Nuo Sun

OHIO STATE UNIVERSITY, Columbus, OH

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$587,483

FY 2026

Project Title

Neddylation and mitophagy in cardiac aging

Grant Number:

5R01HL162909-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2022

End Date:

3/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY A decline in mitochondrial quality and activity has been associated with normal aging and correlated with the development of a wide range of age-related diseases. Therefore, rejuvenating mitochondrial function or improving mitochondrial quality control might be an effective strategy...

Research Terms

<21+ years old><APF-1><ATP-Dependent Proteolysis Factor 1><Adult><Adult Human><Adverse effects><Age><Aging><Algorithm Design><Algorithmic Design><Algorithmic Engineering><Algorithms><Assay><Autoregulation><BCL2-Interacting Protein><Binding Proteins><Bioassay><Biological Assay><Cardiac><Cardiac Muscle Cells><Cardiac Myocytes><Cardiocyte><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular Physiology><Cardiovascular system><Cell Culture Techniques><Collection><Complex><Cullin 2><Cullin 2 Protein><DNA Therapy><DP5><Data><Development><Drug Therapy><E3 Ligase><E3 Ubiquitin Ligase><Elderly><Enzyme Gene><Enzymes><Gene Transfer Clinical><Genetic><Genetic Intervention><Goals><HIF 1><HIF-1 protein><HIF1><HIF1 protein><HMG-20><HRK gene><Harakiri><Heart><Heart Muscle Cells><Heart Muscle tissue><Heart Vascular><Heart failure><Heart myocyte><High Mobility Protein 20><Homeostasis><Human><Image><Increase lifespan><Ligand Binding Protein><Ligand Binding Protein Gene><Link><Mediating><Mice><Mice Mammals><Mitochondria><Modern Man><Molecular><Murine><Mus><Myocardial depression><Myocardial dysfunction><Myocardial tissue><Pathologic><Pathology><Pathway interactions><Patients><Pharmacological Treatment><Pharmacotherapy><Physiologic><Physiological><Physiological Homeostasis><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Protein Binding><Protein Modification><Proteins><Quality Control><RBX1><RBX1 gene><RING-Box 1><ROC1><Reagent><Receptor Protein><Regulation><Regulator of Cullins 1><Reporter><Research><Role><Scaffolding Protein><Therapeutic><Tissue Sample><Ubiquitilation><Ubiquitin><Ubiquitin Like Proteins><Ubiquitin Protein Ligase><Ubiquitin-Protein Ligase Complexes><Ubiquitin-Protein Ligase E3><Ubiquitination><Ubiquitinoylation><VHL gene product><VHL protein><abrogation of mitochondrial dysfunction><adult youth><adulthood><advanced age><age associated><age associated cardiac dysfunction><age associated decline><age associated disease><age associated disorder><age associated effects><age associated heart dysfunction><age associated impairment><age correlated><age dependent><age dependent decline><age dependent disease><age dependent disorder><age dependent impairment><age effect><age induced cardiac dysfunction><age linked><age related><age related cardiac dysfunction><age related decline><age related effects><age related heart dysfunction><age related human disease><age reversal><age specific><age-related disease><age-related disorder><age-related impairment><aged><aged mice><aged mouse><ages><aging associated><aging effect><aging related><aging reversal><algorithm engineering><algorithmic composition><alleviate age related><alleviate aging><alleviating mitochondrial dysfunction><ameliorating aging><ameliorating mitochondrial dysfunction><attenuation of mitochondrial dysfunction><boost longevity><bound protein><cardiac aging><cardiac dysfunction><cardiac failure><cardiac function><cardiac myocytes differentiated from induced pluripotent stem cell><cardiomyocyte><cardioprotectant><cardioprotection><cardioprotective><cardiovascular function><cardiovascular health><cell culture><cell cultures><circulatory system><combat><counter age related><counter aging><counteract age related><counteract aging><decline with age><developmental><disease risk><disorder risk><drug intervention><drug treatment><elderly mice><elongating the lifespan><elongin B><enhance longevity><extend life span><extend lifespan><extend longevity><foster longevity><function of the heart><gene repair therapy><gene therapy><gene-based therapy><genetic therapy><genomic therapy><geriatric><heart aging><heart dysfunction><heart function><hiPSC><human iPS><human iPSC><human induced pluripotent cell><human induced pluripotent stem cells><human inducible pluripotent stem cells><human inducible stem cells><hypoxia inducible factor 1><iPS cell derived cardiomyocytes><iPSC derived cardiomyocytes><imaging><impact of age><improve lifespan><improve longevity><improved><in vivo monitoring><induced human pluripotent stem cells><induced pluripotent stem cell derived cardiac myocytes><induced pluripotent stem cell derived cardiomyocytes><inducible pluripotent stem cell derived cardiac myocytes><inducible pluripotent stem cells derived cardiomyocytes><influence of age><inhibitor><innovate><innovation><innovative><insight><lifespan extension><mitigating mitochondrial impairment><mitochondrial><mitochondrial rejuvenation><model organism><mortality><mouse model><murine model><natural aging><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><normal aging><normative aging><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><old mice><pathway><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><preservation><prevent><preventing><prolong lifespan><prolong longevity><promote lifespan><promote longevity><receptor><reducing mitochondrial dysfunction><reverse age><reverse aging><reverse aging effects><reversible aging><senior citizen><social role><spatial and temporal><spatial temporal><spatiotemporal><support longevity><suppress mitochondrial dysfunction><therapeutic target><ubiquination><ubiquitin conjugation><ubiquitin-protein ligase><von Hippel Lindau disease gene product><von Hippel Lindau disease protein><von Hippel Lindau gene product><von Hippel Lindau protein><young adult><young adult age><young adulthood>

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Anyonya R Guntur

MAINEHEALTH, PORTLAND, ME

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$562,524

FY 2026

Project Title

Mitochondrial function regulates ROS-mediated patterning following injury

Grant Number:

5R01HD112474-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Mitochondria are critical for generating energy. Recently a new role for mitochondria in controlling metabolic signaling through generation of reactive oxygen species (ROS) has come to light. ROS has also recently come into the spotlight as being a critical signaling axis for limb regenerat...

Research Terms

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Mimi C Sammarco

MAINEHEALTH, PORTLAND, ME

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$562,524

FY 2026

Project Title

Mitochondrial function regulates ROS-mediated patterning following injury

Grant Number:

5R01HD112474-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Mitochondria are critical for generating energy. Recently a new role for mitochondria in controlling metabolic signaling through generation of reactive oxygen species (ROS) has come to light. ROS has also recently come into the spotlight as being a critical signaling axis for limb regenerat...

Research Terms

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Robert Tower

MAINEHEALTH, PORTLAND, ME

Good lead · 66/100

Likely hiring

Above-average budget

Recent

Active award

$562,524

FY 2026

Project Title

Mitochondrial function regulates ROS-mediated patterning following injury

Grant Number:

5R01HD112474-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2024

End Date:

2/28/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Abstract Mitochondria are critical for generating energy. Recently a new role for mitochondria in controlling metabolic signaling through generation of reactive oxygen species (ROS) has come to light. ROS has also recently come into the spotlight as being a critical signaling axis for limb regenerat...

Research Terms

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KRISHNA MOORTHI BHAT

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

Good lead · 66/100

Likely hiring

Solid budget

Very recent

Active award

$469,350

FY 2026

Project Title

Functional role of Sec20, a BH3 and Secretory (Sec) domain protein, in neurons and its relevance to a motor neuron disease in Drosophila

Grant Number:

4R01NS131315-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2023

End Date:

3/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

This proposal examines the functional role of Sec20, a BH3 and Secretory (Sec) domain protein, in neurons and its relevance to a motor neuron disease using Drosophila. It also examines the interaction between sec20 and GGGGCC (G4C2) repeats of the gene C9orf72 (Chromosome9 open reading frame), a wel...

Research Terms

<21+ years old><Adenoviridae><Adenoviruses><Adult><Adult Human><Affect><Amentia><Amyotrophic Lateral Sclerosis><Amyotrophic Lateral Sclerosis Motor Neuron Disease><Amyotrophic lateral sclerosis and frontotemporal degeneration><Amyotrophic lateral sclerosis and frontotemporal dementia><Apoptosis><Apoptosis Pathway><Apoptotic><Autophagocytosis><Autophagosome><B-Cell CLL/Lymphoma 2 Gene><B-cell lymphoma/leukemia-2><BCL2><BCL2 gene><BCL2-Interacting Protein><Bcl-2><Bioenergetics><Biologic Models><Biological Models><Biology><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><C9ORF72><Cell Death><Cessation of life><Chromosomes><Citrate (si)-Synthase><Citrate Synthase><Collaborations><DNA Molecular Biology><DNA mutation><DP5><Data><Death><Defect><Degenerative Neurologic Disorders><Dementia><Development><Disease><Disorder><Drosophila><Drosophila genus><Encephalon><Encephalon Diseases><Erythrocuprein><Eye><Eyeball><FTD dementia><FTD/ALS><FTLD/ALS><Failure><Female><Flies><Frontal Temporal Dementia><Frontotemporal Dementia><Frontotemporal Lobar Degeneration/Amyotrophic lateral sclerosis><GWA study><GWAS><Gehrig's Disease><Genes><Genetic><Genetic Change><Genetic Models><Genetic defect><Genetic mutation><Glutamates><Goals><HRK gene><Harakiri><Health><Hemocuprein><Human><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Knowledge><L-Glutamate><Link><Lou Gehrig Disease><Lysosomes><Mediating><Mission><Mitochondria><Model System><Modern Man><Molecular><Molecular Biology><Motor Cell><Motor Neuron Disease><Motor Neurons><Movement><Mutation><NIH><National Institutes of Health><Nerve Cells><Nerve Unit><Nervous System><Nervous System Degenerative Diseases><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurobiology><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Body System><Neurologic Degenerative Conditions><Neurologic Disorders><Neurologic Organ System><Neurological Disorders><Neurology><Neurons><ORFs><Open Reading Frames><Ortholog><Orthologous Gene><Pathology><Patients><Peptide Domain><Phenotype><Play><Programmed Cell Death><Protein Coding Region><Protein Domains><Protein Family><Proteins><Public Health><Publishing><Reporting><Risk Factors><Role><Sampling><Superoxide Dismutase><System><Techniques><Tertiary Protein Structure><United States National Institutes of Health><Work><adulthood><amyotrophic lateral sclerosis with frontotemporal dementia><amyotrophic lateral sclerosis/FTLD><amyotrophic lateral sclerosis/frontotemporal dementia><amyotrophic lateral sclerosis/ftd><apoptosis of neuronal cells><autophagy><bcl-2 Genes><body movement><ced9 homolog><cell transformation><chromosome 9 open reading frame 72><cytocuprein><degenerative diseases of motor and sensory neurons><degenerative disorder of motor neurons><degenerative neurological diseases><developmental><fly><front temporal dementia><frontal lobe dementia><frontotemporal dementia-amyotrophic lateral sclerosis><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobar dementia amyotrophic lateral sclerosis><frontotemporal lobe degeneration associated with dementia><fruit fly><gene function><genome mutation><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><glutamatergic><insight><knock-down><knockdown><loss of function><male><member><mitochondrial><mitochondrial dysfunction><motoneuron><motor deficit><motor disease><motor disorder><motor dysfunction><motor neuron function><mouse model><murine model><mutant><necrocytosis><nerve cell death><nerve cell loss><neurobiological><neurodegenerative illness><neurological disease><neuron apoptosis><neuron cell death><neuron cell loss><neuron death><neuron loss><neuronal><neuronal apoptosis><neuronal cell death><neuronal cell loss><neuronal cells programmed cell death><neuronal death><neuronal loss><neuronal survival><neurons programmed cell death><prevent><preventing><pro-apoptotic protein><programmed cell death of neuronal cells by apoptosis><programmed cell death of neurons by apoptosis><recruit><social role><tool><transformed cells><whole genome association analysis><whole genome association study><♀><♂>

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David W Walker

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 60/100

Likely hiring

Above-average budget

Active award

$554,549

FY 2026

Project Title

Role of Mitochondrial Homeostasis in Animal Aging

Grant Number:

5R01AG037514-14

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2010

End Date:

12/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project Summary As advanced age is the most significant risk factor for Alzheimer’s disease (AD), targeting detrimental age-related processes may lead to effective therapies. Mitochondrial dysfunction and pro-inflammatory signaling are each thought to be key drivers of aging and AD. However, a clear...

Research Terms

<21+ years old><AD and related dementia><AD brain><AD dementia><AD model><AD pathology><AD patients><AD related dementia><AD risk><AD risk factor><ADRD><Acids><Adult><Adult Human><Age of Onset><Aging><Agonist><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's Disease and its related dementias><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease and related forms of dementia><Alzheimer's disease brain><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's pathology><Alzheimer's patient><Alzheimers Dementia><Animals><Autophagocytosis><Autoregulation><BCL2-Interacting Protein><Binding Proteins><Biological><Body System><Body Tissues><Brain><Brain Nervous System><Cell Communication and Signaling><Cell Signaling><Cell model><Cellular model><Cytosol><DNA><DNA Nucleases><DNase><DP5><Deoxyribonucleases><Deoxyribonucleic Acid><Development><Drosophila><Drosophila genus><Elderly><Encephalon><Flies><Genetic><Goals><HRK gene><Harakiri><Health><Homeostasis><Immune Cell Activation><Immune signaling><Immune system><Immunoglobulin Enhancer-Binding Protein><Increase lifespan><Inflammation><Inflammatory><Inflammatory Response><Innate Immune Response><Innate Immune System><Intracellular Communication and Signaling><Knowledge><Ligand Binding Protein><Ligand Binding Protein Gene><Link><Lysosomes><Mammalia><Mammals><Mediating><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Mitochondria><Mitochondrial DNA><Molecular><NF-kB><NF-kappa B><NF-kappaB><NFKB><Nerve Cells><Nerve Unit><Nervous System><Neural Cell><Neurocyte><Neurologic Body System><Neurologic Organ System><Neurons><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Onset of illness><Organ System><Outer Mitochondrial Membrane><Pathogen detection><Pathogenesis><Pathology><Physiological Homeostasis><Prevalence><Primary Senile Degenerative Dementia><Process><Protein Binding><Reporting><Research><Research Design><Respiratory Chain><Risk Factors><Role><Signal Transduction><Signal Transduction Systems><Signaling><Stress><Study Type><Surface Proteins><System><Therapeutic Intervention><Tissues><Transcription Factor NF-kB><Upregulation><Work><adulthood><advanced age><age associated><age associated disease><age associated disorder><age associated impairment><age correlated><age dependent><age dependent disease><age dependent disorder><age dependent impairment><age linked><age related><age related human disease><age related pathways><age reversal><age specific><age-related disease><age-related disorder><age-related impairment><aged><aged brain><aging associated><aging associated mechanism><aging brain><aging mechanism><aging pathway><aging related><aging related mechanism><aging related pathways><aging reversal><alleviate age related><alleviate aging><alzheimer model><alzheimer risk><ameliorating aging><autophagy><biologic><biological mechanism of age><biological pathways of age><biological signal transduction><boost longevity><bound protein><counter age related><counter aging><counteract age related><counteract aging><developmental><disease onset><disorder onset><drivers of aging><effective therapy><effective treatment><elongating the lifespan><enhance longevity><extend life span><extend lifespan><extend longevity><fly><foster longevity><fruit fly><genetic approach><genetic strategy><geriatric><gerodriver><hallmarks of aging><healthspan><healthy life span><immune activation><improve lifespan><improve longevity><intervention therapy><kappa B Enhancer Binding Protein><lifespan extension><mechanism regulating aging><mechanisms involved in aging><mitochondrial><mitochondrial autophagy><mitochondrial dysfunction><mtDNA><neural inflammation><neuroinflammation><neuroinflammatory><neuronal><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutic target><new therapeutics><new therapy><new therapy approaches><new therapy target><new treatment approach><new treatment strategy><next generation therapeutics><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutic target><novel therapeutics><novel therapy><novel therapy approach><novel therapy target><nuclear factor kappa beta><pathway involved in aging><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><patients with AD><pillars of aging><prevent><preventing><primary degenerative dementia><prolong lifespan><prolong longevity><promote lifespan><promote longevity><reverse age><reverse aging><reverse aging effects><reversible aging><risk factor for developing Alzheimer's><risk factor in Alzheimer's><risk of developing Alzheimer's><senile dementia of the Alzheimer type><senior citizen><sensor><social role><study design><support longevity><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment>

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Corina Amor Vegas

COLD SPRING HARBOR LABORATORY, COLD SPRING HARBOR, NY

Good lead · 54/100

Likely hiring

Above-average budget

Active award

$960,000

FY 2025

Project Title

Deconstructing aging with senolytic CAR T cells

Grant Number:

4DP5OD033055-04

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2022

End Date:

8/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

SUMMARY Gaining a better understanding of aging biology is a pressing health and socioeconomic issue. In this regard, cellular senescence is a key, but poorly understood determinant of organismal aging. Senescence is a stress response program characterized by stable cell cycle arrest. Initially desc...

Research Terms

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Mary D Willis

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 54/100

Likely hiring

Above-average budget

Active award

$825,000

FY 2025

Project Title

A Preconception Cohort Study on Oil and Gas Development, Fertility, and Pregnancy

Grant Number:

4DP5OD033415-04

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2022

End Date:

8/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Over 17.6 million North Americans live within 1.6km of an oil and gas development (OGD) facility. Recent studies indicate that OGD results in the release of reproductive toxicants (e.g., particulate matter, volatile organic compounds [VOCs], polycyclic aromatic hydrocarbons [PAHs]) a...

Research Terms

<0-11 years old><Active Follow-up><Address><Affect><Air><American><Aromatic Polycyclic Hydrocarbons><Award><BCL2-Interacting Protein><Back><Benzene><Benzol><Benzole><Birth><Boston><Canada><Chemicals><Child><Child Development><Child Health><Child Youth><Children (0-21)><Cohort Studies><Communities><Complex><Conceptions><Concurrent Studies><Contracting Opportunities><Contracts><Couples><Cyclohexatriene><DP5><Data><Data Analyses><Data Analysis><Data Collection><Data Science><Development><Diet><Disease><Disorder><Dorsum><Drugs><EPH Gestosis><Enrollment><Environmental Epidemiology><Environmental Hazards><Environmental Pollutants><Epidemiologic Research><Epidemiologic Studies><Epidemiologic analysis><Epidemiological Studies><Epidemiology><Epidemiology Research><Exposure to><Faculty><Fecundability><Fecundity><Fellowship><Female><Fertility><Flare><Formaldehyde><Formic Aldehyde><Funding><Gases><Geography><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Gestational Hypertension><Grant><HRK gene><Harakiri><Health><History><Human><Hydrogen Oxide><Hypertension><Hypertension induced by pregnancy><Industry><Infant and Child Development><Institution><Interdisciplinary Research><Interdisciplinary Study><Internet><Investigators><Job Location><Job Place><Job Setting><Job Site><Late pregnancy><Life Style><Lifestyle><Light><Live Birth><Low Birth Weight Infant><Measurement><Measures><Medical History><Medication><Menstrual cycle><Mentors><Metabolic Diseases><Metabolic Disorder><Methods><Methyl Aldehyde><Miscarriage><Modern Man><Multidisciplinary Collaboration><Multidisciplinary Research><NICHD><NIEHS><NIH><National Institute of Child Health and Human Development><National Institute of Environmental Health Sciences><National Institutes of Health><Noise><Oils><Outcome><Oxomethane><Participant><Particulate Matter><Parturition><Personal Medical History><Personal Medical History Epidemiology><Pharmaceutical Preparations><Photoradiation><Play><Policies><Pollution><Position><Positioning Attribute><Post-partum Women><Postdoc><Postdoctoral Fellow><Postpartum Women><Pre-Eclampsia><Preeclampsia><Pregnancy><Pregnancy Associated Hypertension><Pregnancy Toxemias><Pregnancy loss><Pregnancy-Induced Diabetes><Premature Birth><Prematurely delivering><Preterm Birth><Probability><Production><Prospective cohort><Prospective, cohort study><Proteinuria-Edema-Hypertension Gestosis><Province><Public Health><Public Health Schools><Questionnaires><Recording of previous events><Reporting><Reproductive Health><Research><Research Associate><Research Design><Research Personnel><Research Resources><Researchers><Resources><Risk><Role><Spontaneous abortion><Study Type><Survey Instrument><Surveys><TL1><TNF Ligand-Related Molecule 1><TNF15><TNFSF15><TNFSF15 gene><Techniques><Thesaurismosis><Time><Toluene><Toxicology><Training><Tumor Necrosis Factor Ligand Superfamily Member 15><United States><United States National Institutes of Health><Universities><VEGI><Vascular Endothelial Growth Inhibitor><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><WWW><Water><Woman><Work><Work Location><Work Place><Work-Site><Workplace><Worksite><active followup><before conception><career><cohort><community intervention><community level intervention><community-based intervention><cost effective><data integration><data interpretation><design><designing><developmental><diets><drug/agent><early in pregnancy><early pregnancies><early pregnancy><early pregnancy loss><early stage of pregnancy><enroll><environmental contaminant><epidemiologic><epidemiologic evaluation><epidemiologic investigation><epidemiological><epidemiology study><follow up><follow-up><followed up><followup><high blood pressure><histories><hyperpiesia><hyperpiesis><hypertension during pregnancy><hypertension in pregnancy><hypertensive disease><hypertensive disorder><hypertensive pregnancy><improved><kids><low birth weight><low birthweight><metabolism disorder><methyl-benzene><novel><participant enrollment><patient enrollment><pollutant><polyaromatic hydrocarbons><polynuclear aromatic hydrocarbon><population health><post-doc><post-doctoral><post-doctoral trainee><postpartum health><pre-doc><pre-doctoral><pre-eclamptic><preconception><pregnancy characterized by hypertension><pregnancy diabetes><pregnancy hypertension><pregnancy toxemia/hypertension><pregnancy-related hypertension><premature childbirth><premature delivery><preterm delivery><prior to conception><professor><prospective><recruit><reproductive><research associates><risk perception><social role><social stresses><social stressor><socio-demographics><sociodemographics><study design><time-to-pregnancy><toxicant><trying to conceive><volatile organic chemical><volatile organic compound><web><work setting><world wide web><youngster><♀>

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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lisa Hiura

UNIVERSITY OF COLORADO, Boulder, CO

Good lead · 54/100

Likely hiring

Above-average budget

Active award

$782,500

FY 2025

Project Title

Functional ontogeny of pair bonding neural circuits

Grant Number:

4DP5OD033437-04

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/13/2022

End Date:

8/31/2027

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.
• Award size is strong enough to merit immediate review.

Project Abstract

Project summary/Abstract The rewarding bonds we forge in adulthood, in particular our pair bonds with romantic partners, have innumerable protective effects on our brains and behaviors. Individuals with difficulties in social engagement and competence, such as those suffering from social anxiety, ma...

Research Terms

<12-20 years old><21+ years old><AD/HD><ADHD><ASD><Adolescence><Adolescent><Adolescent Development><Adolescent Youth><Adult><Adult Human><Age><Agreement><Animal Care Assistants><Animal Care Technicians><Animal Technicians><Animals><Appointment><Attention deficit hyperactivity disorder><Autism><Autistic Disorder><Automobile Driving><Award><BCL2-Interacting Protein><Basic Research><Basic Science><Behavior><Behavior Control><Behavioral Manipulation><Behavioral Paradigm><Brain><Brain Nervous System><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cellular Function><Cellular Physiology><Cellular Process><Cellular biology><Color><Colorado><Common Rat Strains><Core Facility><DNA Molecular Biology><DP5><Development><Developmental Biology><Disease><Disorder><Dopamine><Dryness><Dysfunction><Early Infantile Autism><Embryo Development><Embryogenesis><Embryonic Development><Emotional well being><Encephalon><Ensure><Expression Signature><Faculty><Feels well><Fellowship><Female><Fiber><Foundations><Functional disorder><Funding><Gene Action Regulation><Gene Expression Profile><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Gene Transcription><Generalized Growth><Genetic><Genetic Transcription><Goals><Grant><Growth><HRK gene><Harakiri><Health><Health Benefit><History><Home><Hydroxytyramine><Imaging Procedures><Imaging Technics><Imaging Techniques><Impairment><Impoverished><Individual><Infantile Autism><Institution><Intracellular Communication and Signaling><Kanner's Syndrome><Knowledge><Laboratories><Laboratory Rat><Laboratory mice><Life><Major Depressive Disorder><Mediating><Mentors><Mentorship><Microscopy><Microtus><Molecular><Molecular Biology><Motivation><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurodevelopmental Disorder><Neurological Development Disorder><Neurons><Neurosciences><Normal mental condition><Normal mental state><Normal psyche><Pair Bond><Partner in relationship><Pathogenesis><Pathology><Pharmacogenetics><Phenotype><Photometry><Physiologic><Physiological><Physiopathology><Play><Position><Positioning Attribute><Poverty><Predisposition><Predominantly Hyperactive-Impulsive Type Attention-Deficit Disorder><Predominantly Hyperactive-Impulsive Type Hyperactivity Disorder><Principal Investigator><Process><Property><Psychological Well Being><Publications><RNA Expression><Rat><Rats Mammals><Rattus><Recording of previous events><Research><Research Assistant><Research Resources><Resources><Rewards><Risk><Rodent><Rodent Model><Rodentia><Rodents Mammals><Role><Same-sex><Schizophrenia><Schizophrenic Disorders><Scientific Publication><Secure><Sense of well-being><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Social Behavior><Social Development><Social Interaction><Social Network><Social Support System><Social isolation><Stem Cell Research><Subcellular Process><Support System><Susceptibility><System><Technical Expertise><Technology><Therapeutic><Time><Tissue Growth><Transcription><Translational Research><Translational Science><Universities><Veterinary Assistants><Veterinary Nurses><Veterinary Technicians><Viral><Vole><Well in self><Work><adolescence (12-20)><adult animal><adulthood><ages><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><behavioral control><biological signal transduction><career><cell biology><clinical depression><data analysis pipeline><data processing pipeline><deficits in reward learning><dementia praecox><design><designing><developmental><dopamine system><driving><emotional wellbeing><emotional wellness><experience><field mouse><forging><functional outcomes><gene expression pattern><gene expression signature><genetic approach><genetic strategy><histories><homes><human model><in vivo><innovate><innovation><innovative><insight><instrumentation><interest><interpersonal competence><interpersonal competency><juvenile><juvenile human><loved ones><major depression><major depression disorder><mate><mature animal><mental well-being><mental wellbeing><mental wellness><mesolimbic dopamine system><mesolimbic system><model of human><neural><neural circuit><neural circuitry><neural control><neural mechanism><neural regulation><neurocircuitry><neurodevelopmental disease><neuromechanism><neuromodulation><neuromodulatory><neuronal><neuropsychiatric><neuropsychiatric disease><neuropsychiatric disorder><neuropsychiatry><neuroregulation><novel><ontogeny><optogenetics><pathophysiology><post-natal development><postnatal development><prairie vole><professor><programs><protective effect><psychological wellbeing><psychological wellness><reward circuit dysfunction><reward circuitry><reward dysfunction><reward system dysfunction><scaffold><scaffolding><schizophrenic><self wellness><sense of wellbeing><sex><social><social anxiety><social attachment><social bonding><social competence><social competency><social defects><social deficits><social disorders><social dysfunction><social engagement><social involvement><social neuroscience><social participation><social role><social skills><socially anxious><sociobehavior><sociobehavioral><stem cell study><synaptic circuit><synaptic circuitry><technical skills><therapeutic target><transcriptional profile><transcriptional signature><translation research><translational investigation><♀>

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Jacob Andreas Zavatone-Veth

HARVARD UNIVERSITY, CAMBRIDGE, MA

Good lead · 46/100

Likely hiring

Solid budget

Active award

$422,500

FY 2025

Project Title

Understanding data-driven models for neural dynamics

Grant Number:

5DP5OD037354-02

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2024

End Date:

7/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract Recent technical advances have enabled to record the activity of hundreds or thousands of neurons simulta- neously. To extract insight from this deluge of data, computational neuroscientists have turned to data-driven modeling approaches. In this paradigm, an artificial recu...

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Grant Jones

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 46/100

Likely hiring

Solid budget

Active award

$412,500

FY 2025

Project Title

Examining the effects of naturalistic hallucinogen use on internalizing symptoms in a longitudinal sample of young adults

Grant Number:

1DP5OD039401-01

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/6/2025

End Date:

7/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Hallucinogens are a heterogeneous group of substances that cause visual and auditory hallucinations, profound changes in one’s perception of time and space, and changes in mood. Many hallucinogens are also referred to as psychedelics. In recent years, there has been a massive resurgence of interest ...

Research Terms

<3,4 methylenedioxymethamphetamine><Address><Adverse effects><Affect><Age><American><Anxiety><Area><Auditory Hallucination><BCL2-Interacting Protein><Causality><Characteristics><Clinical><Clinical Research><Clinical Study><Clinical Trials><Cross Sectional Analysis><Cross-Sectional Analyses><Cross-Sectional Studies><Cross-Sectional Survey><DP5><Data><Dedications><Department chair><Disease><Disease Frequency Surveys><Disorder><Dose><Economic Income><Economical Income><Education><Educational aspects><Emotional Depression><Emotional well being><Ensure><Etiology><Feels well><Foundations><Funding><Future><General Hospitals><Goals><Government><HRK gene><Hallucinogenic Agents><Hallucinogenic Drugs><Hallucinogenic Substances><Hallucinogens><Harakiri><Health><Income><Individual><Institution><Interdisciplinary Research><Interdisciplinary Study><Investigation><Investigators><Journals><Ketamine><Knowledge><Light><Link><Loneliness><Longitudinal Studies><MDMA><Machine Learning><Magazine><Manuscripts><Marital Status><Massachusetts><Medical><Meditation><Mental Depression><Mental disorders><Mental health disorders><Mentors><Mentorship><Methods><Methylenedioxymethamphetamine><Modeling><Monitor><Moods><Multidisciplinary Collaboration><Multidisciplinary Research><Music><N,alpha-dimethyl-1,3-benzodioxole-5-ethanamine><N-Methyl-3,4-methylenedioxyamphetamine><NIH><National Institutes of Health><Neurosciences><Normal mental condition><Normal mental state><Normal psyche><Observation research><Observation study><Observational Study><Observational research><Outcome><Paranoia><Paranoid Disorders><Personal Satisfaction><Persons><Photoradiation><Position><Positioning Attribute><Probability><Psyche structure><Psychedelic Agents><Psychedelics><Psychiatric Disease><Psychiatric Disorder><Psychiatry><Psychological Well Being><Psychotherapy><Psychotomimetic Agents><Public Health><Public Policy><Publishing><Randomization trial><Randomized, Controlled Trials><Religion><Reporting><Research><Research Assistant><Research Personnel><Research Resources><Researchers><Resources><Robin><Robin bird><Sample Size><Sampling><Schedule><Schools><Secure><Sense of well-being><Spirituality><Structural Models><Symptoms><Techniques><Testing><Therapeutic Effect><Time><Time Perception><United States National Institutes of Health><Visual Hallucination><Well in self><Work><World Health><Youth><Youth 10-21><abuse liability><abuse potential><adult youth><age group><ages><career><causation><depression><depression symptom><depressive><depressive symptoms><design><designing><disease causation><ecstasy><emotional wellbeing><emotional wellness><experience><faculty mentor><improved><incomes><innovate><innovation><innovative><insight><interest><lonely><long-term study><longitudinal outcome studies><machine based learning><mental><mental illness><mental well-being><mental wellbeing><mental wellness><news><psychedelic drug><psychiatric illness><psychologic><psychological><psychological disorder><psychological wellbeing><psychological wellness><psychotomimetic drug><randomized control trial><randomized trial><religious><rurality><self esteem><self wellness><sense of wellbeing><substance use><substance using><tool><unethical><virtual><volunteer><well-being><wellbeing><young adult><young adult age><young adulthood><youth age>

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Julia Craig Bond

BOSTON UNIVERSITY MEDICAL CAMPUS, BOSTON, MA

Good lead · 46/100

Likely hiring

Solid budget

Active award

$408,750

FY 2025

Project Title

Female Sexual Dysfunction and Distress in the Preconception and Perinatal Period

Grant Number:

1DP5OD039736-01

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/11/2025

End Date:

7/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Female sexual dysfunction, defined as distressing impairments in sexual function, affects up to 40% of premenopausal women and represents a major public health problem. Despite its prevalence, the etiology is incompletely characterized. Knowledge gaps about sexual dysfunction are exa...

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Leo Le Wang

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 46/100

Likely hiring

Solid budget

Active award

$406,250

FY 2025

Project Title

Multicomponent hydrogels activating wound-induced hair neogenesis for scarless wound healing.

Grant Number:

1DP5OD039379-01

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/6/2025

End Date:

7/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Proposal Summary/Abstract Candidate: Dr. Leo Wang holds a BA, MS, MD, and PhD from the University of Pennsylvania, where he completed dermatology residency and currently is a Clinical Instructor and postdoctoral fellow working with Dr. George Cotsarelis in the Department of Dermatology. In 2025, Dr....

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Natasha Diba Sheybani

UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

Good lead · 46/100

Likely hiring

Solid budget

Active award

$395,430

FY 2025

Project Title

Immunoengineering Next-Generation Cancer Therapies with Focused Ultrasound

Grant Number:

5DP5OD031846-05

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/14/2021

End Date:

8/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Abstract Metastatic breast cancer (BrCa) is the 2nd most prevalent cause of cancer mortality in women in the United States, with a 5-year overall survival of only 22%. Though cancer immunotherapies are capable of generating durable responses across a variety of cancer types, immunologic reje...

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Leonid Shmuylovich

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 46/100

Likely hiring

Solid budget

Active award

$393,750

FY 2025

Project Title

Infrared Skin Imaging to Transform Noninvasive Diagnosis and Management of Skin Disease

Grant Number:

5DP5OD031872-05

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/14/2021

End Date:

8/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract Skin disease affects 1 in 4 Americans and costs $75 billion annually. Diagnosis relies upon visual inspection, but the subjective nature of visual assessment can lead to death from skin cancer misdiagnosis or suffering from misdiagnosis of a treatable chronic inflammatory co...

Research Terms

<0-11 years old><21+ years old><Address><Adult><Adult Human><Affect><American><Appearance><Appointment><Armpit><Award><Axilla><Axillary><BCL2-Interacting Protein><Benign><Biopsy><Body Tissues><Boils><Cessation of life><Child><Child Youth><Children (0-21)><Chronic><Cicatrix><Clinical><Communities><Coupled><Cutaneous><Cutaneous Disorder><Cutaneous imaging><DP5><Data><Death><Dedications><Dermatologic biopsy><Dermatological Imaging><Dermatologist><Dermatology><Dermatoses><Devices><Diagnosis><Diagnostic><Disease><Disease Marker><Disease Progression><Disorder><Disparities><Disparity><Engineering><Ensure><Epidermis><Exclusion><Extremities><Face><Furuncles><Future><General Radiology><Grant><Groin><HRK gene><Harakiri><Hemoglobin><Hidradenitis Suppurativa><Histologic><Histologically><Histology><Human><Hydrogen Oxide><Image><Imaging technology><Inflammation><Inflammatory><Inguinal region><Institution><Investigators><Joints><Lead><Leadership><Length><Lesion><Light><Limb structure><Limbs><Lipids><Malignant><Malignant - descriptor><Malignant Skin Neoplasm><Measures><Medicine><Melanins><Mentors><Methods><Microscopic><Modality><Modern Man><Nature><Neoplasms><Neoplastic skin><Non-Trunk><Optics><Patients><Pb element><Penetration><Photography><Photoradiation><Physicians><Physiologic><Physiological><Pilot Projects><Population><Position><Positioning Attribute><Procedures><Process><Productivity><Psoriasis><Publishing><Radiology><Radiology Specialty><Redness><Research><Research Personnel><Researchers><Running><Scalp><Scalp structure><Scars><Scientist><Severity of illness><Short Waves><Short wave Infrared Imaging><Short wavelength infrared light imaging><Shortwave Infrared Imaging><Si element><Sight><Silicon><Skin><Skin Cancer><Skin Diseases><Skin Diseases and Manifestations><Skin Imaging><Skin Pigmentation><Skin Tissue><Source><Standardization><Suppurative Hidradenitis><System><Technical Expertise><Technology><Testing><Tissues><Training><Translating><Treatment outcome><Underarm><Universities><Validation><Vision><Visual><Visualization><Washington><Water><Work><absorption><accurate diagnosis><adulthood><base><bases><boil><career><catalyst><chromophore><chronic inflammatory skin><clinic ready><clinical ready><clinical training><cost><cutaneous biopsy><cutaneous disease><cutaneous tissue><dermal disease><dermal disorder><detector><disease severity><experience><faces><facial><group of color><heavy metal Pb><heavy metal lead><human subject><image-based method><imaging><imaging method><imaging modality><improved><in vivo><in vivo confocal microscopy><individual of color><kids><light scattering><malignant skin tumor><medical college><medical schools><meter><microscope imaging><microscopic imaging><microscopy imaging><neoplasia><neoplastic growth><new technology><non-invasive diagnosis><non-invasive diagnostic><non-invasive imaging><noninvasive diagnosis><noninvasive diagnostic><noninvasive imaging><novel><novel technologies><optic imaging><optical><optical imaging><people of color><person of color><pilot study><population of color><pre-clinical><preclinical><professor><psoriasiform><psoriatic><reflectance confocal microscopy><school of medicine><short wave infrared-light imaging><skin biopsy><skin color><skin disorder><success><technical skills><tenure process><tenure track><tissue phantom><validations><virtual><visual function><youngster>

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Maria Catalina Camacho

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 46/100

Likely hiring

Solid budget

Active award

$388,750

FY 2025

Project Title

A computational model for how risk for anxiety and depression influences affective neurodevelopment

Grant Number:

5DP5OD037370-02

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2024

End Date:

7/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Depression and anxiety are associated with alterations in brain networks supporting emotion processing and regulation, including attention (dorsal attention [DAN], ventral attention [VAN]), arousal and focus (cingulo- opercular [CON], saliency [SAL]), and self-regulation (default [DM...

Research Terms

<0-11 years old><Affect><Affective><Age><Anger><Anxiety><Applications Grants><Arousal><Attention><BCL2-Interacting Protein><Brain><Brain Nervous System><Care Givers><Caregivers><Categories><Causality><Child><Child Rearing><Child Youth><Children (0-21)><Cognitive><Collaborations><Complex><Computer Models><Computerized Models><Cues><DP5><Data><Data Collection><Dedications><Depressed mood><Development><Distress><Dorsal><Emotional><Emotional Depression><Emotions><Encephalon><Endogenous Factors><Equipment><Etiology><Faculty><Fear><Frequencies><Fright><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Future><Goals><Grant><Grant Proposals><HRK gene><Harakiri><Home><Informal Social Control><Institution><Intervention><Investigators><Lead><Leadership><Learning><Link><Measures><Mental Depression><Mentors><Mentorship><Methodology><Methods><Modeling><Neural Development><Neurobiology><Nursery Schools><Paper><Parenting><Parenting behavior><Parents><Pattern><Pb element><Position><Positioning Attribute><Psychiatry><Psychological reinforcement><Reaction><Regulation><Reinforcement><Research><Research Design><Research Personnel><Research Resources><Research Training><Researchers><Resources><Risk><Risk Factors><Running><Sampling><Self Regulation><Services><Shapes><Study Type><Technical Expertise><Testing><Training><Universities><University resources><Work><Writing><adolescent depression><adolescents with depression><ages><angers><angry><anxiety symptoms><anxious symptom><care giving><career><caregiving><causation><child depression><childhood anxiety><childhood depression><childhood onset depression><childrearing><computational modeling><computational models><computer based models><computerized modeling><depressed><depressed adolescents><depression><depression in adolescence><depression symptom><depressive><depressive symptoms><developmental><disease causation><experience><fMRI><full professor><gaze><heavy metal Pb><heavy metal lead><high risk><homes><improved><innovate><innovation><innovative><kids><negative affect><negative affectivity><neural><neural imaging><neuro-imaging><neurobiological><neurodevelopment><neuroimaging><neurological imaging><novel><parent><pediatric anxiety><pediatric depression><pre-k><pre-kindergarten><preschool><professor><programs><response><sadness><scaffold><scaffolding><senior faculty><skills><study design><support network><technical skills><youngster><youth anxiety><youth depression>

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Andrew Lee Young

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 46/100

Likely hiring

Solid budget

Active award

$388,750

FY 2025

Project Title

Understanding the Impact of Clonal Hematopoiesis on Aging Human Bone Marrow

Grant Number:

1DP5OD039424-01

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/6/2025

End Date:

7/31/2030

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT Every year there are two million new cases of cancer diagnosed in the United States and 600,000 cancer-related deaths. Preventing the development of cancer, when therapies are more effective, is one of the most potent methods to decrease cancer-related mortality. While the a...

Research Terms

<21+ years old><Adult><Adult Human><Affect><Age><Aging><Anemia><Architecture><Automobile Driving><Award><BCL2-Interacting Protein><Benign><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><Brain Dead><Brain Death><Cancers><Cell Body><Cell division><Cells><Cells Placenta-Tissue><Cessation of life><Clinical><Clonal Evolution><Clonal expansion of hematopoietic cells><Clonal expansion of hematopoietic stem cells><Clonal hematopoietic expansion><Cohort Studies><Collaborations><Colon><Coma Depasse><Communication><Concurrent Studies><Core Facility><DNA mutation><DP5><Death><Dependence><Development><Disease><Disorder><Dysfunction><Early Diagnosis><Elderly><Endowment><Engineering / Architecture><Environment><Environmental Exposure><Erythremia><Esophagus><Fellowship><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Functional disorder><Future><Generalized Growth><Genetic><Genetic Change><Genetic defect><Genetic mutation><Genomics><Goals><Grant><Growth><HRK gene><Harakiri><Hematologic Body System><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematologic Organ System><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematologist><Hematology><Hematopoiesis><Hematopoietic><Hematopoietic Body System><Hematopoietic Cancer><Hematopoietic Cell Tumor><Hematopoietic Cellular Control Mechanisms><Hematopoietic Malignancies><Hematopoietic Neoplasms><Hematopoietic Neoplasms including Lymphomas><Hematopoietic System><Hematopoietic Tumor><Hematopoietic and Lymphoid Cell Neoplasm><Hematopoietic and Lymphoid Neoplasms><Heterogeneity><Human><Human Figure><Human body><Image><Immunity><Immunologic Subtyping><Immunophenotyping><Incidence><Individual><Institution><Intervention><Journals><Life><Liver><Longitudinal Studies><Magazine><Malignant><Malignant - descriptor><Malignant Hematologic Neoplasm><Malignant Hematopoietic Neoplasm><Malignant Neoplasms><Malignant Tumor><Mentors><Methods><Modern Man><Morbidity><Morbidity - disease rate><Mutate><Mutation><Mutation Detection><Nature><Normal Placentoma><Oncogenesis><Oncologist><Organ><Organ Donor><Organ Preservation><Organ Procurements><Osler-Vaquez Disease><Patients><Physiologic><Physiological><Physiopathology><Pilot Projects><Placenta><Placenta Embryonic Tissue><Placentome><Polycythemia Rubra Vera><Polycythemia Vera><Precancerous Conditions><Preleukemia><Premalignant Condition><Premalignant State><Prevalence><Prevention><Process><Publications><Research><Research Design><Research Resources><Research Specimen><Resources><Risk Reduction><Scientific Publication><Shapes><Skin><Solid><Somatic Mutation><Source><Specimen><Study Type><System><Techniques><Technology><Testing><Time><Tissue Donors><Tissue Growth><Tissues><Training><Transplantation><United States><Universities><Washington><Work><adulthood><advanced age><age associated alterations><age associated changes><age correlated alterations><age correlated changes><age dependent alterations><age dependent changes><age induced alterations><age induced changes><age related alterations><age related changes><age specific alterations><age specific changes><ages><aging associated><aging associated alterations><aging associated changes><aging correlated alterations><aging correlated changes><aging dependent alterations><aging dependent changes><aging induced alterations><aging induced changes><aging related><aging related alterations><aging related changes><aging specific alterations><aging specific changes><alterations with age><blood cancer><blood cell formation><bone><bone cell><cancer diagnosis><cancer of blood><cancer of the blood><cancer risk><career><catalyst><cerebral death><changes with age><clonal expansions in the blood><clonal hematopoiesis><clones in hematopoietic cells><developmental><driving><early detection><flow cytophotometry><genome mutation><geriatric><graduate school><healthy aging><healthy human aging><hematopoietic cell clones><hematopoietic stem cell clonality><hemopoietic><hepatic body system><hepatic organ system><imaging><improved><insight><interest><late in life><late life><leukemia><leukemic transformation><leukemogenesis><long-term study><longitudinal outcome studies><low-frequency mutation><malignancy><mid life><mid-life><middle age><middle aged><midlife><molecular diagnostics><mortality><mosaic><neoplasm/cancer><new technology><novel><novel technologies><ontogeny><pathophysiology><peripheral blood><pilot study><precancerous state><prevent><preventing><professor><rare allele><rare mutation><rare variant><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><senior citizen><single cell analysis><skills><somatic variant><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><study design><tech development><technology development><tool><transplant><tumorigenesis><variant detection>

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Violeta de Jesus Rodriguez

UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, CHAMPAIGN, IL

Good lead · 46/100

Likely hiring

Solid budget

Active award

$385,763

FY 2025

Project Title

Optimizing the Assessment of Parenting: A Multi-Method and Multi-Informant Approach

Grant Number:

5DP5OD036508-02

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2024

End Date:

8/31/2029

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Parenting plays a crucial role in youth development, influencing a myriad of health behaviors. As a result, parenting is a common focus of interventions aimed at improving youth health outcomes. Effective parenting interventions and their study necessitate robust assessments of parenting. However, t...

Research Terms

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THOMAS R. HOYE

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 46/100

Likely hiring

Solid budget

Active award

$382,556

FY 2025

Project Title

Synthesis, Structure, and Mechanism of Biorelevant Molecules and Reactions

Grant Number:

5R35GM127097-08

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2018

End Date:

7/31/2028

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT Synthesis, Structure, and Mechanism of Biorelevant Molecules and Reactions Our MIRA-supported research program encompasses synthetic, mechanistic, and structural organic chem- istry. We address unresolved contemporary problems through studies that lead to i) new ways of ded...

Research Terms

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Jacob J Capin

MARQUETTE UNIVERSITY, MILWAUKEE, WI

Good lead · 46/100

Likely hiring

Solid budget

Active award

$376,439

FY 2025

Project Title

Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health

Grant Number:

5DP5OD031833-05

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/22/2021

End Date:

8/31/2026

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT Approximately 8.5 million high school and collegiate athletes engage annually in competitive sport. While competitive sport offers many benefits, it also poses underappreciated risks to long-term health. Competitive sport profoundly increases risk for injury (e.g., knee inju...

Research Terms

<21+ years old><Adult><Adult Human><Age><American><Athletic><BCL2-Interacting Protein><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Body Composition><Body fat><Certification><Chronic Disease><Chronic Illness><Clinical><Conditioning Therapy><Counseling><DP5><Data><Degenerative Arthritis><Degenerative polyarthritis><Delaware><Development><Disease><Disorder><Doctor of Philosophy><Equipment><Exercise><Faculty><Female><Funding><Future><General Population><General Public><Goals><Groups at risk><Guidelines><HRK gene><Harakiri><Health><Health Promotion><History><Injury><Institution><Intervention><Intervention Studies><Knee Injuries><Laboratories><Life><Longitudinal Studies><Manuscripts><Medical><Medical Rehabilitation><Mentors><Methods><Minority><Musculoskeletal><NICHD><NIH><National Institute of Child Health and Human Development><National Institutes of Health><Non-pharmacologic Therapy><Nonpharmacologic Intervention><Nonpharmacologic Therapy><Nonpharmacologic approach><Nonpharmacologic treatment><Osteoarthritis><Osteoarthrosis><Outcome><Participant><Pattern><Peer Review><People at risk><Persons><Persons at risk><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D.><Ph.D. student><PhD><PhD student><PhD. student><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical activity><Physical therapy><Physiotherapy><Play><Population><Populations at Risk><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Procedures><Publications><QOL><Quality of life><Recommendation><Recording of previous events><Rehabilitation><Rehabilitation therapy><Research><Research Assistant><Research Associate><Research Resources><Research Support><Research Training><Resources><Risk><Risk Factors><Salutogenesis><Scientific Publication><Scientist><Sedentary behavior><Sedentary life-style><Services><Sports><Testing><Underrepresented Groups><Underrepresented Populations><United States><United States National Institutes of Health><Universities><Walking><Work><adulthood><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><analyzing longitudinal><behavior intervention><behavioral intervention><cardiometabolic><cardiometabolism><cardiovascular disease risk><cardiovascular disorder risk><career><career development><chronic disorder><chronic pain><cohort><college><collegiate><cost><degenerative joint disease><design><designing><developmental><disability><doctoral student><early onset><enhance healthspan><experience><extend healthspan><extending healthy lifespan><hamstring><health related quality of life><healthspan extension><high school><histories><hypertrophic arthritis><improve healthspan><improved><increase healthspan><injuries><injury of musculoskeletal system (disorder)><injury of musculoskeleted system><innovate><innovation><innovative><intervention research><interventional research><interventional study><interventions research><life span><lifespan><long-term study><longitudinal analysis><longitudinal outcome studies><male><mid life><mid-life><middle age><middle aged><midlife><moderate-to-vigorous physical activity><mortality><musculoskeletal injury><musculoskeletal trauma><non-drug therapy><non-drug treatment><nondrug therapy><nondrug treatment><novel><peer><physical therapist><physiotherapist><population aging><post-doc><post-doctoral><post-doctoral trainee><prevent><preventing><professor><programs><prolong healthspan><promote healthspan><promoting health><quadriceps><quadriceps muscle><rehab therapy><rehabilitative><rehabilitative therapy><research associates><sedentary><sedentary lifestyle><success><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><♀><♂>

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THOMAS S. KUPPER

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Exploratory lead · 38/100

Training-friendly

Solid budget

Active award

$395,858

FY 2025

Project Title

Dermatology Training Grant

Grant Number:

5T32AR007098-51

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

9/1/1980

End Date:

5/31/2027

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The Harvard Medical School Department of Dermatology T32 training grant has been active for more than 45 years, and over that period of time has trained many postdoctoral fellows who have become national leaders in dermatology. Dr. Thomas Kupper has served as Principal Investigator since 2000. There...

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Isha Himani Jain

J. DAVID GLADSTONE INSTITUTES, SAN FRANCISCO, CA

Exploratory lead · 36/100

Likely hiring

Solid budget

$472,500

FY 2022

Project Title

Redesigning a Neuron's Breath: A Modern Twist to Classical Oxygen Biology

Grant Number:

5DP5OD026398-06

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/8/2021

End Date:

8/31/2024

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT Oxygen is one of the most used substrates in the human body. When oxygen deprivation exceeds the buffering capacity of the human body, there are devastating effects on health and survival. For example, three of the five leading causes of death in the US are a consequence of...

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Steve Ramirez

BOSTON UNIVERSITY (CHARLES RIVER CAMPUS), BOSTON, MA

Exploratory lead · 36/100

Likely hiring

Solid budget

$412,500

FY 2021

Project Title

Artificially modulating memories to alleviate psychiatric disease-like states

Grant Number:

5DP5OD023106-07

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2016

End Date:

8/31/2023

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY / ABSTRACT Chronic stress affects numerous brain areas involved in memory, emotion, and motivation, such as the hippocampus, amygdala, and prefrontal cortex; it abnormally alters a variety of cellular events, including dendritic morphology and gene expression patterns; and, it can pr...

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HSIAO-TUAN CHAO

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Exploratory lead · 36/100

Likely hiring

Solid budget

$396,250

FY 2022

Project Title

Illuminating GABAergic Signaling in Neurodevelopmental Disorders

Grant Number:

5DP5OD026428-05

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/18/2018

End Date:

8/30/2025

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY Technological advances have accelerated the discovery of genetic etiologies for many neurodevelopmental disorders such as intellectual disability, autism spectrum disorder, and epilepsy. The emerging theme of altered inhibitory -aminobutyric-acid-(GABA)-ergic signaling in many of th...

Research Terms

<0-11 years old><4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><Acute><Address><Affect><Aminalon><Aminalone><Aminobutyric Acids><Assay><Ataxia><Ataxy><Autism><Autistic Disorder><Award><B-Cells><B-Lymphocytes><B-cell><BCL2-Interacting Protein><Basal Transcription Factor><Basal transcription factor genes><Basic Research><Basic Science><Behavior><Behavioral><Bioassay><Biologic Assays><Biological Assay><Brain><Brain Nervous System><Candidate Disease Gene><Candidate Gene><Causality><Cell Communication and Signaling><Cell Function><Cell Process><Cell Signaling><Cell physiology><Cellular Function><Cellular Physiology><Cellular Process><Child><Child Youth><Childhood Neurological Disorder><Children (0-21)><Clinical><Cognitive><Cognitive deficits><Coordination Impairment><Core Facility><DP5><Decreased Muscle Tone><Degenerative Neurologic Diseases><Degenerative Neurologic Disorders><Development><Diagnosis><Disease><Disorder><Drosophila><Drosophila genus><Drosophila melanogaster><Dysfunction><Dyssynergia><Early Infantile Autism><Encephalon><Environment><Epilepsy><Epileptic Seizures><Epileptics><Equipment><Etiology><Family><Flies><Foundations><Functional disorder><Funding><GABA><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Transcription><Gene variant><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic><Genetic Alteration><Genetic Change><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Susceptibility><Genetic Transcription><Genetic defect><Goals><HRK gene><Harakiri><Health><Human><Human Genetics><Hypomyotonia><Hypotonia><Impairment><Infantile Autism><Inherited Predisposition><Inherited Susceptibility><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interdisciplinary Research><Interdisciplinary Study><Intracellular Communication and Signaling><Investigators><Kanner's Syndrome><Knowledge><Laboratories><Leadership><Mediating><Mediator><Mediator of Activation><Mediator of activation protein><Medicine><Mentorship><Mice><Mice Mammals><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Murine><Mus><Muscle Hypotony><Muscle Tone Poor><Muscle hypotonia><Muscular Hypotonia><Mutation><Nerve Cells><Nerve Unit><Nervous System Degenerative Diseases><Nervous System Diseases><Neural Cell><Neural Degenerative Diseases><Neural Development><Neural degenerative Disorders><Neurobiology><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurodevelopmental Disorder><Neurologic><Neurologic Deficit><Neurologic Degenerative Conditions><Neurologic Disorders><Neurological><Neurological Development Disorder><Neurological Disorder in Children><Neurological Disorders><Neurons><Neurosciences><Pathogenesis><Pathogenicity><Pediatric Neurology><Phenotype><Physicians><Physiopathology><Process><RNA Expression><Regulation><Research><Research Institute><Research Personnel><Research Resources><Researchers><Resources><Role><Salaries><Scientist><Seizure Disorder><Signal Transduction><Signal Transduction Systems><Signaling><Subcellular Process><Syndrome><Technology><Testing><Therapeutic><Transcript Expression Analyses><Transcript Expression Analysis><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Wages><allele variant><allelic variant><autism spectrum disorder><autistic spectrum disorder><biological signal transduction><career><career development><causation><cell type><child neurology><cognitive defects><college><collegiate><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><developmental><disease causation><epilepsia><epileptiform><epileptogenic><fly><fruit fly><gamma-Aminobutyric Acid><gene expression analysis><gene expression assay><gene manipulation><genetic etiology><genetic manipulation><genetic mechanism of disease><genetic variant><genetic vulnerability><genetically manipulate><genetically perturb><genetically predisposed><genome mutation><genomic variant><graduate student><human disease><human genomics><in silico><inhibitory neuron><innovate><innovation><innovative><insight><intellectual and developmental disability><loss of function><mouse model><multidisciplinary><murine model><nervous system disorder><neural><neural network><neurobiological><neurodegenerative illness><neurodevelopment><neurological disease><neuron development><neuronal><neuronal development><neurophysiological><neurophysiology><novel><pathophysiology><relating to nervous system><social role><sq. ft><square foot><transcription factor><transcriptional profiling><virtual><youngster><γ-Aminobutyric Acid>

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Adam Lee Bailey

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

Exploratory lead · 36/100

Likely hiring

Solid budget

$388,750

FY 2024

Project Title

Determinants of yellow fever pathogenesis in humans

Grant Number:

5DP5OD029608-06

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2020

End Date:

8/31/2025

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT Yellow fever (YF) is a deadly disease transmitted by the bite of infected Aedes aegypti mosquitoes. Although an effective vaccine for YF was invented in the 1930s, it is not amenable to large-scale production and has a high rate of adverse events (including death). As a resu...

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Zachary Scott Morris

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

Exploratory lead · 36/100

Likely hiring

Solid budget

$382,500

FY 2021

Project Title

Combining Radiation and Tumor-specific AntIbody Therapies to Elicit in Situ Tumor Vaccination

Grant Number:

5DP5OD024576-05

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2017

End Date:

8/31/2023

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

7. Project Summary/Abstract In a collaborative research project that I initiated between the labs of Prof. Paul Sondel and Prof. Paul Harari during my residency training, we explored a novel approach to augmenting anti-tumor immune response by combining two established cancer treatments, ra...

Research Terms

<Ab-dependent cellular cytotoxicity><Acceleration><Animal Model><Animal Models and Related Studies><Animals><Antibodies><Antibody Therapy><Antibody-Dependent Enhancement><Award><BCL2-Interacting Protein><Binding><CD152><CD152 Antigen><CD152 Gene><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 gene><CTLA4-TM><Cancer Treatment><Cancers><Caring><Cellular Immune Function><Chimera Protein><Chimeric Proteins><Clinical><Clinical Treatment Moab><Co-Stimulator><Coin><Combined Modality Therapy><Consultations><Costimulator><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><DP5><Data><Definitive Radiation Therapy><Disease><Disorder><Distant><Dose><Drug Kinetics><EBRT><Engraftment><Ensure><Epidermal Thymocyte Activating Factor><External Beam RT><External Beam Radiation Therapy><External Radiation><Feedback><Funding><Fusion Protein><Generations><Goals><HNSCC><HRK gene><Harakiri><Head and Neck Carcinoma><Head and Neck Squamous Cell Carcinoma><IFN-gamma-Inducing Factor><IGIF><IL-1 Gamma><IL-18><IL-1g><IL-2><IL18 Protein><IL1F4><IL2 Protein><Immune Tolerance><Immune response><Immune system><Immunologic Tolerance><Immunological response><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Injections><Interferon-gamma-Inducing Factor><Interleukin 18 (Interferon-Gamma-Inducing Factor)><Interleukin 18 Proprotein><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-1 Gamma><Interleukin-18><Interleukin-18 Precursor><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><Intervention><Intervention Strategies><Interview><Intravenous><Investigation><Lymphocyte Mitogenic Factor><MAb Therapeutics><MEL><MEL Gene><MEL Transforming Oncogene Homolog><MGC12320><Malignant Melanoma><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Manuscripts><Mediating><Melanocyte Transforming Oncogene Homolog><Mentors><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Mice><Mice Mammals><Microscopic><Mitogenic Factor><Modeling><Molecular Interaction><Molecular Target><Monoclonal Antibodies><Multimodal Therapy><Multimodal Treatment><Murine><Mus><Neoplasm Metastasis><Neuroblastoma><Patients><Pharmacokinetics><Primary Neoplasm><Primary Tumor><Publications><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><RAB8><RAB8 Homolog><Radiation><Radiation therapy><Radiotherapeutics><Radiotherapy><Regimen><Regulatory T-Lymphocyte><Reporting><Research><Research Grants><Research Project Grants><Research Projects><Residencies><Role><SCCHN><Scientific Publication><Secondary Neoplasm><Secondary Tumor><Secure><Site><T cell growth factor><T cell response><T memory cell><T-Cell Growth Factor><T-Cell Stimulating Factor><T-Cells><T-Lymphocyte><Targeted Radiotherapy><Techniques><Testing><Therapeutic Monoclonal Antibodies><Thymocyte Stimulating Factor><Toxic effect><Toxicities><Training><Transgenic Organisms><Treg><Tumor Cell><allergic/immunologic body system><allergic/immunologic organ system><anti-cancer immunotherapy><anti-cancer therapy><anti-tumor effect><anti-tumor immune response><antibody based therapies><antibody dependent cell mediated cytotoxicity><antibody dependent cytotoxicity><antibody treatment><antibody-based therapeutics><antibody-based treatment><antibody-dependent cell cytotoxicity><antibody-dependent cellular cytotoxicity><antibody-mediated cytotoxicity><anticancer immunotherapy><anticancer therapy><antitumor effect><antitumor immune response><cancer immunotherapy><cancer metastasis><cancer therapy><cancer type><cancer-directed therapy><career development><cartilage link protein><check point blockade><checkpoint blockade><clinical relevance><clinically relevant><combination therapy><combined modality treatment><combined treatment><cytokine><cytotoxic T-lymphocyte antigen 4><design><designing><experiment><experimental research><experimental study><external-beam radiation><head and neck squamous cell cancer><host response><immune check point blockade><immune checkpoint blockade><immune function><immune suppression><immune system response><immune system tolerance><immune unresponsiveness><immune-based cancer therapies><immunological paralysis><immunoresponse><immunotherapy for cancer><immunotherapy of cancer><improved><in situ anti-tumor vaccination><in situ anti-tumor vaccine><in situ antitumor vaccination><in situ antitumor vaccine><in situ cancer vaccination><in situ cancer vaccine><in situ tumor vaccination><in situ tumor vaccine><in situ vaccination><in situ vaccine><in vivo><innovate><innovation><innovative><interventional strategy><link protein><mAbs><malignancy><melanoma><memory T lymphocyte><model of animal><model organism><monoclonal antibody drugs><mouse model><multi-modal therapy><multi-modal treatment><murine model><neoplasm/cancer><neoplastic cell><new approaches><novel approaches><novel strategies><novel strategy><pre-clinical><preclinical><radiation treatment><radio-therapy><regulatory T-cells><response><social role><success><therapeutic mAbs><thymus derived lymphocyte><transgenic><treatment with radiation><tumor><tumor cell metastasis><vaccination strategy><vaccine response>

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Jacob Anthony George

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 36/100

Likely hiring

Solid budget

$381,250

FY 2024

Project Title

Patient-centered rehabilitation and dexterous assistive devices for stroke patients using bionic exoskeletons controlled by non-invasive electromyography

Grant Number:

5DP5OD029571-05

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2020

End Date:

8/31/2025

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY / ABSTRACT Stroke is one of the leading causes of disability worldwide and the most common stroke-related impairment is upper-limb hemiparesis, affecting 80% of stroke patients acutely and 40% chronically. Full recovery is unlikely with current rehabilitation approaches, and as a res...

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Marc Kantorow

FLORIDA ATLANTIC UNIVERSITY, BOCA RATON, FL

Exploratory lead · 36/100

Likely hiring

Solid budget

$370,138

FY 2023

Project Title

Hypoxia Regulation of the Lens

Grant Number:

5R01EY029708-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2019

End Date:

12/31/2024

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract This application seeks to identify novel mechanisms and regulatory pathways required to achieve the structure and function of the eye lens. The lens consists of a surface layer of epithelial cells that during embryogenesis, and throughout life, differentiate into lens fiber ...

Research Terms

<21+ years old><Acceleration><Adult><Adult Human><BCL2-Interacting Protein><Basal Transcription Factor><Basal transcription factor genes><Birth><Blood erythrocyte><Body Tissues><CDK inhibitor p27><CDKN1B protein><CDKN4 protein><Cataract><Cataract Extraction><Cell Body><Cell Components><Cell Cycle><Cell Division Cycle><Cell Structure><Cells><Cellular Regulation><Cellular Structures><Chick><Chick Embryo><Complex><Crystalline Lens><Crystallins><Cyclin-Dependent Kinase Inhibitor p27><DP5><Data><Development><Embryo><Embryo Development><Embryogenesis><Embryonic><Embryonic Development><Endoplasmic Reticulum><Environment><Epithelial Cells><Ergastoplasm><Erythrocytes><Erythrocytic><Event><Exhibits><Eye Lens><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Transcription><Golgi><Golgi Apparatus><Golgi Complex><HIF 1 alpha><HIF-1alpha><HIF1-Alpha><HIF1A><HIF1A gene><HIF1α><HRK gene><Harakiri><Health><Hyperoxia><Hypoxia><Hypoxic><KO mice><Kip1 protein><Knock-out Mice><Knockout Mice><Lens Fiber><Life><Link><MOP1><Marrow erythrocyte><Mice><Mice Mammals><Mitochondria><Murine><Mus><Null Mouse><O element><O2 element><Ocular Lens><Organelles><Oxygen><Oxygen Deficiency><Parkin><Parkin gene><Parturition><Pathology><Pathway interactions><Phosphorylation><Population><Prevention therapy><Protein Phosphorylation><Proteins><RNA Expression><Red Blood Cells><Red Cell><Regulation><Regulatory Pathway><Reporting><Structural Protein><Structure><Surface><Testing><Tissues><Transcription><Transcription Factor Proto-Oncogene><Transcription Regulation><Transcription factor genes><Transcriptional Control><Transcriptional Regulation><Vascular blood supply><Visual><adulthood><blood corpuscles><blood supply><cataract surgery><cataractogenesis><cataractous lenses><cell growth regulation><chicken embryo><cyclin-dependent kinase inhibitor 1B><design><designing><developmental><disability><embryo culture><experiment><experimental research><experimental study><experiments><fiber cell><hyperoxygenation><insight><lens><lens protein><lenses><mitochondrial><mouse model><murine model><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><overexpress><overexpression><p27 Kip1 protein><p27 protein><p27-Kip1><p27Kip1 protein><parkin protein><pathway><programs><protein expression><response><success><transcription factor><vascular supply>

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Perry W Hystad

OREGON STATE UNIVERSITY, CORVALLIS, OR

Exploratory lead · 28/100

Above-average budget

Active award

$595,043

FY 2024

Project Title

PURE-Climate: Identifying and Adapting to Climate Change as a Modifiable Risk Factor for Human Health

Grant Number:

1R56ES035095-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/3/2024

End Date:

8/31/2026

Why this may be worth a closer look

• Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Climate change is the largest global health challenge of the 21st century. Although direct and indirect effects of climate change threaten health worldwide, the impacts will be particularly severe in low and middle-income countries (LMICs). There is an alarming absence of research on climat...

Research Terms

<21+ years old><Active Follow-up><Acute><Adult><Adult Human><Air Pollution><Award><BCL2-Interacting Protein><Chronic><Chronic Disease><Chronic Illness><Climate><Communities><Complex><Country><Cross-Over Designs><Cross-Over Studies><Crossover Design><Crossover Studies><DP5><Data><Data Analyses><Data Analysis><Data Collection><Data Set><Disasters><Disease><Disorder><Droughts><Economic Income><Economical Income><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology><Epidemiology Research><Event><Exposure to><Flooding><Floods><Focus Groups><Frequencies><Funding><Future><Grant><HRK gene><Harakiri><Health><Health Policy><Health Surveys><Hospital Admission><Hospitalization><Household><Human><Incidence><Income><Individual><Infrastructure><Investigators><LMIC><Link><Low-resource area><Low-resource community><Low-resource environment><Low-resource region><Low-resource setting><Meteorological Climate><Methods><Modern Man><NIH><National Institutes of Health><Outcome><Participant><Pathway interactions><Pattern><Prospective cohort><Prospective, cohort study><Rain><Research><Research Design><Research Personnel><Research Resources><Researchers><Resource-constrained area><Resource-constrained community><Resource-constrained environment><Resource-constrained region><Resource-constrained setting><Resource-limited area><Resource-limited community><Resource-limited environment><Resource-limited region><Resource-limited setting><Resource-poor area><Resource-poor community><Resource-poor environment><Resource-poor region><Resource-poor setting><Resources><Risk Factors><Rural><Rural Community><Seasons><Study Type><Survey Instrument><Surveys><Survival Analyses><Survival Analysis><United States National Institutes of Health><active followup><adulthood><analytical method><build resilience><build resiliency><chronic disorder><climate and health><climate change><climate disaster><climate exposure><climate health><climate impact><climate-related disaster><climate-related exposures><climate-related health><climatic><climatic changes><cohort><community factor><community-level factor><data interpretation><develop resilience><develop resiliency><enhance resilience><enhance resiliency><epidemiologic><epidemiologic investigation><epidemiological><epidemiology study><evidence base><experience><extreme temperature><extreme weather><follow up><follow-up><followed up><followup><global climate change><global health><hazard><health care policy><healthcare policy><improve resilience><improve resiliency><incomes><increase resilience><increase resiliency><low and middle-income countries><malleable risk><meteorological data><modifiable risk><mortality><pathway><promote resilience><promote resiliency><prospective><rainfall><resilience><resilience development><resilience factor><resiliency factor><resilient><study design><weather data>

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Xiao-Ou Shu

VANDERBILT UNIVERSITY MEDICAL CENTER, NASHVILLE, TN

Exploratory lead · 28/100

Training-friendly

Solid budget

$490,281

FY 2021

Project Title

Vanderbilt Training Program in Molecular and Genetic Epidemiology of Cancer

Grant Number:

5T32CA160056-11

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

9/1/2017

End Date:

6/30/2023

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

ABSTRACT The rapid development and advancement of technologies and knowledge in molecular biology and genetics have led to major breakthroughs in cancer etiology research. While the field of cancer epidemiology is moving rapidly toward a new era in which interdisciplinary and multidisciplinary colla...

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Marie Anne Bakitas

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

Exploratory lead · 28/100

Training-friendly

Solid budget

$480,426

FY 2021

Project Title

UAB Cancer Prevention and Control Training Program (T32)

Grant Number:

5T32CA047888-32

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/13/2018

End Date:

6/30/2023

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

In 1988, the University of Alabama at Birmingham (UAB) Cancer Prevention and Control Training Program (CPCTP) was established under an R25 mechanism and has trained 154 pre- and post-doctoral fellows over the past 28 years. Located in the Deep South, an area marked by poverty and health disparities,...

Research Terms

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Wendy Demark-Wahnefried

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

Exploratory lead · 28/100

Training-friendly

Solid budget

$480,426

FY 2021

Project Title

UAB Cancer Prevention and Control Training Program (T32)

Grant Number:

5T32CA047888-32

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/13/2018

End Date:

6/30/2023

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

In 1988, the University of Alabama at Birmingham (UAB) Cancer Prevention and Control Training Program (CPCTP) was established under an R25 mechanism and has trained 154 pre- and post-doctoral fellows over the past 28 years. Located in the Deep South, an area marked by poverty and health disparities,...

Research Terms

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Ritu Aneja

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

Exploratory lead · 28/100

Training-friendly

Solid budget

$443,963

FY 2022

Project Title

UAB Cancer Prevention and Control Training Program (T32)

Grant Number:

5T32CA047888-33

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/13/2018

End Date:

6/30/2024

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

In 1988, the University of Alabama at Birmingham (UAB) Cancer Prevention and Control Training Program (CPCTP) was established under an R25 mechanism and has trained 154 pre- and post-doctoral fellows over the past 28 years. Located in the Deep South, an area marked by poverty and health disparities,...

Research Terms

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Ellen Mary Lavoie Smith

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

Exploratory lead · 28/100

Training-friendly

Solid budget

$443,963

FY 2022

Project Title

UAB Cancer Prevention and Control Training Program (T32)

Grant Number:

5T32CA047888-33

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/13/2018

End Date:

6/30/2024

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

In 1988, the University of Alabama at Birmingham (UAB) Cancer Prevention and Control Training Program (CPCTP) was established under an R25 mechanism and has trained 154 pre- and post-doctoral fellows over the past 28 years. Located in the Deep South, an area marked by poverty and health disparities,...

Research Terms

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Seung Ha Nam

WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY

Exploratory lead · 26/100

Likely hiring

$110,587

FY 2022

Project Title

Defining malignant hematopoiesis via single-cell multi-omics - DP5 diversity supplement application

Grant Number:

3DP5OD029619-03S1

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2020

End Date:

8/31/2025

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY / ABSTRACT Clonal blood differentiation through the acquisition of somatic mutations result in abnormal accumulation of blood components and clinically manifest as myeloid disorders. The study of how these somatic mutations perturb the differentiation trajectories in human hematopoie...

Research Terms

<55-kDa High-Affinity Calcium Binding Protein><Admixture><Advisory Committees><Affect><Anatomic><Anatomic Sites><Anatomic structures><Anatomical Sciences><Anatomy><Appointment><Assay><BCL2-Interacting Protein><Basal Transcription Factor><Basal transcription factor genes><Bears><Bioassay><Biochemical><Biologic Assays><Biological Assay><Biomedical Research><Blood><Blood Cells><Blood Diseases><Blood Precursor Cell><Blood Reticuloendothelial System><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><CAB-63><CD34><CD34 gene><Calcium-Binding Protein-3><Calregulin><Cell Body><Cell Communication and Signaling><Cell Cycle><Cell Division Cycle><Cell Function><Cell Process><Cell Signaling><Cell physiology><Cell surface><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chromatin><Clinical><Communities><Complex><Core Facility><DNA><DNA Alteration><DNA Sequence Alteration><DNA mutation><DP5><Data><Deoxyribonucleic Acid><Dependence><Development><Diagnostic><Disease><Disorder><ERp60><Environment><Environmental Factor><Environmental Risk Factor><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Exhibits><Expression Signature><Faculty><Funding><Gene Alteration><Gene Expression Profile><Gene Mutation><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic><Genetic Alteration><Genetic Change><Genetic Transcription><Genetic defect><Genetic mutation><Genome><Genomic medicine><Genomics><Genotype><HACBP><HPCA1><HRK gene><Harakiri><Hematologic Diseases><Hematological Disease><Hematological Disorder><Hematopathology><Hematopoiesis><Hematopoietic><Hematopoietic Cell Tumor><Hematopoietic Cellular Control Mechanisms><Hematopoietic Malignancies><Hematopoietic Neoplasms><Hematopoietic Neoplasms including Lymphomas><Hematopoietic Progenitor Cells><Hematopoietic Tumor><Hematopoietic and Lymphoid Cell Neoplasm><Hematopoietic and Lymphoid Neoplasms><Hematopoietic stem cells><Human><Immune><Immune Modulation Therapy><Immunes><Immunoglobulin Enhancer-Binding Protein><Immunologic Factors><Immunological Factors><Individual><Inorganic Chemistry><Institutes><Intracellular Communication and Signaling><Intrinsic factor><Investigation><Investigators><Laboratories><Lead><Link><MPL gene><MPLV><MSKCC><Malignant><Malignant - descriptor><Malignant Hematopoietic Neoplasm><Medicine><Memorial Sloan-Kettering Cancer Center><Mentors><Modern Man><Modernization><Molecular><Molecular Genetics><Morphology><Mouse Homolog of Myeloproliferative Leukemia Virus><Mutate><Mutation><Myelogenous><Myeloid><Myeloid Disease><Myeloid Malignancy><Myeloid Neoplasm><Myeloid Tumor><Myeloproliferative Disorders><Myeloproliferative Leukemia Virus Oncogene><Myeloproliferative Tumors><Myeloproliferative disease><NF-kB><NF-kappa B><NF-kappaB><NFKB><NIH><National Institutes of Health><Nature><Neoplastic Processes><New York><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Outcome><Output><Pathology><Pathway interactions><Patients><Pb element><Peer Review><Peripheral Blood Cell><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D. student><PhD student><PhD. student><Physicians><Population><Process><Progenitor Cells><Protein Secretion><Proteins><Publications><RNA Expression><Research><Research Personnel><Research Resources><Research Specimen><Research Training><Researchers><Resources><Sampling><Scientific Publication><Scientist><Sequence Alteration><Signal Transduction><Signal Transduction Systems><Signaling><Somatic Mutation><Specialty><Specimen><Subcellular Process><Supervision><T-Cells><T-Lymphocyte><TPOR><Task Forces><Technology><Testing><Therapeutic Intervention><Thrombopoietin Receptor><Tissues><Training><Transcription><Transcription Factor NF-kB><Transcription Factor Proto-Oncogene><Transcription factor genes><Translational Research><Translational Science><Trees><Tumor Cell><United States National Institutes of Health><Ursidae><Ursidae Family><advisory team><bear><biobank><biological signal transduction><biorepository><blood cancer><blood cell formation><blood disorder><blood stem cell><cC1qR Protein><calreticulin><cell type><clinical phenotype><college><collegiate><cytokine><developmental><disease phenotype><doctoral student><driver lesion><driver mutation><environmental risk><epigenome><epigenomics><gene expression pattern><gene expression signature><genome mutation><genomic alteration><global gene expression><global transcription profile><heavy metal Pb><heavy metal lead><hematopoietic differentiation><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic><hemopoietic progenitor><hemopoietic stem cell><immune modulating therapies><immune modulatory therapies><immune-modulation treatment><immunologic substance><immunological substance><immunomodulation therapy><immunomodulation treatment><immunomodulatory therapies><immunomodulatory therapy><immunomodulatory treatment><improved><innovate><innovation><innovative><insight><intervention therapy><kappa B Enhancer Binding Protein><medical college><medical schools><medical specialties><molecular array><mouse model><multidisciplinary><multiomics><multiple omics><murine model><mutant><myeloproliferative neoplasm><neoplastic><neoplastic cell><next generation><novel><nuclear factor kappa beta><pathway><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><progenitor><programs><response><school of medicine><single cell sequencing><stem cells><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><thymus derived lymphocyte><tool><transcription factor><transcriptional profile><transcriptional signature><transcriptome><transcriptomics><translation research><undergrad><undergraduate><undergraduate student>

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Robert M Samstein

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

Exploratory lead · 26/100

Likely hiring

$101,673

FY 2023

Project Title

Dissecting the influence of DNA damage response and homologous recombination deficiencies on tumor immunogenicity

Grant Number:

3DP5OD028171-05S1

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/16/2019

End Date:

8/31/2024

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY This Diversity Supplement will support the career development of Ezekiel Olumuyide who will perform PhD thesis studies under the mentorship of Robert Samstein. The parent grant (DP5 grant OD028171, “Dissecting the influence of DNA damage response and homologous recombination deficien...

Research Terms

<BCL2-Interacting Protein><Bar Codes><Biomedical Research><CRISPR editing screen><CRISPR screen><CRISPR-based screen><CRISPR/Cas9 screen><Communication><Complement><Complement Proteins><DNA Damage><DNA Damage Repair><DNA Injury><DNA Repair><DP5><Defect><Development Plans><Doctor of Philosophy><Genes><Goals><Grant><HRK gene><Harakiri><Immunologic Subtyping><Immunology><Immunophenotyping><Innate Immune Response><Mentorship><Oral><Ph.D.><PhD><Population Heterogeneity><Proteins><Technical Expertise><Technology><Training><Unscheduled DNA Synthesis><Work><Writing><adaptive immune response><barcode><career><career development><clustered regularly interspaced short palindromic repeats screen><diverse populations><heterogeneous population><homologous recombination><immunogenicity><immunophenotype><mouse model><murine model><novel><parent grant><population diversity><response><skill acquisition><skill development><technical skills><tumor>

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David W Walker

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Exploratory lead · 26/100

Likely hiring

$100,813

FY 2025

Project Title

Role of Mitochondrial Homeostasis in Animal Aging

Grant Number:

3R01AG037514-13S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2010

End Date:

7/31/2025

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary As advanced age is the most significant risk factor for Alzheimer’s disease (AD), targeting detrimental age-related processes may lead to effective therapies. Mitochondrial dysfunction and pro-inflammatory signaling are each thought to be key drivers of aging and AD. However, a clear...

Research Terms

<21+ years old><AD dementia><AD model><AD pathology><AD related dementia><ADRD><Acids><Adult><Adult Human><Age of Onset><Aging><Agonist><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer risk factor><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's brain><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease brain><Alzheimer's disease model><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's disease risk><Alzheimer's pathology><Alzheimer's patient><Alzheimers Dementia><Animals><Autophagocytosis><Autoregulation><BCL2-Interacting Protein><Binding Proteins><Biological><Body System><Body Tissues><Brain><Brain Nervous System><Cell Communication and Signaling><Cell Signaling><Cell model><Cellular model><Cytosol><DNA><DNA Nucleases><DNase><DP5><Deoxyribonucleases><Deoxyribonucleic Acid><Development><Drosophila><Drosophila genus><Elderly><Encephalon><Flies><Genetic><Goals><HRK gene><Harakiri><Health><Homeostasis><Immune Cell Activation><Immune signaling><Immune system><Immunoglobulin Enhancer-Binding Protein><Increase lifespan><Inflammation><Inflammatory><Inflammatory Response><Innate Immune Response><Innate Immune System><Intracellular Communication and Signaling><Knowledge><Ligand Binding Protein><Ligand Binding Protein Gene><Link><Lysosomes><Mammalia><Mammals><Mediating><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Mitochondria><Mitochondrial DNA><Molecular><NF-kB><NF-kappa B><NF-kappaB><NFKB><Nerve Cells><Nerve Unit><Nervous System><Neural Cell><Neurocyte><Neurologic Body System><Neurologic Organ System><Neurons><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Onset of illness><Organ System><Outer Mitochondrial Membrane><Pathogen detection><Pathogenesis><Pathology><Physiological Homeostasis><Prevalence><Primary Senile Degenerative Dementia><Process><Protein Binding><Reporting><Research><Research Design><Respiratory Chain><Risk Factors><Role><Signal Transduction><Signal Transduction Systems><Signaling><Stress><Study Type><Surface Proteins><System><Therapeutic Intervention><Tissues><Transcription Factor NF-kB><Upregulation><Work><adulthood><advanced age><age associated><age associated disease><age associated disorder><age associated impairment><age correlated><age dependent><age dependent disease><age dependent disorder><age dependent impairment><age linked><age related><age related human disease><age related pathways><age reversal><age specific><age-related disease><age-related disorder><age-related impairment><aged><aged brain><aging associated><aging associated mechanism><aging brain><aging mechanism><aging pathway><aging related><aging related mechanism><aging related pathways><aging reversal><alleviate age related><alleviate aging><alzheimer model><alzheimer risk><ameliorating aging><autophagy><biologic><biological mechanism of age><biological pathways of age><biological signal transduction><boost longevity><bound protein><counter age related><counter aging><counteract age related><counteract aging><developmental><disease onset><disorder onset><drivers of aging><effective therapy><effective treatment><elongating the lifespan><enhance longevity><extend life span><extend lifespan><extend longevity><fly><foster longevity><fruit fly><genetic approach><genetic strategy><geriatric><gerodriver><hallmarks of aging><healthspan><healthy life span><immune activation><improve lifespan><improve longevity><intervention therapy><kappa B Enhancer Binding Protein><lifespan extension><mechanism regulating aging><mechanisms involved in aging><mitochondrial><mitochondrial autophagy><mitochondrial dysfunction><mtDNA><neural inflammation><neuroinflammation><neuroinflammatory><neuronal><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutic target><new therapeutics><new therapy><new therapy approaches><new therapy target><new treatment approach><new treatment strategy><next generation therapeutics><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutic target><novel therapeutics><novel therapy><novel therapy approach><novel therapy target><nuclear factor kappa beta><pathway involved in aging><patient living with Alzheimer's disease><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><pillars of aging><prevent><preventing><primary degenerative dementia><prolong lifespan><prolong longevity><promote lifespan><promote longevity><reverse age><reverse aging><reverse aging effects><reversible aging><senile dementia of the Alzheimer type><senior citizen><sensor><social role><study design><support longevity><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment>

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Jacob Anthony George

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 26/100

Likely hiring

$82,532

FY 2024

Project Title

Patient-centered rehabilitation and dexterous assistive devices for stroke patients using bionic exoskeletons controlled by non-invasive electromyography

Grant Number:

3DP5OD029571-05S1

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2020

End Date:

8/31/2025

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY / ABSTRACT Stroke is one of the leading causes of disability worldwide and the most common stroke-related impairment is upper-limb hemiparesis, affecting 80% of stroke patients acutely and 40% chronically. Full recovery is unlikely with current rehabilitation approaches, and as a res...

Research Terms

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KRISHNA MOORTHI BHAT

UNIVERSITY OF SOUTH FLORIDA, TAMPA, FL

Exploratory lead · 26/100

Likely hiring

$81,705

FY 2023

Project Title

Functional role of Sec20, a BH3 and Secretory (Sec) domain protein, in neurons and its relevance to a motor neuron disease in Drosophila

Grant Number:

1RF1NS131315-01

Activity Code:

RF1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/15/2023

End Date:

2/29/2024

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

This proposal examines the functional role of Sec20, a BH3 and Secretory (Sec) domain protein, in neurons and its relevance to a motor neuron disease using Drosophila. It also examines the interaction between sec20 and GGGGCC (G4C2) repeats of the gene C9orf72 (Chromosome9 open reading frame), a wel...

Research Terms

<21+ years old><Adenoviridae><Adenoviruses><Adult><Adult Human><Affect><Amentia><Amyotrophic Lateral Sclerosis><Amyotrophic Lateral Sclerosis Motor Neuron Disease><Amyotrophic lateral sclerosis and frontotemporal degeneration><Amyotrophic lateral sclerosis and frontotemporal dementia><Apoptosis><Apoptosis Pathway><Apoptotic><Autophagocytosis><Autophagosome><B-Cell CLL/Lymphoma 2 Gene><B-cell lymphoma/leukemia-2><BCL2><BCL2 gene><BCL2-Interacting Protein><Bcl-2><Bioenergetics><Biologic Models><Biological Models><Biology><Brain><Brain Diseases><Brain Disorders><Brain Nervous System><C9ORF72><Cell Death><Cessation of life><Chromosomes><Citrate (si)-Synthase><Citrate Synthase><Collaborations><DNA Molecular Biology><DP5><Data><Death><Defect><Degenerative Neurologic Diseases><Degenerative Neurologic Disorders><Dementia><Development><Disease><Disorder><Drosophila><Drosophila genus><Encephalon><Encephalon Diseases><Erythrocuprein><Eye><Eyeball><FTD/ALS><FTLD/ALS><Failure><Female><Flies><Frontal Temporal Dementia><Frontotemporal Dementia><Frontotemporal Lobar Degeneration/Amyotrophic lateral sclerosis><GWA study><GWAS><Gehrig's Disease><Genes><Genetic><Genetic Alteration><Genetic Change><Genetic Models><Genetic defect><Glutamates><Goals><HRK gene><Harakiri><Health><Hemocuprein><Human><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Knowledge><L-Glutamate><Link><Lou Gehrig Disease><Lysosomes><Mediating><Mission><Mitochondria><Model System><Modern Man><Molecular><Molecular Biology><Motor Cell><Motor Neuron Disease><Motor Neurons><Movement><Mutation><NIH><National Institutes of Health><Nerve Cells><Nerve Unit><Nervous System><Nervous System Degenerative Diseases><Nervous System Diseases><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurobiology><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Body System><Neurologic Degenerative Conditions><Neurologic Disorders><Neurologic Organ System><Neurological Disorders><Neurology><Neurons><ORFs><Open Reading Frames><Ortholog><Orthologous Gene><Pathology><Patients><Peptide Domain><Phenotype><Play><Programmed Cell Death><Protein Coding Region><Protein Domains><Protein Family><Proteins><Public Health><Publishing><Reporting><Risk Factors><Role><Sampling><Superoxide Dismutase><System><Techniques><Tertiary Protein Structure><United States National Institutes of Health><Work><adulthood><amyotrophic lateral sclerosis with frontotemporal dementia><amyotrophic lateral sclerosis/FTLD><amyotrophic lateral sclerosis/frontotemporal dementia><amyotrophic lateral sclerosis/ftd><apoptosis of neuronal cells><autophagy><bcl-2 Genes><body movement><ced9 homolog><cell transformation><chromosome 9 open reading frame 72><cytocuprein><degenerative diseases of motor and sensory neurons><degenerative disorder of motor neurons><degenerative neurological diseases><developmental><fly><front temporal dementia><frontal lobe dementia><frontotemporal dementia-amyotrophic lateral sclerosis><frontotemporal lobar dementia><frontotemporal lobar dementia amyotrophic lateral sclerosis><frontotemporal lobe degeneration associated with dementia><fruit fly><gene function><genome mutation><genome wide association><genome wide association scan><genome wide association studies><genome wide association study><genomewide association scan><genomewide association studies><genomewide association study><glutamatergic><insight><knock-down><knockdown><loss of function><male><member><mitochondrial><mitochondrial dysfunction><motoneuron><motor deficit><motor disease><motor disorder><motor dysfunction><motor neuron function><mouse model><murine model><mutant><necrocytosis><nerve cell death><nerve cell loss><nervous system disorder><neurobiological><neurodegenerative illness><neurological disease><neuron apoptosis><neuron cell death><neuron cell loss><neuron death><neuron loss><neuronal><neuronal apoptosis><neuronal cell death><neuronal cell loss><neuronal cells programmed cell death><neuronal death><neuronal loss><neuronal survival><neurons programmed cell death><prevent><preventing><pro-apoptotic protein><programmed cell death of neuronal cells by apoptosis><programmed cell death of neurons by apoptosis><recruit><social role><tool><transformed cells><whole genome association analysis><whole genome association studies><whole genome association study>

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Jacob Anthony George

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Exploratory lead · 26/100

Likely hiring

$74,813

FY 2023

Project Title

Patient-centered rehabilitation and dexterous assistive devices for stroke patients using bionic exoskeletons controlled by non-invasive electromyography

Grant Number:

3DP5OD029571-04S1

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2020

End Date:

8/31/2025

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY / ABSTRACT Stroke is one of the leading causes of disability worldwide and the most common stroke-related impairment is upper-limb hemiparesis, affecting 80% of stroke patients acutely and 40% chronically. Full recovery is unlikely with current rehabilitation approaches, and as a res...

Research Terms

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Jasper Heinsbroek

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Exploratory lead · 26/100

Likely hiring

$27,218

FY 2023

Project Title

Dissecting Ventral Pallidal Subcircuit Contributions to Drug Seeking in Addiction

Grant Number:

5DP5OD026407-05

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2019

End Date:

4/1/2023

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Drug addiction is a pervasive health problem in our society. We still lack specific therapeutic interventions to break the recurrent pattern of relapse to drug seeking that characterizes the disorder; a result of poor understanding of the neural circuits and cellular adaptations responsible...

Research Terms

<4-Aminobutanoic Acid><4-Aminobutyric Acid><4-amino-butanoic acid><Acceleration><Alien Registration Receipt Card I-55><Aminalon><Aminalone><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Anatomic Sites><Anatomic structures><Anatomy><Area><Automobile Driving><Award><BCL2-Interacting Protein><Basal Ganglia><Basal Nuclei><Behavior><Behavioral><Brain><Brain Nervous System><Breeding><Calcium><Cell Nucleus><Cessation of life><Chemical Dependence><Chronic><DP5><Data><Death><Disease><Disorder><Dissection><Doctor of Philosophy><Drug Addiction><Drug Controls><Drug Dependence><Drug Dependency><Drug abuse><Drug usage><Drugs><Electrophysiology><Electrophysiology (science)><Elements><Emotional><Encephalon><Environment><Equilibrium><Faculty><GABA><Genetic><Globus Pallidus><Glutamates><Green Card><HRK gene><Harakiri><Health><In Vitro><Influentials><Institution><Investigators><L-Glutamate><Label><Learning><Maps><Measures><Medication><Medicine><Mentors><Mice><Mice Mammals><Microscopy><Monitor><Murine><Mus><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurophysiology / Electrophysiology><Neurosciences><Nucleus><Nucleus Accumbens><Overdose><Pathway interactions><Pattern><Ph.D.><PhD><Pharmaceutic Preparations><Pharmaceutical Preparations><Physiology><Population><Population Sizes><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Process><Rabies><Recurrence><Recurrent><Regulation><Relapse><Reporter><Research><Research Associate><Research Personnel><Research Resources><Researchers><Resources><Rewards><Role><Self Administered><Self Administration><Series><Slice><Societies><Stimulus><Structure><Synapses><Synaptic><Technology><Thalamic structure><Thalamus><Therapeutic Intervention><Training><United States><Ventral Tegmental Area><Viral><abuse of drugs><abused drug><abused drugs><abuses drugs><addiction><addictive disorder><amygdaloid nuclear complex><animal colonies><animal colony><balance><balance function><career><cell type><cocaine relapse><cocaine self-administration><college><collegiate><driving><drug abused><drug craving><drug of abuse><drug relapse><drug use><drug/agent><drugs abused><drugs of abuse><electrophysiological><emotional stimulus><experiment><experimental research><experimental study><experiments><gamma-Aminobutyric Acid><global health><glutamatergic><graduate student><illicit drug use><in vivo><interest><intervention therapy><lyssa><motivated behavior><mouse model><murine model><neural adaptation><neural circuit><neural circuitry><neuroadaptation><neurocircuitry><neuronal><neuropsychiatric disease><neuropsychiatric disorder><novel><operation><operations><optogenetics><pallidum><pathway><post-doc><post-doctoral><post-doctoral trainee><post-doctoral training><postdoctoral training><professor><programs><relapse against cocaine><research associates><self-administer cocaine><social role><synapse><synaptic circuit><synaptic circuitry><thalamic><tool><ventral tegmentum><γ-Aminobutyric Acid>

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Margaux Pinney

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 26/100

Likely hiring

$1

FY 2025

Project Title

Leveraging Adaptive Evolution and High-Throughput Techniques to Dissect the Link Between Biochemical Function and Fitness

Grant Number:

4DP5OD033413-04

Activity Code:

DP5

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/13/2022

End Date:

9/2/2025

Why this may be worth a closer look

• Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT Enzymes are the primary functional molecules in cells, providing enormous rate enhancements, specificity and regulation to the diverse chemical reactions that are necessary for life. Enzymes, like all biological macromolecules, are the products of evolution: all enzymes hav...

Research Terms

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Melissa Arbuckle

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$216,000

FY 2022

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

5R25MH086466-14

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/28/2025

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eduardo David Leonardo

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$216,000

FY 2022

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

5R25MH086466-14

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/28/2025

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HAROLD A. PINCUS

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$216,000

FY 2022

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

5R25MH086466-14

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/28/2025

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Melissa Arbuckle

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$16,200

FY 2022

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

3R25MH086466-14S1

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/29/2024

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eduardo David Leonardo

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$16,200

FY 2022

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

3R25MH086466-14S1

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/29/2024

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HAROLD A. PINCUS

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$16,200

FY 2022

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

3R25MH086466-14S1

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/29/2024

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Melissa Arbuckle

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$15,119

FY 2021

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

3R25MH086466-13S1

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/28/2023

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Eduardo David Leonardo

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$15,119

FY 2021

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

3R25MH086466-13S1

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/28/2023

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HAROLD A. PINCUS

NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NEW YORK, NY

Exploratory lead · 18/100

Training-friendly

$15,119

FY 2021

Project Title

Priming the Pump: Training Physician-Scientists in Translational Psychiatry

Grant Number:

3R25MH086466-13S1

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2009

End Date:

2/28/2023

Why this may be worth a closer look

• Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY This proposal aims to continue and improve upon a residency training research track with the explicit goal of recruiting MD/PhD and medical graduates with a track record in conducting research. The program provides early exposure to clinical research in psychiatry to stimulate intere...

Research Terms

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Haijun Gao

HOWARD UNIVERSITY, WASHINGTON, DC

Exploratory lead · 10/100

Active award

$154,500

FY 2025

Project Title

Roles of Placental Mitochondria in the Vicious Cycle of Diabetes and Pregnancy

Grant Number:

5R16HD116702-02

Activity Code:

R16

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2024

End Date:

6/30/2028

Project Abstract

PROPOSAL ABSTRACT Type II diabetes mellitus (T2D) with increasing prevalence represents a major burden for health and care system and individuals. However, the root cause of T2D has not been understood completely. Recent human epidemiological studies indicate that gestational diabetes mellitus (GDM)...

Research Terms

<21+ years old><9-Octadecenoic Acid><Abnormal Assessment of Metabolism><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Affect><Animal Model><Animal Models and Related Studies><Assay><B9 endocrine pancreas><BCL2-Interacting Protein><Beta Cell><Bioassay><Biological Assay><Body Tissues><Body fat><Catabolism><Cell Body><Cell Growth in Number><Cell Multiplication><Cell Proliferation><Cells><Cells Placenta-Tissue><Cellular Proliferation><Closure by Ligation><Control Groups><D-Glucose><DP5><Development><Dextrose><Diabetes Mellitus><Disease><Disorder><Economic Burden><Endocrine Pancreas><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Fetus><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Glucose><Glucose Intolerance><Glucose tolerance test><Goals><H2O2><HRK gene><Harakiri><Health><Health system><Human><Hydrogen Peroxide><Hydroperoxide><IPGTT><Immunoblotting><Immunofluorescence><Immunofluorescence Immunologic><Impairment><In vivo analysis><Individual><Insulin Cell><Insulin Resistance><Insulin Secreting Cell><Islands of Langerhans><Islets of Langerhans><Ketosis-Resistant Diabetes Mellitus><Knock-out><Knockout><Lentivirinae><Lentivirus><Ligation><Lipids><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maturity-Onset Diabetes Mellitus><Measures><Mediating><Mediator><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Studies><Metabolism Studies><Mice><Mice Mammals><Mitochondria><Modeling><Modern Man><Mothers><Murine><Mus><NIDDM><NMR Imaging><NMR Tomography><Nesidioblasts><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Nuclear Magnetic Resonance Imaging><Obesity><Oleic Acids><Organ><Pancreas><Pancreatic><Pancreatic Islets><Pancreatic beta Cell><Pancreatic β-Cell><Pars endocrina pancreatis><Pathway interactions><Phenotype><Placenta><Placenta Embryonic Tissue><Placental Development><Placentation><Placentome><Play><Pregnancy><Pregnancy Maintenance><Pregnancy-Induced Diabetes><Prevalence><Prevention><Process><Production><Role><Slow-Onset Diabetes Mellitus><Stable Diabetes Mellitus><Staining method><Stains><Structure of beta Cell of islet><T2 DM><T2D><T2DM><Testing><Therapeutic><Thesaurismosis><Time><Tissues><Transfection><Transmission Electron Microscopy><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Weaning><Western Blotting><Western Immunoblotting><Woman><Zeugmatography><adiposity><adult onset diabetes><adulthood><care services><care systems><cis-9-Octadecenoic Acid><compare to control><comparison control><corpulence><cytotrophoblast><design><designing><developmental><diabetes><epidemiologic investigation><epidemiology study><fat metabolism><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><glucose tolerance><human tissue><in vivo evaluation><in vivo testing><insight><insulin resistant><insulin secretion><insulin sensitivity test><insulin tolerance><insulin tolerance test><insulin-induced hypoglycemia test><intraperitoneal glucose tolerance test><ketosis resistant diabetes><knock-down><knockdown><lipid metabolism><maintain pregnancy><male><maturity onset diabetes><metabolic abnormality assessment><metabolism disorder><mitochondrial><mitochondrial dysfunction><model of animal><mouse model><murine model><novel><offspring><pancreas beta cell><pancreas β cell><pancreatic b-cell><pathway><placental protein 3><pregnancy diabetes><pregnant><protein blotting><shRNA><short hairpin RNA><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><trophoblast><type 2 DM><type II DM><type two diabetes><β-cell><β-cells><βCell><♂>

View Full Project Details on NIH Reporter

Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

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