NIH Grant Search by PI — Funded Principal Investigator Finder

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Enter a research topic, disease, or technology to find principal investigators with NIH funding in that area. To look up a specific PI by name, use the PI Funding Status check.

Search Results

Found 20 principal investigators from 44 displayed projects for "DP1" (20212026)

Opportunity Digest

Heuristic scoring to help trainees and job seekers prioritize which labs to inspect first.

5

High-opportunity leads

16

Likely hiring signals

1

Training-friendly awards

45

Average opportunity score

This result set has several strong leads. Start with the highest-scoring labs before broadening your search.

Filter for opportunity type

LINDA CHANG

UNIVERSITY OF MARYLAND BALTIMORE, BALTIMORE, MD

High-opportunity lead · 80/100
Likely hiring
Large award
Very recent
Active award
$1,081,500
FY 2026

Project Title

MR-guided focused ultrasound to eradicate CNS viral reservoirs and promote neurogenesis in the HIV-infected brain

Grant Number:

5DP1DA053719-05

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2021

End Date:

4/30/2027

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Large budget suggests more room for personnel or project growth.
  • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary: This DP1 application responds to PAR-20-221 “NIDA Avant-Garde Award Program for HIV/AIDS and Substance Use Disorder Research”. The PI, Linda Chang, proposes to tackle a major challenge in the treatment or cure for HIV, namely, the inability of current treatment regimens to eradicate...

Research Terms

<AIDS Virus><AIDS/HIV><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Anti-Retroviral Agents><Award><Benign Essential Tremor><Binding><Blood - brain barrier anatomy><Blood-Brain Barrier><Brain><Brain Nervous System><CNS Nervous System><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cas nuclease technology><Central Nervous System><Clinical><Clinical Trials><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><DNA><Deoxyribonucleic Acid><Development><Drugs><Emergent Technologies><Emerging Technologies><Encephalon><Ensure><Essential Tremor><Focused Ultrasound><HIV><HIV 1 associated neurocognitive disorder><HIV associated neurocognitive deficit><HIV associated neurocognitive impairment><HIV cure><HIV functional cure><HIV individuals><HIV induced neurocognitive deficit><HIV induced neurocognitive impairment><HIV infected individuals><HIV infected persons><HIV neurocognitive impairment><HIV people><HIV positive individuals><HIV positive people><HIV-1 associated neurocognitive deficit><HIV-1 associated neurocognitive disorder><HIV-1 associated neurocognitive impairment><HIV-1 cure><HIV-1 functional cure><HIV-associated neurocognitive disorder><HIV/AIDS><HIV/AIDS cure><Hemato-Encephalic Barrier><Hortega cell><Human><Human Immunodeficiency Viruses><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Maryland><Medication><Microglia><Modern Man><Molecular Interaction><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Nervous System Diseases><Nervous System Disorder><Neuraxis><Neurocognitive Impairment in HIV><Neurocognitive Impairment in HIV-1><Neurologic Disorders><Neurological Disorders><PLWH><PWH><Paralysis Agitans><Parkinson><Parkinson Disease><Patients><Pattern><Pharmaceutical Preparations><Physiologic pulse><Preclinical data><Primary Parkinsonism><Pulse><Research><Research Resources><Resources><Rodent><Rodent Model><Rodentia><Rodents Mammals><Self Administered><Self Administration><Severities><Source><Subgroup><Substance Use Disorder><Techniques><Translating><Treatment Protocols><Treatment Regimen><Treatment Schedule><Universities><Viral Burden><Viral Load><Viral Load result><Viral reservoir><Virus><Virus reservoir><Virus-HIV><addiction><addictive disorder><anti-retroviral><antiretroviral therapy><antiretroviral treatment><bloodbrain barrier><clinical translation><clinically translatable><developmental><drug/agent><gitter cell><human immunodeficiency virus cure><improved><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><mesoglia><microglial cell><microgliocyte><neural control><neural regulation><neurogenesis><neurological disease><neuromodulation><neuromodulatory><neuroregulation><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><perivascular glial cell><preclinical findings><preclinical information><prevent><preventing><programs><site targeted delivery><substance use and disorder><success><targeted delivery>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alejandro Benjamin Balazs

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

High-opportunity lead · 80/100
Likely hiring
Large award
Very recent
Active award
$1,052,100
FY 2026

Project Title

Polyclonal Bi-Specific Vectored ImmunoTherapy to Functionally Cure HIV Infection

Grant Number:

5DP1DA060607-03

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/15/2024

End Date:

3/31/2029

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Large budget suggests more room for personnel or project growth.
  • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary / Abstract This proposal describes the framework of a DP1 grant for Alejandro B. Balazs, PhD. Dr. Balazs is currently an assistant professor at Harvard Medical School and a principal investigator at the Ragon Institute of MGH, MIT & Harvard. Dr. Balazs' research is focused on engine...

Research Terms

<AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Animal Model><Animal Models and Related Studies><Anti-Retroviral Agents><Antibodies><Assay><Bioassay><Biological Assay><Cell Body><Cells><Communicable Diseases><Development><Doctor of Philosophy><Dose><Drugs><Engineering><Escape Mutant><Gene Transfer><Grant><HIV><HIV Infections><HIV cure><HIV functional cure><HIV individuals><HIV infected individuals><HIV infected persons><HIV intervention><HIV people><HIV positive individuals><HIV positive people><HIV replication><HIV therapeutic><HIV therapy><HIV treatment><HIV viral infection><HIV viral replication><HIV virus infection><HIV-1><HIV-1 cure><HIV-1 functional cure><HIV-1 infection><HIV-1 intervention><HIV-1 replication><HIV-1 therapeutic><HIV-1 therapy><HIV-1 treatment><HIV-1 viral replication><HIV-1 virus replication><HIV-I><HIV/AIDS cure><HIV1><Health><Human Immunodeficiency Virus Type 1><Human Immunodeficiency Virus therapy><Human Immunodeficiency Virus treatment><Human Immunodeficiency Virus-1><Human Immunodeficiency Viruses><Human immunodeficiency virus 1><Immune mediated therapy><Immune response><Immune system><Immunologically Directed Therapy><Immunotherapy><Individual><Infection><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Infectious Diseases><Infectious Disorder><LAV-HTLV-III><Laboratories><Lymphadenopathy-Associated Virus><Medication><Mice><Mice Mammals><Mission><Murine><Mus><NHP models><NIDA><NIH><National Institute of Drug Abuse><National Institute on Drug Abuse><National Institutes of Health><Outcome><PLWH><PWH><Persons><Ph.D.><PhD><Pharmaceutical Preparations><Principal Investigator><Regimen><Research><Series><Substance Use Disorder><Technology><Testing><Therapeutic Intervention><United States National Institutes of Health><Virus><Virus-HIV><anti-retroviral><design><designing><developmental><drug/agent><engineered immune system><experiment><experimental research><experimental study><experiments><host response><human immunodeficiency virus cure><human immunodeficiency virus infection><human immunodeficiency virus replication><human immunodeficiency virus-1 replication><immune engineering><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunoengineering><immunoresponse><improved><in vivo><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected with HIV><infected with human immunodeficiency virus><intervention therapy><medical college><medical schools><model of animal><new drug class><nonhuman primate models><novel><novel drug class><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><polyclonal antibody><professor><school of medicine><substance use and disorder><treat HIV><treat Human Immunodeficiency Virus><vector>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Baljit Khakh

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

High-opportunity lead · 80/100
Likely hiring
Large award
Very recent
Active award
$1,000,412
FY 2026

Project Title

Fundamental astrocyte biology in intact neural circuits

Grant Number:

5R35NS111583-08

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2019

End Date:

4/30/2027

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Large budget suggests more room for personnel or project growth.
  • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

A central goal of neurobiology is to understand how the brain forms, stores, retrieves, modifies and encodes information, and to determine how these operations go awry in neurological and psychiatric diseases. The focus of this application is astrocytes, a type of glia. Long considered simply the br...

Research Terms

<21+ years old><Abscission><Acquired brain injury><Adult><Adult Human><Astrocytes><Astrocytus><Astroglia><Autoregulation><Award><Basal Ganglia><Basal Nuclei><Biology><Blood Vessels><Brain><Brain Diseases><Brain Disorders><Brain Injuries><Brain Nervous System><CNS Nervous System><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Central Nervous System><Corpus Striatum><Corpus striatum structure><Data><Data Bases><Databases><Development><Disease><Disorder><Dysfunction><Encephalon><Encephalon Diseases><Environment><Evaluation><Excision><Exploratory/Developmental Grant for Diagnostic Cancer Imaging><Extirpation><Functional disorder><Glia><Glial Cells><Glues><Goals><Homeostasis><Intracellular Communication and Signaling><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Ions><Kolliker's reticulum><Laboratories><Maintenance><Mental disorders><Mental health disorders><Molecular><Nerve Cells><Nerve Transmitter Substances><Nerve Unit><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Transmission><Neuraxis><Neurobiology><Neurocyte><Neuroglia><Neuroglial Cells><Neurologic Disorders><Neurological Disorders><Neurons><Neurosciences><Neurotransmitters><Non-neuronal cell><Nonneuronal cell><Physicians><Physiologic><Physiological><Physiological Homeostasis><Physiopathology><Process><Psychiatric Disease><Psychiatric Disorder><R21 Award><Regulation><Removal><Research><Research Resources><Resources><Role><Scientist><Signal Transduction><Signal Transduction Systems><Signaling><Striate Body><Striatum><Surgical Removal><Synapses><Synaptic><Synaptic Transmission><Testing><Therapeutic><Training><Withdrawal><Work><adulthood><astrocytic glia><biological signal transduction><brain damage><brain-injured><data base><developmental><excitotoxic><excitotoxicity><in vivo><insight><mental illness><nerve cement><neural><neural circuit><neural circuitry><neuro-vascular coupling><neurobiological><neurocircuitry><neurological disease><neuronal><neurovascular coupling><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><operation><operations><pathophysiology><programs><psychiatric illness><psychological disorder><resection><social role><striatal><synapse><synapse formation><synaptic circuit><synaptic circuitry><synaptogenesis><tool><vascular>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KARSTEN GRONERT

UNIVERSITY OF CALIFORNIA BERKELEY, BERKELEY, CA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$624,743
FY 2026

Project Title

Function and Regulation of Constitutive Prostaglandin D2 and DP Receptor Signaling in Retinal Health and Neurodegeneration

Grant Number:

1R01EY036920-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2026

End Date:

4/30/2030

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Award size is strong enough to merit immediate review.
  • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Five distinct prostaglandins are essential lipid mediators and the non-selective inhibition of their formation is the mechanism of action for all NSAIDs. NSAIDs are a routine treatment for ocular allergies, pain, inflammation and macular edema. In sharp contrast, amplification of prostaglandin signa...

Research Terms

<Agonist><Allergy><Ammon Horn><Assay><Astrocytes><Astrocytus><Astroglia><Autoregulation><Axon><Bioassay><Biological Assay><Body Tissues><Cell Body><Cell Communication and Signaling><Cell Death Induction><Cell Signaling><Cells><Chronic><Common Rat Strains><Cornu Ammonis><Cranial Nerve II><Cre-Lox><Cre-LoxP><Cre/LoxP><Data><Dinoprostone><Down-Regulation><Dysfunction><Enzyme Gene><Enzymes><Eye><Eyeball><Functional disorder><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G-Protein-Coupled Receptors><GPCR><Generations><Genes><Glaucoma><Glutamates><Health><Hippocampus><Homeostasis><Hortega cell><Human><Immunoblotting><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><In Situ Hybridization><Inflammation><Inflammatory><Inner Nuclear Layer><Intracellular Communication and Signaling><Intraocular Pressure><KO mice><Kinases><Knock-out Mice><Knockout Mice><Knowledge><L-Glutamate><Maintenance><Marrow Mast Cell><Mice><Mice Mammals><Microglia><Modeling><Modern Man><Murine><Mus><NSAIDs><Nerve Cells><Nerve Degeneration><Nerve Unit><Neural Cell><Neurocyte><Neuron Degeneration><Neurons><Non-Steroidal Anti-Inflammatory Agents><Null Mouse><Ocular Hypertension><Ocular Tension><Optic Nerve><PGD2><PGE2><PGE2 alpha><PGE2alpha><Pain><Painful><Pathway interactions><Phosphotransferase Gene><Phosphotransferases><Physiologic><Physiologic Intraocular Pressure><Physiological><Physiological Homeostasis><Physiology><Physiopathology><Primates><Primates Mammals><Production><Prostaglandin D2><Prostaglandin E2><Prostaglandin E2 alpha><Prostaglandin E2alpha><Prostaglandin Inhibition><Prostaglandins><Prostanoids><RNA Seq><RNA sequencing><RNAseq><Rat><Rats Mammals><Rattus><Receptor Protein><Receptor Signaling><Regulation><Retina><Role><Second Cranial Nerve><Signal Transduction><Signal Transduction Systems><Signaling><Therapeutic><Tissue Basophils><Tissues><Toxic effect><Toxicities><Trabecular Meshwork><Trabecular meshwork structure><Transphosphorylases><Upregulation><Vascular Diseases><Vascular Disorder><Western Blotting><Western Immunoblotting><allergen response><allergic response><allergy response><astrocytic glia><biological signal transduction><blood vessel disorder><clinical relevance><clinically relevant><frontier><gangliocyte><ganglion cell><gene function><gitter cell><glaucomatous><glutamatergic><hippocampal><in situ Hybridization Genetics><in situ Hybridization Staining Method><interest><intra-ocular pressure><lipid mediator><lipidomics><loss of function><macroglia><macular edema><mast cell><mastocyte><mesoglia><microglial cell><microgliocyte><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neuronal><neuronal degeneration><neuroprotection><neuroprotective><non-human primate><non-steroidal anti-inflammatory drugs><nonhuman primate><novel><ocular hypertensive><pathophysiology><pathway><perivascular glial cell><protein blotting><receptor><response><scRNA sequencing><scRNA-seq><screening><screenings><selective expression><selectively expressed><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><therapeutic target><transcriptome sequencing><transcriptomic sequencing><vascular dysfunction><vasculopathy>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Gaurav Das Gaiha

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

High-opportunity lead · 72/100
Likely hiring
Large award
Recent
Active award
$1,169,000
FY 2026

Project Title

Harnessing Highly Networked HLA-E-Restricted CTL Epitopes to Achieve a Broadly Effective HIV Cure

Grant Number:

5DP1DA058476-04

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2023

End Date:

2/29/2028

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT This proposal describes the framework of an Avant-Garde DP1 award for Dr. Gaurav Gaiha M.D. D.Phil. Dr. Gaiha is currently an Assistant Professor of Medicine at Harvard Medical School, Massachusetts General Hospital and the Ragon Institute of MGH, Harvard and MIT. Dr. Gaiha’s research is fo...

Research Terms

<AIDS Vaccines><AIDS Virus><AIDS vaccine><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Adherence><Alleles><Allelomorphs><Animals><Antigenic Determinants><Antigens><Award><Binding Determinants><Cell-Mediated Lympholytic Cells><Cytolytic T-Cell><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><Data><Development><Doctor of Medicine><Epidemic><Epitopes><General Hospitals><Genes><HIV><HIV cure><HIV functional cure><HIV treatment vaccine><HIV vaccine><HIV vaccine therapy><HIV-1 cure><HIV-1 functional cure><HIV/AIDS Vaccines><HIV/AIDS cure><Human><Human Immunodeficiency Viruses><Individual><Knock-in><Knowledge><LAV-HTLV-III><Life><Lymphadenopathy-Associated Virus><M.D.><Massachusetts><Medicine><Methodology><Mice><Mice Mammals><Mission><Modern Man><Murine><Mus><NIDA><NIH><National Institute of Drug Abuse><National Institute on Drug Abuse><National Institutes of Health><Nature><Network Analysis><Pathway Analysis><Population><Proteome><Research><Structure><T cell response><T-Cell Epitopes><T-Lymphocyte Epitopes><Testing><Therapeutic><Translations><United States National Institutes of Health><Vaccines><Virus-HIV><Work><abused drug><abused drugs><developmental><drug abused><drug of abuse><drugs abused><drugs of abuse><human immunodeficiency virus cure><human immunodeficiency virus vaccine><immunogen><immunogenicity><innovate><innovation><innovative><killer T cell><knockin><medical college><medical schools><new vaccines><next generation vaccines><novel><novel vaccines><professor><protein structure><protein structures><proteins structure><rational design><resistance mutation><resistant mutation><school of medicine><theories><therapeutic HIV vaccination><therapeutic HIV vaccine><therapeutic vaccination against HIV><translation><vaccine against HIV><vaccine candidate>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alan David Levine

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,215,234
FY 2025

Project Title

CWRU Center for Excellence on the Impact of Substance Use on HIV

Grant Number:

5P30DA054557-05

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/15/2021

End Date:

5/31/2027

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary - Overview The newly developed CWRU (Case Western Reserve University) Center for Excellence on the Impact of Substance Use on HIV was conceived in August 2017 and was initiated to effectively promote excellence in basic, translational, and clinical research concerning the intersecti...

Research Terms

<3-D modeling><3D modeling><AIDS><AIDS Virus><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Affect><Award><Basic Research><Basic Science><Behavioral><Behavioral Research><Bioinformatics><Biological Mimetics><Biometrics><Biometry><Biomimetics><Biostatistics><Body Tissues><Brain><Brain Nervous System><Business-Friendly Atmosphere><Cannabis><Capital><Caring><Cell Body><Cell model><Cells><Cellular model><Cities><Clinic><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Cocaine misuse><Communities><Community Outreach><Complex><Computational Biology><County><Crystal Meth><Crystal methamphetamine><Data Bases><Databases><Deoxyephedrine><Desoxyephedrine><Development><Diagnosis><Discipline><Disease><Disorder><Drug usage><Dysfunction><Education><Educational aspects><Encephalon><Equipment><Exposure to><Faculty><Faculty Education><Faculty Training><Foundations><Functional disorder><Funding><Grant><HCV co-infection><HCV coinfection><HCV/HIV><HIV><HIV and HCV><HIV and hepatitis C><HIV associated neurological disease><HIV associated neurological disorder><HIV-HCV><HIV/HCV><HIV/Hepatitis C><Health><Hepatitis C co-infection><Hospitals><Human Immunodeficiency Viruses><IQ Deficit><Immune><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infrastructure><International><Investigation><Investigators><LAV-HTLV-III><Leadership><Link><Lymphadenopathy-Associated Virus><METH use><Medical Directors><Medical center><Medicine><Memory Deficit><Memory impairment><Mental Health><Mental Hygiene><Mentors><Methamphetamine><Methods><Methylamphetamine><Modeling><Molecular><Motivation><Mucosa><Mucosal Tissue><Mucous Membrane><Myelogenous><Myeloid><N-Methylamphetamine><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Neurocognitive Deficit><Neurologic><Neurologic outcome><Neurological><Neurological outcome><Opiates><Opioid><Outcome><Pathogenesis><Patient Recruitments><Patients><Persons><Physician Executives><Physiopathology><Position><Positioning Attribute><Prevention Research><Prevention education><Process><Progenitor Cells><Proteomics><Psychological Health><Public Health><Reporting><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Risk><Rural><Schools><Services><Social Sciences><Strategic Planning><Substance Use Disorder><Survey Instrument><Surveys><Systems Biology><THC co-use><THC use><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Technology><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Tissues><Translational Research><Translational Science><Trauma><Underserved Population><United States Department of Veterans Affairs><United States Veterans Administration><Universities><University Hospitals><Veterans Administration><Veterans Affairs><Victimization><Violence><Virus-HIV><behavior outcome><behavioral health intervention><behavioral outcome><biobank><biorepository><business-friendly environment><cannabis use><career><clinical database><co-morbid><co-morbidity><cocaine use><cohort><collaborative atmosphere><collaborative environment><comorbidity><computer biology><conference><convention><data base><design><designing><developmental><drug use><experience><faculty development><faculty professional development><gastrointestinal><hepatitis C coinfection><hepatitis C virus co-infection><hepatitis C virus coinfection><iPS><iPSC><iPSC technology><iPSCs><immune reconstitution><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><immunosuppressive response><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cell technology><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><insight><instructor training><intelligence quotient deficit><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary collaboration><interdisciplinary environment><lecturer><lipidomics><marijuana use><medical college><medical schools><memory dysfunction><metabolism measurement><metabolomics><metabonomics><meth><methamphetamine use><microbiome><neural inflammation><neuro-AIDS><neuro-HIV><neuroAIDS><neuroHIV><neurocognitive decline><neurocognitive impairment><neuroinflammation><neuroinflammatory><new technology><next generation><novel technologies><opiate consumption><opiate drug use><opiate intake><opiate use><opioid consumption><opioid drug use><opioid intake><opioid use><participant recruitment><pathophysiology><peer-group atmosphere><peer-group environment><prevent violence><programs><school of medicine><service intervention><sex risk behavior><sexual risk behavior><stem cells><substance misuse><substance use><substance use and disorder><substance using><suburb><suburban><suburbia><summit><symposia><symposium><synergism><teacher development><three-dimensional modeling><transcriptomics><transdisciplinary collaboration><translation research><translational investigation><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><violence prevention><violent><violent behavior>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KEVIN B. JOHNSON

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 60/100
Likely hiring
Large award
Active award
$1,137,500
FY 2025

Project Title

Helping Doctors Doctor: Using AI to Automate Documentation and "De-Autonomate" Health Care

Grant Number:

5DP1LM014558-03

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2023

End Date:

7/31/2028

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Large budget suggests more room for personnel or project growth.

Project Abstract

Johnson, Kevin DP1 Details Project Name: Helping Doctors Doctor: Using AI to Automate Documentation and “De-Autonomate” Health Care Project Summary Clinical encounter documentation is one of the most time-consuming tasks of the ambulatory encounter, taking approximately two hours for every hour spen...

Research Terms

<Algorithms><Area><Characteristics><Clinical><Communication><Computer Vision Systems><Consumption><Country><Data><Data Analytics><Decision Making><Diagnosis><Documentation><Electronic Health Record><Engineering><Gene Transcription><Generations><Genetic Transcription><Goals><Health Care><Hour><Image><Investigation><Jobs><Label><Learning><Length><Machine Learning><Manuals><Medical><Methods><Names><Natural Language Processing><Occupations><Patients><Pattern><Physicians><Process><Professional Positions><QOC><Quality of Care><RNA Expression><Source><System><Techniques><Technology><Testing><Time><Transcription><User-Computer Interface><Work><burn-out><burnout><child health care provider><clinical encounter><cognitive burden><cognitive load><computer science><computer scientist><computer vision><cost><data streams><deep learning><deep learning method><deep learning strategy><design><designing><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><human computer interface><human machine interface><imaging><implicit bias><improved><learning activity><learning method><learning strategies><learning strategy><machine based learning><man machine interface><multidisciplinary><name><named><naming><natural language understanding><novel><pediatric care provider><pediatric health care provider><pediatric provider><pediatrician><skills><supervised learning><supervised machine learning><unsupervised learning><unsupervised machine learning>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ijeoma Opara

YALE UNIVERSITY, NEW HAVEN, CT

Good lead · 50/100
Likely hiring
Large award
$1,172,500
FY 2024

Project Title

Integrating Community Based Participatory Research and Machine Learning Methods to Predict Youth Substance Use Disorders for Urban Cities in New Jersey

Grant Number:

5DP1DA058982-02

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2023

End Date:

6/30/2025

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary My lab uses a community-based participatory research approach to reduce health disparities in substance use among Black and Hispanic youth in urban communities. We primarily work in New Jersey (NJ) due to our close ties with Paterson and East Orange, NJ which both have the highest n...

Research Terms

<Asthma><Award><Behavior><Black><Black race><Bronchial Asthma><Characteristics><Cities><Communities><Complex><Data><Data Set><Decrease health disparities><Development><Epidemic><Equation><Equity><Health><Health disparity mitigation><Health disparity reduction><Hispanic><Individual><Investigators><Learning><Lower health disparities><Machine Learning><Methods><Mitigate health disparities><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Neighborhoods><New Jersey><Oranges><Outcome><Prevention><Prevention Research><Process><Racial Equity><Reduce health disparities><Research Design><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Factors><Role><Scientist><Statistical Methods><Statistical Study><Study Type><Substance Use Disorder><System><Urban Community><Work><Youth><Youth 10-21><addiction><addictive disorder><adolescent substance use><behavior change><children of color><community based participatory research><community engagement><community led research><community participatory research><community partnered participatory research><developmental><engagement with communities><ethnic minority><health equity><innovate><innovation><innovative><machine based learning><machine learning based method><machine learning method><machine learning methodologies><marginalization><member><model development><model developments><novel><participatory action research><prediction algorithm><prevent substance misuse><prevent substance use><protective factors><race bias><racial bias><racial minority group><racial minority individual><racial minority people><racial minority population><respiratory><social health determinants><social role><statistic methods><study design><substance misuse prevention><substance use><substance use among adolescents><substance use among youth><substance use and disorder><substance use prevention><substance using><youth of color><youth substance use>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Hongjie Dai

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 50/100
Likely hiring
Large award
$1,099,000
FY 2022

Project Title

Human Infrared Vision at Molecular and Cellular Scale

Grant Number:

5DP1NS105737-05

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2017

End Date:

8/31/2023

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract. A fundamental problem this DP1 project will address is the inability of imaging at single molecular or cellular level deep in a living body (animal or human). I plan to enable in vivo ‘molecular infrared vision’ that detects deep-near-infrared fluorescence for peering into ...

Research Terms

<3-D><3-Dimensional><3D><Acquired brain injury><Address><Animal Model><Animal Models and Related Studies><Animals><Apoplexy><Area><Basic Research><Basic Science><Biological><Biological Function><Biological Process><Biology><Blood flow><Body Tissues><Brain><Brain Injuries><Brain Nervous System><Brain Trauma><Brain Vascular Accident><Cancers><Cardiovascular Diseases><Cell Body><Cells><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chemicals><Chemistry><Clinic><Clinical><Craniotomy><Encephalon><Fluorescence><Glean><Human><Image><Image-Guided Surgery><Intervention><Intervention Strategies><Investigation><Malignant Neoplasms><Malignant Tumor><Medicine><Mice><Mice Mammals><Modern Man><Molecular><Murine><Mus><NIR imaging><NIR optical imaging><Near-infrared Fluorescence Imaging><Near-infrared optical imaging><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurons><Neurosciences><Physics><Process><Resolution><Sentinel Lymph Node Mapping><Sight><Skull><Specificity><Stimulus><Stroke><Structure><Time><Tissue imaging><Tissues><Translations><Traumatic Brain Injury><Tumor Cell><Vision><Work><animal tissue><base><biologic><brain attack><brain damage><brain-injured><cancer imaging><cardiovascular disorder><cerebral vascular accident><cerebrovascular accident><chemical synthesis><cranium><disease diagnostic><fluorescence imaging><fluorescent imaging><fluorophore><image guidance><image guided><image-based method><imaging><imaging method><imaging modality><in vivo><innovate><innovation><innovative><instrumentation><interventional strategy><intra-operative imaging><intraoperative imaging><malignancy><materials science><model of animal><model organism><molecular imaging><molecule imaging><movie><nano materials><nano science><nanomaterials><nanoscience><near infrared imaging><neoplasm/cancer><neoplastic cell><neuronal><novel><oncologic imaging><oncology imaging><optic imaging><optical imaging><peer><repair><repaired><single molecule><skull incision><stem cell based therapy><stem cell mediated therapy><stem cell therapeutics><stem cell therapy><stem cell treatment><stem cell-based treatment><surgical imaging><three dimensional><traumatic brain damage><treatment effect><tumor><tumor imaging><visual function>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Neal L Weintraub

AUGUSTA UNIVERSITY, AUGUSTA, GA

Exploratory lead · 44/100
Likely hiring
Above-average budget
$527,553
FY 2021

Project Title

Mechanisms of myeloperoxidase and Nox4 interactions in abdominal aortic aneurysm

Grant Number:

5R01HL142097-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2018

End Date:

10/31/2022

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.
  • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Abdominal aortic aneurysm (AAA) disease is a frequent cause of morbidity and mortality. Roughly 25,000 AAA repairs are performed each year, and AAAs account for over 13,000 deaths annually in the United States. The underlying mechanisms of AAA formation are unknown, which has hampere...

Research Terms

<3-Pyridinecarboxylic Acid><Abdominal Aortic Aneurysm><Address><Agonist><Alleles><Allelomorphs><Aneurysm><AngII><Angiotensin II><Animal Model><Animal Models and Related Studies><Aorta><Aortic Aneurysm><Assay><Bioassay><Biologic Assays><Biological Assay><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Blood Vessels><Blood leukocyte><Blood monocyte><Body Tissues><Calcium Chloride><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell Surface Receptors><Cells><Cessation of life><Coupled><D2 receptor><DRD2 Receptor><Data><Death><Deterioration><Development><Disease><Disorder><Dopamine D2 Receptor><Drug Targeting><Drugs><Enzyme Gene><Enzymes><Genetic><H2O2><Hematopoietic><Hemi-Myeloperoxidase><Heterozygote><Human><Hydrogen Peroxide><Hydroperoxide><In Vitro><Inflammation><Inflammatory><Infusion><Infusion procedures><Intracellular Communication and Signaling><KO mice><Knock-out Mice><Knockout Mice><Knowledge><Leiomyocyte><Leukocytes><Leukocytes Reticuloendothelial System><Link><Lipids><Lung><Lung Respiratory System><Marrow Neutrophil><Marrow leukocyte><Marrow monocyte><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Mediating><Medical><Medication><Mice><Mice Mammals><Modern Man><Morbidity><Morbidity - disease rate><Murine><Mus><Myeloperoxidase><Mφ><Neutrophil Activation><Neutrophil Infiltration><Neutrophil Recruitment><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Niacin><Nicotinic Acids><Null Mouse><Output><Oxidants><Oxidative Stress><Oxidizing Agents><PGD2><Pathogenesis><Patients><Peroxidases><Pharmaceutic Preparations><Pharmaceutical Preparations><Pharmacology><Play><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Prostaglandin D2><Proteins><Receptor Cell><Receptor Protein><Risk Factors><Role><Rupture><Ruptured Aortic Aneurysms><Signal Transduction><Signal Transduction Systems><Signaling><Site><Smoking><Smooth Muscle Cells><Smooth Muscle Myocytes><Smooth Muscle Tissue Cell><Source><Structure><Testing><Therapeutic><Tissues><United States><White Blood Cells><White Cell><aorta aneurysm><biological signal transduction><developmental><drug/agent><electron acceptor><experiment><experimental research><experimental study><hemopoietic><heterozygosity><improved outcome><in vivo><inhibitor><inhibitor/antagonist><macrophage><model of animal><model organism><monocyte><mortality><neutrophil><novel><overexpress><overexpression><prevent><preventing><pulmonary><receptor><recruit><repair><repaired><social role><therapeutic outcome><therapeutically effective><therapy outcome><uptake><vascular><white blood cell><white blood corpuscle>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alan David Levine

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$79,015
FY 2023

Project Title

CWRU Center for Excellence on the Impact of Substance Use on HIV

Grant Number:

3P30DA054557-03S1

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/15/2021

End Date:

5/31/2026

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary - Overview The newly developed CWRU (Case Western Reserve University) Center for Excellence on the Impact of Substance Use on HIV was conceived in August 2017 and was initiated to effectively promote excellence in basic, translational, and clinical research concerning the intersecti...

Research Terms

<3-D modeling><3D modeling><AIDS><AIDS Virus><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immuno-Deficiency Syndrome><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Acquired Immunologic Deficiency Syndrome><Affect><Award><Basic Research><Basic Science><Behavioral><Behavioral Research><Bio-Informatics><Bioinformatics><Biological Mimetics><Biometrics><Biometry><Biomimetics><Biostatistics><Body Tissues><Brain><Brain Nervous System><Business-Friendly Atmosphere><Cannabis><Capital><Caring><Cell Body><Cell model><Cells><Cellular model><Cities><Clinic><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Cocaine misuse><Communities><Community Outreach><Complex><Computational Biology><County><Crystal Meth><Crystal methamphetamine><Data Bases><Databases><Deoxyephedrine><Desoxyephedrine><Development><Diagnosis><Discipline><Disease><Disorder><Drug usage><Dysfunction><Education><Educational aspects><Encephalon><Equipment><Exposure to><Faculty><Faculty Education><Faculty Training><Foundations><Functional disorder><Funding><Grant><HCV co-infection><HCV coinfection><HCV/HIV><HIV><HIV and HCV><HIV and hepatitis C><HIV associated neurological disease><HIV associated neurological disorder><HIV-HCV><HIV/HCV><HIV/Hepatitis C><Health><Hepatitis C co-infection><Hospitals><Human Immunodeficiency Viruses><IQ Deficit><Immune><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infrastructure><International><Investigation><Investigators><LAV-HTLV-III><Leadership><Link><Lymphadenopathy-Associated Virus><METH use><Medical Directors><Medical center><Medicine><Memory Deficit><Memory impairment><Mental Health><Mental Hygiene><Mentors><Methamphetamine><Methods><Methylamphetamine><Modeling><Molecular><Motivation><Mucosa><Mucosal Tissue><Mucous Membrane><Myelogenous><Myeloid><N-Methylamphetamine><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Neurocognitive Deficit><Neurologic><Neurologic outcome><Neurological><Neurological outcome><Opiates><Opioid><Outcome><Pathogenesis><Patient Recruitments><Patients><Persons><Physician Executives><Physiopathology><Position><Positioning Attribute><Prevention Research><Prevention education><Process><Progenitor Cells><Proteomics><Psychological Health><Public Health><Reporting><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Risk><Rural><Schools><Services><Social Sciences><Strategic Planning><Substance Use Disorder><Survey Instrument><Surveys><Systems Biology><THC co-use><THC use><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Technology><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Tissues><Translational Research><Translational Science><Trauma><Underserved Population><United States Department of Veterans Affairs><United States Veterans Administration><Universities><University Hospitals><Veterans Administration><Veterans Affairs><Victimization><Violence><Virus-HIV><behavior outcome><behavioral health intervention><behavioral outcome><biobank><biorepository><business-friendly environment><cannabis use><career><clinical database><co-morbid><co-morbidity><cocaine use><cohort><collaborative atmosphere><collaborative environment><comorbidity><computer biology><conference><convention><data base><design><designing><developmental><drug use><experience><faculty development><faculty professional development><gastrointestinal><hepatitis C coinfection><hepatitis C virus co-infection><hepatitis C virus coinfection><iPS><iPSC><iPSC technology><iPSCs><immune reconstitution><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><immunosuppressive response><induced pluripotent cell><induced pluripotent stem cell><induced pluripotent stem cell technology><inducible pluripotent stem cell><innovate><innovation><innovative><insight><instructor training><intelligence quotient deficit><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary collaboration><interdisciplinary environment><lecturer><lipidomics><marijuana use><medical college><medical schools><memory dysfunction><metabolism measurement><metabolomics><metabonomics><meth><methamphetamine use><microbiome><neural inflammation><neuro-AIDS><neuro-HIV><neuroAIDS><neuroHIV><neurocognitive decline><neurocognitive impairment><neuroinflammation><neuroinflammatory><new technology><next generation><novel technologies><opiate consumption><opiate drug use><opiate intake><opiate use><opioid consumption><opioid drug use><opioid intake><opioid use><participant recruitment><pathophysiology><peer-group atmosphere><peer-group environment><prevent violence><programs><school of medicine><service intervention><sex risk behavior><sexual risk behavior><stem cells><substance misuse><substance use><substance use and disorder><substance using><suburb><suburban><suburbia><summit><symposia><symposium><synergism><teacher development><three-dimensional modeling><transcriptomics><transdisciplinary collaboration><translation research><translational investigation><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><violence prevention><violent><violent behavior>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Alan David Levine

CASE WESTERN RESERVE UNIVERSITY, CLEVELAND, OH

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$79,015
FY 2022

Project Title

CWRU Center for Excellence on the Impact of Substance Use on HIV

Grant Number:

3P30DA054557-02S1

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/15/2021

End Date:

5/31/2026

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary - Overview The newly developed CWRU (Case Western Reserve University) Center for Excellence on the Impact of Substance Use on HIV was conceived in August 2017 and was initiated to effectively promote excellence in basic, translational, and clinical research concerning the intersecti...

Research Terms

<3-D modeling><3D modeling><AIDS><AIDS Virus><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immuno-Deficiency Syndrome><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Acquired Immunologic Deficiency Syndrome><Affect><Award><Basic Research><Basic Science><Behavioral><Behavioral Research><Bio-Informatics><Bioinformatics><Biological Mimetics><Biometrics><Biometry><Biomimetics><Biostatistics><Body Tissues><Brain><Brain Nervous System><Business-Friendly Atmosphere><Cannabis><Capital><Caring><Cell Body><Cell model><Cells><Cellular model><Cities><Clinic><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Cocaine misuse><Communities><Community Outreach><Complex><Computational Biology><County><Crystal Meth><Crystal methamphetamine><Data Bases><Databases><Deoxyephedrine><Desoxyephedrine><Development><Diagnosis><Discipline><Disease><Disorder><Drug usage><Dysfunction><Encephalon><Equipment><Exposure to><Faculty><Faculty Education><Faculty Training><Foundations><Functional disorder><Funding><Grant><HCV co-infection><HCV coinfection><HCV/HIV><HIV><HIV and HCV><HIV and hepatitis C><HIV associated neurological disease><HIV associated neurological disorder><HIV-HCV><HIV/HCV><HIV/Hepatitis C><Health><Hepatitis C co-infection><Hospitals><Human Immunodeficiency Viruses><IQ Deficit><Immune><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Individual><Infrastructure><International><Investigation><Investigators><LAV-HTLV-III><Leadership><Link><Lymphadenopathy-Associated Virus><METH use><Medical Directors><Medical center><Medicine><Memory Deficit><Memory impairment><Mental Health><Mental Hygiene><Mentors><Methamphetamine><Methods><Methylamphetamine><Modeling><Molecular><Motivation><Mucosa><Mucosal Tissue><Mucous Membrane><Myelogenous><Myeloid><N-Methylamphetamine><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Neurocognitive Deficit><Neurologic><Neurologic outcome><Neurological><Neurological outcome><Opiates><Opioid><Outcome><Pathogenesis><Patient Recruitments><Patients><Persons><Physician Executives><Physiopathology><Position><Positioning Attribute><Prevention Research><Prevention education><Process><Progenitor Cells><Proteomics><Psychological Health><Public Health><Reporting><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Risk><Rural><Schools><Services><Social Sciences><Strategic Planning><Substance Use Disorder><Survey Instrument><Surveys><Systems Biology><THC co-use><THC use><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Technology><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Tissues><Translational Research><Translational Science><Trauma><Underserved Population><United States Department of Veterans Affairs><United States Veterans Administration><Universities><University Hospitals><Veterans Administration><Veterans Affairs><Virus-HIV><base><behavior outcome><behavioral health intervention><behavioral outcome><biobank><biorepository><business-friendly environment><cannabis use><career><clinical database><co-morbid><co-morbidity><cocaine use><cohort><collaborative atmosphere><collaborative environment><comorbidity><computer biology><conference><convention><data base><design><designing><developmental><drug use><experience><faculty development><faculty professional development><gastrointestinal><hepatitis C coinfection><hepatitis C virus co-infection><hepatitis C virus coinfection><iPS><iPSC><iPSC technology><iPSCs><immune reconstitution><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><induced pluripotent stem cell><induced pluripotent stem cell technology><inducible pluripotent stem cell><innovate><innovation><innovative><insight><instructor training><intelligence quotient deficit><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary collaboration><interdisciplinary environment><lecturer><lipidomics><marijuana use><medical college><medical schools><memory dysfunction><metabolism measurement><metabolomics><metabonomics><methamphetamine use><microbiome><neuro-AIDS><neuro-HIV><neuroAIDS><neuroHIV><neurocognitive decline><neurocognitive impairment><neuroinflammation><neuroinflammatory><new technology><next generation><novel technologies><opiate consumption><opiate drug use><opiate intake><opiate use><opioid consumption><opioid drug use><opioid intake><opioid use><participant recruitment><pathophysiology><peer-group atmosphere><peer-group environment><prevent violence><programs><school of medicine><service intervention><sex risk behavior><sexual risk behavior><stem cells><substance misuse><substance use><substance using><suburb><suburban><suburbia><summit><symposia><symposium><synergism><teacher development><three-dimensional modeling><transcriptomics><transdisciplinary collaboration><translation research><under served group><under served people><under served population><underserved group><underserved people><violence prevention><violence victimization>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Igor J. Koralnik

NORTHWESTERN UNIVERSITY AT CHICAGO, CHICAGO, IL

Exploratory lead · 36/100
Likely hiring
Solid budget
$327,396
FY 2021

Project Title

Contribution of the Virome to Alzheimer's pathogenesis

Grant Number:

3DP1DA048493-04S1

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/14/2020

End Date:

5/31/2024

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Alzheimer’s disease (AD) is a widespread age-related dementia of unknown etiology characterized by neuronal loss, atrophy, and aggregation of beta amyloid (neuritic plaques) and microtubule associated tau proteins (neurofibrillary tangles) in the brain. The major gap in our knowledge is what trigger...

Research Terms

<21+ years old><AD dementia><Abeta synthesis><Ablation><Adeno-Associated Viruses><Adult><Adult Human><Aging><Alzheimer><Alzheimer Type Dementia><Alzheimer disease><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's brain><Alzheimer's disease brain><Alzheimer's disease dementia><Alzheimer's disease patient><Alzheimer's patient><Alzheimers Dementia><Alzheimers disease><Amentia><Ammon Horn><Amyloid Plaques><Amyloid β production><Amyloid β synthesis><Atrophic><Atrophy><Attenuated><Autopsy><Aβ production><Aβ synthesis><Brain><Brain Nervous System><Causality><Cerebral cortex><Clinical><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Cornu Ammonis><Data><Dementia><Dependoparvovirus><Dependovirus><Deposit><Deposition><Detection><Development><Diagnostic><Disease><Disorder><Disturbance in cognition><Encephalon><Etiology><Exhibits><Experimental Animal Model><Family><Genetic Materials><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Susceptibility><Goals><Grant><HBLV><HHV-6><HHV6><HSV-1><HSV1><Herpes Simplex><Herpes Simplex Infections><Herpes Simplex Virus 1><Herpes Simplex Virus Type 1><Herpes simplex disease><Herpesviridae><Herpesvirus 1><Herpesvirus hominis disease><Herpesviruses><Hippocampus><Hippocampus (Brain)><Human><Human B-Lymphotropic Virus><Human Herpesvirus 6><Immune><Immune system><Immunes><Impaired cognition><In Situ Hybridization><Individual><Infection><Infectious Agent><Inflammatory><Inherited Predisposition><Inherited Susceptibility><Knowledge><MAPT gene><MAPT protein><MT-bound tau><MTBT1><Mice><Mice Mammals><Mission><Modern Man><Murine><Mus><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Nerve Cells><Nerve Unit><Neural Cell><Neuritic Plaques><Neurocyte><Neurofibrillary Tangles><Neurons><Parents><Pathogenesis><Pathologic><Patients><Pilot Projects><Play><Primary Senile Degenerative Dementia><Process><Proteins><Public Health><Reaction><Recombinant adeno-associated virus><Recombinant adeno-associated virus (rAAV)><Recurrence><Recurrent><Reporting><Research><Risk Factors><Role><Senile Plaques><Severities><Staging><Testing><Therapeutic Intervention><Tissue Sample><Variant><Variation><Viral><Viral Diseases><Viral Genetics><Viral Genome><Virus><Virus Diseases><Virus-HHV6><Work><abeta accumulation><abeta aggregation><abeta production><adeno associated virus group><adult neurogenesis><adulthood><age dependent><age related><aged><allergic/immunologic body system><allergic/immunologic organ system><amyloid beta accumulation><amyloid beta aggregation><amyloid beta plaque><amyloid beta production><amyloid beta synthesis><amyloid β accumulation><amyloid β aggregation><amyloid-b plaque><aβ accumulation><aβ aggregation><aβ plaques><burden of disease><burden of illness><causation><cognitive dysfunction><cognitive loss><cored plaque><deep sequencing><dementia of the Alzheimer type><developmental><diffuse plaque><disease burden><disease causation><experiment><experimental research><experimental study><genetic etiology><genetic mechanism of disease><genetic vulnerability><genetically predisposed><herpes simplex i><herpes virus><hippocampal><human disease><improved><in situ Hybridization Genetics><in situ Hybridization Staining Method><infectious organism><insoluble aggregate><intervention therapy><member><microtubule associated protein tau><microtubule bound tau><microtubule-associated protein tau><microtubule-bound tau><necropsy><nerve cell death><nerve cell loss><neurofibrillary degeneration><neurofibrillary lesion><neurofibrillary pathology><neurogenesis><neuron cell death><neuron cell loss><neuron death><neuron loss><neuronal><neuronal cell death><neuronal cell loss><neuronal death><neuronal loss><pathogenic virus><pilot study><postmortem><primary degenerative dementia><protein aggregate><protein aggregation><rAAV><recombinant AAV><senile dementia of the Alzheimer type><sequencing platform><social role><tangle><tau><tau Proteins><tau factor><viral infection><viral microbiome><viral pathogen><virome><virus genetics><virus genome><virus infection><virus pathogen><virus-induced disease><years of life lost to disability><years of life lost to disease><τ Proteins>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stanley Perlman

UNIVERSITY OF IOWA, IOWA CITY, IA

Exploratory lead · 36/100
Likely hiring
Solid budget
$326,546
FY 2021

Project Title

Role of microglia in MHV-induced demyelination

Grant Number:

5R01NS036592-23

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/1997

End Date:

1/31/2023

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.

Project Abstract

C57BL/6 mice infected with the neurotropic rJ2.2 variant of the JHM strain of mouse hepatitis virus (rJ2.2) develop acute and chronic demyelinating encephalomyelitis and thereby serve as a useful model for the human disease multiple sclerosis. The overall objective of this project has been to unders...

Research Terms

<Acute><Acute Disease><Address><Affect><After Care><After-Treatment><Aftercare><Apoptotic><Area><Autoregulation><Beta Proprotein Interleukin 1><Body Tissues><Brain><Brain Inflammation><Brain Nervous System><C57BL/6 Mouse><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cellular Immune Function><Central Nervous System Viral Diseases><Central Nervous System Viral Infections><Chronic><Defect><Demyelinating Diseases><Demyelinating Disorders><Demyelinations><Disease><Disorder><Disseminated Sclerosis><Drugs><Eicosanoids><Encephalitis><Encephalomyelitis><Encephalon><Funding><Gene Expression><Goals><Homeostasis><Homologous Protein><Hortega cell><Human><IFN><IL-1 beta><IL-1 β><IL-1-b><IL-1β><IL1-Beta><IL1-β><IL1B Protein><IL1F2><IL1β><Immune Surveillance><Immune response><Immunologic Surveillance><Immunologic Surveillances><Immunological Surveillance><Immunological Surveillances><Immunological response><Immunosurveillance><Infection><Inflammasome><Inflammation><Innate Immune Response><Interferons><Interleukin 1beta><Interleukin-1 beta><Interleukin-1β><Intracellular Communication and Signaling><Investigation><JHM strain><Laboratories><MHV-JHM><Maintenance><Mediating><Medication><Mice><Mice Mammals><Microglia><Modeling><Modern Man><Monitor><Mouse Hepatitis Virus><Mouse Strains><Multiple Sclerosis><Murine><Murine Gastroenteritis Virus><Murine hepatitis virus><Mus><Myelin><Myeloencephalitis><Myeloid Cells><Mφ><Neurologic><Neurological><Outcome><PGD2><Pathogenesis><Pathogenicity><Peptide Domain><Pharmaceutic Preparations><Pharmaceutical Preparations><Phenotype><Physiological Homeostasis><Play><Preinterleukin 1 Beta><Process><Prostaglandin D2><Prostaglandins><Prostanoids><Protein Domains><Protein Homolog><ProteinHomolog><Proteins><Receptor Protein><Regulatory T-Lymphocyte><Research><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><T cell response><T4 Cells><T4 Lymphocytes><Teff cell><Tertiary Protein Structure><Time><Tissues><Treg><Up-Regulation><Upregulation><Variant><Variation><Viral><Viral CNS Infections><Viral Diseases><Viral Encephalitis><Viral Infectious Encephalomyelitis><Viral Pathogenesis><Virus><Virus Diseases><Work><acute disease/disorder><acute disorder><adaptive immune response><biological signal transduction><drug/agent><effector T cell><gitter cell><host response><human disease><immune function><immune system response><immunoresponse><improved outcome><insular sclerosis><macrophage><mesoglia><microglial cell><microgliocyte><mouse hepatitis virus JHM><neurotropic><neurotropic virus><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><perivascular glial cell><post treatment><receptor><regulatory T-cells><response><social role><viral infection><virus host interaction><virus infection><virus pathogenesis><virus-induced disease>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kafui Dzirasa

DUKE UNIVERSITY, DURHAM, NC

Exploratory lead · 36/100
Likely hiring
Active award
$14,191
FY 2024

Project Title

Precision editing of neural circuits using engineered electrical synapses

Grant Number:

3DP1MH132709-02S1

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/8/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Abstract of funded grant DP1 (5DP1MH132709). Precision editing of neural circuits using engineered electrical synapses Pioneering approaches including optogenetics and designer receptors exclusively activated by designer drugs (DREADDs) enable the direct modulation of the activity of individual gene...

Research Terms

<Address><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Animal Model><Animal Models and Related Studies><Anxiety><Assay><Behavior><Bioassay><Biological Assay><Brain><Brain Nervous System><Calcium><Cell Body><Cells><Communicating Junction><Connexins><DREADDs><Docking><Electrical Engineering><Electrical Synapse><Emotional><Emotions><Encephalon><Engineering><Evoked Potentials><Exhibits><Fear><Fluorescence><Fright><Funding><Future><Gap Junction Proteins><Gap Junctions><Grant><Individual><Light><Low-resistance Junction><Measures><Mental Depression><Mental disorders><Mental health disorders><Methods><Mice><Mice Mammals><Murine><Mus><Nexus Junction><Optics><Photoradiation><Physiology><Pre-Clinical Model><Preclinical Models><Property><Proteins><Psychiatric Disease><Psychiatric Disorder><Rapid screening><Research><Rhodopsin><Synapses><Synaptic><System><Testing><Transfection><Viral><Virus><Visual Purple><addiction><addictive disorder><amygdaloid nuclear complex><brain cell><calcium flux><calcium mobilization><cell type><conditioned fear><depression><designer receptors exclusively activated by designer drugs><electrical potential><emotional behavior><experiment><experimental research><experimental study><experiments><fear conditioning><high risk><member><mental illness><model of animal><model organism><multi-electrode arrays><multielectrode arrays><mutant><neural circuit><neural circuitry><neural control><neural regulation><neurocircuitry><neuromodulation><neuromodulatory><neuroregulation><new approaches><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel approaches><novel strategies><novel strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><optical><optogenetics><prevent><preventing><psychiatric illness><psychological disorder><release of sequestered calcium ion into cytoplasm><synapse><synaptic circuit><synaptic circuitry><tool><translation to humans>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Michelle Monje-Deisseroth

STANFORD UNIVERSITY, STANFORD, CA

Exploratory lead · 26/100
Likely hiring
$56,720
FY 2021

Project Title

Glioma Circuitry: Bridging Systems Neuroscience and Cancer

Grant Number:

3DP1NS111132-03S1

Activity Code:

DP1

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/15/2021

End Date:

12/31/2022

Why this may be worth a closer look

  • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary DP1 NS111132 original summary: High-grade gliomas such as glioblastoma and diffuse intrinsic pontine glioma (DIPG) are among the most intractable human cancers. These tumors are quick to recur and nearly impossible to eliminate, and as such represent the leading cause brain cancer-re...

Research Terms

<0-11 years old><21+ years old><Adult><Adult Human><Astrocytes><Astrocytus><Astroglia><Brain><Brain Cancer><Brain Nervous System><Cancer Biology><Cancers><Cell Body><Cell Communication and Signaling><Cell Growth in Number><Cell Multiplication><Cell Proliferation><Cell Signaling><Cell Survival><Cell Viability><Cells><Cellular Proliferation><Cessation of life><Child><Child Youth><Children (0-21)><Communicating Junction><DIPG><Death><Dependence><Diffuse intrinsic pontine glioma><Electrophysiology><Electrophysiology (science)><Encephalon><Gap Junctions><Glial Cell Tumors><Glial Neoplasm><Glial Tumor><Glioblastoma><Glioma><Grade IV Astrocytic Neoplasm><Grade IV Astrocytic Tumor><Grade IV Astrocytoma><Growth Agents><Growth Factor><Growth Substances><Human><Intracellular Communication and Signaling><Low-resistance Junction><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Brain><Malignant neoplasm of brain><Mediating><Membrane><Modern Man><Molecular><Nature><Nerve Cells><Nerve Unit><Nervous System><Nervous system structure><Neural Cell><Neurocyte><Neuroglial Neoplasm><Neuroglial Tumor><Neurologic Body System><Neurologic Organ System><Neurons><Neurophysiology / Electrophysiology><Neurosciences><Nexus><Nexus Junction><Pattern><Proteins Growth Factors><Research><Resistance><Signal Transduction><Signal Transduction Systems><Signaling><Structure><Synapses><Synaptic><System><Work><adulthood><astrocytic glia><biological signal transduction><cancer microenvironment><effective therapy><effective treatment><electrophysiological><glial-derived tumor><glioblastoma multiforme><malignancy><membrane structure><neoplasm/cancer><neural circuit><neural circuitry><neurocircuitry><neuroglia neoplasm><neuroglia tumor><neuronal><neuronal circuit><neuronal circuitry><release factor><resistant><response><spongioblastoma multiforme><synapse><synaptic circuit><synaptic circuitry><tumor><tumor microenvironment><youngster>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Audra Iness

VIRGINIA COMMONWEALTH UNIVERSITY, RICHMOND, VA

Exploratory lead · 18/100
Training-friendly
$10,585
FY 2021

Project Title

Mechanisms of B-Myb oncogenicity in ovarian cancer

Grant Number:

5F30CA221004-04

Activity Code:

F30

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

4/1/2018

End Date:

4/30/2021

Why this may be worth a closer look

  • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary-Abstract B-Myb is an oncoprotein involved in cell cycle gene regulation. B-Myb contacts the MuvB core of five proteins (LIN9, LIN37, LIN52, LIN53/RBBP4, and LIN54) to form the MMB (Myb-MuvB) complex. The MMB complex, in turn, promotes expression of late cell cycle genes for progress...

Research Terms

<ATP-protein phosphotransferase><Assay><B-MYB><B-MYB Protein><BMYB><BMYB Gene Product><Basal Transcription Factor><Basal transcription factor genes><Binding><Binding Sites><Bio-Informatics><Bioassay><Bioinformatics><Biologic Assays><Biological Assay><Biological Markers><Cancers><Cell Body><Cell Communication and Signaling><Cell Cycle><Cell Cycle Arrest><Cell Cycle Deregulation><Cell Cycle Genes><Cell Cycle Progression><Cell Division Cycle><Cell Division Cycle Genes><Cell Growth in Number><Cell Multiplication><Cell Proliferation><Cell Signaling><Cells><Cellular Proliferation><Clinical><Combining Site><Complex><Cues><Cyclin-Dependent Kinases><Cyclin-Dependent Protein Kinases><Data><Disease><Disorder><Dreams><Epithelial Cells><Equilibrium><Evaluation><Fallopian Tubes><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Future><Gene Action Regulation><Gene Copy Number><Gene Dosage><Gene Expression><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><General Transcription Factor Gene><General Transcription Factors><Generalized Growth><Genes><Genetic><Genetic Alteration><Genetic Change><Genetic defect><Goals><Growth><Health><Human><IRB><IRBs><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><In Vitro><Institutional Review Boards><Intracellular Communication and Signaling><Kinase Family Gene><L-Serine><Link><M Phase><MGC15600><MYB-Related Protein B><MYBL2><MYBL2 gene><Malignant Cell><Malignant Neoplasms><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Tumor><Malignant Tumor of the Ovary><Malignant neoplasm of ovary><Mammalian Cell><Mammalian Oviducts><Measures><Mediating><Mitosis><Mitosis Stage><Modeling><Modern Man><Molecular Interaction><Molecular Marker of Prognosis><Mutation><Oncogene Products><Oncogene Proteins><Oncogenic><Oncoproteins><Outcome><Ovarian Serous Adenocarcinoma><Ovarian Serous Carcinoma><Ovary Cancer><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Phenotype><Play><Position><Positioning Attribute><Prognosis><Prognosis Marker><Prognostic Marker><Proliferating><Protein Kinase><Proteins><Protocol><Protocols documentation><Reactive Site><Recurrence><Recurrent><Regulator Genes><Repression><Role><S Period><S Phase><SKOV3><SKOV3 cells><Salpinx><Serine><Serous Adenocarcinoma of the Ovary><Serous Carcinoma of the Ovary><Signal Transduction><Signal Transduction Systems><Signaling><SkOV-3><Synthesis Period><Synthesis Phase><System><TCGA><Testing><Tet><Tetanus Helper Peptide><The Cancer Genome Atlas><Tissue Growth><Tissue Sample><Transcription Factor Proto-Oncogene><Transcription factor genes><Transcriptional Regulatory Elements><Treatment outcome><Tumor Tissue><Uterine Tubes><Work><balance><balance function><bio-markers><biologic marker><biological signal transduction><biomarker><cancer cell><cdc Genes><cdk Proteins><cell behavior><cellular behavior><clinical biomarkers><clinically useful biomarkers><dreaming><flow cytophotometry><gain of function><genome mutation><glycogen synthase a kinase><hydroxyalkyl protein kinase><interest><knock-down><knockdown><loss of function><malignancy><mouse model><murine model><mutant><neoplasm/cancer><novel><ontogeny><ovarian cancer><overexpress><overexpression><oviduct><patient response><patient specific response><phosphorylase b kinase kinase><predictive biomarkers><predictive marker><predictive molecular biomarker><prognostic biomarker><prognostic indicator><protein complex><protein function><regulatory gene><resistance to therapy><resistant to therapy><response to treatment><responsive patient><shRNA><short hairpin RNA><small hairpin RNA><social role><therapeutic resistance><therapeutic response><therapeutic target><therapy resistant><trans acting element><transcription factor><treatment resistance><treatment response><tumor>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sunil Kumar

ST. JOHN'S UNIVERSITY, QUEENS, NY

Exploratory lead · 10/100
Active award
$187,500
FY 2025

Project Title

Investigating the role of Lipocalin Prostaglandin D2 Synthase and its metabolite PGD2 in non-alcoholic fatty liver disease

Grant Number:

5R16GM150498-02

Activity Code:

R16

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/10/2024

End Date:

6/30/2028

Project Abstract

PROJECT SUMMARY/ABSTRACT Despite non-alcoholic fatty liver disease (NAFLD) being the most common chronic liver disease worldwide, molecular mechanisms contributing to its etiology and progression are still unclear. This gap in knowledge has prevented the understanding of basic biology, pathogenesis,...

Research Terms

<APOE><Address><Affect><Agonist><Apo-E><ApoE protein><Apolipoprotein E><Arachidonic Acid Cyclooxygenase><Biology><Causality><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Control Groups><Cyclo-Oxygenase><Cyclooxygenase><D2 receptor><DRD2 Receptor><Data><Dedications><Development><Diabetes Mellitus><Disease><Disorder><Dopamine D2 Receptor><Drug Therapy><Dysfunction><Etiology><Exhibits><FDA approved><Fat-Restricted Diet><Fatty Acid Cyclo-Oxygenase><Functional disorder><Future><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G-Protein-Coupled Receptors><GPCR><Gene Expression><Glycolysis><Glycoproteins><Goals><Hep G2><HepG2><HepG2 cell line><Hepatic><High Fat Diet><Humulin R><Hydroperoxide Cyclase><Immune response><In Vitro><Incidence><Individual><Injury to Liver><Insulin><Insulin Resistance><Intracellular Communication and Signaling><Isomerism><KO mice><Knock-out Mice><Knockout Mice><Knowledge><Learning><Link><Lipids><Liver><Low-Fat Diet><Metabolic><Metabolic Diseases><Metabolic Disorder><Mice><Mice Mammals><Modeling><Molecular><Murine><Mus><NAFLD><Names><Novolin R><Null Mouse><Obesity><PGD2><PGH Synthase><PGH2 Synthetase><Pathogenesis><Pathway interactions><Patients><Pharmacological Treatment><Pharmacotherapy><Physiologic><Physiological><Physiology><Physiopathology><Play><Population><Prostaglandin Cyclo-Oxygenase><Prostaglandin Cyclooxygenase><Prostaglandin D2><Prostaglandin Endoperoxide Synthetase><Prostaglandin G-H Synthase><Prostaglandin H Synthase><Prostaglandin H2 Synthetase><Prostaglandin Synthase><Prostaglandin Synthetase><Prostaglandin-Endoperoxide Synthase><Proteins><Receptor Protein><Regular Insulin><Regulation><Research><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Testing><Therapeutic><Thesaurismosis><Triacylglycerol><Triglycerides><Universities><Weight Gain><Weight Increase><Work><adipogenesis><adiposity><allergen response><allergic response><allergy response><antagonism><antagonist><biological signal transduction><body weight gain><body weight increase><causation><chronic hepatic disease><chronic hepatic disorder><chronic liver disease><chronic liver disorder><compare to control><comparison control><corpulence><curative intervention><curative therapeutic><curative therapy><curative treatments><db/db mouse><developmental><diabetes><disease causation><disease phenotype><drug intervention><drug treatment><fat metabolism><fatty acid oxidation><fatty liver disease><glucose metabolism><graduate student><hepatic body system><hepatic damage><hepatic injury><hepatic organ system><host response><human disease><immune system response><immunoresponse><in vitro Model><innovate><innovation><innovative><insulin resistant><insulin signaling><insulin tolerance><isomer><life style intervention><lifestyle intervention><lipid biosynthesis><lipid metabolism><lipogenesis><liver damage><liver injury><mRNA Expression><metabolism disorder><metabolism measurement><metabolomics><metabonomics><name><named><naming><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutic target><new therapeutics><new therapy><new therapy approaches><new therapy target><new treatment approach><new treatment strategy><next generation therapeutics><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutic target><novel therapeutics><novel therapy><novel therapy approach><novel therapy target><overexpress><overexpression><pathophysiology><pathway><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><prevent><preventing><protein expression><receptor><social role><therapeutic target><transcriptomics><undergraduate research experience><undergraduate research opportunities><undergraduate research programs><wt gain>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Larisa Litovchick

VIRGINIA COMMONWEALTH UNIVERSITY, RICHMOND, VA

Exploratory lead · 0/100
$172,376
FY 2024

Project Title

Role of the DREAM complex in the lung tumor suppression

Grant Number:

5R21CA277518-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/3/2023

End Date:

1/31/2026

Project Abstract

ABSTRACT Lung cancer is the major cause of cancer deaths in the U.S. and worldwide. The most common types of lung cancer are non-small cell lung carcinoma (NSCLC, 84%) and small cell lung carcinoma (SCLC, 13%). NSCLC includes two major histological subtypes, adenocarcinoma (AC), and squamous cell ca...

Research Terms

<ATP-protein phosphotransferase><Address><Adenocarcinoma Cell><Alleles><Allelomorphs><Animals><Antioncogene Protein p53><Binding><Breeding><Bypass><C-K-RAS><CDK4I><CDKN2><CDKN2 Genes><CDKN2A><CDKN2A gene><CMM2><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cancer Cause><Cancer Etiology><Cancers><Cas nuclease technology><Cell Aging><Cell Body><Cell Communication and Signaling><Cell Cycle><Cell Cycle Arrest><Cell Cycle Genes><Cell Cycle Progression><Cell Division Cycle><Cell Division Cycle Genes><Cell Growth in Number><Cell Multiplication><Cell Proliferation><Cell Senescence><Cell Signaling><Cell Survival><Cell Viability><Cells><Cellular Aging><Cellular Proliferation><Cellular Senescence><Cellular Tumor Antigen P53><Cellular injury><Cessation of life><Chronic><Clinical Data><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Communities><Complex><Copy Number Polymorphism><Cyclin-Dependent Kinase Inhibitor 2A Gene><DNA Damage><DNA Damage Repair><DNA Injury><DNA Repair><DNA Repair Gene><DNA repair protein><Data Analyses><Data Analysis><Death><Detection><Development><Diagnostic><Disease><Disorder><Early Diagnosis><Environmental Factor><Environmental Risk Factor><Epidermoid Carcinoma><Epithelial Cell Proliferation><Epithelial Cells><Experimental Models><Exposure to><Future><GEM model><GEMM model><Gene Action Regulation><Gene Expression><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Gene Targeting><Gene Transcription><Generalized Growth><Genes><Genetic><Genetic Alteration><Genetic Change><Genetic Transcription><Genetic defect><Genetically Engineered Mouse><Genome><Genotoxic Stress><Growth><Growth Agents><Growth Factor><Growth Substances><Heterozygote><Histologic><Histologically><History><Human><Human Cell Line><INK4><INK4A><Immune><Immunes><In Vitro><Inflammatory><Intracellular Communication and Signaling><Investigation><K-RAS2A><K-RAS2B><K-Ras><K-Ras 2A><K-Ras-2 Oncogene><KRAS><KRAS2><KRAS2 gene><Ki-RAS><Kinase Family Gene><Kinases><Knock-in><Knowledge><L-Serine><Lesion><Lung><Lung Adenocarcinoma><Lung Neoplasms><Lung Respiratory System><Lung Tumor><MTS1><MTS1 Genes><Malignant><Malignant - descriptor><Malignant Glandular Cell><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of lung><Measurement><Mediating><Messenger RNA><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Molecular Interaction><Molecular Tumor Suppression><Mouse Cell Line><Murine><Mus><Mutant Strains Mice><Mutate><Mutation><NSCLC><NSCLC - Non-Small Cell Lung Cancer><Non-Small Cell Lung Cancer><Non-Small-Cell Lung Carcinoma><Oat cell carcinoma><Oncogene K-Ras><Oncogenesis><Oncogenic><Oncoprotein p53><Outcome><P105-RB><P53><PP110><Pathogenesis><Pathway interactions><Phenotype><Phosphoprotein P53><Phosphoprotein pp53><Phosphorylation><Phosphotransferase Gene><Phosphotransferases><Physiologic><Physiological><Planocellular Carcinoma><Play><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Proliferating><Proliferation Marker><Protein Family><Protein Kinase><Protein Phosphorylation><Protein TP53><Proteins><Proteins Growth Factors><Pulmonary Cancer><Pulmonary Neoplasms><Pulmonary malignant Neoplasm><RASK2><RNA Expression><Radiation><Radiation induced damage><Radon><Rb Gene Product><Rb Protein><Rb1 Gene Product><Recording of previous events><Replicative Senescence><Repression><Repressor Proteins><Research><Respiratory Epithelium><Retinal Neuroblastoma><Retinoblastoma><Retinoblastoma Associated Protein><Retinoblastoma Protein><Risk Factors><Rn element><Role><Serine><Signal Transduction><Signal Transduction Systems><Signaling><Small Cell Lung Cancer><Smoker><Squamous Carcinoma><Squamous Cell Epithelioma><Squamous cell carcinoma><Staging><Structure of respiratory epithelium><TCGA><TP16><TP53><TP53 gene><TRP53><TSG9A><Testing><The Cancer Genome Atlas><Tissue Growth><Tobacco smoke><Tobacco smoking><Tobacco smoking behavior><Transcription><Transcription Repressor><Transcriptional Repressor><Transphosphorylases><Tumor Protein p53><Tumor Protein p53 Gene><Tumor Suppression><Tumor Suppressor Proteins><Unscheduled DNA Synthesis><airway epithelium><biological signal transduction><cancer initiation><cancer progression><cdc Genes><cell damage><cell injury><cellular damage><copy number variant><copy number variation><damage to cells><data interpretation><detection of nutrient><developmental><driver lesion><driver mutation><early detection><environmental risk><exposure to tobacco><genetic repressor><genetically engineered mouse model><genetically engineered murine model><genome editing><genome mutation><genomic editing><genotoxicity><glycogen synthase a kinase><heterozygosity><high reward><high risk><histories><hydroxyalkyl protein kinase><injury to cells><irradiation><knockin><lung cancer><lung carcinogenesis><lung histology><lung oat cell carcinoma><lung small cell neuroendocrine carcinoma><lung tumorigenesis><mRNA><mRNA Expression><malignancy><mouse model><mouse mutant><murine model><mutant><neoplasm progression><neoplasm/cancer><neoplastic><neoplastic progression><new approaches><novel><novel approaches><novel strategies><novel strategy><nutrient sensing><oat cell cancer><ontogeny><p14ARF><p16 Genes><p16INK4 Genes><p16INK4A Genes><p16INK4a><p53 Antigen><p53 Genes><p53 Tumor Suppressor><pRB><pathway><perception of nutrients><phosphorylase b kinase kinase><precancer><precancerous><premalignant><prevent><preventing><promoter><promotor><protein expression><protein p53><pulmonary><pulmonary histology><radiation damage><recruit><repair><repaired><repressor complex><respiratory tract epithelium><response><retina neuroblastoma><senescence><senescent><small cell lung carcinoma><small cell undifferentiated carcinoma><social role><survival outcome><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><tobacco exposure><tumor><tumor progression><tumor suppressor><tumorigenesis><tumorigenesis in the lung><v-Ki-RAS2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jae-Il Park

UNIVERSITY OF TX MD ANDERSON CAN CTR, HOUSTON, TX

Exploratory lead · 0/100
$81,000
FY 2025

Project Title

Calcium metabolism and lung cancer preneoplasia

Grant Number:

5R03CA279867-02

Activity Code:

R03

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2024

End Date:

12/31/2025

Project Abstract

PROJECT SUMMARY/ABSTRACT Lung cancer is the second deadliest cancer. Despite its prevalence and unfavorable consequences, current therapeutic approaches are limited. The proposed study aims to understand the biology of lung tumorigenesis and use that knowledge to lay a foundation to develop potentia...

Research Terms

<Abnormal Cell><Advanced Development><Animal Model><Animal Models and Related Studies><Antioncogene Protein p53><Area><Attention><B-MYB><BMYB><Binding><Biology><C-K-RAS><Calcium Ion Signaling><Calcium Signaling><Cancer Biology><Cancer Patient><Cancer Treatment><Cancers><Cell Body><Cell Communication and Signaling><Cell Cycle><Cell Division Cycle><Cell Growth in Number><Cell Multiplication><Cell Proliferation><Cell Signaling><Cells><Cellular Proliferation><Cellular Tumor Antigen P53><Ciclosporin><Complex><Core Protein><Creativeness><CsA><Cyclosporin A><Cyclosporine><Cyclosporine A><DNA Polymerase Delta Auxiliary Protein><DNA Therapy><Dimerization><Dissociation><Drug Therapy><FKHL16><FOXM1><FOXM1 gene><FOXM1B><Forkhead Box M1><Forkhead Box M1B Transcription Factor><Forkhead, Drosophila, Homolog-Like 16><Fostering><Foundations><G1 Arrest><G1 Block><Gene Activation><Gene Down-Regulation><Gene Transcription><Gene Transfer Clinical><Genes><Genetic Engineering><Genetic Engineering Biotechnology><Genetic Engineering Molecular Biology><Genetic Intervention><Genetic Transcription><Goals><HFH11><Health protection><In Vitro><Intracellular Communication and Signaling><K-RAS2A><K-RAS2B><K-Ras><K-Ras 2A><K-Ras-2 Oncogene><KRAS><KRAS2><KRAS2 gene><Ki-RAS><Knowledge><Lung Adenocarcinoma><MGC15600><MYBL2><MYBL2 gene><Macromolecular Protein Complexes><Malignant Cell><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of lung><Mediating><Mediator><Mission><Modeling><Molecular><Molecular Interaction><Multiprotein Complexes><NF-AT><NF-AT proteins><NFAT Pathway><NFAT and Hypertrophy of the heart (Transcription in the broken heart)><NFAT proteins><NFAT-1><NFATC proteins><NIH><NSCLC><NSCLC - Non-Small Cell Lung Cancer><National Institutes of Health><Neoplasms><Non-Small Cell Lung Cancer><Non-Small-Cell Lung Carcinoma><Normal Cell><Nuclear Translocation><Oncogene K-Ras><Oncogenesis><Oncogenic><Oncoprotein p53><P130><P53><PCNA-Cyclin><Patients><Pharmacological Treatment><Pharmacotherapy><Phosphoprotein P53><Phosphoprotein pp53><Play><Prevalence><Process><Proliferating Cell Nuclear Antigen><Protein Dimerization><Protein TP53><Proteins><Public Health><Pulmonary Cancer><Pulmonary malignant Neoplasm><RASK2><RBL2><RBL2 gene><RNA Expression><Rb2><Recombinant DNA Technology><Repression><Research><Retinal Neuroblastoma><Retinoblastoma><Retinoblastoma-Like 2><Role><Sandimmun><SangCya><Signal Transduction><Signal Transduction Systems><Signaling><Somatic Cell><Survival Rate><TP53><TP53 gene><TRIDENT gene><TRIDENT protein><TRP53><Testing><Therapeutic><Transactivation><Transcription><Transcription Repression><Treatment Protocols><Treatment Regimen><Treatment Schedule><Tumor Protein p53><Tumor Protein p53 Gene><United States National Institutes of Health><anti-cancer therapy><biological signal transduction><calcium metabolism><cancer cell><cancer progression><cancer therapy><cancer-directed therapy><creativity><cytoplasmic nuclear factor of activated T-cells><drug candidate><drug intervention><drug repositioning><drug repurposing><drug treatment><feasibility testing><gene repair therapy><gene repression><gene therapy><gene-based therapy><genetic therapy><genetically engineered><genomic therapy><in vivo><inhibitor><innovate><innovation><innovative><interest><lung cancer><lung tumorigenesis><malignancy><model of animal><neoplasia><neoplasm progression><neoplasm/cancer><neoplastic growth><neoplastic progression><neoral><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutics><novel therapy><nuclear factors of activated T-cells><p53 Antigen><p53 Genes><p53 Tumor Suppressor><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><promoter><promotor><protein p53><repurposing agent><repurposing medication><retina neuroblastoma><sandimmune><screening><screenings><social role><trans-activation><transcription factor NF-AT><transcriptomics><tumor initiation><tumor progression><tumorigenesis><tumorigenesis in the lung><v-Ki-RAS2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog>
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Search NIH grants by PI name

Looking for a specific principal investigator? The keyword search above looks up funded projects by topic. To search NIH grants by PI name (last name, first + last name, or partial name) and see every active and recent NIH award for that researcher, use the dedicated PI Funding Status tool.

How to Use PI Funding Data for Career Decisions

Finding the right principal investigator is one of the most important decisions in an academic career. Whether you are a postdoc looking for a mentor, a graduate student choosing a rotation lab, or a collaborator seeking a co-PI, NIH funding data provides objective signals about which investigators have active research programs and resources to support new team members.

A PI with a recently awarded R01 or equivalent grant is more likely to have budget for new personnel than one whose funding ended two years ago. The activity code tells you the type of grant: R01 and R35 awards typically support multiple lab members, while K-series awards are individual career development grants that may not fund additional positions. Understanding these distinctions helps you interpret search results accurately.

Look beyond the dollar amount. A $500,000 per year R01 at a high-cost institution may support fewer positions than a $300,000 award at a university with lower overhead rates. The project abstract and public health relevance statement reveal whether the PI's research direction aligns with your interests and expertise.

Understanding PI Grant Portfolios

A PI's grant portfolio reveals more than individual awards. Investigators with multiple active grants often run larger labs with more diverse projects, which can mean more opportunities for trainees. However, a PI with a single well-funded grant may offer more focused mentorship and a clearer path to publications.

Multi-PI grants (those with more than one principal investigator listed) indicate collaborative research and may involve trainees from multiple institutions. These can be excellent opportunities for interdisciplinary training but may also mean split attention from any single mentor.

Pay attention to the timing of awards. A PI who just received a new five-year R01 is in a different position than one whose grant ends next year. New awards often correspond to lab expansion and active recruiting, making them ideal targets for job seekers. The start and end dates shown in each result help you assess this timing.

Best Practices for Contacting Funded PIs

Once you identify a promising PI through this tool, the next step is outreach. NIH public records do not include email addresses, but you can usually find contact information through the PI's institutional profile page, lab website, or recent publications. Google Scholar, PubMed, and the PI's department website are reliable starting points.

When reaching out, reference the specific grant that caught your attention. Mentioning the project title and explaining how your skills relate to the funded work shows that you have done your homework. Keep your initial message concise: introduce yourself, explain your interest, attach your CV, and ask whether they anticipate openings.

Timing matters. Contacting a PI within the first year of a new award is ideal, as this is when they are most likely to be recruiting. If you find multiple promising PIs in the same field, prioritize those with the most recent award notices and activity codes that support trainee positions such as R01, U01, or P-series grants.

Frequently Asked Questions About PI Search

What does the opportunity score mean?

The opportunity score is a heuristic that combines award recency, funding amount, activity code type, and project characteristics to estimate how actionable a result might be for job seekers or collaborators. Higher scores suggest stronger signals, but always verify by reading the abstract and checking the PI's current lab page.

Why can't I find a PI I know has funding?

Name variations are the most common cause. Try searching with just the last name, or use different formats like "Smith, John" versus "John Smith." Some PIs also publish under different name variations or may have awards under a previous institutional affiliation.

Does this tool show all NIH-funded PIs?

The tool searches NIH RePORTER data for the keyword and year range you specify. It returns PIs whose funded projects match your search terms. PIs with grants in unrelated areas or whose projects use different terminology will not appear in keyword-filtered results.

What is the difference between "Likely hiring" and "Training-friendly" filters?

"Likely hiring" flags PIs with large new awards or activity codes typically associated with lab expansion. "Training-friendly" identifies awards that include training components or are at institutions known for postdoctoral programs. Both are heuristic filters to help prioritize your outreach.

How to use this well

Start broad, then narrow. Search a field first, then refine by timeframe once you understand who is currently active.

After you find a promising PI, cross-check them in Check PI Funding and review their institution, mechanism type, and project abstracts before reaching out.

What a match means

A result means the keyword appears relevant to the funded project data we searched. It does not guarantee the PI is hiring or that the grant is still active.

Use the abstract, award year, mechanism, and organization context to decide whether the record is strategically relevant.

Data limits

NIH records can lag, institutional names can vary, and some investigators publish or file awards under multiple name formats.

For details on source coverage and refresh cadence, read Data & Methodology.

Related guides

Companion guides for turning a PI search result into useful outreach or a job lead.

Career Guide8 min read

How Postdocs Can Find PIs with New NIH Funding

A tactical job-search guide for identifying recently funded labs, judging fit, and timing outreach to principal investigators.

Career Guide7 min read

How to Contact a PI: Finding Emails and Crafting the Perfect Message

Emailing strategies, outreach examples, and a workflow for turning NIH funding signals into focused PI conversations.

Career Guide10 min read

How to Read a New NIH Award Like a Hiring Signal

A practical framework for using newly funded NIH awards to judge whether a lab may be expanding, hiring, or worth contacting now.

Funding Strategy16 min read

How to Find NIH Funding Opportunities: A Step-by-Step Guide for Researchers

Learn how to find NIH funding opportunities using the NIH Guide, Grants.gov, FOAs, NIH RePORTER, and program officer outreach.

Principal investigators who received NIH awards in the last 90 days, organized by research area. Use this as a starting point for postdoc searches, collaborator outreach, or competitor scans. Counts and labs refresh daily.

Alzheimer's disease

Neurodegeneration, biomarkers, and disease-modifying therapies.

  • Carlos Cruchaga WASHINGTON UNIVERSITY, MO
    CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"
    $101,153 · awarded Feb 25, 2026 · 3U01AG084514-01A1S1
  • Carlos Cruchaga WASHINGTON UNIVERSITY, MO
    CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"
    $3,086,339 · awarded Feb 19, 2026 · 1U01AG084514-01A1
  • HARALD SONTHEIMER UNIVERSITY OF VIRGINIA, VA
    Extracellular matrix and memory impairments in Alzheimer disease
    $709,066 · awarded Apr 7, 2026 · 5R01AG085359-03
  • Keith Josephs MAYO CLINIC ROCHESTER, MN
    The neurobiology of two distinct subtypes of neurodegenerative apraxia of speech: phenotypes of Alzheimer disease related 4-repeat tauopathies
    $643,670 · awarded Apr 1, 2026 · 5R01DC014942-09
  • DMITRIY YABLONSKIY WASHINGTON UNIVERSITY, MO
    Deep-Learning-Augmented Quantitative Gradient Recalled Echo (DLA-qGRE) MRI for in vivo Clinical Evaluation of Brain Microstructural Neurodegeneration in Alzheimer Disease
    $661,985 · awarded Mar 3, 2026 · 4R01AG082030-02

CRISPR & gene editing

Therapeutic gene editing, base editing, and prime editing.

  • Changchun Liu UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT
    Asymmetric CRISPR Approach for Nucleic Acid Quantification
    $643,849 · awarded Mar 30, 2026 · 2R01EB023607-06A1
  • William Pu BOSTON CHILDREN'S HOSPITAL, MA
    A modular system for murine CRISPR genome and epigenome editing
    $267,000 · awarded Mar 27, 2026 · 5R21OD037909-02
  • Naama Aviram SLOAN-KETTERING INST CAN RESEARCH, NY
    Molecular mechanisms of memory formation and tolerance in CRISPR-Cas systems
    $249,000 · awarded Apr 2, 2026 · 5R00GM148720-04
  • Mats Ljungman UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
    Precision targeting of bladder cancer using CRISPR
    $582,849 · awarded Feb 17, 2026 · 5R01CA285730-03
  • Shannon Miller SCRIPPS RESEARCH INSTITUTE, THE, CA
    Development of potent and safe CRISPR tools for in vivo gene editing using directed evolution
    $230,000 · awarded May 5, 2026 · 5R21EB036298-03

Cancer immunotherapy

Checkpoint inhibitors, CAR-T, TIL therapy, and beyond.

  • TERRY SHEPPARD KEYSTONE SYMPOSIA, CO
    Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations
    $5,000 · awarded Mar 3, 2026 · 1R13CA310704-01
  • Veronika Fedirko UNIVERSITY OF TX MD ANDERSON CAN CTR, TX
    Gut Microbiome and Cancer Immunotherapy Outcomes in Advanced Renal Cell Carcinoma
    $927,329 · awarded Mar 3, 2026 · 5R01CA255322-05
  • Yuwen Zhu UNIVERSITY OF COLORADO DENVER, CO
    The GPR171 pathway in cancer immunotherapy
    $355,706 · awarded Apr 2, 2026 · 5R01CA279398-04
  • ANDREW WIEMER UNIVERSITY OF CONNECTICUT STORRS, CT
    Synthesis and evaluation of BTN3A1 ligands for cancer immunotherapy
    $374,171 · awarded May 1, 2026 · 5R01CA266138-05
  • Wei Hu YALE UNIVERSITY, CT
    Novel Treg inactivating approach for cancer immunotherapy via targeted protein degradation
    $482,312 · awarded Apr 6, 2026 · 1R01CA295942-01A1

GLP-1 & metabolic disease

Diabetes, obesity, and weight-loss therapeutic mechanisms.

  • ZHIPING PANG RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ
    Synaptic and circuit mechanisms of central GLP-1 signaling in energy balance
    $479,051 · awarded Apr 23, 2026 · 5R01DK131452-05
  • Madhusmita Misra UNIVERSITY OF VIRGINIA, VA
    Bone metabolism in adolescents undergoing GLP-1 receptor agonist therapy
    $471,776 · awarded Apr 24, 2026 · 5R01HD118635-07
  • STEVEN SCHWENDEMAN UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
    Remote Loading of Melanocortin and GLP-1 Peptides in Polymers for Treatment of Obesity
    $231,000 · awarded Apr 17, 2026 · 1R56DK141545-01A1
  • Jessica Barson DREXEL UNIVERSITY, PA
    Suppression of ethanol dependence-induced maladaptive appetitive and consummatory behavior by the GLP-1 system
    $564,306 · awarded May 5, 2026 · 1R01AA031732-01A1
  • MICHAEL CAMILLERI MAYO CLINIC ROCHESTER, MN
    A Randomized, placebo-controlled trial of the effects of Long-Acting GLP-1 or Dual Incretin (GLP-1 and GIP) Modulation on Gastrointestinal Functions and Relationship to Weight Loss
    $322,800 · awarded Apr 9, 2026 · 5R01DK142606-02

Long COVID

Post-acute sequelae and chronic infection-driven illness.

  • Alexei Tumanov UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX
    Lymphotoxin-dependent control of long COVID
    $234,715 · awarded Feb 13, 2026 · 1R21AI185790-01A1
  • Amal Amer OHIO STATE UNIVERSITY, OH
    Role of the Non-canonical Inflammasome in SARS-CoV-2-mediated Pathology and Coagulopathy
    $2,974,582 · awarded Apr 21, 2026 · 5P01AI175399-03
  • Alba Azola JOHNS HOPKINS UNIVERSITY, MD
    Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 onset ME/CFS versus Pre-Pandemic ME/CFS Patients
    $633,378 · awarded Apr 17, 2026 · 1R01NS147100-01
  • DANIELLE REED MONELL CHEMICAL SENSES CENTER, PA
    Inflammation and chemosensory loss
    $2,654,249 · awarded Feb 26, 2026 · 1P50DC022549-01A1
  • Jarred Younger UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL
    Low-dose naltrexone (LDN) for the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
    $556,686 · awarded Mar 6, 2026 · 1UG3NS141843-01A1