreas beta cell><pancreas β cell><pancreatic b-cell><pancreatic juice><pathway><pre-clinical development><preclinical development><predisposing gene><rare allele><rare mutation><rare variant><regulatory T-cells><screening><screenings><self-reactive T cell><social role><susceptibility allele><susceptibility locus><susceptibility variant><thymus derived lymphocyte><translation><translational study><type I diabetes><type one diabetes><uptake><β-cell><β-cells><βCell><γδ T cells><γδT cells>

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Sarah A. Tersey

UNIVERSITY OF CHICAGO, CHICAGO, IL

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$550,564

FY 2026

Project Title

The Role of Polyamines and Hypusine in Beta-Cell Dysfunction

Grant Number:

5R01DK135832-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT ABSTRACT There is a massive prevalence of diabetes in the U.S. with 34.2 million having diabetes, and 88 million adults with prediabetes. Type 1 diabetes results from the autoimmune destruction of the islet β cell mediated in part by β-cell dysfunction prior to autoimmune attack. Polyamine a...

Research Terms

<1,4-Butanediamine><1,4-Diaminobutane><21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Amines><Amino Acids><Anabolism><Apoptotic><Applications Grants><Arginine><Autoimmune><Autoimmune Status><Autoimmunity><B-Cells><B-Lymphocytes><B-cell><B9 endocrine pancreas><Beta Cell><Brittle Diabetes Mellitus><Cell Body><Cell Communication and Signaling><Cell Death><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cessation of life><Chronic stress><Cytokine Activation><DFMO><DL-alpha-Difluoromethylornithine><DL-α-Difluoromethylornithine><DNA Replication><DNA Synthesis><DNA biosynthesis><Data><Death><Defect><Development><Diabetes Mellitus><Diet><Disease><Disorder><Dysfunction><ER stress><Endocrine Pancreas><Endoplasmic Reticulum><Enzyme Gene><Enzymes><Ergastoplasm><Functional disorder><Gene Transcription><Genetic><Genetic Transcription><Grant Proposals><Health><Human><Humulin R><IDDM><IF-5A><Immune Cell Activation><Immunologic Subtyping><Immunophenotyping><Inbred NOD Mice><Incidence><Inflammation><Inflammatory><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin deficiency><Insulin-Dependent Diabetes Mellitus><Intervention><Intracellular Communication and Signaling><Islands of Langerhans><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><L-Arginine><L-Ornithine carboxy-lyase><Lymph Node Reticuloendothelial System><Lymph node proper><Lymphatic nodes><Maturity-Onset Diabetes Mellitus><Mediating><Messenger RNA><Mice><Mice Mammals><Modern Man><Molecular><Monitor><Murine><Mus><NIDDM><NOD Mouse><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Obese Diabetic Mice><Non-Polyadenylated RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonobese Diabetic Mouse><Novolin R><Ornithine Carboxy-lyase><Ornithine Decarboxylase><Pancreatic Islets><Pars endocrina pancreatis><Pathogenesis><Pathway interactions><Phase><Physiopathology><Polyamine Compound><Polyamines><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Production><Proinsulin><Proteins><Putrescine><RNA><RNA Expression><RNA Gene Products><Reagent><Regular Insulin><Resolution><Ribonucleic Acid><Ribosomes><Role><Sampling><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Spermidine><Spermine><Spleen><Spleen Reticuloendothelial System><Stable Diabetes Mellitus><Stress><Subcellular Process><Sudden-Onset Diabetes Mellitus><T cell response><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Techniques><Technology><Testing><Tetramethylenediamine><Transcription><Translations><Treatment Efficacy><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><aberrant folded protein><aberrant folded proteins><abnormal folded protein><abnormal folded proteins><acute stress><adult onset diabetes><adulthood><amine><aminoacid><autoimmune attack><autoimmune beta cell destruction><autoimmune destruction><autoimmune islet destruction><autoimmune pathogenesis><beta cell autoimmunity><biological adaptation to stress><biological signal transduction><biosynthesis><cytokine><deoxyhypusine synthase><determine efficacy><developmental><diabetes><diabetes pathogenesis><diets><difluoromethylornithine><eIF-4D><eIF-5A><eIF5A protein><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><endoplasmic reticulum stress><eukaryotic initiation factor-4D><evaluate efficacy><examine efficacy><human model><hypusine><immune activation><immunogenicity><inhibitor><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulin resistant><insulin tolerance><intervention efficacy><islet><islet autoimmunity><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lymph gland><lymph nodes><lymphnodes><mRNA><mRNA Translation><maturity onset diabetes><misfolded protein><misfolded proteins><model of human><mouse model><murine model><necrocytosis><neo-antigen><neo-epitopes><neoantigens><neoepitopes><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel><pathophysiology><pathway><pre-diabetes><pre-diabetic><prediabetic><preservation><proteotoxic protein><proteotoxin><reactioncrisis><resolutions><response><social role><stress response><stressreaction><therapeutic efficacy><therapy efficacy><tool><translation><translation factor><type 1 diabetes onset><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><β-cell><β-cells><βCell>

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Mark O. Huising

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$482,979

FY 2026

Project Title

Paracrine feedback by pancreatic delta cells to control glucagon and insulin release and manage diabetes

Grant Number:

5R01DK110276-09

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2017

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Half of US adults have diabetes or pre-diabetes, illustrating a critical need for novel treatments. There is a fundamental gap in the understanding of how paracrine feedback in the islet controls insulin and glucagon. The long-term goal is to elucidate the (patho)physiological crosstalk within pancr...

Research Terms

<21+ years old><3'5'-cyclic ester of AMP><Address><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Adult><Adult Human><Agonist><Alpha Cell><American><Antidiabetic Hormone><Ants><Attenuated><B9 endocrine pancreas><Behavior><Beta Cell><Biosensor><CDC42><CDC42 gene><CDC42Hs><Calcium><Cell Body><Cell surface><Cells><Cellular Matrix><Cilia><Coloring Agents><Communicating Junction><Congenital Hyperinsulinism><Congenital hyperinsulinemia><Cyclic AMP><Cyclic Somatostatin><Cytoskeletal System><Cytoskeleton><D Cells><D-Glucose><Delta Cell><Dextrose><Diabetes Mellitus><Disease><Disorder><Dyes><Endocrine Gland Secretion><Endocrine Pancreas><Epidemic><Equilibrium><Exocytosis><Exocytosis Inhibition><F-Actin><FRET><Feedback><Filamentous Actin><Fluorescence Resonance Energy Transfer><Förster Resonance Energy Transfer><G25K><GTP Phosphohydrolases><GTPases><Gap Junctions><Gene Transcription><Genetic Transcription><Glucagon><Glucagon Cell><Glucagon Secreting Cell><Glucose><Glukagon><Goals><Growth Hormone Inhibiting Factors><Growth Hormone-Inhibiting Hormone><Guanosine Triphosphate Phosphohydrolases><Guanosinetriphosphatases><HG-Factor><Health><Hormones><Humulin R><Hyperglycemia><Hyperglycemic-Glycogenolytic Factor><Hyperinsulinemia Hypoglycemia of Infancy><Hypoglycemia><Hypoglycemia of Infancy><Individual><Injections><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin deficiency><Insulin homeostasis><Islands of Langerhans><Islet Cell><Islets of Langerhans><Learning><Literature><Liver><Low-resistance Junction><Measures><Mediating><Mission><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Nesidioblasts><Nexus Junction><Novolin R><Nutrient><PHHI Hypoglycemia><Pancreatic Islets><Pancreatic Somatostatin Cell><Pancreatic Somatostatin Secreting Cell><Pancreatic beta Cell><Pancreatic delta Cell><Pancreatic β-Cell><Pancreatic δ Cell><Pars endocrina pancreatis><Pathway interactions><Patients><Persistent Hyperinsulinemia Hypoglycemia of Infancy><Physiologic><Physiological><Physiology><Position><Positioning Attribute><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Public Health><Publishing><QOL><Quality of life><RNA Expression><Regular Insulin><Research><Role><SRIH><SRIH Receptors><SRIH-14><SSTR2><SSTR2 gene><SSTR3><SSTR3 gene><Somatostatin><Somatostatin Cell of the Pancreas><Somatostatin Cells><Somatostatin Receptor><Somatostatin Secreting Cell><Somatostatin Secreting Cell of the Pancreas><Somatostatin-14><Somatotropin Release Inhibiting Factors><Somatotropin Release Inhibiting Hormone Receptors><Somatotropin Release-Inhibiting Hormone><Source><Structure of beta Cell of islet><Testing><Therapeutic><Therapeutic Hormone><Time><Tolbutamide><Transcription><Translating><adenosine 3'5' monophosphate><adulthood><alpha-cell><attenuate><attenuates><balance><balance function><biological sensor><blood glucose regulation><cAMP><cell behavior><cellular behavior><diabetes><diabetes management><diabetes mellitus management><diabetic management><experiment><experimental research><experimental study><experiments><glucose control><glucose homeostasis><glucose regulation><growth hormone release inhibiting factor><guanosinetriphosphatase><hepatic body system><hepatic organ system><hyperglycemic><hypoglycemic><hypoglycemic episodes><improved><innovate><innovation><innovative><insulin balance><insulin control><insulin secretion><intracellular skeleton><islet><new approaches><new drug target><new druggable target><new pharmacotherapy target><new technology><new therapeutic target><new therapy target><novel><novel approaches><novel drug target><novel druggable target><novel pharmacotherapy target><novel strategies><novel strategy><novel technologies><novel therapeutic target><novel therapy target><pancreas beta cell><pancreas delta cell><pancreas β cell><pancreatic b-cell><paracrine><pathway><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><response><restraint><social role><standard care><standard treatment><type 1 and type 2 diabetes><type I and type II diabetes><α-cell><β-cell><β-cells><βCell>

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Virginia Smith Shapiro

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$454,682

FY 2026

Project Title

Inhibition of autoimmune diabetes by ST8Sia6

Grant Number:

5R01DK136208-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Abstract Autoimmune diseases can occur in nearly any part of the body, and pose a significant problem in human health, including both systemic autoimmunity and tissue-specific autoimmunity. 1.25 million Americans have type 1 diabetes (T1D), where the immune system destroys insulin-producing beta ce...

Research Terms

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Matthew Ng Poy

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$409,375

FY 2026

Project Title

PITPNA in pancreatic beta-cell dysfunction and diabetes pathogenesis

Grant Number:

5R01DK135688-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Critical to successful innovation in treating diabetes is the development of strategies for promoting insulin release and preventing pancreatic beta-cell destruction. Chronic demand for insulin production during insulin resistance and diabetes exacerbates cell dysfunction and this i...

Research Terms

<1-Phosphatidylinositol 4-Kinase><Adult-Onset Diabetes Mellitus><B9 endocrine pancreas><Beta Cell><Cell Body><Cell Death><Cell Fractionation><Cell Function><Cell Physiology><Cell Process><Cell membrane><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chronic><Cytoplasmic Granules><Cytoplasmic Membrane><Data><Defect><Development><Diabetes Mellitus><Docking><Dysfunction><EC 2.7.1.67><ER stress><Endocrine Pancreas><Endoplasmic Reticulum><Ergastoplasm><Exocytosis><Failure><Functional disorder><Heat shock proteins><Human><Humulin R><Hyperglycemia><Impairment><Individual><Inositide Phospholipids><Inositol Phosphoglycerides><Inositol Phospholipids><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intracellular Membranes><Islands of Langerhans><Islets of Langerhans><Ketosis-Resistant Diabetes Mellitus><Link><LoxP-flanked allele><Maturity-Onset Diabetes Mellitus><Membrane><Methods><Mice><Mice Mammals><Mitochondria><Modern Man><Morphology><Murine><Mus><NIDDM><NPIK><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Oxidative Stress><PI 4-Kinase><PI Transfer Protein><PI4K92><PI4KBeta><Pancreas><Pancreatic><Pancreatic Islets><Pancreatic beta Cell><Pancreatic β-Cell><Pars endocrina pancreatis><Pathway interactions><Phosphatides><Phosphatidyl Inositol><Phosphatidylinositiol Kinase><Phosphatidylinositol 4-Kinase><Phosphatidylinositol 4-Kinase Beta><Phosphatidylinositol 4-Kinase, Catalytic, Beta><Phosphatidylinositol 4-Kinase, Type III, Beta><Phosphatidylinositol Exchange Protein><Phosphatidylinositol Kinase Type II><Phosphatidylinositol Transfer Protein><Phosphatidylinositols><Phosphoinositide Kinase><Phosphoinositide-4-Kinase Catalytic Beta Polypeptide><Phosphoinositides><Phospholipids><Phosphorylation><Physiopathology><Plasma Membrane><Production><Proinsulin><Protein Phosphorylation><PtdINS4P><PtdIns><PtdIns 4-Kinase><Regular Insulin><Role><Secretory Granules><Secretory Vesicles><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure of beta Cell of islet><Subcellular Process><T2 DM><T2D><T2DM><Testing><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Wortmannin-Sensitive Phosphatidylinositol 4-Kinase><adult onset diabetes><attenuated insulin secretion><blunted insulin secretion><decreased insulin release><decreased insulin secretion><defective insulin secretion><developmental><diabetes><diabetes pathogenesis><diminished insulin release><diminished insulin secretion><endoplasmic reticulum stress><floxed><floxed allele><granule><human subject><hyperglycemic><impaired insulin release><impaired insulin secretion><improved><inadequate insulin release><inadequate insulin secretion><innovate><innovation><innovative><insulin granule><insulin resistant><insulin secretion><insulin tolerance><islet><ketosis resistant diabetes><knock-down><knockdown><lowered insulin secretion><maturity onset diabetes><membrane structure><mitochondrial><mitochondrial dysfunction><mitochondrial membrane><necrocytosis><new approaches><novel approaches><novel strategies><novel strategy><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><pathway><pharmacologic><phosphatidylinositol 4-monophosphate><phosphatidylinositol 4-phosphate><plasmalemma><prevent><preventing><reduced insulin release><restoration><social role><stress protein><subcellular fractionation><suppressed insulin release><suppressed insulin secretion><trans-Golgi Network><type 2 DM><type II DM><type two diabetes><β-cell><β-cells><βCell>

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Jun Yoshioka

CITY COLLEGE OF NEW YORK, NEW YORK, NY

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$392,500

FY 2026

Project Title

Hyperglycemia-induced regulatory mechanism of ER stress by arresting domain-containing protein 4 in diabetic cardiomyopathy

Grant Number:

5R01HL168191-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/15/2024

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT The endoplasmic reticulum (ER) is an organelle that houses factors that assist proteins in their folding and supports the formation of stabilizing covalent modifications. Perturbation of ER functions results in evolutionarily conserved cell stress, the unfolded protein response (UPR). Recen...

Research Terms

<21+ years old><Adaptor Protein><Adaptor Protein Gene><Adaptor Signaling Protein><Adaptor Signaling Protein Gene><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Anabolism><Animal Model><Animal Models and Related Studies><Animals><Apoptosis><Apoptosis Pathway><Arrestins><Basal Transcription Factor><Basal transcription factor genes><Binding><Body Tissues><Brittle Diabetes Mellitus><Carbohydrates><Cardiac><Cardiac Diseases><Cardiac Disorders><Cardiac Muscle Cells><Cardiac Myocytes><Cardiocyte><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cell Body><Cell Communication and Signaling><Cell Death><Cell Signaling><Cell membrane><Cells><Cellular Stress><Cellular Stress Response><Cessation of life><Clinical><Clinical Research><Clinical Study><Complication><Cytoplasmic Membrane><D-Glucose><Data><Death><Defense Mechanisms><Development><Dextrose><Diabetes Mellitus><Diabetic mouse><ER stress><Endocytosis><Endoplasmic Reticulum><Energy Expenditure><Energy Metabolism><Ergastoplasm><Erythrocyte/Hepatoma Glucose Transporter><Event><Exercise Tolerance><Exhibits><Family><Fasting Hypoglycemia><Future><GLUT><GLUT1><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Transcription><Glucose><Glucose Transporter 1><Heart><Heart Diseases><Heart Muscle Cells><Heart Vascular><Heart myocyte><Hexosamines><High Fat Diet><Humulin R><Hyperglycemia><IDDM><Individual><Insulin><Insulin deficiency><Insulin-Dependent Diabetes Mellitus><Intermediary Metabolism><Intracellular Communication and Signaling><Juvenile-Onset Diabetes Mellitus><KO mice><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Knowledge><Left><Link><Maturity-Onset Diabetes Mellitus><Mediating><Metabolic Processes><Metabolic stress><Metabolism><Mice><Mice Mammals><Modeling><Modification><Molecular><Molecular Interaction><Murine><Mus><Muscle><Muscle Tissue><Myocardial><Myocardial Diseases><Myocardial Disorder><Myocardial depression><Myocardial dysfunction><Myocardiopathies><NIDDM><Nature><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Null Mouse><Nutrient><Organelles><Pathogenesis><Pathway interactions><Peripheral><Plasma Membrane><Postabsorptive Hypoglycemia><Prognosis><Programmed Cell Death><Protein Glycosylation><Proteins><Proteomics><RNA Expression><Receptor Protein><Regular Insulin><Response Elements><Retinal S-Antigen><Role><SLC2A1><SLC2A1 gene><Scaffolding Protein><Secondary to><Signal Transduction><Signal Transduction Systems><Signaling><Skeletal Muscle><Slow-Onset Diabetes Mellitus><Solute Carrier Family 2, Facilitated Glucose Transporter, Member 1><Stable Diabetes Mellitus><Starvation><Stress><Sudden-Onset Diabetes Mellitus><Syndrome><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Testing><Tissues><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type 2 diabetic><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Type II diabetic><Ubiquitilation><Ubiquitination><Ubiquitinoylation><Ventricular><Voluntary Muscle><adapter protein><adult onset diabetes><adulthood><biological signal transduction><biosynthesis><cardiac damage><cardiac dysfunction><cardiac function><cardiomyocyte><cardioprotectant><cardioprotection><cardioprotective><cell stress><circulatory system><db/db mouse><deprivation><developmental><diabetes><diabetes mouse model><diabetic><diabetic cardiomyopathy><diabetic cardiopathy><diabetic cardiopathy disease><diabetic cardiopathy disorder><diabetic cardiovascular disease><diabetic cardiovascular disorder><endoplasmic reticulum stress><exercise capacity><exercise intolerance><function of the heart><glucose uptake><glycemic control><heart damage><heart disorder><heart dysfunction><heart function><hyperglycemic><improved><in vivo><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><knowledge of results><maturity onset diabetes><member><metabolic phenotype><metabotype><model of animal><mortality><mouse model><murine model><muscular><myocardium disease><myocardium disorder><necrocytosis><overexpress><overexpression><pathway><plasmalemma><promoter><promotor><protein folding><proteotoxic><proteotoxicity><psychological defense mechanism><receptor><response><social role><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><trafficking><transcription factor><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><ubiquination><ubiquitin conjugation>

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Neha Pravin Gothe

NORTHEASTERN UNIVERSITY, BOSTON, MA

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$326,208

FY 2026

Project Title

Mindful Eating and Mindful Movement for Persons with Type 2 Diabetes Mellitus: A pilot RCT

Grant Number:

1R01DK145953-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/20/2026

End Date:

12/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary Type 2 diabetes mellitus (T2DM) is a chronic condition characterized by impaired blood glucose control ultimately leading to cardiovascular, renal, and cognitive dysfunction. T2DM prevalence continues to rise in the U.S., with massive health and financial consequences. Current diet a...

Research Terms

<18 year old><18 years of age><2 arm RCT><2 arm randomized control trial><2 arm randomized controlled trial><21+ years old><Accelerometer><Active Follow-up><Address><Adherence><Adopted><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aerobic Activity><Aerobic Exercise><Aerobic Training><Aerobic fitness><Aeroseb-HC><Affect><American><Area><Attitude><Automobile Driving><Awareness><Behavior><Behavioral><Binge Eating><Biological Markers><Blood Glucose><Blood Sugar><Body Composition><Body Weight decreased><Caloric Restriction><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cetacort><Chronic><Chronic Disease><Chronic Illness><Chronic stress><Clinical><Clinical Management><Clinical Trials><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complications of Diabetes Mellitus><Consumption><Control Groups><Cort-Dome><Cortef><Cortenema><Cortisol><Cortispray><Cortril><Counseling><Creativeness><Cues><Data><Dermacort><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diagnosis><Diet><Diet Habits><Dietary Assessment><Dietary Habits><Dietary Intervention><Dietary quality><Disability prevention><Disease><Disease Management><Disease Outcome><Disorder><Disorder Management><Disturbance in cognition><Eating Behavior><Effectiveness><Eldecort><Emotions><Enrollment><Exercise><Feedback><Food Preferences><Fostering><Foundations><Future><Guidelines><Health><Health behavior><Health behavior change><Healthy Eating><Heart Vascular><Hour><Hunger><Hydrocortisone><Hydrocortone><Hytone><Impaired cognition><Impairment><Individual><Inflammation><Informal Social Control><Intervention><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Life Style><Lifestyle><Lipids><Maintenance><Maturity-Onset Diabetes Mellitus><Measures><Mental Health><Mental Hygiene><Metabolic><Mindful Eating><Mission><Motivation><Movement><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutracort><Nutrient-dense food><Nutrition><Nutrition Interventions><Nutritional Interventions><Nutritious-dense food><Outcome><Participant><Patients><Personal awareness><Persons><Physical activity><Physiologic><Physiological><Pilot Projects><Play><Population><Position><Positioning Attribute><Prevalence><Preventing disabilities><Proctocort><Productivity><Psychological Health><Public Health><Randomized><Randomized, Controlled Trials><Recommendation><Research><Research Personnel><Researchers><Review Literature><Role><Satiation><Self Perception><Self Regulation><Self image><Self view><Single-Blind Study><Single-blind><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stress><Structure><T2 DM><T2D><T2DM><Treatment Efficacy><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Weight Loss><Weight Reduction><Work><Yoga><accelerometry><acceptability and feasibility><active followup><activity monitor><activity tracker><adult onset diabetes><adulthood><age 18><age 18 years><behavior change><behavior influence><behavior outcome><behavioral influence><behavioral outcome><bio-markers><biologic marker><biomarker><blood glucose regulation><bodily sensation><body movement><body weight loss><calorie restriction><cardiometabolic><cardiometabolism><chronic disorder><circulatory system><clinical care><cognitive dysfunction><cognitive loss><compulsive eating><compulsive feeding><compulsive overeating><cost estimate><cost estimation><creativity><developmental><diabetes><diabetes education><diabetes management><diabetes mellitus management><diabetes self-care><diabetes self-management><diabetic management><diet and exercise><diet choice><diet intervention><diet preference><diet quality><dietary><dietary choice><dietary preferences><diets><driving><eating habit><efficacy trial><eighteen year old><eighteen years of age><emotion regulation><emotional eater><emotional eating><emotional regulation><enhance healthspan><enroll><evidence base><extend healthspan><extending healthy lifespan><feasibility testing><follow up><follow-up><followed up><followup><food choice><glucose control><glucose homeostasis><glucose regulation><glycemic control><group intervention><health related behavior><healthspan extension><improve healthspan><improved><increase healthspan><insight><intervention efficacy><ketosis resistant diabetes><kidney dysfunction><life span><lifespan><maturity onset diabetes><mindfulness><mindfulness intervention><mindfulness-based intervention><modifiable lifestyle factors><muscle strengthening><nutrient rich food><nutrient rich meal><nutrient-dense meal><pilot study><pilot trial><primary outcome><programs><prolong healthspan><promote healthspan><psychologic><psychological><psychological outcomes><randomisation><randomization><randomized control trial><randomly assigned><renal dysfunction><satiety><self awareness><self knowledge><social role><standard of care><strength training><stress buffering><stress management><stress reduction><therapeutic efficacy><therapy efficacy><tool><two arm RCT><two arm randomized control trial><two arm randomized controlled trial><type 2 DM><type II DM><type two diabetes><wt-loss>

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Anjali Gopalan

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$324,225

FY 2026

Project Title

A pilot trial of an intervention to support initial type 2 diabetes selfmanagement among younger adults with children.

Grant Number:

5R01DK139225-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2025

End Date:

2/29/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT More adults are being diagnosed with type 2 diabetes (T2D) at younger ages and are at increased risk of developing micro- and macrovascular complications occurring earlier in their life courses. The year following T2D diagnosis presents a critical window in which effective behavior change i...

Research Terms

<0-11 years old><21 year old><21 years of age><21+ years old><5 year old><5 years of age><Address><Adherence><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><Behavior><California><Care Givers><Caregivers><Caring><Child><Child Behavior><Child Care><Child Rearing><Child Youth><Children (0-21)><Clinical><Clinical Trials><Complication><Counseling><Data><Diabetes Mellitus><Diagnosis><Diet><Dietitian><Disease Management><Disorder Management><Drugs><Eating><Education><Educational aspects><Electronic Health Record><Elements><Ethnic Origin><Ethnicity><Exercise><Family><Feedback><Food Intake><Foundations><Funding Mechanisms><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Educators><Health behavior><Hemoglobin A(1)><Individual><Infrastructure><Intake><Integrated Delivery of Health Care><Intervention><Intervention Trial><Interventional trial><Interview><Investigators><Ketosis-Resistant Diabetes Mellitus><Life><Life Cycle><Life Cycle Stages><Life Expectancy><Maturity-Onset Diabetes Mellitus><Mediating><Mediator><Medical><Medication><Modeling><Monitor><Motivation><NIDDM><Newly Diagnosed><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nutritional><Outcome><Parenting><Parenting behavior><Parents><Participant><Patient Self-Report><Patients><Persons><Pharmaceutical Preparations><Physical activity><Physiology><Population><Position><Positioning Attribute><Prevention><Prognosis><Provider><Puericulture><Race><Races><Randomization trial><Randomized><Recommendation><Research><Research Personnel><Researchers><Risk><Self Care><Self Efficacy><Self Management><Self-Report><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Survey Instrument><Surveys><System><Systems Theory><T2 DM><T2D><T2DM><Testing><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visit><Waiting Lists><Work><adult onset diabetes><adult youth><adulthood><age 21><age 21 years><age 5><age 5 years><age associated difference><age based difference><age dependent difference><age dependent variation><age difference><age related difference><age related variation><age specific difference><ages><arm><behavior change><childrearing><clinical care><delivered virtually><design><designing><diabetes><diabetes distress><diabetes risk><diabetes self-care><diabetes self-management><diabetes-related distress><diabetes-specific distress><dietary><diets><differ by age><difference across age><difference in age><disease duration><disease length><distress related to diabetes><distress specific to diabetes><drug adherence><drug compliance><drug/agent><effectiveness trial><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><empowerment><experience><five year old><five years of age><future implementation><glucometer><glucose meter><glucose monitor><glycemic control><health related behavior><hemoglobin A1c><illness length><implementation determinants><implementation factors><improved><interactive text messaging><intervention participants><ketosis resistant diabetes><kids><later in life><later life><life course><live text><macrovascular complication><macrovascular disease><maturity onset diabetes><medication adherence><medication compliance><member><new approaches><novel><novel approaches><novel strategies><novel strategy><nutritious><parent><patient population><personal care><pilot trial><post intervention><preference><prevent><preventing><primary outcome><programs><racial><racial background><racial origin><randomisation><randomization><randomized trial><randomly assigned><secondary outcome><self-management program><standard care><standard treatment><sugar><sweetened beverage><twenty-one year old><twenty-one years of age><type 2 DM><type 2 diabetes in children><type II DM><type two diabetes><variation by age><virtual><virtual delivery><virtual group><waitlist><young adult><young adult age><young adulthood><younger age><youngster>

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EMIL Frank COCCARO

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$315,000

FY 2026

Project Title

Development of a Group Emotion-Focused Behavioral Intervention for Diabetes Distress and Glycemic Management in Patients with T2D.

Grant Number:

5R01DK135948-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY T2D is a major public health problem and is currently the 7th leading cause of death in the US. Despite a range of efficacious treatments, less than 50% of patients achieve a glycemic target of A1c < 7.0%, suggesting that this is due to difficulty with following medical regimens to r...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Attention><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Brittle Diabetes Mellitus><Caring><Cause of Death><Characteristics><Complications of Diabetes Mellitus><Conditioning Therapy><Control Groups><Data><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Eligibility><Eligibility Determination><Emotional><Emotions><Enrollment><Foundations><Glycated Hemoglobins><Glycohemoglobin A><Glycosylated Hemoglobin><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><IDDM><Individual><Insulin-Dependent Diabetes Mellitus><Intervention><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Lead><Maturity-Onset Diabetes Mellitus><Measures><Medical><Modification><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Patients><Pb element><Persons><Pilot Projects><Prevalence><Protocol Screening><Public Health><Recommendation><Regimen><Reporting><Risk><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stress><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Testing><Therapeutic><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Work><adult onset diabetes><adulthood><attentional control><barrier to care><barrier to health care><barrier to treatment><behavior intervention><behavioral intervention><compare intervention><comparison intervention><coping><cost><developmental><diabetes><diabetes distress><diabetes self-care><diabetes self-management><diabetes-related distress><diabetes-specific distress><distress related to diabetes><distress specific to diabetes><effectiveness and implementation trial><effectiveness/implementation hybrid trial><effectiveness/implementation trial><efficacious intervention><efficacious therapy><efficacious treatment><emotion regulation><emotional distress><emotional regulation><enroll><experience><feeling distress><feeling upset><group intervention><heavy metal Pb><heavy metal lead><hemoglobin A1c><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><maturity onset diabetes><obstacle to care><obstacle to health care><pilot study><psychosocial stresses><psychosocial stressors><response><retention rate><retention strategy><skills><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes>

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Antoinette M. Moran

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$291,410

FY 2026

Project Title

Diabetes in African Youth: Improving Glucose Time-In-Range

Grant Number:

5R01DK126726-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Despite major improvements, significant disparities in healthcare and outcomes exist in type 1 diabetes (T1D) in low vs high income countries. In our recent study of 68 African youth with T1D, patients were treated and educated by trained pediatric endocrinologists, performed self-monitorin...

Research Terms

<0-11 years old><4 year old><4 years of age><AIDS drugs><AIDS/HIV><Acute><African><Anti-AIDS Agents><Anti-AIDS Drugs><Anti-HIV Agents><Anti-HIV Drugs><Anti-Human Immunodeficiency Virus Agents><Area><Attention><Blinded><Blood Glucose Self-Monitoring><Blood Sugar Self-Monitoring><Brittle Diabetes Mellitus><Caring><Child><Child Youth><Childhood><Children (0-21)><Chronic><Client satisfaction><Clinical><Clinical Research><Clinical Study><Communication><Communities><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Control Groups><Cost Analyses><Cost Analysis><Country><D-Glucose><Data><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Distress><East African><Economic Income><Economical Income><Education><Educational aspects><Educational workshop><Endocrinologist><Ensure><Ethics><Family><GCP standard><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Good Clinical Practice><HIV/AIDS><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care Providers><Health Personnel><Hemoglobin A(1)><Home Blood Glucose Monitoring><Hour><Human><Humulin R><Hypoglycemia><IDDM><Income><Individual><Insulin><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Low income><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Measurement><Measures><Medical><Mentors><Metabolic Control><Minnesota><Modern Man><Monitor><Novolin R><Outcome><Outcome Measure><Patient Education><Patient Instruction><Patient Participation><Patient Satisfaction><Patient Training><Patients><Pediatric Research><Phase><Pilot Projects><Protocol><Protocols documentation><QOL><Quality of life><Randomized, Controlled Trials><Regular Insulin><Research><Research Resources><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Resources><Scanning><Services><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Uganda><Universities><Variant><Variation><Visit><Workshop><Youth><Youth 10-21><age 4><age 4 years><antiAIDS agent><assess cost><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost assessment><cost effective><cost evaluation><data integrity><design><designing><diabetes><diabetes control><diabetes education><diabetes mellitus control><diabetes mellitus therapy><diabetes risk><diabetes therapy><disparity in care><disparity in health care><effective therapy><effective treatment><ethical><evaluate cost><examine cost><experience><four year old><four years of age><health care disparity><health care inequality><health care inequity><health care personnel><health care worker><health provider><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><hemoglobin A1c><high risk><hypoglycemic><hypoglycemic episodes><improved><incomes><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><measurable outcome><medical care providers><medical personnel><outcome measurement><pediatric><pilot study><primary outcome><programs><randomized control trial><randomized, clinical trials><skills><societal costs><test strip><treatment provider><type I diabetes><type one diabetes><youngster><youth age>

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Antoinette M. Moran

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 58/100

Likely hiring

Solid budget

Recent

Active award

$271,939

FY 2026

Project Title

Diabetes in African Youth: Improving Glucose Time-In-Range

Grant Number:

3R01DK126726-05S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Despite major improvements, significant disparities in healthcare and outcomes exist in type 1 diabetes (T1D) in low vs high income countries. In our recent study of 68 African youth with T1D, patients were treated and educated by trained pediatric endocrinologists, performed self-monitorin...

Research Terms

<0-11 years old><4 year old><4 years of age><AIDS drugs><AIDS/HIV><Acute><African><Anti-AIDS Agents><Anti-AIDS Drugs><Anti-HIV Agents><Anti-HIV Drugs><Anti-Human Immunodeficiency Virus Agents><Area><Attention><Blinded><Blood Glucose Self-Monitoring><Blood Sugar Self-Monitoring><Brittle Diabetes Mellitus><Caring><Child><Child Youth><Childhood><Children (0-21)><Chronic><Client satisfaction><Clinical><Clinical Research><Clinical Study><Communication><Communities><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Control Groups><Cost Analyses><Cost Analysis><Country><D-Glucose><Data><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Distress><East African><Economic Income><Economical Income><Education><Educational aspects><Educational workshop><Endocrinologist><Ensure><Ethics><Family><GCP standard><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Good Clinical Practice><HIV/AIDS><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care Providers><Health Personnel><Hemoglobin A(1)><Home Blood Glucose Monitoring><Hour><Human><Humulin R><Hypoglycemia><IDDM><Income><Individual><Insulin><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Low income><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Measurement><Measures><Medical><Mentors><Metabolic Control><Minnesota><Modern Man><Monitor><Novolin R><Outcome><Outcome Measure><Patient Education><Patient Instruction><Patient Participation><Patient Satisfaction><Patient Training><Patients><Pediatric Research><Phase><Pilot Projects><Protocol><Protocols documentation><QOL><Quality of life><Randomized, Controlled Trials><Regular Insulin><Research><Research Resources><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Resources><Scanning><Services><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Uganda><Universities><Variant><Variation><Visit><Workshop><Youth><Youth 10-21><age 4><age 4 years><antiAIDS agent><assess cost><cohort><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost assessment><cost effective><cost evaluation><data integrity><design><designing><diabetes><diabetes control><diabetes education><diabetes mellitus control><diabetes mellitus therapy><diabetes risk><diabetes therapy><disparity in care><disparity in health care><effective therapy><effective treatment><ethical><evaluate cost><examine cost><experience><four year old><four years of age><health care disparity><health care inequality><health care inequity><health care personnel><health care worker><health provider><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><hemoglobin A1c><high risk><hypoglycemic><hypoglycemic episodes><improved><incomes><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><measurable outcome><medical care providers><medical personnel><outcome measurement><pediatric><pilot study><primary outcome><programs><randomized control trial><randomized, clinical trials><skills><societal costs><test strip><treatment provider><type I diabetes><type one diabetes><youngster><youth age>

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Mengyao Tang

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$197,320

FY 2026

Project Title

Optimizing Glycemic Monitoring and Management in People with Type 2 Diabetes and Chronic Kidney Disease

Grant Number:

1K23DK143316-01A1

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2031

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract This K23 proposal focuses on using continuous glucose monitoring (CGM) technology to optimize glycemic monitoring and management in people with type 2 diabetes and chronic kidney disease (CKD), fostering the career development of Mengyao Tang, MD, MPH, as an independent clin...

Research Terms

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Jacqueline Anne Seiglie

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$195,907

FY 2026

Project Title

REACH-Es: Adapting a digital health tool to improve diabetes medication adherence among Latino adults

Grant Number:

5K23DK135798-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2023

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Background: Latino adults have a disproportionate burden of type 2 diabetes and diabetes-related complications. Diabetes medication non-adherence is an important modifiable contributor to suboptimal glycemic management among Latino adults, who are nearly twice as likely to report non-adherence to di...

Research Terms

<2 way SMS><2 way text messaging><2 way texting><21+ years old><Address><Adherence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biometrics><Biometry><Biostatistics><Clinical><Clinical Trials><Communication><Complications of Diabetes Mellitus><Conditioning Therapy><Conduct Clinical Trials><Data><Decrease disparity><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Disparities><Disparity><Drugs><Education><Educational Materials><Educational aspects><Endocrinologist><Epidemiology><Espanol><Evidence based intervention><Feedback><Focus Groups><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care Technology><Health Technology><Hemoglobin A(1)><High Prevalence><Humulin R><Individual><Insulin><Intervention><Interview><Investigators><K23 Award><K23 Mechanism><K23 Program><Ketosis-Resistant Diabetes Mellitus><Language><Latin America><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Lower disparity><Maturity-Onset Diabetes Mellitus><Medication><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Methods><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Novolin R><Outcome><Participant><Patient Self-Report><Patients><Perception><Pharmaceutical Preparations><Physicians><Population><Prevalence><Regular Insulin><Reporting><Research><Research Personnel><Research Training><Researchers><Self Care><Self Efficacy><Self-Report><Slow-Onset Diabetes Mellitus><Spanish><Stable Diabetes Mellitus><Strategic Planning><System><T2 DM><T2D><T2DM><Testing><Text Messaging><Therapeutic><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Work><adult onset diabetes><adulthood><behavior adherence><behavior intervention><behavioral adherence><behavioral intervention><bi-directional SMS><bidirectional SMS><career><clinical relevance><clinically relevant><compare to control><comparison control><compliance behavior><cost><develop therapy><diabetes><diabetes management><diabetes mellitus management><diabetes self-care><diabetes self-management><diabetic management><digital health><disparity reduction><drug adherence><drug compliance><drug/agent><effectiveness and implementation trial><effectiveness/implementation hybrid trial><effectiveness/implementation trial><epidemiologic><epidemiological><ethnic minority><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><health communication><hemoglobin A1c><improved><improved outcome><innovate><innovation><innovative><interactive text messaging><interest><intervention development><intervention refinement><ketosis resistant diabetes><live text><m-Health><mHealth><mHealth therapeutic><mHealth therapy><mHealth treatment><maturity onset diabetes><medication adherence><medication compliance><medication non-adherence><medication nonadherence><mhealth interventions><mitigate disparity><mobile health><mobile health intervention><mobile health therapeutic><mobile health therapy><mobile health treatment><participant engagement><patient centered><patient engagement><patient oriented><patient portal><personal care><reduce disparity><reduction in disparity><response><retention rate><retention strategy><secondary outcome><short message service><sms messaging><social disadvantage><social disparities><social inequality><standard of care><texting><therapy development><tool><treatment development><two way SMS><two way text messaging><two way texting><type 2 DM><type II DM><type two diabetes><usability>

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Persis Commissariat

JOSLIN DIABETES CENTER, BOSTON, MA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$188,784

FY 2026

Project Title

Development of an intervention to target diabetes device use through an identity framework: ACCPTech (Adapt and Commit to CGM and Pump Technology)

Grant Number:

5K23DK137024-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Diabetes technologies to treat type 1 diabetes (T1D) are rapidly advancing: continuous glucose monitors (CGMs) provide data on glucose levels and trends throughout the day without the burden of fingersticks; insulin pumps increase ease of taking insulin without injections; a...

Research Terms

<0-11 years old><18 year old><18 years of age><Address><Adolescent and Young Adult><Affect><Algorithms><Artificial Endocrine Pancreas><Attention><Award><Behavioral><Body Image><Brittle Diabetes Mellitus><Caring><Characteristics><Child><Child Youth><Children (0-21)><Chronic Disease><Chronic Illness><Continuous Glucose Monitor><D-Glucose><Data><Dedications><Development><Devices><Dextrose><Diabetes Mellitus><Dose><Education><Educational aspects><Electronic Health Record><Environment><Fear><Feedback><Fingers><Focus Groups><Foundations><Fright><Future><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Hemoglobin A(1)><Humulin R><Hybrids><IDDM><Injections><Insulin><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intervention><Interview><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Length><Life><Mentors><Mentorship><Modeling><Neighborhoods><Novolin R><Outcome><Pattern><Personal awareness><Persons><Process><Pump><Randomized, Controlled Trials><Regular Insulin><Reporting><Research Personnel><Research Resources><Researchers><Resources><Risk><Sampling><Self Perception><Self image><Self view><Series><Social Network><Social Perception><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Structure><Sudden-Onset Diabetes Mellitus><Survey Instrument><Surveys><System><T1 DM><T1 diabetes><T1D><T1DM><Techniques><Technology><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Work><acceptability and feasibility><adult youth><age 18><age 18 years><age group><body perception><career development><chronic disorder><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><design><designing><develop therapy><developmental><diabetes><diabetes self-care><diabetes self-management><eighteen year old><eighteen years of age><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><engineered pancreas><experience><glucometer><glucose meter><glucose monitor><glucose pump><glycemic control><hemoglobin A1c><improved><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><intervention design><intervention development><intervention mapping><intervention refinement><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><methods to study multiple-level influences><multi-level analysis><multi-level model><multidisciplinary><multilevel analysis><multilevel model><multilevel modeling><novel><patient centered><patient oriented><primary outcome><psychosocial><psychosocial outcome><psychosocial sequelae><randomized control trial><recruit><satisfaction><self awareness><self knowledge><skills><social health determinants><social influence><social stigma><socio-demographic factors><socio-demographics><socio-economic><socio-economically><sociodemographic factors><sociodemographics><socioeconomically><socioeconomics><standard of care><statistical analysis><stigma><technology intervention><technology-based interventions><technology-enabled interventions><technology-focused interventions><therapy design><therapy development><time use><treatment design><treatment development><trend><type I diabetes><type one diabetes><uptake><young adult><young adult age><young adulthood><youngster>

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Amy Elizabeth Noser

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$177,877

FY 2026

Project Title

Technology-Enhanced Adherence to Medication intervention for youth with Type 2 Diabetes (TEAM-T2D)

Grant Number:

1K23DK146162-01

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2031

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Pediatric type 2 diabetes (T2D) is rapidly increasing, with U.S. cases projected to quadruple by 2050. Youth- onset T2D follows a more aggressive disease course than adult-onset, increasing the risk for early microvascular complications. Medication adherence is critical for ...

Research Terms

<12-20 years old><21+ years old><Access to Care><Acute><Address><Adherence><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Adverse Experience><Adverse event><Affect><American><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Belief><Blood Vessels><Brittle Diabetes Mellitus><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Cell Phone><Cellular Phone><Cellular Telephone><Childhood><Childhood diabetes><Clinical Trials><Clinical Trials Design><Collection><Complication><Complications of Diabetes Mellitus><Conditioning Therapy><Data><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diagnosis><Disease><Disorder><Disparities><Disparity><Dose><Drugs><Economics><Educational Materials><Electronics><Enhancement Technology><Ensure><Feedback><Funding><Future><Goals><Health><Health Care Providers><Health Personnel><Health Promotion><Health Services Accessibility><Health behavior><Household><Hyperglycemia><IDDM><Insulin-Dependent Diabetes Mellitus><Interdisciplinary Research><Interdisciplinary Study><Intervention><Intervention Studies><Interview><Investigators><Juvenile-Onset Diabetes Mellitus><K-Awards><K-Series Research Career Programs><K23 Award><K23 Mechanism><K23 Program><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Lead><Leadership><Low income><Maturity-Onset Diabetes Mellitus><Medication><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentorship><Methodology><Methods><Microvascular Dysfunction><Mobile Phones><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><NIDDM><NIH><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Outcome Measure><Parents><Patients><Pb element><Pharmaceutical Preparations><Population><Position><Positioning Attribute><Process><Randomized, Controlled Trials><Regimen><Research><Research Career Program><Research Methodology><Research Methods><Research Personnel><Researchers><Risk><Risk Reduction><Role><Salutogenesis><Sampling><Self Efficacy><Slow-Onset Diabetes Mellitus><Social support><Stable Diabetes Mellitus><Sudden-Onset Diabetes Mellitus><Survey Instrument><Surveys><System><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Testing><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Work><Youth><Youth 10-21><acceptability and feasibility><access to health services><access to services><access to treatment><accessibility to health services><adolescence (12-20)><adult onset diabetes><adulthood><availability of services><behavior adherence><behavior intervention><behavioral adherence><behavioral intervention><care access><career><compliance behavior><design><designing><develop therapy><developmental><diabetes><diabetes distress><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes-related distress><diabetes-specific distress><digital><digital tool><digital toolkit><discrimination based on race><discrimination due to race><distress related to diabetes><distress specific to diabetes><drug adherence><drug compliance><drug/agent><economic><effectiveness and implementation trial><effectiveness/implementation hybrid trial><effectiveness/implementation trial><electronic><electronic device><emerging adulthood><evidence base><experience><glycemic control><health care personnel><health care settings><health care worker><health provider><health related behavior><health service access><health services availability><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><heavy metal Pb><heavy metal lead><hyperglycemic><iPhone><improved><innovate><innovation><innovative><innovative technologies><insulin dependent diabetes><insulin dependent type 1><intervention development><intervention mapping><intervention research><interventional research><interventional study><interventions research><juvenile><juvenile diabetes><juvenile diabetes mellitus><juvenile human><ketosis prone diabetes><ketosis resistant diabetes><marginalized group><marginalized individual><marginalized people><marginalized population><maturity onset diabetes><measurable outcome><medical care providers><medical personnel><medication adherence><medication compliance><microvascular complications><microvascular disease><monitoring device><natives><new technology><novel technologies><outcome measurement><parent><participant engagement><patient engagement><pediatric><pediatric diabetes><pill><pilot test><primary outcome><promoting health><psychosocial outcome><psychosocial sequelae><race discrimination><race-based discrimination><race-related discrimination><racial discrimination><randomized control trial><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><research and methods><risk-reducing><secondary outcome><service availability><smart phone><smartphone><social culture><social health determinants><social role><social stigma><social support network><socio-cultural><sociocultural><stigma><tailored text messaging><technology intervention><technology-based interventions><technology-enabled interventions><technology-focused interventions><telehealth><therapy development><tool><treatment access><treatment adherence><treatment compliance><treatment development><treatment provider><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><vascular><youth age>

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Christopher Jesus Gonzalez

WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$170,072

FY 2026

Project Title

Developing and Piloting FUERTE: Federally qUalified health centers Engaging Hispanic men at Risk of DiabeTEs

Grant Number:

5K23DK139410-02

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
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Project Abstract

Diabetes and diabetes-related complications are disproportionately more prevalent among Hispanic men. The Diabetes Prevention Program (DPP) is an intensive lifestyle intervention that effectively reduces the risk of diabetes; however, Hispanic men are relatively underrepresented in the program and...

Research Terms

<21+ years old><Address><Adoption><Adult><Adult Human><Affect><Amputation><Assess implementation><Award><Body Weight Changes><Body Weight decreased><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caucasian male><Caucasian men><Cessation of life><Collaborations><Complications of Diabetes Mellitus><Data><Death><Decrease health disparities><Development><Development and Research><Diabetes Complications><Diabetes Mellitus><Diabetes prevention><Diabetes-Related Complications><Diabetic Complications><Diminished Vision><Disparities><Disparity><Doctor of Philosophy><Effectiveness><Eligibility><Eligibility Determination><Enrollment><Environment><Federally Qualified Health Center><Feedback><Focus Groups><Foundations><Funding><Future><Goals><Health><Health Services Evaluation><Health Services Research><Health disparity mitigation><Health disparity reduction><High Prevalence><Hispanic><Hispanic male><Hispanic men><Hybrids><Implementation assessment><Internal Medicine><Intervention><Interview><Investigators><K-Awards><K-Series Research Career Programs><K23 Award><K23 Mechanism><K23 Program><Kidney Failure><Kidney Insufficiency><Knowledge><Knowledge acquisition><Lead><Low Vision><Lower Extremity><Lower Limb><Lower health disparities><Maintenance><Medical Care Research><Membrum inferius><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Mitigate health disparities><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><New York><New York City><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Partial Sight><Patients><Pb element><Persons><Ph.D.><PhD><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative intervention><Prevention Research><Primary Care><Protocol Screening><Provider><Qualifying><Qualitative Methods><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Recommendation><Reduce health disparities><Reduced Vision><Renal Failure><Renal Insufficiency><Research><Research Career Program><Research Design><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Risk Reduction><Study Type><Subnormal Vision><Testing><Training><Training Support><Translational Research><Translational Science><Translations><Visual impairment><Weight Change><Weight Loss><Weight Reduction><Work><adulthood><body weight loss><cardiometabolic><cardiometabolism><career><career development><cost><design><designing><developmental><diabetes><diabetes prevention program><diabetes risk><disparity in health><effective intervention><effectiveness and implementation trial><effectiveness/implementation hybrid trial><effectiveness/implementation trial><enroll><evaluate implementation><evaluation of implementation><evidence base><experience><health assessment><health disparity><heavy metal Pb><heavy metal lead><high risk><hispanic community><implementation evaluation><implementation science><implementation strategy><implementation trial><improved><intervention design><intervention for prevention><life style intervention><lifestyle intervention><medical college><medical schools><multi-site trial><multidisciplinary><multisite trial><novel><outreach><patient centered><patient oriented><peer support><pilot test><post-doctoral training><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary care practice><programs><qualitative reasoning><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><research and development><risk-reducing><school of medicine><services research><skills><strategies for implementation><study design><theories><therapy design><translation><translation research><translational investigation><treatment design><user centered design><vision impairment><visually impaired><white male><white men><wt-loss>

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Yoseob Joseph Hwang

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$169,927

FY 2026

Project Title

Evaluating Comparative Effectiveness of Glucose-lowering Therapy in People with HIV and Type 2 Diabetes

Grant Number:

1K08DK146757-01

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2031

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY In the era of modern antiretroviral therapy (ART), cardiometabolic diseases have become a leading cause of morbidity and mortality among people with HIV (PWH). Type 2 diabetes, a major contributor to cardiovascular and kidney disease, now affects approximately one in five PWH. PWH fa...

Research Terms

<21+ years old><AIDS><AIDS Virus><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Address><Adipose tissue><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Advanced HIV><Affect><Age><Agonist><American><Analgesic Management><Attenuated><Award><Canada><Cardiac infarction><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Chronic><Clinical><Cluster Analyses><Cluster Analysis><Collaborations><D-Glucose><Data><Development><Dextrose><Diabetes Mellitus><Dimethylbiguanidine><Dimethylguanylguanidine><Dipeptidyl Aminopeptidases><Dipeptidyl Peptidases><Dipeptidylpeptide Hydrolases><Drug Therapy><Drugs><Dysfunction><ESKD><ESRD><Effectiveness><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Epidemiologic Methodology><Epidemiologic Methods><Epidemiologic research methodology><Epidemiologic research methods><Epidemiological Methods><Epidemiological Techniques><Epidemiology><Exposure to><Face><Fatty Tissue><Functional disorder><GLP-1 receptor><GLP-I receptor><Glomerular Filtration Rate><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><HIV><HIV Infections><HIV individuals><HIV infected individuals><HIV infected persons><HIV people><HIV positive individuals><HIV positive people><HIV viral infection><HIV virus infection><HIV-1 infection><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Heart Vascular><Hemoglobin A(1)><Heterogeneity><Human Immunodeficiency Viruses><Individual><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Inflammation><Insurance><Insurance Coverage><Insurance Status><Integrase Inhibitors><Internal Medicine><Investigators><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Urinary System><Knowledge><LAV-HTLV-III><Laboratories><Lymphadenopathy-Associated Virus><Machine Learning><Maturity-Onset Diabetes Mellitus><Medication><Medication Management><Mentors><Metabolic><Metformin><Methods><Methods Epidemiology><Methods in epidemiology><Modernization><Modification><Morbidity><Myocardial Infarct><Myocardial Infarction><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><Nephropathy><Nephrotoxic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Outcome><PLWH><PWH><Pattern><Pharmaceutical Epidemiology><Pharmaceutical Preparations><Pharmacoepidemiology><Pharmacologic Management><Pharmacological Treatment><Pharmacotherapy><Physicians><Physiopathology><Population><Race><Races><Regimen><Renal Disease><Renal function><Research><Research Personnel><Researchers><SGLT 2 inhibitor><SGLT2i><Selection for Treatments><Severe HIV Disease><Site><Slow-Onset Diabetes Mellitus><Sodium glucose co-transporter 2 inhibitor><Stable Diabetes Mellitus><Structural Models><Subgroup><Sulfonylurea Compounds><T2 DM><T2D><T2DM><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><United States><Universities><Virus-HIV><Work><adipose><adiposity><adult onset diabetes><adulthood><ages><antiretroviral therapy><antiretroviral treatment><attenuate><attenuates><cardiac infarct><cardiometabolic><cardiometabolism><cardiovascular disorder><career><circulatory system><clinical care><clinical diagnosis><clinical research site><clinical site><co-exposures><co-morbid><co-morbidity><co-occurring exposure><cohort><combined exposure><comorbidity><comparative effectiveness><compare effectiveness><compare treatment><complex exposure><concurrent exposure><coronary attack><coronary infarct><coronary infarction><corpulence><data collected in real world><demographics><design><designing><developmental><diabetes><diabetes management><diabetes mellitus management><diabetic management><doubt><drug epidemiology><drug intervention><drug treatment><drug/agent><epidemiologic><epidemiological><exposure mixture><faces><facial><fat metabolism><glucagon-like peptide-1 receptor><glucose metabolism><glycemic control><heart attack><heart infarct><heart infarction><hemoglobin A1c><human immunodeficiency virus infection><improved><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><inhibitor><innovate><innovation><innovative><ketosis resistant diabetes><kidney disorder><kidney function><kidney toxicity><lipid metabolism><machine based learning><machine learning based method><machine learning method><machine learning methodologies><maturity onset diabetes><medication therapy management><mixed exposure><mortality><multidisciplinary><nephrotoxicity><pathophysiology><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><pharmaceutical intervention><pharmacoepidemiologic><pharmacoepidemiological><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><racial><racial background><racial origin><real world data><real world evidence><renal><renal disorder><response><selection of treatment><simultaneous exposures><sulfonylurea><therapy selection><time to event><time to occurrence><treatment comparison><treatment selection><type 2 DM><type II DM><type two diabetes><uptake><white adipose tissue><yellow adipose tissue>

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Estelle Marla Everett

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$166,013

FY 2026

Project Title

Hybrid Closed Loop Insulin Pump use in Poorly Controlled Type 1 Diabetes

Grant Number:

5K23DK132482-05

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/19/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
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Project Abstract

Project Summary/Abstract This career development award will establish me (Dr. Estelle Everett MD, MHS), as an independent investigator focused on evaluating and addressing disparities in management and outcomes in vulnerable patient populations with type 1 diabetes (T1D). This K23 award will provide...

Research Terms

<21+ years old><Achievement><Achievement Attainment><Address><Adult><Adult Human><Algorithms><American><Area><Award><Blood Glucose Self-Monitoring><Blood Sugar Self-Monitoring><Blood Vessels><Brittle Diabetes Mellitus><Bypass><Calibration><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Cessation of life><Clinical><Clinical Trials><Clinical Trials Design><Complex><Computerized Medical Record><Continuous Glucose Monitor><County><Data><Data Analyses><Data Analysis><Data Collection><Death><Development><Diabetes Mellitus><Disparities><Disparity><Documentation><Dose><Education><Educational aspects><Electronic Health Record><Electronic Medical Record><Endocrinologist><Enrollment><Evaluation><Exclusion><Fingers><Funding><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Care Systems><Health Services><Health system><Hemoglobin><Hemoglobin A(1)><Home Blood Glucose Monitoring><Humulin R><Hybrids><IDDM><Injections><Insulin><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intervention><Investigators><Juvenile-Onset Diabetes Mellitus><K-Awards><K-Series Research Career Programs><K23 Award><K23 Mechanism><K23 Program><Ketosis-Prone Diabetes Mellitus><Knowledge><Los Angeles><Medical><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Methods><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Natural Language Processing><Novolin R><Outcome><Paper><Patient Care><Patient Care Delivery><Patients><Population><Position><Positioning Attribute><Principal Investigator><Publishing><Pump><QOL improvement><Randomized, Controlled Trials><Recommendation><Regular Insulin><Research><Research Career Program><Research Personnel><Research Training><Researchers><Risk><Self Management><Series><Socio-economic status><Socioeconomic Status><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Vulnerable Populations><access disparities><accessibility disparities><adulthood><assess effectiveness><basal insulin><care burden><care for patients><care of patients><caring for patients><clinical care><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><data interpretation><design><designing><determine effectiveness><determine efficacy><developmental><diabetes><diabetes control><diabetes management><diabetes mellitus control><diabetes mellitus management><diabetic management><disparities in access><effectiveness assessment><effectiveness evaluation><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><ethnic minority><evaluate effectiveness><evaluate efficacy><examine effectiveness><examine efficacy><experience><glucometer><glucose meter><glucose monitor><glycemic control><health care settings><hemoglobin A1c><high risk><high risk group><high risk individual><high risk people><high risk population><improved><improved outcome><improvements in QOL><improvements in quality of life><inadequate health literacy><inequality in access><inequity in access><inequity in accessibility><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><interest><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><low SES><low health literacy><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><monitoring device><natural language understanding><new technology><novel><novel technologies><patient centered><patient oriented><patient population><poor health literacy><quality of life improvement><racial minority><randomized control trial><real time monitoring><realtime monitoring><reduced health literacy><safety net><satisfaction><sensor><skills><socio-economic position><socioeconomic position><type I diabetes><type one diabetes><vascular><vulnerable group><vulnerable individual><vulnerable people>

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Amanda Candice Leiter

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$166,002

FY 2026

Project Title

Optimizing diabetes treatment strategies in complex comorbidity

Grant Number:

5K08DK137022-04

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2024

End Date:

1/31/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Breast cancer (BC) survivors are the largest cancer survivor group (~4 million in the US) given improvements in screening and long-term BC survival. While BC progression is a concern in this group, many BC survivors die of comorbid illness. Specifically, type 2 diabetes (T2D...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Age><Agonist><Big Data><BigData><Biometrics><Biometry><Biostatistics><Breast Cancer><Breast Cancer Treatment><Breast Cancer survivor><Breast Cancer therapy><CVD prevention><Cancer Survivor><Cancer Survivorship><Cancer Treatment><Cancers><Cardiac Toxicity><Cardiotoxic><Cardiotoxicity><Cardiovascular Diseases><Cause of Death><Characteristics><Clinical><Clinical Data><Communication><Complex><Complications of Diabetes Mellitus><Country><Data><Data Set><Development><Development and Research><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Dimethylbiguanidine><Dimethylguanylguanidine><Drugs><Endocrinologist><Epidemiologic Methodology><Epidemiologic Methods><Epidemiologic research methodology><Epidemiologic research methods><Epidemiological Methods><Epidemiological Techniques><Epidemiology><Exclusion><GLP-1 receptor><GLP-I receptor><Goals><Grant><Guidelines><Hemoglobin><Humulin R><Hypoglycemia><Insulin><Investigators><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Urinary System><Knowledge><Leadership><Life Expectancy><Link><Malignant Breast Neoplasm><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Medication><Mentorship><Metformin><Methods Epidemiology><Methods in epidemiology><Modeling><Morbidity><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><Natural History><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Outcome><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pharmaceutical Preparations><Physicians><Population><Prevalence><Prognosis><QALY><QOL><Quality of life><Quality-Adjusted Life Expectancy><Quality-Adjusted Life Years><R & D><R&D><Randomized, Controlled Trials><Recommendation><Recurrent Malignant Neoplasm><Recurrent Malignant Tumor><Regimen><Regular Insulin><Renal Disease><Research><Research Personnel><Researchers><Risk><SGLT 2 inhibitor><SGLT2i><Safety><Slow-Onset Diabetes Mellitus><Sodium glucose co-transporter 2 inhibitor><Source><Stable Diabetes Mellitus><Statistical Methods><Survivors><T2 DM><T2D><T2DM><Techniques><Training><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><Writing><adult onset diabetes><adulthood><ages><anti-cancer therapy><breast cancer progression><breast cancer survival><cancer recurrence><cancer survivor care><cancer survivorship care><cancer therapy><cancer-directed therapy><cardiac disease prevention><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><career><career development><chemotherapy><co-morbid><co-morbidity><comorbidity><comparative effectiveness><compare treatment><competing risk><data diversity><data imputation><death risk><developmental><diabetes><diabetes management><diabetes mellitus management><diabetic management><diverse data><doubt><drug/agent><effective therapy><effective treatment><epidemiologic><epidemiological><experience><glucagon-like peptide-1 receptor><glycemic control><hypoglycemic><hypoglycemic episodes><improved><imputation method><in silico><innovate><innovation><innovative><ketosis resistant diabetes><kidney disorder><malignancy><malignant breast tumor><maturity onset diabetes><medical college><medical schools><model-based simulation><models and simulation><mortality><mortality risk><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><over-treatment><overtreatment><patient oriented outcomes><randomized control trial><renal><renal disorder><research and development><school of medicine><screening><screenings><shared decision making><skills><statistic methods><success><translation><treatment comparison><treatment strategy><trial comparing><type 2 DM><type II DM><type two diabetes>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jesse Allen Goodrich

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Good lead · 56/100

Training-friendly

Very recent

Active award

Career award

$162,783

FY 2026

Project Title

PFAS and Diabetic Kidney Disease in Young Onset Type 2 Diabetes: Emerging Risk Factors and Underlying Mechanisms

Grant Number:

5K01ES036193-03

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/16/2024

End Date:

3/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY / ABSTRACT Diabetic kidney disease (DKD) develops in more than 50% of youth with type 2 diabetes (T2D) as they transition to young adulthood. Early identification of youth at risk of DKD, either due to environmental or biological factors, has the potential to inform clinical care and...

Research Terms

<(TNF)-α><12-20 years old><21+ years old><Acceleration><Adolescence><Adolescent><Adolescent Youth><Adolescent and Young Adult><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Advisory Committees><Albuminuria><Amino Acids><Archives><Aromatic Amino Acids><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Beta Cell><Biologic Factor><Biological><Biological Factors><Blood><Blood Plasma><Blood Reticuloendothelial System><Brittle Diabetes Mellitus><Cachectin><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Cessation of life><Chemicals><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Data><Critical Paths><Critical Pathways><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Death><Development><Dextrose><Diabetic Kidney Disease><Diabetic Nephropathy><Dialysis><Dialysis procedure><Disease><Disease Frequency Surveys><Disease Progression><Disorder><Early identification><Environmental Exposure><Environmental Factor><Environmental Health><Environmental Health Science><Environmental Risk Factor><Environmental Toxin><Epidemiological data><Epidemiology data><Exposure Assessment><Exposure to><Future><Glucose><Goals><Groups at risk><HPGF><Health><Hepatocyte-Stimulating Factor><Hybridoma Growth Factor><IDDM><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Impairment><Incidence><Individual><Industrial Product><Inflammation><Inflammatory><Injury to Kidney><Instruction><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Interleukin-6><Intervention><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Kidney Failure><Kidney Insufficiency><Lesion><Link><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><MGI-2><Macrophage-Derived TNF><Manuscripts><Maturity-Onset Diabetes Mellitus><Measures><Mentors><Mentorship><Methods><Molecular Epidemiology><Monocyte-Derived TNF><Multiomic Data><Myeloid Differentiation-Inducing Protein><NIDDM><NIEHS><National Institute of Environmental Health Sciences><Newly Diagnosed><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><PFAS><Participant><Pathway interactions><People at risk><Persons at risk><Plasma><Plasma Serum><Plasmacytoma Growth Factor><Poly-fluoroalkyl substances><Population><Populations at Risk><Prevalence><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Prospective Studies><Proteins><Proteomics><Proxy><Puberty><R-Series Research Projects><R01 Mechanism><R01 Program><Regulation><Renal Failure><Renal Insufficiency><Renal function><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Role><Sampling><Site><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Subcellular Process><Subgroup><Sudden-Onset Diabetes Mellitus><Survival Analyses><Survival Analysis><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Task Forces><Testing><Therapeutic Intervention><Toxic Environmental Agents><Toxic Environmental Substances><Toxic effect><Toxicities><Toxin><Training><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States><Uremia><Visit><Youth><Youth 10-21><adolescence (12-20)><adult onset diabetes><adult youth><adulthood><advisory team><amino acid metabolism><aminoacid><analytical method><analyzing longitudinal><biologic><blood glucose regulation><cartilage link protein><chronic kidney disease><clinical care><conference><consumer product><convention><cross-sectional research study><data integration><developmental><dialysis therapy><disease risk><disease subgroups><disease subtype><disorder risk><disorder subtype><early onset><effective therapy><effective treatment><environmental risk><environmental toxicant><epidemiologic data><exposure analysis><exposure evaluation><exposure measurement><exposure profiling><exposure survey><exposure to environmental agents><exposure to environmental factors><exposure to environmental stimuli><exposure to environmental substances><glucose control><glucose homeostasis><glucose regulation><high risk><impaired glucose tolerance><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><interferon beta 2><intervention therapy><juvenile><juvenile diabetes><juvenile diabetes mellitus><juvenile human><ketosis prone diabetes><ketosis resistant diabetes><kidney function><kidney injury><life span><life style intervention><life-time risk><lifespan><lifestyle intervention><lifetime risk><link protein><long-term study><longitudinal analysis><longitudinal outcome studies><longitudinal research study><malleable risk><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><modifiable risk><multiomics><multiple omic data><multiple omics><novel><panomics><pathway><perfluorinated alkyl substances><perfluoroalkyl substances><perfluoroalkylated substances><personalized health intervention><personalized intervention><polyfluorinated alkyl substances><polyfluoroalkyl substances><precision interventions><premature><prematurity><prevent><preventing><prospective><prospective research study><prospective survey><recruit><renal injury><social role><summit><symposia><symposium><therapeutic biomarker><therapeutic marker><therapeutic target><type 1 and type 2 diabetes><type 2 DM><type I and type II diabetes><type I diabetes><type II DM><type one diabetes><type two diabetes><uremia of renal origin><young adult><young adult age><young adulthood><youth age><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Heikki Hyöty

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 56/100

Likely hiring

Very recent

Active award

$145,543

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Richard E Lloyd

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 56/100

Likely hiring

Very recent

Active award

$145,543

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kristian F Lynch

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 56/100

Likely hiring

Very recent

Active award

$145,543

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eoin McKinney

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 56/100

Likely hiring

Very recent

Active award

$145,543

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

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Joseph Frank Petrosino

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 56/100

Likely hiring

Very recent

Active award

$145,543

FY 2026

Project Title

Virome and Immune Responses associated with IA and Type 1 Diabetes

Grant Number:

3R01DK138372-03S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2024

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The goal of this project is to integrate analysis of viral and immune responses using white blood cells, nasal swabs and plasma from 450 children previously collected from the prospective cohort TEDDY study, to build upon previous TEDDY findings that strongly implicated prolonged infections with Typ...

Research Terms

<0-11 years old><15 year old><15 years of age><3 year old><3 years of age><6 year old><6 years of age><Acute><Adenoviridae Infections><Adenovirus Infections><Age><Age of Onset><Anti-viral Response><Antibodies><Antibody Response><Antigen Receptors><Antigens><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><Birth><Blood Plasma><Blood Sample><Blood leukocyte><Blood specimen><Brittle Diabetes Mellitus><CC-1><CC-3><CCL14><CCL14 gene><CKb1><Celiac Disease><Celiac Sprue><Cell Body><Cells><Chemokine (C-C Motif) Ligand 14><Chemokine CC-1><Chemokine CC-1/CC-3><Chemokine CC-3><Child><Child Youth><Childhood diabetes><Children (0-21)><Coeliac Disease><Collection><Complex><Country><Data><Detection><Development><Diabetes Mellitus><Diagnostic><Disease><Disease Outcome><Disorder><Enterovirus><Enterovirus Infections><Exposure to><Feces><Finland><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><Genes><Genetic><Genetic Markers><Genetic Risk><Genetic Transcription><Genomics><Genotype><Germany><Global Change><Gluten Enteropathy><Gluten-Sensitive Enteropathy><Goals><HCC-1><HCC-1/HCC-3><HCC-3><Humoral Immunities><IDDM><Immune><Immune response><Immunes><Immunity><Infection><Infectious Agent><Innate Immunity><Insulin-Dependent Diabetes Mellitus><International><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Leukocytes><Leukocytes Reticuloendothelial System><Link><MCIF><Marrow leukocyte><Maternal antibody><Modeling><Molecular><NCC-2><NCC2><Native Immunity><Natural Immunity><Neighborhoods><Nested Case-Control Study><Non-Specific Immunity><Nonspecific Immunity><Nontropical Sprue><PBMC><Parturition><Pattern><Peripheral Blood Mononuclear Cell><Plasma><Plasma Serum><Population><Preventative intervention><Preventative strategy><Prevention strategy><Preventive strategy><Prospective cohort><Prospective, cohort study><Quantitative RTPCR><Quantitative Reverse Transcriptase PCR><RNA Expression><Recombinants><Reticuloendothelial System, Serum, Plasma><Risk><Role><SCYA14><SCYL2><SEQ-AN><SY14><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Series><Serology><Serology test><Serotyping><Single cell seq><Source><Sudden-Onset Diabetes Mellitus><Sweden><System><T1 DM><T1 diabetes><T1D><T1DM><Time><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Vaccination><Vaccines><Viral><Viral Antibodies><Viral Diseases><Virus><Virus Diseases><White Blood Cells><White Cell><Whole Blood><Work><acute infection><age 15><age 15 years><age 3><age 3 years><age 6><age 6 years><ages><allelic variant><analyze gene expression><anti-viral antibody><antibody-based immunity><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><beta cell development><biomarker identification><case control><case-controlled><clinical center><cohort><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><disease risk><disorder risk><early childhood><endocrine pancreas development><fifteen year old><fifteen years of age><gene biomarker><gene expression analysis><gene expression assay><gene expression biomarker><gene marker><gene signature biomarker><genetic biomarker><genetic variant><genomic data><genomic dataset><genomic variant><host response><identification of biomarkers><identification of new biomarkers><idiopathic steatorrhea><immune system response><immunogen><immunoresponse><infectious organism><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><intervention for prevention><islet><islet autoimmunity><islet cell autoimmunity><islet development><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><marker identification><multiomics><multiple omics><nasal swab><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><panomics><pediatric diabetes><peripheral blood><population based><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><progression biomarker><progression marker><prospective><protein expression><qRTPCR><response><self reactive antibody><seroconversion><serology assay><single cell analysis><single cell next generation sequencing><single cell sequencing><six year old><six years of age><social role><stool><three year old><three years of age><transcriptional profiling><treatment strategy><type I diabetes><type one diabetes><viral infection><viral microbiome><virome><virus infection><virus-induced disease><white blood cell><white blood corpuscle><youngster>

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Dunli Wu

ASIAN COMMUNITY HEALTH COALITION, PHILADELPHIA, PA

Good lead · 54/100

Large award

Very recent

Active award

$1,499,980

FY 2026

Project Title

Community-Led Health Impact Project (CLIP)

Grant Number:

3OT2OD035669-01S3

Activity Code:

OT2

Mechanism:

Other

Agency:

NIH

Start Date:

9/18/2023

End Date:

9/17/2028

Why this may be worth a closer look

• Large budget suggests more room for personnel or project growth.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

1.- Modified Project Summary/Abstract Section Community-Led Health Impact Project (CLIP) Over 38 million Americans live with type 2 diabetes and more than 122 million have hypertension. Asian Americans face elevated risks for both conditions despite relatively low obesity rates. Our community need...

Research Terms

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Luke Norton

UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, SAN ANTONIO, TX

Good lead · 52/100

Likely hiring

Solid budget

Active award

$489,396

FY 2026

Project Title

The Regulation of Hepatic Metabolic Zonation by the Diabetes Gene TCF7L2

Grant Number:

5R01DK128247-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT The mammalian liver consists of functional units called lobules, which are spatially separated into zones relative to the portal triad and central vein. Each zone contains hepatocytes with distinct functions that differentially impact metabolic processes. This spatial division of labor in l...

Research Terms

<21+ years old><ATAC sequencing><ATAC-seq><ATACseq><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Ammonia><Architecture><Assay for Transposase-Accessible Chromatin using sequencing><Autoregulation><Basal Transcription Factor><Basal transcription factor genes><Beta Cadherin-Associated Protein><Beta-1 Catenin><Body Tissues><CUL-2><Candidate Disease Gene><Candidate Gene><Catabolism><Cell Nucleus><Central Vein><Cirrhosis><Clinical><Couples><D-Glucose><Data><Defect><Development><Dextrose><Diabetes Mellitus><Disease><Disorder><Drug Metabolic Detoxication><Drug Metabolic Detoxification><Engineering / Architecture><Enzyme Gene><Enzymes><Equilibrium><Fibrosis><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Polymorphism><Genetic Transcription><Genomics><Gln><Glucose><Glutamate Ammonia Ligase (ADP)><Glutamate-Ammonia Ligase><Glutamates><Glutamine><Glutamine Synthetase><HMG-1 Domain><HMG-1-Box Domain><HMG-Box><HMG-Box Domains><Hepatic><Hepatic Cells><Hepatic Disorder><Hepatic Parenchymal Cell><Hepatocarcinoma><Hepatocellular Carcinoma><Hepatocellular cancer><Hepatocyte><Hepatoma><High Mobility Group-Box Domains><Homeostasis><Human><Intermediary Metabolism><Ketosis-Resistant Diabetes Mellitus><L-Glutamate><L-Glutamine><Link><Lipids><Liver><Liver Cells><Liver Cells Carcinoma><Liver Fibrosis><Liver diseases><Lobular><Lobule><Maintenance><Maturity-Onset Diabetes Mellitus><Mediating><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Drug Detoxications><Metabolic Pathway><Metabolic Processes><Metabolic dysfunction><Metabolism><Metabolism of Toxic Agents><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Murine><Mus><NAFLD><NASH><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nucleus><PRO2286><Pathologic Processes><Pathological Processes><Pathway interactions><Peripheral><Physiologic><Physiological><Physiological Homeostasis><Play><Population><Portal triad><Prevalence><Primary carcinoma of the liver cells><Proteins><Public Health><Publishing><Q Levoglutamide><Q. Levoglutamide><RNA Expression><Regulation><Rodent><Rodent Model><Rodentia><Rodents Mammals><Role><Signal Pathway><Single-Nucleus Sequencing><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><T cell factor 4><T cell transcription factor 4><T-Cell-Specific Transcription Factor 4><T2 DM><T2D><T2DM><TCF-4><TCF4><TCF7L2><TCF7L2 gene><Tcf4 transcription factor><Tcf712 transcription factor><Techniques><Testing><Thesaurismosis><Tissues><Transcription><Transcription Factor 7-Like 2><Transcription Factor Proto-Oncogene><Transcription factor genes><Transcriptional Control><Transcriptional Regulation><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><adult onset diabetes><adulthood><amino acid metabolism><assay for transposase accessible chromatin followed by sequencing><assay for transposase accessible chromatin seq><assay for transposase accessible chromatin sequencing><assay for transposase-accessible chromatin with sequencing><balance><balance function><beta cat><beta catenin><cirrhotic><design><designing><detoxification><developmental><diabetes><dietary><experiment><experimental research><experimental study><experiments><fat metabolism><fibrogenesis><fibrotic liver><global gene expression><global transcription profile><glucose metabolism><glutamate synthetase><glutamatergic><glutamine synthase><hepatic body system><hepatic disease><hepatic fibrosis><hepatic organ system><hepatopathy><hormonal regulation><hormone regulation><human model><in vivo><ketosis resistant diabetes><lipid metabolism><liver carcinoma><liver disorder><maturity onset diabetes><metabolism disorder><model of human><mouse model><multiomics><multiple omics><murine model><non-alcohol fatty liver disease><non-alcohol induced steatohepatitis><non-alcoholic fatty liver disease><non-alcoholic liver disease><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic fatty liver disease><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><novel><panomics><pathway><polymorphism><sNuc-Seq><single nucleus RNA-sequencing><single nucleus seq><single-nucleus RNA-seq><snRNA sequencing><snRNA-seq><social role><spatial and temporal><spatial temporal><spatiotemporal><tool><transcription factor><transcriptome><treatment strategy><type 2 DM><type II DM><type two diabetes><β-catenin>

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Kasia Joanna Lipska

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 52/100

Likely hiring

Solid budget

Active award

$468,180

FY 2026

Project Title

Addressing Social Determinants of Health in Young Adults with Type 1 Diabetes Through Comprehensive Assessment, Responsiveness, and Engagement (T1CARE)

Grant Number:

5R01DK139558-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/28/2025

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Adverse social determinants of health constitute major barriers to type 1 diabetes (T1D) management and drive disparities in diabetes outcomes. Young adults with T1D tend to have the worst glycemic control levels of all age groups, with Black and Hispanic young adults experiencing the highe...

Research Terms

<21+ years old><Accountability><Address><Adult><Adult Human><Adverse Experience><Adverse event><Affect><Black><Black race><Brittle Diabetes Mellitus><Caring><Cell Communication and Signaling><Cell Signaling><Childhood><Classification><Clinical><Collection><Communities><Community Health><Community Health Aides><Complex><Complication><Crowding><Data><Decrease health disparities><Diabetes Mellitus><Disparities><Disparity><Dose><Economic Factors><Economic Income><Economical Factors><Economical Income><Effectiveness><Endocrine><Endocrinologist><Ensure><Environmental Factor><Environmental Risk Factor><Ethnic Origin><Ethnicity><Face><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Systems><Health Food><Health disparity mitigation><Health disparity reduction><Hemoglobin A(1)><Hispanic><Humulin R><Hybrids><IDDM><Income><Individual><Insulin><Insulin-Dependent Diabetes Mellitus><Insurance Coverage><Insurance Status><Intervention><Intracellular Communication and Signaling><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Life><Link><Lower health disparities><Measures><Medical><Mitigate health disparities><Modeling><Novolin R><Nutritious food><Outcome><Outcome Measure><Participant><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Persons><Population><Procedures><Process><QOL><Quality of life><Race><Races><Randomization trial><Randomized><Reduce health disparities><Regular Insulin><Reporting><Resolution><Risk Factors><SES disparity><Services><Signal Transduction><Signal Transduction Systems><Signaling><Social support><Standardization><Sudden-Onset Diabetes Mellitus><Systematics><T1 DM><T1 diabetes><T1D><T1DM><Technology><Testing><Transportation><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Underserved Population><Work><adult youth><adulthood><age group><analog><barrier to care><barrier to health care><barrier to treatment><biological signal transduction><care as usual><clinical care><clinical practice><community advisory board><community advisory committee><community advisory panel><community based organizations><community engaged participatory research><community engaged research><community health worker><community organizations><community partnered research><community-based health><community-engaged study><community-partnered study><diabetes><diabetes distress><diabetes management><diabetes mellitus management><diabetes-related distress><diabetes-specific distress><diabetic management><disparity in health><distress related to diabetes><distress specific to diabetes><effectiveness and implementation trial><effectiveness/implementation hybrid trial><effectiveness/implementation trial><environmental risk><experience><faces><facial><feasibility testing><food insecure><food insecurity><food scarcity><glycemic control><health disparity><healthy food><hemoglobin A1c><housing insecurity><housing instability><implementation science><improved><improved outcome><incomes><innovate><innovation><innovative><insecure housing><instably housed><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><lack of stable housing><low food security><measurable outcome><mortality><obstacle to care><obstacle to health care><outcome measurement><patient navigation><patient navigator><pediatric><peer support><personalized health intervention><personalized intervention><post intervention><precision interventions><psychiatric co-morbidity><psychiatric comorbidity><psychosocial><racial><racial background><racial origin><randomisation><randomization><randomized trial><randomly assigned><recruit><referral services><resolutions><routine practice><screening><screenings><social><social factors><social health determinants><social support network><socio-economic disparity><socio-economic inequality><socio-economic inequity><socioeconomic disparity><socioeconomic inequality><socioeconomic inequity><success><theories><tool><treatment as usual><type I diabetes><type one diabetes><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><unstable housing><unstably housed><usual care><young adult><young adult age><young adulthood>

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Xiaoxiao Wan

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 52/100

Likely hiring

Solid budget

Active award

$465,547

FY 2026

Project Title

Autoimmune Diabetes: Macrophage Responses

Grant Number:

5R01AI162591-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/14/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT The development of tissue-specific autoimmunity is a chronic process in which finely programmed autoimmune responses progress and culminate in the target organ. Although the tissue environment is eventually dominated by the invasive responses, regulatory elements that function to oppose suc...

Research Terms

<Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Antigen Presentation Pathway><Antigen Processing and Presentation><Antiinflammatory Effect><Apoptotic><Autoimmune><Autoimmune Diabetes><Autoimmune Mechanism><Autoimmune Process><Autoimmune Responses><Autoimmune Status><Autoimmunity><B9 endocrine pancreas><Beta Cell><Biological><Biology><Body Tissues><Brittle Diabetes Mellitus><Bystander Suppression><Cell Communication><Cell Interaction><Cell-to-Cell Interaction><Chronic><Complex><Development><Disease><Disorder><Elements><Endocrine Pancreas><Environment><Event><Human><Humulin R><IDDM><Immune><Immunes><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Inflammatory Response><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Invaded><Islands of Langerhans><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Macrophage><Mediating><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Murine><Mus><Mφ><Nesidioblasts><Novolin R><Organ><PTK Receptors><Pancreatic Islets><Pars endocrina pancreatis><Pathogenicity><Process><Receptor Protein-Tyrosine Kinases><Receptor Tyrosine Kinase Gene><Regular Insulin><Regulation><Regulatory Element><Regulatory T-Lymphocyte><Role><STZ><Streptozocin><Streptozotocin><Sudden-Onset Diabetes Mellitus><T cell infiltration><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><Therapeutic><Tissues><Transmembrane Receptor Protein Tyrosine Kinase><Treg><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Tyrosine Kinase Linked Receptors><Tyrosine Kinase Receptors><Zanosar><anti-inflammatory effect><autoimmune attack><autoimmune destruction><autoimmune pathogenesis><autoreactive T cell><biologic><developmental><diabetogenic><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunosuppressive activity><immunosuppressive function><immunosuppressive response><insight><insulin dependent diabetes><insulin dependent type 1><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><prevent><preventing><programs><regulatory T-cells><response><restraint><self-reactive T cell><social role><thymus derived lymphocyte><type I diabetes><type one diabetes><β-cell><β-cells><βCell>

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Damien Reynaud

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 52/100

Likely hiring

Solid budget

Active award

$436,663

FY 2026

Project Title

Diabetic Memory in Hematopoietic Stem Cells

Grant Number:

5R01DK133145-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT DESCRIPTION One in six pregnancies is affected by some form of gestational diabetes (GD), a prevalence that is steadily rising in the context of the worldwide epidemics of obesity and early diabetic onset. Early diagnosis and advances in maternal glucose control have greatly mitigated the pe...

Research Terms

<21+ years old><AGE receptor><ASCVD><Adult><Adult Children><Adult Daughters><Adult Human><Adult Offspring><Adult Sons><Adult-Onset Diabetes Mellitus><Adverse effects><Affect><Assay><Atherosclerosis><Atherosclerosis-prone><Atherosclerosis-susceptible><Atherosclerotic Cardiovascular Disease><Automobile Driving><Bioassay><Biological Assay><Biological Markers><Blood Precursor Cell><Cardiovascular Diseases><Cell Communication and Signaling><Cell Compartmentation><Cell Compartmentations><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cell Signaling><DNA Methylation><Data><Development><Diabetes Mellitus><Diabetic mouse><Early Diagnosis><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Event><Exposure to><Generations><Genetic><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Goals><Health><Hematologic Body System><Hematologic Organ System><Hematopoiesis><Hematopoietic><Hematopoietic Body System><Hematopoietic Cellular Control Mechanisms><Hematopoietic Progenitor Cells><Hematopoietic System><Hematopoietic stem cells><Human><Human Pathology><Inflammation><Intracellular Communication and Signaling><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maintenance><Maturity-Onset Diabetes Mellitus><Memory><Metabolic><Metabolic stress><Modeling><Modern Man><Modification><Molecular><Molecular Target><Morbidity><Mothers><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Obesity Epidemic><Pathologic><Pathology><Pathway interactions><Pattern><Perinatal><Peripartum><Phenotype><Population><Predisposition><Pregnancy><Pregnancy Complications><Pregnancy-Induced Diabetes><Prevalence><Prone to atherosclerosis><RAGE receptor><Receptor Protein><Receptor Signaling><Research><Risk><Role><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Sterility><Susceptibility><T2 DM><T2D><T2DM><TLR protein><Testing><Therapeutic Intervention><Toll-Like Receptor Family Gene><Toll-like receptors><Transmission><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Upregulation><Woman><Work><adiposity><adult onset diabetes><adulthood><advanced glycosylation end product receptor><amphoterin receptor><atheromatosis><atheroprone><atherosclerotic disease><atherosclerotic vascular disease><bio-markers><biologic marker><biological signal transduction><biomarker><blood cell formation><blood cell progenitor><blood glucose regulation><blood progenitor><blood stem cell><blood-forming stem cell><cardiovascular disorder><cell sorting><clinical relevance><clinically relevant><complications during pregnancy><corpulence><developmental><diabetes><diabetes mouse model><diabetic><driving><early detection><epigenetically><glucose control><glucose homeostasis><glucose regulation><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic><hemopoietic progenitor><hemopoietic stem cell><improved><in utero hyperglycemia><intervention therapy><ketosis resistant diabetes><long-term memory><maturity onset diabetes><medical complication><methylome><mouse model><murine model><new diagnostics><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation diagnostics><next generation therapeutics><novel><novel diagnostics><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><offspring><pathway><pharmacologic><potential biological marker><potential biomarker><pregnancy diabetes><pregnancy-related complications><prevent><preventing><prophylactic><receptor><receptor for AGE><receptor for advanced glycation end product><receptor for advanced glycation endproducts><receptor of AGE><social role><sterile><susceptibility to atherosclerosis><tool><transmission process><type 2 DM><type II DM><type two diabetes>

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Rachel H Bonami

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

Good lead · 52/100

Likely hiring

Solid budget

Active award

$421,441

FY 2026

Project Title

The Origins of Human Anti-Insulin B Lymphocytes in Type 1 Diabetes

Grant Number:

5R01DK131070-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2021

End Date:

11/30/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY B lymphocytes orchestrate autoimmune beta cell attack in type 1 diabetes (T1D) by presenting autoantigen to T cells which kill beta cells. Circulating insulin autoantibodies (IAAs) are not directly pathogenic but help predict T1D by signaling this dangerous B/T lymphocyte crosstalk. ...

Research Terms

<0-11 years old><Acceleration><Address><Affinity><Antibody-Secreting Cells><Antigen-Presenting Cells><Antigenic Determinants><Antigens><Assay><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Responses><Autoimmune Status><Autoimmunity><Autologous Antigens><Avidity><B-Cell Antigen Receptor><B-Cell Receptor Binding><B-Cell Subsets><B-Cells><B-Lymphocyte Subsets><B-Lymphocytes><B-cell><B-cell receptor repertoire sequencing><B-cell receptor sequencing><B9 endocrine pancreas><BCR clonality><BCR repertoire sequencing><BCR seq><BCR sequencing><BCRseq><Beta Cell><Binding><Binding Determinants><Bioassay><Biological Assay><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Volume><Brittle Diabetes Mellitus><CITE sequencing><CITE-seq><CITEseq><Canaries><Cell Body><Cell Communication and Signaling><Cell Death><Cell Differentiation><Cell Differentiation process><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cell Signaling><Cell secretion><Cells><Cellular Indexing of Transcriptomes and Epitopes by Sequencing><Cellular Secretion><Child><Child Youth><Children (0-21)><Clinical><Clinical Evaluation><Clinical Testing><Clinical Trials><Clonal Evolution><Clonal Expansion><Coal><Code><Coding System><DNA mutation><Dangerousness><Data><Detection><Diabetes Mellitus><Disease><Disease Progression><Disorder><Early identification><Endocrine Pancreas><Epitope Mapping><Epitopes><Event><Experimental Therapies><Future><Genetic Change><Genetic defect><Genetic mutation><Germ Lines><Germinal Center><Germinoblastic Sarcoma><Germinoblastoma><Goals><Heterogeneity><Hu-mABs><Human><Humulin R><Hybridomas><IA-2 protein><ICA512><IDDM><Ig Genes><Immune Globulins><Immune Targeting><Immune Tolerance><Immune response><Immune signaling><Immunoglobulin Genes><Immunoglobulin-Secreting Cells><Immunoglobulins><Immunologic Tolerance><Individual><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention Strategies><Intracellular Communication and Signaling><Investigation><Investigational Therapies><Investigational Treatments><Islands of Langerhans><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Lymphoma><Malignant Lymphoma><Maps><Measures><Memory><Memory B Cell><Memory B-Lymphocyte><Mice><Mice Mammals><Modern Man><Molecular Interaction><Monitor><Murine><Mus><Mutate><Mutation><Nesidioblasts><Novolin R><PTPRN gene product><Pancreatic Islets><Pars endocrina pancreatis><Participant><Pathogenicity><Pathologic><Pathway interactions><Patients><Phenotype><Population><Process><Production><Recombinants><Regular Insulin><Reticulolymphosarcoma><Risk><Role><SEQ-AN><Sampling><Self-Antigens><Sequence Analyses><Sequence Analysis><Serinus><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Sorting><Specificity><Structure of germinal center of lymph node><Sudden-Onset Diabetes Mellitus><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><Techniques><Technology><Testing><Therapeutic><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Visit><accessory cell><analysis pipeline><antigen binding><antigen bound><autoimmune antibody><autoimmune condition><autoimmune disorder><autoimmune reactivity><autoimmunity disease><autoreactive B cell><autoreactive antibody><autoreactivity><bio-markers><biobank><biologic marker><biological signal transduction><biomarker><biorepository><candidate identification><cell sorting><cellular differentiation><cellular indexing of transcriptomes and epitopes by single cell sequencing><clinical test><defined contribution><diabetes><experiment><experimental research><experimental study><experimental therapeutic agents><experimental therapeutics><experiments><genome mutation><glucose tolerance><host response><humAbs><human mAbs><human monoclonal antibodies><human monoclonals><immune modulatory intervention><immune system response><immune system tolerance><immune unresponsiveness><immunogen><immunointervention><immunological intervention><immunological paralysis><immunoresponse><impaired glucose tolerance><inclusion criteria><insulin dependent diabetes><insulin dependent type 1><insulinoma-associated protein 2><islet><islet autoantibody><islet cell antibody><islet cell antigen 512><islet cell antigen-2><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><molecular sequence database><necrocytosis><pathway><peripheral blood><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><prevent><preventing><protein tyrosine phosphatase, receptor-type, N><relapse prediction><research clinical testing><response><screening><screenings><self reactive B cell><self reactive antibody><sequence database><sequencing database><single cell analysis><social role><thymus derived lymphocyte><type I diabetes><type one diabetes><youngster><β-cell><β-cells><βCell>

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DANA T GRAVES

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 52/100

Likely hiring

Solid budget

Active award

$417,125

FY 2026

Project Title

Diabetes-enhanced Experimental Periodontitis

Grant Number:

5R01DE017732-16

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2007

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Abstract: Diabetes increases the risk and frequency of bacterial infection and alters the adaptive immune response. Surprisingly little is known about the impact of diabetes on dendritic cells and how it may increase susceptibility to periodontitis. The lack of understanding until recently has been ...

Research Terms

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Limin Peng

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 52/100

Likely hiring

Solid budget

Active award

$402,562

FY 2026

Project Title

Developing statistical analysis and prediction tools for continuous glucose monitoring (CGM) use in hospitalized patients with diabetes

Grant Number:

5R01DK136023-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/10/2024

End Date:

1/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary Diabetes mellitus is one of the leading causes of death and disability in the United States. With rapidly ris- ing incidences in the last two decades, diabetes has been reported in over 20% of hospitalized adult patients. Glycemic control plays an important role to help reduce hospi...

Research Terms

<21+ years old><Accounting><Address><Admission><Admission activity><Adopted><Adult><Adult Human><Area><Assessment instrument><Assessment tool><BMI><BMI percentile><BMI z-score><Blood capillaries><Body mass index><Caring><Cause of Death><Clinical><Continuous Glucose Monitor><D-Glucose><Data><Data Analyses><Data Analysis><Detection><Dextrose><Diabetes Mellitus><Discharge from Health Care Facility><Evaluation><Event><Formulation><Future><Glucose><Health Care Costs><Health Costs><History><Hospital Admission><Hospital Mortality><Hospital acquired complications><Hospital complications><Hospitalization><Hospitals><Hyperglycemia><Hypoglycemia><In-house Mortalities><Incidence><Individual><Individual Adjustment><Inhospital Mortality><Inpatients><Intervention Studies><Joints><Length><Link><Methods><Modeling><Modernization><Multi-center clinical study><Multi-site clinical study><Multicenter clinical study><Multisite clinical study><Observational Study><Oral><Outcome><Patient Discharge><Patients><Pattern><Play><Procedures><Process><Quetelet index><Recommendation><Recording of previous events><Recurrence><Recurrent><Reporting><Risk><Role><Safety><Scanning><Series><Specific qualifier value><Specified><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Statistical Methods><Techniques><Testing><Time><Time Factors><Time Study><Translating><United States><adulthood><capillary><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><customized therapy><customized treatment><data interpretation><diabetes><diabetes management><diabetes mellitus management><diabetic management><disability><evidence base><flexibility><flexible><glucometer><glucose meter><glucose monitor><glycemic control><histories><hospital related complications><hospital-associated complications><hyperglycemic><hypoglycemic><hypoglycemic episodes><improved><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><inpatient care><inpatient service><insight><interstitial><intervention research><interventional research><interventional study><interventions research><mortality><nosocomial complications><novel><observational research study><observational survey><patient specific therapies><patient specific treatment><point of care><predictive tools><random forest><semiparametric><social role><sound><statistic methods><statistical analysis><statistical learning><stress hyperglycemia><stress-induced hyperglycemia><stress-related hyperglycemia><tailored medical treatment><tailored therapy><tailored treatment><tool><unique treatment><user friendly computer software><user friendly software><wasting>

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XUELIN LOU

MEDICAL COLLEGE OF WISCONSIN, MILWAUKEE, WI

Good lead · 52/100

Likely hiring

Solid budget

Active award

$390,000

FY 2026

Project Title

ArpC3-mediated actin remodeling in insulin granule exocytosis and diabetes

Grant Number:

5R01DK132088-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2023

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Insulin secretion deficiency is a hallmark of diabetes. In this process, the cortical actin of β cells has recently been recognized as a critical player contributing to diabetes pathogenesis. β cells from type-2 diabetes (T2D) patients show significant signaling alteration associated...

Research Terms

<21+ years old><Ablation><Actin Filaments><Actins><Acute><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Animals><Assay><Automobile Driving><Beta Cell><Bioassay><Biological Assay><Blood Plasma><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cellular Function><Cellular Physiology><Cellular Process><Cellular biology><Complex><Cytoplasmic Granules><D-Glucose><Data><Dephosphin><Dextrose><Diabetes Mellitus><Docking><Dynamin><Dysfunction><Exocytosis><F-Actin><Filamentous Actin><Functional disorder><Genes><Genetic><Genetic Models><Genetic study><Glucose><Human><Humulin R><Image><Imaging Procedures><Imaging Technics><Imaging Techniques><Impairment><In Vitro><Insulin><Insulin Cell><Insulin Secreting Cell><Integrins><Integrins Extracellular Matrix><Internet><Intracellular Communication and Signaling><Investigators><Investments><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Mediating><Membrane><Metabolic><Mice><Mice Mammals><Microfilaments><Microscopy><Modern Man><Molecular><Murine><Mus><Myofilaments><NIDDM><Nanostructures><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Patients><Physiopathology><Plasma><Plasma Serum><Play><Polymers><Process><Regular Insulin><Regulation><Reporting><Research><Research Personnel><Researchers><Resolution><Reticuloendothelial System, Serum, Plasma><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Subcellular Process><T2 DM><T2D><T2DM><Testing><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Vesicle><WWW><Work><adult onset diabetes><adulthood><beta Actin><biological signal transduction><blood glucose regulation><cell biology><cell cortex><cell imaging><cellular imaging><clinical relevance><clinically relevant><confocal imaging><diabetes><diabetes pathogenesis><driving><glucose control><glucose homeostasis><glucose regulation><granule><imaging><in vivo><insight><insulin granule><insulin regulation><insulin secretion><islet><ketosis resistant diabetes><live cell image><live cell imaging><live cellular image><live cellular imaging><maturity onset diabetes><membrane structure><mouse model><murine model><nano><nano meter scale><nano meter sized><nano-sized structures><nano-structures><nanometer scale><nanometer sized><nanoscale><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathophysiology><polymer><polymeric><polymerization><preservation><prevent><preventing><recruit><resolutions><social role><superresolution imaging><superresolution microscopy><tool><trafficking><type 2 DM><type II DM><type two diabetes><web><world wide web><β-Actin><β-cell><β-cells><βCell>

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Anne E Bantle

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 52/100

Likely hiring

Solid budget

Active award

$309,212

FY 2026

Project Title

Personalized Nutrition Using Continuous Glucose Monitoring to Improve Outcomes in Type 2 Diabetes Mellitus

Grant Number:

5R01DK139020-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/16/2024

End Date:

11/30/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Medical nutrition therapy can be an accessible, cost effective and powerful tool for treatment of type 2 diabetes mellitus (T2DM), but this potential has not been realized for all patients. A common shortcoming of dietary strategies is failure to provide personalization, despite increasing ...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Agonist><BMI><BMI percentile><BMI z-score><Blinded><Blood Glucose><Blood Sugar><Body mass index><Client satisfaction><Clinical Trials><Continuous Glucose Monitor><Counseling><D-Glucose><Data><Dextrose><Diabetes Mellitus><Diet><Dietary Intervention><Dietitian><Disease><Disorder><Dose><Drugs><Eating><Education><Educational aspects><Enrollment><Exclusion><Failure><Fasting><Feedback><Food><Food Intake><Food Preferences><Future><GLP-1 receptor><GLP-I receptor><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><Humulin R><Hypoglycemia><Individual><Instruction><Insulin><Intervention><Ketosis-Resistant Diabetes Mellitus><Literature><Maturity-Onset Diabetes Mellitus><Measures><Medical Nutrition Therapy><Medication><Mission><Monitor><Multi-center trial><Multicenter Trials><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nutrition><Nutrition Interventions><Nutrition Therapy><Nutritional Interventions><Participant><Patient Satisfaction><Patients><Pattern><Persons><Pharmaceutical Preparations><Questionnaires><Quetelet index><Randomized><Randomized, Controlled Trials><Recommendation><Regular Insulin><Role><Self Efficacy><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Sulfonylurea Compounds><Survey Instrument><Surveys><System><T2 DM><T2D><T2DM><Testing><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><adult onset diabetes><adulthood><compare to control><comparison control><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost effective><design><designing><diabetes><diabetes education><diabetes management><diabetes mellitus management><diabetes self-care><diabetes self-management><diabetic management><diet adherence><diet choice><diet education><diet intervention><diet preference><dietary><dietary adherence><dietary choice><dietary guidelines><dietary preferences><diets><dosage><drug/agent><effectiveness testing><effectiveness trial><enroll><fasted><fasting glucose><fasts><food choice><glucagon-like peptide-1 receptor><glycemic control><group intervention><hemoglobin A1c><hypoglycemic><hypoglycemic episodes><improved><improved outcome><individualized nutrition><ketosis resistant diabetes><life style intervention><lifestyle intervention><maturity onset diabetes><new approaches><novel approaches><novel strategies><novel strategy><nutrition education><nutritional guideline><personalization of treatment><personalized medicine><personalized nutrition><personalized therapy><personalized treatment><randomisation><randomization><randomized control trial><randomly assigned><response><satisfaction><sex><social role><sulfonylurea><tool><type 2 DM><type II DM><type two diabetes><virtual health visit><virtual visit>

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Jeffrey Robert Millman

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 52/100

Likely hiring

Solid budget

Active award

$265,838

FY 2026

Project Title

Uncovering the Interplay Among Pancreatic Tissue Types, Inflammation, and Genotypes in Type 1 Diabetes

Grant Number:

5R01DK138469-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/2/2024

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 1 diabetes (T1D) is a chronic autoimmune disease caused by the destruction of pancreatic beta cells in the islets of Langerhans. Genome-wide associated studies (GWAS) have implicated several dozen genes in T1D, but few are expressed by or unique to beta cells. We hypothesize that a combination ...

Research Terms

<(TNF)-α><Affect><Amylases><Assay><Autoimmune Diseases><Autoimmune Status><Autoimmunity><B9 endocrine pancreas><Beta Cell><Beta Proprotein Interleukin 1><Bioassay><Biological Assay><Body Tissues><Brittle Diabetes Mellitus><CFTR><CFTR Protein><Cachectin><Cell Body><Cells><Chromatin><Co-culture><Cocultivation><Coculture><Coculture Techniques><Coleonol><Communities><Coxsackie B Viruses><Coxsackieviruses B><Cystic Fibrosis Transmembrane Conductance Regulator><Data><Data Set><Development><Diabetes Mellitus><Diastase><Disease><Disorder><Dysfunction><Endocrine><Endocrine Pancreas><Enhancers><Environmental Factor><Environmental Risk Factor><Esteroproteases><Event><Exocrine pancreas><Forskolin><Functional disorder><GWA study><GWAS><Gene Expression><Gene Transcription><Generations><Genes><Genetic><Genetic Transcription><Genotype><Hormone secretion><Human><Humulin R><IDDM><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><IL-1 beta><IL-1 β><IL-1-b><IL-1β><IL1-Beta><IL1-β><IL1B Protein><IL1F2><IL1β><Immune><Immune Interferon><Immune response><Immune system><Immunes><Immunoglobulin Enhancer-Binding Protein><Infection><Inflammation><Inflammatory><Inflammatory Response><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Interferon Gamma><Interferon Type II><Interleukin 1beta><Interleukin-1 beta><Interleukin-1β><Islands of Langerhans><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Lipase><Macrophage><Macrophage-Derived TNF><Methods><Modern Man><Monocyte-Derived TNF><Mφ><NF-kB><NF-kappa B><NF-kappaB><NFKB><Nesidioblasts><Novolin R><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Organoids><Pancreas><Pancreatic><Pancreatic Islets><Pancreatic beta Cell><Pancreatic β-Cell><Pars endocrina pancreatis><Patients><Peptidases><Peptide Hydrolases><Physiopathology><Play><Preinterleukin 1 Beta><Printing><Protease Gene><Proteases><Proteinases><Proteins><Proteolytic Enzymes><Protocol><Protocols documentation><RNA Expression><Regular Insulin><Reproducibility><Research><Research Design><Risk-associated variant><Role><Single cell seq><Stem Cell Research><Stress><Structure of beta Cell of islet><Study Type><Sudden-Onset Diabetes Mellitus><Swelling><System><T-Cell Activation><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Tissues><Transcript><Transcription><Transcription Factor NF-kB><Triacylglycerol Hydrolase><Triacylglycerol Lipase><Triacylglycerol acylhydrolase><Tributyrinase><Triglyceridase><Triglyceride Lipase><Triolean Hydrolase><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Variant><Variation><activate T cells><autoimmune condition><autoimmune disorder><autoimmunity disease><cell type><chronic autoimmune disease><cystic fibrosis transmembrane regulator><cytokine><developmental><diabetes><environmental risk><exocrine pancreatic><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><hormonal secretion><host response><human derived pluripotent stem cell><human pluripotent stem cell><human tissue><iPS><iPSC><iPSCs><immune system response><immunoresponse><improved><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cells derived from patients><induced pluripotent stem cells from patients><inducible pluripotent cell><inducible pluripotent stem cell><insight><insulin dependent diabetes><insulin dependent type 1><islet><juvenile diabetes><juvenile diabetes mellitus><kappa B Enhancer Binding Protein><ketosis prone diabetes><lFN-Gamma><multidisciplinary><novel><nuclear factor kappa beta><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><patient derived human iPS><patient derived human iPSC><patient derived human induced pluripotent stem cell><patient derived iPS><patient derived iPSC><patient derived induced pluripotent cells><patient derived induced pluripotent stem cells><patient-derived pluripotent stem cells><programs><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><single cell next generation sequencing><single cell sequencing><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stem><stem cell study><study design><success><thymus derived lymphocyte><tool><tributyrase><type I diabetes><type one diabetes><whole genome association analysis><whole genome association study><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HUBERT M TSE

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 52/100

Likely hiring

Solid budget

Active award

$265,838

FY 2026

Project Title

Uncovering the Interplay Among Pancreatic Tissue Types, Inflammation, and Genotypes in Type 1 Diabetes

Grant Number:

5R01DK138469-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/2/2024

End Date:

12/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 1 diabetes (T1D) is a chronic autoimmune disease caused by the destruction of pancreatic beta cells in the islets of Langerhans. Genome-wide associated studies (GWAS) have implicated several dozen genes in T1D, but few are expressed by or unique to beta cells. We hypothesize that a combination ...

Research Terms

<(TNF)-α><Affect><Amylases><Assay><Autoimmune Diseases><Autoimmune Status><Autoimmunity><B9 endocrine pancreas><Beta Cell><Beta Proprotein Interleukin 1><Bioassay><Biological Assay><Body Tissues><Brittle Diabetes Mellitus><CFTR><CFTR Protein><Cachectin><Cell Body><Cells><Chromatin><Co-culture><Cocultivation><Coculture><Coculture Techniques><Coleonol><Communities><Coxsackie B Viruses><Coxsackieviruses B><Cystic Fibrosis Transmembrane Conductance Regulator><Data><Data Set><Development><Diabetes Mellitus><Diastase><Disease><Disorder><Dysfunction><Endocrine><Endocrine Pancreas><Enhancers><Environmental Factor><Environmental Risk Factor><Esteroproteases><Event><Exocrine pancreas><Forskolin><Functional disorder><GWA study><GWAS><Gene Expression><Gene Transcription><Generations><Genes><Genetic><Genetic Transcription><Genotype><Hormone secretion><Human><Humulin R><IDDM><IFN-Gamma><IFN-g><IFN-γ><IFNG><IFNγ><IL-1 beta><IL-1 β><IL-1-b><IL-1β><IL1-Beta><IL1-β><IL1B Protein><IL1F2><IL1β><Immune><Immune Interferon><Immune response><Immune system><Immunes><Immunoglobulin Enhancer-Binding Protein><Infection><Inflammation><Inflammatory><Inflammatory Response><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Interferon Gamma><Interferon Type II><Interleukin 1beta><Interleukin-1 beta><Interleukin-1β><Islands of Langerhans><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Lipase><Macrophage><Macrophage-Derived TNF><Methods><Modern Man><Monocyte-Derived TNF><Mφ><NF-kB><NF-kappa B><NF-kappaB><NFKB><Nesidioblasts><Novolin R><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Organoids><Pancreas><Pancreatic><Pancreatic Islets><Pancreatic beta Cell><Pancreatic β-Cell><Pars endocrina pancreatis><Patients><Peptidases><Peptide Hydrolases><Physiopathology><Play><Preinterleukin 1 Beta><Printing><Protease Gene><Proteases><Proteinases><Proteins><Proteolytic Enzymes><Protocol><Protocols documentation><RNA Expression><Regular Insulin><Reproducibility><Research><Research Design><Risk-associated variant><Role><Single cell seq><Stem Cell Research><Stress><Structure of beta Cell of islet><Study Type><Sudden-Onset Diabetes Mellitus><Swelling><System><T-Cell Activation><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Tissues><Transcript><Transcription><Transcription Factor NF-kB><Triacylglycerol Hydrolase><Triacylglycerol Lipase><Triacylglycerol acylhydrolase><Tributyrinase><Triglyceridase><Triglyceride Lipase><Triolean Hydrolase><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Variant><Variation><activate T cells><autoimmune condition><autoimmune disorder><autoimmunity disease><cell type><chronic autoimmune disease><cystic fibrosis transmembrane regulator><cytokine><developmental><diabetes><environmental risk><exocrine pancreatic><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><hormonal secretion><host response><human derived pluripotent stem cell><human pluripotent stem cell><human tissue><iPS><iPSC><iPSCs><immune system response><immunoresponse><improved><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cells derived from patients><induced pluripotent stem cells from patients><inducible pluripotent cell><inducible pluripotent stem cell><insight><insulin dependent diabetes><insulin dependent type 1><islet><juvenile diabetes><juvenile diabetes mellitus><kappa B Enhancer Binding Protein><ketosis prone diabetes><lFN-Gamma><multidisciplinary><novel><nuclear factor kappa beta><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><patient derived human iPS><patient derived human iPSC><patient derived human induced pluripotent stem cell><patient derived iPS><patient derived iPSC><patient derived induced pluripotent cells><patient derived induced pluripotent stem cells><patient-derived pluripotent stem cells><programs><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><single cell next generation sequencing><single cell sequencing><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stem><stem cell study><study design><success><thymus derived lymphocyte><tool><tributyrase><type I diabetes><type one diabetes><whole genome association analysis><whole genome association study><β-cell><β-cells><βCell>

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Kevan C Herold

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 48/100

Large award

Active award

Team-scale grant

$1,181,404

FY 2026

Project Title

Advanced pancreatic-immune organoid models of type 1 diabetes subtypes and therapeutic responses

Grant Number:

5UG3DK142189-02

Activity Code:

UG3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2026

Why this may be worth a closer look

• Large budget suggests more room for personnel or project growth.

Project Abstract

Type 1 diabetes (T1D) is an autoimmune disease with a metabolic outcome. A number of agents can change the course of the disease when given to patients with new onset (Stage 3 T1D) and teplizumab, the anti-CD3 mAb has been approved to delay the clinical diagnosis in patients at risk, prior to the cl...

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KYLE M LOH

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 48/100

Large award

Active award

Team-scale grant

$1,087,589

FY 2026

Project Title

Stem cell-based modeling of type 1 diabetes to accelerate translation of therapies

Grant Number:

5UG3DK142187-02

Activity Code:

UG3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2026

Why this may be worth a closer look

• Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Type 1 diabetes (T1D) is an autoimmune disease with complex underlying genetics and environmental triggers that results in immune-mediated destruction of insulin-producing beta cells. While animal models of spontaneous autoimmune diabetes have provided substantial insights into the pathogen...

Research Terms

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Audrey Parent

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 48/100

Large award

Active award

Team-scale grant

$1,087,589

FY 2026

Project Title

Stem cell-based modeling of type 1 diabetes to accelerate translation of therapies

Grant Number:

5UG3DK142187-02

Activity Code:

UG3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2026

Why this may be worth a closer look

• Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Type 1 diabetes (T1D) is an autoimmune disease with complex underlying genetics and environmental triggers that results in immune-mediated destruction of insulin-producing beta cells. While animal models of spontaneous autoimmune diabetes have provided substantial insights into the pathogen...

Research Terms

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Qizhi Tang

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Good lead · 48/100

Large award

Active award

Team-scale grant

$1,087,589

FY 2026

Project Title

Stem cell-based modeling of type 1 diabetes to accelerate translation of therapies

Grant Number:

5UG3DK142187-02

Activity Code:

UG3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2026

Why this may be worth a closer look

• Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT Type 1 diabetes (T1D) is an autoimmune disease with complex underlying genetics and environmental triggers that results in immune-mediated destruction of insulin-producing beta cells. While animal models of spontaneous autoimmune diabetes have provided substantial insights into the pathogen...

Research Terms

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KC KENT LLOYD

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Good lead · 48/100

Above-average budget

Recent

Active award

Team-scale grant

$764,750

FY 2026

Project Title

The National Center for Metabolic Phenotyping of Mouse Models of Obesity and Diabetes (MPMOD) at UC Davis

Grant Number:

5U2CDK135074-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. Translational research in vivo using genetic, surgical, humanized, and other types of mouse models are needed to decipher the heterogeneity of diabetes, obesity, and ...

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Julio E Ayala

VANDERBILT UNIVERSITY, Nashville, TN

Good lead · 48/100

Above-average budget

Recent

Active award

Team-scale grant

$753,517

FY 2026

Project Title

Vanderbilt Center for Metabolic Phenotyping in Live Models of Obesity and Diabetes

Grant Number:

5U2CDK135073-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. Overall Center The Vanderbilt Center for Metabolic Phenotyping in Live Models of Obesity and Diabetes (VMPMOD) is built on the strong Vanderbilt history of serving as ...

Research Terms

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GERALD I SHULMAN

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 48/100

Above-average budget

Recent

Active award

Team-scale grant

$745,837

FY 2026

Project Title

Yale Center for Metabolic Phenotyping in Live Models of Obesity and Diabetes

Grant Number:

5U2CDK134901-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. The overarching goal of the Yale MMPC-Live is to provide extramural investigators access to the unique metabolic phenotyping services provided by the Yale MMPC-Live an...

Research Terms

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Carol Fuzeti Elias

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 48/100

Above-average budget

Recent

Active award

Team-scale grant

$692,295

FY 2026

Project Title

Metabolic Phenotyping in Live Models of Obesity and Diabetes

Grant Number:

5U2CDK135066-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

Metabolic disorders, including obesity, diabetes and their complications are among the most pressing health issues worldwide accounting for a substantial national burden of morbidity, mortality, and healthcare costs. The University of Michigan Health System (now Michigan Medicine) has strategically ...

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Kabayam M Venkat Narayan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$211,005

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

5R01DK139632-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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Yan Sun

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$211,005

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

5R01DK139632-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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Nikhil Tandon

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$211,005

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

5R01DK139632-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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Puja Chebrolu

WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$197,100

FY 2026

Project Title

Time course and predictors of progression to postpartum prediabetes and type 2 diabetes in HIV: a prospective longitudinal study of low-income Indian women

Grant Number:

5K23DK136388-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY & ABSTRACT Candidate. Dr. Puja Chebrolu is a physician-scientist who has spent the past five years conducting research on HIV and diabetes in India. She has conducted longitudinal research, developed strong scientific collaborations with Indian scientists, trained an Indian research ...

Research Terms

<(TNF)-α><AIDS Virus><AIDS focused research><AIDS related research><AIDS research><AIDS science><AIDS specific research><Acceleration><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Adult-Onset Diabetes Mellitus><Affect><Apoplexy><Asian Females><Asian Women><BMI><BMI percentile><BMI z-score><Beta Cell><Biometrics><Biometry><Biostatistics><Blood Serum><Body Weight decreased><Body mass index><Brain Vascular Accident><Cachectin><Cardiac infarction><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Cellular Stress><Cellular Stress Response><Cellular injury><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical Trials><Collaborations><Conduct Clinical Trials><Country><Cox Proportional Hazards Models><D-Glucose><Data><Death><Development><Development Plans><Dextrose><Diabetes Mellitus><Diabetes prevention><Drug Therapy><Dysfunction><Environment><Epidemiology><Equation><Fasting><Fats><Fatty acid glycerol esters><Free Fatty Acids><Functional disorder><Future><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Goals><Government><HIV><HIV Infections><HIV burden><HIV disease burden><HIV epidemic burden><HIV focused research><HIV global burden><HIV health burden><HIV individuals><HIV infected individuals><HIV infected persons><HIV investigation><HIV people><HIV positive individuals><HIV positive people><HIV related research><HIV research><HIV science><HIV specific research><HIV viral infection><HIV virus infection><HIV-1 infection><Human Immunodeficiency Viruses><Humulin R><India><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Intervention><Intervention Studies><Investigation on HIV><Investigators><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><LAV-HTLV-III><Leadership><Lifestyle Therapy><Literature><Long-term cohort study><Long-term prospective studies><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort study><Low income><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Lymphadenopathy-Associated Virus><Macrophage-Derived TNF><Maturity-Onset Diabetes Mellitus><Measures><Medicine><Mentors><Mentorship><Monocyte-Derived TNF><Myocardial Infarct><Myocardial Infarction><NIDDM><Nephropathy><Non obese><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonesterified Fatty Acids><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonobese><Novolin R><OGTT><Oral Glucose Tolerance Test><Overweight><PLWH><PWH><Pancreatic beta Cell><Pancreatic β-Cell><Pathogenesis><Persons><Pharmacological Treatment><Pharmacotherapy><Physicians><Physiopathology><Population><Post-partum Women><Postpartum Period><Postpartum Women><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predisposition><Pregnancy><Pregnancy-Induced Diabetes><Pregnant Women><Preparation><Prevention><Prevention Guidelines><Production><Publications><Quetelet index><Regular Insulin><Renal Disease><Research><Research Personnel><Researchers><Resistance><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Risk><Scientific Publication><Scientist><Serum><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Stroke><Structure of beta Cell of islet><Subcellular Process><Susceptibility><T2 DM><T2D><T2DM><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFα><Testing><Time><Training><Tumor Necrosis Factor><Tumor Necrosis Factor-alpha><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Virus-HIV><Visceral fat><Weight Loss><Weight Reduction><Woman><Work><World Health Organization><adult onset diabetes><after gestational diabetes><base><bases><body weight loss><brain attack><cardiac infarct><career development><cell damage><cell injury><cell stress><cellular damage><cerebral vascular accident><cerebrovascular accident><cohort><coronary attack><coronary infarct><coronary infarction><damage to cells><design><designing><developmental><diabetes><diabetes risk><drug intervention><drug treatment><efficacy testing><epidemiologic><epidemiological><expectant mother><expectant women><expecting mother><expecting women><fasted><fasts><following gestational diabetes><gestational diabetes history><glucose tolerance><hazard><heart attack><heart infarct><heart infarction><high risk><high risk group><high risk individual><high risk people><high risk population><human immunodeficiency virus burden><human immunodeficiency virus global burden><human immunodeficiency virus infection><human immunodeficiency virus research><indexing><individuals infected with HIV><individuals who are pregnant><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><inflammation marker><inflammatory marker><injury to cells><insulin resistant><insulin tolerance><intervention research><interventional research><interventional study><interventions research><investigate longitudinal><ketosis resistant diabetes><kidney disorder><life style intervention><lifestyle intervention><long-term study><longitudinal investigation><longitudinal outcome studies><longitudinal research><longitudinal research study><longitudinal, prospective study><maturity onset diabetes><medical college><medical schools><obese individuals><obese people><obese person><obese population><obese subjects><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathophysiology><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people who are pregnant><people with HIV><people with human immunodeficiency virus><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><post-partum><post-partum weight><postpartum weight><pre-diabetes><pre-diabetic><prediabetic><pregnancy diabetes><pregnant females><pregnant mothers><pregnant people><pregnant populations><preparations><prevent><preventing><progression risk><renal disorder><research addressing HIV><research in HIV><research into HIV><research on HIV><research on human immunodeficiency virus><research to address HIV><resistant><school of medicine><science on HIV><science to address HIV><skills><stroked><strokes><studies on HIV><study longitudinal><survey longitudinal><those who are pregnant><type 2 DM><type II DM><type two diabetes><women who are pregnant><wt-loss><young woman><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yelba Castellon-Lopez

CEDARS-SINAI MEDICAL CENTER, LOS ANGELES, CA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$191,689

FY 2026

Project Title

Understanding Barriers to Engagement in the Diabetes Prevention Program among Low-Income Latino Patients: Design and Implementation of an Intervention in Community Health Centers

Grant Number:

5K23DK129828-05

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2022

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

ABSTRACT: My long-term career goal is to be an independent investigator in health services research, conducting investigations that improve outcomes for high-risk populations. My short-term (five-year) career goal is to gain quantitative skills in secondary data analysis, strengthen my expertise in ...

Research Terms

<21+ years old><Address><Adopted><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Amputation><Area><Award><Blindness><Blood Pressure><Body Weight Changes><Body Weight decreased><Budgets><California><Cardiovascular Diseases><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Clinic><Clinical><Clinical Trials><Communities><Community Health Centers><Complications of Diabetes Mellitus><Data><Data Analyses><Data Analysis><Data Collection><Death Rate><Development><Diabetes Complications><Diabetes Mellitus><Diabetes prevention><Diabetes-Related Complications><Diabetic Complications><Dimethylbiguanidine><Dimethylguanylguanidine><Disparities><Disparity><Economic Income><Economical Income><Effectiveness><Eligibility><Eligibility Determination><Epidemic><Face><Federally Qualified Health Center><Food><Future><Goals><Grant><Groups at risk><Health><Health Disparities Research><Health Insurance><Health Services Evaluation><Health Services Research><Health disparities related research><Health system><Incidence><Income><Insurance Coverage><Insurance Status><Intervention><Intervention Studies><Investigation><Investigators><K-Awards><K-Series Research Career Programs><Ketosis-Resistant Diabetes Mellitus><Kidney Failure><Kidney Insufficiency><Latino><Learning><Life Style><Lifestyle><Limited English Proficiency><Link><Los Angeles><Low Income Population><Low income><Low income group><Maturity-Onset Diabetes Mellitus><Measures><Medicaid><Medical><Medical Care Research><Mentors><Metformin><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><Natural experiment><Neighborhood Health Center><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Outcome Study><Overweight><Participant><Patient Recruitments><Patients><People at risk><Personalized medical approach><Persons at risk><Physical activity><Pilot Projects><Policies><Population><Populations at Risk><Pragmatic clinical trial><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Process><Protocol Screening><Randomization trial><Randomized, Controlled Trials><Renal Failure><Renal Insufficiency><Reporting><Research><Research Career Program><Research Personnel><Research Resources><Researchers><Resources><Risk><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Subgroup><T2 DM><T2D><T2DM><Techniques><Translating><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><Vulnerable Populations><Weight Change><Weight Loss><Weight Reduction><Work><acceptability and feasibility><adult onset diabetes><adulthood><arm><assess effectiveness><barriers to implementation><beneficiary><body weight loss><cardiovascular disorder><career><career development><community advisory board><community advisory committee><community advisory panel><community barrier><community engaged approach><community engaged approaches><community engaged intervention><community engaged strategies><community engaged strategy><community informed intervention><community intervention><community level intervention><community partnered approach><community partnered strategy><community partners><community-based intervention><community-based partners><community-level barrier><community-partnered intervention><cost><data interpretation><design><designing><determine effectiveness><developmental><diabetes><diabetes prevention program><diabetes risk><disparity in health><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><evidence base><examine effectiveness><experience><faces><facial><health disparities science><health disparity><health insurance plan><health plan><health plans><high risk><high risk group><high risk individual><high risk people><high risk population><implementation barriers><implementation challenges><implementation intervention><improved><improved outcome><incomes><individualized approach><interest><intervention design><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><low income individual><low income people><maturity onset diabetes><minority communities><mortality rate><obese individuals><obese people><obese person><obese population><obese subjects><participant recruitment><patient centered><patient oriented><personalized approach><pilot study><pilot trial><pre-diabetes><pre-diabetic><precision approach><prediabetic><prevent><preventing><primary outcome><programs><randomized control trial><randomized trial><recruit><safety net><secondary outcome><services research><skill acquisition><skill development><skills><social health determinants><success><tailored approach><therapy design><treatment design><type 2 DM><type II DM><type two diabetes><vision loss><visual loss><vulnerable group><vulnerable individual><vulnerable people><wt-loss>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kabayam M Venkat Narayan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$187,876

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yan Sun

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$187,876

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nikhil Tandon

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$187,876

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Charlotte Wang Chen

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$183,558

FY 2026

Project Title

T1D-PATCHY (Type 1 Diabetes-Promoting Access to diabetes Technology with Community Health Workers for Youth)

Grant Number:

1K23DK146191-01

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2026

End Date:

2/28/2031

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Abstract Youth with type 1 diabetes (T1D) from low-income families or on public insurance are more likely to have adverse health outcomes and are less likely to use diabetes devices compared with their peers. Diabetes technology can serve as an intervention target to improve health outcomes for all ...

Research Terms

<18 year old><18 years of age><4 year old><4 years of age><Acute><Address><Administrator><Adoption><Advocate><Appointment><Award><Brittle Diabetes Mellitus><Care Givers><Caregivers><Caring><Childhood><Children's Hospital><Clinic><Clinical><Clinical Trials><Communities><Community Health Aides><Competence><Conduct Clinical Trials><Conflict><Conflict (Psychology)><Consent><Consolidated Framework for Implementation Research><Consolidated Framework for Implementation Science><Consolidated Framework for Implementing Change><Continuous Glucose Monitor><Data><Devices><Diabetes Mellitus><Education><Educational aspects><Employee><Evidence based intervention><Face><Family><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Grant><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Health Care Providers><Health Personnel><Health Services><Health Services Evaluation><Health Services Research><Health system><Hemoglobin A(1)><Human Resources><Humulin R><IDDM><Individual><Insulin><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intervention><Interview><Investigators><Juvenile-Onset Diabetes Mellitus><K12><K12 Award><K12 Mechanism><K12 Program><K23 Award><K23 Mechanism><K23 Program><Ketosis-Prone Diabetes Mellitus><Manpower><Maps><Medicaid><Medical><Medical Care Research><Medical center><Mentored Clinical Scientist Development Program><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Mentorship><Methodology><Modeling><Mollies><NIH><National Institutes of Health><Novolin R><Outcome><Pediatric Hospitals><Pharmacies><Pharmacy facility><Position><Positioning Attribute><Process><Provider><Public Health><QOL><Quality of life><Randomized><Randomized, Controlled Trials><Records><Regular Insulin><Research><Research Personnel><Researchers><School Health Nursing><School Nursing><Schools><Self Efficacy><Specialty><Statistical Methods><Structure><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Training><Trust><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States National Institutes of Health><Youth><Youth 10-21><acute care><age 18><age 18 years><age 4><age 4 years><care coordination><career development><community based participatory research><community health worker><community intervention><community led research><community level intervention><community participatory research><community partnered participatory research><community-based intervention><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><coordinating care><design><designing><diabetes><diabetes distress><diabetes-related distress><diabetes-specific distress><differences in health><distress related to diabetes><distress specific to diabetes><effectiveness and implementation trial><effectiveness/implementation hybrid trial><effectiveness/implementation trial><eighteen year old><eighteen years of age><evidence base><experience><faces><facial><four year old><four years of age><glycemic control><health care personnel><health care worker><health difference><health in school><health provider><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><hemoglobin A1c><human centered design><implementation outcomes><implementation science><implementation strategy><improved><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><intervention mapping><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><lower income families><medical care providers><medical personnel><medical specialties><member><mortality><novel><participatory action research><pediatric><peer><personnel><post intervention><primary outcome><process improvement><programs><psychosocial outcome><psychosocial sequelae><public health insurance><public insurance><randomisation><randomization><randomized control trial><randomly assigned><retention rate><retention strategy><satisfaction><scale up><school health><services research><skills><social><social competition><statistic methods><strategies for implementation><team-based care><treatment provider><type I diabetes><type one diabetes><uptake><youth age>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Laura C. Hawks

MEDICAL COLLEGE OF WISCONSIN, MILWAUKEE, WI

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$178,189

FY 2026

Project Title

MANAGe-DM: novel nurse case management to improve diabetes outcomes in Black men recently released from incarceration

Grant Number:

5K23DK132505-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/1/2022

End Date:

11/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Diabetes is a significant public health problem that affects 34 million individuals in the United States with substantial disparities in prevalence and outcomes by race. A growing body of evidence highlights social risk as factors which account for disparities in diabetes outcomes. Incarceration is ...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Aging><American><Anxiety><Behavior><Black><Black American><Black race><Blood Pressure><Cardiac Diseases><Cardiac Disorders><Care Manager><Caring><Case Management Nurse><Case Manager><Caucasian male><Caucasian men><Cause of Death><Cessation of life><Cholesterol><Chronic Disease><Chronic Illness><Clinic><Clinical><Communities><Complication><Country><Death><Death Rate><Decrease health disparities><Diabetes Mellitus><Diet><Disease Management><Disorder Management><Disparities><Disparity><Economic Income><Economical Income><Exercise><Exposure to><Future><General Population><General Public><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Grant><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Health Care Providers><Health Care Systems><Health Personnel><Health Priorities><Health disparity mitigation><Health disparity reduction><Health system><Heart Diseases><Hemoglobin A(1)><High Prevalence><Hypertension><Imprisonment><Income><Individual><Intervention><Intervention Studies><Ketosis-Resistant Diabetes Mellitus><Knowledge><LDL Cholesterol><LDL Cholesterol Lipoproteins><Low Density Lipoprotein Cholesterol><Lower health disparities><Maturity-Onset Diabetes Mellitus><Mediator><Mental Depression><Mitigate health disparities><Modeling><Morbidity><Motivation><NIDDM><Navigation System><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nurses><Outcome><Participant><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Population><Prevalence><Prevention><Prisons><Public Health><QOL><Quality of life><Race><Races><Randomized><Randomized, Controlled Trials><Reduce health disparities><Research><Risk><Risk Factors><Role><Self Care><Self Efficacy><Slow-Onset Diabetes Mellitus><Social support><Stable Diabetes Mellitus><Stress><System><T2 DM><T2D><T2DM><Testing><Training><Treatment Efficacy><Trust><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Unemployment><United States><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vulnerable Populations><Wisconsin><Work><adult onset diabetes><adulthood><beta-Lipoprotein Cholesterol><black male><black man><black men><care as usual><career development><caucasian American><chronic disorder><community engaged participatory research><community engaged research><community partnered research><community-engaged study><community-partnered study><comparing females and males><comparing women and men><death risk><depression><diabetes><diabetes control><diabetes education><diabetes mellitus control><diets><disease control><disorder control><drug adherence><drug compliance><effective intervention><empowerment><experience><females compared to males><females compared with males><females versus males><females vs. males><flexibility><flexible><food insecure><food insecurity><food scarcity><glycemic control><health and care delivery><health care delivery><health care personnel><health care worker><health delivery systems><health provider><health services delivery><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><heart disorder><hemoglobin A1c><high blood pressure><housing insecurity><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><incarcerated><incarceration><incomes><innovate><innovation><innovative><insecure housing><intervention arm><intervention effect><intervention efficacy><intervention research><interventional research><interventional study><interventions research><jobless><joblessness><ketosis resistant diabetes><low food security><male><maturity onset diabetes><medical care providers><medical personnel><medication adherence><medication compliance><mortality><mortality rate><mortality risk><novel><nurse><nursing standards><out of work><patient oriented outcomes><peer><personal care><population health><prison population><racial><racial background><racial origin><randomisation><randomization><randomized control trial><randomly assigned><skills><skills training><social><social influence><social role><social support network><therapeutic efficacy><therapy efficacy><treatment arm><treatment as usual><treatment provider><type 2 DM><type II DM><type two diabetes><unemployed><usual care><vulnerable group><vulnerable individual><vulnerable people><white American><white male><white men><women compared to men><women compared with men><women versus men><women vs. men><♂>

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Kelsey Nicole Serier

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$165,691

FY 2026

Project Title

Longitudinal Associations of Posttraumatic Stress Disorder with Incident Type 2 Diabetes and Poor Glycemic Control in a Large National Cohort

Grant Number:

5K08DK138296-03

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2024

End Date:

1/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary This K08 Mentored Clinical Scientist Development Award will provide Dr. Kelsey Serier with training to develop an independent research career devoted to understanding the effect of trauma and trauma-related negative mental health sequalae, namely posttraumatic stress disorder (PTSD),...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Attention><Autonomic Dysfunction><Award><Behavioral Sciences><Biological><Black><Black race><Chronic><Cox Proportional Hazards Models><Data><Data Analyses><Data Analysis><Data Sources><Development><Diabetes Mellitus><Diabetes prevention><Diagnosis><Diagnostic><Electronic Health Record><Endocrinology><Environmental Factor><Environmental Risk Factor><Epidemiologic Methodology><Epidemiologic Methods><Epidemiologic research methodology><Epidemiologic research methods><Epidemiological Methods><Epidemiological Techniques><Epidemiology><Ethnic Origin><Ethnicity><Exposure to><Female Health><Foundations><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Grant><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Costs><Health Costs><Health Informatics><Hemoglobin A(1)><Hispanic><Homelessness><Incidence><Individual><Intervention><Investigation><Investigators><Ketosis-Resistant Diabetes Mellitus><Knowledge><Laboratories><Latino><Link><Literature><Logistic Regressions><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Maturity-Onset Diabetes Mellitus><Measures><Medical><Mental Depression><Mental Health><Mental Hygiene><Mental disorders><Mental health disorders><Mentored Clinical Scientist Development Award (K08)><Mentored Clinical Scientists Development Award><Mentorship><Metabolism and Endocrinology><Methodology><Methods Epidemiology><Methods in epidemiology><Modeling><Modification><Morbidity><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Outcome><PTSD><Pathway interactions><Patient Self-Report><Phased Career Development><Post-Traumatic Neuroses><Post-Traumatic Stress Disorders><Posttraumatic Neuroses><Prevalence><Prevention><Psychiatric Disease><Psychiatric Disorder><Psychological Health><Psychosocial Factor><Public Health><Public Health Informatics><Race><Races><Research><Research Personnel><Researchers><Risk><Risk Factors><Role><Sampling><Science><Self-Report><Series><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Subgroup><Survey Instrument><Surveys><T2 DM><T2D><T2DM><Testing><Time><Training><Trauma><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Variant><Variation><Veterans><Veterans Health Administration><Veterans Health Affairs><Woman><Women's Health><Work><Writing><active followup><adult onset diabetes><adulthood><biologic><burden of disease><burden of illness><career><co-morbid><co-morbid depression><co-morbid with depression><co-morbidity><co-morbidity with depression><cohort><comorbid depression><comorbid with depression><comorbidity><comorbidity with depression><comparator group><comparison group><consumer informatics><cost><data interpretation><depression><depression co-morbidity><depression comorbidity><design><designing><developmental><diabetes><diabetes risk><diabetes self-care><diabetes self-management><disease burden><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><environmental risk><epidemiologic><epidemiological><ethnic identity><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><exposure to trauma><follow up><follow-up><followed up><followup><food insecure><food insecurity><food scarcity><glycemic control><group of color><hemoglobin A1c><homeless><houselessness><individual of color><ketosis resistant diabetes><long-term study><longitudinal outcome studies><longitudinal research study><low food security><malleable risk><maturity onset diabetes><mental illness><minority health><modifiable risk><mortality><novel><pathway><people of color><person of color><physical conditioning><physical health><poor sleep><population of color><post-trauma stress disorder><posttrauma stress disorder><programs><prospective><psychiatric co-morbidity><psychiatric comorbidity><psychiatric illness><psychologic><psychological><psychological disorder><psychosocial variables><racial><racial background><racial diversity><racial identity><racial minority group><racial minority individual><racial minority people><racial minority population><racial origin><racially diverse><sex><skills><social factors><social role><trauma exposure><traumatic neurosis><traumatic stress><type 2 DM><type II DM><type two diabetes><unhoused>

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Melissa DeJonckheere

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$156,358

FY 2026

Project Title

Optimizing Use of Advanced Diabetes Technology for Self-Management in Adolescents with Type 1 Diabetes: Integration of Real-Time Glucose and Narrative Data

Grant Number:

5K01DK134766-04

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY / ABSTRACT Type 1 diabetes (T1D) is one of the most common pediatric chronic conditions, affecting 187,000 children and adolescents in the United States. It is a complex and demanding condition that requires intensive self- management regimens to prevent complications. Despite improv...

Research Terms

<0-11 years old><12-20 years old><18 year old><18 years of age><19 year old><19 years of age><Acute><Adherence><Adolescence><Adolescent><Adolescent Development><Adolescent Health Services><Adolescent Youth><Affect><Award><Behavior><Behavioral><Biological Function><Biological Process><Blood Glucose Self-Monitoring><Blood Sugar Self-Monitoring><Brittle Diabetes Mellitus><Cardiovascular Diseases><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Child><Child Youth><Childhood><Children (0-21)><Chronic><Clinical Trials><Collection><Communities><Complex><Continuous Glucose Monitor><D-Glucose><Data><Data Collection><Dedications><Development><Development Plans><Devices><Dextrose><Diabetes Mellitus><Diabetic Acidosis><Diabetic Ketoacidosis><Diabetic Ketosis><Ecological momentary assessment><Emotional well being><Environment><Environmental Factor><Environmental Risk Factor><Evaluation><Family Practice><Feedback><Feels well><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Hemoglobin A(1)><Home Blood Glucose Monitoring><Hormonal Change><Humulin R><Hypoglycemia><IDDM><Immediate Memory><Incidence><Individual><Institution><Insulin><Insulin Infusion Systems><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Intervention><Intervention Trial><Interventional trial><Investigators><Juvenile-Onset Diabetes Mellitus><K-Awards><K-Series Research Career Programs><K01 Award><K01 Mechanism><K01 Program><Ketosis-Prone Diabetes Mellitus><Kidney Diseases><Knowledge><Knowledge acquisition><Learning><Life><Life Expectancy><Mentored Research Scientist Development Award><Mentored Training Award><Mentors><Mentorship><Methods><Michigan><Morbidity><Natural Language Processing><Nephropathy><Neuropathy><Normal mental condition><Normal mental state><Normal psyche><Novolin R><Outcome><Patients><Pilot Projects><Problem Solving><Process><Psychological Well Being><Psychosocial Factor><Pump><QOL><Quality of life><Recommendation><Regimen><Regular Insulin><Regulation><Renal Disease><Research><Research Career Program><Research Personnel><Research Scientist Development Award><Researchers><Retinal Diseases><Retinal Disorder><Risk><Self Management><Sense of well-being><Short-Term Memory><Structure><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Techniques><Technology><Testing><Theory of Change><Time><Training><Translating><Treatment Protocols><Treatment Regimen><Treatment Schedule><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States><Universities><Well in self><acceptability and feasibility><adolescence (12-20)><adolescent health><adolescent health outcomes><age 18><age 18 years><age 19><age 19 years><age group><analyzing longitudinal><applied learning><arm><behavior change><cardiovascular disorder><career><career development><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><critical period><data integration><data streams><design><designing><developmental><diabetes><diabetes distress><diabetes-related distress><diabetes-specific distress><diabetic ketoacidotic><distress related to diabetes><distress specific to diabetes><ecological momentary intervention><education research><efficacy outcomes><eighteen year old><eighteen years of age><emotional wellbeing><emotional wellness><environmental risk><executive control><executive function><experience><family medicine><feasibility testing><glycemic control><hands-on learning><hemoglobin A1c><high risk group><high risk individual><high risk people><high risk population><hypoglycemic><hypoglycemic episodes><implementation strategy><improved><insight><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><insulin resistant><insulin tolerance><interactive engagement><interactive learning><intervention mapping><juvenile><juvenile diabetes><juvenile diabetes mellitus><juvenile human><ketosis prone diabetes><kidney disorder><kids><longitudinal analysis><macrovascular complication><macrovascular disease><medical college><medical schools><mental well-being><mental wellbeing><mental wellness><mobile app><mobile application><mobile device application><mortality><natural language understanding><neuropathic><nineteen year old><nineteen years old><pediatric><pilot study><pilot test><prevent><preventing><primary outcome><psychological wellbeing><psychological wellness><psychosocial outcome><psychosocial sequelae><psychosocial variables><psychosocial well-being><psychosocial wellbeing><psychosocial wellness><renal disorder><retina disease><retina disorder><retinopathy><school of medicine><self wellness><sense of wellbeing><skills><strategies for implementation><theories><type I diabetes><type one diabetes><working memory><youngster>

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Brittany Bruggeman

UNIVERSITY OF FLORIDA, GAINESVILLE, FL

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$156,168

FY 2026

Project Title

Natural History and Mechanisms of Exocrine Pancreatic Dysfunction in Pre-Type 1 Diabetes

Grant Number:

5K23DK131363-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2023

End Date:

11/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY. Type 1 diabetes (T1D) is historically described as an endocrine (β-cell) specific autoimmune disease. However, reduced pancreatic size and subclinical exocrine insufficiency are also present at T1D diagnosis. The mechanisms, natural history, and role of these findings in T1D pathoge...

Research Terms

<1st degree relative><7S Gamma Globulin><Affect><Amylases><Atrophic><Atrophy><Autoantibodies><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous><Beta Cell><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Serum><Body Tissues><Brittle Diabetes Mellitus><Cell Body><Cells><Childhood><Clinical><Clinical Evaluation><Clinical Investigator><Clinical Markers><Clinical Research><Clinical Study><Clinical Testing><Collaborations><Data><Deposit><Deposition><Development><Development Plans><Diabetes Mellitus><Diagnosis><Diastase><Digestion><Disease><Disorder><Dysfunction><Early identification><Elastases><Endocrine><Endocrinologist><Enrollment><Environment><Evaluation><Event><Exocrine pancreas><Exocrine pancreatic insufficiency><Feces><First Degree Relative><Florida><Functional disorder><Funding><Gene Expression><Goals><Heterogeneity><Human Subject Research><Humulin R><IDDM><IgG><Immune><Immune infiltrates><Immunes><Immunoglobulin G><Individual><Inflammatory><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention Strategies><Intervention Trial><Interventional trial><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Lead><Learning><Lipase><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Mentors><Mentorship><Mission><NMR Imaging><NMR Tomography><Natural History><Novolin R><Nuclear Magnetic Resonance Imaging><Onset of illness><Organ Donor><Organ Size><Pancreas><Pancreatic><Pancreatic Insufficiency><Pathogenesis><Patients><Pb element><Persons><Phenotype><Physiopathology><Play><Population><Preventative strategy><Prevention strategy><Prevention trial><Preventive strategy><Regular Insulin><Research><Research Design><Research Personnel><Research Proposals><Research Technics><Research Techniques><Researchers><Risk><Risk Marker><Role><Sampling><Scientist><Serum><Slice><Study Type><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Techniques><Tissues><Training><Translational Research><Translational Science><Triacylglycerol Hydrolase><Triacylglycerol Lipase><Triacylglycerol acylhydrolase><Tributyrinase><Triglyceridase><Triglyceride Lipase><Triolean Hydrolase><Trypsinogen><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Universities><Work><Zeugmatography><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive antibody><beta cell autoimmunity><bio-markers><biologic marker><biomarker><biomarker evaluation><birth cohort study><birth cohort survey><career><career development><clinical biomarkers><clinical test><clinically useful biomarkers><cohort><density><design><designing><developmental><diabetes><diabetes pathogenesis><diabetes risk><disease onset><disorder onset><early biomarkers><early detection biomarkers><early detection markers><enroll><exocrine pancreatic><experience><functional loss><heavy metal Pb><heavy metal lead><high risk><immune cell infiltrate><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulin secretion><islet><islet autoantibody><islet autoimmunity><islet cell antibody><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><loss of function><marker evaluation><next generation><novel><pathophysiology><patient centered><patient oriented><pediatric><pre-clinical><preclinical><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><protein expression><research clinical testing><response to therapy><response to treatment><risk predictor><risk predictors><self reactive antibody><skills><social role><stool><study design><success><therapeutic response><therapy response><translation research><translational investigation><treatment response><treatment responsiveness><trial design><tributyrase><type 1 diabetes onset><type I diabetes><type one diabetes><β-cell><β-cells><βCell>

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Jody Ye

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$153,360

FY 2026

Project Title

Investigating the functional roles of CTSH and PGM1 in beta-cells during autoimmune diabetes development

Grant Number:

5K01DK131329-05

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2022

End Date:

1/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary / Abstract This K01 award will allow Dr. Yi (Jody) Ye-Miller to advance her independent research career in the field of type 1 diabetes (T1D). Dr. Ye’s overarching career goal is to understand the pathogenic mechanisms behind the genetic and environmental influence of pancreatic beta...

Research Terms

<0-11 years old><Affect><Aleurain Gene><American><Antigen Presentation><Apoptosis><Apoptosis Pathway><Area><Autoimmune><Autoimmune Diabetes><Autoimmune Responses><Automobile Driving><Beta Cell><Brittle Diabetes Mellitus><CPSB Gene><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><CTSH><CTSH gene><Cas nuclease technology><Cathepsin B3 Gene><Cathepsin BA Gene><Cathepsin H Gene><Cathepsins><Causality><Cell Death><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Cellular Stress><Cellular Stress Response><Child><Child Youth><Children (0-21)><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><DNA Methylation><Data Analyses><Data Analysis><Development><Diabetes Mellitus><Double-Stranded RNA><ER stress><ES cell differentiation><ESC differentiation><Environment><Environmental Factor><Environmental Risk Factor><Enzyme Gene><Enzymes><Equipment><Esteroproteases><Etiology><Funding><GWA study><GWAS><Gene Transcription><Genes><Genetic><Genetic Risk><Genetic Transcription><Genetic predisposing factor><Goals><Grant><Health Care><Human><Humulin R><Hybrids><IDDM><In Vitro><Inbred NOD Mice><Institution><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><K01 Award><K01 Mechanism><K01 Program><Ketosis-Prone Diabetes Mellitus><Knock-out><Knockout><Knowledge><Learning><LoxP-flanked allele><Lysosomes><MGC1519 Gene><Mediating><Medical Education><Medicine><Mentored Research Scientist Development Award><Mentored Training Award><Mentors><Metabolic Glycosylation><Metabolic Protein Degradation><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Murine><Mus><NOD Mouse><Non-Obese Diabetic Mice><Nonobese Diabetic Mouse><Novolin R><Pancreatic beta Cell><Pancreatic β-Cell><Pathogenicity><Pathway interactions><Peptidases><Peptide Hydrolases><Play><Population><Prevalence><Progenitor Cells><Programmed Cell Death><Protease Gene><Proteases><Protein Turnover><Proteinases><Proteolytic Enzymes><RNA Expression><Regular Insulin><Regulatory Protein Degradation><Research><Research Scientist Development Award><Risk-associated variant><Role><Running><Scientist><Stimulus><Structure of beta Cell of islet><Subcellular Process><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><Talents><Technology><Training><Transcription><Transgenic Mice><Translational Research><Translational Science><Translations><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Viral><Viral Diseases><Virus Diseases><Work><autoimmune attack><autoimmune destruction><autoimmune pathogenesis><biological adaptation to stress><career><causation><cell stress><college><collegiate><data interpretation><developmental><diabetes><differentiation in embryonic stem cells><disease causation><driving><dsRNA><early onset><effective therapy><effective treatment><embryonic precursor differentiation><embryonic stem cell differentiation><endoplasmic reticulum stress><enthusiastic atmosphere><enthusiastic environment><environmental risk><experiment><experimental research><experimental study><experiments><floxed><floxed allele><gene product><genetic epidemiologic study><genetic epidemiology><genetic risk factor><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><glycogenesis><glycogenolysis><glycosylation><hESC><human ES cell><human ESC><human embryonic stem cell><immunogenicity><improved><in vitro Model><inherited factor><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><interest><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><mouse model><murine model><necrocytosis><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><overexpress><overexpression><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathway><post-doctoral training><preservation><prevent><preventing><progenitor cell differentiation><progenitor differentiation><protein degradation><reactioncrisis><response><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><social role><stem and progenitor differentiation><stem cell differentiation><stem cells><stress response><stressreaction><supportive atmosphere><supportive environment><translation><translation research><translational investigation><type I diabetes><type one diabetes><viral infection><virus infection><virus-induced disease><whole genome association analysis><whole genome association study><youngster><β-cell><β-cells><βCell>

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ALEXANDRA MONZON

NEMOURS CHILDREN'S HOSPITAL, ORLANDO, ORLANDO, FL

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$150,828

FY 2026

Project Title

Adapting Single Sessions Interventions for Type 1 Diabetes (ASSISTED): Integrated Pediatric Care to Reduce Depression and HbA1c

Grant Number:

5K23DK139431-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Type 1 diabetes (T1D) is a common pediatric chronic medical condition that involves a complex daily regimen. Most children and adolescents with T1D do not meet glycemic control recommendations, suggesting that many likely struggle to manage T1D effectively. Behavioral interv...

Research Terms

<0-11 years old><18 year old><18 years of age><Active Follow-up><Acute><Address><Adolescent><Adolescent Youth><Ambulatory Care><Appointment><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Brittle Diabetes Mellitus><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Child><Child Youth><Childhood><Childhood diabetes><Children (0-21)><Chronic><Chronic Disease><Chronic Illness><Clinic><Clinical Trials><Complex><Complications of Diabetes Mellitus><Conditioning Therapy><Continuous Glucose Monitor><Control Groups><Data><Depression screen><Development Plans><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Emotional Depression><Family><Feedback><Frequencies><Glycated Hemoglobins><Glycohemoglobin A><Glycosylated Hemoglobin><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Costs><Health Care Providers><Health Costs><Health Personnel><Hemoglobin A(1)><IDDM><Individual><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intervention><Intervention Trial><Interventional trial><Interview><Investigators><Juvenile-Onset Diabetes Mellitus><K-Awards><K-Series Research Career Programs><Ketosis-Prone Diabetes Mellitus><Knowledge><Manuals><Medical><Mental Depression><Mental Health><Mental Health Services><Mental Hygiene><Mental Hygiene Services><Mentors><Mission><Modeling><Modernization><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Out-patients><Outpatient Care><Outpatients><Parents><Participant><Process><Provider><Psychological Health><QOL><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Randomization trial><Randomized><Randomized, Controlled Trials><Recommendation><Regimen><Reporting><Research><Research Career Program><Research Design><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Researchers><Risk><Site><Structure><Study Type><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Testing><Training><Treatment Efficacy><Treatment Protocols><Treatment Regimen><Treatment Schedule><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Visit><Youth><Youth 10-21><active followup><age 18><age 18 years><attentional control><barrier to care><barrier to health care><barrier to treatment><behavior intervention><behavioral intervention><career><career development><child health care><chronic disorder><clinical care><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><cost effectiveness><data registry><depression><depression screening><depression symptom><depressive><depressive symptoms><determine efficacy><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes management><diabetes mellitus management><diabetic management><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy testing><eighteen year old><eighteen years of age><evaluate efficacy><evidence base><examine efficacy><experience><flexibility><flexible><follow up><follow-up><followed up><followup><glucometer><glucose meter><glucose monitor><glycemic control><health care personnel><health care worker><health provider><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><hemoglobin A1c><high risk><improved><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><integrated care><integrated health care><integrated model of care><intervention delivery><intervention design><intervention efficacy><juvenile><juvenile diabetes><juvenile diabetes mellitus><juvenile human><ketosis prone diabetes><kids><knowledge integration><medical appointment><medical care providers><medical personnel><mental health care><novel><obstacle to care><obstacle to health care><outpatient treatment><parent><pediatric><pediatric care><pediatric diabetes><pediatric health care><physical conditioning><physical health><pilot test><pilot trial><programs><psychologic><psychological><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><research and methods><skills><social stigma><stigma><study design><systemic barrier><systemic hurdle><systemic obstacle><therapeutic efficacy><therapy design><therapy efficacy><treatment design><treatment provider><treatment strategy><type I diabetes><type one diabetes><youngster><youth age>

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Anna Rachel Kahkoska

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$126,103

FY 2026

Project Title

Building a Real-World Evidence Base for Continuous Glucose Monitoring in Older Adults with Diabetes

Grant Number:

5K01AG084971-03

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Innovative medical technologies can improve health and increase longevity for older adults with chronic disease and multimorbidity, yet new data are needed to promote their adoption and effective use in real-world settings. For example, nearly a quarter of all adults ≥65 yea...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Address><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Aged 65 and Over><Aging><Award><Blood Glucose><Blood Sugar><Brittle Diabetes Mellitus><Calibration><Cardiovascular Diseases><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Caucasian><Caucasian Race><Caucasians><Caucasoid><Caucasoid Race><Characteristics><Chronic Disease><Chronic Illness><Clinical><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Complement><Complement Proteins><Complex><Continuous Glucose Monitor><D-Glucose><Dangerousness><Data><Data Bases><Data Linkages><Data Sources><Databases><Dehydration><Devices><Dextrose><Diabetes Mellitus><Disturbance in cognition><Drops><Economic Models><Economics><Effectiveness><Elderly><Electronic Health Record><Eligibility><Eligibility Determination><Emergent Technologies><Emerging Technologies><Endocrinology><Event><Funding><Future><Geriatrics><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care><Health Care Utilization><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Health system><Hemoglobin A(1)><Hospital Admission><Hospitalization><Humulin R><Hypoglycemia><IDDM><Impaired cognition><Infection><Insulin><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><K-Awards><K-Series Research Career Programs><K01 Award><K01 Mechanism><K01 Program><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Length><Length of Life><Life><Link><Literature><Long-Term Effects><Longevity><Maturity-Onset Diabetes Mellitus><Medical Records><Medical Technology><Medicare><Medicare claim><Mentored Research Scientist Development Award><Mentored Training Award><Mentorship><Metabolism and Endocrinology><Methods><Modeling><Morbidity><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><North Carolina><Notification><Novolin R><Occidental><Older Population><Outcome><Patient Care><Patient Care Delivery><Patient Selection><Patients><Pattern><Pharmaceutical Epidemiology><Pharmacoepidemiology><Policies><Population><Position><Positioning Attribute><Protocol Screening><Provider><QALY><QOL><Quality of life><Quality-Adjusted Life Expectancy><Quality-Adjusted Life Years><Record Linkage Study><Recurrence><Recurrent><Registries><Regular Insulin><Research><Research Career Program><Research Infrastructure><Research Resources><Research Scientist Development Award><Resources><Risk><Safety><Sampling><Slow-Onset Diabetes Mellitus><Specialty><Stable Diabetes Mellitus><Subgroup><Sudden-Onset Diabetes Mellitus><System><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Technology><Testing><Time><Title 18><Training><Translations><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Underrepresented Groups><Underrepresented Populations><Universities><Work><World Health><above age 65><adult onset diabetes><adult youth><adulthood><advanced age><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age group><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><assessing cost effectiveness><body water dehydration><cardiovascular disorder><care for patients><care of patients><career><caring for patients><chronic disorder><clinical effect><cognitive dysfunction><cognitive loss><cohort><complementation><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><cost effectiveness><cost estimate><cost estimation><cost-effectiveness evaluation><cost-effectiveness indices><cost-effectiveness ratio><data base><data collected in real world><determine cost effectiveness><diabetes><diabetes management><diabetes mellitus management><diabetic management><drug epidemiology><economic><economic analysis><economic assessment><economic evaluation><economic impact><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evaluate cost-effectiveness><evidence base><examine cost effectiveness><experience><falls><frailty><geriatric><geriatric medicine><glucometer><glucose meter><glucose monitor><health care service use><health care service utilization><health insurance for disabled><health service use><health service utilization><health services infrastructure><health system infrastructure><healthcare delivery infrastructure><healthcare infrastructure><healthcare system infrastructure><hemoglobin A1c><human old age (65+)><hypoglycemic><hypoglycemic episodes><improved><incremental cost-effectiveness><incrementally cost effective><innovate><innovation><innovative><insight><insulin dependent diabetes><insulin dependent type 1><insurance claims><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><maturity onset diabetes><medical specialties><mortality><multimorbidity><multiple chronic conditions><older adult><older adulthood><older groups><older individuals><older person><over 65 years><pharmacoepidemiologic><pharmacoepidemiological><prevent><preventing><randomized, clinical trials><real world data><real world evidence><routine care><senior citizen><skills><social health determinants><standard of care><technology intervention><technology-based interventions><technology-enabled interventions><technology-focused interventions><training opportunity><translation><type 1 and type 2 diabetes><type 2 DM><type I and type II diabetes><type I diabetes><type II DM><type one diabetes><type two diabetes><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><uptake><white race><young adult><young adult age><young adulthood><≥65 years>

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Kabayam M Venkat Narayan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$115,695

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S3

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Yan Sun

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$115,695

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S3

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Nikhil Tandon

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$115,695

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S3

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RAMA NATARAJAN

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 48/100

Training-friendly

Very recent

Active award

$91,693

FY 2026

Project Title

DIABETES PREVENTION / RISK / OMICS / METABOLISM / THERAPY (PROMT) INTERDISCIPLINARY TRAINING

Grant Number:

5T32DK131943-04

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Within the US, the incidence of diabetes is at epidemic proportions. At the same time, technological advancements are offering promising strategies to therapeutically ameliorate diabetes. The Arthur Riggs Diabetes & Metabolism Research Institute (AR-DMRI) at City of Hope (COH) is uniquely poised as ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Debbie C Thurmond

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA

Good lead · 48/100

Training-friendly

Very recent

Active award

$91,693

FY 2026

Project Title

DIABETES PREVENTION / RISK / OMICS / METABOLISM / THERAPY (PROMT) INTERDISCIPLINARY TRAINING

Grant Number:

5T32DK131943-04

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Within the US, the incidence of diabetes is at epidemic proportions. At the same time, technological advancements are offering promising strategies to therapeutically ameliorate diabetes. The Arthur Riggs Diabetes & Metabolism Research Institute (AR-DMRI) at City of Hope (COH) is uniquely poised as ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Magdalena Sevilla Gonzalez

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 48/100

Training-friendly

Recent

Active award

Career award

$90,000

FY 2026

Project Title

Integration of dietary factors and multi-omic signatures of genetic subtypes to understand diabetes heterogeneity

Grant Number:

5K99DK139461-02

Activity Code:

K99

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2025

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Type 2 diabetes (T2D) is a heterogeneous disease that is the result of the interaction between environmental and genetic factors. T2D heterogeneity has been described with a set of reproducible T2D genetic subtypes representing the contribution of specific pathways such as i...

Research Terms

<Adult-Onset Diabetes Mellitus><Affect><American><Amino Acids><Biological><Black Populations><Black group><Black individual><Black people><Blacks><Ch'i><Complex><Data><Diabetes Mellitus><Diagnosis><Diet><Dietary Factors><Dietary Intervention><Dietary Practices><Disease><Disorder><Doctor of Philosophy><Environment><Environmental Exposure><Environmental Factor><Environmental Risk Factor><Fats><Fatty acid glycerol esters><GI microbiome><Genetic><Genetic Diversity><Genetic Models><Genetic Variation><Genomics><Goals><Heterogeneity><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Individual><Insulin Resistance><Intermediary Metabolism><Intervention><Ketosis-Resistant Diabetes Mellitus><Lipids><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediation><Mentorship><Metabolic><Metabolic Processes><Metabolism><Mission><Modeling><Modification><Molecular><Molecular Fingerprinting><Molecular Profiling><NIDDK><NIDDM><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Negotiating><Negotiation><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Nutrient><Nutrition><Nutrition Interventions><Nutritional Interventions><Outcome><Pathway interactions><Patients><Ph.D.><PhD><Phase><Physiology><Population><Population Genetics><Population Heterogeneity><Position><Positioning Attribute><Precision Health><Process><Public Health><Qi><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Reproducibility><Research><Research Grants><Research Project Grants><Research Projects><Slow-Onset Diabetes Mellitus><Source><Stable Diabetes Mellitus><Strategic Planning><Subgroup><T2 DM><T2D><T2DM><TOPMed><Technology><Testing><Training><Trans-Omics for Precision Medicine><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Variant><Variation><Work><adult onset diabetes><aminoacid><biologic><career><clinical applicability><clinical application><clinical epidemiology><cohort><diabetes><diabetes genetics><diabetes mellitus genetics><diabetes risk><diet intervention><dietary pattern><diets><digestive tract microbiome><diverse populations><enteric microbiome><environmental risk><exposure to environmental agents><exposure to environmental factors><exposure to environmental stimuli><exposure to environmental substances><gastrointestinal microbiome><gene signatures><genetic signature><gut microbiome><gut-associated microbiome><heterogeneous population><human disease><improved><insulin resistant><insulin secretion><insulin tolerance><inter-individual variability><inter-individual variation><intestinal biome><intestinal microbiome><ketosis resistant diabetes><maturity onset diabetes><member><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><microbiome signature><molecular profile><molecular signature><multiomics><multiple omics><panomics><pathway><polygenetic risk scores><polygenic predictors><polygenic risk score><polygenic scores><population diversity><precision medicine><precision nutrition><precision-based medicine><prevent><preventing><programs><randomisation><randomization><randomly assigned><response><therapeutic target><type 2 DM><type II DM><type two diabetes>

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Ashley K Brown

MEDICAL COLLEGE OF WISCONSIN, MILWAUKEE, WI

Good lead · 48/100

Training-friendly

Very recent

Active award

$55,114

FY 2026

Project Title

Mechanisms by which PIM kinase modulates the effector function of autoreactive CD8 T cells in type 1 diabetes

Grant Number:

5F30DK132807-04

Activity Code:

F30

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

4/7/2023

End Date:

4/6/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by T cell destruction of insulin- producing pancreatic b cells. This results in lifelong dependence on exogenous insulin therapy and increases the risk of complications in many organ systems. Advances in understandin...

Research Terms

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Kabayam M Venkat Narayan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$29,039

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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Yan Sun

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$29,039

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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Nikhil Tandon

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 48/100

Likely hiring

Recent

Active award

$29,039

FY 2026

Project Title

Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians

Grant Number:

3R01DK139632-02S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/6/2025

End Date:

12/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Type 2 Diabetes (T2D) and prediabetes are characterized by substantial heterogeneity. Evidence indicates that T2D is comprised of several phenotypic subgroups with diverse clinical characteristics, disease progression, treatment responses, and risks of complications. Nevertheless, significant gaps p...

Research Terms

<21+ years old><Acceleration><Accounting><Active Follow-up><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Asian ancestry><Asian descent><Automobile Driving><Biochemical><Biological><Biological Markers><Biological Specimen Banks><Biological Substance Banks><Blood Plasma><Body Weight><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Characteristics><Clinical><Cohort Studies><Data><Deposit><Deposition><Detection><Development><Diabetes Mellitus><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><European><Evaluation><Evolution><Exhibits><Fats><Fatty acid glycerol esters><Functional disorder><Funding><Gene variant><Genetic><Genomics><Heart Vascular><Hepatic><Heterogeneity><High Prevalence><Image><Impaired fasting glycaemia><India><Individual><Insulin Resistance><Insulin deficiency><Investigation><Ketosis-Resistant Diabetes Mellitus><Knowledge><Maturity-Onset Diabetes Mellitus><Measurement><Metabolic><Modeling><Molecular><Molecular Epidemiology><NHLBI><NIDDM><National Heart, Lung, and Blood Institute><Natural History><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Participant><Pathway interactions><Pattern><Persons><Phenotype><Physiopathology><Plasma><Plasma Serum><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predictive Factor><Prevention><Public Health><Resolution><Reticuloendothelial System, Serum, Plasma><Risk><Risk Factors><Slow-Onset Diabetes Mellitus><South Asian><Stable Diabetes Mellitus><Subgroup><T2 DM><T2D><T2DM><Techniques><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uncertainty><active followup><adult onset diabetes><adulthood><allelic variant><bio-markers><biobank><biologic><biologic marker><biological specimen repository><biomarker><biorepository><biosample repository><biospecimen bank><biospecimen repository><blood glucose regulation><cardiovascular risk><cardiovascular risk factor><circulatory system><clinical relevance><clinically relevant><cohort><cohort research study><cohort survey><computer based prediction><design><designing><developmental><diabetes><diabetes risk><doubt><driving><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><follow up><follow-up><followed up><followup><genetic association><genetic variant><genomic variant><glucose control><glucose homeostasis><glucose regulation><high risk><high risk group><high risk individual><high risk people><high risk population><imaging><impaired fasting glucose><improved><individualized management><individualized patient management><insight><insulin resistant><insulin tolerance><ketosis resistant diabetes><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><mortality><non targeted analysis><nontargeted approach><nontargeted method><nontargeted technique><novel><pathophysiology><pathway><personalized clinical management><personalized disease management><personalized management><polygenetic risk scores><polygenic risk score><population based><pre-diabetes><pre-diabetic><precision management><precision medicine><precision-based medicine><prediabetic><predictive modeling><resolutions><response to therapy><response to treatment><socio-demographics><sociodemographics><specimen bank><specimen repository><therapeutic response><therapy response><translation><translational opportunities><translational potential><translational progress><translational progression><treatment response><treatment responsiveness><type 2 DM><type II DM><type two diabetes><untargeted analysis><untargeted analytical approach><untargeted analytical method><untargeted analytical technique><untargeted approach><untargeted investigations><untargeted method><untargeted strategy><untargeted technique><younger age>

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ROBERT M O'DOHERTY

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 48/100

Training-friendly

Very recent

Active award

$6,000

FY 2026

Project Title

T32 Research Training in Diabetes and Endocrinology

Grant Number:

3T32DK007052-50S2

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/1975

End Date:

6/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

7. PROJECT SUMMARY/ABSTRACT This application is a competitive renewal of the training grant “Research Training in Diabetes and Endocrinology,” which would represent years 47-51 of the first, and longest-running, T32 grant at the University of Pittsburgh. The longevity is a testament to the success o...

Research Terms

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Angelina Dixon

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$193,075

FY 2026

Project Title

SMART-2D: Study of Montelukast's Effects on Renal and Cardiovascular Health in Adolescents and Young Adults with Type 2 Diabetes

Grant Number:

1K23DK146189-01

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2026

End Date:

12/19/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT: CANDIDATE: Angelina Dixon, MD, is currently Chief Medicine/Pediatric Nephrology Fellow, and will join the faculty as an Instructor in July 2025 in the Division of Renal Diseases and Hypertension at the University of Colorado Anschutz Medical Campus (UC-AMC). Dr. Dixon has t...

Research Terms

<12 year old><12 years of age><21+ years old><5-Lipoxygenase><Acute Kidney Failure><Acute Kidney Insufficiency><Acute Renal Failure><Acute Renal Insufficiency><Adolescent and Young Adult><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Agonist><Albuminuria><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Aorta><Arachidonate 5-Lipoxygenase><Arachidonic Acid 5-Lipoxygenase><Asthma><Attenuated><Award><Biological Markers><Biometrics><Biometry><Biopsy><Biopsy Sample><Biopsy Specimen><Biostatistics><Blood><Blood Plasma><Blood Pressure><Blood Reticuloendothelial System><Blood Vessels><Body Tissues><Breast Microcalcification><Brittle Diabetes Mellitus><Bronchial Asthma><CCL2><CCL2 gene><Cachectin Receptors><Cardiovascular Diseases><Caring><Cell Body><Cells><Chemokine, CC Motif, Ligand 2><Childhood><Chronic><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Research><Clinical Study><Clinical Trials><Co-Transporters><Colorado><Complications of Diabetes Mellitus><Cys-LT><D-Glucose><Data><Data Analyses><Data Analysis><Development><Development Plans><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diabetic Kidney Disease><Diabetic Nephropathy><Double-blind trial><Early identification><Elasticity><Endocrinology><Environment><Enzyme Gene><Enzymes><Equipment><Exposure to><Faculty><Frequencies><Funding><Future><GLP-1 receptor><GLP-I receptor><Glomerular Filtration Rate><Glucose><Goals><Grant><Human><Hypertension><Hypertensive Nephropathy><IDDM><Incidence><Infiltration><Inflammation><Inflammation Mediators><Inflammatory><Insulin-Dependent Diabetes Mellitus><Intervention><Investigation><Investigators><Iohexol><Iohexol 350><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Insufficiency><Kidney Urinary System><Knowledge><LTA4 Synthase><Laboratories><Lead><Leadership><Leukotriene A Synthase><Leukotriene A4 Synthase><Leukotriene A4 Synthetase><Leukotrienes><MCAF><MCP-1><MCP1><Macrophage><Maturity-Onset Diabetes Mellitus><Measurement><Measures><Mediating><Medical><Medicine><Mentors><Mentorship><Messenger RNA><Metabolism and Endocrinology><Methods><Mice><Mice Mammals><Microcalcification><Modern Man><Monocyte Chemoattractant Protein-1><Monocyte Chemotactic Protein-1><Monocyte Chemotactic and Activating Factor><Monocyte Chemotactic and Activating Protein><Monocyte Chemotactive and Activating Factor><Monocyte Secretory Protein JE><Morbidity><Murine><Mus><Mφ><NIDDM><NIH><Na element><National Institutes of Health><Nephrology><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Participant><Pathway interactions><Patients><Pb element><Phenotype><Physiologic pulse><Placebos><Plasma><Plasma Serum><Population><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Prevalence><Production><Publications><Pulse><Randomized><Receptor Protein><Renal Disease><Renal Failure><Renal Hypertension><Renal Insufficiency><Renal Plasma Flow><Renal Vascular><Renal function><Renal vessels><Research><Research Associate><Research Methodology><Research Methods><Research Personnel><Research Resources><Research Training><Researchers><Resources><Reticuloendothelial System, Serum, Plasma><Risk><SCYA2><Safety><Scientific Publication><Sham Treatment><Slow-Onset Diabetes Mellitus><Sodium><Stable Diabetes Mellitus><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><TNF Receptor Family Protein><TNF Receptor Superfamily><TNF Receptors><TNFR><Techniques><Time><Tissues><Training><Translational Research><Translational Science><Tumor Necrosis Factor Receptor><Tumor Necrosis Factor Receptor Family><Tumor Necrosis Factor Receptor Superfamily><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States><United States National Institutes of Health><Universities><Urine><Vascular Endothelial Cell><Vascular Endothelium><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vascular resistance><Writing><Youth><Youth 10-21><acute kidney injury><adult onset diabetes><adult youth><adulthood><age 12><age 12 years><arterial stiffening><arterial stiffness><artery stiffening><artery stiffness><attenuate><attenuates><bio-markers><biologic marker><biomarker><brachial artery><cardiovascular disorder><cardiovascular health><career><career development><chronic kidney disease><cost><cysteinyl-leukotriene><cytokine><damage to kidney><data interpretation><design><designing><developmental><diabetes><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><endothelial dysfunction><experience><glucagon-like peptide-1 receptor><heavy metal Pb><heavy metal lead><hemodynamics><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><hypertensive kidney><improved><improved outcome><inflammatory mediator><inhibitor><instructor><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><kidney damage><kidney disorder><kidney function><kidney vascular><kidney vascular structure><lipid mediator><mRNA><maturity onset diabetes><meeting><meetings><montelukast><mortality><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathway><pediatric><post-doc><post-doctoral><post-doctoral trainee><pressure><prevent><preventing><protective effect><randomisation><randomization><randomly assigned><receptor><renal><renal damage><renal disorder><renovascular><research and methods><research associates><sham therapy><skill acquisition><skill development><skills><symporter><translation research><translational investigation><twelve year old><twelve years of age><type 1 diabetes onset><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><urinary><vascular><vascular inflammation><young adult><young adult age><young adulthood><younger age><youth age>

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Michael Samuel Hughes

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$178,410

FY 2026

Project Title

In-hospital use of Automated Insulin Delivery (AID): Current state and future potential

Grant Number:

5K23DK138267-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/9/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Dr. Michael Hughes, an instructor in Stanford University's Division of Endocrinology, Gerontology, and Metabolism, is motivated by his personal experience living with type 1 diabetes to improve care and outcomes for individuals with the condition. He has recognized the pote...

Research Terms

<21+ years old><Acceleration><Acute><Admission><Admission activity><Adoption><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Algorithms><Automation><Blinded><Blood Glucose><Blood Sugar><Brittle Diabetes Mellitus><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Caring><Cessation of life><Classification><Clinical><Clinical Informatics><Collaborations><Consumption><Continuous Glucose Monitor><D-Glucose><Data><Data Set><Death><Development><Devices><Dextrose><Diabetes Mellitus><Effectiveness><Endocrinology><Enrollment><Evolution><FDA approved><Face><Fingers><Future><Gerontology><Glucose><Goals><Grant><Guidelines><Health Care Team><Home><Hospital Admission><Hospital Design><Hospital Personnel><Hospitalization><Hospitals><Hour><Humulin R><Hyperglycemia><Hypoglycemia><IDDM><Iatrogenesis><Individual><Infrastructure><Injection of therapeutic agent><Injections><Inpatients><Insulin><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><Intermediary Metabolism><Interview><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Manuals><Maps><Marketing><Master of Science><Master's Degree><Maturity-Onset Diabetes Mellitus><Medical><Medical Care Team><Medicine><Mentors><Mentorship><Metabolic Processes><Metabolism><Metabolism and Endocrinology><Methods><Morbidity><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Observational Study><Operative Procedures><Operative Surgical Procedures><Out-patients><Outcome><Outpatients><Patient Care><Patient Care Delivery><Patients><Persons><Physicians><Pilot Projects><Position><Positioning Attribute><Preparedness><Process><Publishing><Pump><QOL improvement><Qualifying><Readiness><Recommendation><Regular Insulin><Research><Research Methodology><Research Methods><Research Personnel><Researchers><Risk><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Scientist><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure><Sudden-Onset Diabetes Mellitus><Surgical><Surgical Interventions><Surgical Procedure><System><Systematics><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Techniques><Technology><Testing><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Universities><adult onset diabetes><adulthood><arm><assess effectiveness><care for patients><care of patients><career><caring for patients><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><determine effectiveness><developmental><diabetes><diabetes management><diabetes mellitus management><diabetic management><effectiveness assessment><effectiveness evaluation><enroll><evaluate effectiveness><evidence base><examine effectiveness><experience><faces><facial><gerontologic><glucometer><glucose meter><glucose monitor><glycemic control><high risk><homes><hyperglycemic><hypoglycemic><hypoglycemic episodes><iatrogenic><iatrogenically><iatrogenicity><implementation science><implementation strategy><improved><improved outcome><improvements in QOL><improvements in quality of life><injection therapy><insight><instructor><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><maturity onset diabetes><mortality><observational research study><observational survey><personal protection equipment><personal protective equipment><pilot study><pilot trial><pre-pandemic><programs><prospective><quality of life improvement><research and methods><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><skills><strategies for implementation><surgery><trend><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes>

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Alaina P Vidmar

CHILDREN'S HOSPITAL OF LOS ANGELES, LOS ANGELES, CA

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$168,072

FY 2026

Project Title

Impact of Meal Timing on Glycemic Profiles in Adolescents with Type 2 Diabetes

Grant Number:

5K23DK134801-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2023

End Date:

11/30/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

CANDIDATE: Alaina Vidmar is a pediatric clinical scientist specializing in treatment of adolescents with obesity and type 2 diabetes (T2D). The proposed study will focus on investigating if time-limited eating (TLE: 8-hour eating/16-hour fasting) in adolescents with T2D reduces glycemic excursions, ...

Research Terms

<14 year old><14 years of age><21+ years old><Adherence><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Behavior><Behavioral><Beta Cell><Bioinformatics><Black><Black race><Body Composition><Body Weight><Body Weight decreased><Body fat><Caloric Restriction><Cell Body><Cell Function><Cell Physiology><Cell Process><Cells><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Child Nutrition><Childhood><Clinical><Clinical Trials Design><Communities><Complex><Continuous Glucose Monitor><Country><DEXA><DXA><Data><Deterioration><Development><Diabetes Mellitus><Diagnosis><Dietary Intervention><Dietary intake><Dietary quality><Dimethylbiguanidine><Dimethylguanylguanidine><Disease Progression><Dual-Energy X-Ray Absorptiometry><Dual-Energy Xray Absorptiometry><Dysfunction><Eating><Energy Expenditure><Energy Metabolism><Environment><Fasting><Fats><Fatty acid glycerol esters><Food Intake><Functional disorder><Funding><Glycogen><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><Hepatic><Hepatic Cells><Hepatic Parenchymal Cell><Hepatocyte><Hour><Individual><Institution><Insulin Cell><Insulin Secreting Cell><Intervention><K23 Award><K23 Mechanism><K23 Program><Ketosis-Resistant Diabetes Mellitus><Latino><Life Style><Lifestyle><Lipids><Liver><Liver Cells><MR Imaging><MR Tomography><MRI><MRIs><Macronutrients><Macronutrients Nutrition><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measurement><Measures><Medical><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Metabolic><Metformin><Methods><Monitor><Movement><Multi-center trial><Multicenter Trials><N,N-dimethyl-imidodicarbonimidic diamide><NIDDM><NMR Imaging><NMR Tomography><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nuclear Magnetic Resonance Imaging><Nutrition Interventions><Nutritional><Nutritional Interventions><Obesity><Participant><Peripheral><Personal Satisfaction><Physical activity><Physicians><Physiopathology><Pilot Projects><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Psychologist><Randomized><Recommendation><Regimen><Research><Safety><Scanning><Schedule><Scientist><Severities><Sleep><Slow-Onset Diabetes Mellitus><Specific qualifier value><Specified><Stable Diabetes Mellitus><Statistical Methods><Structure><Subcellular Process><T2 DM><T2D><T2DM><Technology><Testing><Time><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Visceral fat><Weight Loss><Weight Reduction><Youth><Youth 10-21><Zeugmatography><adiposity><adult onset diabetes><adulthood><age 14><age 14 years><assess effectiveness><blood glucose regulation><body movement><body weight loss><calorie restriction><cardiometabolic><cardiometabolism><career development><circadian clock><circadian pacemaker><compare to control><comparison control><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><cost><daily functioning><determine effectiveness><developmental><diabetes><diet intervention><diet quality><dietary><dietary approach><disease phenotype><dosage><eat less><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><examine effectiveness><fasted><fasts><fat metabolism><flexibility><flexible><fourteen year old><fourteen years of age><functional restoration><gender expression><glucometer><glucose RA><glucose control><glucose homeostasis><glucose metabolism><glucose meter><glucose monitor><glucose production><glucose rate of appearance><glucose regulation><glycemic control><hemoglobin A1c><hepatic body system><hepatic organ system><improved><indexing><insight><insulin secretion><insulin sensitivity><interest><intervention effect><juvenile><juvenile human><ketosis resistant diabetes><life style intervention><lifestyle intervention><lipid metabolism><math ability><math achievement><math competence><math competency><math proficiency><mathematic ability><mathematic achievement><mathematic compentence><mathematic compentency><mathematic proficiency><mathematical ability><mathematical achievement><mathematical compentence><mathematical compentency><mathematical proficiency><maturity onset diabetes><minimal risk><number sense><numeracy><nutritional approach><nutritious><oxidation><pathophysiology><pediatric><pediatric nutrition><pilot study><post intervention><pre-diabetes><pre-diabetic><prediabetic><proficient in math><quantitative literacy><randomisation><randomization><randomly assigned><recruit><reduced eating><reduced food intake><response><restore function><restore functionality><restore lost function><secondary outcome><skills><statistic methods><type 2 DM><type II DM><type two diabetes><well-being><wellbeing><wt-loss><youth age><β-cell><β-cells><βCell>

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Margaret Zupa

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$162,530

FY 2026

Project Title

Increasing Reach of Effective Virtual Specialty Care for Adults with Diabetes Through Tailored Modalities

Grant Number:

5K23DK135794-03

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2024

End Date:

6/30/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT ABSTRACT Use of telemedicine to deliver specialty care to adults with type 2 diabetes (T2D) has increased rapidly in the last 3 years and persists as a means to enhance access to care for many patients who face barriers to in- person care, such as those in rural areas, or with limited mobili...

Research Terms

<21+ years old><Access to Care><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><American><Benchmarking><Best Practice Analysis><Blindness><Blood Glucose><Blood Sugar><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Caring><Chronic><Clinical><Clinical Trials Design><Communication><Complex><Complications of Diabetes Mellitus><D-Glucose><Data><Development><Development and Research><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Disease><Disorder><Disparities><Disparity><Drug Prescribing><Drug Prescriptions><Drugs><Education><Educational aspects><Effectiveness><Elements><Endocrine><Endocrinologist><Endocrinology><Evaluation><Face><Frequencies><Future><Geography><Glucose><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health Services><Health Services Accessibility><Health Services Evaluation><Health Services Research><Health system><Hemoglobin A(1)><Home><Humulin R><Immunization><Improve Access><Injections><Insulin><Integrated Health Care Systems><Intervention><Interview><Investigators><K-Awards><K-Series Research Career Programs><K23 Award><K23 Mechanism><K23 Program><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><Knowledge><Link><Maturity-Onset Diabetes Mellitus><Medical Care Research><Medication><Mentored Patient-Oriented Research Career Development Award><Mentored Patient-Oriented Research Career Development Award (K23)><Mentors><Metabolism and Endocrinology><Methods><Modality><Modeling><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Nephropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Outcome><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Patterns of Care><Persons><Pharmaceutical Preparations><Pragmatic clinical trial><Primary Care><Proteins><Protocol><Protocols documentation><Provider><QOC><Quality of Care><R & D><R&D><Randomization trial><Randomized><Regular Insulin><Renal Disease><Reporting><Research><Research Career Program><Research Personnel><Researchers><Retina><Risk><Slow-Onset Diabetes Mellitus><Specialist><Specialty><Stable Diabetes Mellitus><Structure><T2 DM><T2D><T2DM><Telemedicine><Testing><Training><Translating><Transportation><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Urine><Visit><Work><access to health services><access to services><access to treatment><accessibility to health services><adult onset diabetes><adulthood><availability of services><benchmark><care access><care for patients><care of patients><career><career development><caring for patients><co-morbid><co-morbidity><cohort><comorbidity><data sharing><design><designing><developmental><diabetes><diabetes self-care><diabetes self-management><drug/agent><effectiveness and implementation trial><effectiveness-implementation randomized trial><effectiveness/implementation hybrid><effectiveness/implementation hybrid trial><effectiveness/implementation trial><experience><faces><facial><future implementation><health and care delivery><health care delivery><health delivery systems><health service access><health services availability><health services delivery><hemoglobin A1c><high risk><homes><implementation science><improved><improved outcome><integrated health system><integrated system of care><intervention design><ketosis resistant diabetes><kidney disorder><maturity onset diabetes><medical specialties><medication prescription><mortality><multidisciplinary><new approaches><novel approaches><novel strategies><novel strategy><pathway><patient centered><patient oriented><patient oriented outcomes><pilot trial><pragmatic intervention><prescribed medication><randomisation><randomization><randomized trial><randomly assigned><remote monitoring><renal disorder><research and development><rural area><rural location><rural region><satisfaction><service availability><services research><skills><therapy design><treatment access><treatment design><type 2 DM><type II DM><type two diabetes><virtual><virtual care><virtual health care><vision loss><visual loss>

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Michael Fang

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$157,248

FY 2026

Project Title

Disparities in the management and prognosis of type 1 diabetes

Grant Number:

5K01DK138273-03

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/12/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Michael Fang, PhD, MHS is an Assistant Professor in the Department of Epidemiology at Johns Hopkins Bloomberg School of Public Health. He seeks a K01 Mentored Research Scientist Development Award in order to obtain essential skills and mentored research experience for an independent career as a scie...

Research Terms

<0-11 years old><21+ years old><Acute><Adult><Adult Human><Affect><Apoplexy><Area><Brain Vascular Accident><Brittle Diabetes Mellitus><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Child><Child Youth><Childhood diabetes><Children (0-21)><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Collaborations><Complications of Diabetes Mellitus><Coronary Disease><Coronary heart disease><Data><Data Bases><Databases><Decrease health disparities><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Disease Progression><Disparities><Disparity><Doctor of Philosophy><Electronic Health Record><Emergencies><Emergency Situation><Epidemiology><Event><Five-Year Plans><Fostering><Goals><Health><Health Informatics><Health Policy><Health disparity mitigation><Health disparity reduction><Heart Vascular><Heart failure><Hyperglycemia><Hypoglycemia><IDDM><Insulin Infusion Systems><Insulin-Dependent Diabetes Mellitus><International><Investigators><Juvenile-Onset Diabetes Mellitus><K01 Award><K01 Mechanism><K01 Program><Ketosis-Prone Diabetes Mellitus><Life Cycle><Life Cycle Stages><Life Expectancy><Lower health disparities><Measures><Mentored Research Scientist Development Award><Mentored Training Award><Mentors><Mentorship><Metabolic><Methods><Microvascular Dysfunction><Mitigate health disparities><Modeling><Morbidity><Morbidity - disease rate><Neuropathy><Outcome><Patients><Persons><Ph.D.><PhD><Population><Population Research><Population-based research><Population-level research><Predicting Risk><Prognosis><Public Health Informatics><Public Health Schools><Publishing><Recommendation><Reduce health disparities><Research><Research Personnel><Research Proposals><Research Scientist Development Award><Researchers><Retinal Diseases><Retinal Disorder><Risk><Scientist><Stroke><Subgroup><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Technology><Training><Translational Research><Translational Science><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Underserved Population><adulthood><brain attack><cardiac failure><career><career development><cerebral vascular accident><cerebrovascular accident><chronic kidney disease><circulatory system><clinical risk><consumer informatics><coronary disorder><data base><diabetes><diabetes control><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes management><diabetes mellitus control><diabetes mellitus management><diabetic management><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><epidemiologic><epidemiological><experience><forecasting risk><glycemic control><health care policy><hyperglycemic><hypoglycemic><hypoglycemic episodes><insulin dependent diabetes><insulin dependent type 1><insulin infusion device><insulin infusion pump><insulin pump><investigate population><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kids><life course><life-time risk><lifetime risk><metabolic rate><microvascular complications><microvascular disease><model-based simulation><models and simulation><morbidity rate><mortality><neuropathic><pediatric diabetes><population investigation><population level investigation><population specific research><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><professor><programs><retina disease><retina disorder><retinopathy><risk prediction><risk predictions><simulation><skills><social disadvantage><social disparities><social health determinants><social inequality><socio-demographic disparity><socio-demographic inequality><socio-demographic inequity><socio-demographics><socio-economic><socio-economically><sociodemographic disparity><sociodemographic inequality><sociodemographic inequity><sociodemographics><socioeconomically><socioeconomics><stroked><strokes><studies of populations><study of the population><study population><survey population><translation research><translational investigation><trend><type I diabetes><type one diabetes><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><youngster>

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Jennifer Annette Campbell

STATE UNIVERSITY OF NEW YORK AT BUFFALO, AMHERST, NY

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$130,254

FY 2026

Project Title

Conditional Cash Transfer Intervention to Improve Health Outcomes among Inner-City African Americans with T2DM

Grant Number:

5K01DK131319-05

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/12/2022

End Date:

11/30/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Diabetes affects 13% of US adults and African Americans (AAs) have higher prevalence of diabetes, higher diabetes related cost, higher risk of complications, and higher risk of early death compared to non-Hispanic Whites. A key factor that is emerging as a significant contributor to poor health outc...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><African American><African American group><African American individual><African American people><African American population><African Americans><Afro American><Afroamerican><Attention><Behavior><Case Study><Case-Base Studies><Cessation of life><Chronic Disease><Chronic Illness><Chronic stress><Clinical><Cognitive Discrimination><Communities><Cost Effectiveness Analysis><Death><Developing Countries><Developing Nations><Diabetes Mellitus><Diet><Discrimination><Economic Income><Economical Income><Education><Educational aspects><Environment><Exercise><Fostering><Funding><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Instruction><Health Tutoring><Health education><Hemoglobin A(1)><High Prevalence><Impoverished><Imprisonment><Income><Individual><Inequity><Intervention><Ketosis-Resistant Diabetes Mellitus><Less-Developed Countries><Less-Developed Nations><Lived experience><Lived experiences><Maturity-Onset Diabetes Mellitus><Mental Health><Mental Hygiene><Mental disability><Morbidity><NIDDM><Neighborhoods><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Nurses><Outcome><Poverty><Preparation><Preventative care><Preventive care><Productivity><Psychological Health><QOL><QOL improvement><Quality of life><Randomized><Recommendation><Research Resources><Resources><SF-12><Self Care><Slow-Onset Diabetes Mellitus><Social Environment><Societies><Stable Diabetes Mellitus><Stress><Stress and Coping><Structural Racism><System><T2 DM><T2D><T2DM><Testing><Third-World Countries><Third-World Nations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Under-Developed Countries><Under-Developed Nations><United States><Violence><Work><adult onset diabetes><adulthood><alleviating poverty><case report><chronic disorder><compare intervention><comparison intervention><coping><coping with stress><cost><cost efficient analysis><cost estimate><cost estimation><cost-effective analysis><design><designing><developing country><developing nation><diabetes><diabetes education><diets><disability><disparity in health><drug adherence><drug compliance><food insecure><food insecurity><food scarcity><functional status><glycemic control><health disparity><hemoglobin A1c><high risk><housing instability><human capital><improved><improvements in QOL><improvements in quality of life><incarcerated><incarceration><incomes><inner city><instably housed><intergenerational><ketosis resistant diabetes><lack of stable housing><low food security><maturity onset diabetes><medication adherence><medication compliance><mortality><nurse><personal care><physical disability><physically disabled><physically handicapped><poor health outcome><poverty alleviation><preparations><quality of life improvement><racial disparities in health><racial health disparity><randomisation><randomization><randomly assigned><reduced health outcome><residential segregation><skills training><social climate><social context><socioenvironment><socioenvironmental><stress-related coping><type 2 DM><type II DM><type two diabetes><unstable housing><unstably housed><urban area><urban location><urban region><violent><violent behavior><virtual><worse health outcome>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Laura Shaw

NATIONAL JEWISH HEALTH, DENVER, CO

Exploratory lead · 42/100

Training-friendly

Active award

Career award

$114,626

FY 2026

Project Title

Transcriptional control of T cell function during type 1 diabetes

Grant Number:

5K01DK134835-03

Activity Code:

K01

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2028

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY T cells responding to persistent antigen during cancer and chronic infection develop a hyporesponsive phenotype, while T cells responding to self-antigen during type 1 diabetes (T1D) maintain function and eliminate pancreatic beta cells. My co-mentor previously identified a transcrip...

Research Terms

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Andrew Stephen Bomback

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Exploratory lead · 42/100

Likely hiring

Active award

$19,008

FY 2026

Project Title

The Impact of Diabetes on Patients with Glomerular Disease: CureGN-Diabetes

Grant Number:

3R01DK126959-05S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/11/2021

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Primary glomerular diseases often occur in patients with prexisting diabetes mellitus, a common and systemic illness which increases the risk for infection, cardiovascular and progressive chronic kidney disease. The diagnosis, pathology, treatment, complications and outcomes of primary glom...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Ancillary Study><Area><Berger's Disease><Biological Markers><Biopsy><Body Tissues><Calcineurin antagonist><Calcineurin inhibitor><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Collection><Complex><Data><Data Collection><Diabetes Mellitus><Diabetic Glomerulosclerosis><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disorder><Enrollment><Epidemiology><Exclusion><Extramembranous Glomerulopathy><FSGS><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foot Process><Funding><Future><Glomerular disease><Health Care><Heart Vascular><Histologic><Histologically><Histopathology><Hospital Admission><Hospitalization><IGA Glomerulonephritis><IGA Nephropathy><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Modulation Therapy><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infection><Infrastructure><Intracapillary Glomerulosclerosis><Investigators><Kidney><Kidney Urinary System><Kimmelstiel-Wilson Disease><Kimmelstiel-Wilson Syndrome><Knowledge><Lesion><Lesion by Morphology><Letters><Literature><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal observational study><Mediating><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Minority><Morbidity><Morphology><Movement><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Nodular glomerulosclerosis><Outcome><Parents><Pathologic><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pedicel><Persons><Population><Precision care><Productivity><Protocol><Protocols documentation><QOL><Quality of life><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sclerosis><Severities><Site><Specificity><Standardization><Steroid Compound><Steroids><Time><Tissues><United States National Institutes of Health><Variant><Variation><Work><active followup><adulthood><bio-markers><biobank><biologic marker><biomarker><biorepository><body movement><cardiovascular disorder><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical research site><clinical site><co-morbid><co-morbidity><cohort><comorbidity><cost><data harmonization><diabetes><diabetic><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease diagnosis><disease heterogeneity><enroll><epidemiologic><epidemiological><focal glomerulonephritis><follow up><follow-up><followed up><followup><harmonized data><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><individual patient><individualized care><individualized patient care><infection risk><kidney biopsy><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><multi-ethnic><multiethnic><parent><pathway><patient oriented outcomes><personalized care><personalized patient care><precision medicine><precision-based medicine><predict clinical outcome><primary outcome><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><recruit><renal><renal biopsy><segmental glomerulonephritis><therapeutic immunomodulation><therapeutic immunoregulation><tool><treatment risk>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gaia Muallem Coppock

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Exploratory lead · 42/100

Likely hiring

Active award

$19,008

FY 2026

Project Title

The Impact of Diabetes on Patients with Glomerular Disease: CureGN-Diabetes

Grant Number:

3R01DK126959-05S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/11/2021

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Primary glomerular diseases often occur in patients with prexisting diabetes mellitus, a common and systemic illness which increases the risk for infection, cardiovascular and progressive chronic kidney disease. The diagnosis, pathology, treatment, complications and outcomes of primary glom...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Ancillary Study><Area><Berger's Disease><Biological Markers><Biopsy><Body Tissues><Calcineurin antagonist><Calcineurin inhibitor><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Collection><Complex><Data><Data Collection><Diabetes Mellitus><Diabetic Glomerulosclerosis><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disorder><Enrollment><Epidemiology><Exclusion><Extramembranous Glomerulopathy><FSGS><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foot Process><Funding><Future><Glomerular disease><Health Care><Heart Vascular><Histologic><Histologically><Histopathology><Hospital Admission><Hospitalization><IGA Glomerulonephritis><IGA Nephropathy><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Modulation Therapy><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infection><Infrastructure><Intracapillary Glomerulosclerosis><Investigators><Kidney><Kidney Urinary System><Kimmelstiel-Wilson Disease><Kimmelstiel-Wilson Syndrome><Knowledge><Lesion><Lesion by Morphology><Letters><Literature><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal observational study><Mediating><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Minority><Morbidity><Morphology><Movement><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Nodular glomerulosclerosis><Outcome><Parents><Pathologic><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pedicel><Persons><Population><Precision care><Productivity><Protocol><Protocols documentation><QOL><Quality of life><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sclerosis><Severities><Site><Specificity><Standardization><Steroid Compound><Steroids><Time><Tissues><United States National Institutes of Health><Variant><Variation><Work><active followup><adulthood><bio-markers><biobank><biologic marker><biomarker><biorepository><body movement><cardiovascular disorder><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical research site><clinical site><co-morbid><co-morbidity><cohort><comorbidity><cost><data harmonization><diabetes><diabetic><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease diagnosis><disease heterogeneity><enroll><epidemiologic><epidemiological><focal glomerulonephritis><follow up><follow-up><followed up><followup><harmonized data><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><individual patient><individualized care><individualized patient care><infection risk><kidney biopsy><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><multi-ethnic><multiethnic><parent><pathway><patient oriented outcomes><personalized care><personalized patient care><precision medicine><precision-based medicine><predict clinical outcome><primary outcome><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><recruit><renal><renal biopsy><segmental glomerulonephritis><therapeutic immunomodulation><therapeutic immunoregulation><tool><treatment risk>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amy Mottl

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Exploratory lead · 42/100

Likely hiring

Active award

$19,008

FY 2026

Project Title

The Impact of Diabetes on Patients with Glomerular Disease: CureGN-Diabetes

Grant Number:

3R01DK126959-05S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/11/2021

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Primary glomerular diseases often occur in patients with prexisting diabetes mellitus, a common and systemic illness which increases the risk for infection, cardiovascular and progressive chronic kidney disease. The diagnosis, pathology, treatment, complications and outcomes of primary glom...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Ancillary Study><Area><Berger's Disease><Biological Markers><Biopsy><Body Tissues><Calcineurin antagonist><Calcineurin inhibitor><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Collection><Complex><Data><Data Collection><Diabetes Mellitus><Diabetic Glomerulosclerosis><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disorder><Enrollment><Epidemiology><Exclusion><Extramembranous Glomerulopathy><FSGS><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foot Process><Funding><Future><Glomerular disease><Health Care><Heart Vascular><Histologic><Histologically><Histopathology><Hospital Admission><Hospitalization><IGA Glomerulonephritis><IGA Nephropathy><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Modulation Therapy><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infection><Infrastructure><Intracapillary Glomerulosclerosis><Investigators><Kidney><Kidney Urinary System><Kimmelstiel-Wilson Disease><Kimmelstiel-Wilson Syndrome><Knowledge><Lesion><Lesion by Morphology><Letters><Literature><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal observational study><Mediating><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Minority><Morbidity><Morphology><Movement><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Nodular glomerulosclerosis><Outcome><Parents><Pathologic><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pedicel><Persons><Population><Precision care><Productivity><Protocol><Protocols documentation><QOL><Quality of life><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sclerosis><Severities><Site><Specificity><Standardization><Steroid Compound><Steroids><Time><Tissues><United States National Institutes of Health><Variant><Variation><Work><active followup><adulthood><bio-markers><biobank><biologic marker><biomarker><biorepository><body movement><cardiovascular disorder><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical research site><clinical site><co-morbid><co-morbidity><cohort><comorbidity><cost><data harmonization><diabetes><diabetic><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease diagnosis><disease heterogeneity><enroll><epidemiologic><epidemiological><focal glomerulonephritis><follow up><follow-up><followed up><followup><harmonized data><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><individual patient><individualized care><individualized patient care><infection risk><kidney biopsy><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><multi-ethnic><multiethnic><parent><pathway><patient oriented outcomes><personalized care><personalized patient care><precision medicine><precision-based medicine><predict clinical outcome><primary outcome><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><recruit><renal><renal biopsy><segmental glomerulonephritis><therapeutic immunomodulation><therapeutic immunoregulation><tool><treatment risk>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Cynthia C. Nast

UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC

Exploratory lead · 42/100

Likely hiring

Active award

$19,008

FY 2026

Project Title

The Impact of Diabetes on Patients with Glomerular Disease: CureGN-Diabetes

Grant Number:

3R01DK126959-05S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/11/2021

End Date:

1/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Primary glomerular diseases often occur in patients with prexisting diabetes mellitus, a common and systemic illness which increases the risk for infection, cardiovascular and progressive chronic kidney disease. The diagnosis, pathology, treatment, complications and outcomes of primary glom...

Research Terms

<21+ years old><Active Follow-up><Address><Adult><Adult Human><Affect><Ancillary Study><Area><Berger's Disease><Biological Markers><Biopsy><Body Tissues><Calcineurin antagonist><Calcineurin inhibitor><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Data><Collection><Complex><Data><Data Collection><Diabetes Mellitus><Diabetic Glomerulosclerosis><Diabetic Kidney Disease><Diabetic Nephropathy><Diagnosis><Disease><Disorder><Enrollment><Epidemiology><Exclusion><Extramembranous Glomerulopathy><FSGS><Focal and Segmental Glomerulosclerosis><Focal segmental glomerular sclerosis><Foot Process><Funding><Future><Glomerular disease><Health Care><Heart Vascular><Histologic><Histologically><Histopathology><Hospital Admission><Hospitalization><IGA Glomerulonephritis><IGA Nephropathy><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune Modulation Therapy><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infection><Infrastructure><Intracapillary Glomerulosclerosis><Investigators><Kidney><Kidney Urinary System><Kimmelstiel-Wilson Disease><Kimmelstiel-Wilson Syndrome><Knowledge><Lesion><Lesion by Morphology><Letters><Literature><Long-term cohort><Longitudinal Studies><Longitudinal Surveys><Longitudinal cohort><Longitudinal observational study><Mediating><Membranous Glomerulonephritis><Membranous Glomerulonephropathy><Membranous Glomerulopathy><Membranous Nephropathy><Minority><Morbidity><Morphology><Movement><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Natural History><Nodular glomerulosclerosis><Outcome><Parents><Pathologic><Pathology><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Pedicel><Persons><Population><Precision care><Productivity><Protocol><Protocols documentation><QOL><Quality of life><Renal Glomerular Diseases and Syndromes><Renal glomerular disease><Renal glomerular disease or syndrome><Renal glomerular disorder><Renal glomerular syndrome><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Sclerosis><Severities><Site><Specificity><Standardization><Steroid Compound><Steroids><Time><Tissues><United States National Institutes of Health><Variant><Variation><Work><active followup><adulthood><bio-markers><biobank><biologic marker><biomarker><biorepository><body movement><cardiovascular disorder><care for patients><care of patients><caring for patients><chronic kidney disease><circulatory system><clinical research site><clinical site><co-morbid><co-morbidity><cohort><comorbidity><cost><data harmonization><diabetes><diabetic><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disease diagnosis><disease heterogeneity><enroll><epidemiologic><epidemiological><focal glomerulonephritis><follow up><follow-up><followed up><followup><harmonized data><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><individual patient><individualized care><individualized patient care><infection risk><kidney biopsy><long term observational study><long-term study><longitudinal outcome studies><longitudinal research study><multi-ethnic><multiethnic><parent><pathway><patient oriented outcomes><personalized care><personalized patient care><precision medicine><precision-based medicine><predict clinical outcome><primary outcome><prognostic ability><prognostic power><prognostic utility><prognostic value><prospective><recruit><renal><renal biopsy><segmental glomerulonephritis><therapeutic immunomodulation><therapeutic immunoregulation><tool><treatment risk>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrew John Karter

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$370,000

FY 2026

Project Title

Evidence-Based Targets for Continuous Glucose Monitoring Metrics in Adults with Type 1 Diabetes

Grant Number:

1R56DK141601-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract: Robust evidence supports the use of continuous glucose monitoring (CGM) to assess glycemic control and inform clinical decisions in adults with type 1 diabetes (T1D). The voluminous raw CGM data (glucose reading every few minutes) is summarized into 8 standard CGM metrics (e.g., time in ra...

Research Terms

<21+ years old><Acute><Adult><Adult Human><Age><American><Blood Vessels><Brittle Diabetes Mellitus><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Clinical><Complication><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Acidosis><Diabetic Complications><Diabetic Ketoacidosis><Diabetic Ketosis><Disease Frequency Surveys><Electronic Health Record><Equilibrium><Event><Expert Opinion><Foundations><Future><Glucose><Goals><Guidelines><Heart Vascular><Hemoglobin><Hypoglycemia><IDDM><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Link><Measures><Metabolic><Microvascular Dysfunction><Modeling><Observational Study><Outcome><Patient-Centered Care><Patients><Persons><Precision care><Public Health><QOL><Quality of life><Reading><Recommendation><Research><Risk><Safety><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Time><Translational Research><Translational Science><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Work><adulthood><ages><balance><balance function><cardiovascular disorder><causal diagram><causal model><circulatory system><clinical decision-making><clinical practice><co-morbid><co-morbidity><cohort><comorbidity><competing risk><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cross-sectional research study><diabetes><diabetes risk><diabetic ketoacidotic><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evidence base><frailty><glycemic control><high risk><high risk group><high risk individual><high risk people><high risk population><high standard><hypoglycemic><hypoglycemic episodes><improved><indexing><individualized care><individualized clinical decision><individualized decision><individualized patient care><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><machine learning based model><machine learning model><microvascular complications><microvascular disease><multi-ethnic><multiethnic><novel><observational research study><observational survey><patient centered><patient oriented><personalized care><personalized clinical decision><personalized data-driven decision><personalized decision><personalized patient care><preference><real world evidence><risk stratification><stratify risk><translation research><translational investigation><type I diabetes><type one diabetes><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kasia Joanna Lipska

KAISER FOUNDATION RESEARCH INSTITUTE, Oakland, CA

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$370,000

FY 2026

Project Title

Evidence-Based Targets for Continuous Glucose Monitoring Metrics in Adults with Type 1 Diabetes

Grant Number:

1R56DK141601-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract: Robust evidence supports the use of continuous glucose monitoring (CGM) to assess glycemic control and inform clinical decisions in adults with type 1 diabetes (T1D). The voluminous raw CGM data (glucose reading every few minutes) is summarized into 8 standard CGM metrics (e.g., time in ra...

Research Terms

<21+ years old><Acute><Adult><Adult Human><Age><American><Blood Vessels><Brittle Diabetes Mellitus><California><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Categories><Clinical><Complication><Complications of Diabetes Mellitus><Continuous Glucose Monitor><Cross-Sectional Studies><Cross-Sectional Survey><D-Glucose><Data><Dextrose><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Acidosis><Diabetic Complications><Diabetic Ketoacidosis><Diabetic Ketosis><Disease Frequency Surveys><Electronic Health Record><Equilibrium><Event><Expert Opinion><Foundations><Future><Glucose><Goals><Guidelines><Heart Vascular><Hemoglobin><Hypoglycemia><IDDM><Insulin-Dependent Diabetes Mellitus><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Link><Measures><Metabolic><Microvascular Dysfunction><Modeling><Observational Study><Outcome><Patient-Centered Care><Patients><Persons><Precision care><Public Health><QOL><Quality of life><Reading><Recommendation><Research><Risk><Safety><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Time><Translational Research><Translational Science><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Work><adulthood><ages><balance><balance function><cardiovascular disorder><causal diagram><causal model><circulatory system><clinical decision-making><clinical practice><co-morbid><co-morbidity><cohort><comorbidity><competing risk><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cross-sectional research study><diabetes><diabetes risk><diabetic ketoacidotic><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evidence base><frailty><glycemic control><high risk><high risk group><high risk individual><high risk people><high risk population><high standard><hypoglycemic><hypoglycemic episodes><improved><indexing><individualized care><individualized clinical decision><individualized decision><individualized patient care><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><machine learning based model><machine learning model><microvascular complications><microvascular disease><multi-ethnic><multiethnic><novel><observational research study><observational survey><patient centered><patient oriented><personalized care><personalized clinical decision><personalized data-driven decision><personalized decision><personalized patient care><preference><real world evidence><risk stratification><stratify risk><translation research><translational investigation><type I diabetes><type one diabetes><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Todd Michael Brusko

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$286,000

FY 2026

Project Title

Using genetics in the selection of candidates for therapies to prevent type 1 diabetes and its progression.

Grant Number:

2R56DK121843-06A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2019

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Our long-term goal is to predict and prevent type 1 diabetes (T1D) and its progression after onset. The overall objective is to integrate genetics into the selection of individuals who will benefit from T1D disease-modifying therapies (DMTs) to prevent progression through preclinical stages of T1D a...

Research Terms

<21+ years old><Address><Adult><Adult Human><Age><Beta Cell><Biological><Brittle Diabetes Mellitus><C-Peptide><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Chronic><Clinical><Clinical Research><Clinical Study><Data><Development><Diabetes Mellitus><Diagnosis><Disease><Disorder><Family><Funding><Gene variant><Genetic><Genetic Models><Genetic Risk><Genotype><Goals><Grant><Health><Heterogeneity><IA-2 antibody><IA-2-autoantibody><IDDM><Immune><Immune Modulation Therapy><Immune Tolerance><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Tolerance><Immunological><Immunologically><Immunologics><Incidence><Individual><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Life><Metabolic><Methods><Mission><Modeling><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Observational Study><Pancreatic beta Cell><Pancreatic β-Cell><Participant><Pathway interactions><Persons><Precision therapeutics><Predicting Risk><Prevention><Prevention trial><Public Health><QOL><Quality of life><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Risk><Risk Assessment><Risk Marker><SNP array><SNP chip><SNP genotyping><Sampling><Science><Single Base Polymorphism><Single Nucleotide Polymorphism><Societies><Structure of beta Cell of islet><Subcellular Process><Sudden-Onset Diabetes Mellitus><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><Testing><Therapy trial><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States National Institutes of Health><Variant><Variation><adulthood><ages><allelic variant><arm><autoimmune attack><autoimmune destruction><autoimmune pathogenesis><biologic><candidate selection><clinical diagnosis><clinical practice><cohort><computer based prediction><connecting peptide><cost effectiveness><developmental><diabetes><diabetes pathogenesis><diabetes risk><drug mechanism><exhaustion><forecasting risk><genetic variant><genome scale><genome-wide><genomewide><genomic variant><immune modulatory intervention><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune system tolerance><immune unresponsiveness><immune-modulation treatment><immunointervention><immunological intervention><immunological paralysis><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><implementation facilitation><improved><individual response><individualized prevention><individualized response><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><islet autoantibody><islet cell antibody><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><novel><observational research study><observational survey><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathway><personalized prevention><polygenic predictors><polygenic scores><pre-clinical><precision prevention><precision therapies><precision treatment><preclinical><predict responsiveness><predict risk><predict risks><predicted risk><predicted risks><predicting response><predicting risks><predictive modeling><predictive risk><predicts risk><preservation><prevent><preventing><response><risk prediction><risk prediction algorithm><risk prediction model><risk predictions><risk predictor><risk predictors><risk/benefit ratio><single nucleotide polymorphism array><single nucleotide polymorphism chip><single nucleotide polymorphism genotyping><single nucleotide variant><therapeutic immunomodulation><therapeutic immunoregulation><thymus derived lymphocyte><trait><type I diabetes><type one diabetes><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Maria Jose Redondo

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$286,000

FY 2026

Project Title

Using genetics in the selection of candidates for therapies to prevent type 1 diabetes and its progression.

Grant Number:

2R56DK121843-06A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2019

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Our long-term goal is to predict and prevent type 1 diabetes (T1D) and its progression after onset. The overall objective is to integrate genetics into the selection of individuals who will benefit from T1D disease-modifying therapies (DMTs) to prevent progression through preclinical stages of T1D a...

Research Terms

<21+ years old><Address><Adult><Adult Human><Age><Beta Cell><Biological><Brittle Diabetes Mellitus><C-Peptide><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Chronic><Clinical><Clinical Research><Clinical Study><Data><Development><Diabetes Mellitus><Diagnosis><Disease><Disorder><Family><Funding><Gene variant><Genetic><Genetic Models><Genetic Risk><Genotype><Goals><Grant><Health><Heterogeneity><IA-2 antibody><IA-2-autoantibody><IDDM><Immune><Immune Modulation Therapy><Immune Tolerance><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Tolerance><Immunological><Immunologically><Immunologics><Incidence><Individual><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Life><Metabolic><Methods><Mission><Modeling><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Observational Study><Pancreatic beta Cell><Pancreatic β-Cell><Participant><Pathway interactions><Persons><Precision therapeutics><Predicting Risk><Prevention><Prevention trial><Public Health><QOL><Quality of life><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Risk><Risk Assessment><Risk Marker><SNP array><SNP chip><SNP genotyping><Sampling><Science><Single Base Polymorphism><Single Nucleotide Polymorphism><Societies><Structure of beta Cell of islet><Subcellular Process><Sudden-Onset Diabetes Mellitus><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><Testing><Therapy trial><Time><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><United States National Institutes of Health><Variant><Variation><adulthood><ages><allelic variant><arm><autoimmune attack><autoimmune destruction><autoimmune pathogenesis><biologic><candidate selection><clinical diagnosis><clinical practice><cohort><computer based prediction><connecting peptide><cost effectiveness><developmental><diabetes><diabetes pathogenesis><diabetes risk><drug mechanism><exhaustion><forecasting risk><genetic variant><genome scale><genome-wide><genomewide><genomic variant><immune modulatory intervention><immune modulatory therapies><immune modulatory treatment><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune system tolerance><immune unresponsiveness><immune-modulation treatment><immunointervention><immunological intervention><immunological paralysis><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory biologics><immunomodulatory therapies><immunomodulatory treatment><immunoregulatory therapy><immunoregulatory treatment><implementation facilitation><improved><individual response><individualized prevention><individualized response><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><islet autoantibody><islet cell antibody><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><novel><observational research study><observational survey><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathway><personalized prevention><polygenic predictors><polygenic scores><pre-clinical><precision prevention><precision therapies><precision treatment><preclinical><predict responsiveness><predict risk><predict risks><predicted risk><predicted risks><predicting response><predicting risks><predictive modeling><predictive risk><predicts risk><preservation><prevent><preventing><response><risk prediction><risk prediction algorithm><risk prediction model><risk predictions><risk predictor><risk predictors><risk/benefit ratio><single nucleotide polymorphism array><single nucleotide polymorphism chip><single nucleotide polymorphism genotyping><single nucleotide variant><therapeutic immunomodulation><therapeutic immunoregulation><thymus derived lymphocyte><trait><type I diabetes><type one diabetes><β-cell><β-cells><βCell>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christina Leigh Stallings

SAINT LOUIS UNIVERSITY, SAINT LOUIS, MO

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$259,125

FY 2026

Project Title

Dissecting the Contribution of Neutrophils to Diabetes/Tuberculosis Comorbidity

Grant Number:

1R21AI197485-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2028

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Diabetes mellitus (DM) is a group of metabolic diseases that affect how the body utilizes glucose and result in elevated levels of glucose in the blood and urine. DM increases the risk of many infections and their complications, but comorbidity with tuberculosis (TB) stands out due to its tremendous...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Applications Grants><Blood><Blood Cells><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Blood Reticuloendothelial System><Blood Sample><Blood Vessels><Blood specimen><Brittle Diabetes Mellitus><Cause of Death><Cell Function><Cell Isolation><Cell Physiology><Cell Process><Cell Segregation><Cell Separation><Cell Separation Technology><Cellular Function><Cellular Immune Function><Cellular Physiology><Cellular Process><Chemicals><Classification><Complex><D-Glucose><Death Rate><Defect><Dextrose><Diabetes Mellitus><Diabetic mouse><Disease><Disease Outcome><Disorder><Drug Targeting><Drug resistance><Drugs><Exhibits><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Foundations><Future><Glucose><Grant Proposals><Human><Humulin R><IDDM><Immune><Immunes><Impaired tissue repair><Impaired wound healing><India><Individual><Infection><Inflammation><Inflammatory><Innate Immune Response><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Interferon Type I><Intermediary Metabolism><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Life><Lung Inflammation><Lung Parenchyma><Lung Tissue><Lymphatic cell><Lymphocyte><Lymphocytic><M tb><M tuberculosis><M tuberculosis infection><M. tb><M. tb infection><M. tuberculosis><M. tuberculosis infection><M.tb infection><M.tuberculosis infection><MTB infection><Macrophage><Marrow Neutrophil><Maturity-Onset Diabetes Mellitus><Mediating><Medication><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Pathway><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modern Man><Monitor><Murine><Mus><Mycobacterium tuberculosis><Mycobacterium tuberculosis (MTB) infection><Mycobacterium tuberculosis infection><Mφ><NIDDM><Neutrophil Activation><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Outcome><Pathogenesis><Patients><Peripheral Blood Cell><Pharmaceutical Preparations><Phenotype><Pneumonitis><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Predisposition><Property><Pulmonary Inflammation><RNA Seq><RNA sequencing><RNAseq><Recurrence><Recurrent><Regular Insulin><Regulation><Reporting><Risk><Sampling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure of parenchyma of lung><Subcellular Process><Sudden-Onset Diabetes Mellitus><Susceptibility><Systematics><Systems Biology><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><TB infection><TB therapy><TB treatment><Testing><Thesaurismosis><Time><Tuberculosis><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type 2 diabetic><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Type II diabetic><Urine><Work><abnormal tissue repair><adaptive immune response><adiposity><adult onset diabetes><adulthood><cell sorting><cell type><co-morbid><co-morbidity><comorbidity><corpulence><delayed wound healing><diabetes><diabetes mouse model><diabetic><disseminated TB><disseminated tuberculosis><drug resistant><drug-sensitive><drug/agent><experience><experiment><experimental research><experimental study><experiments><flow cytophotometry><immune function><infection due to Mycobacterium tuberculosis><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin tolerance><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lymph cell><maturity onset diabetes><metabolism disorder><mortality><mortality rate><mouse model><mtb><murine model><neglect><neutrophil><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathogen><resistance to Drug><resistant to Drug><response><transcriptome sequencing><transcriptomic sequencing><translational study><treat M. tuberculosis><treat Mtb><treat Mycobacterium tuberculosis><treat tb><treat tuberculosis><tuberculosis infection><tuberculosis therapy><tuberculosis treatment><tuberculous spondyloarthropathy><type 1 diabetic><type 2 DM><type I diabetes><type I diabetic><type II DM><type one diabetes><type two diabetes><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ramakrishna Vankayalapati

SAINT LOUIS UNIVERSITY, SAINT LOUIS, MO

Exploratory lead · 40/100

Solid budget

Very recent

Active award

$259,125

FY 2026

Project Title

Dissecting the Contribution of Neutrophils to Diabetes/Tuberculosis Comorbidity

Grant Number:

1R21AI197485-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2026

End Date:

3/31/2028

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Diabetes mellitus (DM) is a group of metabolic diseases that affect how the body utilizes glucose and result in elevated levels of glucose in the blood and urine. DM increases the risk of many infections and their complications, but comorbidity with tuberculosis (TB) stands out due to its tremendous...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Applications Grants><Blood><Blood Cells><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Blood Reticuloendothelial System><Blood Sample><Blood Vessels><Blood specimen><Brittle Diabetes Mellitus><Cause of Death><Cell Function><Cell Isolation><Cell Physiology><Cell Process><Cell Segregation><Cell Separation><Cell Separation Technology><Cellular Function><Cellular Immune Function><Cellular Physiology><Cellular Process><Chemicals><Classification><Complex><D-Glucose><Death Rate><Defect><Dextrose><Diabetes Mellitus><Diabetic mouse><Disease><Disease Outcome><Disorder><Drug Targeting><Drug resistance><Drugs><Exhibits><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Foundations><Future><Glucose><Grant Proposals><Human><Humulin R><IDDM><Immune><Immunes><Impaired tissue repair><Impaired wound healing><India><Individual><Infection><Inflammation><Inflammatory><Innate Immune Response><Insulin><Insulin Resistance><Insulin-Dependent Diabetes Mellitus><Interferon Type I><Intermediary Metabolism><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Life><Lung Inflammation><Lung Parenchyma><Lung Tissue><Lymphatic cell><Lymphocyte><Lymphocytic><M tb><M tuberculosis><M tuberculosis infection><M. tb><M. tb infection><M. tuberculosis><M. tuberculosis infection><M.tb infection><M.tuberculosis infection><MTB infection><Macrophage><Marrow Neutrophil><Maturity-Onset Diabetes Mellitus><Mediating><Medication><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Pathway><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modern Man><Monitor><Murine><Mus><Mycobacterium tuberculosis><Mycobacterium tuberculosis (MTB) infection><Mycobacterium tuberculosis infection><Mφ><NIDDM><Neutrophil Activation><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Outcome><Pathogenesis><Patients><Peripheral Blood Cell><Pharmaceutical Preparations><Phenotype><Pneumonitis><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Predisposition><Property><Pulmonary Inflammation><RNA Seq><RNA sequencing><RNAseq><Recurrence><Recurrent><Regular Insulin><Regulation><Reporting><Risk><Sampling><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Structure of parenchyma of lung><Subcellular Process><Sudden-Onset Diabetes Mellitus><Susceptibility><Systematics><Systems Biology><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><TB infection><TB therapy><TB treatment><Testing><Thesaurismosis><Time><Tuberculosis><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type 2 diabetic><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Type II diabetic><Urine><Work><abnormal tissue repair><adaptive immune response><adiposity><adult onset diabetes><adulthood><cell sorting><cell type><co-morbid><co-morbidity><comorbidity><corpulence><delayed wound healing><diabetes><diabetes mouse model><diabetic><disseminated TB><disseminated tuberculosis><drug resistant><drug-sensitive><drug/agent><experience><experiment><experimental research><experimental study><experiments><flow cytophotometry><immune function><infection due to Mycobacterium tuberculosis><insulin dependent diabetes><insulin dependent type 1><insulin resistant><insulin tolerance><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><lymph cell><maturity onset diabetes><metabolism disorder><mortality><mortality rate><mouse model><mtb><murine model><neglect><neutrophil><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathogen><resistance to Drug><resistant to Drug><response><transcriptome sequencing><transcriptomic sequencing><translational study><treat M. tuberculosis><treat Mtb><treat Mycobacterium tuberculosis><treat tb><treat tuberculosis><tuberculosis infection><tuberculosis therapy><tuberculosis treatment><tuberculous spondyloarthropathy><type 1 diabetic><type 2 DM><type I diabetes><type I diabetic><type II DM><type one diabetes><type two diabetes><vascular>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ormond A MacDougald

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$108,000

FY 2026

Project Title

Michigan Summer Undergraduate Research Experience: Diabetes & Metabolic Diseases

Grant Number:

5R25DK141426-02

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2025

End Date:

1/31/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

To improve health and quality of life for people with diabetes and other endocrine and metabolic disorders; liver and intestinal diseases; and obesity, there is tremendous need for well-trained basic and clinical researchers who further our mechanistic understanding of the molecular and cellular und...

Research Terms

<21+ years old><Absenteeism><Academic Medical Centers><Acceleration><Address><Adult><Adult Human><American><Apoplexy><Area><Basic Research><Basic Science><Biomedical Research><Blindness><Brain Vascular Accident><Cardiovascular Diseases><Cause of Death><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical><Clinical Research><Clinical Study><Communication><Country><Creativeness><Death><Development><Diabetes Mellitus><Diagnosis><Digestive Diseases><Digestive System Diseases><Digestive System Disorders><Discipline><Disease><Disorder><Endocrine Diseases><Endocrine Diseases and Manifestations><Endocrine System Diseases><Endocrinology><Environment><Facilities and Administrative Costs><Faculty><Fostering><Funding><Future><GI tract disorder><Goals><Health><Hepatic Disorder><Incidence><Indirect Costs><Intermediary Metabolism><Intestinal><Intestinal Diseases><Intestinal Disorder><Intestines><Investigators><Kidney Failure><Kidney Insufficiency><Knowledge><Laboratories><Link><Liver><Liver diseases><Lower Extremity><Lower Limb><Medical Care Costs><Membrum inferius><Mentors><Mentorship><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Metabolism and Endocrinology><Michigan><Mission><Molecular><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Obesity><Oral><Pathogenesis><Patients><Persons><Physiology><Prevention><QOL><Qualifying><Quality of life><Renal Failure><Renal Insufficiency><Research><Research Personnel><Research Training><Researchers><Science><Scientist><Series><Source><Stroke><Structure><Students><Talents><Thesaurismosis><Time><Training><Translating><Translational Research><Translational Science><United States><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><Universities><University Medical Centers><Work><adiposity><adulthood><amputated limb><bowel><brain attack><cardiovascular disorder><career><cerebral vascular accident><cerebrovascular accident><college><collegiate><conference><convention><corpulence><cost estimate><cost estimation><creativity><develop therapy><developmental><diabetes><digestive disorder><digestive tract disease><disability><endocrine disorder><experience><gastrointestinal tract disease><gastrointestinal tract disorder><hepatic body system><hepatic disease><hepatic organ system><hepatopathy><improved><interest><intervention development><intestine disease><intestine disorder><lectures><limb amputation><liver disorder><medical costs><medical expenses><metabolism disorder><multidisciplinary><next generation><premature><prematurity><productivity loss><programs><recruit><responsible research conduct><skills><stroked><strokes><student mentoring><student research><student-led learning><student-led research><summer research><summer undergraduate training><summit><symposia><symposium><therapy development><training opportunity><translation research><translational investigation><treatment development><undergrad><undergraduate><undergraduate research experience><undergraduate research opportunities><undergraduate research programs><undergraduate student><undergraduate summer program><undergraduate summer research><vision loss><visual loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Xin Tong

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$108,000

FY 2026

Project Title

Michigan Summer Undergraduate Research Experience: Diabetes & Metabolic Diseases

Grant Number:

5R25DK141426-02

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2025

End Date:

1/31/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

To improve health and quality of life for people with diabetes and other endocrine and metabolic disorders; liver and intestinal diseases; and obesity, there is tremendous need for well-trained basic and clinical researchers who further our mechanistic understanding of the molecular and cellular und...

Research Terms

<21+ years old><Absenteeism><Academic Medical Centers><Acceleration><Address><Adult><Adult Human><American><Apoplexy><Area><Basic Research><Basic Science><Biomedical Research><Blindness><Brain Vascular Accident><Cardiovascular Diseases><Cause of Death><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical><Clinical Research><Clinical Study><Communication><Country><Creativeness><Death><Development><Diabetes Mellitus><Diagnosis><Digestive Diseases><Digestive System Diseases><Digestive System Disorders><Discipline><Disease><Disorder><Endocrine Diseases><Endocrine Diseases and Manifestations><Endocrine System Diseases><Endocrinology><Environment><Facilities and Administrative Costs><Faculty><Fostering><Funding><Future><GI tract disorder><Goals><Health><Hepatic Disorder><Incidence><Indirect Costs><Intermediary Metabolism><Intestinal><Intestinal Diseases><Intestinal Disorder><Intestines><Investigators><Kidney Failure><Kidney Insufficiency><Knowledge><Laboratories><Link><Liver><Liver diseases><Lower Extremity><Lower Limb><Medical Care Costs><Membrum inferius><Mentors><Mentorship><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Metabolism and Endocrinology><Michigan><Mission><Molecular><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Obesity><Oral><Pathogenesis><Patients><Persons><Physiology><Prevention><QOL><Qualifying><Quality of life><Renal Failure><Renal Insufficiency><Research><Research Personnel><Research Training><Researchers><Science><Scientist><Series><Source><Stroke><Structure><Students><Talents><Thesaurismosis><Time><Training><Translating><Translational Research><Translational Science><United States><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><Universities><University Medical Centers><Work><adiposity><adulthood><amputated limb><bowel><brain attack><cardiovascular disorder><career><cerebral vascular accident><cerebrovascular accident><college><collegiate><conference><convention><corpulence><cost estimate><cost estimation><creativity><develop therapy><developmental><diabetes><digestive disorder><digestive tract disease><disability><endocrine disorder><experience><gastrointestinal tract disease><gastrointestinal tract disorder><hepatic body system><hepatic disease><hepatic organ system><hepatopathy><improved><interest><intervention development><intestine disease><intestine disorder><lectures><limb amputation><liver disorder><medical costs><medical expenses><metabolism disorder><multidisciplinary><next generation><premature><prematurity><productivity loss><programs><recruit><responsible research conduct><skills><stroked><strokes><student mentoring><student research><student-led learning><student-led research><summer research><summer undergraduate training><summit><symposia><symposium><therapy development><training opportunity><translation research><translational investigation><treatment development><undergrad><undergraduate><undergraduate research experience><undergraduate research opportunities><undergraduate research programs><undergraduate student><undergraduate summer program><undergraduate summer research><vision loss><visual loss>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lei Yin

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$108,000

FY 2026

Project Title

Michigan Summer Undergraduate Research Experience: Diabetes & Metabolic Diseases

Grant Number:

5R25DK141426-02

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2025

End Date:

1/31/2030

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

To improve health and quality of life for people with diabetes and other endocrine and metabolic disorders; liver and intestinal diseases; and obesity, there is tremendous need for well-trained basic and clinical researchers who further our mechanistic understanding of the molecular and cellular und...

Research Terms

<21+ years old><Absenteeism><Academic Medical Centers><Acceleration><Address><Adult><Adult Human><American><Apoplexy><Area><Basic Research><Basic Science><Biomedical Research><Blindness><Brain Vascular Accident><Cardiovascular Diseases><Cause of Death><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical><Clinical Research><Clinical Study><Communication><Country><Creativeness><Death><Development><Diabetes Mellitus><Diagnosis><Digestive Diseases><Digestive System Diseases><Digestive System Disorders><Discipline><Disease><Disorder><Endocrine Diseases><Endocrine Diseases and Manifestations><Endocrine System Diseases><Endocrinology><Environment><Facilities and Administrative Costs><Faculty><Fostering><Funding><Future><GI tract disorder><Goals><Health><Hepatic Disorder><Incidence><Indirect Costs><Intermediary Metabolism><Intestinal><Intestinal Diseases><Intestinal Disorder><Intestines><Investigators><Kidney Failure><Kidney Insufficiency><Knowledge><Laboratories><Link><Liver><Liver diseases><Lower Extremity><Lower Limb><Medical Care Costs><Membrum inferius><Mentors><Mentorship><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Metabolism and Endocrinology><Michigan><Mission><Molecular><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><Obesity><Oral><Pathogenesis><Patients><Persons><Physiology><Prevention><QOL><Qualifying><Quality of life><Renal Failure><Renal Insufficiency><Research><Research Personnel><Research Training><Researchers><Science><Scientist><Series><Source><Stroke><Structure><Students><Talents><Thesaurismosis><Time><Training><Translating><Translational Research><Translational Science><United States><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><Universities><University Medical Centers><Work><adiposity><adulthood><amputated limb><bowel><brain attack><cardiovascular disorder><career><cerebral vascular accident><cerebrovascular accident><college><collegiate><conference><convention><corpulence><cost estimate><cost estimation><creativity><develop therapy><developmental><diabetes><digestive disorder><digestive tract disease><disability><endocrine disorder><experience><gastrointestinal tract disease><gastrointestinal tract disorder><hepatic body system><hepatic disease><hepatic organ system><hepatopathy><improved><interest><intervention development><intestine disease><intestine disorder><lectures><limb amputation><liver disorder><medical costs><medical expenses><metabolism disorder><multidisciplinary><next generation><premature><prematurity><productivity loss><programs><recruit><responsible research conduct><skills><stroked><strokes><student mentoring><student research><student-led learning><student-led research><summer research><summer undergraduate training><summit><symposia><symposium><therapy development><training opportunity><translation research><translational investigation><treatment development><undergrad><undergraduate><undergraduate research experience><undergraduate research opportunities><undergraduate research programs><undergraduate student><undergraduate summer program><undergraduate summer research><vision loss><visual loss>

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Arshiya Ahmed Baig

UNIVERSITY OF CHICAGO, CHICAGO, IL

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$105,749

FY 2026

Project Title

DULCE (Diabetes InqUiry Through a Learning Collaborative Experience)

Grant Number:

5R25DK130849-04

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/17/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The purpose of the NIDDK R25 Research Education Training Program, DULCE (Diabetes InqUiry through a Learning Collaborative Experience) at the University of Chicago Pritzker School of Medicine is to inspire medical students to pursue careers in diabetes mellitus (DM) research through exposure to the ...

Research Terms

<21+ years old><Address><Admission><Admission activity><Adult><Adult Human><American><Area><Attitude><Basic Research><Basic Science><Caliber><Caring><Chicago><Clinical><Clinical Research><Clinical Study><Communities><Community Health><Dedications><Diabetes Mellitus><Evaluation><Exposure to><Funding><Future><Goals><Grant><Health Occupations><Health Professions><Home><Intention><Investigators><Learning><MD students><Medical Students><Mentors><Modeling><Monitor><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nature><Patient Care><Patient Care Delivery><Patients><Peer Review><Physicians><Policies><Policy Research><Population><Productivity><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Recommendation><Reporting><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Training><Researchers><Role><Scientific Publication><Scientist><Self Efficacy><Series><Specialty><Structure><Students><Technology><Therapeutic><Training><Training Programs><Translational Research><Translational Science><United States><United States National Institutes of Health><Universities><Work><adulthood><assess effectiveness><care for patients><care of patients><career><caring for patients><clinical care><clinical practice><clinical translation><clinically translatable><community-based health><conference><convention><determine effectiveness><diabetes><education research><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><examine effectiveness><experience><health science profession><homes><improved><innovate><innovation><innovative><interdisciplinary collaboration><interest><investigate longitudinal><longitudinal investigation><longitudinal research><medical college><medical school students><medical schools><medical specialties><meeting><meetings><multidisciplinary><new approaches><novel><novel approaches><novel strategies><novel strategy><peer><programs><public data base><public database><publicly accessible data base><publicly accessible database><publicly available data base><publicly available database><school of medicine><social role><student research><student training><student-led research><study longitudinal><summer research><summit><survey longitudinal><symposia><symposium><theories><transdisciplinary collaboration><translation research><translational investigation><work group><working group>

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MARSHALL H CHIN

UNIVERSITY OF CHICAGO, CHICAGO, IL

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$105,749

FY 2026

Project Title

DULCE (Diabetes InqUiry Through a Learning Collaborative Experience)

Grant Number:

5R25DK130849-04

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/17/2023

End Date:

12/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The purpose of the NIDDK R25 Research Education Training Program, DULCE (Diabetes InqUiry through a Learning Collaborative Experience) at the University of Chicago Pritzker School of Medicine is to inspire medical students to pursue careers in diabetes mellitus (DM) research through exposure to the ...

Research Terms

<21+ years old><Address><Admission><Admission activity><Adult><Adult Human><American><Area><Attitude><Basic Research><Basic Science><Caliber><Caring><Chicago><Clinical><Clinical Research><Clinical Study><Communities><Community Health><Dedications><Diabetes Mellitus><Evaluation><Exposure to><Funding><Future><Goals><Grant><Health Occupations><Health Professions><Home><Intention><Investigators><Learning><MD students><Medical Students><Mentors><Modeling><Monitor><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nature><Patient Care><Patient Care Delivery><Patients><Peer Review><Physicians><Policies><Policy Research><Population><Productivity><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Recommendation><Reporting><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Training><Researchers><Role><Scientific Publication><Scientist><Self Efficacy><Series><Specialty><Structure><Students><Technology><Therapeutic><Training><Training Programs><Translational Research><Translational Science><United States><United States National Institutes of Health><Universities><Work><adulthood><assess effectiveness><care for patients><care of patients><career><caring for patients><clinical care><clinical practice><clinical translation><clinically translatable><community-based health><conference><convention><determine effectiveness><diabetes><education research><effectiveness assessment><effectiveness evaluation><evaluate effectiveness><examine effectiveness><experience><health science profession><homes><improved><innovate><innovation><innovative><interdisciplinary collaboration><interest><investigate longitudinal><longitudinal investigation><longitudinal research><medical college><medical school students><medical schools><medical specialties><meeting><meetings><multidisciplinary><new approaches><novel><novel approaches><novel strategies><novel strategy><peer><programs><public data base><public database><publicly accessible data base><publicly accessible database><publicly available data base><publicly available database><school of medicine><social role><student research><student training><student-led research><study longitudinal><summer research><summit><survey longitudinal><symposia><symposium><theories><transdisciplinary collaboration><translation research><translational investigation><work group><working group>

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John Joseph Kopchick

OHIO UNIVERSITY ATHENS, ATHENS, OH

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$102,639

FY 2026

Project Title

Diabetes Institute Summer Interprofessional Research Experience (DISIRE) for Undergraduates

Grant Number:

5R25DK122952-04

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/17/2022

End Date:

12/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Abstract: This proposal seeks to develop a “Diabetes Institute Summer Interprofessional Research Experience (DISIRE) for Undergraduates”. The vision for the DISIRE education program is to increase the number of undergraduates from Appalachian backgrounds who pursue graduate programs in the biologica...

Research Terms

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Molly Nelson

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$49,538

FY 2026

Project Title

Early-Life Microbes Prevent Autoimmune Diabetes by Upregulating PD-1 on T Cells

Grant Number:

1F31DK143738-01A1

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

3/1/2026

End Date:

2/28/2029

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary: Type 1 diabetes (T1D) is a chronic autoimmune disease that affects millions globally, and the incidence of T1D is increasing. Early-life disruptions of the gut microbiome have long-lasting impacts on the risk for developing type 1 diabetes (T1D), yet how the composition of the earl...

Research Terms

<21+ years old><Activities of Daily Living><Activities of everyday life><Address><Adult><Adult Human><Affect><Animals><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Autoimmune Diabetes><Autoimmune Diseases><Autoimmune Status><Autoimmunity><B-Cells><B-Lymphocytes><B-cell><B9 endocrine pancreas><Bacteria><Brittle Diabetes Mellitus><Cell Communication and Signaling><Cell Locomotion><Cell Migration><Cell Movement><Cell Signaling><Cellular Migration><Cellular Motility><Childhood><Childhood diabetes><Children's Hospital><Communication><Communities><Complex><Computer Analysis><Data><Data Analyses><Data Analysis><Development><Diabetes Mellitus><Educational process of instructing><Endocrine Pancreas><Environmental Factor><Environmental Risk Factor><Experimental Designs><Fellowship><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Frequencies><Future><GI microbiome><Genetic><Germ-Free><Gnotobiotic><Gnotobiotics><Goals><Humulin R><IDDM><Immune><Immune response><Immune system><Immunes><Immunologic Technics><Immunologic Techniques><Immunological Technics><Immunological Techniques><Immunology><Immunomodulation><In Vitro><Inbred NOD Mice><Incidence><Institution><Insulin><Insulin-Dependent Diabetes Mellitus><Intracellular Communication and Signaling><Investigation><Investigators><Islands of Langerhans><Islet Cell><Islets of Langerhans><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Laboratories><Life><Lymph Node Reticuloendothelial System><Lymph node proper><Lymphatic nodes><Measures><Mediating><Mentors><Mentorship><Mice><Mice Mammals><Microbe><Miscellaneous Antibiotic><Modeling><Murine><Mus><NOD Mouse><Nesidioblasts><Non-Obese Diabetic Mice><Nonobese Diabetic Mouse><Novolin R><PD 1><PD-1><PD1><Pancreas><Pancreatic><Pancreatic Islets><Pars endocrina pancreatis><Pathway interactions><Patients><Pediatric Hospitals><Pennsylvania><Persons><Philadelphia><Population><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Predisposition><Receptor Protein><Regular Insulin><Research Personnel><Research Resources><Researchers><Resources><Risk><Science><Scientist><Signal Transduction><Signal Transduction Systems><Signaling><Spleen><Spleen Reticuloendothelial System><Structure><Students><Sudden-Onset Diabetes Mellitus><Susceptibility><Systems Development><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><Teaching><Teff cell><Therapeutic><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Universities><Weaning><Work><Writing><adulthood><analog><autoimmune condition><autoimmune disorder><autoimmune reactivity><autoimmunity disease><autoreactive T cell><autoreactivity><biological signal transduction><career><career development><cell motility><chronic autoimmune disease><clinical relevance><clinically relevant><commensal flora><commensal microbes><commensal microbiota><commensal microflora><compare to control><comparison control><computational analyses><computational analysis><computer analyses><daily living function><daily living functionality><data interpretation><develop therapy><developmental><diabetes><diabetes during childhood><diabetes in childhood><diabetes in children><diabetes pathogenesis><digestive tract microbiome><disease risk><disorder risk><effector T cell><enteric microbiome><environmental risk><exhaust><flow cytophotometry><functional ability><functional capacity><gastrointestinal microbiome><gut microbiome><gut-associated microbiome><high dimensionality><high risk><host response><immune modulation><immune regulation><immune system response><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><improved><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><intervention development><intestinal biome><intestinal microbiome><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><lymph gland><lymph nodes><lymphnodes><meeting><meetings><member><microbial><microbial consortia><microbial flora><microbiome><microbiome intervention><microbiome therapeutics><microbiome therapy><microbiome treatment><microbiome-based intervention><microbiome-based therapeutic><microbiome-based therapy><microbiome-based treatment><microbiota><microflora><mouse model><multispecies consortia><murine model><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel><pathway><pediatric><pediatric diabetes><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><programmed cell death 1><programmed cell death protein 1><programmed death 1><programs><receptor><restraint><scRNA sequencing><scRNA-seq><self-reactive T cell><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><skills><sle2><systemic lupus erythematosus susceptibility 2><therapy development><thymus derived lymphocyte><treatment development><type I diabetes><type one diabetes>

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Jordan Keels

BOSTON COLLEGE, CHESTNUT HILL, MA

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$36,309

FY 2026

Project Title

An epidemiological study to investigate the multifactoral nature of diabetes risk among adults with COVID-19 with a genetic and social determinants of health lens

Grant Number:

5F31NR021624-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

This proposal seeks to enhance our understanding of new-onset diabetes in individuals following infection. This study will investigate 1) the prevalence of new-onset diabetes post-infection 2) how individual and external factors influence the development of new-onset diabetes. Study findings will id...

Research Terms

<21+ years old><ARDS><Access to Care><Active Learning><Acute><Acute Respiratory Distress><Acute Respiratory Distress Syndrome><Address><Admission><Admission activity><Adrenal Cortex Hormones><Adult><Adult ARDS><Adult Human><Adult RDS><Adult Respiratory Distress Syndrome><Adult-Onset Diabetes Mellitus><Affect><Airway failure><Beta Cell><Big Data Analytics><Big Data Methods><Big Data Tools><Biological><Blood Vessels><Boston><Brain Vascular><Brittle Diabetes Mellitus><COVID-19><CV-19><Cardiac infarction><Cessation of life><Chronic Disease><Chronic Illness><Collection><Complement><Complement Proteins><Cooperative Learning><Coronavirus Infectious Disease 2019><Corticoids><Corticosteroids><Da Nang Lung><Data><Data Analyses><Data Analysis><Data Bases><Data Science><Databases><Death><Detection><Development><Diabetes Mellitus><Disease><Disorder><Early Diagnosis><Early Intervention><Early identification><Endocrinology><Environment><Event><Experiential Learning><Fellowship><Future><GWA study><GWAS><Genetic><Genetic Determinism><Groups at risk><Health><Health Care><Health Care Costs><Health Care Systems><Health Costs><Health Informatics><Health Services Accessibility><Health Surveys><Heart failure><Hormonal Change><Hyperglycemia><IDDM><Iatrogenesis><Individual><Infection><Inflammation><Injury><Institution><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intensive Care><Intervention><Intervention Strategies><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Kidney Diseases><Knowledge><Link><Long-term infection><Maturity-Onset Diabetes Mellitus><Measurable><Mentors><Mentorship><Meta-Analysis><Metabolic><Metabolic dysfunction><Metabolism and Endocrinology><Methodology><Morbidity><Myocardial Infarct><Myocardial Infarction><NIDDM><NIH><National Institutes of Health><Nature><Nephropathy><Neuropathy><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nurses><Obesity><Outcome><Pancreas><Pancreatic><Pancreatic beta Cell><Pancreatic β-Cell><People at risk><Peripheral Angiopathies><Peripheral Vascular Diseases><Peripheral Vascular Disorder><Persons><Persons at risk><Population><Populations at Risk><Pre-DM><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventative intervention><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Prospective Studies><Public Health><Public Health Informatics><Publishing><QOL><Quality of life><Renal Disease><Reporting><Reproducibility><Research><Research Resources><Resources><Respiratory Failure><Retinal Diseases><Retinal Disorder><Risk><Risk Factors><School Health Nursing><School Nursing><Science><Scientist><Shapes><Shock Lung><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Stiff lung><Structure><Structure of beta Cell of islet><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Techniques><Testing><Training><Translations><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Variant><Variation><Work><access to health services><access to services><access to treatment><accessibility to health services><adiposity><adult onset diabetes><adulthood><autoimmune attack><autoimmune destruction><autoimmune pathogenesis><availability of services><biologic><burden of chronic disease><burden of chronic illness><burden of disease><burden of illness><cardiac failure><cardiac infarct><care access><cerebral vascular><cerebro-vascular><cerebrovascular><chronic disorder><chronic infection><college><collegiate><complementation><consumer informatics><coronary attack><coronary infarct><coronary infarction><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><corpulence><data base><data collected in real world><data driven platform><data interpretation><data platform><developmental><diabetes><diabetes risk><disease burden><early detection><epidemiology research study><epidemiology study><epidemiology survey><experience><experimental analysis><formal learning><genetic determinant><genome database><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><health data><health service access><health services availability><heart attack><heart infarct><heart infarction><hyperglycemic><iatrogenic><iatrogenically><iatrogenicity><improved><injuries><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulin resistant><insulin tolerance><intervention for prevention><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><kidney disorder><learning activity><learning method><learning strategies><learning strategy><lens><lenses><macrovascular complication><macrovascular disease><maturity onset diabetes><mortality><neuropathic><nurse><pancreas beta cell><pancreas β cell><pancreatic b-cell><peripheral blood vessel disorder><persistent infection><population health><pre-diabetes><pre-diabetic><prediabetic><prevention intervention><preventional intervention strategy><preventive intervention><prospective research study><prospective survey><real world data><renal disorder><retina disease><retina disorder><retinopathy><service availability><social factors><social health determinants><stress hyperglycemia><stress-induced hyperglycemia><stress-related hyperglycemia><systematic review><training opportunity><translation><treatment access><type 1 diabetes onset><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><vascular><wet lung><whole genome association analysis><whole genome association study><β-cell><β-cells><βCell>

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Juliann B Burkett

VANDERBILT UNIVERSITY, Nashville, TN

Exploratory lead · 40/100

Training-friendly

Recent

Active award

$34,814

FY 2026

Project Title

Targeting the Opposing Roles of Prostaglandin E2 Receptors, EP3 and EP4, in the Pathogenesis of Type One Diabetes

Grant Number:

5F31DK138714-03

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

3/1/2024

End Date:

2/28/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary/Abstract Type one diabetes (T1D) is an autoimmune condition characterized by the progressive destruction of insulin- producing β cells in the pancreas, leading to onset of clinical hyperglycemia and chronic dysglycemia. T1D can be managed for decades with constant blood glucose monit...

Research Terms

<Adult-Onset Diabetes Mellitus><Affect><Affinity><Antioxidants><Attenuated><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autophagocytosis><Autoregulation><Beta Cell><Blood Glucose><Blood Sugar><Blood leukocyte><Brittle Diabetes Mellitus><Cell Body><Cell Communication and Signaling><Cell Death><Cell Function><Cell Growth in Number><Cell Multiplication><Cell Physiology><Cell Process><Cell Proliferation><Cell Signaling><Cell Survival><Cell Viability><Cell-Mediated Lympholytic Cells><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular Proliferation><Cellular Stress><Cellular Stress Response><Chronic><Class Switching><Class Switchings><Clinical><Clinical Trials><Couples><Cytolytic T-Cell><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><Defect><Dendritic Cells><Development><Diabetes Mellitus><Dinoprostone><Disease><Disease Progression><Disorder><Drug Therapy><Dysfunction><EP4><EP4 receptor><ER stress><Environment><Epididymal Secretory Protein E4><Equation><Exposure to><Fostering><Functional disorder><G-Protein alpha Subunit><G-Protein α Subunit><GTP-Binding Protein alpha Subunits><GTP-Binding Protein α Subunits><Gene Expression><Gene Inactivation><Gene Silencing><H and E><HE4><Health><Hematoxylin and Eosin><Hematoxylin and Eosin Staining Method><Histologic><Histologically><Homeostasis><Human><Humulin R><Hyperglycemia><IDDM><Immune><Immune Regulators><Immune Targeting><Immune infiltrates><Immune mediated therapy><Immune system><Immunes><Immunoglobulin Class Switching><Immunoglobulin Class Switchings><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Immunologically Directed Therapy><Immunomodulation><Immunomodulators><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><Impairment><Inbred NOD Mice><Inflammation><Inflammatory><Inflammatory Response><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Intracellular Communication and Signaling><Invaded><Investigation><Isotype Switching><Isotype Switchings><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Lesion><Leukocytes><Leukocytes Reticuloendothelial System><Ligands><Link><Lipids><Lipoxins><Literature><Lymphatic cell><Lymphocyte><Lymphocytic><Macrophage><Major Epididymis-Specific Protein E4><Marrow leukocyte><Maturity-Onset Diabetes Mellitus><Mediating><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Mφ><NIDDM><NOD Mouse><Natural regeneration><Non obese><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Non-Obese Diabetic Mice><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonobese><Nonobese Diabetic Mouse><Novolin R><Onset of illness><Oxidative Stress><PGE2><PGE2 alpha><PGE2alpha><Pancreas><Pancreatic><Pathogenesis><Pathway interactions><Patients><Peptides><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiological Homeostasis><Physiopathology><Prevention><Process><Production><Proliferating><Prostaglandin E2><Prostaglandin E2 alpha><Prostaglandin E2alpha><Proteins><Putative Protease Inhibitor WAP5><Receptor Protein><Regeneration><Regular Insulin><Resolution><Role><Side><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Staining method><Stains><Stress><Subcellular Process><Sudden-Onset Diabetes Mellitus><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><Veiled Cells><WAP Four-Disulfide Core Domain Protein 2><WAP5><WFDC2><WFDC2 gene><White Blood Cells><White Cell><adult onset diabetes><antagonism><antagonist><attenuate><attenuates><autoimmune attack><autoimmune condition><autoimmune destruction><autoimmune disorder><autoimmune inflammation><autoimmune pathogenesis><autoimmune reactivity><autoimmunity disease><autophagy><autoreactivity><biological adaptation to stress><biological signal transduction><cell stress><cytokine><dJ461P17.6><db/db mouse><developmental><diabetes><diabetes pathogenesis><diabetic><disease onset><disorder onset><drug intervention><drug treatment><endoplasmic reticulum stress><fluorescence imaging><fluorescent imaging><glucometer><glucose meter><glucose monitor><hyperglycemic><immune cell infiltrate><immune microenvironment><immune modulation><immune modulators><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunologic reactivity control><immunomodulatory><immunomodulatory molecules><immunoregulation><immunoregulator><immunoregulatory><immunoregulatory molecules><immunosuppressive activity><immunosuppressive function><immunosuppressive microenvironment><immunosuppressive response><immunosuppressive tumor microenvironment><improved><in vivo><insulin dependent diabetes><insulin dependent type 1><insulitis><intervention design><islet><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><killer T cell><lipid mediator><lymph cell><maturity onset diabetes><mouse model><murine model><necrocytosis><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pathophysiology><pathway><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><preservation><prevent><preventing><prostanoid receptor EP4><protein expression><reactioncrisis><receptor><regenerate><resolutions><response><senescence><senescence and its associated secretory phenotype><senescence associated secretome><senescence associated secretory factors><senescence associated secretory pathway><senescence associated secretory phenotype><senescence associated secretory program><senescence associated secretory proteins><senescent><senescent associated secretome><senescent associated secretory phenotype><social role><stress response><stressreaction><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic target><therapy design><thymus derived lymphocyte><transcriptional silencing><treatment design><tumor immune microenvironment><tumor-immune system interactions><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><white blood cell><white blood corpuscle><β-cell><β-cells><βCell>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ilana Rae Olin

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Exploratory lead · 34/100

Training-friendly

Active award

$54,538

FY 2026

Project Title

Characterizing IgA-microbe interactions in type 1 diabetes

Grant Number:

5F30DK142323-02

Activity Code:

F30

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Type 1 diabetes (T1D) is a chronic autoimmune disease that often emerges during childhood due to T cell- mediated destruction of insulin-producing  cells in the pancreas. Over the last 30 years, the incidence of T1D has increased by 3-4%, a rapid change that cannot be explained by g...

Research Terms

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Zach Cooper

UNIVERSITY OF GEORGIA, ATHENS, GA

Exploratory lead · 34/100

Training-friendly

Active award

$43,828

FY 2026

Project Title

A process evaluation of a pragmatic randomized controlled trial to promote mental health among adults with Type 1 diabetes

Grant Number:

5F31DK141239-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2026

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT People with type 1 diabetes (T1D) have an increased risk of developing depression, yet rarely receive treatment for depression and diabetes simultaneously. The absence of treatment is linked to a reduced chance of achieving target glycemic goals, thereby raising the risk of ...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Assess implementation><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Biological><Brittle Diabetes Mellitus><Caring><Chronic Disease><Chronic Illness><Clinic><Clinical Sciences><Comprehensive Health Care><Conditioning Therapy><Data><Depressive Syndromes><Depressive disorder><Diabetes Mellitus><Diabetic Neuropathies><Diabetic Retinopathy><Effectiveness><Effectiveness of Interventions><Emotional Depression><Environment><Evaluation><Frequencies><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Costs><Health Costs><Hemoglobin A(1)><IDDM><Implementation assessment><Individual><Insulin-Dependent Diabetes Mellitus><Intervention><Interview><Investigators><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Ketosis-Resistant Diabetes Mellitus><Knowledge><Life Style><Lifestyle><Link><Maturity-Onset Diabetes Mellitus><Measures><Medical><Mental Depression><Mental Health><Mental Hygiene><Mental disorders><Mental health disorders><Mental health promotion><Mentors><Mentorship><Methodology><Methods><Modeling><Motivation><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Outcome><Parents><Participant><Patients><Persons><Primary Care><Probabilistic Models><Probability><Probability Models><Psychiatric Disease><Psychiatric Disorder><Psychological Health><QOC><Quality of Care><Questionnaires><Randomized, Controlled Trials><Research><Research Personnel><Researchers><Risk><Self Efficacy><Slow-Onset Diabetes Mellitus><Specialty><Stable Diabetes Mellitus><Statistical Models><Structure><Sudden-Onset Diabetes Mellitus><Survey Instrument><Survey Method><Survey Methodology><Surveys><T1 DM><T1 diabetes><T1D><T1DM><T2 DM><T2D><T2DM><Testing><Theory of Change><Time><Training><Training Support><Translational Research><Translational Science><Treatment outcome><Type 1 Diabetes Mellitus><Type 1 diabetes><Type 2 Diabetes Mellitus><Type 2 diabetes><Type I Diabetes Mellitus><Type II Diabetes Mellitus><Type II diabetes><United States><Universities><Visit><Work><adult onset diabetes><adulthood><behavior intervention><behavioral intervention><biologic><care services><care systems><career><chronic disorder><collaborative care><comprehensive care><cost><depression><depression symptom><depressive><depressive symptoms><diabetes><diabetes risk><diabetes self-care><diabetes self-management><diabetes-associated neuropathy><evaluate implementation><evaluation of implementation><experience><glycemic control><hemoglobin A1c><implementation determinants><implementation evaluation><implementation factors><implementation outcomes><implementation science><improved><insight><insulin dependent diabetes><insulin dependent type 1><integrated care><integrated health care><integrated model of care><intervention participants><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><ketosis resistant diabetes><maturity onset diabetes><medical specialties><meeting><meetings><mental illness><mortality><parent><participant enrollment><patient enrollment><primary care setting><primary outcome><process evaluation><psychiatric illness><psychologic><psychological><psychological disorder><randomized control trial><randomized, clinical trials><secondary analysis><skills><statistical linear mixed models><statistical linear models><translation research><translational investigation><treatment adherence><treatment compliance><type 2 DM><type I diabetes><type II DM><type one diabetes><type two diabetes><uptake>

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Christine March

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 32/100

Solid budget

Recent

Active award

$472,950

FY 2026

Project Title

Technology knowledge optimization for type 1 diabetes in schools (TeKnO T1D: Schools): A Novel e-learning platform for school nurses to advance health outcomes

Grant Number:

1R21NR022207-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/24/2026

End Date:

1/31/2028

Project Abstract

The standard of care for pediatric type 1 diabetes (T1D) is the use of continuous glucose monitoring (CGM) and automated insulin delivery (AID) systems to optimize glycemia. These diabetes technologies hold the potential to decrease the risk of acute and long-term complications. Yet, the rapid devel...

Research Terms

<21+ years old><Abnormal coordination><Access to Care><Active Learning><Acute><Address><Adult><Adult Human><Affect><Brittle Diabetes Mellitus><Care Givers><Care given by nurses><Caregivers><Caring><Child Care><Childhood><Chronic><Chronic Disease><Chronic Illness><Co-ordination disorder><Communities><Continuous Glucose Monitor><Cooperative Learning><Coordination Disorder><Curriculum><Data><Development><Devices><Diabetes Mellitus><Discover Design Build Test><Discover, Design, Build, and Test Framework><Dyscoordination><E-learning><Education><Educational Curriculum><Educational Technology><Educational aspects><Effectiveness><Endocrinology><Enrollment><Experiential Learning><Family><Feedback><Focus Groups><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Costs><Health Care Professional><Health Costs><Health Professional><Health Services Accessibility><Hemoglobin A(1)><Home><Humulin R><Hyperglycemia><IDDM><Incidence><Incoordination><Individual><Insulin><Insulin-Dependent Diabetes Mellitus><Intervention><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Lack of Coordination><Learning><Medical><Metabolism and Endocrinology><Methods><Morbidity><Novolin R><Nurses><Nursing Care><Outcome><Parents><Participant><Patient Self-Report><Perception><Performance><Phase><Population><Privatization><Puericulture><Recommendation><Regular Insulin><Research><Research Resources><Resources><Risk><School Health Nursing><School Nursing><Schools><Self-Report><Structure><Students><Sudden-Onset Diabetes Mellitus><Survey Instrument><Surveys><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Teen><Teenagers><Testing><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Youth><Youth 10-21><acceptability and feasibility><access to health services><access to services><access to treatment><accessibility to health services><adulthood><app based delivery><app delivery><app-delivered><arm><availability of services><care access><child health care><chronic disorder><community partners><community-based partners><computer-assisted instruction><computer-based education><computer-based instruction><computer-based learning><computer-based training><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><design><designing><developmental><diabetes><digital><digital education><digital learning><eLearning><electronic learning><enroll><experience><flexibility><flexible><health in school><health service access><health services availability><hemoglobin A1c><high risk><homes><hyperglycemic><improved><in vivo><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><internet-assisted education><internet-based training><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><lesson plans><mobile application delivered><mobile application delivery><mortality><multimedia learning><novel><nurse><on-line education><on-line learning><online education><online learning><parent><pediatric><pediatric care><pediatric health care><peer><poor health outcome><primary outcome><programs><psychosocial><public health insurance><public insurance><recruit><reduced health outcome><satisfaction><school district><school environment><school health><service availability><social cognitive theory><social learning theory><standard of care><technology-enhanced learning><teen years><teenage><theories><tool><treatment access><type I diabetes><type one diabetes><usability><user centered design><virtual learning><web-based instruction><web-based training><worse health outcome><youth age>

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Seema Meighan

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 32/100

Solid budget

Recent

Active award

$472,950

FY 2026

Project Title

Technology knowledge optimization for type 1 diabetes in schools (TeKnO T1D: Schools): A Novel e-learning platform for school nurses to advance health outcomes

Grant Number:

1R21NR022207-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/24/2026

End Date:

1/31/2028

Project Abstract

The standard of care for pediatric type 1 diabetes (T1D) is the use of continuous glucose monitoring (CGM) and automated insulin delivery (AID) systems to optimize glycemia. These diabetes technologies hold the potential to decrease the risk of acute and long-term complications. Yet, the rapid devel...

Research Terms

<21+ years old><Abnormal coordination><Access to Care><Active Learning><Acute><Address><Adult><Adult Human><Affect><Brittle Diabetes Mellitus><Care Givers><Care given by nurses><Caregivers><Caring><Child Care><Childhood><Chronic><Chronic Disease><Chronic Illness><Co-ordination disorder><Communities><Continuous Glucose Monitor><Cooperative Learning><Coordination Disorder><Curriculum><Data><Development><Devices><Diabetes Mellitus><Discover Design Build Test><Discover, Design, Build, and Test Framework><Dyscoordination><E-learning><Education><Educational Curriculum><Educational Technology><Educational aspects><Effectiveness><Endocrinology><Enrollment><Experiential Learning><Family><Feedback><Focus Groups><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Costs><Health Care Professional><Health Costs><Health Professional><Health Services Accessibility><Hemoglobin A(1)><Home><Humulin R><Hyperglycemia><IDDM><Incidence><Incoordination><Individual><Insulin><Insulin-Dependent Diabetes Mellitus><Intervention><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Knowledge><Lack of Coordination><Learning><Medical><Metabolism and Endocrinology><Methods><Morbidity><Novolin R><Nurses><Nursing Care><Outcome><Parents><Participant><Patient Self-Report><Perception><Performance><Phase><Population><Privatization><Puericulture><Recommendation><Regular Insulin><Research><Research Resources><Resources><Risk><School Health Nursing><School Nursing><Schools><Self-Report><Structure><Students><Sudden-Onset Diabetes Mellitus><Survey Instrument><Surveys><System><T1 DM><T1 diabetes><T1D><T1DM><Technology><Teen><Teenagers><Testing><Time><Training><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Youth><Youth 10-21><acceptability and feasibility><access to health services><access to services><access to treatment><accessibility to health services><adulthood><app based delivery><app delivery><app-delivered><arm><availability of services><care access><child health care><chronic disorder><community partners><community-based partners><computer-assisted instruction><computer-based education><computer-based instruction><computer-based learning><computer-based training><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><cost><design><designing><developmental><diabetes><digital><digital education><digital learning><eLearning><electronic learning><enroll><experience><flexibility><flexible><health in school><health service access><health services availability><hemoglobin A1c><high risk><homes><hyperglycemic><improved><in vivo><innovate><innovation><innovative><insulin dependent diabetes><insulin dependent type 1><internet-assisted education><internet-based training><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><lesson plans><mobile application delivered><mobile application delivery><mortality><multimedia learning><novel><nurse><on-line education><on-line learning><online education><online learning><parent><pediatric><pediatric care><pediatric health care><peer><poor health outcome><primary outcome><programs><psychosocial><public health insurance><public insurance><recruit><reduced health outcome><satisfaction><school district><school environment><school health><service availability><social cognitive theory><social learning theory><standard of care><technology-enhanced learning><teen years><teenage><theories><tool><treatment access><type I diabetes><type one diabetes><usability><user centered design><virtual learning><web-based instruction><web-based training><worse health outcome><youth age>

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THOMAS DELONG

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Exploratory lead · 32/100

Solid budget

Recent

Active award

$429,000

FY 2026

Project Title

Species-Specific Regulation of Autoantigen Processing: A Humanized Mouse Model of Cathepsin D in Type 1 Diabetes

Grant Number:

1R21AI196871-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2026

End Date:

1/31/2028

Project Abstract

ABSTRACT Type 1 diabetes is an autoimmune disease where the immune system mistakenly attacks and destroys insulin-producing beta cells in the pancreas. Our research has discovered unique hybrid molecules, called Hybrid Insulin Peptides (HIPs), that form in beta cells when fragments of insulin fuse w...

Research Terms

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Michael S German

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 30/100

Very recent

Active award

$164,000

FY 2026

Project Title

IL17 Signaling in Monogenic Type 1 Diabetes

Grant Number:

5R21AI191139-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/25/2025

End Date:

3/31/2027

Why this may be worth a closer look

• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract This proposal’s objective is to determine whether genetic mutations that alter IL-17 signaling contribute to the etiology of autoimmune diabetes. Autoimmune diabetes is characterized by circulating autoantibodies and infiltrating autoreactive lymphocytes into the pancreatic ...

Research Terms

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Katie Whytock

ADVENTHEALTH ORLANDO, ORLANDO, FL

Exploratory lead · 22/100

Recent

Active award

$248,322

FY 2026

Project Title

Determining cell- and spatially-distinct skeletal muscle transcriptional aberrations in insulin resistance and type 2 diabetes

Grant Number:

4R00DK135915-03

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2026

End Date:

2/28/2029

Project Abstract

Type 2 Diabetes (T2D) is estimated to affect over 30 million US adults and skeletal muscle (SkM) insulin resistance (IR) is one of the primary aberrations. SkM is a complex organ comprised of different cell types including: myofibers, endothelial cells (EC), smooth muscle cells, fibro-adipogenic pro...

Research Terms

<21+ years old><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Area><Biopsy><Blood Vessels><Body Tissues><Capillary Endothelial Cell><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Complex><Control Groups><D-Glucose><Development><Dextrose><Dissociation><Endothelial Cells><Euglycemic Clamping><Euglycemic-hyperinsulinemic Clamp><Expression Signature><Future><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profile><Gene Expression Profiling><Gene Transcription><Genes><Genetic Transcription><Glucose><Glucose Clamp><Human><Humulin R><Hyperinsulinemic Clamp><Immune><Immunes><Indirect Calorimetry><Individual><Inflammatory><Insulin><Insulin Resistance><Intervention><Intracellular Communication and Signaling><Isotopes><Ketosis-Resistant Diabetes Mellitus><Leanness><Leiomyocyte><Length><Location><Maturity-Onset Diabetes Mellitus><Modern Man><Molecular Target><Mononuclear><Muscle><Muscle Fibers><Muscle Tissue><Muscle satellite cell><Myotubes><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Obesity><Organ><Participant><Perfusion><Population><RNA Expression><Regular Insulin><Research><Resolution><Respiration Calorimetry><Rhabdomyocyte><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Skeletal Fiber><Skeletal Muscle><Skeletal Muscle Cell><Skeletal Muscle Fiber><Skeletal Myocytes><Slow-Onset Diabetes Mellitus><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><Therapeutic Intervention><Thinness><Time><Tissues><Tracer><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Voluntary Muscle><adiposity><adult onset diabetes><adulthood><analyze gene expression><arteriole><biological signal transduction><cell type><corpulence><cytokine><design><designing><developmental><gene expression analysis><gene expression assay><gene expression pattern><gene expression signature><gene network><global gene expression><global transcription profile><glucose disposal><glucose uptake><in vivo><innovate><innovation><innovative><insulin resistant><insulin sensitivity><insulin signaling><insulin stimulated glucose disposal><insulin tolerance><intervention therapy><ketosis resistant diabetes><maturity onset diabetes><muscular><novel><prevent><preventing><progenitor><resolutions><response><satellite cell><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><transcriptional profile><transcriptional profiling><transcriptional signature><transcriptome><type 2 DM><type II DM><type two diabetes><vascular>

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Evan L Reynolds

HENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, EAST LANSING, MI

Exploratory lead · 22/100

Recent

Active award

$247,787

FY 2026

Project Title

Predicting complications of diabetes with longitudinal metabolic trajectories

Grant Number:

5R00DK129785-05

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/8/2022

End Date:

3/31/2027

Project Abstract

ABSTRACT The prevalence of diabetes is increasing worldwide, with an estimated 463 million cases in 2019 (31 million cases in the United States). Patients with diabetes suffer from a number of common and morbid complications, including peripheral neuropathy (PN) and chronic kidney disease (CKD). In ...

Research Terms

<Adult-Onset Diabetes Mellitus><Affect><Age><Akimel O'odham><Algorithms><American Indian Population><American Indian group><American Indian individual><American Indian people><American Indians><Body Weight decreased><Characteristics><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Data><Complex><Complication><Complications of Diabetes Mellitus><Data><Data Bases><Data Scientist><Data Set><Databases><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diagnosis><Disease><Disorder><Drugs><Exercise><Future><Goals><Groups at risk><Health system><Heterogeneity><Impairment><Incidence><Individual><Integrated Health Care Systems><Intervention><Investigators><Ketosis-Resistant Diabetes Mellitus><Knowledge><Lead><Maturity-Onset Diabetes Mellitus><Measurement><Medical><Medication><Mentors><Metabolic><Metabolic Control><Metabolic dysfunction><Metabolic syndrome><NIDDM><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><PNS Diseases><Patients><Pb element><People at risk><Peripheral Nerve Diseases><Peripheral Nervous System Diseases><Peripheral Nervous System Disorders><Peripheral Neuropathy><Persons at risk><Pharmaceutical Preparations><Phase><Phenotype><Physiology><Pima Indian><Population><Populations at Risk><Prevalence><QOL><Quality of life><Research Personnel><Researchers><Risk><Risk Factors><Sample Size><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Statistical Methods><Symptoms><T2 DM><T2D><T2DM><Techniques><Testing><Time><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><United States Department of Veterans Affairs><United States Veterans Administration><Veterans><Veterans Administration><Veterans Affairs><Weight Loss><Weight Reduction><adult onset diabetes><ages><analytical tool><body weight loss><chronic kidney disease><cohort><complex data><damage to kidney><data base><data warehouse><depository><developmental><diabetes><drug/agent><feature extraction><flexibility><flexible><heavy metal Pb><heavy metal lead><improved><innovate><innovation><innovative><integrated health system><integrated system of care><ketosis resistant diabetes><kidney damage><large scale data><large scale data sets><large scale datasets><large-scale data base><large-scale database><life span><lifespan><machine learned algorithm><machine learning algorithm><machine learning based algorithm><machine learning prediction algorithm><maturity onset diabetes><metabolic phenotype><metabolic profile><metabotype><nerve damage><novel><prevent><preventing><rate of change><renal damage><repository><statistic methods><type 2 DM><type II DM><type two diabetes><weight loss intervention><weight loss therapy><weight loss treatment><wt-loss>

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Jacqueline Anne Seiglie

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Exploratory lead · 22/100

Recent

Active award

$123,750

FY 2026

Project Title

Audible diabetesRx: An audio-based digital tool to address health literacy barriers to medication adherence in type 2 diabetes

Grant Number:

1R03DK145781-01

Activity Code:

R03

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/4/2026

End Date:

1/31/2028

Project Abstract

PROJECT SUMMARY Background: Latino adults in the U.S. have higher prevalence of type 2 diabetes (T2D) and mean HbA1c and are nearly twice as likely to report suboptimal adherence to diabetes medications as non-Hispanic White individuals. Low heath literacy (prevalent among ~40% of U.S. Latino adults...

Research Terms

<21+ years old><5th grade><Address><Adherence><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Chronic><Communication challenge><Communication difficulty><Communities><Complications of Diabetes Mellitus><Data><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Diminished Vision><Dose><Drugs><Education><Educational aspects><English Language><Enrollment><Espanol><Feedback><Focus Groups><Future><Glycohemoglobin A><Glycosylated hemoglobin A><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><High Prevalence><Individual><Intervention><Ketosis-Resistant Diabetes Mellitus><Knowledge><Label><Language><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Low Vision><Maturity-Onset Diabetes Mellitus><Medication><Methodology><NIDDM><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Parents><Partial Sight><Participant><Patients><Persons><Pharmaceutical Preparations><Pharmacies><Pharmacists><Pharmacy facility><Population><Questionnaires><Reader><Reading><Recommendation><Reduced Vision><Regimen><Reporting><Research><Role><SMS support><Self Efficacy><Self Management><Self Medication><Slow-Onset Diabetes Mellitus><Spanish><Speech><Stable Diabetes Mellitus><Subnormal Vision><T2 DM><T2D><T2DM><Techniques><Technology><Testing><Text><Text Messaging><Titrations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States><Visual impairment><Writing><acceptability and feasibility><adult onset diabetes><adulthood><behavior adherence><behavioral adherence><compliance behavior><design><designing><determine efficacy><diabetes><diabetes management><diabetes mellitus management><diabetes self-care><diabetes self-management><diabetic management><digital><digital health><digital tool><digital toolkit><drug adherence><drug compliance><drug/agent><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><enroll><evaluate efficacy><examine efficacy><fifth grade><glycemic control><health IT><health information technology><health literacy><hemoglobin A1c><improved><inadequate health literacy><intervention refinement><ketosis resistant diabetes><literacy><low health literacy><maturity onset diabetes><medication adherence><medication compliance><mortality><novel><parent><participant enrollment><patient centered><patient enrollment><patient oriented><poor health literacy><prototype><recruit><reduced health literacy><retention rate><retention strategy><secondary outcome><short message service><side effect><sms messaging><social role><support tools><text based support><text messaging support><texting><texting support><tool><type 2 DM><type II DM><type two diabetes><usability><user centered design><vision impairment><visually impaired>

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Karlijn Anna Catharina Meeks

UNIVERSITY OF MARYLAND BALTIMORE, BALTIMORE, MD

Exploratory lead · 16/100

Active award

$242,695

FY 2026

Project Title

Unravelling the Role of Epigenetics and Cytokines in Type 2 Diabetes among African-ancestry Populations

Grant Number:

5R00DK131018-04

Activity Code:

R00

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2025

End Date:

1/31/2028

Project Abstract

PROJECT SUMMARY/ABSTRACT African-ancestry populations in the US and Europe are disproportionately affected by type 2 diabetes (T2D), while rates are rapidly increasing in sub-Saharan Africa. The reasons for this disproportionate burden are poorly understood but are thought to be a complex interplay ...

Research Terms

<3'-5'-CpG><ACRP30 protein><Adult-Onset Diabetes Mellitus><Affect><Africa><Africa South of the Sahara><African><African ancestry><African descent><Alcohol Drinking><Alcohol consumption><Automobile Driving><Award><BMI><BMI percentile><BMI z-score><Back><Beta Cell><Binding><Biology><Body mass index><CG-dinucleotide><Cardiometabolic Disease><Cardiometabolic Disorder><Causality><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Clinical><Complex><CpG dinucleotide><DNA><DNA Methylation><Data><Deoxyribonucleic Acid><Detection><Development><Diabetes Mellitus><Dorsum><Dysfunction><Environment><Environmental Factor><Environmental Risk Factor><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><EtOH drinking><EtOH use><Ethnic Origin><Ethnicity><Etiology><Europe><European ancestry><Functional disorder><GWA study><GWAS><Gastric Inhibitory Polypeptide><Gene Expression><Gene variant><Genes><Genetic><Genomic medicine><Genomics><Genotype><Glucose-Dependent Insulin-Releasing Peptide><Glucose-Dependent Insulinotropic Peptide><Goals><IL-1ra><IL1 febrile inhibitor><IL1RN><Individual><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Interleukin-1 Receptor Antagonist><Investigators><Ketosis-Resistant Diabetes Mellitus><Knowledge><Lead><Least Squares><Least-Squares Analyses><Least-Squares Analysis><Life Style><Lifestyle><Maps><Maryland><Maturity-Onset Diabetes Mellitus><Mediating><Mediation><Mediator><Mendelian randomization><Mentors><Metabolic><Methods><Migrant><Molecular Interaction><Multiomic Data><NHGRI><NIDDM><National Center for Human Genome Research><National Human Genome Research Institute><Negotiating><Negotiation><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Pathogenesis><Pathway interactions><Pb element><Phase><Physiopathology><Play><Population><Population Heterogeneity><Prevalence><Preventive><Proteins><Publishing><QTL><Quantitative Trait Loci><Quetelet index><RNA Seq><RNA sequencing><RNAseq><Regulation><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Assessment><Role><Rural><Sampling><Site><Slow-Onset Diabetes Mellitus><Smoking Status><Stable Diabetes Mellitus><Sub-Saharan Africa><Subcellular Process><Subsaharan Africa><System><T2 DM><T2D><T2DM><Testing><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Universities><Variant><Variation><Weight><West African><Work><adipocyte complement-related protein 30-kDa><adipocyte, C1q and collagen domain containing protein><adiponectin><adiposity><adult onset diabetes><alcohol ingestion><alcohol intake><alcohol product use><alcohol use><alcoholic beverage consumption><alcoholic drink intake><allelic variant><anakinra><apM-1 protein><apM1 (adipose-specific) protein><career><causation><chromatin remodeling><cohort><corpulence><cytidine monophosphate guanosine><cytidylyl-3'-5'-guanosine><cytokine><cytosine-guanine dinucleotide><develop therapy><developmental><diabetes><disease causation><diverse populations><driving><entire genome><environmental risk><epidemiology research study><epidemiology study><epidemiology survey><epigenetic biomarker><epigenetic marker><epigenetically><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol use><full genome><gastric inhibitory peptide><genetic epidemiologic study><genetic epidemiology><genetic variant><genome medicine><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic variant><global health><health equity><heavy metal Pb><heavy metal lead><heterogeneous population><histone modification><improved><insight><insulin resistant><insulin sensitivity><insulin tolerance><interest><interleukin 1 receptor antagonist protein><intervention development><ketosis resistant diabetes><life-style factor><lifestyle factors><low-frequency mutation><maturity onset diabetes><metabolism measurement><metabolomics><metabonomics><methyl group><methylation biomarker><methylation marker><multiomics><multiple omic data><multiple omics><novel><panomics><pathophysiology><pathway><pleiotropic effect><pleiotropism><pleiotropy><polygenic predictors><polygenic scores><population diversity><public health intervention><rare allele><rare mutation><rare variant><skills><social role><therapy development><transcriptome sequencing><transcriptomic sequencing><treatment development><type 2 DM><type II DM><type two diabetes><urine IL-1 inhibitor><urine interleukin 1 inhibitor><urine-derived IL1 inhibitor><variant of interest><weights><whole genome><whole genome association analysis><whole genome association study><β-cell><β-cells><βCell>

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Karla Ivette Galaviz

TRUSTEES OF INDIANA UNIVERSITY, BLOOMINGTON, IN

Exploratory lead · 16/100

Active award

$198,125

FY 2026

Project Title

Mobile pop-up units for diabetes prevention among Hispanics in rural Indiana

Grant Number:

5R21DK136084-03

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

11/30/2026

Project Abstract

ABSTRACT Type 2 diabetes disproportionately affects rural Hispanic populations in the US. Although the prevalence of diabetes is higher in rural Hispanics than in non-Hispanic Whites, rural Hispanics have limited access to evidence-based diabetes preventive services. Hispanics are less likely to rec...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Agreement><American><BMI><BMI percentile><BMI z-score><Blood Glucose><Blood Sugar><Blood capillaries><Body mass index><Breathing><Chronic Disease><Chronic Illness><Clinic><Clinical><Collaborations><Communities><Community Health Aides><Community Participation><Counseling><County><Data><Diabetes Mellitus><Diabetes prevention><Disparities><Disparity><Epidemic><Evidence based practice guidelines><Exploration, Preparation, Implementation, and Sustainability><Exploration, Preparation, Implementation, and Sustainment><Face><Feedback><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Costs><Health Costs><Hemoglobin A(1)><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Hybrids><Immersion><Indiana><Individual><Individuals from minority><Individuals of minority><Intervention><Interview><Ketosis-Resistant Diabetes Mellitus><Language><Letters><Link><Low income><Maturity-Onset Diabetes Mellitus><Measurement><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Mission><Mobile Health Units><Modeling><Motor Vehicles><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Obesity><Overweight><Participant><Personal Satisfaction><Population><Preparation><Prevalence><Preventative intervention><Preventative screening><Preventative service><Preventive><Preventive screening><Preventive service><Process><Questionnaires><Quetelet index><Recommendation><Research><Research Priority><Research Resources><Resources><Respiratory Aspiration><Respiratory Inspiration><Risk><Risk Reduction><Rural><Rural Health><Sampling><Screening Result><Services><Slow-Onset Diabetes Mellitus><Spanish/English><Stable Diabetes Mellitus><Strategic Planning><Structure><T2 DM><T2D><T2DM><Tablets><Testing><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><U.S. Preventative Services Task Force><U.S. Preventative Task Force><U.S. Preventive Services Task Force><U.S. Preventive Task Force><US Preventative Services Task Force><US Preventative Task Force><US Preventive Health Services Task Force><US Preventive Services Task Force><US Preventive Task Force><USPSTF><Uninsured><United States Preventative Services Task Force><United States Preventative Task Force><United States Preventive Services Task Force><United States Preventive Task Force><Universities><Visit><Vulnerable Populations><Work><access disparities><access to health care><accessibility disparities><accessibility of health care><accessibility to health care><adiposity><adult onset diabetes><adulthood><aged><bilingual><bilingualism><capillary><chronic disorder><community engaged approach><community engaged approaches><community engaged strategies><community engaged strategy><community engagement><community health worker><community partnered approach><community partnered strategy><community partners><community setting><community-based partners><corpulence><cost><design><designing><diabetes><diabetes risk><disparities in access><effectiveness testing><engagement with communities><evidence base><evidence based guidelines><evidence based recommendations><faces><facial><health care access><health care availability><health care service access><health care service availability><hemoglobin A1c><high risk group><high risk individual><high risk people><high risk population><human centered design><implementation research><inequality in access><inequity in access><inequity in accessibility><inspiration><intervention for prevention><iterative design><ketosis resistant diabetes><maturity onset diabetes><minority communities><minority health><novel><outreach><pilot test><preference><preparations><prevention intervention><preventional intervention strategy><preventive intervention><prototype><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><rural Hispanic><rural counties><rural locality><rural place><rural setting><screening><screenings><socio-economic><socio-economically><socioeconomically><socioeconomics><success><tool><type 2 DM><type II DM><type two diabetes><vulnerable group><vulnerable individual><vulnerable people><well-being><wellbeing>

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Ines Gonzalez Casanova

TRUSTEES OF INDIANA UNIVERSITY, BLOOMINGTON, IN

Exploratory lead · 16/100

Active award

$198,125

FY 2026

Project Title

Mobile pop-up units for diabetes prevention among Hispanics in rural Indiana

Grant Number:

5R21DK136084-03

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

11/30/2026

Project Abstract

ABSTRACT Type 2 diabetes disproportionately affects rural Hispanic populations in the US. Although the prevalence of diabetes is higher in rural Hispanics than in non-Hispanic Whites, rural Hispanics have limited access to evidence-based diabetes preventive services. Hispanics are less likely to rec...

Research Terms

<21+ years old><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Agreement><American><BMI><BMI percentile><BMI z-score><Blood Glucose><Blood Sugar><Blood capillaries><Body mass index><Breathing><Chronic Disease><Chronic Illness><Clinic><Clinical><Collaborations><Communities><Community Health Aides><Community Participation><Counseling><County><Data><Diabetes Mellitus><Diabetes prevention><Disparities><Disparity><Epidemic><Evidence based practice guidelines><Exploration, Preparation, Implementation, and Sustainability><Exploration, Preparation, Implementation, and Sustainment><Face><Feedback><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Guidelines><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Care Costs><Health Costs><Hemoglobin A(1)><Hispanic><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Hybrids><Immersion><Indiana><Individual><Individuals from minority><Individuals of minority><Intervention><Interview><Ketosis-Resistant Diabetes Mellitus><Language><Letters><Link><Low income><Maturity-Onset Diabetes Mellitus><Measurement><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Mission><Mobile Health Units><Modeling><Motor Vehicles><NIDDK><NIDDM><National Institute of Diabetes and Digestive and Kidney Diseases><Non-Hispanic><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Nonhispanic><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Not Hispanic or Latino><Obesity><Overweight><Participant><Personal Satisfaction><Population><Preparation><Prevalence><Preventative intervention><Preventative screening><Preventative service><Preventive><Preventive screening><Preventive service><Process><Questionnaires><Quetelet index><Recommendation><Research><Research Priority><Research Resources><Resources><Respiratory Aspiration><Respiratory Inspiration><Risk><Risk Reduction><Rural><Rural Health><Sampling><Screening Result><Services><Slow-Onset Diabetes Mellitus><Spanish/English><Stable Diabetes Mellitus><Strategic Planning><Structure><T2 DM><T2D><T2DM><Tablets><Testing><Training><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><U.S. Preventative Services Task Force><U.S. Preventative Task Force><U.S. Preventive Services Task Force><U.S. Preventive Task Force><US Preventative Services Task Force><US Preventative Task Force><US Preventive Health Services Task Force><US Preventive Services Task Force><US Preventive Task Force><USPSTF><Uninsured><United States Preventative Services Task Force><United States Preventative Task Force><United States Preventive Services Task Force><United States Preventive Task Force><Universities><Visit><Vulnerable Populations><Work><access disparities><access to health care><accessibility disparities><accessibility of health care><accessibility to health care><adiposity><adult onset diabetes><adulthood><aged><bilingual><bilingualism><capillary><chronic disorder><community engaged approach><community engaged approaches><community engaged strategies><community engaged strategy><community engagement><community health worker><community partnered approach><community partnered strategy><community partners><community setting><community-based partners><corpulence><cost><design><designing><diabetes><diabetes risk><disparities in access><effectiveness testing><engagement with communities><evidence base><evidence based guidelines><evidence based recommendations><faces><facial><health care access><health care availability><health care service access><health care service availability><hemoglobin A1c><high risk group><high risk individual><high risk people><high risk population><human centered design><implementation research><inequality in access><inequity in access><inequity in accessibility><inspiration><intervention for prevention><iterative design><ketosis resistant diabetes><maturity onset diabetes><minority communities><minority health><novel><outreach><pilot test><preference><preparations><prevention intervention><preventional intervention strategy><preventive intervention><prototype><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><rural Hispanic><rural counties><rural locality><rural place><rural setting><screening><screenings><socio-economic><socio-economically><socioeconomically><socioeconomics><success><tool><type 2 DM><type II DM><type two diabetes><vulnerable group><vulnerable individual><vulnerable people><well-being><wellbeing>

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Joseph Michael Wallace

RLR VA MEDICAL CENTER, INDIANAPOLIS, IN

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Improving bone mass and quality in comorbid diabetes and chronic kidney disease

Grant Number:

5I01BX005990-04

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

1/1/2023

End Date:

12/31/2026

Project Abstract

PROJECT SUMMARY Diabetes and chronic kidney disease (CKD) consistently rank among the top ten chronic conditions in the United States in terms of prevalence and mortality. US veterans develop diabetes and CKD at an alarming rate, and comorbidity is twice as common in veterans compared with the gener...

Research Terms

<1H-Purin-6-amine><Address><Adenine><Adverse Late Effects><Age><Age of Onset><Animal Disease Models><Animal Model><Animal Models and Related Studies><Biochemical><Biochemical Markers><Biochemistry><Biological Chemistry><Biology><Body Tissues><Bone Diseases><Bone Formation><Bone Tissue><Cell Body><Cells><Chronic><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Collagen><Combined Modality Therapy><Complex><Coupled><Data><Defect><Diabetes Mellitus><Disease><Disorder><Drugs><Estrogens><Exclusion><Exhibits><FDA licensed drugs><FDA-approved agents><FDA-approved drug><FDA-approved medications><FDA-approved pharmaceuticals><FDA-approved therapeutic agent><Food and Drug Administration approved drug><Food and Drug Administration approved medications><Food and Drug Administration approved pharmaceuticals><Fracture><General Population><General Public><Glucose tolerance test><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Hemoglobin A(1)><Histology><Humulin R><Hydration><Hydration status><IPGTT><IR/UV/Raman Spectroscopy><Individual><Insulin><Intervention><Keoxifene><Kidney><Kidney Urinary System><Late Effects><Measures><Mechanics><Medication><Mice><Mice Mammals><Minerals><Modeling><Molecular><Multimodal Therapy><Multimodal Treatment><Multiscale Mechanics><Murine><Mus><Musculoskeletal><Novolin R><Onset of illness><Osteogenesis><Outcome><Pancreatic beta Cell><Pancreatic β-Cell><Patients><Persons><Pharmaceutical Agent><Pharmaceutical Preparations><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Population><Prevalence><Property><Raloxifene><Raman Spectroscopy><Raman Spectrum Analysis><Raman imaging><Raman spectrometry><Regular Insulin><Resistance><Resistance development><Resistant development><Risk><STZ><Severity of illness><Skeleton><Streptozocin><Streptozotocin><Structure of beta Cell of islet><Sum><Testing><Therapeutic><Therapeutic Estrogen><Tissues><Translating><Treatment Protocols><Treatment Regimen><Treatment Schedule><United States><Veterans><Vitamin B4><Work><Zanosar><aged><aged mice><aged mouse><ages><bone><bone disorder><bone fracture><bone mass><bone quality><bone tissue formation><chronic kidney disease><co-morbid><co-morbidity><combination therapy><combined modality treatment><combined treatment><comorbidity><compare intervention><comparison intervention><death risk><developing resistance><diabetes><disease duration><disease length><disease model><disease onset><disease severity><disorder model><disorder onset><drug/agent><elderly mice><experiment><experimental research><experimental study><experiments><fracture risk><glucometer><glucose meter><glucose monitor><hemoglobin A1c><illness length><improved><in vivo><insulin sensitivity test><insulin tolerance test><insulin-induced hypoglycemia test><intraperitoneal glucose tolerance test><mechanic><mechanical><mechanical load><mechanical properties><military veteran><model of animal><mortality><mortality risk><mouse model><multi-modal therapy><multi-modal treatment><multi-scale mechanics><murine model><nano indentation><nanoindentation><novel><old mice><pancreas beta cell><pancreas β cell><pancreatic b-cell><pharmaceutical><physical property><prevent><preventing><renal><resistant><sex><skeletal><skeletal disease><skeletal disorder><skeletons><structural imaging><veteran population>

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TODD M HULGAN

VETERANS HEALTH ADMINISTRATION, NASHVILLE, TN

Exploratory lead · 16/100

Active award

$0

FY 2026

Project Title

Defining the Contribution of Mitochondrial DNA to Viral Infectious Diseases, Type 2 Diabetes, and their Interactions

Grant Number:

5I01BX006162-04

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

1/1/2023

End Date:

12/31/2026

Project Abstract

Mitochondria are at the intersection of metabolism and immunity. Mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) variants affect mitochondrial function and diseases relevant to Veterans. This project includes a team with extensive experience studying the genetics of type 2 diabetes mellitus (T2D) a...

Research Terms

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Michelle E Kimple

WM S. MIDDLETON MEMORIAL VETERANS HOSP, MADISON, WI

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

G protein mediated mechanisms of beta-cell compensation and failure in type 2 diabetes

Grant Number:

5I01BX005804-04

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

10/1/2022

End Date:

9/30/2026

Project Abstract

Diabetes is a costly and complex chronic illness and a serious public health problem. Currently, the prevalence of diabetes in the VA patient population is approximately 25%, with many more Veterans at risk for diabetes due to obesity, aging, and poor lifestyle, as well as exposure to known diabetog...

Research Terms

<0-11 years old><3'5'-cyclic ester of AMP><3,5 cyclic AMP synthetase><Adenosine Cyclic 3',5'-Monophosphate><Adenosine Cyclic Monophosphate><Adenosine, cyclic 3',5'-(hydrogen phosphate)><Adenyl Cyclase><Adenylate Cyclase><Adenylyl Cyclase><Adult-Onset Diabetes Mellitus><Aging><Agonist><Ally><Alpha Cell><Arachidonic Acids><Autocrine Systems><Beta Cell><Blood Circulation><Blood Glucose><Blood Sugar><Bloodstream><Body Tissues><CCK><Caring><Causality><Cell Body><Cell Communication and Signaling><Cell Death><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chemicals><Child><Child Youth><Children (0-21)><Cholecystokinin><Chronic Disease><Chronic Illness><Compensation><Complex><Coupled><Critical Paths><Critical Pathways><Cyclic AMP><Cytoplasm><D-Glucose><Data><Dextrose><Diabetes Mellitus><Diabetes prevention><Dinoprostone><Drugs><Dysfunction><Endocrine Gland Secretion><Etiology><Exposure to><Expression Signature><Failure><Functional disorder><G-Protein alpha Subunit><G-Protein α Subunit><G-Proteins><GLP-1><GLP-1 receptor><GLP-I receptor><GTP-Binding Protein alpha Subunits><GTP-Binding Protein α Subunits><GTP-Binding Proteins><GTP-Regulatory Proteins><Gene Expression Profile><General Population><General Public><Generalized Growth><Genes><Genetic><Glp-1><Glucagon Cell><Glucagon Secreting Cell><Glucose><Goals><Growth><Guanine Nucleotide Coupling Protein><Guanine Nucleotide Regulatory Proteins><Health><Hormones><Human><Humulin R><Hyperglycemia><Immune><Immunes><Individual><Insulin><Insulin Cell><Insulin Secreting Cell><Intracellular Communication and Signaling><Intracellular Second Messenger><Islet Cell><Isoforms><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Life Style><Lifestyle><Link><Maturity-Onset Diabetes Mellitus><Mediating><Medication><Membrane><Metabolic><Methods><Mice><Mice Mammals><Modern Man><Molecular><Murine><Mus><NIDDM><Non obese><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nonobese><Novolin R><Null Mouse><Obesity><Organ Donor><Osmosis><PGE2><PGE2 alpha><PGE2alpha><Pancreas><Pancreatic><Pancreatic beta Cell><Pancreatic β-Cell><Pancreozymin><Paracrine Communication><Paracrine Signaling><Pathway interactions><Pharmaceutical Preparations><Physiopathology><Pre-Clinical Model><Pre-DM><Preclinical Models><Prediabetes><Prediabetes syndrome><Prediabetic State><Prevalence><Preventive><Process><Production><Prostaglandin E2><Prostaglandin E2 alpha><Prostaglandin E2alpha><Protein Isoforms><Public Health><Pump><RNA Splicing><Receptor Protein><Regular Insulin><Regulation><Research><Residual><Residual state><Resistance><Role><Second Messenger Systems><Second Messengers><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Slow-Onset Diabetes Mellitus><Splicing><Stable Diabetes Mellitus><Stimulus><Structure of beta Cell of islet><Subcellular Process><Sulfonylurea Compounds><T2 DM><T2D><T2DM><Testing><Therapeutic><Therapeutic Hormone><Tissue Growth><Tissues><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Uropancreozymin><Variant><Variation><Veterans><Work><adenosine 3'5' monophosphate><adiposity><adult onset diabetes><alpha-cell><antagonism><antagonist><autocrine><biological signal transduction><cAMP><causation><cell type><cellular targeting><chronic disorder><corpulence><cost><diabetes><diabetes mellitus therapy><diabetes risk><diabetes therapy><diabetic><diabetic patient><diabetogenic><disease causation><drug/agent><functional loss><gene expression pattern><gene expression signature><glucagon-like peptide 1><glucagon-like peptide-1 receptor><healthspan><healthy life span><hyperglycemic><improved><incretin hormone><innovate><innovation><innovative><insulin secretion><islet><ketosis resistant diabetes><kids><life-time risk><lifetime risk><maturity onset diabetes><membrane structure><metabolome><metabonome><military veteran><necrocytosis><non-diabetic><nondiabetic><novel><ontogeny><pancreas beta cell><pancreas β cell><pancreatic b-cell><paracrine><pathophysiology><pathway><patient population><pharmacologic><pre-diabetes><pre-diabetic><prediabetic><preservation><prevent><preventing><programs><receptor><resistant><signal transduction second messengers><social role><sulfonylurea><therapeutic target><transcriptional profile><transcriptional signature><type 2 DM><type II DM><type two diabetes><veteran population><youngster><α-cell><β-cell><β-cells><βCell>

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Kathryn Colbert Coate

VETERANS HEALTH ADMINISTRATION, NASHVILLE, TN

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

Pancreatic islet alpha cell response to insulin resistance and type 2 diabetes

Grant Number:

5IK2BX006210-03

Activity Code:

IK2

Mechanism:

Other

Agency:

VA

Start Date:

10/1/2023

End Date:

9/30/2026

Project Abstract

Type 2 diabetes (T2D) is a chronic disease that affects nearly 25% of U.S. Veterans, a prevalence that exceeds that among the civilian population, and represents a growing challenge to the VA healthcare system. T2D comprises a heterogeneous set of metabolic disorders that commonly arises from obesit...

Research Terms

<21+ years old><Acute><Address><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Alpha Cell><Antidiabetic Hormone><B9 endocrine pancreas><Basal Transcription Factor><Basal transcription factor genes><Basic Research><Basic Science><Beta Cell><Bioinformatics><Biology><Business-Friendly Atmosphere><Candidate Disease Gene><Candidate Gene><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cell Body><Cell Function><Cell Physiology><Cell Process><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular biology><Chromatin><Chronic><Chronic Disease><Chronic Illness><Coupled><D-Glucose><Developmental Biology><Dextrose><Diabetes Mellitus><Disease><Disorder><Down-Regulation><Dysfunction><Electron Microscopy><Endocrine Pancreas><Environment><Evaluation><Exocytosis><Expenditure><Exposure to><Expression Signature><Faculty Education><Faculty Training><Fats><Fatty acid glycerol esters><Foundations><Functional disorder><Gene Action Regulation><Gene Expression><Gene Expression Profile><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genetic><Genetic Transcription><Genetic study><Glucagon><Glucagon Cell><Glucagon Secreting Cell><Glucose><Glucose Intolerance><Glukagon><Grant><HG-Factor><Health><Health Care Systems><Heterograft><Heterologous Transplantation><High Fat Diet><Hormonal><Hormone secretion><Human><Humulin R><Hyperglycemia><Hyperglycemic-Glycogenolytic Factor><Immunocompromised><Immunocompromised Host><Immunocompromised Patient><Immunosuppressed Host><Impairment><In Vitro><In vivo analysis><Insulin><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><International><Investigators><Ion Channel><Ionic Channels><Islands of Langerhans><Islands of Langerhans Transplantation><Islands of Pancreas Transplantation><Islet Cell><Islets of Langerhans><Islets of Langerhans Grafting><Islets of Langerhans Transplantation><K-Awards><K-Series Research Career Programs><KO mice><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Knowledge><Lead><Link><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Membrane Channels><Mentors><Mentorship><Metabolic><Metabolic Diseases><Metabolic Disorder><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Murine><Mus><NIDDM><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Novolin R><Nuclear><Null Mouse><Obesity><Oxidative Stress><Pancreatic Diseases><Pancreatic Disorder><Pancreatic Islets><Pancreatic Islets Transplantation><Pancreatic Secretion><Pars endocrina pancreatis><Pathologic><Pathology><Pattern><Pb element><Physiologic><Physiological><Physiopathology><Population><Prevalence><Production><Publishing><RNA Expression><Regular Insulin><Research><Research Career 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View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Peter D Reaven

PHOENIX VA HEALTH CARE SYSTEM, PHOENIX, AZ

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

Use of continuous glucose monitoring and long-term diabetes outcomes within the Veteran Affairs Health Care System

Grant Number:

5I01BX006126-03

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

10/1/2023

End Date:

9/30/2027

Project Abstract

Summary: Continuous glucose monitoring (CGM) is increasing rapidly in the Veterans Administration Health Care System (VAHCS). Experience with CGM is greatly modifying our concepts of glucose control and our understanding of how to define and achieve optimal glucose goals. Most available data on CGM ...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Andrew T. Templin

RLR VA MEDICAL CENTER, INDIANAPOLIS, IN

Exploratory lead · 10/100

Active award

$0

FY 2026

Project Title

Novel roles for RIP kinases in islet inflammation and beta-cell cytotoxicity in type 2 diabetes

Grant Number:

5I01BX006913-02

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

10/1/2024

End Date:

9/30/2028

Project Abstract

Background and Innovation: β-cell failure is a hallmark of type 2 diabetes (T2D) that arises with islet amyloid formation, islet inflammation, β-cell loss and hyperglycemia. However, the cellular and molecular mechanisms that underlie this pathogenic process are not well understood. Receptor interac...

Research Terms

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Ann Marie Borzecki

EDITH NOURSE ROGERS MEMORIAL VETERANS HOSPITAL, BEDFORD, MA

Exploratory lead · 6/100

$0

FY 2026

Project Title

Prediction and Prevention of Hypoglycemia in Veterans with Diabetes

Grant Number:

5I01HX002355-07

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

8/1/2019

End Date:

4/30/2025

Project Abstract

Control of hyperglycemia to prevent or delay the onset of vascular complications is a fundamental goal of diabetes care. Intensive treatment is limited, however, by risk of hypoglycemia, a common and potentially hazardous metabolic complication of glucose-lowering treatment. Traditionally, this risk...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

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